Martin Hasselblatt

Martin Hasselblatt

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Martin Hasselblatt

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Magnetic resonance imaging surrogates of molecular subgroups in atypical teratoid/rhabdoid tumor.

Neuro Oncol 2018 11;20(12):1672-1679

Reference Center for Neuroradiology, Institute for Diagnostic and Interventional Neuroradiology, University Hospital of Würzburg, Würzburg, Germany.

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https://academic.oup.com/neuro-oncology/advance-article/doi/
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http://dx.doi.org/10.1093/neuonc/noy111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231209PMC
November 2018

Diffuse Astrocytoma, IDH-Wildtype: A Dissolving Diagnosis.

J Neuropathol Exp Neurol 2018 06;77(6):422-425

Institute of Neuropathology, University Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1093/jnen/nly012DOI Listing
June 2018

DNA methylation-based classification of central nervous system tumours.

Authors:
David Capper David T W Jones Martin Sill Volker Hovestadt Daniel Schrimpf Dominik Sturm Christian Koelsche Felix Sahm Lukas Chavez David E Reuss Annekathrin Kratz Annika K Wefers Kristin Huang Kristian W Pajtler Leonille Schweizer Damian Stichel Adriana Olar Nils W Engel Kerstin Lindenberg Patrick N Harter Anne K Braczynski Karl H Plate Hildegard Dohmen Boyan K Garvalov Roland Coras Annett Hölsken Ekkehard Hewer Melanie Bewerunge-Hudler Matthias Schick Roger Fischer Rudi Beschorner Jens Schittenhelm Ori Staszewski Khalida Wani Pascale Varlet Melanie Pages Petra Temming Dietmar Lohmann Florian Selt Hendrik Witt Till Milde Olaf Witt Eleonora Aronica Felice Giangaspero Elisabeth Rushing Wolfram Scheurlen Christoph Geisenberger Fausto J Rodriguez Albert Becker Matthias Preusser Christine Haberler Rolf Bjerkvig Jane Cryan Michael Farrell Martina Deckert Jürgen Hench Stephan Frank Jonathan Serrano Kasthuri Kannan Aristotelis Tsirigos Wolfgang Brück Silvia Hofer Stefanie Brehmer Marcel Seiz-Rosenhagen Daniel Hänggi Volkmar Hans Stephanie Rozsnoki Jordan R Hansford Patricia Kohlhof Bjarne W Kristensen Matt Lechner Beatriz Lopes Christian Mawrin Ralf Ketter Andreas Kulozik Ziad Khatib Frank Heppner Arend Koch Anne Jouvet Catherine Keohane Helmut Mühleisen Wolf Mueller Ute Pohl Marco Prinz Axel Benner Marc Zapatka Nicholas G Gottardo Pablo Hernáiz Driever Christof M Kramm Hermann L Müller Stefan Rutkowski Katja von Hoff Michael C Frühwald Astrid Gnekow Gudrun Fleischhack Stephan Tippelt Gabriele Calaminus Camelia-Maria Monoranu Arie Perry Chris Jones Thomas S Jacques Bernhard Radlwimmer Marco Gessi Torsten Pietsch Johannes Schramm Gabriele Schackert Manfred Westphal Guido Reifenberger Pieter Wesseling Michael Weller Vincent Peter Collins Ingmar Blümcke Martin Bendszus Jürgen Debus Annie Huang Nada Jabado Paul A Northcott Werner Paulus Amar Gajjar Giles W Robinson Michael D Taylor Zane Jaunmuktane Marina Ryzhova Michael Platten Andreas Unterberg Wolfgang Wick Matthias A Karajannis Michel Mittelbronn Till Acker Christian Hartmann Kenneth Aldape Ulrich Schüller Rolf Buslei Peter Lichter Marcel Kool Christel Herold-Mende David W Ellison Martin Hasselblatt Matija Snuderl Sebastian Brandner Andrey Korshunov Andreas von Deimling Stefan M Pfister

Nature 2018 03 14;555(7697):469-474. Epub 2018 Mar 14.

Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature26000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093218PMC
March 2018

Reduced histone H3 K27 trimethylation is encountered in about 50% of atypical teratoid/rhabdoid tumors (AT/RT) but is not associated with molecular subgroup status and outcome.

