Martin Granzow

Department of Human Molecular Genetics, Institute of Human Genetics, University Heidelberg, Germany; DZHK, German Centre for Cardiovascular Research, Partner site Heidelberg/Mannheim, Germany. Electronic address:

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May 2017

DDX3X mutations in two girls with a phenotype overlapping Toriello-Carey syndrome.

Authors:

Nicola Dikow Martin Granzow Luitgard M Graul-Neumann Stephanie Karch Katrin Hinderhofer Nagarajan Paramasivam Laura-Jane Behl Lilian Kaufmann Christine Fischer Christina Evers Matthias Schlesner Roland Eils Guntram Borck Christiane Zweier Claus R Bartram John C Carey Ute Moog

Am J Med Genet A 2017 May 29;173(5):1369-1373. Epub 2017 Mar 29.

Institute of Human Genetics, Heidelberg University, Heidelberg, Germany.

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May 2017

Novel recurrent chromosomal aberrations detected in clonal plasma cells of light chain amyloidosis patients show potential adverse prognostic effect: first results from a genome-wide copy number array analysis.

Authors:

Martin Granzow Ute Hegenbart Katrin Hinderhofer Dirk Hose Anja Seckinger Tilmann Bochtler Kari Hemminki Hartmut Goldschmidt Stefan O Schönland Anna Jauch

Haematologica 2017 07 24;102(7):1281-1290. Epub 2017 Mar 24.

Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany.

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July 2017

Marker chromosomes can arise from chromothripsis and predict adverse prognosis in acute myeloid leukemia.

Blood 2017 03 24;129(10):1333-1342. Epub 2017 Jan 24.

Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center.

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March 2017

miR-16 and miR-125b are involved in barrier function dysregulation through the modulation of claudin-2 and cingulin expression in the jejunum in IBS with diarrhoea.

Gut 2017 09 12;66(9):1537-1538. Epub 2017 Jan 12.

Digestive System Research Unit, Institut de Recerca Vall d'Hebron, Barcelona, Spain.

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September 2017

Prognostic impact of cytogenetic aberrations in AL amyloidosis patients after high-dose melphalan: a long-term follow-up study.

Authors:

Tilmann Bochtler Ute Hegenbart Christina Kunz Axel Benner Christoph Kimmich Anja Seckinger Dirk Hose Hartmut Goldschmidt Martin Granzow Peter Dreger Anthony D Ho Anna Jauch Stefan O Schönland

Blood 2016 07 2;128(4):594-602. Epub 2016 Jun 2.

Amyloidosis Center, and Division of Hematology/Oncology/Rheumatology, Department of Internal Medicine, University of Heidelberg, Heidelberg, Germany;

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July 2016

Exome sequencing reveals a novel CWF19L1 mutation associated with intellectual disability and cerebellar atrophy.

Authors:

Christina Evers Lilian Kaufmann Angelika Seitz Nagarajan Paramasivam Martin Granzow Stephanie Karch Christine Fischer Katrin Hinderhofer Georg Gdynia Michael Elsässer Stefan Pinkert Matthias Schlesner Claus R Bartram Ute Moog

Am J Med Genet A 2016 06 26;170(6):1502-9. Epub 2016 Mar 26.

Institute of Human Genetics, Heidelberg University, Heidelberg, Germany.

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June 2016

Concomitant gain of 1q21 and MYC translocation define a poor prognostic subgroup of hyperdiploid multiple myeloma.

Authors:

Niels Weinhold Desiree Kirn Anja Seckinger Thomas Hielscher Martin Granzow Uta Bertsch Gerlinde Egerer Hans Salwender Igor W Blau Katja Weisel Jens Hillengass Marc S Raab Dirk Hose Hartmut Goldschmidt Anna Jauch

Haematologica 2016 Mar 26;101(3):e116-9. Epub 2015 Nov 26.

Institute of Human Genetics, University of Heidelberg, Germany.

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March 2016

Recurrent CDKN1B (p27) mutations in hairy cell leukemia.

Blood 2015 Aug 11;126(8):1005-8. Epub 2015 Jun 11.

Department of Medicine V, University Hospital Heidelberg, Department of Translational Oncology, National Center for Tumor Diseases and German Cancer Research Center (DKFZ), Heidelberg, Germany;

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August 2015

Glycodelin: A New Biomarker with Immunomodulatory Functions in Non-Small Cell Lung Cancer.

