Publications by authors named "Martin Hrabé de Angelis"

100Publications

Increased mitochondrial respiration of adipocytes from metabolically unhealthy obese compared to healthy obese individuals.

Sci Rep 2020 Jul 24;10(1):12407. Epub 2020 Jul 24.

Department of Internal Medicine IV, Division of Endocrinology, Diabetology, Nephrology, University Hospital Tübingen, Eberhard Karls University Tübingen, Otfried-Müller-Str. 10, 72076, Tübingen, Germany.

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http://dx.doi.org/10.1038/s41598-020-69016-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7382448PMC
July 2020

Introduction to Mammalian Genome Special Issue: Epigenetics.

Mamm Genome 2020 06;31(5-6):117-118

Institute of Experimental Genetics, Helmholtz Zentrum München GmbH, Neuherberg, Germany.

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http://dx.doi.org/10.1007/s00335-020-09843-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368862PMC
June 2020

Physiological relevance of the neuronal isoform of inositol-1,4,5-trisphosphate 3-kinases in mice.

Neurosci Lett 2020 Jun 25;735:135206. Epub 2020 Jun 25.

Department of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, D-20246, Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.neulet.2020.135206DOI Listing
June 2020

Biomedical Research Goes Viral: Dangers and Opportunities.

Cell 2020 06 11;181(6):1189-1193. Epub 2020 May 11.

Helmholtz Zentrum München, Neuherberg, Germany; Technische Universität München, München, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.05.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211590PMC
June 2020

Establishing sample-preparation protocols for X-ray phase-contrast CT of rodent spinal cords: Aldehyde fixations and osmium impregnation.

J Neurosci Methods 2020 Jun 27;339:108744. Epub 2020 Apr 27.

Department of Medical Physics, Faculty of Physics, Ludwig-Maximilians-Universität München, Garching, Germany; Department of Clinical Radiology, Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jneumeth.2020.108744DOI Listing
June 2020

Nutrition and its role in epigenetic inheritance of obesity and diabetes across generations.

Mamm Genome 2020 06 30;31(5-6):119-133. Epub 2020 Apr 30.

Institute of Experimental Genetics, Helmholtz Zentrum München GmbH, Neuherberg, Germany.

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http://dx.doi.org/10.1007/s00335-020-09839-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368866PMC
June 2020

Functional changes of the liver in the absence of growth hormone (GH) action - Proteomic and metabolomic insights from a GH receptor deficient pig model.

Mol Metab 2020 Jun 18;36:100978. Epub 2020 Mar 18.

Laboratory for Functional Genome Analysis, (LAFUGA), Gene Center, LMU Munich, 81377 Munich, Germany; Institute of Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, 81377 Munich, Germany; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2020.100978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7184181PMC
June 2020

iTAG-RNA Isolates Cell-Specific Transcriptional Responses to Environmental Stimuli and Identifies an RNA-Based Endocrine Axis.

Cell Rep 2020 Mar;30(9):3183-3194.e4

Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.02.020DOI Listing
March 2020

DLL1- and DLL4-Mediated Notch Signaling Is Essential for Adult Pancreatic Islet Homeostasis.

Diabetes 2020 May 6;69(5):915-926. Epub 2020 Feb 6.

Institute of Experimental Genetics and German Mouse Clinic, Helmholtz Zentrum München, Neuherberg, Germany

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http://dx.doi.org/10.2337/db19-0795DOI Listing
May 2020

Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice.

Nat Commun 2020 01 31;11(1):624. Epub 2020 Jan 31.

Institute for Diabetes and Obesity, Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), 85764, Neuherberg, Germany.

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http://dx.doi.org/10.1038/s41467-019-14069-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6994690PMC
January 2020

In-depth phenotyping reveals common and novel disease symptoms in a hemizygous knock-in mouse model (Mut-ko/ki) of mut-type methylmalonic aciduria.

Biochim Biophys Acta Mol Basis Dis 2020 03 23;1866(3):165622. Epub 2019 Nov 23.

