Martin R Turner

Martin R Turner

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Martin R Turner

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Therapeutic non-invasive brain stimulation in amyotrophic lateral sclerosis: rationale, methods and experience.

J Neurol Neurosurg Psychiatry 2019 Oct 9;90(10):1131-1138. Epub 2019 May 9.

Nuffield Department of Clinical Neurosciences, Oxford University, Oxford, UK

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http://jnnp.bmj.com/lookup/doi/10.1136/jnnp-2018-320213
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http://dx.doi.org/10.1136/jnnp-2018-320213DOI Listing
October 2019

Defining pre-symptomatic amyotrophic lateral sclerosis.

Amyotroph Lateral Scler Frontotemporal Degener 2019 Aug 20;20(5-6):303-309. Epub 2019 Mar 20.

a Department of Neurology , University of Miami , Miami , FL , USA and.

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http://dx.doi.org/10.1080/21678421.2019.1587634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613999PMC
August 2019

Relative preservation of triceps over biceps strength in upper limb-onset ALS: the 'split elbow'.

J Neurol Neurosurg Psychiatry 2019 Jul 7;90(7):730-733. Epub 2019 Mar 7.

Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, King's College London, London, UK

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http://dx.doi.org/10.1136/jnnp-2018-319894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585260PMC
July 2019

Tracheostomy in motor neurone disease.

Pract Neurol 2019 Jul 4. Epub 2019 Jul 4.

Nuffield Department of Clinical Neurosciences, Oxford University, Oxford, UK.

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http://dx.doi.org/10.1136/practneurol-2018-002109DOI Listing
July 2019

Untangling neuroinflammation in amyotrophic lateral sclerosis.

J Neurol Neurosurg Psychiatry 2019 Jul 11. Epub 2019 Jul 11.

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/jnnp-2019-321242DOI Listing
July 2019

Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis.

JAMA Neurol 2019 Jun 17. Epub 2019 Jun 17.

UCL Institute of Neurology, Queen Square, London, United Kingdom.

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http://dx.doi.org/10.1001/jamaneurol.2019.1534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580449PMC
June 2019

The early biomarker challenge in neurodegenerative disorders.

Authors:
Martin R Turner

J Neurol Neurosurg Psychiatry 2019 Jun 26. Epub 2019 Jun 26.

Nuffield Department of Clinical Neurosciences, Oxford University, Oxford, UK

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http://dx.doi.org/10.1136/jnnp-2019-321145DOI Listing
June 2019

Human cerebral evolution and the clinical syndrome of amyotrophic lateral sclerosis.

J Neurol Neurosurg Psychiatry 2019 May 17;90(5):570-575. Epub 2018 Apr 17.

Division of Neurology Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1136/jnnp-2017-317245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581076PMC
May 2019

Cerebellar tract alterations in PLS and ALS.

Amyotroph Lateral Scler Frontotemporal Degener 2019 May 21;20(3-4):281-284. Epub 2019 Jan 21.

b Wellcome Centre for Integrative Neuroimaging , University of Oxford , Oxford , UK.

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https://www.tandfonline.com/doi/full/10.1080/21678421.2018.1
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http://dx.doi.org/10.1080/21678421.2018.1562554DOI Listing
May 2019

MND Plus.

Authors:
Martin R Turner

Pract Neurol 2019 May 21. Epub 2019 May 21.

Nuffield Department of Clinical Neurosciences, Oxford University, Oxford, UK

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http://dx.doi.org/10.1136/practneurol-2019-002213DOI Listing
May 2019

CSF chitinase proteins in amyotrophic lateral sclerosis.

J Neurol Neurosurg Psychiatry 2019 May 23. Epub 2019 May 23.

Nuffield Department of Clinical Neurosciences, Oxford University, Oxford, UK

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http://dx.doi.org/10.1136/jnnp-2019-320442DOI Listing
May 2019

Revised Airlie House consensus guidelines for design and implementation of ALS clinical trials.

Neurology 2019 Apr 8;92(14):e1610-e1623. Epub 2019 Mar 8.