Authors:

Marc A Schneider Martin Granzow Arne Warth Philipp A Schnabel Michael Thomas Felix J F Herth Hendrik Dienemann Thomas Muley Michael Meister

Clin Cancer Res 2015 Aug 21;21(15):3529-40. Epub 2015 Apr 21.

Translational Research Unit, Thoraxklinik at University Hospital Heidelberg, Heidelberg, Germany. Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), Heidelberg, Germany.

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August 2015

SIPA1L3 identified by linkage analysis and whole-exome sequencing as a novel gene for autosomal recessive congenital cataract.

Authors:

Christina Evers Nagarajan Paramasivam Katrin Hinderhofer Christine Fischer Martin Granzow Annette Schmidt-Bacher Roland Eils Herbert Steinbeisser Matthias Schlesner Ute Moog

Eur J Hum Genet 2015 Dec 25;23(12):1627-33. Epub 2015 Mar 25.

Institute of Human Genetics, Heidelberg University, Heidelberg, Germany.

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December 2015

Translocation t(11;14) is associated with adverse outcome in patients with newly diagnosed AL amyloidosis when treated with bortezomib-based regimens.

Authors:

Tilmann Bochtler Ute Hegenbart Christina Kunz Martin Granzow Axel Benner Anja Seckinger Christoph Kimmich Hartmut Goldschmidt Anthony D Ho Dirk Hose Anna Jauch Stefan O Schönland

J Clin Oncol 2015 Apr 16;33(12):1371-8. Epub 2015 Mar 16.

Tilmann Bochtler, Ute Hegenbart, Anja Seckinger, Christoph Kimmich, Hartmut Goldschmidt, Anthony D. Ho, Dirk Hose, and Stefan O. Schönland, Amyloidosis Center, University Hospital Heidelberg; Christina Kunz and Axel Benner, German Cancer Research Center; Martin Granzow and Anna Jauch, Institute of Human Genetics, University Heidelberg; and Hartmut Goldschmidt and Dirk Hose, National Center for Tumor Diseases, Heidelberg, Germany.

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April 2015

3p25.3 microdeletion of GABA transporters SLC6A1 and SLC6A11 results in intellectual disability, epilepsy and stereotypic behavior.

Authors:

Nicola Dikow Bianca Maas Stephanie Karch Martin Granzow Johannes W G Janssen Anna Jauch Katrin Hinderhofer Christian Sutter Susanne Schubert-Bast Britt Marie Anderlid Bruno Dallapiccola Nathalie Van der Aa Ute Moog

Am J Med Genet A 2014 Dec 24;164A(12):3061-8. Epub 2014 Sep 24.

Institute of Human Genetics, Heidelberg University, Heidelberg, Germany.

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December 2014

Gain of chromosome 1q21 is an independent adverse prognostic factor in light chain amyloidosis patients treated with melphalan/dexamethasone.

Authors:

Tilmann Bochtler Ute Hegenbart Christina Kunz Axel Benner Anja Seckinger Sascha Dietrich Martin Granzow Kai Neben Hartmut Goldschmidt Anthony D Ho Dirk Hose Anna Jauch Stefan O Schönland

Amyloid 2014 Mar 23;21(1):9-17. Epub 2014 Jan 23.

Amyloidosis Center, Department of Internal Medicine, University of Heidelberg , Heidelberg, Germany .

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March 2014

Progression in smoldering myeloma is independently determined by the chromosomal abnormalities del(17p), t(4;14), gain 1q, hyperdiploidy, and tumor load.

Authors:

Kai Neben Anna Jauch Thomas Hielscher Jens Hillengass Nicola Lehners Anja Seckinger Martin Granzow Marc S Raab Anthony D Ho Hartmut Goldschmidt Dirk Hose

J Clin Oncol 2013 Dec 21;31(34):4325-32. Epub 2013 Oct 21.

Kai Neben, Anna Jauch, Jens Hillengass, Nicola Lehners, Martin Granzow, Marc S. Raab, and Anthony D. Ho, University of Heidelberg; Thomas Hielscher, German Cancer Research Center; and Anja Seckinger, Hartmut Goldschmidt, and Dirk Hose,University of Heidelberg and National Center for Tumor Diseases, Heidelberg, Germany.

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December 2013