Publications by authors named "Martin M Matzuk"

100Publications

Synthesis of 5-substituted tetrazoles DNA-conjugated nitrile.

Org Biomol Chem 2020 Nov 11. Epub 2020 Nov 11.

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1039/d0ob02021dDOI Listing
November 2020

Solution-Phase Fmoc-Based Peptide Synthesis for DNA-Encoded Chemical Libraries: Reaction Conditions, Protecting Group Strategies, and Pitfalls.

ACS Comb Sci 2020 Oct 19. Epub 2020 Oct 19.

Department of Pharmacology and Chemical Biology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030 United States.

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http://dx.doi.org/10.1021/acscombsci.0c00144DOI Listing
October 2020

A special issue on contraceptive development: past, present, and future.

Biol Reprod 2020 08;103(2):145-146

The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.

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http://dx.doi.org/10.1093/biolre/ioaa120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401340PMC
August 2020

Discovery of potent thrombin inhibitors from a protease-focused DNA-encoded chemical library.

Proc Natl Acad Sci U S A 2020 07 8;117(29):16782-16789. Epub 2020 Jul 8.

Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX 77030

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http://dx.doi.org/10.1073/pnas.2005447117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382296PMC
July 2020

Tmprss12 is required for sperm motility and uterotubal junction migration in mice†.

Biol Reprod 2020 08;103(2):254-263

Department of Experimental Genome Research, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.

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http://dx.doi.org/10.1093/biolre/ioaa060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401031PMC
August 2020

CIB4 is essential for the haploid phase of spermatogenesis in mice†.

Biol Reprod 2020 08;103(2):235-243

Department of Experimental Genome Research, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.

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http://dx.doi.org/10.1093/biolre/ioaa059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401386PMC
August 2020

Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm-oocyte fusion in mice.

Proc Natl Acad Sci U S A 2020 05 11;117(21):11493-11502. Epub 2020 May 11.

Research Institute for Microbial Diseases, Osaka University, 565-0871 Osaka, Japan;

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http://dx.doi.org/10.1073/pnas.1922650117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261011PMC
May 2020

Prss55 but not Prss51 is required for male fertility in mice†.

Biol Reprod 2020 08;103(2):223-234

Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.

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http://dx.doi.org/10.1093/biolre/ioaa041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401375PMC
August 2020

Spermatozoa lacking Fertilization Influencing Membrane Protein (FIMP) fail to fuse with oocytes in mice.

Proc Natl Acad Sci U S A 2020 04 15;117(17):9393-9400. Epub 2020 Apr 15.

Research Institute for Microbial Diseases, Osaka University, Suita, 565-0871 Osaka, Japan;

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http://dx.doi.org/10.1073/pnas.1917060117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196805PMC
April 2020

C-N Coupling of DNA-Conjugated (Hetero)aryl Bromides and Chlorides for DNA-Encoded Chemical Library Synthesis.

Bioconjug Chem 2020 03 21;31(3):770-780. Epub 2020 Feb 21.

Center for Drug Discovery, Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas 77030, United States.

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http://dx.doi.org/10.1021/acs.bioconjchem.9b00863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7086399PMC
March 2020

Homogeneous and Functional Group Tolerant Ring-Closing Metathesis for DNA-Encoded Chemical Libraries.

ACS Comb Sci 2020 02 21;22(2):80-88. Epub 2020 Jan 21.

Center for Drug Discovery and Department of Pathology and Immunology , Baylor College of Medicine , One Baylor Plaza , Houston , Texas 77030 , United States.

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http://dx.doi.org/10.1021/acscombsci.9b00199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014401PMC
February 2020

Mouse t-complex protein 11 is important for progressive motility in sperm†.

Biol Reprod 2020 04;102(4):852-862

Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA.

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http://dx.doi.org/10.1093/biolre/ioz226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7124965PMC
April 2020

Palladium-Catalyzed Hydroxycarbonylation of (Hetero)aryl Halides for DNA-Encoded Chemical Library Synthesis.

Bioconjug Chem 2019 08 31;30(8):2209-2215. Epub 2019 Jul 31.

Center for Drug Discovery, Department of Pathology and Immunology , Baylor College of Medicine , Houston , Texas 77030 , United States.

