Martin Pollak

Martin Pollak

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APOL1 gene variants and kidney disease in whites: the cardiovascular health study.

Nephrol Dial Transplant 2019 Oct 3. Epub 2019 Oct 3.

Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.

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http://dx.doi.org/10.1093/ndt/gfz186DOI Listing
October 2019

Contributions of Rare Gene Variants to Familial and Sporadic FSGS.

J Am Soc Nephrol 2019 Sep 15;30(9):1625-1640. Epub 2019 Jul 15.

Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts;

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http://www.jasn.org/lookup/doi/10.1681/ASN.2019020152
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http://dx.doi.org/10.1681/ASN.2019020152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727251PMC
September 2019

APOL1 Kidney Risk Variants Induce Cell Death Mitochondrial Translocation and Opening of the Mitochondrial Permeability Transition Pore.

J Am Soc Nephrol 2019 Sep 26. Epub 2019 Sep 26.

Renal Division, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts

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http://dx.doi.org/10.1681/ASN.2019020114DOI Listing
September 2019

Autosomal Recessive Alport Syndrome Unveiled by Pregnancy.

Nephron 2019 Aug 13:1-5. Epub 2019 Aug 13.

Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA,

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http://dx.doi.org/10.1159/000502147DOI Listing
August 2019

Apolipoprotein L1 (APOL1) risk variant toxicity depends on the haplotype background.

Kidney Int 2019 Aug 1. Epub 2019 Aug 1.

Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2019.07.010DOI Listing
August 2019

APOL1-Associated Kidney Disease in Brazil.

Kidney Int Rep 2019 Jul 20;4(7):923-929. Epub 2019 Mar 20.

Division of Nephrology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1016/j.ekir.2019.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611925PMC
July 2019

Recruitment of APOL1 kidney disease risk variants to lipid droplets attenuates cell toxicity.

Proc Natl Acad Sci U S A 2019 02 7;116(9):3712-3721. Epub 2019 Feb 7.

Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215;

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http://dx.doi.org/10.1073/pnas.1820414116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397558PMC
February 2019

Guided tissue organization and disease modeling in a kidney tubule array.

Biomaterials 2018 11 10;183:295-305. Epub 2018 Aug 10.

Harvard Center for Polycystic Kidney Disease Research and Renal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Harvard Stem Cell Institute, Cambridge, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2018.07.059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6671629PMC
November 2018

Association of APOL1 With Heart Failure With Preserved Ejection Fraction in Postmenopausal African American Women.

JAMA Cardiol 2018 08;3(8):712-720

Molecular Genetic Epidemiology Section, Basic Research Laboratory, Basic Science Program, National Cancer Institute Leidos Biomedical Research, Frederick National Laboratory, Frederick, Maryland.

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http://cardiology.jamanetwork.com/article.aspx?doi=10.1001/j
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http://dx.doi.org/10.1001/jamacardio.2018.1827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143074PMC
August 2018

Mechanical challenges and cytoskeletal impairments in focal segmental glomerulosclerosis.

Am J Physiol Renal Physiol 2018 05 24;314(5):F921-F925. Epub 2018 Jan 24.

Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center , Boston, Massachusetts.

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http://dx.doi.org/10.1152/ajprenal.00641.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6031906PMC
May 2018

modifies -induced kidney disease risk.

Proc Natl Acad Sci U S A 2018 03 12;115(13):3446-3451. Epub 2018 Mar 12.

Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215;

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http://dx.doi.org/10.1073/pnas.1716113115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879665PMC
March 2018

Disease-causing mutation in α-actinin-4 promotes podocyte detachment through maladaptation to periodic stretch.

Proc Natl Acad Sci U S A 2018 02 29;115(7):1517-1522. Epub 2018 Jan 29.

Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215;

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http://dx.doi.org/10.1073/pnas.1717870115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5816190PMC
February 2018

Introduction: APOL1-Associated Kidney Disease.

Authors:
Martin R Pollak

Semin Nephrol 2017 11;37(6):489

Division of Nephrology, Beth Israel Deaconess Medical Center, Harvard Medical School Boston, MA.

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http://dx.doi.org/10.1016/j.semnephrol.2017.07.001DOI Listing
November 2017

Functional Validation of an Alpha-Actinin-4 Mutation as a Potential Cause of an Aggressive Presentation of Adolescent Focal Segmental Glomerulosclerosis: Implications for Genetic Testing.

