Martin Lepage

Martin Lepage

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Martin Lepage

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Increased precision in the intravascular arterial input function with flow compensation.

Magn Reson Med 2019 Nov 22;82(5):1782-1795. Epub 2019 Jun 22.

Centre d'imagerie moléculaire de Sherbrooke, Département de médecine nucléaire et radiobiologie, Université de Sherbrooke, 3001 12e Avenue Nord, Sherbrooke, Québec, Canada.

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http://dx.doi.org/10.1002/mrm.27877DOI Listing
November 2019

Using proton magnetic resonance spectroscopic imaging to study glutamatergic alterations in patients with schizophrenia: A systematic review.

Schizophr Res 2019 Aug 1;210:13-20. Epub 2019 Jul 1.

Cerebral Imaging Centre, Douglas Mental Health University Institute, Montreal, QC, Canada; Department of Psychiatry, McGill University, Montreal, QC, Canada; Department of Biomedical Engineering, McGill University, Montreal, QC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2019.06.011DOI Listing
August 2019

In Vivo Endomicroscopy of Lung Injury and Repair in ARDS: Potential Added Value to Current Imaging.

J Clin Med 2019 Aug 11;8(8). Epub 2019 Aug 11.

Sherbrooke Molecular Imaging Center (CIMS), Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.

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http://dx.doi.org/10.3390/jcm8081197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723156PMC
August 2019

Identifying schizophrenia subgroups using clustering and supervised learning.

Schizophr Res 2019 Aug 24. Epub 2019 Aug 24.

Biological & Biomedical Engineering, McGill University, 845 Sherbrooke Street West, Montreal, Quebec H3A 0G4, Canada; Douglas Mental Health University Institute, 6875 Boulevard LaSalle, Verdun, QC H4H 1R3, Canada; Department of Psychiatry, McGill University, 845 Sherbrooke Street West, Montreal, Quebec H3A 0G4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2019.05.044DOI Listing
August 2019

Intersection of verbal memory and expressivity on cortical contrast and thickness in first episode psychosis.

Psychol Med 2019 Aug 28:1-14. Epub 2019 Aug 28.

Department of Psychiatry, McGill University, Verdun, Canada.

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http://dx.doi.org/10.1017/S0033291719002071DOI Listing
August 2019

A ketogenic drink improves brain energy and some measures of cognition in mild cognitive impairment.

Alzheimers Dement 2019 May 23;15(5):625-634. Epub 2019 Apr 23.

Research Center on Aging, CIUSSS de l'Estrie - CHUS, Sherbrooke, Quebec, Canada; Department of Pharmacology and Physiology, Université de Sherbrooke, Sherbrooke, Quebec, Canada; Department of Medicine, Université de Sherbrooke, Sherbrooke, Quebec, Canada.

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http://dx.doi.org/10.1016/j.jalz.2018.12.017DOI Listing
May 2019

Cognitive capacity similarly predicts insight into symptoms in first- and multiple-episode psychosis.

Schizophr Res 2019 Apr 1;206:236-243. Epub 2018 Dec 1.

Douglas Mental Health University Institute, 6875 LaSalle Blvd, Verdun, Quebec H4H 1R3, Canada; Department of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, Quebec H3A 1A1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2018.11.013DOI Listing
April 2019

The role of illness engulfment in the association between insight and depressive symptomatology in schizophrenia.

J Psychiatr Res 2019 Apr 11;111:1-7. Epub 2019 Jan 11.

Douglas Mental Health University Institute, 6875 LaSalle Boulevard, Montreal, QC, H4H 1R3, Montreal, Canada; Department of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, QC, H3A 1A1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2018.11.001DOI Listing
April 2019

Structural Associations of Cortical Contrast and Thickness in First Episode Psychosis.

Cereb Cortex 2019 Mar 7. Epub 2019 Mar 7.

McGill Centre for Integrative Neuroscience, McGill University, Montreal, Canada.

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http://dx.doi.org/10.1093/cercor/bhz040DOI Listing
March 2019

Determination of a pharmacokinetic model for [C]-acetate in brown adipose tissue.

EJNMMI Res 2019 Mar 27;9(1):31. Epub 2019 Mar 27.

Faculté de médecine et des sciences de la santé, Université de Sherbrooke, 3001 12th Avenue North, Sherbrooke, QC, J1H 5N4, Canada.

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http://dx.doi.org/10.1186/s13550-019-0497-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437247PMC
March 2019

Clarifying associations between cortical thickness, subcortical structures, and a comprehensive assessment of clinical insight in enduring schizophrenia.

Schizophr Res 2019 02 24;204:245-252. Epub 2018 Aug 24.

Douglas Mental Health University Institute, McGill University, Montreal, Canada; Department of Psychology, McGill University, Montreal, Canada; Department of Psychiatry, McGill University, Montreal, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2018.08.024DOI Listing
February 2019

Progress of negative symptoms over the initial 5 years of a first episode of psychosis.