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http://dx.doi.org/10.1021/acs.bioconjchem.9b00447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6706801PMC
August 2019

Reply to Liu et al.: ALK5-mediated tumor suppressor signaling through SMAD2 and SMAD3 in the uterus.

Proc Natl Acad Sci U S A 2019 05;116(19):9166-9167

Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030;

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http://dx.doi.org/10.1073/pnas.1904354116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511039PMC
May 2019

Multistep Synthesis of 1,2,4-Oxadiazoles via DNA-Conjugated Aryl Nitrile Substrates.

Bioconjug Chem 2019 05 10;30(5):1304-1308. Epub 2019 Apr 10.

Center for Drug Discovery, Department of Pathology and Immunology , Baylor College of Medicine , Houston , Texas 77030 , United States.

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http://dx.doi.org/10.1021/acs.bioconjchem.9b00188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786255PMC
May 2019

A Mild, DNA-Compatible Nitro Reduction Using B(OH).

Org Lett 2019 04 12;21(7):2194-2199. Epub 2019 Mar 12.

Center for Drug Discovery , Baylor College of Medicine , Houston , Texas 77030 , United States.

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http://pubs.acs.org/doi/10.1021/acs.orglett.9b00497
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http://dx.doi.org/10.1021/acs.orglett.9b00497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457042PMC
April 2019

Quantitative Comparison of Enrichment from DNA-Encoded Chemical Library Selections.

ACS Comb Sci 2019 02 23;21(2):75-82. Epub 2019 Jan 23.

FORMA Therapeutics Inc. , 500 Arsenal Street, Suite 100 , Watertown , Massachusetts 02472 , United States.

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http://pubs.acs.org/doi/10.1021/acscombsci.8b00116
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http://dx.doi.org/10.1021/acscombsci.8b00116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372980PMC
February 2019

Activin-like kinase 5 (ALK5) inactivation in the mouse uterus results in metastatic endometrial carcinoma.

Proc Natl Acad Sci U S A 2019 02 17;116(9):3883-3892. Epub 2019 Jan 17.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030;

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http://dx.doi.org/10.1073/pnas.1806838116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397539PMC
February 2019

Uterine double-conditional inactivation of and in mice causes endometrial dysregulation, infertility, and uterine cancer.

Proc Natl Acad Sci U S A 2019 02 16;116(9):3873-3882. Epub 2019 Jan 16.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030;

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http://dx.doi.org/10.1073/pnas.1806862116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397514PMC
February 2019

Dynamic cytoplasmic projections connect mammalian spermatogonia .

Development 2018 08 13;145(15). Epub 2018 Aug 13.

Department of Anatomy and Cell Biology at East Carolina University, Greenville, NC 27834, USA

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http://dx.doi.org/10.1242/dev.161323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110146PMC
August 2018

Systematic Identification of Druggable Epithelial-Stromal Crosstalk Signaling Networks in Ovarian Cancer.

J Natl Cancer Inst 2019 03;111(3):272-282

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1093/jnci/djy097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410941PMC
March 2019

In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells.

Nat Commun 2017 06 12;8:15680. Epub 2017 Jun 12.

Center for Stem Cell Biology and Regenerative Medicine, Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China.

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http://dx.doi.org/10.1038/ncomms15680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472783PMC
June 2017

Reconstitution of the oocyte nucleolus in mice through a single nucleolar protein, NPM2.

J Cell Sci 2017 Jul 9;130(14):2416-2429. Epub 2017 Jun 9.

Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1242/jcs.195875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139372PMC
July 2017

Follistatin is critical for mouse uterine receptivity and decidualization.

Proc Natl Acad Sci U S A 2017 06 30;114(24):E4772-E4781. Epub 2017 May 30.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030;

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http://dx.doi.org/10.1073/pnas.1620903114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474784PMC
June 2017

BMP7 Induces Uterine Receptivity and Blastocyst Attachment.

Endocrinology 2017 04;158(4):979-992

Departments of Pathology and Immunology, Baylor College of Medicine, Houston, TX.

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http://dx.doi.org/10.1210/en.2016-1629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460793PMC
April 2017

Identification of KIAA1210 as a novel X-chromosome-linked protein that localizes to the acrosome and associates with the ectoplasmic specialization in testes.