Acta Neuropathol 2017 11 16;134(5):817-818. Epub 2017 Aug 16.

Swabian Children's Cancer Center, Children's Hospital Augsburg and EU-RHAB Registry, Augsburg, Germany.

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http://dx.doi.org/10.1007/s00401-017-1766-yDOI Listing
November 2017

Abstracts of the 52nd Workshop for Pediatric Research : Frankfurt, Germany. 27-28 October 2016.

Authors:
Rhea van den Bruck Patrick P Weil Thomas Ziegenhals Philipp Schreiner Stefan Juranek Daniel Gödde Silvia Vogel Frauke Schuster Valerie Orth Johannes Dörner Daniel Pembaur Meike Röper Stefan Störkel Hubert Zirngibl Stefan Wirth Andreas C W Jenke Jan Postberg Nikolas Boy Jana Heringer Gisela Haege Esther M Glahn Georg F Hoffmann Sven F Garbade Peter Burgard Stefan Kölker Cho-Ming Chao Faady Yahya Alena Moiseenko Amit Shrestha Negah Ahmadvand Jennifer Quantius Jochen Wilhelm Elie El-Agha Klaus-Peter Zimmer Saverio Bellusci Christian Staufner Stefan Kölker Holger Prokisch Georg F Hoffmann Stephan Seeliger Matthias Müller Andreas Hippe Henrik Steinkraus Roland Wauer Burkhard Lachmann Sigrun R Hofmann Christian M Hedrich Jakob Zierk Farhad Arzideh Rainer Haeckel Wolfgang Rascher Manfred Rauh Markus Metzler Sebastian Thieme Joanna Bandoła Cornelia Richter Martin Ryser Arshad Jamal Michelle P Ashton Malte von Bonin Matthias Kuhn Christian M Hedrich Ezio Bonifacio Reinhard Berner Sebastian Brenner Johanna Hammersen Cristina Has Nora Naumann-Bartsch Daniel Stachel Dimitra Kiritsi Stephan Söder Mathilde Tardieu Markus Metzler Leena Bruckner-Tuderman Holm Schneider F Bohne D Langer R Cencic T Eggermann U Zechner J Pelletier F Zepp T Enklaar D Prawitt Martin Pech Markus Weckmann Femke-Anouska Heinsen Andre Franke Christine Happle Anna-Maria Dittrich Gesine Hansen Oliver Fuchs Erika von Mutius Brian G Oliver Matthias V Kopp Claudia Paret Alexandra Russo Johanna Theruvath Bettina Keller Khalifa El Malki Nadine Lehmann Arthur Wingerter Marie A Neu Gerhold-Ay Aslihan Wolfgang Wagner Clemens Sommer Torsten Pietsch Larissa Seidmann Jörg Faber Felix Schreiner Merle Ackermann Michael Michalik Eva Rother Andras Bilkei-Gorzo Ildiko Racz Laura Bindila Beat Lutz Jörg Dötsch Andreas Zimmer Joachim Woelfle Hendrik S Fischer Tim L Ullrich Christoph Bührer Christoph Czernik Gerd Schmalisch Robert Stein Sigrun R Hofmann Judith Hagenbuchner Ursula Kiechl-Kohlendorfer Petra Obexer Michael J Ausserlechner Niki T Loges Adrien Tobias Frommer Julia Wallmeier Heymut Omran Soner Öner-Sieben Martina Gimpfl Jan Rozman Martin Irmler Johannes Beckers Martin Hrabe De Angelis Adelbert Roscher Eckhard Wolf Regina Ensenauer Karolina Nemes Michael Frühwald Martin Hasselblatt Reiner Siebert Uwe Kordes Marcel Kool Haicui Wang Holly Hardy Osama Refai Katy E S Barwick Holly H Zimmerman Joachim Weis Emma L Baple Andrew H Crosby Sebahattin Cirak C Hellmuth O Uhl M Standl J Heinrich E Thiering B Koletzko Lena Blümel Kornelius Kerl Daniel Picard Michael C Frühwald Max C Liebau Guido Reifenberger Arndt Borkhardt Martin Hasselblatt Marc Remke D Tews M Wabitsch P Fischer-Posovszky Mike-Andrew Westhoff Lisa Nonnenmacher Julia Langhans Lukas Schneele Nancy Trenkler Klaus-Michael Debatin

Mol Cell Pediatr 2017 May;4(Suppl 1)

Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.

