Publications by authors named "Martin Schumacher"

100Publications

Quantification and interpretation of attributable mortality in core clinical infectious disease journals.

Lancet Infect Dis 2020 Sep 8. Epub 2020 Sep 8.

Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1473-3099(20)30485-0DOI Listing
September 2020

Which patients to sample in clinical cohort studies when the number of events is high and measurement of additional markers is constrained by limited resources.

Cancer Med 2020 Oct 19;9(20):7398-7406. Epub 2020 Aug 19.

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cam4.3381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571814PMC
October 2020

Doug Altman: Driving critical appraisal and improvements in the quality of methodological and medical research.

Biom J 2020 Jul 8. Epub 2020 Jul 8.

Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences, University of Oxford, Oxford, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bimj.202000053DOI Listing
July 2020

Comparison of complex modeling strategies for prediction of a binary outcome based on a few, highly correlated predictors.

Biom J 2020 05 30;62(3):568-582. Epub 2020 Mar 30.

Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bimj.201800243DOI Listing
May 2020

A multi-state model analysis of the time from ethical approval to publication of clinical research studies.

PLoS One 2020 27;15(3):e0230797. Epub 2020 Mar 27.

Institute for Prevention and Cancer Epidemiology, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0230797PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100954PMC
June 2020

On the relation between the cause-specific hazard and the subdistribution rate for competing risks data: The Fine-Gray model revisited.

Biom J 2020 05 4;62(3):790-807. Epub 2020 Mar 4.

Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bimj.201800274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216972PMC
May 2020

Recovery of original individual person data (IPD) inferences from empirical IPD summaries only: Applications to distributed computing under disclosure constraints.

Stat Med 2020 04 14;39(8):1183-1198. Epub 2020 Jan 14.

Institute of Medical Biometry and Statistics, Faculty of Medicine, Medical Center University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/sim.8470DOI Listing
April 2020

A multi-state model based reanalysis of the Framingham Heart Study: Is dementia incidence really declining?

Eur J Epidemiol 2019 Nov 14;34(11):1075-1083. Epub 2019 Oct 14.

Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Stefan-Meier-Strasse 26, 79104, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00567-6DOI Listing
November 2019

A multivariable approach for risk markers from pooled molecular data with only partial overlap.

BMC Med Genet 2019 07 19;20(1):128. Epub 2019 Jul 19.

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg, Stefan-Meier-Straße 26, Freiburg, 79104, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12881-019-0849-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642584PMC
July 2019

Exposure density sampling: Dynamic matching with respect to a time-dependent exposure.

Stat Med 2019 09 17;38(22):4390-4403. Epub 2019 Jul 17.

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/sim.8305DOI Listing
September 2019

The population-attributable fraction for time-dependent exposures using dynamic prediction and landmarking.

Biom J 2020 05 19;62(3):583-597. Epub 2019 Jun 19.

Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bimj.201800252DOI Listing
May 2020

The population-attributable fraction for time-dependent exposures and competing risks-A discussion on estimands.

Stat Med 2019 09 4;38(20):3880-3895. Epub 2019 Jun 4.

Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/sim.8208DOI Listing
September 2019

Estimands to quantify prolonged hospital stay associated with nosocomial infections.

BMC Med Res Methodol 2019 05 31;19(1):111. Epub 2019 May 31.

Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg, Stefan-Meier 26, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12874-019-0752-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544970PMC
May 2019

Penalized logistic regression with low prevalence exposures beyond high dimensional settings.

PLoS One 2019 20;14(5):e0217057. Epub 2019 May 20.

Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0217057PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527211PMC
February 2020

Dynamic prediction: A challenge for biostatisticians, but greatly needed by patients, physicians and the public.

Biom J 2020 05 25;62(3):822-835. Epub 2019 Mar 25.

Department of Hematology, Oncology and Stem Cell Transplantation, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bimj.201800248DOI Listing
May 2020

Analyzing the impact of duration of ventilation, hospitalization, and ventilation episodes on the risk of pneumonia.

Infect Control Hosp Epidemiol 2019 03 18;40(3):301-306. Epub 2019 Feb 18.

Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center,University of Freiburg,Frieburg,Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/ice.2018.360DOI Listing
March 2019

RE: "RISK-SET MATCHING TO ASSESS THE IMPACT OF HOSPITAL-ACQUIRED BLOODSTREAM INFECTIONS".

Am J Epidemiol 2019 06;188(6):1192-1193

Institute for Medical Biometry and Statistics, University Medical Center Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/aje/kwz035DOI Listing
June 2019

Follow-on rifaximin for the prevention of recurrence following standard treatment of infection with : a competing risks analysis provides a full picture of possible treatment effects.

Gut 2020 02 28;69(2):398-400. Epub 2018 Dec 28.

Faculty of Medicine and Medical Center, Institute for Medical Biometry and Statistics, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/gutjnl-2018-317839DOI Listing
February 2020

Day and Night: Metabolic Profiles and Evolutionary Relationships of Six Axenic Non-Marine Cyanobacteria.

Genome Biol Evol 2019 01 1;11(1):270-294. Epub 2019 Jan 1.

Abteilung Protisten und Cyanobakterien, Leibniz-Institut DSMZ - Deutsche Sammlung von Mikroorganismen und Zellkulturen, Braunschweig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/gbe/evy275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349668PMC
January 2019

Nested exposure case-control sampling: a sampling scheme to analyze rare time-dependent exposures.

Lifetime Data Anal 2020 01 13;26(1):21-44. Epub 2018 Nov 13.

Ulm University, Helmholtzstrasse 20, 89081, Ulm, Germany.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10985-018-9453-4
Publisher Site
http://dx.doi.org/10.1007/s10985-018-9453-4DOI Listing
January 2020

Early Recoil After Balloon Angioplasty of Erection-Related Arteries in Patients With Arteriogenic Erectile Dysfunction.

J Endovasc Ther 2018 12 22;25(6):710-715. Epub 2018 Oct 22.

5 Clinic for Angiology, University Hospital of Zurich and University of Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1526602818807704DOI Listing
December 2018

Cohort studies were found to be frequently biased by missing disease information due to death.

J Clin Epidemiol 2019 01 22;105:68-79. Epub 2018 Sep 22.

Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Stefan-Meier-Str. 26, 79104 Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jclinepi.2018.09.010DOI Listing
January 2019

Improving nested case-control studies to conduct a full competing-risks analysis for nosocomial infections.

Infect Control Hosp Epidemiol 2018 10 30;39(10):1196-1201. Epub 2018 Aug 30.

1Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center,University of Freiburg,Freiburg,Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/ice.2018.186DOI Listing
October 2018

Simulation shows undesirable results for competing risks analysis with time-dependent covariates for clinical outcomes.

BMC Med Res Methodol 2018 07 16;18(1):79. Epub 2018 Jul 16.

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg, Stefan-Meier-Str. 26, Freiburg, 79104, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12874-018-0535-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048847PMC
July 2018

The Impact of Early Adequate Treatment on Extubation and Discharge Alive of Patients With Pseudomonas aeruginosa-Related Ventilator-Associated Pneumonia.

Crit Care Med 2018 10;46(10):1643-1648

Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0000000000003305DOI Listing
October 2018

Intravesical BCG treatment causes a long-lasting reduction of recurrence and progression in patients with high-risk non-muscle-invasive bladder cancer.

World J Urol 2019 Jan 15;37(1):155-163. Epub 2018 Jun 15.

Division of Clinical Chemistry, Department of Laboratory Medicine, Karolinska Institutet, Karolinska University Hospital, 141 86, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00345-018-2375-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6510863PMC
January 2019

Bias due to censoring of deaths when calculating extra length of stay for patients acquiring a hospital infection.

BMC Med Res Methodol 2018 05 30;18(1):49. Epub 2018 May 30.

Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12874-018-0500-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975458PMC
May 2018

A simulation approach for power calculation in large cohort studies based on multistate models.

Biom J 2018 07 2;60(4):671-686. Epub 2018 May 2.

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center-University of Freiburg, Germany.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/bimj.201700074
Publisher Site
http://dx.doi.org/10.1002/bimj.201700074DOI Listing
July 2018

Methodological challenges in using point-prevalence versus cohort data in risk factor analyses of nosocomial infections.