Biol Reprod 2017 02;96(2):469-477

Departments of Pathology and Immunology, Molecular and Cellular Biology, Molecular and Human Genetics, and Pharmacology, Center for Drug Discovery, and Center for Reproductive Medicine, Baylor College of Medicine, Houston, Texas, USA.

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http://dx.doi.org/10.1095/biolreprod.116.145458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819839PMC
February 2017

The TGF-β Family in the Reproductive Tract.

Cold Spring Harb Perspect Biol 2017 Oct 3;9(10). Epub 2017 Oct 3.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas 77030.

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http://dx.doi.org/10.1101/cshperspect.a022251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554737PMC
October 2017

Epithelialization of mouse ovarian tumor cells originating in the fallopian tube stroma.

Oncotarget 2016 Oct;7(40):66077-66086

Department of Obstetrics/Gynecology and Reproductive Biology, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.18632/oncotarget.11808DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323216PMC
October 2016

MRG15 is required for pre-mRNA splicing and spermatogenesis.

Proc Natl Acad Sci U S A 2016 09 29;113(37):E5408-15. Epub 2016 Aug 29.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030; Center for Reproductive Medicine, Baylor College of Medicine, Houston, TX 77030; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030; Department of Pharmacology, Baylor College of Medicine, Houston, TX 77030; Center for Drug Discovery, Baylor College of Medicine, Houston, TX 77030

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http://dx.doi.org/10.1073/pnas.1611995113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027415PMC
September 2016

Pentraxin 3 deletion aggravates allergic inflammation through a T17-dominant phenotype and enhanced CD4 T-cell survival.

J Allergy Clin Immunol 2017 Mar 26;139(3):950-963.e9. Epub 2016 Jul 26.

Department of Immunology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.04.063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317853PMC
March 2017

Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice.

Proc Natl Acad Sci U S A 2016 07 29;113(28):7704-10. Epub 2016 Jun 29.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030; Center for Reproductive Medicine, Baylor College of Medicine, Houston, TX 77030; Center for Drug Discovery, Baylor College of Medicine, Houston, TX 77030; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030; Department of Pharmacology, Baylor College of Medicine, Houston, TX 77030

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http://dx.doi.org/10.1073/pnas.1608458113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948324PMC
July 2016

Uterine ALK3 is essential during the window of implantation.

Proc Natl Acad Sci U S A 2016 Jan 31;113(3):E387-95. Epub 2015 Dec 31.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030; Center for Reproductive Medicine, Baylor College of Medicine, Houston, TX 77030; Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030; Department of Pharmacology, Baylor College of Medicine, Houston, TX 77030; Center for Drug Discovery, Baylor College of Medicine, Houston, TX 77030

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http://dx.doi.org/10.1073/pnas.1523758113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725477PMC
January 2016

DEVELOPMENTAL BIOLOGY. Toward a rapid and reversible male pill.

Science 2015 Oct 22;350(6259):385-6. Epub 2015 Oct 22.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA. Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA. Center for Reproductive Medicine, Baylor College of Medicine, Houston, TX 77030, USA. Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA. Department of Pharmacology, Baylor College of Medicine, Houston, TX 77030, USA. Center for Drug Discovery, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1126/science.aad4425DOI Listing
October 2015

Poreless eggshells.

J Clin Invest 2015 Nov 20;125(11):4005-7. Epub 2015 Oct 20.

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https://www.jci.org/articles/view/84692
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http://dx.doi.org/10.1172/JCI84692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639988PMC
November 2015

Uterine Activin-Like Kinase 4 Regulates Trophoblast Development During Mouse Placentation.

Mol Endocrinol 2015 Dec 20;29(12):1684-93. Epub 2015 Oct 20.

Departments of Pathology and Immunology (J.P., P.T.F., D.M., M.M.M.), Molecular and Human Genetics (J.P., P.T.F., M.M.M.), Molecular and Cellular Biology (M.M.M.), and Pharmacology (M.M.M.), Centers for Reproductive Medicine (M.M.M.) and Drug Discovery (P.T.F., D.M., M.M.M.), Baylor College of Medicine, Houston, Texas 77030; Department of Pathology (C.C.), New York University School of Medicine, New York, New York 10016; and Departments of Pathology (G.H.S.) and Otolaryngology/Head and Neck Surgery (G.H.S.), Columbia University College of Physicians and Surgeons, New York, New York 10032.