Psychol Med 2019 01 14;49(1):66-74. Epub 2018 Mar 14.

Department of Psychiatry,McGill University,Douglas Mental Health University Institute; Prevention and Early Intervention Program for Psychosis (PEPP-Montreal),Montreal,QC,Canada.

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http://dx.doi.org/10.1017/S003329171800048XDOI Listing
January 2019

Head motion: the dirty little secret of neuroimaging in psychiatry

J Psychiatry Neurosci 2019 Jan;44(1):62-68

From the McGill Centre for Integrative Neuroscience, McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Que., Canada (Makowski, Evans); and the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Verdun, Que., Canada (Makowski, Lepage).

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http://dx.doi.org/10.1503/jpn.180022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306289PMC
January 2019

Links Between Metabolic and Structural Changes in the Brain of Cognitively Normal Older Adults: A 4-Year Longitudinal Follow-Up.

Front Aging Neurosci 2019 15;11:15. Epub 2019 Jan 15.

Research Center on Aging, Centre Intégré Universitaire de Santé et de Services Sociaux de l'Estrie (CIUSSS) de L'Estrie-Centre hospitalier Universitaire de Sherbrooke (CHUS), Sherbrooke, QC, Canada.

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http://dx.doi.org/10.3389/fnagi.2019.00015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384269PMC
January 2019

A NEET distinction: youths not in employment, education or training follow different pathways to illness and care in psychosis.

Soc Psychiatry Psychiatr Epidemiol 2018 Dec 9;53(12):1401-1411. Epub 2018 Aug 9.

Department of Psychiatry, McGill University, Montreal, Canada.

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http://dx.doi.org/10.1007/s00127-018-1565-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267132PMC
December 2018

Predictors of 'all-cause discontinuation' of initial oral antipsychotic medication in first episode psychosis.

Schizophr Res 2018 11 26;201:287-293. Epub 2018 Apr 26.

Department of Psychiatry, McGill University, Montréal, QC, Canada; Douglas Mental Health University Institute, Montreal, QC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2018.04.027DOI Listing
November 2018

Comparing cognitive clusters across first- and multiple-episode of psychosis.

Psychiatry Res 2018 11 30;269:707-718. Epub 2018 Aug 30.

Douglas Mental Health University Institute, Montreal, Quebec, Canada; Department of Psychiatry, McGill University, Montreal, Quebec, Canada; Prevention and Early Intervention Program for Psychoses, Douglas Mental Health University Institute, Montreal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2018.08.119DOI Listing
November 2018

A study on negative and depressive symptom prevalence in individuals at ultra-high risk for psychosis.

Early Interv Psychiatry 2018 10 21;12(5):900-906. Epub 2016 Sep 21.

Prevention and Early Intervention Program for Psychoses, Douglas Mental Health University Institute, Verdun, Canada.

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http://dx.doi.org/10.1111/eip.12386DOI Listing
October 2018

Diffusion MRI monitoring of specific structures in the irradiated rat brain.

Magn Reson Med 2018 10 9;80(4):1614-1625. Epub 2018 Feb 9.

Sherbrooke Molecular Imaging Center, Department of Nuclear Medicine and Radiobiology, Université de Sherbrooke, Sherbrooke, Québec, Canada.

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http://dx.doi.org/10.1002/mrm.27112DOI Listing
October 2018

The Prevalence of Negative Symptoms Across the Stages of the Psychosis Continuum.

Harv Rev Psychiatry 2019 Jan/Feb;27(1):15-32

From the Department of Psychiatry, McGill University, and Douglas Mental Health University Institute, Montreal.

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http://Insights.ovid.com/crossref?an=00023727-900000000-9995
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http://dx.doi.org/10.1097/HRP.0000000000000184DOI Listing
October 2018

Dimensions of insight in schizophrenia: Exploratory factor analysis of items from multiple self- and interviewer-rated measures of insight.

Schizophr Res 2018 09 10;199:319-325. Epub 2018 Mar 10.

Douglas Mental Health University Institute, 6875 LaSalle Boulevard, Verdun, Quebec H4H 1R3, Canada; Department of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, Quebec H3A 1A1, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09209964183013
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http://dx.doi.org/10.1016/j.schres.2018.02.055DOI Listing
September 2018

Pathways to functional outcomes following a first episode of psychosis: The roles of premorbid adjustment, verbal memory and symptom remission.

Aust N Z J Psychiatry 2018 08 17;52(8):793-803. Epub 2017 Dec 17.

1 Department of Psychiatry, McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.1177/0004867417747401DOI Listing
August 2018

Head motion: the dirty little secret of neuroimaging in psychiatry.

J Psychiatry Neurosci 2018 Aug 14;43(5):180022. Epub 2018 Aug 14.

