Martin Schlee

Martin Schlee

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Martin Schlee

Martin Schlee

Publications by authors named "Martin Schlee"

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43Publications

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G-rich DNA-induced stress response blocks type-I-IFN but not CXCL10 secretion in monocytes.

Sci Rep 2016 12 12;6:38405. Epub 2016 Dec 12.

Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.

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http://dx.doi.org/10.1038/srep38405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5150577PMC
December 2016

Discriminating self from non-self in nucleic acid sensing.

Nat Rev Immunol 2016 09 25;16(9):566-80. Epub 2016 Jul 25.

Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital, University of Bonn, Sigmund-Freud-Strasse 25, D-53127 Bonn, Germany.

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http://dx.doi.org/10.1038/nri.2016.78DOI Listing
September 2016

Enzymatic synthesis and purification of a defined RIG-I ligand.

Methods Mol Biol 2014 ;1169:15-25

Institute for Clinical Chemistry and Clinical Pharmacology, University Hospital, University of Bonn, Sigmund-Freud-Strasse 25, 53127, Bonn, Germany.

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http://dx.doi.org/10.1007/978-1-4939-0882-0_2DOI Listing
February 2015

Master sensors of pathogenic RNA - RIG-I like receptors.

Authors:
Martin Schlee

Immunobiology 2013 Nov 1;218(11):1322-35. Epub 2013 Jul 1.

Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, 53105 Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.imbio.2013.06.007DOI Listing
November 2013

Exosomes as nucleic acid nanocarriers.

Adv Drug Deliv Rev 2013 Mar 28;65(3):331-5. Epub 2012 Jun 28.

Institute for Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.

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http://dx.doi.org/10.1016/j.addr.2012.06.011DOI Listing
March 2013

SiRNA delivery with exosome nanoparticles.

Nat Biotechnol 2011 Apr;29(4):325-6

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http://dx.doi.org/10.1038/nbt.1830DOI Listing
April 2011

Monocyte-mediated inhibition of TLR9-dependent IFN-α induction in plasmacytoid dendritic cells questions bacterial DNA as the active ingredient of bacterial lysates.

J Immunol 2010 Dec 5;185(12):7367-73. Epub 2010 Nov 5.

Institute of Clinical Chemistry and Clinical Pharmacology, Rheinische Friedrich-Wilhelms University Bonn, Bonn, Germany.

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http://dx.doi.org/10.4049/jimmunol.1001798DOI Listing
December 2010

The chase for the RIG-I ligand--recent advances.

Mol Ther 2010 Jul 11;18(7):1254-62. Epub 2010 May 11.

Institute of Clinical Chemistry and Pharmacology, University Hospital Bonn, Bonn, Germany.

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http://dx.doi.org/10.1038/mt.2010.90DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911265PMC
July 2010

c-MYC impairs immunogenicity of human B cells.

Adv Cancer Res 2007 ;97:167-88

Institute of Clinical Molecular Biology and Tumor Genetics, GSF-National Research Center for Environment and Health, D-81377 München, Germany.

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http://dx.doi.org/10.1016/S0065-230X(06)97007-9DOI Listing
October 2009

c-Myc and Rel/NF-kappaB are the two master transcriptional systems activated in the latency III program of Epstein-Barr virus-immortalized B cells.

J Virol 2009 May 4;83(10):5014-27. Epub 2009 Mar 4.

Centre National de la Recherche Scientifique, Unité Mixte de Recherche 6101, Centre Hospitalier Universitaire Dupuytren, Université de Limoges, Laboratoire d'Hématologie, 87025 Limoges, France.

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http://dx.doi.org/10.1128/JVI.02264-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682111PMC
May 2009

Selective and direct activation of human neutrophils but not eosinophils by Toll-like receptor 8.

J Allergy Clin Immunol 2009 May 10;123(5):1026-33. Epub 2009 Apr 10.

Institute of Clinical Chemistry and Pharmacology, University Hospital, University of Bonn, Bonn, Germany.

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http://dx.doi.org/10.1016/j.jaci.2009.02.015DOI Listing
May 2009

Approaching the RNA ligand for RIG-I?

Immunol Rev 2009 Jan;227(1):66-74

Institute of Clinical Chemistry and Pharmacology, University Hospital Bonn, Bonn, Germany.

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http://dx.doi.org/10.1111/j.1600-065X.2008.00724.xDOI Listing
January 2009

Accessing the therapeutic potential of immunostimulatory nucleic acids.

Curr Opin Immunol 2008 Aug 30;20(4):389-95. Epub 2008 Jul 30.

Institute for Clinical Chemistry and Pharmacology, University Hospital, University of Bonn, Sigmund-Freud-Str. 25, Bonn, Germany.

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http://dx.doi.org/10.1016/j.coi.2008.07.007DOI Listing
August 2008

RNA recognition via TLR7 and TLR8.

Handb Exp Pharmacol 2008 (183):71-86

Institute of Clinical Biochemistry and Pharmacology, University Hospital , University of Bonn, Germany.

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http://dx.doi.org/10.1007/978-3-540-72167-3_4DOI Listing
February 2008

5'-Triphosphate RNA is the ligand for RIG-I.

Science 2006 Nov 12;314(5801):994-7. Epub 2006 Oct 12.

Division of Clinical Pharmacology, Department of Internal Medicine, University of Munich, 80336 Munich, Germany.

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http://dx.doi.org/10.1126/science.1132505DOI Listing
November 2006

siRNA and isRNA: two edges of one sword.

Mol Ther 2006 Oct 31;14(4):463-70. Epub 2006 Jul 31.

Division of Clinical Pharmacology, Department of Medicine, University of Bonn, Sigmund-Freud-Strasse 25, 53127 Bonn, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S152500160600217
Publisher Site
http://dx.doi.org/10.1016/j.ymthe.2006.06.001DOI Listing
October 2006

MDM2 is recognized as a tumor-associated antigen in chronic lymphocytic leukemia by CD8+ autologous T lymphocytes.

Exp Hematol 2006 Jan;34(1):44-53

KKG Gene Therapy, GSF-National Research Center for Environment and Health, Munich, Germany.

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http://dx.doi.org/10.1016/j.exphem.2005.09.016DOI Listing
January 2006

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7.

Nat Med 2005 Mar 20;11(3):263-70. Epub 2005 Feb 20.

Department of Internal Medicine, Division of Clinical Pharmacology, Ludwig-Maximilians-University of Munich, Ziemssenstr. 1, 80336 München, Germany.

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http://www.nature.com/articles/nm1191
Publisher Site
http://dx.doi.org/10.1038/nm1191DOI Listing
March 2005

Active NF-kappaB signalling is a prerequisite for influenza virus infection.

J Gen Virol 2004 Aug;85(Pt 8):2347-56

Klinische Kooperationsgruppe, Pädiatrische Tumorimmunologie, Kinderklinik, Universitätsklinikum der Technischen Universität München, Marchioninistr. 25, D-81377 München, Germany.

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http://dx.doi.org/10.1099/vir.0.79958-0DOI Listing
August 2004