From the Department of Neurology (L.H.v.d.B.), Brain Center Rudolf Magnus, University Medical Center Utrecht, the Netherlands; Department of Neurology (E.S.), Mayo Clinic, Rochester, MN; Department of Neurology (G.G.), University of Kansas Medical Center, Kansas City; Department of Medicine (E.A.M.), Massachusetts General Hospital, Biostatistics Center, Harvard Medical School, Boston; Department of Neurology (J.A., H.M.), Columbia University, Eleanor and Lou Gehrig ALS Center, New York, NY; Department of Neurology (R.H.B.), Cedars-Sinai Medical Center, Los Angeles, CA; Department of Neurology (M.B.), University of Miami, FL; Neurological Clinical Research Institute (J.D.B.), Massachusetts General Hospital, Boston; Rita Levi Montalcini Department of Neuroscience (A.C.), University of Torino, Italy; Centre Constitutif SLA (P.C.), Université de Tours, France; Department of Neurology (A.G.), Clinical Research Unit, Montreal Neurological Institute, Neurosurgery, McGill University, Montreal, Canada; National Institute of Neurological Disorders and Stroke (A.K.G.), National Institutes of Health, Bethesda, MD; ALS Center (C.L.-H.), University of California San Francisco; Department of Neuroscience (C.J.M.), Sheffield Institute for Translational Neuroscience, University of Sheffield, UK; Department of Neurology (E.P.P.), Section of ALS & Related Disorders, Cleveland Clinic, OH; Department of Neurology (J.R.), The Center for Restorative Neurology, Loma Linda University School of Medicine, CA; Department of Neurology and Laboratory of Neuroscience (V.S.), Istituto Auxologico Italiano, IRCCS, Milan; Department of Pathophysiology and Transplantation (V.S.), "Dino Ferrari" Centre, Università degli Studi di Milano, Milan, Italy; Nuffield Department of Clinical Neurosciences (M.R.T.), University of Oxford, UK; Neuromuscular Diseases Unit/ALS Clinic (M.W.), Kantonsspital St. Gallen, Switzerland; Carolinas Neuromuscular/ALS-MDA Care Center (B.R.B.), Charlotte; Department of Neurology (B.R.B.), Carolinas Medical Center, University of North Carolina School of Medicine, Charlotte; Forbes Norris ALS Treatment and Research Center (R.G.M.), California Pacific Medical Center San Francisco; and Department of Neurosciences (R.G.M.), Stanford University, CA.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000007242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448453PMC
April 2019

The reunification of amyotrophic lateral sclerosis.

Authors:
Martin R Turner

J Neurol Neurosurg Psychiatry 2019 Feb 8;90(2):122-123. Epub 2018 Oct 8.

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford OX3 9DU, UK

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http://jnnp.bmj.com/lookup/doi/10.1136/jnnp-2018-319470
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http://dx.doi.org/10.1136/jnnp-2018-319470DOI Listing
February 2019

Imaging Cerebral Activity in Amyotrophic Lateral Sclerosis.

Front Neurol 2018 8;9:1148. Epub 2019 Jan 8.

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.

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https://www.frontiersin.org/article/10.3389/fneur.2018.01148
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http://dx.doi.org/10.3389/fneur.2018.01148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332509PMC
January 2019

Regional thalamic MRI as a marker of widespread cortical pathology and progressive frontotemporal involvement in amyotrophic lateral sclerosis.

J Neurol Neurosurg Psychiatry 2018 Dec 26;89(12):1250-1258. Epub 2018 Jul 26.

Wellcome Centre for Integrative Neuroimaging, University of Oxford, Oxford, UK

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http://dx.doi.org/10.1136/jnnp-2018-318625DOI Listing
December 2018

UFLC-Derived CSF Extracellular Vesicle Origin and Proteome.

Proteomics 2018 12 10;18(24):e1800257. Epub 2018 Dec 10.

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.

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http://doi.wiley.com/10.1002/pmic.201800257
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http://dx.doi.org/10.1002/pmic.201800257DOI Listing
December 2018

Towards a TDP-43-Based Biomarker for ALS and FTLD.

Mol Neurobiol 2018 Oct 19;55(10):7789-7801. Epub 2018 Feb 19.

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1007/s12035-018-0947-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132775PMC
October 2018

Amyotrophic lateral sclerosis: the complex path to precision medicine.

J Neurol 2018 Oct 27;265(10):2454-2462. Epub 2018 Jul 27.

Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, OX3 9DU, UK.

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http://dx.doi.org/10.1007/s00415-018-8983-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182683PMC
October 2018

Impaired corticomuscular and interhemispheric cortical beta oscillation coupling in amyotrophic lateral sclerosis.

Clin Neurophysiol 2018 07 6;129(7):1479-1489. Epub 2018 Apr 6.

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK; Oxford Centre for Human Brain Activity, University of Oxford, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/j.clinph.2018.03.019DOI Listing
July 2018

Progress and new frontiers in biomarkers for amyotrophic lateral sclerosis.

Authors:
Martin R Turner

Biomark Med 2018 07 1;12(7):693-696. Epub 2018 Jun 1.

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

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https://www.futuremedicine.com/doi/10.2217/bmm-2018-0149
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http://dx.doi.org/10.2217/bmm-2018-0149DOI Listing
July 2018

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry.

World J Biol Psychiatry 2018 06 27;19(4):244-328. Epub 2017 Oct 27.

a Department of Psychiatry and Psychotherapy , Universitätsklinikum Erlangen, and Friedrich-Alexander Universität Erlangen-Nürnberg , Erlangen , Germany.

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http://dx.doi.org/10.1080/15622975.2017.1375556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916324PMC
June 2018

Kinnier Wilson's puzzling features of amyotrophic lateral sclerosis.