From the McGill Centre for Integrative Neuroscience, McConnell Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montreal, Que., Canada (Makowski, Evans); and the Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Verdun, Que., Canada (Makowski, Lepage).

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http://dx.doi.org/10.1503/jpn.180022DOI Listing
August 2018

Evaluating accuracy of striatal, pallidal, and thalamic segmentation methods: Comparing automated approaches to manual delineation.

Neuroimage 2018 04 1;170:182-198. Epub 2017 Mar 1.

Douglas Mental Health University Institute, McGill University, Montreal, Canada; Department of Psychiatry, McGill University, Montreal, Canada; Department of Biological and Biomedical Engineering, McGill University, Montreal, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2017.02.069DOI Listing
April 2018

A longitudinal study of cognitive insight and cortical thickness in first-episode psychosis.

Schizophr Res 2018 03 29;193:251-260. Epub 2017 Jun 29.

Douglas Mental Health University Institute, Verdun, Québec, Canada; Prevention and Early Intervention Program for Psychoses, Douglas Mental Health University Institute, Verdun, Québec, Canada; Department of Psychiatry, McGill University, Montreal, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2017.06.048DOI Listing
March 2018

Strategy for Semantic Association Memory (SESAME) training: Effects on brain functioning in schizophrenia.

Psychiatry Res Neuroimaging 2018 01 25;271:50-58. Epub 2017 Oct 25.

Douglas Mental Health University Institute, Montréal, Canada; Department of psychiatry, McGill University, Montréal, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.pscychresns.2017.10.010DOI Listing
January 2018

Tumor Cell Invasion Induced by Radiation in Balb/C Mouse is Prevented by the Cox-2 Inhibitor NS-398.

Radiat Res 2017 12 28;188(6):605-614. Epub 2017 Sep 28.

a   Center for Research in Radiotherapy and.

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http://dx.doi.org/10.1667/RR14716.1DOI Listing
December 2017

The relative contributions of social cognition and self-reflectiveness to clinical insight in enduring schizophrenia.

Psychiatry Res 2017 12 28;258:116-123. Epub 2017 Sep 28.

Integrated Program in Neuroscience, McGill University, Montreal, Canada; Douglas Mental Health University Institute, Verdun, Canada; Department of Psychiatry, McGill University, Montreal, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2017.09.082DOI Listing
December 2017

Improving the evaluation of cardiac function in rats at 7T with denoising filters: a comparison study.

BMC Med Imaging 2017 Dec 19;17(1):62. Epub 2017 Dec 19.

Le2I, Faculté de Médecine, Université Bourgogne Franche-Comté, 7 Bld Jeanne d'Arc, 21079, Dijon Cedex, BP 87900, France.

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http://dx.doi.org/10.1186/s12880-017-0236-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735834PMC
December 2017

Understanding the continuum of radionecrosis and vascular disorders in the brain following gamma knife irradiation: An MRI study.

Magn Reson Med 2017 10 10;78(4):1420-1431. Epub 2016 Nov 10.

Sherbrooke Molecular Imaging Center, Department of Nuclear Medicine and Radiobiology, Université de Sherbrooke, Sherbrooke, Québec, Canada.

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http://dx.doi.org/10.1002/mrm.26546DOI Listing
October 2017

Prefrontal activity and impaired memory encoding strategies in schizophrenia.

J Psychiatr Res 2017 08 8;91:64-73. Epub 2017 Mar 8.

Douglas Mental Health University Institute, Montréal, Canada; Department of Psychiatry, McGill University, Montréal, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2017.02.024DOI Listing
August 2017

Determination of an Optimal Pharmacokinetic Model of F-FET for Quantitative Applications in Rat Brain Tumors.

J Nucl Med 2017 08 30;58(8):1278-1284. Epub 2017 Mar 30.

Centre d'imagerie moléculaire de Sherbrooke, Département de médecine nucléaire et radiobiologie, Université de Sherbrooke, Sherbrooke, Québec, Canada

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http://dx.doi.org/10.2967/jnumed.116.180612DOI Listing
August 2017

Polygenic Risk Score associated with specific symptom dimensions in first-episode psychosis.

Schizophr Res 2017 06 2;184:116-121. Epub 2016 Dec 2.

Douglas Mental Health University Institute, 6875 LaSalle Blvd, Verdun, Quebec H4H 1R3, Canada; Department of Psychiatry, McGill University, Ludmer Research & Training Building, 1033 Pine Ave. West, Montreal, Quebec H3A 1A1, Canada; Integrated Program in Neuroscience, McGill University, Room 141, Montreal Neurological Institute, 3801 University Street, Montreal, Quebec H3A 2B4, Canada; Department of Human Genetics, McGill University, Room N5-13, Stewart Biology Building, 1205 Dr. Penfield Ave., Montreal, Quebec H3A 1B1, Canada.

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http://dx.doi.org/10.1016/j.schres.2016.11.039DOI Listing
June 2017

Is cognitive insight relevant to functional capacity in schizophrenia?

