Martin Kennedy

Martin Kennedy

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A multiplex pharmacogenetics assay using the MinION nanopore sequencing device.

Pharmacogenet Genomics 2019 Nov;29(9):207-215

Department of Pathology and Biomedical Science, University of Otago, Christchurch.

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http://dx.doi.org/10.1097/FPC.0000000000000385DOI Listing
November 2019

PharmVar GeneReview: CYP2D6.

Clin Pharmacol Ther 2019 Sep 22. Epub 2019 Sep 22.

Division of Clinical Pharmacology, Toxicology & Therapeutic Innovation, Children's Mercy Kansas City, Kansas City and School of Medicine, University of Missouri-Kansas City, Kansas City, MO, USA.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/cpt.1643
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http://dx.doi.org/10.1002/cpt.1643DOI Listing
September 2019

Nanopore sequencing of the pharmacogene allows simultaneous haplotyping and detection of duplications.

Pharmacogenomics 2019 Sep;20(14):1033-1047

Department of Pathology & Biomedical Science, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.2217/pgs-2019-0080DOI Listing
September 2019

The Three Ps: Psychiatry, Pharmacy, and Pharmacogenomics, a Brief Report From New Zealand.

Front Psychiatry 2019 20;10:690. Epub 2019 Sep 20.

Gene Structure and Function Lab, Carney Centre for Pharmacogenomics, Department of Pathology & Biomedical Science, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.3389/fpsyt.2019.00690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6764017PMC
September 2019

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.

Authors:
Hunna J Watson Zeynep Yilmaz Laura M Thornton Christopher Hübel Jonathan R I Coleman Héléna A Gaspar Julien Bryois Anke Hinney Virpi M Leppä Manuel Mattheisen Sarah E Medland Stephan Ripke Shuyang Yao Paola Giusti-Rodríguez Ken B Hanscombe Kirstin L Purves Roger A H Adan Lars Alfredsson Tetsuya Ando Ole A Andreassen Jessica H Baker Wade H Berrettini Ilka Boehm Claudette Boni Vesna Boraska Perica Katharina Buehren Roland Burghardt Matteo Cassina Sven Cichon Maurizio Clementi Roger D Cone Philippe Courtet Scott Crow James J Crowley Unna N Danner Oliver S P Davis Martina de Zwaan George Dedoussis Daniela Degortes Janiece E DeSocio Danielle M Dick Dimitris Dikeos Christian Dina Monika Dmitrzak-Weglarz Elisa Docampo Laramie E Duncan Karin Egberts Stefan Ehrlich Geòrgia Escaramís Tõnu Esko Xavier Estivill Anne Farmer Angela Favaro Fernando Fernández-Aranda Manfred M Fichter Krista Fischer Manuel Föcker Lenka Foretova Andreas J Forstner Monica Forzan Christopher S Franklin Steven Gallinger Ina Giegling Johanna Giuranna Fragiskos Gonidakis Philip Gorwood Monica Gratacos Mayora Sébastien Guillaume Yiran Guo Hakon Hakonarson Konstantinos Hatzikotoulas Joanna Hauser Johannes Hebebrand Sietske G Helder Stefan Herms Beate Herpertz-Dahlmann Wolfgang Herzog Laura M Huckins James I Hudson Hartmut Imgart Hidetoshi Inoko Vladimir Janout Susana Jiménez-Murcia Antonio Julià Gursharan Kalsi Deborah Kaminská Jaakko Kaprio Leila Karhunen Andreas Karwautz Martien J H Kas James L Kennedy Anna Keski-Rahkonen Kirsty Kiezebrink Youl-Ri Kim Lars Klareskog Kelly L Klump Gun Peggy S Knudsen Maria C La Via Stephanie Le Hellard Robert D Levitan Dong Li Lisa Lilenfeld Bochao Danae Lin Jolanta Lissowska Jurjen Luykx Pierre J Magistretti Mario Maj Katrin Mannik Sara Marsal Christian R Marshall Morten Mattingsdal Sara McDevitt Peter McGuffin Andres Metspalu Ingrid Meulenbelt Nadia Micali Karen Mitchell Alessio Maria Monteleone Palmiero Monteleone Melissa A Munn-Chernoff Benedetta Nacmias Marie Navratilova Ioanna Ntalla Julie K O'Toole Roel A Ophoff Leonid Padyukov Aarno Palotie Jacques Pantel Hana Papezova Dalila Pinto Raquel Rabionet Anu Raevuori Nicolas Ramoz Ted Reichborn-Kjennerud Valdo Ricca Samuli Ripatti Franziska Ritschel Marion Roberts Alessandro Rotondo Dan Rujescu Filip Rybakowski Paolo Santonastaso André Scherag Stephen W Scherer Ulrike Schmidt Nicholas J Schork Alexandra Schosser Jochen Seitz Lenka Slachtova P Eline Slagboom Margarita C T Slof-Op 't Landt Agnieszka Slopien Sandro Sorbi Beata Świątkowska Jin P Szatkiewicz Ioanna Tachmazidou Elena Tenconi Alfonso Tortorella Federica Tozzi Janet Treasure Artemis Tsitsika Marta Tyszkiewicz-Nwafor Konstantinos Tziouvas Annemarie A van Elburg Eric F van Furth Gudrun Wagner Esther Walton Elisabeth Widen Eleftheria Zeggini Stephanie Zerwas Stephan Zipfel Andrew W Bergen Joseph M Boden Harry Brandt Steven Crawford Katherine A Halmi L John Horwood Craig Johnson Allan S Kaplan Walter H Kaye James E Mitchell Catherine M Olsen John F Pearson Nancy L Pedersen Michael Strober Thomas Werge David C Whiteman D Blake Woodside Garret D Stuber Scott Gordon Jakob Grove Anjali K Henders Anders Juréus Katherine M Kirk Janne T Larsen Richard Parker Liselotte Petersen Jennifer Jordan Martin Kennedy Grant W Montgomery Tracey D Wade Andreas Birgegård Paul Lichtenstein Claes Norring Mikael Landén Nicholas G Martin Preben Bo Mortensen Patrick F Sullivan Gerome Breen Cynthia M Bulik

