Martin Graf

Martin Graf

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Martin Graf

Martin Graf

Publications by authors named "Martin Graf"

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Cell-Based Assays Using Differentiated Human Induced Pluripotent Cells.

Methods Mol Biol 2019 ;1994:1-14

Tissue Injury and Repair Group, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1007/978-1-4939-9477-9_1DOI Listing
January 2019

A vertebrate-specific and essential role for osterix in osteogenesis revealed by gene knockout in the teleost medaka.

Development 2017 01 19;144(2):265-271. Epub 2016 Dec 19.

Department of Biological Sciences, National University of Singapore, Singapore 117543, Singapore

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http://dx.doi.org/10.1242/dev.139550DOI Listing
January 2017

Establishment of a translational endothelial cell model using directed differentiation of induced pluripotent stem cells from Cynomolgus monkey.

Sci Rep 2016 10 25;6:35830. Epub 2016 Oct 25.

Roche pRED (Pharmaceutical Research and Early Development), Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Basel, Switzerland.

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http://dx.doi.org/10.1038/srep35830DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078800PMC
October 2016

Generation of functional podocytes from human induced pluripotent stem cells.

Stem Cell Res 2016 07 3;17(1):130-9. Epub 2016 Jun 3.

IRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Centro Anna Maria Astori, Science and Technology Park Kilometro Rosso, 24126 Bergamo, Italy.

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http://dx.doi.org/10.1016/j.scr.2016.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009184PMC
July 2016

mTORC1 Inhibition Corrects Neurodevelopmental and Synaptic Alterations in a Human Stem Cell Model of Tuberous Sclerosis.

Cell Rep 2016 Apr 24;15(1):86-95. Epub 2016 Mar 24.

Roche Pharmaceutical Research and Early Development, Neuroscience Ophthalmology and Rare Diseases Discovery & Translational Area, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., Grenzacherstrasse 124, 4070 Basel, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.02.090DOI Listing
April 2016

StemBANCC: Governing Access to Material and Data in a Large Stem Cell Research Consortium.

Stem Cell Rev Rep 2015 Oct;11(5):681-7

HeLEX - Centre for Health, Law and Emerging Technologies, Department of Public Health, University of Oxford, Old Road Campus, Oxford, OX3 7LF, UK,

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http://dx.doi.org/10.1007/s12015-015-9599-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561067PMC
October 2015

Generation of vascular endothelial and smooth muscle cells from human pluripotent stem cells.

Nat Cell Biol 2015 Aug 27;17(8):994-1003. Epub 2015 Jul 27.

1] Department of Stem Cell and Regenerative Biology and Harvard Stem Cell Institute, Harvard University, Massachusetts 02138, USA [2] Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA [3] Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute, Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/ncb3205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4566857PMC
August 2015

Dmrt5 controls corticotrope and gonadotrope differentiation in the zebrafish pituitary.

Mol Endocrinol 2015 Feb 9;29(2):187-99. Epub 2014 Dec 9.

Department of Biological Sciences and Centre for Bioimaging Sciences, National University of Singapore, Singapore 117543.

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http://dx.doi.org/10.1210/me.2014-1176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414757PMC
February 2015

Multicellular self-assembled spheroidal model of the blood brain barrier.

Sci Rep 2013 ;3:1500

Pharma Research and Early Development, Neuroscience DTA, F. Hoffmann-La Roche Basel, Switzerland.

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http://www.nature.com/articles/srep01500
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http://dx.doi.org/10.1038/srep01500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603320PMC
April 2014

Structure-function analysis of full-length midkine reveals novel residues important for heparin binding and zebrafish embryogenesis.

Biochem J 2013 May;451(3):407-15

Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore 117543.

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http://dx.doi.org/10.1042/BJ20121622DOI Listing
May 2013

17α-androstenediol-mediated oncophagy of tumor cells by different mechanisms is determined by the target tumor.

Ann N Y Acad Sci 2012 Jul;1262:127-33

Department of Microbiology and Immunology, Virginia Commonwealth University Medical Center, Richmond, Virginia, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2012.06602.xDOI Listing
July 2012

P2Y12 receptor expression is a critical determinant of functional responsiveness to ATX's MORFO domain.

Purinergic Signal 2012 Jun 4;8(2):181-90. Epub 2011 Dec 4.