Schizophr Res 2017 06 6;184:150-151. Epub 2017 Jan 6.

Prevention and Early Intervention Program for Psychoses (PEPP - Montreal), Douglas Mental Health University Institute, 6875 LaSalle Boulevard, Montreal, Quebec H4H 1R3, Canada; UQAM, Psychology Department, C.P. 8888 Succursale Centre-ville, Montreal, Quebec H3C 3P8, Canada; Department of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, Quebec H3A 1A1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2016.12.009DOI Listing
June 2017

Bipolar disorder risk gene modulates negative symptoms in schizophrenia: a neuroimaging genetics study.

J Psychiatry Neurosci 2017 05;42(3):172-180

From the Douglas Mental Health University Institute, Montreal, Que., Canada (Shenker, Sengupta, Joober, Malla, Chakravarty, Lepage); the Integrated Program in Neuroscience, McGill University, Montreal, Que., Canada (Shenker, Lepage); the Department of Psychiatry, McGill University, Montreal, Que., Canada (Sengupta, Joober, Malla, Chakravarty, Lepage); and the Department of Biomedical Engineering, McGill University, Montreal, Que., Canada (Chakravarty).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403662PMC
May 2017

Longitudinal trajectory of clinical insight and covariation with cortical thickness in first-episode psychosis.

J Psychiatr Res 2017 03 19;86:46-54. Epub 2016 Nov 19.

McGill Centre for Integrative Neuroscience, McGill University, Montréal, Québec, Canada; Prevention and Early Intervention Program for Psychoses, Douglas Mental Health University Institute, Verdun, Québec, Canada; Department of Psychiatry, McGill University, Montreal, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2016.11.008DOI Listing
March 2017

Duration of active psychosis and first-episode psychosis negative symptoms.

Early Interv Psychiatry 2017 02 13;11(1):63-71. Epub 2015 Jan 13.

Prevention and Early Intervention Program for Psychoses (PEPP-Montreal), Douglas Mental Health University Institute, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1111/eip.12217DOI Listing
February 2017

Smoking status and its relationship to demographic and clinical characteristics in first episode psychosis.

J Psychiatr Res 2017 Feb 27;85:83-90. Epub 2016 Oct 27.

Prevention and Early Intervention Program for Psychosis (PEPP-Montréal), Douglas Mental Health University Institute, 6875 Boulevard LaSalle, Verdun, QC, H4H 1R3, Canada; ACCESS Open Minds (A Pan-Canadian Youth Mental Health Network), Douglas Mental Health University Institute, 6875 Boulevard LaSalle, Verdun, QC, H4H 1R3, Canada; Department of Psychiatry, McGill University, 1033 Pine Avenue West, Montréal, QC, H3A 1A1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2016.10.022DOI Listing
February 2017

[Cognitive Behavioral Therapy and the Treatment of ADHD in Adults].

Sante Ment Que Spring 2016;41(1):291-311

Institut universitaire en santé mentale Douglas, Département de psychiatrie, Université McGill, Montréal.

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January 2017

Cognitive training of self-initiation of semantic encoding strategies in schizophrenia: A pilot study.

Neuropsychol Rehabil 2016 6;26(3):464-79. Epub 2015 Jul 6.

a Douglas Mental Health University Institute , Montreal , Canada.

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http://www.tandfonline.com/doi/full/10.1080/09602011.2015.10
Publisher Site
http://dx.doi.org/10.1080/09602011.2015.1045526DOI Listing
December 2016

Perinatal Arterial Ischemic Stroke Is Associated to Materno-Fetal Immune Activation and Intracranial Arteritis.

Int J Mol Sci 2016 Nov 25;17(12). Epub 2016 Nov 25.

Département de Pédiatrie, Université de Sherbrooke, Sherbrooke, QC J1H 5N4, Canada.

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http://dx.doi.org/10.3390/ijms17121980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187780PMC
November 2016

Age-related cortical thickness trajectories in first episode psychosis patients presenting with early persistent negative symptoms.

NPJ Schizophr 2016 24;2:16029. Epub 2016 Aug 24.

Integrated Program in Neuroscience, McGill University, Montreal, QC, Canada; Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, QC, Canada; Prevention and Early Intervention Program for Psychosis, Douglas Mental Health University Institute, McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.1038/npjschz.2016.29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007985PMC
September 2016

Manual-Protocol Inspired Technique for Improving Automated MR Image Segmentation during Label Fusion.

Front Neurosci 2016 19;10:325. Epub 2016 Jul 19.

Institute of Biomaterials and Biomedical Engineering, University of TorontoToronto, ON, Canada; Cerebral Imaging Centre, Douglas Mental Health University InstituteVerdun, QC, Canada; Department of Psychiatry, McGill UniversityMontreal, QC, Canada; Biological and Biomedical Engineering, McGill UniversityMontreal, QC, Canada.