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http://dx.doi.org/10.1186/s40348-017-0071-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435609PMC
May 2017

Atypical teratoid/rhabdoid tumor arising in a malignant glioma.

Pediatr Blood Cancer 2017 01 29;64(1):96-99. Epub 2016 Jul 29.

2nd Department of Pediatrics, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.1002/pbc.26173DOI Listing
January 2017

hTERT promoter methylation in meningiomas and central nervous hemangiopericytomas.

J Neurooncol 2016 10 27;130(1):79-87. Epub 2016 Jul 27.

Department of Neurosurgery, University Hospital Münster, Albert-Schweitzer-Campus 1, Building A1, 48149, Münster, Germany.

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http://dx.doi.org/10.1007/s11060-016-2226-6DOI Listing
October 2016

Choroid plexus papilloma in a beluga whale (Delphinapterus leucas).

J Vet Diagn Invest 2016 Jul 22;28(4):461-3. Epub 2016 May 22.

Institute of Neuropathology, University Hospital Münster, Münster, Germany (Thomas, Paulus, Hasselblatt)Niagara Falls Animal Medical Centre, Niagara Falls, Ontario, Canada (Mergl, Gehring)Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Montreal, Quebec, Canada (Martineau)

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http://dx.doi.org/10.1177/1040638716651112DOI Listing
July 2016

CD4+ T effector memory cell dysfunction is associated with the accumulation of granulocytic myeloid-derived suppressor cells in glioblastoma patients.

Neuro Oncol 2016 06 17;18(6):807-18. Epub 2015 Nov 17.

Department of Neurology, University Hospital of Regensburg, Regensburg, Germany (D.D., U.B.); Department of Neurosurgery, University Hospital of Muenster, Muenster, Germany (J.W., W.S.); Institute of Neuropathology, University Hospital of Muenster, Muenster, Germany (M.H.); Department of Neurology, University Hospital of Muenster, Muenster, Germany (T.S.-H., H.W., O.M.G.).

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http://dx.doi.org/10.1093/neuonc/nov280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864257PMC
June 2016

Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups.

Neuro Oncol 2016 06 28;18(6):790-6. Epub 2016 Jan 28.

Institute of Neuropathology, University Hospital Münster, Münster, Germany (C.T., V.R., A.J., W.P., M.H.); Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany (M.S.); Core Facility Genomics of the Medical Faculty Münster, Münster, Germany (A.W.); Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany (S.H., U.K.); Department of Neuropathology, Institute for Pathology and Neuropathology, University of Tübingen, Tübingen, Germany (R.B.); Faculty of Medicine, Institute of Neuropathology, University of Duisburg-Essen, Essen, Germany (K.K.); Department of Neuropathology, Klinikum Bremen-Mitte, Bremen, Germany (M.B.); Institute of Neurology (Edinger Institute), Goethe University, Frankfurt, Germany (M.M.); Institute of Neuropathology, University of Bonn Medical Center, Bonn, Germany (T.P.); Department of Neuropathology, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany (J.F.); Department of Neuropathology, Institute of Pathology, University of Würzburg, and Comprehensive Cancer Center Mainfranken (CCCM), Würzburg, Germany (C.M.M.); Department of Neuropathology, Sainte-Anne Hospital, Paris, France (P.V.); 2nd Department of Paediatrics, Semmelweis University, Budapest, Hungary (P.H.); Department of Hematopathology, Molecular Diagnostic Laboratory, The University of Texas MD Anderson Cancer Center, Houston, Texas (A.O.); Children's Brain Tumour Research Centre, School of Medicine, Queen's Medical Centre, University of Nottingham, Nottingham, UK (R.G.G.); Department of Pediatric Hematology Oncology and Blood and Marrow Transplantation, Cleveland Clinic Children's Hospital, Cleveland, Ohio (J.E.W.); Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany (A.K., A.v.D., D.C.); Clinical Cooperation Unit Neuropathology, German Research Center (DKFZ), Heidelberg, Germany (A.K., A.v.D., D.C.); German Cancer Consortium (DKTK), German Cancer Research Ce

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http://dx.doi.org/10.1093/neuonc/nov322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864264PMC
June 2016

The influence of clinical and genetic factors on patient outcome in small cell carcinoma of the ovary, hypercalcemic type.