PLoS One 2016 15;11(12):e0167467. Epub 2016 Dec 15.

Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0167467PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5158186PMC
July 2017

Most ApoL1 Is Secreted by the Liver.

J Am Soc Nephrol 2017 Apr 8;28(4):1079-1083. Epub 2016 Dec 8.

Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1681/ASN.2016040441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373451PMC
April 2017

Parathyroid hormone controls paracellular Ca transport in the thick ascending limb by regulating the tight-junction protein Claudin14.

Proc Natl Acad Sci U S A 2017 04 3;114(16):E3344-E3353. Epub 2017 Apr 3.

Division of Bone and Mineral Research, Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, MA 02115;

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http://dx.doi.org/10.1073/pnas.1616733114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402431PMC
April 2017

Personalized Comments on Challenges and Opportunities in Kidney Disease Therapeutics: The Glom-NExT Symposium.

Semin Nephrol 2016 11;36(6):448

Broad Institute of Massachusetts Institute of Technology, and Harvard, Cambridge, MA; Center for Human Genetic Research and Diabetes Research Center, Diabetes Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1016/j.semnephrol.2016.09.005DOI Listing
November 2016

Genetics of Familial FSGS.

Authors:
Martin Pollak

Semin Nephrol 2016 11;36(6):467-472

Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.semnephrol.2016.09.010DOI Listing
November 2016

Non-muscle myosin-IIA is critical for podocyte f-actin organization, contractility, and attenuation of cell motility.

Cytoskeleton (Hoboken) 2016 Aug 21;73(8):377-95. Epub 2016 Jul 21.

Department of Pathology and Laboratory Medicine, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts.

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http://dx.doi.org/10.1002/cm.21313DOI Listing
August 2016

Mice with mutant Inf2 show impaired podocyte and slit diaphragm integrity in response to protamine-induced kidney injury.

Kidney Int 2016 08 24;90(2):363-372. Epub 2016 Jun 24.

Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA; Harvard Medical School, Boston, Massachusetts, USA; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, USA. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2016.04.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363079PMC
August 2016

Apolipoprotein L1 and Kidney Disease in African Americans.

Trends Endocrinol Metab 2016 Apr 3;27(4):204-215. Epub 2016 Mar 3.

Beth Israel Deaconess Medical Center, Harvard Medical School, 99 Brookline Avenue, RN301, Boston, MA 02215, USA.

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http://dx.doi.org/10.1016/j.tem.2016.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811340PMC
April 2016

Copy Number Variation at the APOL1 Locus.

PLoS One 2015 1;10(5):e0125410. Epub 2015 May 1.

Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America; Harvard Medical School, Boston, Massachusetts, United States of America; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0125410PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416782PMC
February 2016

APOL1 Genotype, Kidney and Cardiovascular Disease, and Death in Older Adults.

Arterioscler Thromb Vasc Biol 2016 Feb 3;36(2):398-403. Epub 2015 Dec 3.

From the Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA (K.J.M., J.T., D.J.F., M.R.P.); Veterans Affairs San Diego Healthcare System and Division of Nephrology-Hypertension, University of California San Diego School of Medicine (J.H.I.); Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA (L.H.K.); and Department of Pathology and Laboratory Medicine, University of Vermont, Burlington (R.P.T.).

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http://dx.doi.org/10.1161/ATVBAHA.115.305970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732891PMC
February 2016

APOL1 kidney disease risk variants cause cytotoxicity by depleting cellular potassium and inducing stress-activated protein kinases.

Proc Natl Acad Sci U S A 2016 Jan 23;113(4):830-7. Epub 2015 Dec 23.

Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215; Harvard Medical School, Boston, MA 02215;

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http://dx.doi.org/10.1073/pnas.1522913113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743809PMC
January 2016

Effect Size Does Matter: The Long Road to Mechanistic Insight From Genome-Wide Association.

Circulation 2015 Nov 20;132(21):1943-5. Epub 2015 Oct 20.

From the Cardiovascular Division, Brigham and Women's Hospital, Boston, MA (C.A.M.); Department of Medicine, Harvard Medical School, Boston, MA (C.A.M., M.R.P.); and Renal Division, Beth Israel Deaconess Medical Center, Boston, MA (M.R.P.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.019306DOI Listing
November 2015

The role of alpha-actinin-4 in human kidney disease.