J Neurol Neurosurg Psychiatry 2018 Jun 9;89(6):657-666. Epub 2017 Nov 9.

The Royal London Hospital, London, UK.

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http://dx.doi.org/10.1136/jnnp-2017-317217DOI Listing
June 2018

Increased cerebral functional connectivity in ALS: A resting-state magnetoencephalography study.

Neurology 2018 04 21;90(16):e1418-e1424. Epub 2018 Mar 21.

From the Nuffield Department of Clinical Neurosciences (M.P., K.T., M.R.T.), and Oxford Centre for Human Brain Activity (M.P., G.L.C., A.Q., A.C.N., M.W.W., M.R.T.), University of Oxford, UK; and Miller School of Medicine (J.W., M.B.), University of Miami, FL.

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http://dx.doi.org/10.1212/WNL.0000000000005333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902786PMC
April 2018

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

Authors:
Aude Nicolas Kevin P Kenna Alan E Renton Nicola Ticozzi Faraz Faghri Ruth Chia Janice A Dominov Brendan J Kenna Mike A Nalls Pamela Keagle Alberto M Rivera Wouter van Rheenen Natalie A Murphy Joke J F A van Vugt Joshua T Geiger Rick A Van der Spek Hannah A Pliner Shankaracharya Bradley N Smith Giuseppe Marangi Simon D Topp Yevgeniya Abramzon Athina Soragia Gkazi John D Eicher Aoife Kenna Gabriele Mora Andrea Calvo Letizia Mazzini Nilo Riva Jessica Mandrioli Claudia Caponnetto Stefania Battistini Paolo Volanti Vincenzo La Bella Francesca L Conforti Giuseppe Borghero Sonia Messina Isabella L Simone Francesca Trojsi Fabrizio Salvi Francesco O Logullo Sandra D'Alfonso Lucia Corrado Margherita Capasso Luigi Ferrucci Cristiane de Araujo Martins Moreno Sitharthan Kamalakaran David B Goldstein Aaron D Gitler Tim Harris Richard M Myers Hemali Phatnani Rajeeva Lochan Musunuri Uday Shankar Evani Avinash Abhyankar Michael C Zody Julia Kaye Steven Finkbeiner Stacia K Wyman Alex LeNail Leandro Lima Ernest Fraenkel Clive N Svendsen Leslie M Thompson Jennifer E Van Eyk James D Berry Timothy M Miller Stephen J Kolb Merit Cudkowicz Emily Baxi Michael Benatar J Paul Taylor Evadnie Rampersaud Gang Wu Joanne Wuu Giuseppe Lauria Federico Verde Isabella Fogh Cinzia Tiloca Giacomo P Comi Gianni Sorarù Cristina Cereda Philippe Corcia Hannu Laaksovirta Liisa Myllykangas Lilja Jansson Miko Valori John Ealing Hisham Hamdalla Sara Rollinson Stuart Pickering-Brown Richard W Orrell Katie C Sidle Andrea Malaspina John Hardy Andrew B Singleton Janel O Johnson Sampath Arepalli Peter C Sapp Diane McKenna-Yasek Meraida Polak Seneshaw Asress Safa Al-Sarraj Andrew King Claire Troakes Caroline Vance Jacqueline de Belleroche Frank Baas Anneloor L M A Ten Asbroek José Luis Muñoz-Blanco Dena G Hernandez Jinhui Ding J Raphael Gibbs Sonja W Scholz Mary Kay Floeter Roy H Campbell Francesco Landi Robert Bowser Stefan M Pulst John M Ravits Daniel J L MacGowan Janine Kirby Erik P Pioro Roger Pamphlett James Broach Glenn Gerhard Travis L Dunckley Christopher B Brady Neil W Kowall Juan C Troncoso Isabelle Le Ber Kevin Mouzat Serge Lumbroso Terry D Heiman-Patterson Freya Kamel Ludo Van Den Bosch Robert H Baloh Tim M Strom Thomas Meitinger Aleksey Shatunov Kristel R Van Eijk Mamede de Carvalho Maarten Kooyman Bas Middelkoop Matthieu Moisse Russell L McLaughlin Michael A Van Es Markus Weber Kevin B Boylan Marka Van Blitterswijk Rosa Rademakers Karen E Morrison A Nazli Basak Jesús S Mora Vivian E Drory Pamela J Shaw Martin R Turner Kevin Talbot Orla Hardiman Kelly L Williams Jennifer A Fifita Garth A Nicholson Ian P Blair Guy A Rouleau Jesús Esteban-Pérez Alberto García-Redondo Ammar Al-Chalabi Ekaterina Rogaeva Lorne Zinman Lyle W Ostrow Nicholas J Maragakis Jeffrey D Rothstein Zachary Simmons Johnathan Cooper-Knock Alexis Brice Stephen A Goutman Eva L Feldman Summer B Gibson Franco Taroni Antonia Ratti Cinzia Gellera Philip Van Damme Wim Robberecht Pietro Fratta Mario Sabatelli Christian Lunetta Albert C Ludolph Peter M Andersen Jochen H Weishaupt William Camu John Q Trojanowski Vivianna M Van Deerlin Robert H Brown Leonard H van den Berg Jan H Veldink Matthew B Harms Jonathan D Glass David J Stone Pentti Tienari Vincenzo Silani Adriano Chiò Christopher E Shaw Bryan J Traynor John E Landers

Neuron 2018 03;97(6):1268-1283.e6

Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867896PMC
March 2018

Cerebrospinal fluid macrophage biomarkers in amyotrophic lateral sclerosis.