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http://dx.doi.org/10.3389/fnins.2016.00325DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949270PMC
August 2016

Does the Beck Cognitive Insight Scale Predict Response to Cognitive Remediation in Schizophrenia?

Schizophr Res Treatment 2016 19;2016:6371856. Epub 2016 Jul 19.

Prevention and Early Intervention Program for Psychoses (PEPP-Montreal), Douglas Mental Health University Institute, 6875 LaSalle Boulevard, Montreal, QC, Canada H4H 1R3; Psychology Department, UQAM, C.P. 8888 Succursale Centre-ville, Montreal, QC, Canada H3C 3P8; Department of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, QC, Canada H3A 1A1.

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http://dx.doi.org/10.1155/2016/6371856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969539PMC
August 2016

Therapeutic effectiveness and tolerability of aripiprazole as initial choice of treatment in first episode psychosis in an early intervention service: A one-year outcome study.

Schizophr Res 2016 07 4;174(1-3):120-125. Epub 2016 May 4.

Department of Psychiatry, McGill University, Montréal, QC, Canada; Douglas Mental Health University Institute, Montreal, Canada.

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http://dx.doi.org/10.1016/j.schres.2016.04.036DOI Listing
July 2016

Comment on 'The influence of antioxidant THPC on the properties of polymer gel dosimeter'.

Phys Med Biol 2016 06 20;61(11):4342-3. Epub 2016 May 20.

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http://dx.doi.org/10.1088/0031-9155/61/11/4342DOI Listing
June 2016

MRI-Guided Derivation of the Input Function for PET Kinetic Modeling.

PET Clin 2016 Apr 26;11(2):193-202. Epub 2016 Jan 26.

Department of Nuclear Medicine and Radiobiology, Centre d'imagerie moléculaire de Sherbrooke (CIMS), Université de Sherbrooke, 3001, 12th Avenue North, Sherbrooke, Québec J1H 5N4, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cpet.2015.09.003DOI Listing
April 2016

Examining cortical thickness in male and female DWI offenders.

Neurosci Lett 2016 Apr 22;619:189-95. Epub 2016 Mar 22.

Douglas Hospital Research Centre, Montreal, Canada; Department of Psychiatry, McGill University, Montreal, Canada; Foster Addiction Rehabilitation Centre, St. Philippe de LaPrairie, Canada.

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http://dx.doi.org/10.1016/j.neulet.2016.03.034DOI Listing
April 2016

Dynamic endophenotypes and longitudinal trajectories: capturing changing aspects of development in early psychosis.

J Psychiatry Neurosci 2016 04;41(3):148-51

From PEPP-Montréal, Douglas Mental Health University Institute (Shah, Chakravarty, Joober, Lepage); Cerebral Imaging Centre, Douglas Mental Health University Institute (Chakravarty); and the Department of Psychiatry, McGill University (Shah, Chakravarty, Joober, Lepage), Montreal, Que., Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853205PMC
April 2016

Functional neural correlates of social approval in schizophrenia.

Soc Cogn Affect Neurosci 2016 Mar 29;11(3):445-57. Epub 2015 Oct 29.

Douglas Mental Health University Institute, Montréal, QC, Canada H4H 1R3

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http://dx.doi.org/10.1093/scan/nsv125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769627PMC
March 2016

Altered emotional modulation of associative memory in first episode schizophrenia: An fMRI study.

Schizophr Res Cogn 2016 Mar 17;3:26-32. Epub 2015 Dec 17.

Douglas Mental Health University Institute, 6875 Boul. LaSalle, Verdun, H4H 1R3, Canada.

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http://dx.doi.org/10.1016/j.scog.2015.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506707PMC
March 2016

The effect of second-generation antipsychotics on hippocampal volume in first episode of psychosis: longitudinal study.

BJPsych Open 2016 Mar 9;2(2):139-146. Epub 2016 Mar 9.

, PhD, Prevention and Early Intervention Program for Psychoses (PEPP - Montreal), Douglas Mental Health University Institute, Montreal, Canada; Department of Psychology, McGill University, Montreal, Canada; Department of Psychiatry, McGill University, Montreal, Canada; Integrated Program in Neuroscience, McGill University, Montreal, Canada.

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http://dx.doi.org/10.1192/bjpo.bp.115.002444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995582PMC
March 2016

Cortical thickness and low insight into symptoms in enduring schizophrenia.

Schizophr Res 2016 Jan 19;170(1):66-72. Epub 2015 Nov 19.

Douglas Mental Health University Institute, Canada; Dept. of Psychology, McGill University, Canada; Dept. of Psychiatry, McGill University, Canada.

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http://dx.doi.org/10.1016/j.schres.2015.10.016DOI Listing
January 2016

A comprehensive review on controls in molecular imaging: lessons from MMP-2 imaging.