Cell Biosci 2015 18;5:44. Epub 2015 Aug 18.

Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215 USA.

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http://dx.doi.org/10.1186/s13578-015-0036-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545552PMC
August 2015

Calcium Sensing in the Renal Tubule.

Physiology (Bethesda) 2015 Jul;30(4):317-26

Université Paris-Descartes, Sorbonne Paris-Cité, Centre de Recherche des Cordeliers, INSERM UMRS 1138, Service de Physiologie, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France

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http://dx.doi.org/10.1152/physiol.00042.2014DOI Listing
July 2015

Modifiers of Cardiac Phenotypes.

Authors:
Martin R Pollak

Circ Cardiovasc Genet 2015 Jun;8(3):425-6

Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1161/CIRCGENETICS.115.001122DOI Listing
June 2015

Opportunities and Challenges of Genotyping Patients With Nephrotic Syndrome in the Genomic Era.

Semin Nephrol 2015 May;35(3):212-21

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1016/j.semnephrol.2015.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745990PMC
May 2015

Innate immunity pathways regulate the nephropathy gene Apolipoprotein L1.

Kidney Int 2015 Feb 6;87(2):332-42. Epub 2014 Aug 6.

1] Renal Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA [2] Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ki.2014.270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4312530PMC
February 2015

Discovery of new glomerular disease-relevant genes by translational profiling of podocytes in vivo.

Kidney Int 2014 Dec 18;86(6):1116-29. Epub 2014 Jun 18.

1] Renal Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA [2] Kidney Group, Harvard Stem Cell Institute, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/ki.2014.204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4245460PMC
December 2014

Human Kidney Disease-causing INF2 Mutations Perturb Rho/Dia Signaling in the Glomerulus.

EBioMedicine 2014 Dec 13;1(2-3):107-15. Epub 2014 Nov 13.

Nephrology Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, United States ; Harvard Medical School, Boston, MA 02215, United States ; Broad Institute of Harvard and MIT, Cambridge, MA, United States.

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http://dx.doi.org/10.1016/j.ebiom.2014.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457406PMC
December 2014

Mutations in PAX2 associate with adult-onset FSGS.

J Am Soc Nephrol 2014 Sep 27;25(9):1942-53. Epub 2014 Mar 27.

Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts;

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http://dx.doi.org/10.1681/ASN.2013070686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147972PMC
September 2014

The role of the calcium-sensing receptor in disorders of abnormal calcium handling and cardiovascular disease.

Curr Opin Nephrol Hypertens 2014 Sep;23(5):494-501

aDivision of Nephrology, Beth Israel Deaconess Medical Center bDivision of Nephrology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/MNH.0000000000000042DOI Listing
September 2014

Familial FSGS.

Authors:
Martin R Pollak

Adv Chronic Kidney Dis 2014 Sep;21(5):422-5

Beth Israel Deaconess Medical Center, Boston, MA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15485595140009
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http://dx.doi.org/10.1053/j.ackd.2014.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197186PMC
September 2014

The glomerulus: the sphere of influence.

Clin J Am Soc Nephrol 2014 Aug 29;9(8):1461-9. Epub 2014 May 29.

Brown Medical School, Brown University, Providence, Rhode Island.

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http://dx.doi.org/10.2215/CJN.09400913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123398PMC
August 2014

Research capacity. Enabling the genomic revolution in Africa.