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http://dx.doi.org/10.1210/me.2015-1048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664232PMC
December 2015

Uterine activin receptor-like kinase 5 is crucial for blastocyst implantation and placental development.

Proc Natl Acad Sci U S A 2015 Sep 24;112(36):E5098-107. Epub 2015 Aug 24.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030; Center for Drug Discovery, Baylor College of Medicine, Houston, TX 77030; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030; Department of Pharmacology, Baylor College of Medicine, Houston, TX 77030

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http://www.pnas.org/lookup/doi/10.1073/pnas.1514498112
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http://dx.doi.org/10.1073/pnas.1514498112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568667PMC
September 2015

Insights Into SMAD4 Loss in Pancreatic Cancer From Inducible Restoration of TGF-β Signaling.

Mol Endocrinol 2015 Oct 18;29(10):1440-53. Epub 2015 Aug 18.

Departments of Molecular and Human Genetics (P.T.F., M.M.M.), Pathology and Immunology (P.T.F., M.M.M.), Molecular and Cellular Biology (M.M.M.), Pharmacology (M.M.M.), and Medicine (C.J.C.); the Center for Drug Discovery (P.T.F., M.M.M.); and the Dan L. Duncan Cancer Center (P.T.F., C.J.C., M.M.M.), Baylor College of Medicine, Houston, Texas 77030.

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http://dx.doi.org/10.1210/me.2015-1102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588735PMC
October 2015

Recurrent DICER1 hotspot mutations in endometrial tumours and their impact on microRNA biogenesis.

J Pathol 2015 Oct 6;237(2):215-25. Epub 2015 Jul 6.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1002/path.4569DOI Listing
October 2015

Lineage specification of ovarian theca cells requires multicellular interactions via oocyte and granulosa cells.

Nat Commun 2015 Apr 28;6:6934. Epub 2015 Apr 28.

Reproductive and Developmental Biology Laboratory, National Institute of Environmental Health Sciences, Durham, North Carolina, USA.

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http://dx.doi.org/10.1038/ncomms7934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413950PMC
April 2015

The ovary is an alternative site of origin for high-grade serous ovarian cancer in mice.

Endocrinology 2015 Jun 27;156(6):1975-81. Epub 2015 Mar 27.

Departments of Pathology and Immunology (J.K., L.M., M.M.M.), Molecular and Cellular Biology (M.M.M.), Molecular and Human Genetics (M.M.M.), and Pharmacology (M.M.M.); Center for Drug Discovery (M.M.M.); Dan L. Duncan Cancer Center (J.K., M.M.M.), and Center for Reproductive Medicine (J.K., M.M.M.), Baylor College of Medicine; and Department of Pathology and Genomic Medicine (D.M.C.), Houston Methodist and Weill Medical College of Cornell University, Houston, Texas 77030.

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http://dx.doi.org/10.1210/en.2014-1977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5393339PMC
June 2015

Recurrent BCAM-AKT2 fusion gene leads to a constitutively activated AKT2 fusion kinase in high-grade serous ovarian carcinoma.

Proc Natl Acad Sci U S A 2015 Mar 2;112(11):E1272-7. Epub 2015 Mar 2.

Departments of Pathology & Immunology, Molecular and Cellular Biology, Dan L. Duncan Cancer Center, and Center for Drug Discovery, Baylor College of Medicine, Houston, TX 77030

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http://dx.doi.org/10.1073/pnas.1501735112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371965PMC
March 2015

Metabolomic serum profiling detects early-stage high-grade serous ovarian cancer in a mouse model.

J Proteome Res 2015 Feb 16;14(2):917-27. Epub 2015 Jan 16.

School of Chemistry & Biochemistry, Georgia Institute of Technology , 901 Atlantic Drive NW, Atlanta, Georgia 30332, United States.

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http://pubs.acs.org/doi/10.1021/pr5009948
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http://dx.doi.org/10.1021/pr5009948DOI Listing
February 2015

Functional analysis of miR-34c as a putative tumor suppressor in high-grade serous ovarian cancer.

Biol Reprod 2014 Nov 1;91(5):113. Epub 2014 Oct 1.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas Department of Pharmacology, Baylor College of Medicine, Houston, Texas Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas

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http://dx.doi.org/10.1095/biolreprod.114.121988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366460PMC
November 2014

Amino acid 72 of mouse and human GDF9 mature domain is responsible for altered homodimer bioactivities but has subtle effects on GDF9:BMP15 heterodimer activities.