Contrast Media Mol Imaging 2014 May-Jun;9(3):187-210

Centre d'imagerie moléculaire de Sherbrooke, Département de médecine nucléaire et radiobiologie, Université de Sherbrooke, Sherbrooke, QC, Canada.

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http://dx.doi.org/10.1002/cmmi.1555DOI Listing
November 2015

Cortical thinning in temporo-parietal junction (TPJ) in non-affective first-episode of psychosis patients with persistent negative symptoms.

PLoS One 2014 30;9(6):e101372. Epub 2014 Jun 30.

Prevention and Early Intervention Program for Psychoses (PEPP - Montreal), Douglas Mental Health University Institute, Montreal, Canada; Department of Psychology, McGill University, Montreal, Canada; Department of Neurology & Neurosurgery, McGill University, Montreal, Canada; Department of Psychiatry, McGill University, Montreal, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076331PMC
October 2015

Enhancing decision-making and cognitive impulse control with transcranial direct current stimulation (tDCS) applied over the orbitofrontal cortex (OFC): A randomized and sham-controlled exploratory study.

J Psychiatr Res 2015 Oct 17;69:27-34. Epub 2015 Jul 17.

Neuromodulation Research Clinic, Douglas Mental Health University Institute, Montréal, Québec, Canada; Depressive Disorders Program, Douglas Mental Health University Institute and McGill University, Montréal, Québec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2015.07.018DOI Listing
October 2015

Reduced hippocampal volume and hypothalamus-pituitary-adrenal axis function in first episode psychosis: evidence for sex differences.

Neuroimage Clin 2015 5;7:195-202. Epub 2014 Dec 5.

Department of Psychiatry, Prevention and Early Intervention Program for Psychosis, Douglas Mental Health University Institute, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.nicl.2014.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300007PMC
September 2015

Source retrieval is not properly differentiated from object retrieval in early schizophrenia: an fMRI study using virtual reality.

Neuroimage Clin 2015 13;7:336-46. Epub 2014 Aug 13.

Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Canada ; Prevention and Early Intervention Program for Psychoses, Douglas Mental Health University Institute, Verdun, Canada ; Department of Psychiatry, McGill University, Montreal, Canada.

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http://dx.doi.org/10.1016/j.nicl.2014.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297883PMC
September 2015

Cognitive deficits characterization using the CogState Research Battery in first-episode psychosis patients.

Schizophr Res Cogn 2015 Sep 6;2(3):140-145. Epub 2015 May 6.

Prevention and Early Intervention Program for Psychoses (PEPP - Montreal), Douglas Mental Health University Institute, 6875 LaSalle Boulevard, Montreal, (Quebec) H4H 1R3, Canada.

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http://dx.doi.org/10.1016/j.scog.2015.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779298PMC
September 2015

Relational Memory as a Possible Neurocognitive Marker of Schizophrenia.

JAMA Psychiatry 2015 Sep;72(9):946-7

Department of Psychology, McGill University, Montreal, Quebec, Canada3Douglas Mental Health University Institute, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1001/jamapsychiatry.2015.0488DOI Listing
September 2015

Investigation of white matter abnormalities in first episode psychosis patients with persistent negative symptoms.

Psychiatry Res 2015 Sep 2;233(3):402-8. Epub 2015 Jul 2.

Prevention and Early Intervention Program for Psychoses (PEPP-Montreal), Douglas Mental Health University Institute, Montreal, Quebec, Canada; Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada; Department of Psychiatry, McGill University, Montreal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.pscychresns.2015.06.017DOI Listing
September 2015

Smart imaging of acute lung injury: exploration of myeloperoxidase activity using in vivo endoscopic confocal fluorescence microscopy.

Am J Physiol Lung Cell Mol Physiol 2015 Sep 31;309(6):L543-51. Epub 2015 Jul 31.

Soins Intensifs Médicaux, Département de Médecine; Centre de Recherche Clinique du CHUS; Centre d'Imagerie Moléculaire de Sherbrooke; and

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http://dx.doi.org/10.1152/ajplung.00289.2014DOI Listing
September 2015

Cognitive insight in first-episode schizophrenia: further evidence for a role of the ventrolateral prefrontal cortex.

Schizophr Res 2015 Aug 23;166(1-3):65-8. Epub 2015 May 23.

Prevention and Early Intervention Program for Psychoses, Douglas Mental Health University Institute, Verdun, Canada; Department of Psychiatry, McGill University, Montreal, Canada; Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2015.05.009DOI Listing
August 2015

Clinical and functional implications of a history of childhood ADHD in first-episode psychosis.

Schizophr Res 2015 Jul 25;165(2-3):128-33. Epub 2015 Apr 25.

Douglas Mental Health University Institute, Research Institute, Boulevard LaSalle, H4H 1R3 Montreal, QC, Canada; McGill University, Faculty of Medicine, Department of Psychiatry, Ludmer Research & Training Building, 1033 Pine Avenue West, H3A 1A1 Montreal, QC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2015.03.031DOI Listing
July 2015

Judging Strangers' Trustworthiness is Associated with Theory of Mind Skills.