Nat Genet 2019 Aug 15;51(8):1207-1214. Epub 2019 Jul 15.

Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1038/s41588-019-0439-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779477PMC
August 2019

Weathering in a world without terrestrial life recorded in the Mesoproterozoic Velkerri Formation.

Nat Commun 2019 08 1;10(1):3448. Epub 2019 Aug 1.

Department of Earth and Planetary Sciences, Macquarie University, Sydney, 2109, Australia.

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http://dx.doi.org/10.1038/s41467-019-11421-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6671950PMC
August 2019

Metoclopramide-Induced Acute Dystonic Reactions May Be Associated With the CYP2D6 Poor Metabolizer Status and Pregnancy-Related Hormonal Changes.

Front Pharmacol 2019 22;10:931. Epub 2019 Aug 22.

Carney Centre for Pharmacogenomics and Department of Pathology and Biomedical Science, University of Otago, Christchurch, Christchurch, New Zealand.

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http://dx.doi.org/10.3389/fphar.2019.00931DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713716PMC
August 2019

Associations between schizophrenia genetic risk, anxiety disorders and manic/hypomanic episode in a longitudinal population cohort study.

Br J Psychiatry 2019 02 26;214(2):96-102. Epub 2018 Nov 26.

Professor,Division of Psychological Medicine and Clinical Neurosciences,Cardiff University and School of Psychology, University of Sussex and School of Psychology,Trinity College,UK.

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https://www.cambridge.org/core/product/identifier/S000712501
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http://dx.doi.org/10.1192/bjp.2018.227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429243PMC
February 2019

Pharmacogenetics of angiotensin-converting enzyme inhibitor-induced angioedema.

Clin Exp Allergy 2019 02 8;49(2):142-154. Epub 2019 Jan 8.

Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1111/cea.13326DOI Listing
February 2019

Gene expression effects of lithium and valproic acid in a serotonergic cell line.

Physiol Genomics 2019 02 21;51(2):43-50. Epub 2018 Dec 21.

Carney Centre for Pharmacogenomics, Department of Pathology and Biomedical Science, University of Otago , Christchurch , New Zealand.

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http://dx.doi.org/10.1152/physiolgenomics.00069.2018DOI Listing
February 2019

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.