Biol Reprod 2014 Dec 24;91(6):142. Epub 2014 Sep 24.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas Deparment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas Department of Pharmacology, Baylor College of Medicine, Houston, Texas Center for Drug Discovery, Baylor College of Medicine, Houston, Texas Center for Reproductive Medicine, Baylor College of Medicine, Houston, Texas

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http://dx.doi.org/10.1095/biolreprod.114.123158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434983PMC
December 2014

Activation of neuronal gene expression by the JMJD3 demethylase is required for postnatal and adult brain neurogenesis.

Cell Rep 2014 Sep 28;8(5):1290-9. Epub 2014 Aug 28.

Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA; Veterans Affairs Medical Center, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.07.060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201382PMC
September 2014

Disrupting the male germ line to find infertility and contraception targets.

Ann Endocrinol (Paris) 2014 May 30;75(2):101-8. Epub 2014 Apr 30.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, USA; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA; Department of Pharmacology, Baylor College of Medicine, Houston, TX, USA; Center for Drug Discovery, Baylor College of Medicine, Houston, TX, USA; Center for Reproductive Medicine, Baylor College of Medicine, Houston, TX, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00034266140004
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http://dx.doi.org/10.1016/j.ando.2014.04.006DOI Listing
May 2014

Genetics of male fertility.

Methods Mol Biol 2014 ;1154:25-37

Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.

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http://dx.doi.org/10.1007/978-1-4939-0659-8_2DOI Listing
December 2014

CDKN2D-WDFY2 is a cancer-specific fusion gene recurrent in high-grade serous ovarian carcinoma.

PLoS Genet 2014 Mar 27;10(3):e1004216. Epub 2014 Mar 27.

Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas, United States of America; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas, United States of America; Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967933PMC
March 2014

Activin-like kinase 2 functions in peri-implantation uterine signaling in mice and humans.

PLoS Genet 2013 Nov 14;9(11):e1003863. Epub 2013 Nov 14.

Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, United States of America ; Departments of Pathology & Immunology, Baylor College of Medicine, Houston, Texas, United States of America ; Center for Reproductive Medicine, Baylor College of Medicine, Houston, Texas, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1003863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828128PMC
November 2013

H3K27 demethylase, JMJD3, regulates fragmentation of spermatogonial cysts.

PLoS One 2013 15;8(8):e72689. Epub 2013 Aug 15.

Departments of Pathology & Immunology, Baylor College of Medicine, Houston, Texas, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744460PMC
September 2014

GASZ promotes germ cell derivation from embryonic stem cells.

Stem Cell Res 2013 Sep 4;11(2):845-60. Epub 2013 Jun 4.

Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China.

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http://dx.doi.org/10.1016/j.scr.2013.05.012DOI Listing
September 2013

BMPR2 is required for postimplantation uterine function and pregnancy maintenance.

J Clin Invest 2013 Jun 8;123(6):2539-50. Epub 2013 May 8.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1172/JCI65710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668851PMC
June 2013

UBE2B mRNA alterations are associated with severe oligozoospermia in infertile men.

Mol Hum Reprod 2013 Jun 31;19(6):388-94. Epub 2013 Jan 31.

Department of OBGYN, School of Medicine, University of Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1093/molehr/gat008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655768PMC
June 2013

Endothelial pentraxin 3 contributes to murine ischemic acute kidney injury.

Kidney Int 2012 Dec 15;82(11):1195-207. Epub 2012 Aug 15.

Department of Internal Medicine (Nephrology), University of Texas Southwestern Medical Center, Dallas, Texas 75390-8856, USA.

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http://dx.doi.org/10.1038/ki.2012.268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499641PMC
December 2012

Role of satellite cells versus myofibers in muscle hypertrophy induced by inhibition of the myostatin/activin signaling pathway.

Proc Natl Acad Sci U S A 2012 Aug 6;109(35):E2353-60. Epub 2012 Aug 6.

Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1073/pnas.1206410109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435227PMC
August 2012

Activin B regulates islet composition and islet mass but not whole body glucose homeostasis or insulin sensitivity.