Authors:
Charles Rotimi Akin Abayomi Alash'le Abimiku Victoria May Adabayeri Clement Adebamowo Ezekiel Adebiyi Adebowale D Ademola Adebowale Adeyemo Dwomoa Adu Dissou Affolabi Godfred Agongo Samuel Ajayi Sally Akarolo-Anthony Rufus Akinyemi Albert Akpalu Marianne Alberts Orlando Alonso Betancourt Ahmed Mansour Alzohairy Gobena Ameni Olukemi Amodu Gabriel Anabwani Kristian Andersen Fatiu Arogundade Oyedunni Arulogun Danny Asogun Rasheed Bakare Naby Balde Mary Lynn Baniecki Christine Beiswanger Alia Benkahla Lara Bethke Micheal Boehnke Vincent Boima James Brandful Andrew I Brooks Frank C Brosius Chester Brown Bruno Bucheton David T Burke Barrington G Burnett Stacy Carrington-Lawrence Nadia Carstens John Chisi Alan Christoffels Richard Cooper Heather Cordell Nigel Crowther Talishiea Croxton Jantina de Vries Leslie Derr Peter Donkor Seydou Doumbia Audrey Duncanson Ivy Ekem Ahmed El Sayed Mark E Engel John C K Enyaru Dean Everett Faisal M Fadlelmola Eyitayo Fakunle Kenneth H Fischbeck Anne Fischer Onikepe Folarin Junaid Gamieldien Robert F Garry Simani Gaseitsiwe Rasheed Gbadegesin Anita Ghansah Maria Giovanni Parham Goesbeck F Xavier Gomez-Olive Donald S Grant Ravnit Grewal Mark Guyer Neil A Hanchard Christian T Happi Scott Hazelhurst Branwen J Hennig Christiane Hertz- Fowler Winston Hide Friedhelm Hilderbrandt Christopher Hugo-Hamman Muntaser E Ibrahim Regina James Yasmina Jaufeerally-Fakim Carolyn Jenkins Ute Jentsch Pan-Pan Jiang Moses Joloba Victor Jongeneel Fourie Joubert Mukthar Kader Kathleen Kahn Pontiano Kaleebu Saidi H Kapiga Samar Kamal Kassim Ishmael Kasvosve Jonathan Kayondo Bernard Keavney Adeodata Kekitiinwa Sheik Humarr Khan Paul Kimmel Mary-Claire King Robert Kleta Mathurin Koffi Jeffrey Kopp Matthias Kretzler Judit Kumuthini Samuel Kyobe Catherine Kyobutungi Daniel T Lackland Karen A Lacourciere Guida Landouré Rita Lawlor Thomas Lehner Maia Lesosky Naomi Levitt Katherine Littler Zane Lombard Jeanne F Loring Sylvester Lyantagaye Annette Macleod Ebony B Madden Chengetai R Mahomva Julie Makani Manmak Mamven Marape Marape Graeme Mardon Patricia Marshall Darren P Martin Daniel Masiga Robin Mason Michael Mate-Kole Enock Matovu Mary Mayige Bongani M Mayosi Jean Claude Mbanya Sheryl A McCurdy Mark I McCarthy Helen McIlleron S O Mc'Ligeyo Corrine Merle Ana Olga Mocumbi Charles Mondo John V Moran Ayesha Motala Marva Moxey-Mims Wata Sununguko Mpoloka Chisomo L Msefula Thuli Mthiyane Nicola Mulder Gebregziab her Mulugeta Dieuodonne Mumba John Musuku Mo Nagdee Oyekanmi Nash Daouda Ndiaye Anh Quynh Nguyen Mark Nicol Oathokwa Nkomazana Shane Norris Betty Nsangi Alexander Nyarko Moffat Nyirenda Eileen Obe Reginald Obiakor Abraham Oduro Solomon F Ofori-Acquah Okechukwu Ogah Stephen Ogendo Kwaku Ohene-Frempong Akinlolu Ojo Timothy Olanrewaju John Oli Charlotte Osafo Odile Ouwe Missi Oukem-Boyer Bruce Ovbiagele Andrew Owen Mayowa Ojo Owolabi Lukman Owolabi Ellis Owusu-Dabo Guillaume Pare Rulan Parekh Hugh G Patterton Margaret B Penno Jane Peterson Rembert Pieper Jacob Plange-Rhule Martin Pollak Julia Puzak Rajkumar S Ramesar Michele Ramsay Rebekah Rasooly Shiksha Reddy Pardis C Sabeti Kwamena Sagoe Tunde Salako Oumar Samassékou Manjinder S Sandhu Osman Sankoh Fred Stephen Sarfo Marie Sarr Gasnat Shaboodien Issa Sidibe Gustave Simo Martin Simuunza Liam Smeeth Eugene Sobngwi Himla Soodyall Hermann Sorgho Oumou Sow Bah Sudha Srinivasan Dan J Stein Ezra S Susser Carmen Swanepoel Godfred Tangwa Andrew Tareila Ozlem Tastan Bishop Bamidele Tayo Nicki Tiffin Halidou Tinto Ekaete Tobin Stephen Meir Tollman Mahamadou Traoré Marsha J Treadwell Jennifer Troyer Masego Tsimako-Johnstone Vincent Tukei Ifeoma Ulasi Nzovu Ulenga Beverley van Rooyen Ablo Prudence Wachinou Salina P Waddy Alisha Wade Misaki Wayengera James Whitworth Louise Wideroff Cheryl A Winkler Sarah Winnicki Ambroise Wonkam Mengistu Yewondwos Tadase sen Nathan Yozwiak Heather Zar