Ann Neurol 2018 02 9;83(2):258-268. Epub 2018 Feb 9.

Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom.

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http://dx.doi.org/10.1002/ana.25143DOI Listing
February 2018

Non-invasive in vivo neuropathology of the -related ALS-FTD syndrome.

Authors:
Martin R Turner

J Neurol Neurosurg Psychiatry 2018 01 20;89(1):4-5. Epub 2017 Oct 20.

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http://dx.doi.org/10.1136/jnnp-2017-317010DOI Listing
January 2018

Multicenter evaluation of neurofilaments in early symptom onset amyotrophic lateral sclerosis.

Neurology 2018 01 6;90(1):e22-e30. Epub 2017 Dec 6.

From the Nuffield Department of Clinical Neurosciences (E.F., E.G., M.R.T.), University of Oxford, UK; Department of Neurology (P.O., P.S., F.V., J.H.W., P.W., A.C.L., M.O.), Ulm University Hospital, Germany; Department of Pathophysiology and Transplantation (F.V., V.S.), Università degli Studi di Milano; Department of Neurology-Stroke Unit and Laboratory of Neuroscience (F.V., C.M., V.S.), IRCCS Istituto Auxologico Italiano, Milan, Italy; Neurologic Clinic and Policlinic, Departments of Medicine, Clinical Research, and Biomedicine (C.B., J.K.), University Hospital and University of Basel, Switzerland; Department of Neurology (P.V.D.) and Laboratory of Molecular Neurobiomarker Research and Laboratory Medicine (K.P.), University Hospitals Leuven; KU Leuven-University of Leuven (P.V.D.); Department of Neurosciences (P.V.D.), VIB-Center for Brain & Disease Research, Leuven, Belgium; Department of Neurology (J.G., P.M., B.S.), Jena University Hospital, Germany; Department of Metabolic Biochemistry (C.J., F.L.) and Neurological Diseases Department (M.d.M.A., F.S.), Hôpitaux Universitaires Pitié Salpêtrière-Charles Foix, Paris, France; Department of Neurology (S.K., S.P.), Hannover Medical School; Institute for Epidemiology and Medical Biometry (B.M.) Ulm University, Germany; Donders Institute for Brain, Cognition and Behaviour, Department of Neurology (J.R., M.M.V.), and Radboud Alzheimer Center, Department of Laboratory Medicine (M.M.V.), Radboud University Medical Center, Nijmegen, the Netherlands; and Department of Neurodegenerative Disease and Gerontopsychiatry/Neurology (P.W.), Bonn University Hospital, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000004761DOI Listing
January 2018

Genetic screening in sporadic ALS and FTD.

J Neurol Neurosurg Psychiatry 2017 12 22;88(12):1042-1044. Epub 2017 Jun 22.

Nuffield Department of Clinical Neurosciences, Oxford University, Oxford, UK.

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http://dx.doi.org/10.1136/jnnp-2017-315995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740553PMC
December 2017

The benefit of evolving multidisciplinary care in ALS: a diagnostic cohort survival comparison.

Amyotroph Lateral Scler Frontotemporal Degener 2017 11 18;18(7-8):569-575. Epub 2017 Jul 18.

a Department of Basic and Clinical Neuroscience , Institute of Psychiatry, Psychology and Neuroscience, Maurice Wohl Clinical Neuroscience Institute, King's College London , London , UK.

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http://dx.doi.org/10.1080/21678421.2017.1349151DOI Listing
November 2017

The ALSFRS as an outcome measure in therapeutic trials and its relationship to symptom onset.

Amyotroph Lateral Scler Frontotemporal Degener 2016 Jul-Aug;17(5-6):414-25. Epub 2016 Feb 11.

a Nuffield Department of Clinical Neuroscience , University of Oxford and.

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http://dx.doi.org/10.3109/21678421.2016.1140786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950444PMC
October 2017

Analysis of terms used for the diagnosis and classification of amyotrophic lateral sclerosis and motor neuron disease.

Amyotroph Lateral Scler Frontotemporal Degener 2016 Oct - Nov;17(7-8):600-604. Epub 2016 May 18.

a Department of Basic and Clinical Neuroscience , Maurice Wohl Clinical Neuroscience Institute, King's College London , London, UK.