Authors:
Raymond K Walters Renato Polimanti Emma C Johnson Jeanette N McClintick Mark J Adams Amy E Adkins Fazil Aliev Silviu-Alin Bacanu Anthony Batzler Sarah Bertelsen Joanna M Biernacka Tim B Bigdeli Li-Shiun Chen Toni-Kim Clarke Yi-Ling Chou Franziska Degenhardt Anna R Docherty Alexis C Edwards Pierre Fontanillas Jerome C Foo Louis Fox Josef Frank Ina Giegling Scott Gordon Laura M Hack Annette M Hartmann Sarah M Hartz Stefanie Heilmann-Heimbach Stefan Herms Colin Hodgkinson Per Hoffmann Jouke Jan Hottenga Martin A Kennedy Mervi Alanne-Kinnunen Bettina Konte Jari Lahti Marius Lahti-Pulkkinen Dongbing Lai Lannie Ligthart Anu Loukola Brion S Maher Hamdi Mbarek Andrew M McIntosh Matthew B McQueen Jacquelyn L Meyers Yuri Milaneschi Teemu Palviainen John F Pearson Roseann E Peterson Samuli Ripatti Euijung Ryu Nancy L Saccone Jessica E Salvatore Sandra Sanchez-Roige Melanie Schwandt Richard Sherva Fabian Streit Jana Strohmaier Nathaniel Thomas Jen-Chyong Wang Bradley T Webb Robbee Wedow Leah Wetherill Amanda G Wills Jason D Boardman Danfeng Chen Doo-Sup Choi William E Copeland Robert C Culverhouse Norbert Dahmen Louisa Degenhardt Benjamin W Domingue Sarah L Elson Mark A Frye Wolfgang Gäbel Caroline Hayward Marcus Ising Margaret Keyes Falk Kiefer John Kramer Samuel Kuperman Susanne Lucae Michael T Lynskey Wolfgang Maier Karl Mann Satu Männistö Bertram Müller-Myhsok Alison D Murray John I Nurnberger Aarno Palotie Ulrich Preuss Katri Räikkönen Maureen D Reynolds Monika Ridinger Norbert Scherbaum Marc A Schuckit Michael Soyka Jens Treutlein Stephanie Witt Norbert Wodarz Peter Zill Daniel E Adkins Joseph M Boden Dorret I Boomsma Laura J Bierut Sandra A Brown Kathleen K Bucholz Sven Cichon E Jane Costello Harriet de Wit Nancy Diazgranados Danielle M Dick Johan G Eriksson Lindsay A Farrer Tatiana M Foroud Nathan A Gillespie Alison M Goate David Goldman Richard A Grucza Dana B Hancock Kathleen Mullan Harris Andrew C Heath Victor Hesselbrock John K Hewitt Christian J Hopfer John Horwood William Iacono Eric O Johnson Jaakko A Kaprio Victor M Karpyak Kenneth S Kendler Henry R Kranzler Kenneth Krauter Paul Lichtenstein Penelope A Lind Matt McGue James MacKillop Pamela A F Madden Hermine H Maes Patrik Magnusson Nicholas G Martin Sarah E Medland Grant W Montgomery Elliot C Nelson Markus M Nöthen Abraham A Palmer Nancy L Pedersen Brenda W J H Penninx Bernice Porjesz John P Rice Marcella Rietschel Brien P Riley Richard Rose Dan Rujescu Pei-Hong Shen Judy Silberg Michael C Stallings Ralph E Tarter Michael M Vanyukov Scott Vrieze Tamara L Wall John B Whitfield Hongyu Zhao Benjamin M Neale Joel Gelernter Howard J Edenberg Arpana Agrawal

Nat Neurosci 2018 12 26;21(12):1656-1669. Epub 2018 Nov 26.

Washington University School of Medicine, Department of Psychiatry, St. Louis, MO, USA.

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http://dx.doi.org/10.1038/s41593-018-0275-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430207PMC
December 2018

Epigenetics, nutrition and mental health. Is there a relationship?

Nutr Neurosci 2018 Nov 29;21(9):602-613. Epub 2017 May 29.

a Department of Pathology , University of Otago , P.O. Box 4345, Christchurch , New Zealand.

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https://www.tandfonline.com/doi/full/10.1080/1028415X.2017.1
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http://dx.doi.org/10.1080/1028415X.2017.1331524DOI Listing
November 2018

Methylomic changes in response to micronutrient supplementation and MTHFR genotype.

Epigenomics 2018 09 5;10(9):1201-1214. Epub 2018 Sep 5.

Department of Pathology and Biomedical Science, University of Otago, Christchurch, P.O. Box 4345, Christchurch, New Zealand.

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http://dx.doi.org/10.2217/epi-2018-0029DOI Listing
September 2018

Testicular Cancer in New Zealand (TCNZ) study: protocol for a national case-control study.