Science 2014 Jun;344(6190):1346-8

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http://dx.doi.org/10.1126/science.1251546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138491PMC
June 2014

Genetic testing for nephrotic syndrome and FSGS in the era of next-generation sequencing.

Kidney Int 2014 May 5;85(5):1030-8. Epub 2014 Mar 5.

1] Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA [2] Department of Medicine, Toronto General Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/ki.2014.48DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118212PMC
May 2014

Evolution of the primate trypanolytic factor APOL1.

Proc Natl Acad Sci U S A 2014 May 7;111(20):E2130-9. Epub 2014 May 7.

Department of Microbiology, New York University School of Medicine, New York, NY 10016;Department of Biological Sciences, Hunter College at City University of New York, New York, NY 10065;

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http://dx.doi.org/10.1073/pnas.1400699111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034216PMC
May 2014

Frequency of rare allelic variation in candidate genes among individuals with low and high urinary calcium excretion.

PLoS One 2013 26;8(8):e71885. Epub 2013 Aug 26.

Division of Nephrology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America ; Division of Nephrology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0071885PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753300PMC
April 2014

Increased burden of cardiovascular disease in carriers of APOL1 genetic variants.

Circ Res 2014 Feb 30;114(5):845-50. Epub 2013 Dec 30.

From the Department of Genetics, Harvard Medical School, Boston, MA (K.I., A.G.B., M.G.P., S.R.D., J.N.H., J.G.S., C.S.); Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge (K.I., A.G.B., J.F., G.G., N.G., S.B.G., C.N.-C., S.K., J.N.H., D.M.A., M.R.P., J.G.S., C.S.); Center for Human Genetic Research, Massachusetts General Hospital, Boston (J.F., C.N.-C., S.K., D.M.A.); Division of Nephrology, Department of Medicine (D.J.F., G.G., M.R.P.) and Center for Vascular Biology Research, Department of Medicine (D.J.F.), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA; Departments of Medicine (H.A.T., E.R.F.) and Physiology and Biophysics (J.G.W.), University of Mississippi Medical Center, Jackson; Jackson State University, MS (H.A.T.); Tougaloo College, MS (H.A.T.); Cardiology Division, Massachusetts General Hospital, Boston (C.N.-C., S.K.); Divisions of Genetics and Endocrinology and Program in Genomics, Children's Hospital, Boston, MA (J.N.H.); and Howard Hughes Medical Institute and Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (C.S.).

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http://dx.doi.org/10.1161/CIRCRESAHA.114.302347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982584PMC
February 2014

Exome sequencing and in vitro studies identified podocalyxin as a candidate gene for focal and segmental glomerulosclerosis.

Kidney Int 2014 Jan 18;85(1):124-33. Epub 2013 Sep 18.

1] Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA [2] Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ki.2013.354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4068013PMC
January 2014

Pregnancy-associated polyuria in familial renal glycosuria.

Am J Kidney Dis 2013 Dec 18;62(6):1160-4. Epub 2013 Jul 18.

Division of Nephrology, Beth Israel Deaconess Medical Center, Boston, MA; Division of Nephrology, Brigham and Women's Hospital, Boston, MA.

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http://dx.doi.org/10.1053/j.ajkd.2013.05.018DOI Listing
December 2013

Health disparities in kidney disease--emerging data from the human genome.

N Engl J Med 2013 Dec 9;369(23):2260-1. Epub 2013 Nov 9.

From the Divisions of Nephrology, Massachusetts General Hospital (W.W.W.) and Beth Israel Deaconess Medical Center (M.R.P.), and Harvard Medical School (W.W.W., M.R.P.) - all in Boston; and the Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA (W.W.W., M.R.P.).

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http://dx.doi.org/10.1056/NEJMe1312797DOI Listing
December 2013

Parathyroid hormone ablation alters erythrocyte parameters that are rescued by calcium-sensing receptor gene deletion.