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http://dx.doi.org/10.1080/21678421.2016.1181766DOI Listing
October 2017

Quantitative FLAIR MRI in Amyotrophic Lateral Sclerosis.

Acad Radiol 2017 10 29;24(10):1187-1194. Epub 2017 May 29.

Centre for Functional Magnetic Resonance Imaging of the Brain, Oxford University, John Radcliffe Hospital, West Wing Level 6, Oxford OX3 9DU, UK; Nuffield Department of Clinical Neurosciences, Oxford University, John Radcliffe Hospital, West Wing Level 6, Oxford OX3 9DU, UK; Oxford University Centre for Magnetic Resonance Research, John Radcliffe Hospital, West Wing Level 6, Oxford OX3 9DU, UK. Electronic address:

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http://dx.doi.org/10.1016/j.acra.2017.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605225PMC
October 2017

Focal precentral gyrus involvement in osmotic demyelination.

Pract Neurol 2017 Oct 19;17(5):410-411. Epub 2017 Aug 19.

Department of Neurology, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, Oxfordshire, UK.

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http://dx.doi.org/10.1136/practneurol-2017-001682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629936PMC
October 2017

Is cardiovascular fitness a risk factor for ALS?

Authors:
Martin R Turner

J Neurol Neurosurg Psychiatry 2017 07 14;88(7):538. Epub 2017 Mar 14.

Nuffield Department of Clinical Neurosciences, Oxford University, Oxford, UK.

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http://dx.doi.org/10.1136/jnnp-2017-315606DOI Listing
July 2017

The tough body at the epicentre of amyotrophic lateral sclerosis.

J Neurol Neurosurg Psychiatry 2017 05 13;88(5):369-370. Epub 2016 Dec 13.

Nuffield Department of Clinical Neurosciences, Oxford University, Oxford, UK.

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http://dx.doi.org/10.1136/jnnp-2016-315247DOI Listing
May 2017

Amyotrophic lateral sclerosis - frontotemporal spectrum disorder (ALS-FTSD): Revised diagnostic criteria.

Amyotroph Lateral Scler Frontotemporal Degener 2017 05 5;18(3-4):153-174. Epub 2017 Jan 5.

n Nuffield Department of Clinical Neurosciences , University of Oxford , Oxford , UK.

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http://dx.doi.org/10.1080/21678421.2016.1267768DOI Listing
May 2017

A risk stratifying tool to facilitate safe late-stage percutaneous endoscopic gastrostomy in ALS.

Amyotroph Lateral Scler Frontotemporal Degener 2017 05 19;18(3-4):243-248. Epub 2017 Jan 19.

a Nuffield Department of Clinical Neurosciences , University of Oxford , Oxford , UK.

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http://dx.doi.org/10.1080/21678421.2016.1274330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425625PMC
May 2017

Sweet food preference in amyotrophic lateral sclerosis.

Pract Neurol 2017 Apr 10;17(2):128-129. Epub 2017 Jan 10.

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/practneurol-2016-001554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520252PMC
April 2017

A multicentre evaluation of oropharyngeal secretion management practices in amyotrophic lateral sclerosis.

Amyotroph Lateral Scler Frontotemporal Degener 2017 02 31;18(1-2):1-9. Epub 2016 Aug 31.

a Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield, & Academic Directorate of Neurosciences, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust , Sheffield.

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http://dx.doi.org/10.1080/21678421.2016.1221433DOI Listing
February 2017

Neuroimaging Endpoints in Amyotrophic Lateral Sclerosis.

Neurotherapeutics 2017 01;14(1):11-23

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

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http://link.springer.com/10.1007/s13311-016-0484-9
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http://dx.doi.org/10.1007/s13311-016-0484-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233627PMC
January 2017

Psychiatric disorders prior to amyotrophic lateral sclerosis.

Ann Neurol 2016 12 14;80(6):935-938. Epub 2016 Nov 14.

Oxford University Nuffield Department of Population Health, Old Road Campus, Oxford, United Kingdom.

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http://dx.doi.org/10.1002/ana.24801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215396PMC
December 2016

Motor neuron disease: biomarker development for an expanding cerebral syndrome.

Authors:
Martin R Turner

Clin Med (Lond) 2016 Dec;16(Suppl 6):s60-s65

Medical Research Council senior clinical fellow, Nuffield Department of Clinical Neurosciences, University of Oxford, UK

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http://dx.doi.org/10.7861/clinmedicine.16-6-s60DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329564PMC
December 2016

Eye-tracking in amyotrophic lateral sclerosis: A longitudinal study of saccadic and cognitive tasks.

Amyotroph Lateral Scler Frontotemporal Degener 2015 27;17(1-2):101-11. Epub 2015 Aug 27.

a Nuffield Department of Clinical Neurosciences , University of Oxford , Oxford , UK.

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http://www.tandfonline.com/doi/full/10.3109/21678421.2015.10
Publisher Site
http://dx.doi.org/10.3109/21678421.2015.1054292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127416PMC
October 2016

Selective vulnerability in neurodegeneration: insights from clinical variants of Alzheimer's disease.