Am J Physiol Endocrinol Metab 2012 Sep 26;303(5):E587-96. Epub 2012 Jun 26.

Pioneer Valley Life Science Institute, University of Massachusetts-Amherst, Springfield MA, USA.

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http://dx.doi.org/10.1152/ajpendo.00177.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468507PMC
September 2012

Characterization of spermatogonial stem cells lacking intercellular bridges and genetic replacement of a mutation in spermatogonial stem cells.

PLoS One 2012 13;7(6):e38914. Epub 2012 Jun 13.

Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374785PMC
December 2012

Genetics of mammalian reproduction: modeling the end of the germline.

Annu Rev Physiol 2012 ;74:503-28

Department of Pathology, Baylor College of Medicine, Houston, Texas 77030, USA.

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June 2012

High-grade serous ovarian cancer arises from fallopian tube in a mouse model.

Proc Natl Acad Sci U S A 2012 Mar 13;109(10):3921-6. Epub 2012 Feb 13.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309733PMC
March 2012

Transforming growth factor β receptor type 1 is essential for female reproductive tract integrity and function.

PLoS Genet 2011 Oct 20;7(10):e1002320. Epub 2011 Oct 20.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197682PMC
October 2011

Connective tissue growth factor is required for normal follicle development and ovulation.

Mol Endocrinol 2011 Oct 25;25(10):1740-59. Epub 2011 Aug 25.

Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1210/me.2011-1045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182424PMC
October 2011

Germ cell intercellular bridges.

Cold Spring Harb Perspect Biol 2011 Aug 1;3(8):a005850. Epub 2011 Aug 1.

Department of Radiation Oncology, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1101/cshperspect.a005850DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140685PMC
August 2011

Reproductive tract function and dysfunction in women.

Nat Rev Endocrinol 2011 May 24;7(9):517-25. Epub 2011 May 24.

Department of Pathology, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.1038/nrendo.2011.79DOI Listing
May 2011

Minireview: The roles of small RNA pathways in reproductive medicine.

Mol Endocrinol 2011 Aug 5;25(8):1257-79. Epub 2011 May 5.

Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1210/me.2011-0099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146245PMC
August 2011

Functional microRNA involved in endometriosis.

Mol Endocrinol 2011 May 24;25(5):821-32. Epub 2011 Mar 24.

Department of Obstetrics and Gynecology, Baylor College of Medicine, 1709 Dryden Drive, Suite 1100, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1210/me.2010-0371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3082329PMC
May 2011

Identification and characterization of RBM44 as a novel intercellular bridge protein.

PLoS One 2011 Feb 25;6(2):e17066. Epub 2011 Feb 25.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045441PMC
February 2011

Analysis of microRNA expression in the prepubertal testis.

PLoS One 2010 Dec 29;5(12):e15317. Epub 2010 Dec 29.

Department of Pathology, Baylor College of Medicine, Houston, Texas, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012074PMC
December 2010

Regulation of muscle mass by follistatin and activins.

Mol Endocrinol 2010 Oct 1;24(10):1998-2008. Epub 2010 Sep 1.

Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954636PMC
October 2010

MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing.

PLoS Biol 2010 Aug 17;8(8). Epub 2010 Aug 17.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America.

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http://dx.doi.org/10.1371/journal.pbio.1000453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923083PMC
August 2010

Defective gonadotropin-dependent ovarian folliculogenesis and granulosa cell gene expression in inhibin-deficient mice.

Endocrinology 2010 Oct 25;151(10):4994-5006. Epub 2010 Aug 25.

Department of Pathology and Immunology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1210/en.2010-0428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946151PMC
October 2010

Absence of inhibin alpha and retinoblastoma protein leads to early sertoli cell dysfunction.

PLoS One 2010 Jul 27;5(7):e11797. Epub 2010 Jul 27.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910728PMC
July 2010

Genetic evidence that SMAD2 is not required for gonadal tumor development in inhibin-deficient mice.

Reprod Biol Endocrinol 2010 Jun 21;8:69. Epub 2010 Jun 21.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1186/1477-7827-8-69DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903601PMC
June 2010

Local signalling environments and human male infertility: what we can learn from mouse models.

Expert Rev Mol Med 2010 May 11;12:e15. Epub 2010 May 11.

Department of Pathology, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1017/S1462399410001468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056269PMC
May 2010