Martin J Hessner

Martin J Hessner

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Martin J Hessner

Martin J Hessner

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Cystic Fibrosis Plasma Blunts the Immune Response to Bacterial Infection.

Am J Respir Cell Mol Biol 2019 Sep;61(3):301-311

Division of Pulmonary Medicine, Department of Pediatrics, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1165/rcmb.2018-0114OCDOI Listing
September 2019

Identification of a serum-induced transcriptional signature associated with metastatic cervical cancer.

PLoS One 2017 30;12(8):e0181242. Epub 2017 Aug 30.

Department of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0181242PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576712PMC
October 2017

Increased Expression of Plasma-Induced ABCC1 mRNA in Cystic Fibrosis.

Int J Mol Sci 2017 Aug 11;18(8). Epub 2017 Aug 11.

Division of Pulmonary Medicine, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, 225 E Chicago Ave., Chicago, IL 60611, USA.

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http://dx.doi.org/10.3390/ijms18081752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578142PMC
August 2017

Circulating Differentially Methylated Amylin DNA as a Biomarker of β-Cell Loss in Type 1 Diabetes.

PLoS One 2016 25;11(4):e0152662. Epub 2016 Apr 25.

Research Institute, Islet Biology, Winthrop-University Hospital, Mineola, NY, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0152662PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844136PMC
February 2017

TGF-β1 along with other platelet contents augments Treg cells to suppress anti-FVIII immune responses in hemophilia A mice.

Blood Adv 2016 Dec;1(2):139-151

Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI; Children's Research Institute, Children's Hospital of Wisconsin, Milwaukee, WI; Midwest Athletes Against Childhood Cancer Fund Research Center, Milwaukee, WI; Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI.

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http://www.bloodadvances.org/lookup/doi/10.1182/bloodadvance
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http://dx.doi.org/10.1182/bloodadvances.2016001453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288643PMC
December 2016

Interleukin-1 antagonism moderates the inflammatory state associated with Type 1 diabetes during clinical trials conducted at disease onset.

Eur J Immunol 2016 Apr 21;46(4):1030-46. Epub 2016 Jan 21.

The Max McGee National Research Center for Juvenile Diabetes, Children's Research Institute of Children's Hospital of Wisconsin, and Department of Pediatrics at the Medical College of Wisconsin, Milwaukee, WI, USA.

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http://dx.doi.org/10.1002/eji.201546005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828314PMC
April 2016

Blood-based signatures in type 1 diabetes.

Diabetologia 2016 Mar 23;59(3):414-25. Epub 2015 Dec 23.

The Max McGee National Research Center for Juvenile Diabetes, Children's Research Institute of Children's Hospital of Wisconsin, Milwaukee, WI, USA.

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http://dx.doi.org/10.1007/s00125-015-3843-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744128PMC
March 2016

Innate inflammation in type 1 diabetes.

Transl Res 2016 Jan 29;167(1):214-27. Epub 2015 Apr 29.

Max McGee National Research Center for Juvenile Diabetes, Children's Research Institute of Children's Hospital of Wisconsin, Milwaukee, Wis; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wis. Electronic address:

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http://dx.doi.org/10.1016/j.trsl.2015.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626442PMC
January 2016

Intermittent neonatal hypoxia elicits the upregulation of inflammatory-related genes in adult male rats through long-lasting programming effects.

Physiol Rep 2015 Dec;3(12)

Endocrine Research Laboratory, Aurora St. Luke's Medical Center Aurora Research Institute, Milwaukee, Wisconsin Departments of Medicine, Surgery, and Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin

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http://doi.wiley.com/10.14814/phy2.12646
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http://dx.doi.org/10.14814/phy2.12646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760434PMC
December 2015

Molecular signatures differentiate immune states in type 1 diabetic families.

Diabetes 2014 Nov 23;63(11):3960-73. Epub 2014 Apr 23.

The Max McGee National Research Center for Juvenile Diabetes, Children's Research Institute of Children's Hospital of Wisconsin, and Department of Pediatrics at the Medical College of Wisconsin, Milwaukee, WI

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http://dx.doi.org/10.2337/db14-0214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207392PMC
November 2014

Gene targeting in NOD mouse embryos using zinc-finger nucleases.

Diabetes 2014 Jan 23;63(1):68-74. Epub 2013 Aug 23.

Max McGee National Research Center for Juvenile Diabetes, Medical College of Wisconsin, Milwaukee, WI.

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http://dx.doi.org/10.2337/db13-0192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3868049PMC
January 2014

Mast cell activation and neutrophil recruitment promotes early and robust inflammation in the meninges in EAE.

J Autoimmun 2013 May 23;42:50-61. Epub 2012 Dec 23.

Northwestern University, Feinberg School of Medicine, Department of Microbiology and Immunology, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.jaut.2012.11.003DOI Listing
May 2013

Evaluation of Genomic Evidence for Oxidative Stress in Experimental Radiation Nephropathy.