J Neurol Neurosurg Psychiatry 2016 09 8;87(9):1000-4. Epub 2016 Jan 8.

Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK Clinical Neurochemistry Laboratory, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1136/jnnp-2015-311321DOI Listing
September 2016

NEK1 variants confer susceptibility to amyotrophic lateral sclerosis.

Nat Genet 2016 09 25;48(9):1037-42. Epub 2016 Jul 25.

Department of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560030PMC
September 2016

Regionality of disease progression predicts prognosis in amyotrophic lateral sclerosis.

Amyotroph Lateral Scler Frontotemporal Degener 2015 17;16(7-8):442-7. Epub 2015 Jun 17.

a Department of Basic and Clinical Neuroscience , Institute of Psychiatry, Psychology & Neuroscience, King's College London , UK.

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August 2016

The longitudinal cerebrospinal fluid metabolomic profile of amyotrophic lateral sclerosis.

Amyotroph Lateral Scler Frontotemporal Degener 2015 29;16(7-8):456-63. Epub 2015 Jun 29.

a Nuffield Department of Clinical Neuroscience , University of Oxford , Oxford , UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720042PMC
August 2016

Mind the gap: the mismatch between clinical and imaging metrics in ALS.

Amyotroph Lateral Scler Frontotemporal Degener 2015 24;16(7-8):524-9. Epub 2015 Sep 24.

e Department of Neurology , University of Miami Miller School of Medicine , Miami, Florida , USA.

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August 2016

Romberg's test no longer stands up.

Authors:
Martin R Turner

Pract Neurol 2016 Aug 7;16(4):316. Epub 2016 Mar 7.

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http://dx.doi.org/10.1136/practneurol-2016-001365DOI Listing
August 2016

Preface to 'Neuromythology'.

Authors:
Martin R Turner

Pract Neurol 2016 Aug 7;16(4):315. Epub 2016 Mar 7.

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http://dx.doi.org/10.1136/practneurol-2016-001407DOI Listing
August 2016

Assessment of the upper motor neuron in amyotrophic lateral sclerosis.

Clin Neurophysiol 2016 07 5;127(7):2643-60. Epub 2016 May 5.

Brain and Mind Centre, University of Sydney, NSW, Australia.

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http://dx.doi.org/10.1016/j.clinph.2016.04.025DOI Listing
July 2016

Nutritional pathway for people with motor neurone disease.

Br J Community Nurs 2016 Jul;21(7):360-3

Consultant Neurologist, Oxford University Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford.

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http://dx.doi.org/10.12968/bjcn.2016.21.7.360DOI Listing
July 2016

Increased functional connectivity common to symptomatic amyotrophic lateral sclerosis and those at genetic risk.

J Neurol Neurosurg Psychiatry 2016 06 5;87(6):580-8. Epub 2016 Jan 5.

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK FMRIB Centre, John Radcliffe Hospital, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/jnnp-2015-311945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893149PMC
June 2016

Extracellular vesicles in neurodegenerative disease - pathogenesis to biomarkers.

Nat Rev Neurol 2016 06 13;12(6):346-57. Epub 2016 May 13.

Nuffield Department of Clinical Neurosciences, University of Oxford, Level 6, West Wing, John Radcliffe Hospital, Oxford OX3 9DU, UK.

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http://dx.doi.org/10.1038/nrneurol.2016.68DOI Listing
June 2016

A wider pathological network underlying breathlessness and respiratory failure in amyotrophic lateral sclerosis.

Eur Respir J 2016 06;47(6):1632-4

Nuffield Dept of Clinical Neurosciences, University of Oxford, John Radcliffe Hospital, Oxford, UK.

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http://erj.ersjournals.com/lookup/doi/10.1183/13993003.00321
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June 2016

Cerebrovascular injury as a risk factor for amyotrophic lateral sclerosis.

J Neurol Neurosurg Psychiatry 2016 Mar 10;87(3):244-6. Epub 2015 Aug 10.

Nuffield Department of Population Health, Oxford University, Oxford, UK.

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http://dx.doi.org/10.1136/jnnp-2015-311157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789816PMC
March 2016

Are neurofilaments heading for the ALS clinic?

J Neurol Neurosurg Psychiatry 2016 Jan 5;87(1):3-4. Epub 2015 Oct 5.

Nuffield Department of Clinical Neurosciences, Oxford University, Oxford, UK.

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http://jnnp.bmj.com/lookup/doi/10.1136/jnnp-2015-311934
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January 2016

Lou Gehrig and the ALS split hand.

Neurology 2015 Dec;85(22):1995

From the Sydney Medical School and Brain & Mind Centre (M.C.K.), University of Sydney, Australia; and Oxford University Nuffield Department of Clinical Neurosciences (M.R.T.), John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1212/WNL.0000000000002172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664121PMC
December 2015

Seasonal variation in Guillain-Barré syndrome: a systematic review, meta-analysis and Oxfordshire cohort study.