Gynecol Oncol 2016 06 19;141(3):454-460. Epub 2016 Mar 19.

Department of Human Genetics, McGill University, Montreal, QC, Canada; Lady Davis Institute and Segal Cancer Center, Jewish General Hospital, Montreal, QC, Canada; Department of Medical Genetics and Cancer Research Program, Research Institute, McGill University Health Centre, Montreal, QC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2016.03.013DOI Listing
June 2016

The Value of 5-Aminolevulinic Acid in Low-grade Gliomas and High-grade Gliomas Lacking Glioblastoma Imaging Features: An Analysis Based on Fluorescence, Magnetic Resonance Imaging, 18F-Fluoroethyl Tyrosine Positron Emission Tomography, and Tumor Molecular Factors.

Neurosurgery 2016 Mar;78(3):401-11; discussion 411

‡Department of Neurosurgery, University Hospital Münster, Münster, Germany;§Institute of Neuropathology, University Hospital Münster, Münster, Germany;¶Institute for Clinical Radiology, University Hospital of Münster, Münster, Germany;‖Department of Nuclear Medicine, University Hospital of Münster, Münster, Germany.

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https://academic.oup.com/neurosurgery/article-lookup/doi/10.
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http://dx.doi.org/10.1227/NEU.0000000000001020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747980PMC
March 2016

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs.

Authors:
Dominik Sturm Brent A Orr Umut H Toprak Volker Hovestadt David T W Jones David Capper Martin Sill Ivo Buchhalter Paul A Northcott Irina Leis Marina Ryzhova Christian Koelsche Elke Pfaff Sariah J Allen Gnanaprakash Balasubramanian Barbara C Worst Kristian W Pajtler Sebastian Brabetz Pascal D Johann Felix Sahm Jüri Reimand Alan Mackay Diana M Carvalho Marc Remke Joanna J Phillips Arie Perry Cynthia Cowdrey Rachid Drissi Maryam Fouladi Felice Giangaspero Maria Łastowska Wiesława Grajkowska Wolfram Scheurlen Torsten Pietsch Christian Hagel Johannes Gojo Daniela Lötsch Walter Berger Irene Slavc Christine Haberler Anne Jouvet Stefan Holm Silvia Hofer Marco Prinz Catherine Keohane Iris Fried Christian Mawrin David Scheie Bret C Mobley Matthew J Schniederjan Mariarita Santi Anna M Buccoliero Sonika Dahiya Christof M Kramm André O von Bueren Katja von Hoff Stefan Rutkowski Christel Herold-Mende Michael C Frühwald Till Milde Martin Hasselblatt Pieter Wesseling Jochen Rößler Ulrich Schüller Martin Ebinger Jens Schittenhelm Stephan Frank Rainer Grobholz Istvan Vajtai Volkmar Hans Reinhard Schneppenheim Karel Zitterbart V Peter Collins Eleonora Aronica Pascale Varlet Stephanie Puget Christelle Dufour Jacques Grill Dominique Figarella-Branger Marietta Wolter Martin U Schuhmann Tarek Shalaby Michael Grotzer Timothy van Meter Camelia-Maria Monoranu Jörg Felsberg Guido Reifenberger Matija Snuderl Lynn Ann Forrester Jan Koster Rogier Versteeg Richard Volckmann Peter van Sluis Stephan Wolf Tom Mikkelsen Amar Gajjar Kenneth Aldape Andrew S Moore Michael D Taylor Chris Jones Nada Jabado Matthias A Karajannis Roland Eils Matthias Schlesner Peter Lichter Andreas von Deimling Stefan M Pfister David W Ellison Andrey Korshunov Marcel Kool

Cell 2016 Feb;164(5):1060-1072

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), 69120 Heidelberg, Germany.

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http://www.cell.com/cell/pdf/S0092-8674(16)00055-6.pdf
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http://www.cell.com/cms/attachment/2048488015/2058390163/mmc
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http://linkinghub.elsevier.com/retrieve/pii/S009286741600055
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http://dx.doi.org/10.1016/j.cell.2016.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139621PMC
February 2016

hTERT promoter methylation in pituitary adenomas.