Eur J Haematol 2013 Jul 27;91(1):37-45. Epub 2013 Apr 27.

Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3689863PMC
July 2013

Inverted formin 2 regulates actin dynamics by antagonizing Rho/diaphanous-related formin signaling.

J Am Soc Nephrol 2013 May 25;24(6):917-29. Epub 2013 Apr 25.

Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665394PMC
May 2013

CaSR-mediated interactions between calcium and magnesium homeostasis in mice.

Am J Physiol Endocrinol Metab 2013 Apr 29;304(7):E724-33. Epub 2013 Jan 29.

Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1152/ajpendo.00557.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625753PMC
April 2013

APOL1 variants and kidney disease in people of recent African ancestry.

Nat Rev Nephrol 2013 04 26;9(4):240-4. Epub 2013 Feb 26.

Stanley Center, Broad Institute, Cambridge, MA 02142, USA.

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http://www.nature.com/articles/nrneph.2013.34
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April 2013

Mutations in the INF2 gene account for a significant proportion of familial but not sporadic focal and segmental glomerulosclerosis.

Kidney Int 2013 Feb 26;83(2):316-22. Epub 2012 Sep 26.

Division of Nephrology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1038/ki.2012.349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647680PMC
February 2013

Interactions between calcium and phosphorus in the regulation of the production of fibroblast growth factor 23 in vivo.

Am J Physiol Endocrinol Metab 2013 Feb 11;304(3):E310-20. Epub 2012 Dec 11.

Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1152/ajpendo.00460.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566433PMC
February 2013

Stress-enhanced gelation: a dynamic nonlinearity of elasticity.

Phys Rev Lett 2013 Jan 3;110(1):018103. Epub 2013 Jan 3.

Department of Physics, Harvard University, Cambridge, Massachusetts 02138, USA.

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January 2013

SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activity.

BMC Cell Biol 2012 Nov 21;13:33. Epub 2012 Nov 21.

Division of Nephrology, Beth Israel Deaconess Medical Center, Research North 304B, 99 Brookline Ave, Boston, MA 02215, USA.

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http://dx.doi.org/10.1186/1471-2121-13-33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3520717PMC
November 2012

The calcium-sensing receptor complements parathyroid hormone-induced bone turnover in discrete skeletal compartments in mice.

Am J Physiol Endocrinol Metab 2012 Apr 24;302(7):E841-51. Epub 2012 Jan 24.

Calcium Research Laboratory, McGill University Health Centre, Montreal, QC, Canada.

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http://dx.doi.org/10.1152/ajpendo.00599.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3330707PMC
April 2012

APOL1 and kidney disease.

Curr Opin Nephrol Hypertens 2012 Mar;21(2):179-82

Nephrology Division, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.

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March 2012

Population-based risk assessment of APOL1 on renal disease.

J Am Soc Nephrol 2011 Nov 13;22(11):2098-105. Epub 2011 Oct 13.

Renal Division, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA.

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November 2011

Nonlinear viscoelasticity of actin transiently cross-linked with mutant α-actinin-4.

J Mol Biol 2011 Sep 6;411(5):1062-71. Epub 2011 Jul 6.

Department of Physics, Harvard University, Cambridge, MA 02138, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5419588PMC
September 2011

Genetics of kidney failure and the evolving story of APOL1.

J Clin Invest 2011 Sep 1;121(9):3367-74. Epub 2011 Sep 1.

Nephrology Division, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163957PMC
September 2011

A suPAR circulating factor causes kidney disease.

Nat Med 2011 Aug 4;17(8):926-7. Epub 2011 Aug 4.

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August 2011

The calcium-sensing receptor mediates bone turnover induced by dietary calcium and parathyroid hormone in neonates.

J Bone Miner Res 2011 May;26(5):1057-71

Laboratory of Reproductive Medicine, Research Center for Bone and Stem Cells, Nanjing Medical University, Nanjing, Jiangsu, People's Republic of China.

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May 2011

Rho activation of mDia formins is modulated by an interaction with inverted formin 2 (INF2).

Proc Natl Acad Sci U S A 2011 Feb 28;108(7):2933-8. Epub 2011 Jan 28.

Nephrology Division, Department of Medicine, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China.