Front Psychiatry 2015 20;6:52. Epub 2015 Apr 20.

Department of Philosophy, McGill University , Montreal, QC , Canada ; Department of Psychiatry, Douglas Mental Health University Institute, McGill University , Montreal, QC , Canada.

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http://dx.doi.org/10.3389/fpsyt.2015.00052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4403288PMC
May 2015

Optimization of the reference region method for dual pharmacokinetic modeling using Gd-DTPA/MRI and (18) F-FDG/PET.

Magn Reson Med 2015 Feb 6;73(2):740-8. Epub 2014 Mar 6.

Centre d'imagerie moléculaire de Sherbrooke, Département de médecine nucléaire et radiobiologie, Université de Sherbrooke, Sherbrooke, Canada.

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http://dx.doi.org/10.1002/mrm.25151DOI Listing
February 2015

Multi-atlas segmentation of the whole hippocampus and subfields using multiple automatically generated templates.

Neuroimage 2014 Nov 29;101:494-512. Epub 2014 Apr 29.

Kimel Family Translational Imaging-Genetics Lab, Centre for Addiction and Mental Health, Toronto, ON, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada; Rotman Research Institute, Baycrest, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2014.04.054DOI Listing
November 2014

Functional magnetic resonance imaging study of external source memory and its relation to cognitive insight in non-clinical subjects.

Psychiatry Clin Neurosci 2014 Sep 13;68(9):683-91. Epub 2014 Apr 13.

Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Canada.

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http://dx.doi.org/10.1111/pcn.12177DOI Listing
September 2014

Overlapping patterns of neural activity for different forms of novelty in fMRI.

Front Hum Neurosci 2014 8;8:699. Epub 2014 Sep 8.

Douglas Mental Health University Institute, McGill University Montreal, QC, Canada.

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http://dx.doi.org/10.3389/fnhum.2014.00699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157542PMC
September 2014

The dorsolateral prefrontal cortex plays a role in self-initiated elaborative cognitive processing during episodic memory encoding: rTMS evidence.

PLoS One 2013 5;8(9):e73789. Epub 2013 Sep 5.

Department of Neurology and Neurosurgery, Douglas Mental Health University Institute, McGill University, Montreal, Quebec, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764025PMC
July 2014

Brain glucose and acetoacetate metabolism: a comparison of young and older adults.

Neurobiol Aging 2014 Jun 1;35(6):1386-95. Epub 2013 Dec 1.

Research Center on Aging, Université de Sherbrooke, Sherbrooke, Quebec, Canada; Department of Physiology and Biophysics, Université de Sherbrooke, Sherbrooke, Quebec, Canada; Department of Medicine, Université de Sherbrooke, Sherbrooke, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2013.11.027DOI Listing
June 2014

Arterial input function sampling without surgery in rats for positron emission tomography molecular imaging.

Nucl Med Commun 2014 Jun;35(6):666-76

Department of Nuclear Medicine and Radiobiology, Sherbrooke Molecular Imaging Center, Étienne-Le Bel Clinical Research Center of CHUS, Université de Sherbrooke, Québec, Canada.

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http://dx.doi.org/10.1097/MNM.0000000000000097DOI Listing
June 2014

The relative contribution of cognition and symptomatic remission to functional outcome following treatment of a first episode of psychosis.

J Clin Psychiatry 2014 Jun;75(6):e566-72

Prevention and Early Intervention Program for Psychoses (PEPP-Montreal), Douglas Mental Health University Institute, 6875 Blvd Lasalle, Montreal, Quebec H4H 1R3, Canada

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http://dx.doi.org/10.4088/JCP.13m08606DOI Listing
June 2014

Impact of drug size on brain tumor and brain parenchyma delivery after a blood-brain barrier disruption.

J Cereb Blood Flow Metab 2014 May 12;34(5):820-6. Epub 2014 Feb 12.

Département de chirurgie, service de neurochirurgie et de neuro-oncologie, Université de Sherbrooke, Sherbrooke, Quebec, Canada.

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http://dx.doi.org/10.1038/jcbfm.2014.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013755PMC
May 2014

Neural correlates of recognition memory of social information in people with schizophrenia.

J Psychiatry Neurosci 2014 Mar;39(2):97-109

Department of Psychiatry, McGill University, Montréal, Que. Douglas Mental Health University Institute, Montréal, Que., Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937286PMC
March 2014

Do motivation deficits in schizophrenia-spectrum disorders promote cannabis use? An investigation of behavioural response to natural rewards and drug cues.

Psychiatry Res 2014 Mar 21;215(3):522-7. Epub 2013 Dec 21.