Brain Tumor Pathol 2016 Jan 21;33(1):27-34. Epub 2015 Sep 21.

Department of Neurosurgery, University Hospital Münster, Albert-Schweitzer-Campus 1, A1, 48149, Münster, Germany.

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http://dx.doi.org/10.1007/s10014-015-0230-8DOI Listing
January 2016

SonoGraphic monitoring of severe focal B-cell myositis of the anterior calf muscle responsive to rituximab.

Muscle Nerve 2015 Nov;52(5):911-3

Department of Neurology, St. Josef-Hospital, Ruhr-University Bochum, Bochum, Germany.

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http://dx.doi.org/10.1002/mus.24751DOI Listing
November 2015

Pediatric atypical choroid plexus papilloma reconsidered: increased mitotic activity is prognostic only in older children.

Acta Neuropathol 2015 Jun 3;129(6):925-7. Epub 2015 May 3.

Institute of Neuropathology, University Hospital Münster, Pottkamp 2, 48149, Münster, Germany.

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http://dx.doi.org/10.1007/s00401-015-1434-zDOI Listing
June 2015

Prophylactic oophorectomy for hereditary small cell carcinoma of the ovary, hypercalcemic type.

Gynecol Oncol Rep 2015 Apr 25;12:20-2. Epub 2015 Feb 25.

Department of Human Genetics, McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.1016/j.gore.2015.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442656PMC
April 2015

Primary rhabdoid tumor of the ovary: When large cells become small cells.

Gynecol Oncol Rep 2015 Apr 19;12:64-6. Epub 2015 Mar 19.

Department of Medical Genetics, Lady Davis Institute and Segal Cancer Centre, Jewish General Hospital, McGill University, Montreal, QC, Canada ; Department of Human Genetics, McGill University, Montreal, QC, Canada ; Department of Medical Genetics, Research Institute, McGill University Health Centre, Montreal, QC, Canada.

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http://dx.doi.org/10.1016/j.gore.2015.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442655PMC
April 2015

A comparative analysis of MAPK pathway hallmark alterations in pilocytic astrocytomas: age-related and mutually exclusive. [corrected].

Neuropathol Appl Neurobiol 2015 Feb;41(2):258-61

Department of Neurosurgery, University Hospital Münster, Münster, Germany; Institute of Neuropathology, University Hospital Münster, Münster, Germany.

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http://doi.wiley.com/10.1111/nan.12145
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http://dx.doi.org/10.1111/nan.12145DOI Listing
February 2015

Germline SMARCE1 mutations predispose to both spinal and cranial clear cell meningiomas.

J Pathol 2014 Dec 6;234(4):436-40. Epub 2014 Oct 6.

Manchester Centre for Genomic Medicine, University of Manchester, Manchester Academic Health Sciences Centre (MAHSC), UK.

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http://dx.doi.org/10.1002/path.4427DOI Listing
December 2014

Loss of endoplasmic reticulum calcium pump expression in choroid plexus tumours.

Neuropathol Appl Neurobiol 2014 Oct;40(6):726-35

Institut National de la Santé et de la Recherche Médicale, UMR U978, Bobigny, France; Université Paris-13, PRES Sorbonne Paris-Cité, Bobigny, France.

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http://doi.wiley.com/10.1111/nan.12098
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http://dx.doi.org/10.1111/nan.12098DOI Listing
October 2014

Identifying molecular markers for the sensitive detection of residual atypical teratoid rhabdoid tumor cells.

Cancer Genet 2014 Sep 21;207(9):390-7. Epub 2014 May 21.

Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22107762140009
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http://dx.doi.org/10.1016/j.cancergen.2014.05.008DOI Listing
September 2014

Synchronous congenital malignant rhabdoid tumor of the orbit and atypical teratoid/rhabdoid tumor--feasibility and efficacy of multimodal therapy in a long-term survivor.

Cancer Genet 2014 Sep 3;207(9):429-33. Epub 2014 Jul 3.

Swabian Children's Cancer Center, Children's Hospital Augsburg, Augsburg, Germany; Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2014.06.028DOI Listing
September 2014

Methylation of the hTERT promoter is frequent in choroid plexus tumors but not of independent prognostic value.