J Neurol Neurosurg Psychiatry 2015 Nov 24;86(11):1196-201. Epub 2014 Dec 24.

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

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http://jnnp.bmj.com/lookup/doi/10.1136/jnnp-2014-309056
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November 2015

Progress towards a neuroimaging biomarker for amyotrophic lateral sclerosis.

Lancet Neurol 2015 Aug;14(8):786-788

Nuffield Department of Clinical Neurosciences, Oxford University, Oxford, UK.

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http://dx.doi.org/10.1016/S1474-4422(15)00134-9DOI Listing
August 2015

Does dysfunction of the mirror neuron system contribute to symptoms in amyotrophic lateral sclerosis?

Clin Neurophysiol 2015 Jul 16;126(7):1288-94. Epub 2015 Feb 16.

Oxford University Nuffield Department of Clinical Neurosciences, Oxford, United Kingdom.

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http://dx.doi.org/10.1016/j.clinph.2015.02.003DOI Listing
July 2015

What does imaging reveal about the pathology of amyotrophic lateral sclerosis?

Curr Neurol Neurosci Rep 2015 Jul;15(7):45

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK,

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http://dx.doi.org/10.1007/s11910-015-0569-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443002PMC
July 2015

CSF neurofilament light chain reflects corticospinal tract degeneration in ALS.

Ann Clin Transl Neurol 2015 Jul 25;2(7):748-55. Epub 2015 May 25.

Nuffield Department of Clinical Neurosciences, University of Oxford Oxford, United Kingdom.

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http://dx.doi.org/10.1002/acn3.212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531057PMC
July 2015

The expanding syndrome of amyotrophic lateral sclerosis: a clinical and molecular odyssey.

J Neurol Neurosurg Psychiatry 2015 Jun 2;86(6):667-73. Epub 2015 Feb 2.

Queen Mary University of London, London, UK University of Lisbon, Lisbon, Portugal.

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http://dx.doi.org/10.1136/jnnp-2014-308946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4453495PMC
June 2015

Neurofilament light chain: A prognostic biomarker in amyotrophic lateral sclerosis.

Neurology 2015 Jun 1;84(22):2247-57. Epub 2015 May 1.

From the Centre for Neuroscience & Trauma (C.-H.L., G.G., J.K., A.M.), Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London; Sobell Department of Motor Neuroscience and Movement Disorders (C.-H.L., L.G.), Departments of Neuroinflammation (A.P.), Neurodegenerative Disease (P.F.), Molecular Neuroscience (K.S.), and Clinical Neuroscience (R.O.), and MRC Centre for Neuromuscular Diseases (R.O., L.G.), UCL Institute of Neurology, London; MRC Integrative Epidemiology Unit (C.M.-W.), University of Bristol; Nuffield Department of Clinical Neurosciences (E.G., K.T., M.R.T.), University of Oxford; Department of Medical Statistics (N.P.), London School of Hygiene and Tropical Medicine, London, UK; UmanDiagnostics (N.N.), Umeå, Sweden; Medicine Clinical Trial Unit (M.F.), Musgrove Park Hospital, Taunton, UK; National Hospital for Neurology and Neurosurgery (R.O., R.H., A.M.), London, UK; Neurology (J.K.), University Hospital Basel, Switzerland; North-East London and Essex MND Care and Research Centre (A.M.), London; and Basildon and Thurrock University Hospitals NHS Foundation Trust (A.M.), Basildon, UK.

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http://dx.doi.org/10.1212/WNL.0000000000001642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456658PMC
June 2015

The standard of care in amyotrophic lateral sclerosis: a centralised multidisciplinary clinic encounter sets a new benchmark for a uniquely challenging neurodegenerative disorder.

J Neurol Neurosurg Psychiatry 2015 May 30;86(5):481-2. Epub 2014 Dec 30.

Brain and Mind Research Institute, University of Sydney, Sydney, New South Wales, Australia.

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May 2015

Identification of distinct circulating exosomes in Parkinson's disease.

Ann Clin Transl Neurol 2015 Apr 6;2(4):353-61. Epub 2015 Feb 6.

Nuffield Department of Clinical Neurosciences, University of Oxford Oxford, United Kingdom ; Oxford Parkinson's Disease Centre, University of Oxford Oxford, United Kingdom.

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http://dx.doi.org/10.1002/acn3.175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4402081PMC
April 2015

Progressive hemiparesis in a 75-year-old man.

Pract Neurol 2015 Feb 24;15(1):63-71. Epub 2014 Sep 24.

Department of Clinical Neurosciences, Western General Hospital, Edinburgh, UK.

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http://dx.doi.org/10.1136/practneurol-2014-000950DOI Listing
February 2015

Use of clinical staging in amyotrophic lateral sclerosis for phase 3 clinical trials.