BMJ Open 2018 08 5;8(8):e025212. Epub 2018 Aug 5.

Cancer and Chronic Conditions (C3) Research Group, Department of Public Health, University of Otago, Wellington, New Zealand.

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http://dx.doi.org/10.1136/bmjopen-2018-025212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078234PMC
August 2018

A genome project for Māori and Pasifika: charting a path to equity in genomic medicine for Aotearoa.

Authors:
Martin A Kennedy

N Z Med J 2018 08 17;131(1480):8-10. Epub 2018 Aug 17.

PhD, Research Professor and Head of Department, Pathology and Biomedical Science, University of Otago, Christchurch.

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August 2018

Multiplexed Nanopore Sequencing of HLA-B Locus in Māori and Pacific Island Samples.

Front Genet 2018 30;9:152. Epub 2018 Apr 30.

Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.3389/fgene.2018.00152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936980PMC
April 2018

Long Fragment Polymerase Chain Reaction.

Methods Mol Biol 2017 ;1620:65-74

Department of Pathology and Carney Centre for Pharmacogenomics, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1007/978-1-4939-7060-5_3DOI Listing
February 2018

Complete Genome Sequence of Isolated from a Patient with Legionnaires' Disease.

Genome Announc 2018 Feb 1;6(5). Epub 2018 Feb 1.

Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1128/genomeA.01588-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794962PMC
February 2018

A New Zealand platform to enable genetic investigation of adverse drug reactions.

N Z Med J 2017 Dec 1;130(1466):62-69. Epub 2017 Dec 1.

Department of Pathology, University of Otago, Christchurch.

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December 2017

Structural Analysis of G-Quadruplex Formation at the Human MEST Promoter.

PLoS One 2017 4;12(1):e0169433. Epub 2017 Jan 4.

Department of Pathology, School of Medicine, University of Otago, Christchurch, New Zealand.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0169433PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214457PMC
August 2017

Methylated Cytosine Maintains G-Quadruplex Structures during Polymerase Chain Reaction and Contributes to Allelic Dropout.

Biochemistry 2017 07 10;56(29):3691-3698. Epub 2017 Jul 10.

Department of Pathology, University of Otago , Christchurch, New Zealand.

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http://dx.doi.org/10.1021/acs.biochem.7b00480DOI Listing
July 2017

Effect of 7,8-dihydroneopterin mediated CD36 down regulation and oxidant scavenging on oxidised low-density lipoprotein induced cell death in human macrophages.

Int J Biochem Cell Biol 2017 06 27;87:27-33. Epub 2017 Mar 27.

Free Radical Biochemistry Laboratory, School of Biological Sciences, University of Canterbury, Private Bag 4800, Christchurch, New Zealand; Department of Radiology, University of Otago, Christchurch, New Zealand. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2017.03.017DOI Listing
June 2017

Polymorphisms in CYP2C8 and CYP3A5 genes in the Nigerian population.

Drug Metab Pharmacokinet 2017 Jun 14;32(3):189-191. Epub 2016 Sep 14.

Department of Pathology & Carney Centre for Pharmacogenomics, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1016/j.dmpk.2016.09.001DOI Listing
June 2017

Allelic Dropout During Polymerase Chain Reaction due to G-Quadruplex Structures and DNA Methylation Is Widespread at Imprinted Human Loci.

G3 (Bethesda) 2017 03 10;7(3):1019-1025. Epub 2017 Mar 10.

Department of Pathology, University of Otago, Christchurch 8140, New Zealand

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http://dx.doi.org/10.1534/g3.116.038687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345703PMC
March 2017

Microsatellite polymorphisms associated with human behavioural and psychological phenotypes including a gene-environment interaction.

BMC Med Genet 2017 Feb 3;18(1):12. Epub 2017 Feb 3.

Department of Pathology, University of Otago, Christchurch, PO Box 4345, Christchurch, New Zealand.

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http://dx.doi.org/10.1186/s12881-017-0374-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291968PMC
February 2017

Mean telomere length is not associated with current health status in a 50-year-old population sample.

Am J Hum Biol 2017 Jan 26;29(1). Epub 2016 Aug 26.

Gene Structure and Function Laboratory, Department of Pathology, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1002/ajhb.22906DOI Listing
January 2017

[Letter to the Editor] Many commercial hot-start polymerases demonstrate activity prior to thermal activation.