J Neurooncol 2014 Aug 14;119(1):215-6. Epub 2014 May 14.

Institute of Neuropathology, University Hospital Münster, Pottkamp 2, 48149, Münster, Germany.

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http://dx.doi.org/10.1007/s11060-014-1473-7DOI Listing
August 2014

No small surprise - small cell carcinoma of the ovary, hypercalcaemic type, is a malignant rhabdoid tumour.

J Pathol 2014 Jul 20;233(3):209-14. Epub 2014 May 20.

Department of Medical Genetics, Lady Davis Institute and Segal Cancer Centre, Jewish General Hospital, McGill University, Montreal, QC, Canada; Department of Human Genetics, McGill University, Montreal, QC, Canada; Department of Medical Genetics, Research Institute, McGill University Health Centre, Montreal, QC, Canada.

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http://dx.doi.org/10.1002/path.4362DOI Listing
July 2014

Favorable outcome of patients affected by rhabdoid tumors due to rhabdoid tumor predisposition syndrome (RTPS).

Pediatr Blood Cancer 2014 May 3;61(5):919-21. Epub 2013 Oct 3.

Department of Pediatric Hematology and Oncology, University Medical Center Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1002/pbc.24793DOI Listing
May 2014

Choroid plexus carcinomas are characterized by complex chromosomal alterations related to patient age and prognosis.

Genes Chromosomes Cancer 2014 May 30;53(5):373-80. Epub 2014 Jan 30.

Institute of Neuropathology, University Hospital Münster, Münster, Germany.

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http://doi.wiley.com/10.1002/gcc.22148
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http://dx.doi.org/10.1002/gcc.22148DOI Listing
May 2014

Germline and somatic SMARCA4 mutations characterize small cell carcinoma of the ovary, hypercalcemic type.

Nat Genet 2014 May 23;46(5):438-43. Epub 2014 Mar 23.

1] Program in Cancer Genetics, Department of Oncology and Human Genetics, McGill University, Montreal, Quebec, Canada. [2] Department of Medical Genetics, Lady Davis Institute and Segal Cancer Centre, Jewish General Hospital, McGill University, Montreal, Quebec, Canada. [3] Department of Human Genetics, McGill University, Montreal, Quebec, Canada. [4] Department of Medical Genetics, Research Institute, McGill University Health Centre, Montreal, Quebec, Canada.

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http://www.nature.com/articles/ng.2931
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http://dx.doi.org/10.1038/ng.2931DOI Listing
May 2014

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition.

Cancer Cell 2014 Mar;25(3):393-405

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), 69121 Heidelberg, Germany; Department of Pediatric Oncology, Hematology and Immunology, University Hospital Heidelberg, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ccr.2014.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493053PMC
March 2014

Increased mitotic and proliferative activity are associated with worse prognosis in papillary tumors of the pineal region.

Am J Surg Pathol 2014 Jan;38(1):106-10

*Institute of Neuropathology, University Hospital Münster, Münster †Department of Neuropathology, Institute for Pathology and Neuropathology, University of Tübingen, Tübingen ‡Institute of Neurology (Edinger Institute), Goethe University, Frankfurt §Institute of Pathology and Neuropathology, University Hospital Essen, Essen ∥Department of Neuropathology, Regensburg University Hospital, Regensburg #Department of Neuropathology, Institute of Pathology, Hannover Medical School, Hannover **Institute of Neuropathology, Justus Liebig University, Giessen ††Department of Neuropathology, University Hospital Erlangen, Erlangen, Germany ¶Department of Clinical Pathology, Section of Neuropathology, Institute of Pathology, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1097/PAS.0b013e31829e492dDOI Listing
January 2014

Papillary tumor of the pineal region with anaplastic small cell component.

J Neurooncol 2013 Oct 2;115(1):127-30. Epub 2013 Jul 2.

Institute of Neuropathology, University Hospital Münster, Pottkamp 2, 48149, Münster, Germany.

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http://dx.doi.org/10.1007/s11060-013-1202-7DOI Listing
October 2013

Somatostatin receptor subtype 2 (sst₂) is a potential prognostic marker and a therapeutic target in medulloblastoma.