J Neurol Neurosurg Psychiatry 2015 Jan 24;86(1):45-9. Epub 2014 Jan 24.

King's College London, Institute of Psychiatry, Department of Clinical Neuroscience, London, UK.

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http://jnnp.bmj.com/content/early/2014/11/28/jnnp-2013-30686
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January 2015

Ensuring continued progress in biomarkers for amyotrophic lateral sclerosis.

Muscle Nerve 2015 01 24;51(1):14-8. Epub 2014 Nov 24.

Oxford University, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, West Wing Level 3, Oxford, OX3 9DU, UK.

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http://dx.doi.org/10.1002/mus.24470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270289PMC
January 2015

Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) in the older adult.

Pract Neurol 2014 Dec 14;14(6):432-6. Epub 2014 May 14.

Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

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http://pn.bmj.com/lookup/doi/10.1136/practneurol-2014-000853
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December 2014

Imaging as a biomarker in drug discovery for Alzheimer's disease: is MRI a suitable technology?

Alzheimers Res Ther 2014 30;6(4):51. Epub 2014 Jul 30.

National Institute of Mental Health, 6001 Executive Boulevard, BG NSC RM 7209, Rockville, MD 20892, USA.

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http://dx.doi.org/10.1186/alzrt276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4255417PMC
December 2014

Quantifying disease progression in amyotrophic lateral sclerosis.

Ann Neurol 2014 Nov 30;76(5):643-57. Epub 2014 Sep 30.

Department of Neurology, University of California, San Francisco, San Francisco, CA; Prince of Wales Clinical School, University of New South Wales, Randwick, Australia; Neuroscience Research Australia, Barker St, Randwick, Australia.

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http://dx.doi.org/10.1002/ana.24273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4305209PMC
November 2014

Magnetoencephalography.

Pract Neurol 2014 Oct 19;14(5):336-43. Epub 2014 Mar 19.

Nuffield Department of Clinical Neurosciences, University of Oxford, UK.

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http://pn.bmj.com/lookup/doi/10.1136/practneurol-2013-000768
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http://dx.doi.org/10.1136/practneurol-2013-000768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174130PMC
October 2014

A type 2 biomarker separates relapsing-remitting from secondary progressive multiple sclerosis.

Neurology 2014 Oct 24;83(17):1492-9. Epub 2014 Sep 24.

From the CR-UK/MRC Gray Institute for Radiation Oncology and Biology (A.M.D., J.R.L., N.R.S.), Department of Pharmacology (A.M.D., D.C.A.), Department of Chemistry (A.M.D., B.G.D., T.D.W.C.), Nuffield Department of Clinical Neurosciences (A.C., L.M., M.R.T.), and Nuffield Department of Medicine (G.K.W.), University of Oxford; and the Department of Biochemistry (J.L.G., J.P.), University of Cambridge, UK.

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http://dx.doi.org/10.1212/WNL.0000000000000905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222850PMC
October 2014

Widespread grey matter pathology dominates the longitudinal cerebral MRI and clinical landscape of amyotrophic lateral sclerosis.

Brain 2014 Sep 20;137(Pt 9):2546-55. Epub 2014 Jun 20.

1 Oxford Centre for Functional Magnetic Resonance of the Brain, University of Oxford, UK2 Nuffield Department of Clinical Neurosciences, University of Oxford, UK5 Oxford Centre for Magnetic Resonance Imaging Research, University of Oxford, UK

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http://brain.oxfordjournals.org/content/brain/137/9/2546.ful
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http://dx.doi.org/10.1093/brain/awu162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132644PMC
September 2014

Swallowing and oropharyngeal dysphagia.

Clin Med (Lond) 2014 Aug;14(4):456

Oxford University Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.7861/clinmedicine.14-4-456aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4952855PMC
August 2014

Health utility decreases with increasing clinical stage in amyotrophic lateral sclerosis.

Amyotroph Lateral Scler Frontotemporal Degener 2014 Jun 7;15(3-4):285-91. Epub 2014 Feb 7.

Department of Clinical Neuroscience, Institute of Psychiatry , King's College London, London.

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http://dx.doi.org/10.3109/21678421.2013.872149DOI Listing
June 2014

Estimating clinical stage of amyotrophic lateral sclerosis from the ALS Functional Rating Scale.

Amyotroph Lateral Scler Frontotemporal Degener 2014 Jun 10;15(3-4):279-84. Epub 2014 Apr 10.

King's College London, Institute of Psychiatry, Department of Clinical Neuroscience.

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http://dx.doi.org/10.3109/21678421.2014.897357DOI Listing
June 2014

T₂-weighted MRI detects presymptomatic pathology in the SOD1 mouse model of ALS.

J Cereb Blood Flow Metab 2014 May 5;34(5):785-93. Epub 2014 Feb 5.

CR-UK/MRC Gray Institute for Radiation Oncology and Biology, Department of Oncology, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/jcbfm.2014.19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013759PMC
May 2014