Biotechniques 2016 12 1;61(6):293-296. Epub 2016 Dec 1.

Gene Structure and Function Laboratory, Department of Pathology, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.2144/000114481DOI Listing
December 2016

Genetic Evidence of a Population Bottleneck and Inbreeding in the Endangered New Zealand Sea Lion, Phocarctos hookeri.

J Hered 2016 09 19;107(5):392-402. Epub 2016 Mar 19.

From the Department of Anatomy, University of Otago, 270 Great King Street, Dunedin 9016, New Zealand (Osborne and Gemmell); Department of Pathology, University of Otago, Christchurch, New Zealand (Osborne and Kennedy); Computational Biology Group, Swiss Institute of Bioinformatics, Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland (Negro); Marine Species and Threats Team, Department of Conservation, Wellington, New Zealand (Chilvers); Department of Zoology, University of Otago, Dunedin, New Zealand (Robertson); and Allan Wilson Centre for Molecular Ecology and Evolution, University of Otago, Dunedin, New Zealand (Gemmell). B. Louise Chilvers is now at Wildbase, Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North 4442, New Zealand.

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http://dx.doi.org/10.1093/jhered/esw015DOI Listing
September 2016

DNA G-quadruplexes show strong interaction with DNA methyltransferases in vitro.

FEBS Lett 2016 09 11;590(17):2870-83. Epub 2016 Aug 11.

Department of Pathology, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1002/1873-3468.12331DOI Listing
September 2016

Agreement Between Doppler and Invasive Blood Pressure Monitoring in Anesthetized Dogs Weighing <5 kg.

J Am Anim Hosp Assoc 2015 Sep-Oct;51(5):300-5

From the Department of Anesthesia and Pain Management, University of Wisconsin Veterinary Medical Teaching Hospital, Madison, WI (M.K.); and Anesthesia Section, University of Minnesota, Veterinary Medical Center, Saint Paul, MN (M.B.).

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http://dx.doi.org/10.5326/JAAHA-MS-6163DOI Listing
August 2016

Fluorescence Methods for Probing G-Quadruplex Structure in Single- and Double-Stranded DNA.

Biochemistry 2016 07 16;55(26):3714-25. Epub 2016 Jun 16.

Department of Pathology, University of Otago , Christchurch, New Zealand.

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http://dx.doi.org/10.1021/acs.biochem.6b00327DOI Listing
July 2016

Personalised prescribing in psychiatry: Has pharmacogenomics delivered on its promise?

Aust N Z J Psychiatry 2016 Jun 24;50(6):509-10. Epub 2016 Mar 24.

Department of Pathology, University of Otago - Christchurch, Christchurch, New Zealand.

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http://dx.doi.org/10.1177/0004867416640099DOI Listing
June 2016

Examining the role of components of Slc11a1 (Nramp1) in the susceptibility of New Zealand sea lions (Phocarctos hookeri) to disease.

PLoS One 2015 14;10(4):e0122703. Epub 2015 Apr 14.

Department of Anatomy, University of Otago, Dunedin, New Zealand; Allan Wilson Centre for Molecular Ecology and Evolution, University of Otago, Dunedin, New Zealand.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122703PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397024PMC
April 2016

Impact of New Genomic Technologies on Understanding Adverse Drug Reactions.

Clin Pharmacokinet 2016 Apr;55(4):419-36

Department of Pathology and Carney Centre for Pharmacogenomics, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1007/s40262-015-0324-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791456PMC
April 2016

Erratum to: Impact of New Genomic Technologies on Understanding Adverse Drug Reactions.

Clin Pharmacokinet 2016 Apr;55(4):437

Department of Pathology and Carney Centre for Pharmacogenomics, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1007/s40262-016-0376-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969865PMC
April 2016

Cross-Comparison of Exome Analysis, Next-Generation Sequencing of Amplicons, and the iPLEX(®) ADME PGx Panel for Pharmacogenomic Profiling.

Front Pharmacol 2016 26;7. Epub 2016 Jan 26.

Carney Centre for Pharmacogenomics, Department of Pathology, University of Otago Christchurch, New Zealand.

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http://dx.doi.org/10.3389/fphar.2016.00001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726781PMC
February 2016

Valproic acid exposure leads to upregulation and increased promoter histone acetylation of sepiapterin reductase in a serotonergic cell line.

Neuropharmacology 2015 Dec 4;99:79-88. Epub 2015 Jul 4.