Childs Nerv Syst 2013 Aug 16;29(8):1253-62. Epub 2013 May 16.

Division of Neurosurgery, Arthur and Sonia Labatt Brain Tumor Research Centre, Program in Developmental and Stem Cell Biology, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s00381-013-2142-4DOI Listing
August 2013

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.

Nat Genet 2013 Aug 30;45(8):927-32. Epub 2013 Jun 30.

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://pubman.mpdl.mpg.de/pubman/item/escidoc:1982973/compon
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http://www.nature.com/doifinder/10.1038/ng.2682
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http://dx.doi.org/10.1038/ng.2682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951336PMC
August 2013

DNA copy number alterations in central primitive neuroectodermal tumors and tumors of the pineal region: an international individual patient data meta-analysis.

J Neurooncol 2012 Sep 7;109(2):415-23. Epub 2012 Jul 7.

Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.

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http://dx.doi.org/10.1007/s11060-012-0911-7DOI Listing
September 2012

Dissecting the genomic complexity underlying medulloblastoma.

Nature 2012 Aug;488(7409):100-5

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg 69120, Germany.

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http://dx.doi.org/10.1038/nature11284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662966PMC
August 2012

TET2 promoter methylation in low-grade diffuse gliomas lacking IDH1/2 mutations.

J Clin Pathol 2011 Oct 20;64(10):850-2. Epub 2011 Jun 20.

International Agency for Research on Cancer, Lyon, France.

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http://dx.doi.org/10.1136/jclinpath-2011-200133DOI Listing
October 2011

Claudin-6 is of limited sensitivity and specificity for the diagnosis of atypical teratoid/rhabdoid tumors.

Brain Pathol 2011 Sep 16;21(5):558-63. Epub 2011 Mar 16.

Department of Radiology, Oncology and Anatomic-pathology Sciences, Sapienza University, Rome, Italy.

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http://dx.doi.org/10.1111/j.1750-3639.2011.00478.xDOI Listing
September 2011

Role of neoadjuvant chemotherapy in congenital intracranial haemangiopericytoma.

Pediatr Blood Cancer 2011 Jan;56(1):161-3

Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1002/pbc.22726DOI Listing
January 2011

Molecular diagnostics of CNS embryonal tumors.

Acta Neuropathol 2010 Nov 30;120(5):553-66. Epub 2010 Sep 30.

German Cancer Research Center, Heidelberg, Germany.

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http://link.springer.com/10.1007/s00401-010-0751-5
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http://dx.doi.org/10.1007/s00401-010-0751-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4512653PMC
November 2010

Partial amniotic carbon dioxide insufflation during minimally invasive fetoscopic interventions seems safe for the fetal brain in sheep.

J Laparoendosc Adv Surg Tech A 2010 Sep;20(7):651-3

German Center for Fetal Surgery and Minimally Invasive Therapy, University of Giessen , Giessen, Germany.

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http://www.liebertpub.com/doi/10.1089/lap.2010.0068
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http://dx.doi.org/10.1089/lap.2010.0068DOI Listing
September 2010

MGMT as a potential stratification marker in relapsed high-grade glioma of children: the HIT-GBM experience.

Pediatr Blood Cancer 2010 Feb;54(2):228-37

Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Germany.

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http://dx.doi.org/10.1002/pbc.22323DOI Listing
February 2010

Clinical and molecular features in patients with atypical teratoid rhabdoid tumor or malignant rhabdoid tumor.

Genes Chromosomes Cancer 2010 Feb;49(2):176-81

Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://doi.wiley.com/10.1002/gcc.20729
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http://dx.doi.org/10.1002/gcc.20729DOI Listing
February 2010

Role of Wnt inhibitory factor-1 and Wnt/wingless signaling in choroid plexus tumors.

Pediatr Blood Cancer 2009 Dec;53(6):1152-5

Institute of Neuropathology, University Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.1002/pbc.22201DOI Listing
December 2009

From glioblastoma to gangliocytoma: an unforeseen but welcome shift in biological behavior.

J Neurosurg Pediatr 2009 Nov;4(5):475-8

Institute of Neuropathology, University Hospital Münster, Heidelberg, Germany.

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http://dx.doi.org/10.3171/2009.6.PEDS097DOI Listing
November 2009