Division of Metabolism and Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland; radiz - Rare Disease Initiative Zurich, Clinical Research Priority Program for Rare Diseases, University of Zurich, Zurich, Switzerland; Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2019.165622DOI Listing
March 2020

Spectral domain - Optical coherence tomography (SD-OCT) as a monitoring tool for alterations in mouse lenses.

Exp Eye Res 2020 01 18;190:107871. Epub 2019 Nov 18.

Helmholtz Zentrum München GmbH - German Research Center for Environmental Health, Institute of Experimental Genetics, Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.exer.2019.107871DOI Listing
January 2020

CRN2 binds to TIMP4 and MMP14 and promotes perivascular invasion of glioblastoma cells.

Eur J Cell Biol 2019 Dec 11;98(5-8):151046. Epub 2019 Oct 11.

Centre for Biochemistry, Institute of Biochemistry I, Medical Faculty, University of Cologne, 50931, Cologne, Germany; Institute of Neuropathology, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nürnberg, 91054, Erlangen, Germany; Center for Physiology and Pathophysiology, Institute of Vegetative Physiology, Medical Faculty, University of Cologne, 50931, Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejcb.2019.151046DOI Listing
December 2019

Costs of Implementing Quality in Research Practice.

Handb Exp Pharmacol 2020 ;257:399-423

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.

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http://dx.doi.org/10.1007/164_2019_294DOI Listing
March 2020

AMPK Subunits Harbor Largely Nonoverlapping Genetic Determinants for Body Fat Mass, Glucose Metabolism, and Cholesterol Metabolism.

J Clin Endocrinol Metab 2020 01;105(1)

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Centre Munich at the University of Tübingen, 72076 Tübingen, Germany.

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http://dx.doi.org/10.1210/clinem/dgz020DOI Listing
January 2020

Multi-omics insights into functional alterations of the liver in insulin-deficient diabetes mellitus.

Mol Metab 2019 08 4;26:30-44. Epub 2019 Jun 4.

Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, 81377 Munich, Germany; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany; Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, 81377 Munich, Germany; Center for Innovative Medical Models (CiMM), LMU Munich, 85764 Oberschleißheim, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2019.05.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667734PMC
August 2019

Genes Whose Gain or Loss-of-Function Increases Endurance Performance in Mice: A Systematic Literature Review.

Front Physiol 2019 22;10:262. Epub 2019 Mar 22.

Exercise Biology Group, Department of Sport and Health Sciences, Technical University of Munich, Munich, Germany.

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http://dx.doi.org/10.3389/fphys.2019.00262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439621PMC
March 2019

Erratum: Author Correction: Identification of genes required for eye development by high-throughput screening of mouse knockouts.

Commun Biol 2019 7;2:97. Epub 2019 Mar 7.

Department of Ophthalmology & Vision Science, School of Medicine, U.C. Davis, Sacramento, CA, 95817, USA.

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http://dx.doi.org/10.1038/s42003-019-0349-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405960PMC
March 2019

Measuring and Interpreting Oxygen Consumption Rates in Whole Fly Head Segments.

J Vis Exp 2019 01 7(143). Epub 2019 Jan 7.

Laboratory for Metabolism and Epigenetics in Aging, Leibniz Institute for Farm Animal Biology (FBN); Laboratory for Metabolism and Epigenetics in Brain Aging, Institute of Neuroregeneration & Neurorehabilitation of Qingdao University; Molecular Biology Division, Biomedical Center, Faculty of Medicine, Ludwig-Maximilians University of Munich;

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http://dx.doi.org/10.3791/58601DOI Listing
January 2019

Preadipocytes of obese humans display gender-specific bioenergetic responses to glucose and insulin.

Mol Metab 2019 02 26;20:28-37. Epub 2018 Nov 26.

Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany; Institute of Pharmaceutical Sciences, Department of Pharmacy and Biochemistry, Eberhard Karls University Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1016/j.molmet.2018.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358537PMC
February 2019

Impact of Brain Fatty Acid Signaling on Peripheral Insulin Action in Mice.