Gene Structure and Function Laboratory and Carney Centre for Pharmacogenomics, Department of Pathology, University of Otago, Christchurch, New Zealand. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2015.06.018DOI Listing
December 2015

A comparison of cardiopulmonary function, recovery quality, and total dosages required for induction and total intravenous anesthesia with propofol versus a propofol-ketamine combination in healthy Beagle dogs.

Vet Anaesth Analg 2015 Jul 21;42(4):350-9. Epub 2014 Jul 21.

Section of Anesthesia and Pain Management, Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI, USA.

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http://dx.doi.org/10.1111/vaa.12218DOI Listing
July 2015

No association between mean telomere length and life stress observed in a 30 year birth cohort.

PLoS One 2014 9;9(5):e97102. Epub 2014 May 9.

Gene Structure and Function Laboratory, Department of Pathology, University of Otago, Christchurch, New Zealand.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0097102PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016252PMC
June 2015

OPRM1 genotype and naltrexone response in depressed alcohol-dependent patients.

Pharmacogenet Genomics 2015 May;25(5):270-3

Departments of aPsychological Medicine bPathology, University of Otago Christchurch, Christchurch, New Zealand.

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http://dx.doi.org/10.1097/FPC.0000000000000128DOI Listing
May 2015

Choice of PCR microtube can impact on the success of long-range PCRs.

Anal Biochem 2015 May 9;477:115-7. Epub 2015 Mar 9.

Carney Centre for Pharmacogenomics and Department of Pathology, University of Otago, Christchurch, Christchurch, New Zealand. Electronic address:

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http://dx.doi.org/10.1016/j.ab.2015.02.023DOI Listing
May 2015

Heterozygote advantage at MHC DRB may influence response to infectious disease epizootics.

Mol Ecol 2015 Apr 19;24(7):1419-32. Epub 2015 Mar 19.

Department of Anatomy, University of Otago, PO Box 913, Dunedin, 9054, New Zealand; Department of Pathology, University of Otago, Christchurch, 8140, New Zealand.

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http://dx.doi.org/10.1111/mec.13128DOI Listing
April 2015

Telomere length measurement on the Roche LightCycler 480 Platform.

Genet Test Mol Biomarkers 2015 Feb 23;19(2):63-8. Epub 2014 Dec 23.

1 Gene Structure and Function Laboratory, Department of Pathology, University of Otago , Christchurch, Christchurch, New Zealand .

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http://www.liebertpub.com/doi/10.1089/gtmb.2014.0208
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http://dx.doi.org/10.1089/gtmb.2014.0208DOI Listing
February 2015

DUF1220 copy number is linearly associated with increased cognitive function as measured by total IQ and mathematical aptitude scores.

Hum Genet 2015 Jan 7;134(1):67-75. Epub 2014 Oct 7.

Department of Biochemistry and Molecular Genetics and Human Medical Genetics, Medical Scientist Training and Neuroscience Programs, University of Colorado School of Medicine, Anschutz Medical Campus, RC1-S, L18-10125, 12801 East 17th Ave, Mailstop 8101, P.O. Box 6511, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1007/s00439-014-1489-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898241PMC
January 2015

Stratification by smoking status reveals an association of CHRNA5-A3-B4 genotype with body mass index in never smokers.

PLoS Genet 2014 Dec 4;10(12):e1004799. Epub 2014 Dec 4.

BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, University of Glasgow, Glasgow, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1004799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256159PMC
December 2014

Anesthesia case of the month. Accidental lidocaine overdose during surgery for vertebral fractures.

J Am Vet Med Assoc 2014 Nov;245(10):1098-101

Section of Anesthesia and Pain Management, Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706.

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http://dx.doi.org/10.2460/javma.245.10.1098DOI Listing
November 2014

Broken heart syndrome -- is it a psychosomatic disorder?

J Psychosom Res 2014 Aug 20;77(2):158-60. Epub 2014 May 20.

Christchurch Heart Institute, Department of Medicine, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1016/j.jpsychores.2014.05.003DOI Listing
August 2014

Relevance of G-quadruplex structures to pharmacogenetics.

Front Pharmacol 2014 8;5:160. Epub 2014 Jul 8.

Department of Pathology, Carney Centre for Pharmacogenomics, University of Otago Christchurch, New Zealand.

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http://dx.doi.org/10.3389/fphar.2014.00160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085647PMC
July 2014

The presence of both serotonin 1A receptor (HTR1A) and dopamine transporter (DAT1) gene variants increase the risk of borderline personality disorder.