Ann Epidemiol 2018 07 3;28(7):475-480.e1. Epub 2018 Apr 3.

Institute of Medical Biometry and Medical Informatics, University Medical Center Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.annepidem.2018.03.017DOI Listing
July 2018

Induction of extracranial arteriogenesis by an arteriovenous fistula in a pig model.

Atherosclerosis 2018 05 3;272:87-93. Epub 2018 Mar 3.

Charité-Universitätsmedizin Berlin, CCR - Center for Cardiovascular Research, Dept. of Internal Medicine/Cardiology, Berlin, Germany; Department for Angiology, Brandenburg Medical School, Brandenburg/Havel, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atherosclerosis.2018.03.008DOI Listing
May 2018

Control procedures and estimators of the false discovery rate and their application in low-dimensional settings: an empirical investigation.

BMC Bioinformatics 2018 03 2;19(1):78. Epub 2018 Mar 2.

Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center, University of Freiburg, Hugstetter Str. 49, 79106, Freiburg, Germany.

View Article

Download full-text PDF

Source
https://bmcbioinformatics.biomedcentral.com/articles/10.1186
Publisher Site
http://dx.doi.org/10.1186/s12859-018-2081-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833079PMC
March 2018

A wild bootstrap approach for the Aalen-Johansen estimator.

Biometrics 2018 09 16;74(3):977-985. Epub 2018 Feb 16.

Institute of Statistics, Ulm University, Ulm, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/biom.12861DOI Listing
September 2018

Intravesical cidofovir application in BK virus cystitis after allogeneic hematopoetic stem cell transplantation (HSCT) is safe and highly effective.

Bone Marrow Transplant 2018 04 12;53(4):495-498. Epub 2018 Jan 12.

Medical Clinic III for Oncology, Hematology, Immunoncology and Rheumatology, University Hospital Bonn (UKB), Bonn, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41409-017-0044-xDOI Listing
April 2018

Assessing Noninferiority in Treatment Trials for Severe Infectious Diseases: an Extension to the Entire Follow-Up Period Using a Cure-Death Multistate Model.

Antimicrob Agents Chemother 2018 01 21;62(1). Epub 2017 Dec 21.

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.01691-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740315PMC
January 2018

RE: "Selective Cutoff Reporting in Studies of Diagnostic Test Accuracy: A Comparison of Conventional and Individual-Patient-Data Meta-Analyses of the Patient Health Questionnaire - 9 Depression Screening Tool".

Am J Epidemiol 2017 10;186(7):894

Institute for Medical Biometry and Statistics, Medical Faculty and Medical Center - University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/aje/kwx275DOI Listing
October 2017

Sole reliance on I may mislead.

Heart 2017 09;103(18):1471-1472

Faculty of Medicine and Medical Center, Institute for Medical Biometry and Statistics, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/heartjnl-2017-311767DOI Listing
September 2017

Modelling two cause-specific hazards of competing risks in one cumulative proportional odds model?

Stat Med 2017 Nov 22;36(27):4353-4363. Epub 2017 Aug 22.

Institute of Statistics, Ulm University, Helmholtzstr. 18, 89081, Ulm, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/sim.7437DOI Listing
November 2017

Basic parametric analysis for a multi-state model in hospital epidemiology.

BMC Med Res Methodol 2017 Jul 20;17(1):111. Epub 2017 Jul 20.

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg, Stefan-Meier Str. 26, Freiburg, 79104, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12874-017-0379-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520301PMC
July 2017

A flexible multivariate random effects proportional odds model with application to adverse effects during radiation therapy.

Biom J 2017 Nov 10;59(6):1339-1351. Epub 2017 Jul 10.

Institute for Medical Biometry and Statistics, University of Freiburg, Stefan-Meier-Str. 26, 79104, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bimj.201600142DOI Listing
November 2017

Multistate Modeling to Analyze Nosocomial Infection Data: An Introduction and Demonstration.

Infect Control Hosp Epidemiol 2017 08 21;38(8):953-959. Epub 2017 Jun 21.

