Martin Puskarjov

Martin Puskarjov

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Martin Puskarjov

Martin Puskarjov

Publications by authors named "Martin Puskarjov"

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19Publications

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Loss of non-canonical KCC2 functions promotes developmental apoptosis of cortical projection neurons.

EMBO Rep 2020 Feb 17:e48880. Epub 2020 Feb 17.

Molecular and Integrative Biosciences, Faculty of Biological and Environmental Sciences, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.15252/embr.201948880DOI Listing
February 2020

KCC2-Mediated Cl Extrusion Modulates Spontaneous Hippocampal Network Events in Perinatal Rats and Mice.

Cell Rep 2019 01;26(5):1073-1081.e3

Faculty of Biological and Environmental Sciences, Molecular and Integrative Biosciences and Neuroscience Center (HiLIFE), University of Helsinki, 00014 Helsinki, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352714PMC
January 2019

Bumepamine, a brain-permeant benzylamine derivative of bumetanide, does not inhibit NKCC1 but is more potent to enhance phenobarbital's anti-seizure efficacy.

Neuropharmacology 2018 12 21;143:186-204. Epub 2018 Sep 21.

Department of Pharmacology, Toxicology, and Pharmacy, University of Veterinary Medicine Hannover, Germany; Center for Systems Neuroscience, Hannover, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2018.09.025DOI Listing
December 2018

K-Cl Cotransporter 2-mediated Cl- Extrusion Determines Developmental Stage-dependent Impact of Propofol Anesthesia on Dendritic Spines.

Anesthesiology 2017 05;126(5):855-867

From the Department of Biosciences and Neuroscience Center (HiLIFE), University of Helsinki, Helsinki, Finland (M.P., M.M., P.B., K.K.); Division of Biological and Environmental Sciences and Technology, King Abdullah University of Science and Technology, Thuwal, Kingdom of Saudi Arabia (H.F.); Department of Anesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva, Geneva, Switzerland (A.B., T.B., C.-M.L., L.V.); Department of Fundamental Neurosciences, University of Geneva Medical School, Geneva, Switzerland (A.B., T.B., K.D., L.V.); and Institute of Experimental Medicine of the Hungarian Academy of Sciences, Budapest, Hungary (K.D.). Current position: Institute of Physiology I, Westfälische Wilhelms-University Münster, Münster, Germany (P.B.).

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http://dx.doi.org/10.1097/ALN.0000000000001587DOI Listing
May 2017

Forebrain-independent generation of hyperthermic convulsions in infant rats.

Epilepsia 2016 Jan 7;57(1):e1-6. Epub 2015 Nov 7.

Department of Biosciences and Neuroscience Center, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1111/epi.13230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4738399PMC
January 2016

BDNF is required for seizure-induced but not developmental up-regulation of KCC2 in the neonatal hippocampus.

Neuropharmacology 2015 Jan 16;88:103-9. Epub 2014 Sep 16.

Department of Biosciences and Neuroscience Center, University of Helsinki, FI-00014 Helsinki, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2014.09.005DOI Listing
January 2015

Cation-chloride cotransporters in neuronal development, plasticity and disease.

Nat Rev Neurosci 2014 Oct;15(10):637-54

Department of Biosciences, University of Helsinki, 00014 Helsinki, Finland.

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http://dx.doi.org/10.1038/nrn3819DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294553PMC
October 2014

GABA actions and ionic plasticity in epilepsy.

Curr Opin Neurobiol 2014 Jun 30;26:34-41. Epub 2013 Nov 30.

Department of Biosciences, University of Helsinki, FI-00014 Helsinki, Finland; Neuroscience Center, University of Helsinki, FI-00014 Helsinki, Finland.

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http://dx.doi.org/10.1016/j.conb.2013.11.004DOI Listing
June 2014

Pharmacotherapeutic targeting of cation-chloride cotransporters in neonatal seizures.

Epilepsia 2014 Jun 6;55(6):806-18. Epub 2014 May 6.

Department of Biosciences and Neuroscience Center, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1111/epi.12620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284054PMC
June 2014

Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2.

Trends Neurosci 2013 Dec 15;36(12):726-737. Epub 2013 Oct 15.

Department of Neuroscience, Tufts University School of Medicine, Boston, MA 02111, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S01662236130015
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http://dx.doi.org/10.1016/j.tins.2013.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381966PMC
December 2013

Cation-chloride cotransporters NKCC1 and KCC2 as potential targets for novel antiepileptic and antiepileptogenic treatments.

Neuropharmacology 2013 Jun 15;69:62-74. Epub 2012 Jun 15.

Department of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine Hannover, Hannover, Germany.

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http://dx.doi.org/10.1016/j.neuropharm.2012.05.045DOI Listing
June 2013

An ion transport-independent role for the cation-chloride cotransporter KCC2 in dendritic spinogenesis in vivo.

Cereb Cortex 2013 Feb 17;23(2):378-88. Epub 2012 Feb 17.

Center for Psychiatric Neurosciences, Department of Psychiatry, Lausanne University Hospital, 1008 Prilly-Lausanne, Switzerland.

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http://dx.doi.org/10.1093/cercor/bhs027DOI Listing
February 2013

Activity-dependent cleavage of the K-Cl cotransporter KCC2 mediated by calcium-activated protease calpain.

J Neurosci 2012 Aug;32(33):11356-64

Department of Biosciences and Neuroscience Center, University of Helsinki, FI-00014 Helsinki, Finland.

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http://dx.doi.org/10.1523/JNEUROSCI.6265-11.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6621186PMC
August 2012

A single seizure episode leads to rapid functional activation of KCC2 in the neonatal rat hippocampus.

J Neurosci 2010 Sep;30(36):12028-35

Department of Biosciences and Neuroscience Center, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1523/JNEUROSCI.3154-10.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633538PMC
September 2010