McGill University, Douglas Mental Health University Institute, 6875 Boul., Lasalle, Montreal, Qc, Canada H4H 1R3. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2013.12.021DOI Listing
March 2014

Changes in memory performance over a 12-month period in relation to achieving symptomatic remission after a first-episode psychosis.

Schizophr Res 2014 Mar 7;153(1-3):103-8. Epub 2014 Feb 7.

Prevention Early Intervention Program for Psychoses (PEPP-Montreal), Douglas Mental Health University Institute, 6875 LaSalle Blvd., Montréal, Québec H4H 1R3, Canada; Université du Québec À Montréal, Psychology Department, 320 Sainte-Catherine Street East, Montréal, Québec H3C 3P8, Canada; McGill University, Department of Psychology, 1205 Dr. Penfield Avenue, Montréal, Québec H3A 1B1, Canada; McGill University, Department of Psychiatry, 1033 Pine Avenue West, Montréal, Québec H3A 1A1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2014.01.024DOI Listing
March 2014

TCF4 gene polymorphism and cognitive performance in patients with first episode psychosis.

Schizophr Res 2014 Jan 22;152(1):124-9. Epub 2013 Nov 22.

Douglas Mental Health University Institute, Canada; Department of Human Genetics, McGill University, Canada; Department of Psychiatry, McGill University, Canada; Integrated Program in Neuroscience, McGill University, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2013.10.038DOI Listing
January 2014

Predictors of cognition in first episode psychosis.

Schizophr Res 2014 Jan 25;152(1):164-9. Epub 2013 Nov 25.

Department of Psychiatry, McGill University, Montreal, Quebec, Canada; Prevention and Early Intervention Program for the Psychoses, Douglas Mental Health University Institute, Montreal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2013.10.044DOI Listing
January 2014

Neurocognition: clinical and functional outcomes in schizophrenia.

Can J Psychiatry 2014 Jan;59(1):5-12

Associate Professor, Department of Psychology, Queen's University, Kingston, Ontario.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079224PMC
http://dx.doi.org/10.1177/070674371405900103DOI Listing
January 2014

Dual kinin B1 and B2 receptor activation provides enhanced blood-brain barrier permeability and anticancer drug delivery into brain tumors.

Cancer Biol Ther 2013 Sep 14;14(9):806-11. Epub 2013 Jun 14.

Department of Pharmacology; Faculty of Medicine and Health Sciences; Université de Sherbrooke; Sherbrooke, Canada; Institute of Pharmacology (IPS); Faculty of Medicine and Health Sciences; Université de Sherbrooke; Sherbrooke, Canada.

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http://dx.doi.org/10.4161/cbt.25327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909549PMC
September 2013

Involvement of neuronal IL-1β in acquired brain lesions in a rat model of neonatal encephalopathy.

J Neuroinflammation 2013 Sep 5;10:110. Epub 2013 Sep 5.

Laboratoire de Neurologie Pédiatrique, Université de Sherbrooke, 3001 12e Avenue Nord, J1H 5N4 Sherbrooke, Québec, Canada.

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http://dx.doi.org/10.1186/1742-2094-10-110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844447PMC
September 2013

Persistent negative symptoms in schizophrenia: survey of Canadian psychiatrists.

Int Psychiatry 2013 Aug 1;10(3):69-72. Epub 2013 Aug 1.

Professor, Department of Psychiatry, McGill University, Montreal, Quebec; Director, Prevention and Early Intervention Program for the Psychoses, Douglas Mental Health University Institute, Montreal, Quebec, Canada, email

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735122PMC
August 2013

Impairment in verbal memory observed in first episode psychosis patients with persistent negative symptoms.

Schizophr Res 2013 Jul 28;147(2-3):223-9. Epub 2013 Apr 28.

Prevention and Early Intervention Program for Psychoses, Douglas Mental Health University Institute, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.schres.2013.04.006DOI Listing
July 2013

Mammary cancer bone metastasis follow-up using multimodal small-animal MR and PET imaging.

J Nucl Med 2013 Jun 17;54(6):944-52. Epub 2013 Apr 17.

Département de physiologie et biophysique, Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Sherbrooke, Quebec, Canada.

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June 2013

Repetitive transcranial magnetic stimulation (rTMS) for treating major depression and schizophrenia: a systematic review of recent meta-analyses.

Ann Med 2013 Jun 20;45(4):308-21. Epub 2013 May 20.

Neuromodulation Program, Douglas Mental Health University Institute and McGill University, Montréal, Québec, Canada.

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http://dx.doi.org/10.3109/07853890.2013.783993DOI Listing
June 2013

A diffusion-compensated model for the analysis of DCE-MRI data: theory, simulations and experimental results.

Phys Med Biol 2013 Mar 4;58(6):1983-98. Epub 2013 Mar 4.

Department of Radiology, Northwestern University Chicago, IL 60611, USA.

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http://dx.doi.org/10.1088/0031-9155/58/6/1983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646091PMC
March 2013