Faculty of Medicine and Medical Center,Institute for Medical Biometry and Statistics,University of Freiburg,Freiburg,Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/ice.2017.107DOI Listing
August 2017

The time-dependent "cure-death" model investigating two equally important endpoints simultaneously in trials treating high-risk patients with resistant pathogens.

Pharm Stat 2017 07 9;16(4):267-279. Epub 2017 Jun 9.

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/pst.1809
Publisher Site
http://dx.doi.org/10.1002/pst.1809DOI Listing
July 2017

Competing risks need to be considered in survival analysis models for cardiovascular outcomes.

J Thorac Cardiovasc Surg 2017 06 3;153(6):1427-1431. Epub 2017 Feb 3.

Institute of Biometry and Medical Statistics, Medical Center, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jtcvs.2016.12.039DOI Listing
June 2017

The combined association of alcohol consumption with dementia risk is likely biased due to lacking account of death cases.

Eur J Epidemiol 2017 07 15;32(7):627-629. Epub 2017 May 15.

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-017-0252-0DOI Listing
July 2017

Erectile dysfunction - overview from a cardiovascular perspective.

Vasa 2017 Aug 10;46(5):347-353. Epub 2017 May 10.

6 Vascular Institute Central Switzerland, Aarau, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1024/0301-1526/a000627DOI Listing
August 2017

Changes in Rates of Ventilator-Associated Pneumonia.

JAMA 2017 Apr;317(15):1580-1581

Institute for Medical Biometry and Statistics, University of Freiburg Medical Center, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jama.2017.2411DOI Listing
April 2017

Erratum to: Methods for evaluating medical tests and biomarkers.