J Genet Disord Genet Rep 2013 Jan;2(1)

Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.

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http://dx.doi.org/10.4172/2327-5790.1000101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013680PMC
January 2013

Requirements for growth and IL-10 expression of highly purified human T regulatory cells.

J Clin Immunol 2012 Oct 5;32(5):1118-28. Epub 2012 May 5.

Department of Pediatrics, Medical College of Wisconsin and the Children's Research Institute, Milwaukee, WI 53226, USA.

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http://dx.doi.org/10.1007/s10875-012-9701-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271826PMC
October 2012

Predicting disease-related subnetworks for type 1 diabetes using a new network activity score.

OMICS 2012 Oct 23;16(10):566-78. Epub 2012 Aug 23.

Department of Physics, the University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.

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http://dx.doi.org/10.1089/omi.2012.0029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459426PMC
October 2012

Use of transcriptional signatures induced in lymphoid and myeloid cell lines as an inflammatory biomarker in Type 1 diabetes.

Physiol Genomics 2011 Jun 15;43(11):697-709. Epub 2011 Mar 15.

Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics at the Medical College of Wisconsin, and The Children's Research Institute of Children's Hospital of Wisconsin, Milwaukee, Wisconsin 53226, USA.

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http://www.physiology.org/doi/10.1152/physiolgenomics.00235.
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http://dx.doi.org/10.1152/physiolgenomics.00235.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121160PMC
June 2011

Global analysis of phase locking in gene expression during cell cycle: the potential in network modeling.

BMC Syst Biol 2010 Dec 3;4:167. Epub 2010 Dec 3.

Department of Physics, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.

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http://dx.doi.org/10.1186/1752-0509-4-167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017040PMC
December 2010

Identification of a serum-induced transcriptional signature associated with type 1 diabetes in the BioBreeding rat.

Diabetes 2010 Oct 3;59(10):2375-85. Epub 2010 Aug 3.

Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics at the Medical College of Wisconsin, the Children's Research Institute of Children’s Hospital of Wisconsin, and theHuman and Molecular Genetics Center, Milwaukee, Wisconsin, USA.

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http://dx.doi.org/10.2337/db10-0372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279523PMC
October 2010

MB49 murine urothelial carcinoma: molecular and phenotypic comparison to human cell lines as a model of the direct tumor response to bacillus Calmette-Guerin.

J Urol 2009 Dec 23;182(6):2932-7. Epub 2009 Oct 23.

Department of Urology, Medical College of Wisconsin and Max McGee National Research Center for Juvenile Diabetes, Milwaukee, Wisconsin 53226, USA.

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http://dx.doi.org/10.1016/j.juro.2009.08.018DOI Listing
December 2009

An autoinflammatory disease due to homozygous deletion of the IL1RN locus.

N Engl J Med 2009 Jun;360(23):2438-44

Department of Pediatrics, Medical College of Wisconsin and the Children's Research Institute, Milwaukee 53201, USA.

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http://dx.doi.org/10.1056/NEJMoa0809568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803085PMC
June 2009

Identification of a molecular signature in human type 1 diabetes mellitus using serum and functional genomics.

J Immunol 2008 Feb;180(3):1929-37

Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics, Medical College of Wisconsin, Children's Hospital of Wisconsin, Milwaukee 53226, USA.

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http://dx.doi.org/10.4049/jimmunol.180.3.1929DOI Listing
February 2008

Quantitative measurement of pathogen-specific human memory T cell repertoire diversity using a CDR3 beta-specific microarray.

BMC Genomics 2007 Sep 19;8:329. Epub 2007 Sep 19.

The Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics, The Medical College of Wisconsin and The Children's Hospital Research Institute of Children's Hospital of Wisconsin, Milwaukee, WI 53226, USA.

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http://dx.doi.org/10.1186/1471-2164-8-329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2039751PMC
September 2007

Evidence of a functional role for mast cells in the development of type 1 diabetes mellitus in the BioBreeding rat.

J Immunol 2006 Nov;177(10):7275-86

Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics at the Medical College of Wisconsin, and Children's Research Institute of the Children's Hospital of Wisconsin, Milwaukee, WI 53226, USA.

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http://dx.doi.org/10.4049/jimmunol.177.10.7275DOI Listing
November 2006

The application of microarray analysis to pediatric diseases.

Pediatr Clin North Am 2006 Aug;53(4):579-90

The Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA.

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http://dx.doi.org/10.1016/j.pcl.2006.05.013DOI Listing
August 2006

Comprehensive quality control utilizing the prehybridization third-dye image leads to accurate gene expression measurements by cDNA microarrays.

BMC Bioinformatics 2006 Aug 14;7:378. Epub 2006 Aug 14.

The Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics, The Medical College of Wisconsin and Children's Hospital of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA.

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http://dx.doi.org/10.1186/1471-2105-7-378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1563483PMC
August 2006

Three-color cDNA microarrays with prehybridization quality control yield gene expression data comparable to that of commercial platforms.