Front Genet 2014 Jan 7;4:313. Epub 2014 Jan 7.

Division of Pharmacy and Pharmaceutical Sciences, School of Applied Sciences, University of Huddersfield Huddersfield, UK.

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http://dx.doi.org/10.3389/fgene.2013.00313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882668PMC
January 2014

Perianesthetic complications in dogs undergoing magnetic resonance imaging of the brain for suspected intracranial disease.

J Am Vet Med Assoc 2013 Nov;243(9):1310-5

Department of Clinical Sciences, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 50118.

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http://dx.doi.org/10.2460/javma.243.9.1310DOI Listing
November 2013

Novel CYP2D6 and CYP2C19 variants identified in a patient with adverse reactions towards venlafaxine monotherapy and dual therapy with nortriptyline and fluoxetine.

Pharmacogenet Genomics 2013 Sep;23(9):494-7

Department of Pathology and Carney Centre for Pharmacogenomics, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1097/FPC.0b013e328363688dDOI Listing
September 2013

Progressing the utilisation of pharmacogenetics and pharmacogenomics into clinical care.

Pathology 2013 06;45(4):357-70

Department of Molecular and Clinical Genetics, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1097/PAT.0b013e328360b66eDOI Listing
June 2013

The nonlinear effects of evolutionary innovation biospheric feedbacks on qualitative environmental change: from the microbial to metazoan world.

Authors:
Martin Kennedy

Am Nat 2013 May 8;181 Suppl 1:S100-11. Epub 2013 Mar 8.

Sprigg Geobiology Centre, School of Earth and Environmental Sciences, University of Adelaide, Adelaide, SA 5005, Australia.

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http://dx.doi.org/10.1086/670023DOI Listing
May 2013

Institutional profile: The Carney Centre for Pharmacogenomics: a New Zealand focus for personalized medicine research.

Pharmacogenomics 2012 Jun;13(8):865-8

Carney Centre for Pharmacogenomics & Department of Pathology, University of Otago, Christchurch, PO Box 4345, Christchurch, New Zealand.

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http://dx.doi.org/10.2217/pgs.12.55DOI Listing
June 2012

Moderating role of the MAOA genotype in antisocial behaviour.

Br J Psychiatry 2012 Feb;200(2):116-23

Christchurch Health and Development Study, University of Otago, Christchurch, PO Box 4345, Christchurch, New Zealand.

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http://dx.doi.org/10.1192/bjp.bp.111.093328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269651PMC
February 2012

Clay mineral continental amplifier for marine carbon sequestration in a greenhouse ocean.

Proc Natl Acad Sci U S A 2011 Jun 16;108(24):9776-81. Epub 2011 May 16.

School of Earth and Environmental Science, University of Adelaide, Adelaide 5005, Australia. martin.kennedy@adelaide

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http://dx.doi.org/10.1073/pnas.1018670108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116409PMC
June 2011

MAOA, abuse exposure and antisocial behaviour: 30-year longitudinal study.

Br J Psychiatry 2011 Jun;198(6):457-63

Christchurch Health and Development Study, Department of Psychological Medicine, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1192/bjp.bp.110.086991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105117PMC
June 2011

Development of a predicted physical map of microsatellite locus positions for pinnipeds, with wider applicability to the Carnivora.

Mol Ecol Resour 2011 May 28;11(3):503-13. Epub 2010 Dec 28.

Department of Anatomy and Structural Biology, Centre for Reproduction and Genomics, University of Otago, Dunedin, New Zealand.

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http://dx.doi.org/10.1111/j.1755-0998.2010.02962.xDOI Listing
May 2011

Life stress, 5-HTTLPR and mental disorder: findings from a 30-year longitudinal study.

Br J Psychiatry 2011 Feb;198(2):129-35

Christchurch Health and Development Study, University of Otago, Christchurch, PO Box 4345, Christchurch, New Zealand.

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http://dx.doi.org/10.1192/bjp.bp.110.085993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031653PMC
February 2011

Clinical implications of pharmacogenetic variation on the effects of statins.

Drug Saf 2011 Jan;34(1):1-19

Department of Pharmacology and Toxicology, School of Medical Sciences, University of Otago, Dunedin, New Zealand.

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http://dx.doi.org/10.2165/11584380-000000000-00000DOI Listing
January 2011

Relationships between angry-impulsive personality traits and genetic polymorphisms of the dopamine transporter.