Authors:
Gowri Gopalakrishna Miranda Langendam Rob Scholten Patrick Bossuyt Mariska Leeflang Anna Noel-Storr James Thomas Iain Marshall Byron Wallace Penny Whiting Clare Davenport Mariska Leeflang Gowri GopalaKrishna Isabel de Salis Sue Mallett Robert Wolff Penny Whiting Richard Riley Marie Westwood Jos Kleinen Gary Collins Hans Reitsma Karel Moons Antonia Zapf Annika Hoyer Katharina Kramer Oliver Kuss J Ensor J J Deeks E C Martin R D Riley Gerta Rücker Susanne Steinhauser Martin Schumacher Richard Riley Joie Ensor Kym Snell Brian Willis Thomas Debray Karel Moons Jon Deeks Gary Collins Lavinia Ferrante di Ruffano Brian Willis Clare Davenport Sue Mallett Sian Taylor-Phillips Chris Hyde Jon Deeks Sue Mallett Stuart A Taylor Gauraang Batnagar Sian Taylor-Phillips Lavinia Ferrante Di Ruffano Farah Seedat Aileen Clarke Jon Deeks Sarah Byron Frances Nixon Rebecca Albrow Thomas Walker Carla Deakin Chris Hyde Zhivko Zhelev Harriet Hunt Lavinia Ferrante di Ruffano Yaling Yang Lucy Abel James Buchanan Thomas Fanshawe Bethany Shinkins Laure Wynants Jan Verbakel Sabine Van Huffel Dirk Timmerman Ben Van Calster Mariska Leeflang Aeliko Zwinderman Patrick Bossuyt Jason Oke Jack O'Sullivan Rafael Perera Brian Nicholson Hannah L Bromley Tracy E Roberts Adele Francis Denniis Petrie G Bruce Mann Kinga Malottki Holly Smith Jon Deeks Lucinda Billingham Alice Sitch Sue Mallett Jon Deeks Oke Gerke Mie Holm-Vilstrup Eivind Antonsen Segtnan Ulrich Halekoh Poul Flemming Høilund-Carlsen Bernard G Francq Jon Deeks Alice Sitch Jac Dinnes Julie Parkes Walter Gregory Jenny Hewison Doug Altman William Rosenberg Peter Selby Julien Asselineau Paul Perez Aïssatou Paye Emilie Bessede Cécile Proust-Lima Christiana Naaktgeboren Joris de Groot Anne Rutjes Patrick Bossuyt Johannes Reitsma Karel Moons Gary Collins Emmanuel Ogundimu Jonathan Cook Yannick Le Manach Doug Altman Laure Wynants Yvonne Vergouwe Sabine Van Huffel Dirk Timmerman Ben Van Calster Romin Pajouheshnia Rolf Groenwold Karen Moons Johannes Reitsma Linda Peelen Ben Van Calster Daan Nieboer Yvonne Vergouwe Bavo De Cock Micael J Pencina Ewout W Steyerberg Jennifer Cooper Sian Taylor-Phillips Nick Parsons Chris Stinton Steve Smith Andy Dickens Rachel Jordan Alexandra Enocson David Fitzmaurice Alice Sitch Peymane Adab Bernard G Francq Charles Boachie Gaj Vidmar Karoline Freeman Martin Connock Sian Taylor-Phillips Rachel Court Aileen Clarke Joris de Groot Christiana Naaktgeboren Hans Reitsma Carl Moons Jessica Harris Andrew Mumford Zoe Plummer Kurtis Lee Barnaby Reeves Chris Rogers Veerle Verheyden Gianni D Angelini Gavin J Murphy Jeremy Huddy Melody Ni Katherine Good Graham Cooke Patrick Bossuyt George Hanna Jie Ma Doug Altman Gary Collins K G M Carl Moons Joris A H de Groot Sue Mallett Doug G Altman Johannes B Reitsma Gary S Collins Karel G M Moons Douglas G Altman Johannes B Reitsma Gary S Collins Adina Najwa Kamarudin Ruwanthi Kolamunnage-Dona Trevor Cox Melody Ni Jeremy Huddy Simone Borsci George Hanna Teresa Pérez M Carmen Pardo Angel Candela-Toha Alfonso Muriel Javier Zamora Sabina Sanghera Syed Mohiuddin Richard Martin Jenny Donovan Joanna Coast Mikyung Kelly Seo John Cairns Elizabeth Mitchell Alison Smith Judy Wright Peter Hall Michael Messenger Nicola Calder Nyantara Wickramasekera Karen Vinall-Collier Andrew Lewington Romin Pajouheshnia Johanna Damen Rolf Groenwold Karel Moons Linda Peelen Michael Messenger David Cairns Alison Smith Michelle Hutchinson Judy Wright Peter Hall Nicola Calder Cathie Sturgeon Liz Mitchel Rebecca Kift Sofia Christakoudi