Physiol Genomics 2006 Mar 10;25(1):166-78. Epub 2006 Jan 10.

The Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics, Medical College of Wisconsin, Children's Hospital Research Institute, Milwaukee, Wisconsin, USA.

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http://www.physiology.org/doi/10.1152/physiolgenomics.00243.
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http://dx.doi.org/10.1152/physiolgenomics.00243.2005DOI Listing
March 2006

Transcriptome analysis and kidney research: toward systems biology.

Kidney Int 2005 Jun;67(6):2114-22

Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA.

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http://dx.doi.org/10.1111/j.1523-1755.2005.00315.xDOI Listing
June 2005

Leucine culture reveals that ATP synthase functions as a fuel sensor in pancreatic beta-cells.

J Biol Chem 2004 Dec 14;279(52):53915-23. Epub 2004 Oct 14.

Department of Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1074/jbc.M405309200DOI Listing
December 2004

Involvement of eotaxin, eosinophils, and pancreatic predisposition in development of type 1 diabetes mellitus in the BioBreeding rat.

J Immunol 2004 Dec;173(11):6993-7002

The Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics at the Medical College of Wisconsin and the Children's Research Institute of the Children's Hospital of Wisconsin, Milwaukee, WI 53226, USA.

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http://dx.doi.org/10.4049/jimmunol.173.11.6993DOI Listing
December 2004

Immobilized probe and glass surface chemistry as variables in microarray fabrication.

BMC Genomics 2004 Aug 4;5(1):53. Epub 2004 Aug 4.

The Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics, The Medical College of Wisconsin and Children's Hospital of Wisconsin, Milwaukee, WI 53226, USA.

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http://dx.doi.org/10.1186/1471-2164-5-53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC512283PMC
August 2004

Effect of high glucose on gene expression in mesangial cells: upregulation of the thiol pathway is an adaptational response.

Physiol Genomics 2004 May 19;17(3):271-82. Epub 2004 May 19.

Department of Physiology, Milwaukee, Wisconsin 53226, USA.

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http://dx.doi.org/10.1152/physiolgenomics.00031.2004DOI Listing
May 2004

B.E.A.R. GeneInfo: a tool for identifying gene-related biomedical publications through user modifiable queries.

BMC Bioinformatics 2004 Apr 29;5:46. Epub 2004 Apr 29.

Department of Pathology and Bioinformatics Program, Medical College of Wisconsin, Milwaukee, WI, 53226, USA.

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http://dx.doi.org/10.1186/1471-2105-5-46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC419696PMC
April 2004

Utilization of a labeled tracking oligonucleotide for visualization and quality control of spotted 70-mer arrays.

BMC Genomics 2004 Feb 9;5(1):12. Epub 2004 Feb 9.

The Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics, The Medical College of Wisconsin and Children's Hospital of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA.

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http://dx.doi.org/10.1186/1471-2164-5-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC362869PMC
February 2004

A novel approach for high-quality microarray processing using third-dye array visualization technology.

IEEE Trans Nanobioscience 2003 Dec;2(4):193-201

Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI 53226, USA.

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http://ieeexplore.ieee.org/iel5/7728/28066/01254522.pdf
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December 2003

Difference in gene expression profiles between human CD4+CD25+ and CD4+CD25- T cells.

Ann N Y Acad Sci 2003 Nov;1005:279-83

Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics, Medical College and Children's Hospital of Wisconsin, Milwaukee, Wisconsin 53226, USA.

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http://dx.doi.org/10.1196/annals.1288.043DOI Listing
November 2003

The design of a gene chip for functional immunological studies on a high-quality control platform.

Ann N Y Acad Sci 2003 Nov;1005:284-7

Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics, Medical College and Children's Hospital of Wisconsin, Milwaukee, Wisconsin 53226, USA.

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http://dx.doi.org/10.1196/annals.1288.044DOI Listing
November 2003

Quantitative quality control in microarray experiments and the application in data filtering, normalization and false positive rate prediction.

Bioinformatics 2003 Jul;19(11):1341-7

Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics, Medical College and Children's Hospital of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA.

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http://dx.doi.org/10.1093/bioinformatics/btg154DOI Listing
July 2003

Use of a three-color cDNA microarray platform to measure and control support-bound probe for improved data quality and reproducibility.

Nucleic Acids Res 2003 Jun;31(11):e60

The Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics, The Medical College of Wisconsin and Children's Hospital of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC156737PMC
http://dx.doi.org/10.1093/nar/gng059DOI Listing
June 2003

Three color cDNA microarrays: quantitative assessment through the use of fluorescein-labeled probes.

Nucleic Acids Res 2003 Feb;31(4):e14

The Max McGee National Research Center for Juvenile Diabetes, The Medical College of Wisconsin and Children's Hospital of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC150246PMC
http://dx.doi.org/10.1093/nar/gng014DOI Listing
February 2003