Exp Clin Endocrinol Diabetes 2020 Jan 5;128(1):20-29. Epub 2018 Nov 5.

German Center for Diabetes Research (DZD), Neuherberg, Germany.

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0735-9533
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http://dx.doi.org/10.1055/a-0735-9533DOI Listing
January 2020

Crybb2 Mutations Consistently Affect Schizophrenia Endophenotypes in Mice.

Mol Neurobiol 2019 Jun 6;56(6):4215-4230. Epub 2018 Oct 6.

Institute of Developmental Genetics, Helmholtz Zentrum München, German Research Centre for Environmental Health, 85764, Neuherberg, Germany.

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http://link.springer.com/10.1007/s12035-018-1365-5
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http://dx.doi.org/10.1007/s12035-018-1365-5DOI Listing
June 2019

Dilution correction for dynamically influenced urinary analyte data.

Anal Chim Acta 2018 Nov 28;1032:18-31. Epub 2018 Jul 28.

Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, Germany; Institute of Epidemiology, Helmholtz Zentrum München, Germany; German Center for Diabetes Research (DZD), München, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S00032670183093
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http://dx.doi.org/10.1016/j.aca.2018.07.068DOI Listing
November 2018

Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Göttingen minipigs.

Mol Metab 2018 10 28;16:180-190. Epub 2018 Jun 28.

Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, Feodor-Lynen-Str. 25, 81377, Munich, Germany; Center for Innovative Medical Models (CiMM), Department of Veterinary Sciences, LMU Munich, Hackerstr. 27, 85764, Oberschleißheim, Germany; German Center for Diabetes Research (DZD), Ingolstädter Landstr. 1, 85764, Neuherberg, Germany; Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, Feodor-Lynen-Str. 25, 81377, Munich, Germany.

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http://dx.doi.org/10.1016/j.molmet.2018.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157610PMC
October 2018

Micro-imaging of Brain Cancer Radiation Therapy Using Phase-contrast Computed Tomography.

Int J Radiat Oncol Biol Phys 2018 07 7;101(4):965-984. Epub 2018 Apr 7.

Department of Physics, Ludwig Maximilians University, Garching, Germany; Department of Clinical Radiology, Ludwig Maximilians University, Munich, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03603016183061
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http://dx.doi.org/10.1016/j.ijrobp.2018.03.063DOI Listing
July 2018

Genes Whose Gain or Loss-Of-Function Increases Skeletal Muscle Mass in Mice: A Systematic Literature Review.

Front Physiol 2018 22;9:553. Epub 2018 May 22.

Exercise Biology Group, Faculty of Sport and Health Sciences, Technical University of Munich, Munich, Germany.

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http://dx.doi.org/10.3389/fphys.2018.00553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992403PMC
May 2018

A Vitamin E-Enriched Antioxidant Diet Interferes with the Acute Adaptation of the Liver to Physical Exercise in Mice.

Nutrients 2018 Apr 28;10(5). Epub 2018 Apr 28.

Division of Pathobiochemistry and Clinical Chemistry, Department of Internal Medicine IV, University Hospital Tübingen, 72076 Tübingen, Germany.

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http://dx.doi.org/10.3390/nu10050547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986427PMC
April 2018

Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver.

Mol Metab 2018 05 15;11:113-128. Epub 2018 Mar 15.

Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, Feodor-Lynen-Str. 25, 81377 Munich, Germany; Center for Innovative Medical Models (CiMM), Department of Veterinary Sciences, LMU Munich, Hackerstr. 27, 85764 Oberschleißheim, Germany; Meiji University International Institute for Bio-Resource Research, 1-1-1 Higashimita, Tama, Kawasaki, 214-8571, Japan; German Center for Diabetes Research (DZD), Helmholtz Zentrum München, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany; Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, Feodor-Lynen-Str. 25, 81377 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2018.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001387PMC
May 2018

Prediction of Glucose Tolerance without an Oral Glucose Tolerance Test.

Front Endocrinol (Lausanne) 2018 19;9:82. Epub 2018 Mar 19.