Manohursingh Rungall Paula Mobillo Rosa Montero Tjir-Li Tsui Sui Phin Kon Beatriz Tucker Steven Sacks Chris Farmer Terry Strom Paramit Chowdhury Irene Rebollo-Mesa Maria Hernandez-Fuentes Johanna A A G Damen Thomas P A Debray Pauline Heus Lotty Hooft Karel G M Moons Romin Pajouheshnia Johannes B Reitsma Rob J P M Scholten Johanna A A G Damen Lotty Hooft Ewoud Schuit Thomas P A Debray Gary S Collins Ioanna Tzoulaki Camille M Lassale George C M Siontis Virginia Chiocchia Corran Roberts Michael Maia Schlüssel Stephen Gerry James A Black Pauline Heus Yvonne T van der Schouw Linda M Peelen Karel G M Moons Johanna A A G Damen Thomas P A Debray Pauline Heus Lotty Hooft Karel G M Moons Romin Pajouheshnia Johannes B Reitsma Rob J P M Scholten Jie Ma Doug Altman Gary Collins Graeme Spence David McCartney Ann van den Bruel Daniel Lasserson Gail Hayward Werner Vach Antoinette de Jong Coreline Burggraaff Otto Hoekstra Josée Zijlstra Henrica de Vet Harriet Hunt Chris Hyde Sara Graziadio Joy Allen Louise Johnston Rachel O'Leary Michael Power Joy Allen Sara Graziadio Louise Johnson Rachel O'Leary Michael Power Ray Waters John Simpson Louise Johnston Joy Allen Sara Graziadio Rachel O'Leary Ray Waters Michael Power Sue Mallett Thomas R Fanshawe Peter Phillips Andrew Plumb Emma Helbren Steve Halligan Stuart A Taylor Alastair Gale Sue Mallett Peggy Sekula Douglas G Altman Willi Sauerbrei Sue Mallett Thomas R Fanshawe Julia R Forman Susan J Dutton Yemisi Takwoingi Elizabeth M Hensor Thomas E Nichols Bethany Shinkins Yaling Yang Lucy Abel Lavinia Ferrante Di Ruffano Thomas Fanshawe Emmanuelle Kempf Raphael Porcher Jennifer de Beyer Karel Moons Douglas Altman Hans Reitsma Sally Hopewell Willi Sauerbrei Gary Collins John Dennis Beverley Shields Angus Jones William Henley Ewan Pearson Andrew Hattersley Pauline Heus Johanna A A G Damen Romin Pajouheshnia Rob J P M Scholten Johannes B Reitsma Gary S Collins Douglas G Altman Karel G M Moons Lotty Hooft Beverley Shields John Dennis Angus Jones William Henley Ewan Pearson Andrew Hattersley Fueloep Scheibler Anne Rummer Sibylle Sturtz Robert Großelfinger Katie Banister Craig Ramsay Augusto Azuara-Blanco Jonathan Cook Charles Boachie Jennifer Burr Manjula Kumarasamy Rupert Bourne Ijeoma Uchegbu Simone Borsci Jennifer Murphy George Hanna Ijeoma Uchegbu Alex Carter Jen Murphy Melody Ni Joachim Marti Julie Eatock Ijeoma Uchegbu Julie Robotham Maria Dudareva Mark Gilchrist Alison Holmes Ijeoma Uchegbu Simone Borsci Phillip Monaghan Sarah Lord Andrew StJohn Sverre Sandberg Christa Cobbaert Lieselotte Lennartz Wilma Verhagen-Kamerbeek Christoph Ebert Patrick Bossuyt Andrea Horvath Kevin Jenniskens Christiana Naaktgeboren Johannes Reitsma Karel Moons Joris de Groot Chris Hyde Jaime Peters Bogdan Grigore Jaime Peters Chris Hyde Chris Hyde Obi Ukoumunne Jaime Peters Zhivko Zhelev Brooke Levis Andrea Benedetti Alexander W Levis John P A Ioannidis Ian Shrier Pim Cuijpers Simon Gilbody Lorie A Kloda Dean McMillan Scott B Patten Russell J Steele Roy C Ziegelstein Charles H Bombardier Flavia de Lima Osório Jesse R Fann Dwenda Gjerdingen Femke Lamers Manote Lotrakul Sonia R Loureiro Bernd Löwe Juwita Shaaban Lesley Stafford Henk C P M van Weert Mary A Whooley Linda S Williams Karin A Wittkampf Albert S Yeung Brett D Thombs Jaime Peters Chris Cooper James Buchanan Tom Nieto Claire Smith Olga Tucker Janine Dretzke Andrew Beggs Nirmala Rai Clare Davenport Sue Bayliss Simon Stevens Kym Snell Sue Mallet Jon Deeks Sudha Sundar Emma Hall Nuria Porta David Lorente Estelles Johann de Bono