Department of Anatomy, Virginia Commonwealth University Medical Center, Richmond, VA 23298, USA.

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http://dx.doi.org/10.1007/s11302-011-9283-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3350589PMC
June 2012

Requirements for generic antiepileptic medicines: a clinical perspective.

J Neurol 2011 Dec 11;258(12):2128-32. Epub 2011 Jun 11.

Department of Neurology at the Christian Doppler Klinik, Paracelsus Medical University, Salzburg, Ignaz Harrerstrasse 79, 5020, Salzburg, Austria.

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http://dx.doi.org/10.1007/s00415-011-6126-6DOI Listing
December 2011

Novel screening cascade identifies MKK4 as key kinase regulating Tau phosphorylation at Ser422.

Mol Cell Biochem 2011 Nov 3;357(1-2):199-207. Epub 2011 Jun 3.

CNS Discovery and Translation Pharma Research and Exploratory Development, F. Hoffmann-La Roche AG, Basel, Switzerland.

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http://dx.doi.org/10.1007/s11010-011-0890-6DOI Listing
November 2011

The neuro-steroid, 5-androstene 3β,17α diol; induces endoplasmic reticulum stress and autophagy through PERK/eIF2α signaling in malignant glioma cells and transformed fibroblasts.

Int J Biochem Cell Biol 2010 Dec 18;42(12):2019-29. Epub 2010 Sep 18.

Department of Neurosurgery, Virginia Commonwealth University, P.O. Box 980631, Richmond, VA 23298-0631, USA.

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http://dx.doi.org/10.1016/j.biocel.2010.09.003DOI Listing
December 2010

Tumor-infiltrating, myeloid-derived suppressor cells inhibit T cell activity by nitric oxide production in an intracranial rat glioma + vaccination model.

J Neuroimmunol 2010 Jun 8;223(1-2):20-30. Epub 2010 May 8.

Department of Neurosurgery, Virginia Commonwealth, Richmond, VA 23298-0631, USA.

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http://dx.doi.org/10.1016/j.jneuroim.2010.03.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883008PMC
June 2010

Effect of WT1 gene silencing on the tumorigenicity of human glioblastoma multiforme cells.

J Neurosurg 2010 Jan;112(1):18-25

Department of Anatomy and Neurobiology, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, Virginia 23298-0631, USA.

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http://dx.doi.org/10.3171/2008.11.JNS08368DOI Listing
January 2010

The anti-tumor effects of androstene steroids exhibit a strict structure-activity relationship dependent upon the orientation of the hydroxyl group on carbon-17.

Chem Biol Drug Des 2009 Dec 12;74(6):625-9. Epub 2009 Oct 12.

Department of Neurosurgery - Harold F. Young Neurosurgical Center and the Massey Cancer Center, Virginia Commonwealth University Medical Center, P.O. Box 980631, 1200 E. Broad Street, Richmond, VA 23298-0631, USA.

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http://dx.doi.org/10.1111/j.1747-0285.2009.00900.xDOI Listing
December 2009

Sorafenib and vorinostat kill colon cancer cells by CD95-dependent and -independent mechanisms.

Mol Pharmacol 2009 Aug 29;76(2):342-55. Epub 2009 May 29.

Department of Biochemistry and Molecular Biology, Massey Cancer Center, Virginia Commonwealth University, Richmond, VA 23298-0035, USA.

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http://dx.doi.org/10.1124/mol.109.056523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713126PMC
August 2009

Autophagy and the functional roles of Atg5 and beclin-1 in the anti-tumor effects of 3beta androstene 17alpha diol neuro-steroid on malignant glioma cells.

J Steroid Biochem Mol Biol 2009 Jul 16;115(3-5):137-45. Epub 2009 Apr 16.

Department of Neurosurgery - Harold F. Young Neurosurgical Center and Massey Cancer Center, Virginia Commonwealth University Medical Center, PO Box 980631, Richmond, VA 23298-0631, USA.

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http://dx.doi.org/10.1016/j.jsbmb.2009.03.013DOI Listing
July 2009

PERK-dependent regulation of MDA-7/IL-24-induced autophagy in primary human glioma cells.

Autophagy 2008 May 13;4(4):513-5. Epub 2008 Feb 13.

Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, Richmond, Virginia 23298-0035, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2674579PMC
http://dx.doi.org/10.4161/auto.5725DOI Listing
May 2008

PERK-dependent regulation of HSP70 expression and the regulation of autophagy.

Autophagy 2008 Apr 17;4(3):364-7. Epub 2008 Jan 17.

Department of Biochemistry and Molecular Biology, Virginia Commonwealth University, Richmond, Virginia, USA.

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http://dx.doi.org/10.4161/auto.5593DOI Listing
April 2008

Down-regulation of Wilms' tumor 1 expression in glioblastoma cells increases radiosensitivity independently of p53.

J Neurooncol 2007 Jun 6;83(2):163-72. Epub 2007 Jan 6.

Department of Neurosurgery, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA 23298-0631, USA.

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http://dx.doi.org/10.1007/s11060-006-9317-8DOI Listing
June 2007

Unusual temperature effects in propene polymerization using stereorigid zirconocene catalysts.

Chemphyschem 2005 Sep;6(9):1929-33

Department of Chemistry, University of Bergen, Allégaten 41, 5007 Bergen, Norway.

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http://dx.doi.org/10.1002/cphc.200400581DOI Listing
September 2005

Why are BINOL-based monophosphites such efficient ligands in Rh-catalyzed asymmetric olefin hydrogenation?

J Am Chem Soc 2005 Jul;127(29):10305-13

Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, D-45470 Mülheim/Ruhr, Germany.

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http://dx.doi.org/10.1021/ja052025+DOI Listing
July 2005

Predictors for negative attitudes toward subjects with epilepsy: a representative survey in the general public in Austria.

Epilepsia 2005 May;46(5):736-42

LBI for Epilepsy and Neuromuscular Disorders, Neurological Hospital Rosenhügel, Vienna, Austria.

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http://dx.doi.org/10.1111/j.1528-1167.2005.52404.xDOI Listing
May 2005

Tumor infiltration by myeloid suppressor cells in response to T cell activation in rat gliomas.

J Neurooncol 2005 May;73(1):29-36

Department of Neurosurgery, Virginia Commonwealth University Medical Center, Richmond, Virginia, 23298-0631, USA.

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http://dx.doi.org/10.1007/s11060-007-9442-zDOI Listing
May 2005

Thymic function and output of recent thymic emigrant T cells during intracranial glioma progression.

J Neurooncol 2003 Aug-Sep;64(1-2):45-54

Department of Anatomy and Surgery, Virginia Commonwealth University/Medical College of Virginia, Richmond, VA, USA.

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http://dx.doi.org/10.1007/bf02700019DOI Listing
December 2003

Contrasting effects of interleukin-2 secretion by rat glioma cells contingent upon anatomical location: accelerated tumorigenesis in the central nervous system and complete rejection in the periphery.

J Neuroimmunol 2003 Jul;140(1-2):49-60

Department of Anatomy and Neurobiology, Medical College of Virginia, Virginia Commonwealth University, P.O. Box 980709 MCV Station, Richmond, VA 23298-0709, USA.

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http://dx.doi.org/10.1016/s0165-5728(03)00167-xDOI Listing
July 2003

Irradiated tumor cell vaccine for treatment of an established glioma. I. Successful treatment with combined radiotherapy and cellular vaccination.

Cancer Immunol Immunother 2002 Jun 4;51(4):179-89. Epub 2002 Apr 4.

Department of Anatomy and Division of Neurosurgery, Virginia Commonwealth University/Medical College of Virginia, 1101 E. Marshall Street, P.O. Box 980709, Richmond, VA 23198-0709, USA.

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http://link.springer.com/10.1007/s00262-002-0269-3
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http://dx.doi.org/10.1007/s00262-002-0269-3DOI Listing
June 2002

Irradiated tumor cell vaccine for treatment of an established glioma. II. Expansion of myeloid suppressor cells that promote tumor progression.

Cancer Immunol Immunother 2002 Jun 6;51(4):190-9. Epub 2002 Apr 6.

Department of Anatomy, Virginia Commonwealth University/Medical College of Virginia, 1101 E. Marshall Street, P.O. Box 980709, MCV Station, Richmond, VA 23198-0709, USA.

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http://dx.doi.org/10.1007/s00262-002-0270-xDOI Listing
June 2002