Department of Internal Medicine IV, Division of Endocrinology, Diabetology, Nephrology, Vascular Disease and Clinical Chemistry, University Hospital of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.3389/fendo.2018.00082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868129PMC
March 2018

Pharmacogenetics of oral antidiabetic therapy.

Pharmacogenomics 2018 04 27;19(6):577-587. Epub 2018 Mar 27.

Institute for Diabetes Research & Metabolic Diseases of the Helmholtz Centre Munich at the Eberhard Karls University Tübingen, Germany.

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http://dx.doi.org/10.2217/pgs-2017-0195DOI Listing
April 2018

Rapid and transient oxygen consumption increase following acute HDAC/KDAC inhibition in Drosophila tissue.

Sci Rep 2018 03 8;8(1):4199. Epub 2018 Mar 8.

Munich Center of Integrated Protein Science and Biomedical Center, Ludwig-Maximilians University of Munich, Planegg-Martinsried, 80336, Germany.

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http://dx.doi.org/10.1038/s41598-018-22674-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5843646PMC
March 2018

Genome-wide analysis of PDX1 target genes in human pancreatic progenitors.

Mol Metab 2018 03 31;9:57-68. Epub 2018 Jan 31.

Institute of Diabetes and Regeneration Research, Helmholtz Zentrum München, Parkring 11, 85748, Garching, Germany; Institute of Stem Cell Research, Helmholtz Zentrum München, 85764 Neuherberg, Germany; Chair of ß-Cell Biology, Technische Universität München, Ismaningerstraße 22, 81675 München, Germany; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2018.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870105PMC
March 2018

Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.

