Martin Neuenschwander

Martin Neuenschwander

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Martin Neuenschwander

Martin Neuenschwander

Publications by authors named "Martin Neuenschwander"

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32Publications

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Drug discovery with an RBM20 dependent titin splice reporter identifies cardenolides as lead structures to improve cardiac filling.

PLoS One 2018 11;13(6):e0198492. Epub 2018 Jun 11.

Neuromuscular and Cardiovascular Cell Biology, Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198492PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995442PMC
December 2018

A Chemical Disruptor of the ClpX Chaperone Complex Attenuates the Virulence of Multidrug-Resistant Staphylococcus aureus.

Angew Chem Int Ed Engl 2017 12 12;56(49):15746-15750. Epub 2017 Oct 12.

Center for Integrated Protein Science at the Department of Chemistry, Technische Universität München, Lichtenbergstrasse 4, 85747, Garching, Germany.

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http://dx.doi.org/10.1002/anie.201708454DOI Listing
December 2017

Identification of a Novel Benzimidazole Pyrazolone Scaffold That Inhibits KDM4 Lysine Demethylases and Reduces Proliferation of Prostate Cancer Cells.

SLAS Discov 2017 08 27;22(7):801-812. Epub 2017 Mar 27.

1 Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.

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http://dx.doi.org/10.1177/2472555217699157DOI Listing
August 2017

Small Molecules Targeting Human N-Acetylmannosamine Kinase.

Chembiochem 2017 07 27;18(13):1279-1285. Epub 2017 Apr 27.

Leibniz-Institut für Molekulare Pharmakologie, Robert-Roessle-Strasse 10, 13125, Berlin, Germany.

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http://dx.doi.org/10.1002/cbic.201700066DOI Listing
July 2017

A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis.

Cancer Res 2016 Feb 8;76(4):891-901. Epub 2015 Dec 8.

Cancer Research Program, Max Delbrück Center for Molecular Medicine in the Helmholtz Society, Berlin, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-1519DOI Listing
February 2016

[Online addictive disease].

Ther Umsch 2014 Oct;71(10):599-607

Berner Gesundheit - Stiftung für Gesundheitsförderung und Suchtfragen, Bern.

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http://dx.doi.org/10.1024/0040-5930/a000559DOI Listing
October 2014

Tractable synthesis of multipurpose screening compounds with under-represented molecular features for an open access screening platform.

Mol Divers 2014 Aug 1;18(3):483-95. Epub 2014 Apr 1.

Institute of Pharmacy, Ernst -Moritz-Arndt-University, Friedrich-Ludwig-Jahn-Str. 17, 17487 , Greifswald, Germany.

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http://dx.doi.org/10.1007/s11030-014-9518-6DOI Listing
August 2014

Naturalistic study on ICD-10 personality disorders.

Int J Psychiatry Clin Pract 2006 ;10(4):252-7

Department of Psychiatry, Burghölzli Hospital, University of Zurich, Switzerland.

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http://dx.doi.org/10.1080/13651500600650067DOI Listing
June 2014

Identification of a new membrane-permeable inhibitor against inositol-1,4,5-trisphosphate-3-kinase A.

Biochem Biophys Res Commun 2013 Sep 24;439(2):228-34. Epub 2013 Aug 24.

Institut für Biochemie und Signaltransduktion, UKE Hamburg, Martinistr. 52, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2013.08.053DOI Listing
September 2013

Pharmacologic inhibition of MALT1 protease by phenothiazines as a therapeutic approach for the treatment of aggressive ABC-DLBCL.

Cancer Cell 2012 Dec;22(6):825-37

Research Unit Cellular Signal Integration, Helmholtz Zentrum München-German Research Center for Environmental Health, Institute of Molecular Toxicology and Pharmacology, Ingolstädter Landstrasse. 1, 85764 Neuherberg, Germany.

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http://dx.doi.org/10.1016/j.ccr.2012.11.002DOI Listing
December 2012

Sustainable synthesis and automated deposition: an accessible discovery screening library of fragment-like purines.

Mol Divers 2012 Aug 14;16(3):541-51. Epub 2012 Aug 14.

Institute of Pharmacy, Ernst-Moritz-Arndt-University, Friedrich-Ludwig-Jahn-Str. 17, 17487 Greifswald, Germany.

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http://link.springer.com/10.1007/s11030-012-9386-x
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http://dx.doi.org/10.1007/s11030-012-9386-xDOI Listing
August 2012

An N-terminal protein degradation tag enables robust selection of highly active enzymes.

Biochemistry 2011 Oct 14;50(40):8594-602. Epub 2011 Sep 14.

Laboratory of Organic Chemistry, ETH Zurich, CH-8093 Zurich, Switzerland.

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http://dx.doi.org/10.1021/bi2011338DOI Listing
October 2011

Design of chemical libraries with potentially bioactive molecules applying a maximum common substructure concept.

Mol Divers 2010 May 15;14(2):401-8. Epub 2009 Aug 15.

FMP Leibniz Institut für Molekulare Pharmakologie, Robert-Roessle Strasse 10, 13125, Berlin, Germany.

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http://dx.doi.org/10.1007/s11030-009-9187-zDOI Listing
May 2010

[Quitting hash. The readiness for behaviour change among cannabis users in Switzerland].

Int J Public Health 2007 ;52(4):233-41

Schweizerische Fachstelle für Alkohol- und andere Drogenprobleme SFA, Lausanne.

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January 2008

A simple selection strategy for evolving highly efficient enzymes.

Nat Biotechnol 2007 Oct 16;25(10):1145-7. Epub 2007 Sep 16.

Laboratory of Organic Chemistry, ETH Zurich, Hönggerberg HCI F 339, CH-8093 Zurich, Switzerland.

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http://dx.doi.org/10.1038/nbt1341DOI Listing
October 2007

A comparative study on dual patients with affective disorder.

J Affect Disord 2007 Sep 30;102(1-3):109-14. Epub 2007 Jan 30.

Department of Psychiatry, Burghölzli Hospital, University of Zurich, Lenggstrasse 31, CH-8032 Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.jad.2006.12.014DOI Listing
September 2007

Metabolic engineering of a genetic selection system with tunable stringency.

Proc Natl Acad Sci U S A 2007 Aug 22;104(35):13907-12. Epub 2007 Aug 22.

Laboratory of Organic Chemistry, ETH Zurich, CH-8093 Zurich, Switzerland.

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http://dx.doi.org/10.1073/pnas.0705379104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1955800PMC
August 2007

Prevalence of mental disorders in the Zurich Cohort Study: a twenty year prospective study.

Epidemiol Psichiatr Soc 2005 Apr-Jun;14(2):68-76

Zürich University Psychiatric Hospital, Zürich, Switzerland.

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August 2005

Longitudinal trajectories of depression and anxiety in a prospective community study: the Zurich Cohort Study.

Arch Gen Psychiatry 2003 Oct;60(10):993-1000

Mood and Anxiety Disorders Program, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1001/archpsyc.60.9.993DOI Listing
October 2003

Rubredoxins involved in alkane oxidation.

J Bacteriol 2002 Mar;184(6):1722-32

Institute of Biotechnology, Swiss Federal Institute of Technology, ETH-Hönggerberg, CH-8093 Zürich, Switzerland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC134906PMC
http://dx.doi.org/10.1128/jb.184.6.1722-1732.2002DOI Listing
March 2002