Diagn Progn Res 2017 30;1:11. Epub 2017 Mar 30.

278The Institute of Cancer Research, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s41512-017-0011-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460744PMC
March 2017

Systemic Immunomodulating Therapies for Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Systematic Review and Meta-analysis.

JAMA Dermatol 2017 06;153(6):514-522

Dokumentationszentrum schwerer Hautreaktionen, Department of Dermatology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamadermatol.2016.5668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817620PMC
June 2017

Survival biases lead to flawed conclusions in observational treatment studies of influenza patients.

J Clin Epidemiol 2017 Apr 7;84:121-129. Epub 2017 Feb 7.

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center-University of Freiburg, Stefan-Meier-Str. 26, 79104 Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jclinepi.2017.01.008DOI Listing
April 2017

Norman Edward Breslow-Key figure in the foundation of modern biostatistics.

Biom J 2017 05 27;59(3):399-404. Epub 2017 Jan 27.

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, 79104, Germany.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/bimj.201600196
Publisher Site
http://dx.doi.org/10.1002/bimj.201600196DOI Listing
May 2017

Interleukin-15 Is Associated with Severity and Mortality in Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis.

J Invest Dermatol 2017 May 21;137(5):1065-1073. Epub 2016 Dec 21.

Whole-Genome Research Core Laboratory of Human Diseases, Chang Gung Memorial Hospital, Keelung, Taiwan; Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Taipei, Linkou and Keelung, Taiwan; Chang Gung Immunology Consortium, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan; Department of Dermatology, Xiamen Chang Gung Hospital, Xiamen, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jid.2016.11.034DOI Listing
May 2017

Discussion of "A risk-based measure of time-varying prognostic discrimination for survival models," by C. Jason Liang and Patrick J. Heagerty.

Biometrics 2017 09 8;73(3):739-741. Epub 2016 Dec 8.

Institute for Medical Biometry and Statistics, Medical Center, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/biom.12629DOI Listing
September 2017

Estimating hazard ratios in cohort data with missing disease information due to death.

Biom J 2017 Mar 21;59(2):251-269. Epub 2016 Nov 21.

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Stefan-Meier-Str. 26, 79104, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bimj.201500167DOI Listing
March 2017

RE: "COMPARISON OF STATISTICAL APPROACHES FOR DEALING WITH IMMORTAL TIME BIAS IN DRUG EFFECTIVENESS STUDIES".

Am J Epidemiol 2016 12 16;184(11):856-858. Epub 2016 Nov 16.

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/aje/kww156DOI Listing
December 2016

A case-cohort approach for multi-state models in hospital epidemiology.

Stat Med 2017 02 24;36(3):481-495. Epub 2016 Oct 24.

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/sim.7146DOI Listing
February 2017

Multiple time scales in modeling the incidence of infections acquired in intensive care units.

BMC Med Res Methodol 2016 09 1;16(1):116. Epub 2016 Sep 1.

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12874-016-0199-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009530PMC
September 2016

Neuraminidase Inhibitors and Hospital Mortality in British Patients with H1N1 Influenza A: A Re-Analysis of Observational Data.

PLoS One 2016 1;11(9):e0160430. Epub 2016 Sep 1.

Center for Medical Biometry and Medical Informatics, Institute for Medical Biometry and Statistics, Medical Center University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160430PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008789PMC
August 2017

Integrating multiple molecular sources into a clinical risk prediction signature by extracting complementary information.

BMC Bioinformatics 2016 Aug 30;17(1):327. Epub 2016 Aug 30.

Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center Johannes Gutenberg University Mainz, Obere Zahlbacher Str. 69, Mainz, 55131, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12859-016-1183-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004308PMC
August 2016

The case-crossover design via penalized regression.

BMC Med Res Methodol 2016 08 22;16:103. Epub 2016 Aug 22.

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12874-016-0197-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994302PMC
August 2016

Modelling multiple thresholds in meta-analysis of diagnostic test accuracy studies.

BMC Med Res Methodol 2016 08 12;16(1):97. Epub 2016 Aug 12.

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Stefan-Meier-Strasse 2679104, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12874-016-0196-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983029PMC
August 2016

Competing risk bias was common in a prominent medical journal.

J Clin Epidemiol 2016 12 1;80:135-136. Epub 2016 Aug 1.

Institute of Statistics, Ulm University, Helmholtzstr. 20, 89081 Ulm, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jclinepi.2016.07.013DOI Listing
December 2016

Geriatric assessment in multiple myeloma patients: validation of the International Myeloma Working Group (IMWG) score and comparison with other common comorbidity scores.

Haematologica 2016 09 16;101(9):1110-9. Epub 2016 Jun 16.

Department of Medicine I, Hematology, Oncology & Stem Cell Transplantation, Medical Center, Faculty of Medicine, University of Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3324/haematol.2016.148189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5060028PMC
September 2016

Incidence of Dementia over Three Decades in the Framingham Heart Study.

N Engl J Med 2016 07;375(1):92-3

University of Freiburg Medical Center, Freiburg, Germany

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMc1604823DOI Listing
July 2016

Adverse event development in clinical oncology trials.