Authors:
Jason Flannick Christian Fuchsberger Anubha Mahajan Tanya M Teslovich Vineeta Agarwala Kyle J Gaulton Lizz Caulkins Ryan Koesterer Clement Ma Loukas Moutsianas Davis J McCarthy Manuel A Rivas John R B Perry Xueling Sim Thomas W Blackwell Neil R Robertson N William Rayner Pablo Cingolani Adam E Locke Juan Fernandez Tajes Heather M Highland Josee Dupuis Peter S Chines Cecilia M Lindgren Christopher Hartl Anne U Jackson Han Chen Jeroen R Huyghe Martijn van de Bunt Richard D Pearson Ashish Kumar Martina Müller-Nurasyid Niels Grarup Heather M Stringham Eric R Gamazon Jaehoon Lee Yuhui Chen Robert A Scott Jennifer E Below Peng Chen Jinyan Huang Min Jin Go Michael L Stitzel Dorota Pasko Stephen C J Parker Tibor V Varga Todd Green Nicola L Beer Aaron G Day-Williams Teresa Ferreira Tasha Fingerlin Momoko Horikoshi Cheng Hu Iksoo Huh Mohammad Kamran Ikram Bong-Jo Kim Yongkang Kim Young Jin Kim Min-Seok Kwon Juyoung Lee Selyeong Lee Keng-Han Lin Taylor J Maxwell Yoshihiko Nagai Xu Wang Ryan P Welch Joon Yoon Weihua Zhang Nir Barzilai Benjamin F Voight Bok-Ghee Han Christopher P Jenkinson Teemu Kuulasmaa Johanna Kuusisto Alisa Manning Maggie C Y Ng Nicholette D Palmer Beverley Balkau Alena Stančáková Hanna E Abboud Heiner Boeing Vilmantas Giedraitis Dorairaj Prabhakaran Omri Gottesman James Scott Jason Carey Phoenix Kwan George Grant Joshua D Smith Benjamin M Neale Shaun Purcell Adam S Butterworth Joanna M M Howson Heung Man Lee Yingchang Lu Soo-Heon Kwak Wei Zhao John Danesh Vincent K L Lam Kyong Soo Park Danish Saleheen Wing Yee So Claudia H T Tam Uzma Afzal David Aguilar Rector Arya Tin Aung Edmund Chan Carmen Navarro Ching-Yu Cheng Domenico Palli Adolfo Correa Joanne E Curran Dennis Rybin Vidya S Farook Sharon P Fowler Barry I Freedman Michael Griswold Daniel Esten Hale Pamela J Hicks Chiea-Chuen Khor Satish Kumar Benjamin Lehne Dorothée Thuillier Wei Yen Lim Jianjun Liu Marie Loh Solomon K Musani Sobha Puppala William R Scott Loïc Yengo Sian-Tsung Tan Herman A Taylor Farook Thameem Gregory Wilson Tien Yin Wong Pål Rasmus Njølstad Jonathan C Levy Massimo Mangino Lori L Bonnycastle Thomas Schwarzmayr João Fadista Gabriela L Surdulescu Christian Herder Christopher J Groves Thomas Wieland Jette Bork-Jensen Ivan Brandslund Cramer Christensen Heikki A Koistinen Alex S F Doney Leena Kinnunen Tõnu Esko Andrew J Farmer Liisa Hakaste Dylan Hodgkiss Jasmina Kravic Valeri Lyssenko Mette Hollensted Marit E Jørgensen Torben Jørgensen Claes Ladenvall Johanne Marie Justesen Annemari Käräjämäki Jennifer Kriebel Wolfgang Rathmann Lars Lannfelt Torsten Lauritzen Narisu Narisu Allan Linneberg Olle Melander Lili Milani Matt Neville Marju Orho-Melander Lu Qi Qibin Qi Michael Roden Olov Rolandsson Amy Swift Anders H Rosengren Kathleen Stirrups Andrew R Wood Evelin Mihailov Christine Blancher Mauricio O Carneiro Jared Maguire Ryan Poplin Khalid Shakir Timothy Fennell Mark DePristo Martin Hrabé de Angelis Panos Deloukas Anette P Gjesing Goo Jun Peter Nilsson Jacquelyn Murphy Robert Onofrio Barbara Thorand Torben Hansen Christa Meisinger Frank B Hu Bo Isomaa Fredrik Karpe Liming Liang Annette Peters Cornelia Huth Stephen P O'Rahilly Colin N A Palmer Oluf Pedersen Rainer Rauramaa Jaakko Tuomilehto Veikko Salomaa Richard M Watanabe Ann-Christine Syvänen Richard N Bergman Dwaipayan Bharadwaj Erwin P Bottinger Yoon Shin Cho Giriraj R Chandak Juliana C N Chan Kee Seng Chia Mark J Daly Shah B Ebrahim Claudia Langenberg Paul Elliott Kathleen A Jablonski Donna M Lehman Weiping Jia Ronald C W Ma Toni I Pollin Manjinder Sandhu Nikhil Tandon Philippe Froguel Inês Barroso Yik Ying Teo Eleftheria Zeggini Ruth J F Loos Kerrin S Small Janina S Ried Ralph A DeFronzo Harald Grallert Benjamin Glaser Andres Metspalu Nicholas J Wareham Mark Walker Eric Banks Christian Gieger Erik Ingelsson Hae Kyung Im Thomas Illig Paul W Franks Gemma Buck Joseph Trakalo David Buck Inga Prokopenko Reedik Mägi Lars Lind Yossi Farjoun Katharine R Owen Anna L Gloyn Konstantin Strauch Tiinamaija Tuomi Jaspal Singh Kooner Jong-Young Lee Taesung Park Peter Donnelly Andrew D Morris Andrew T Hattersley Donald W Bowden Francis S Collins Gil Atzmon John C Chambers Timothy D Spector Markku Laakso Tim M Strom Graeme I Bell John Blangero Ravindranath Duggirala E Shyong Tai Gilean McVean Craig L Hanis James G Wilson Mark Seielstad Timothy M Frayling James B Meigs Nancy J Cox Rob Sladek Eric S Lander Stacey Gabriel Karen L Mohlke Thomas Meitinger Leif Groop Goncalo Abecasis Laura J Scott Andrew P Morris Hyun Min Kang David Altshuler Noël P Burtt Jose C Florez Michael Boehnke Mark I McCarthy

Sci Data 2018 01 23;5:180002. Epub 2018 Jan 23.