Biol Psychiatry 2009 Oct 15;66(8):717-21. Epub 2009 Apr 15.

Department of Psychological Medicine, University of Otago, Christchurch, Christchurch, New Zealand.

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http://dx.doi.org/10.1016/j.biopsych.2009.03.005DOI Listing
October 2009

Expression and association analyses of promoter variants of the neurogenic gene HES6, a candidate gene for mood disorder susceptibility and antidepressant response.

Neurosci Lett 2009 Aug 28;460(2):185-90. Epub 2009 May 28.

Gene Structure & Function Laboratory, Department of Pathology, University of Otago, Christchurch P.O. Box 4345, Christchurch, New Zealand.

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http://dx.doi.org/10.1016/j.neulet.2009.05.065DOI Listing
August 2009

The late Precambrian greening of the Earth.

Nature 2009 Aug 8;460(7256):728-32. Epub 2009 Jul 8.

School of Earth and Space Exploration, Arizona State University, Tempe, Arizona 85287-1404, USA.

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http://dx.doi.org/10.1038/nature08213DOI Listing
August 2009

Mineralogical constraints on the paleoenvironments of the Ediacaran Doushantuo Formation.

Proc Natl Acad Sci U S A 2009 Aug 29;106(32):13190-5. Epub 2009 Jul 29.

Department of Earth Sciences, University of California, Riverside, CA 92521, USA.

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http://dx.doi.org/10.1073/pnas.0901080106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726375PMC
August 2009

Polymorphisms of sepiapterin reductase gene alter promoter activity and may influence risk of bipolar disorder.

Pharmacogenet Genomics 2009 May;19(5):330-7

Department of Pathology, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1097/fpc.0b013e328328f82cDOI Listing
May 2009

Downregulation of Ccnd1 and Hes6 in rat hippocampus after chronic exposure to the antidepressant paroxetine.

Acta Neuropsychiatr 2008 Dec;20(6):307-13

1Department of Pathology, University of Otago, Christchurch, Christchurch, New Zealand.

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http://dx.doi.org/10.1111/j.1601-5215.2008.00334.xDOI Listing
December 2008

Tryptophan hydroxylase gene (TPH1) and peripheral tryptophan levels in depression.

J Affect Disord 2008 Jul 21;109(1-2):209-12. Epub 2008 Feb 21.

Department of Psychological Medicine, University of Otago, Christchurch, Christchurch, New Zealand.

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http://dx.doi.org/10.1016/j.jad.2007.11.010DOI Listing
July 2008

Incidence of Mycobacterium avium subspecies paratuberculosis in a population-based cohort of patients with Crohn's disease and control subjects.

Am J Gastroenterol 2008 May 26;103(5):1168-72. Epub 2008 Mar 26.

Department of Pathology, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1111/j.1572-0241.2007.01742.xDOI Listing
May 2008

Beyond TPMT: genetic influences on thiopurine drug responses in inflammatory bowel disease.

Per Med 2008 May;5(3):233-248

Department of Medicine, University of Otago, Christchurch 8140, New Zealand.

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http://dx.doi.org/10.2217/17410541.5.3.233DOI Listing
May 2008

Snowball Earth termination by destabilization of equatorial permafrost methane clathrate.

Nature 2008 May;453(7195):642-5

Department of Earth Science, University of California, Riverside, California 92521, USA.

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May 2008

Allele frequency differences of cytochrome P450 polymorphisms in a sample of New Zealand Māori.

N Z Med J 2008 Apr 18;121(1272):33-7. Epub 2008 Apr 18.

School of Biological Sciences, Victoria University of Wellington, New Zealand.

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April 2008

Role of epigenetics in mental disorders.

Aust N Z J Psychiatry 2008 Feb;42(2):97-107

Department of Pathology, University of Otago, Christchurch, New Zealand.

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http://journals.sagepub.com/doi/10.1080/00048670701787495
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http://dx.doi.org/10.1080/00048670701787495DOI Listing
February 2008

Ile164 variant of beta2-adrenoceptor does not influence outcome in heart failure but may interact with beta blocker treatment.

Eur J Heart Fail 2008 Jan;10(1):55-9

Department of Pathology and Carney Centre for Pharmacogenomics, University of Otago, Christchurch, PO Box 4345, Christchurch, New Zealand.

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http://dx.doi.org/10.1016/j.ejheart.2007.10.011DOI Listing
January 2008