Lancet Oncol 2016 07;17(7):e263-e264

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1470-2045(16)30223-6DOI Listing
July 2016

Analysing adverse events by time-to-event models: the CLEOPATRA study.

Pharm Stat 2016 Jul 16;15(4):306-14. Epub 2016 Jun 16.

Institute for Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/pst.1758
Publisher Site
http://dx.doi.org/10.1002/pst.1758DOI Listing
July 2016

Identifying Prognostic SNPs in Clinical Cohorts: Complementing Univariate Analyses by Resampling and Multivariable Modeling.

PLoS One 2016 9;11(5):e0155226. Epub 2016 May 9.

Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center Johannes Gutenberg University Mainz, Mainz, Germany.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0155226PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861340PMC
July 2017

Soluble Urokinase Receptor and Chronic Kidney Disease.

N Engl J Med 2016 03;374(9):890

University of Ulm, Ulm, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMc1515787DOI Listing
March 2016

Improving the Prognostic Ability through Better Use of Standard Clinical Data - The Nottingham Prognostic Index as an Example.

PLoS One 2016 3;11(3):e0149977. Epub 2016 Mar 3.

Universitätsklinikum Freiburg, Institut für Medizinische Biometrie und Statistik, Department für Medizinische Biometrie und Medizinische Informatik, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0149977PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4777365PMC
July 2016

A full competing risk analysis of hospital-acquired infections can easily be performed by a case-cohort approach.

J Clin Epidemiol 2016 06 26;74:187-93. Epub 2015 Nov 26.

Institute for Medical Biometry and Statistics, Center for Medical Biometry and Medical Informatics, Medical Center University of Freiburg, Stefan-Meier-Str. 26, 79104 Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jclinepi.2015.11.011DOI Listing
June 2016

Meta-analysis for aggregated survival data with competing risks: a parametric approach using cumulative incidence functions.

Res Synth Methods 2016 Sep 20;7(3):282-93. Epub 2015 Sep 20.

Institute of Medical Biometry and Statistics - Medical Center, University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jrsm.1165DOI Listing
September 2016

Predictors of prognosis and treatment outcome in central retinal artery occlusion: local intra-arterial fibrinolysis vs. conservative treatment.

Neuroradiology 2015 Oct 8;57(10):1055-62. Epub 2015 Sep 8.

University Hospital Göttingen, University Eye Hospital, Göttingen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00234-015-1588-3DOI Listing
October 2015

Outcome after BCG treatment for urinary bladder cancer may be influenced by polymorphisms in the NOS2 and NOS3 genes.

Redox Biol 2015 Dec 10;6:272-277. Epub 2015 Aug 10.

Urology Laboratory, Department of Molecular Medicine and Surgery, Karolinska Institutet, 171 76 Stockholm, Sweden; Department of Urology, Karolinska University Hospital, 171 76 Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.redox.2015.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556773PMC
December 2015

Pilot study of adoptive immunotherapy with sentinel node-derived T cells in muscle-invasive urinary bladder cancer.

Scand J Urol 2015 Dec 4;49(6):453-462. Epub 2015 Jul 4.

f 6 Translational Immunology Unit, Department of Medicine, Karolinska University Hospital, Karolinska Institutet , Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/21681805.2015.1059880DOI Listing
December 2015

Analysis of survival by tumor response: have we learnt any better?

Ann Hematol 2015 Sep 24;94(9):1615-6. Epub 2015 Jun 24.

Center of Clinical Trials, University Medical Center Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00277-015-2426-8DOI Listing
September 2015

From hypertension control to global cardiovascular risk management: an educational intervention in a cluster-randomised controlled trial.

BMC Fam Pract 2015 May 7;16:56. Epub 2015 May 7.

Institute of General Medicine, Medical Faculty, Heinrich-Heine-University Düsseldorf, P.O. Box 101001, 40225, Düsseldorf, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12875-015-0274-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426642PMC
May 2015

Conditional Survival: A Useful Concept to Provide Information on How Prognosis Evolves over Time.

Clin Cancer Res 2015 Apr;21(7):1530-6

Institute for Medical Biometry and Statistics, Medical Center, University of Freiburg, Freiburg im Breisgau, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-14-2154DOI Listing
April 2015