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http://dx.doi.org/10.1038/sdata.2018.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5779067PMC
January 2018

High-throughput extraction and quantification method for targeted metabolomics in murine tissues.

Metabolomics 2018 30;14(1):18. Epub 2017 Dec 30.

Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Experimental Genetics, Genome Analysis Center, Ingolstaedter Landstrasse 1, 85764, Neuherberg, Germany.

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http://dx.doi.org/10.1007/s11306-017-1312-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748028PMC
December 2017

Animal models of obesity and diabetes mellitus.

Nat Rev Endocrinol 2018 03 19;14(3):140-162. Epub 2018 Jan 19.

Institute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Ingolstädter Landstr. 1, D-85764 Neuherberg, Germany.

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http://dx.doi.org/10.1038/nrendo.2017.161DOI Listing
March 2018

Identification of genetic elements in metabolism by high-throughput mouse phenotyping.

Nat Commun 2018 01 18;9(1):288. Epub 2018 Jan 18.

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.

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http://dx.doi.org/10.1038/s41467-017-01995-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773596PMC
January 2018

The effect of differentiation and TGFβ on mitochondrial respiration and mitochondrial enzyme abundance in cultured primary human skeletal muscle cells.

Sci Rep 2018 01 15;8(1):737. Epub 2018 Jan 15.

Division of Pathobiochemistry and Clinical Chemistry, Department of Internal Medicine IV, University Hospital Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1038/s41598-017-18658-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768688PMC
January 2018

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.