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February 2011

Cross-link-governed dynamics of biopolymer networks.

Phys Rev Lett 2010 Dec 30;105(23):238101. Epub 2010 Nov 30.

Department of Physics and Astronomy, Vrije Universiteit, Amsterdam, The Netherlands.

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December 2010

Direct dynamin-actin interactions regulate the actin cytoskeleton.

EMBO J 2010 Nov 8;29(21):3593-606. Epub 2010 Oct 8.

Nephrology Division, Department of Medicine, Harvard Medical School and Massachusetts General Hospital, Charlestown, MA 02129, USA.

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November 2010

α-actinin-4 is essential for maintaining the spreading, motility and contractility of fibroblasts.

PLoS One 2010 Nov 11;5(11):e13921. Epub 2010 Nov 11.

Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978680PMC
November 2010

A risk allele for focal segmental glomerulosclerosis in African Americans is located within a region containing APOL1 and MYH9.

Kidney Int 2010 Oct 28;78(7):698-704. Epub 2010 Jul 28.

Renal Division, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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October 2010

VEGF receptors and glomerular function.

J Am Soc Nephrol 2010 Oct 16;21(10):1599-600. Epub 2010 Sep 16.

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October 2010

Calcium-sensing receptor is a physiologic multimodal chemosensor regulating gastric G-cell growth and gastrin secretion.

Proc Natl Acad Sci U S A 2010 Oct 27;107(41):17791-6. Epub 2010 Sep 27.

Digestive Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-1804, USA.

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http://dx.doi.org/10.1073/pnas.1009078107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955134PMC
October 2010

The apolipoprotein L1 (APOL1) gene and nondiabetic nephropathy in African Americans.

J Am Soc Nephrol 2010 Sep 5;21(9):1422-6. Epub 2010 Aug 5.

Section on Nephrology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1053, USA.

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September 2010

Genetics and genetic testing in kidney disease: introduction.

Authors:
Martin R Pollak

Semin Nephrol 2010 Jul;30(4):355

Division of Nephrology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.

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July 2010

Metabolite profiling identifies markers of uremia.

J Am Soc Nephrol 2010 Jun 8;21(6):1041-1051. Epub 2010 Apr 8.

Massachusetts General Hospital, 149 13th Street, 8th Floor, Boston, MA, USA.

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http://dx.doi.org/10.1681/ASN.2009111132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900954PMC
June 2010

Improved IBD detection using incomplete haplotype information.

BMC Genet 2010 Jun 30;11:58. Epub 2010 Jun 30.

Department of Mathematics, Dartmouth College, Hanover NH 03755, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914765PMC
June 2010

Alterations in phosphorus, calcium and PTHrP contribute to defects in dental and dental alveolar bone formation in calcium-sensing receptor-deficient mice.

Development 2010 Mar 11;137(6):985-92. Epub 2010 Feb 11.

Institute of Dental Research, Stomatological College, Nanjing Medical University, Nanjing, Jiangsu 210029, P R of China.

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http://dx.doi.org/10.1242/dev.045898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834458PMC
March 2010

Expanding the spectrum of NPHS1-associated disease.

Authors:
Martin R Pollak

Kidney Int 2009 Dec;76(12):1221-3

Department of Medicine, Renal Division, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

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December 2009

Surprising results following conditional podocyte inactivation.

Authors:
Martin R Pollak

J Am Soc Nephrol 2009 Oct 17;20(10):2086-8. Epub 2009 Sep 17.

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October 2009

The calcium-sensing receptor (CaSR) defends against hypercalcemia independently of its regulation of parathyroid hormone secretion.

Am J Physiol Endocrinol Metab 2009 Oct;297(4):E915-23

Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1152/ajpendo.00315.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763782PMC
October 2009

The full-length calcium-sensing receptor dampens the calcemic response to 1alpha,25(OH)2 vitamin D3 in vivo independently of parathyroid hormone.

Am J Physiol Renal Physiol 2009 Sep 27;297(3):F720-8. Epub 2009 May 27.

Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://www.physiology.org/doi/10.1152/ajprenal.00164.2009
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739709PMC
September 2009

Patients with ACTN4 mutations demonstrate distinctive features of glomerular injury.

J Am Soc Nephrol 2009 May 8;20(5):961-8. Epub 2009 Apr 8.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657996PMC
May 2009