Authors:
Jason Flannick Christian Fuchsberger Anubha Mahajan Tanya M Teslovich Vineeta Agarwala Kyle J Gaulton Lizz Caulkins Ryan Koesterer Clement Ma Loukas Moutsianas Davis J McCarthy Manuel A Rivas John R B Perry Xueling Sim Thomas W Blackwell Neil R Robertson N William Rayner Pablo Cingolani Adam E Locke Juan Fernandez Tajes Heather M Highland Josee Dupuis Peter S Chines Cecilia M Lindgren Christopher Hartl Anne U Jackson Han Chen Jeroen R Huyghe Martijn van de Bunt Richard D Pearson Ashish Kumar Martina Müller-Nurasyid Niels Grarup Heather M Stringham Eric R Gamazon Jaehoon Lee Yuhui Chen Robert A Scott Jennifer E Below Peng Chen Jinyan Huang Min Jin Go Michael L Stitzel Dorota Pasko Stephen C J Parker Tibor V Varga Todd Green Nicola L Beer Aaron G Day-Williams Teresa Ferreira Tasha Fingerlin Momoko Horikoshi Cheng Hu Iksoo Huh Mohammad Kamran Ikram Bong-Jo Kim Yongkang Kim Young Jin Kim Min-Seok Kwon Juyoung Lee Selyeong Lee Keng-Han Lin Taylor J Maxwell Yoshihiko Nagai Xu Wang Ryan P Welch Joon Yoon Weihua Zhang Nir Barzilai Benjamin F Voight Bok-Ghee Han Christopher P Jenkinson Teemu Kuulasmaa Johanna Kuusisto Alisa Manning Maggie C Y Ng Nicholette D Palmer Beverley Balkau Alena Stančáková Hanna E Abboud Heiner Boeing Vilmantas Giedraitis Dorairaj Prabhakaran Omri Gottesman James Scott Jason Carey Phoenix Kwan George Grant Joshua D Smith Benjamin M Neale Shaun Purcell Adam S Butterworth Joanna M M Howson Heung Man Lee Yingchang Lu Soo-Heon Kwak Wei Zhao John Danesh Vincent K L Lam Kyong Soo Park Danish Saleheen Wing Yee So Claudia H T Tam Uzma Afzal David Aguilar Rector Arya Tin Aung Edmund Chan Carmen Navarro Ching-Yu Cheng Domenico Palli Adolfo Correa Joanne E Curran Dennis Rybin Vidya S Farook Sharon P Fowler Barry I Freedman Michael Griswold Daniel Esten Hale Pamela J Hicks Chiea-Chuen Khor Satish Kumar Benjamin Lehne Dorothée Thuillier Wei Yen Lim Jianjun Liu Marie Loh Solomon K Musani Sobha Puppala William R Scott Loïc Yengo Sian-Tsung Tan Herman A Taylor Farook Thameem Gregory Wilson Tien Yin Wong Pål Rasmus Njølstad Jonathan C Levy Massimo Mangino Lori L Bonnycastle Thomas Schwarzmayr João Fadista Gabriela L Surdulescu Christian Herder Christopher J Groves Thomas Wieland Jette Bork-Jensen Ivan Brandslund Cramer Christensen Heikki A Koistinen Alex S F Doney Leena Kinnunen Tõnu Esko Andrew J Farmer Liisa Hakaste Dylan Hodgkiss Jasmina Kravic Valeri Lyssenko Mette Hollensted Marit E Jørgensen Torben Jørgensen Claes Ladenvall Johanne Marie Justesen Annemari Käräjämäki Jennifer Kriebel Wolfgang Rathmann Lars Lannfelt Torsten Lauritzen Narisu Narisu Allan Linneberg Olle Melander Lili Milani Matt Neville Marju Orho-Melander Lu Qi Qibin Qi Michael Roden Olov Rolandsson Amy Swift Anders H Rosengren Kathleen Stirrups Andrew R Wood Evelin Mihailov Christine Blancher Mauricio O Carneiro Jared Maguire Ryan Poplin Khalid Shakir Timothy Fennell Mark DePristo Martin Hrabé de Angelis Panos Deloukas Anette P Gjesing Goo Jun Peter Nilsson Jacquelyn Murphy Robert Onofrio Barbara Thorand Torben Hansen Christa Meisinger Frank B Hu Bo Isomaa Fredrik Karpe Liming Liang Annette Peters Cornelia Huth Stephen P O'Rahilly Colin N A Palmer Oluf Pedersen Rainer Rauramaa Jaakko Tuomilehto Veikko Salomaa Richard M Watanabe Ann-Christine Syvänen Richard N Bergman Dwaipayan Bharadwaj Erwin P Bottinger Yoon Shin Cho Giriraj R Chandak Juliana Cn Chan Kee Seng Chia Mark J Daly Shah B Ebrahim Claudia Langenberg Paul Elliott Kathleen A Jablonski Donna M Lehman Weiping Jia Ronald C W Ma Toni I Pollin Manjinder Sandhu Nikhil Tandon Philippe Froguel Inês Barroso Yik Ying Teo Eleftheria Zeggini Ruth J F Loos Kerrin S Small Janina S Ried Ralph A DeFronzo Harald Grallert Benjamin Glaser Andres Metspalu Nicholas J Wareham Mark Walker Eric Banks Christian Gieger Erik Ingelsson Hae Kyung Im Thomas Illig Paul W Franks Gemma Buck Joseph Trakalo David Buck Inga Prokopenko Reedik Mägi Lars Lind Yossi Farjoun Katharine R Owen Anna L Gloyn Konstantin Strauch Tiinamaija Tuomi Jaspal Singh Kooner Jong-Young Lee Taesung Park Peter Donnelly Andrew D Morris Andrew T Hattersley Donald W Bowden Francis S Collins Gil Atzmon John C Chambers Timothy D Spector Markku Laakso Tim M Strom Graeme I Bell John Blangero Ravindranath Duggirala E Shyong Tai Gilean McVean Craig L Hanis James G Wilson Mark Seielstad Timothy M Frayling James B Meigs Nancy J Cox Rob Sladek Eric S Lander Stacey Gabriel Karen L Mohlke Thomas Meitinger Leif Groop Goncalo Abecasis Laura J Scott Andrew P Morris Hyun Min Kang David Altshuler Noël P Burtt Jose C Florez Michael Boehnke Mark I McCarthy

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