Publications by authors named "Martin G Larson"

100Publications

An Early-Onset Subgroup of Type 2 Diabetes: A Multigenerational, Prospective Analysis in the Framingham Heart Study.

Diabetes Care 2020 Oct 8. Epub 2020 Oct 8.

Institute for Research on Healthy Aging and Department of Cardiology, Smidt Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA.

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http://dx.doi.org/10.2337/dc19-1758DOI Listing
October 2020

Metabolic Architecture of Acute Exercise Response in Middle-Aged Adults in the Community.

Circulation 2020 Sep 15. Epub 2020 Sep 15.

Cardiology Division and the Simches Cardiovascular Research Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA; Pulmonary Critical Care Unit, Massachusetts General Hospital, Boston, MA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.120.050281DOI Listing
September 2020

Metabolomic signatures of cardiac remodelling and heart failure risk in the community.

ESC Heart Fail 2020 Sep 10. Epub 2020 Sep 10.

NHBLI and Boston University's Framingham Heart Study, Framingham, MA, USA.

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http://dx.doi.org/10.1002/ehf2.12923DOI Listing
September 2020

Clinical course after a first episode of heart failure: insights from the Framingham Heart Study.

Eur J Heart Fail 2020 May 28. Epub 2020 May 28.

Framingham Heart Study, Framingham, MA, USA.

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http://dx.doi.org/10.1002/ejhf.1918DOI Listing
May 2020

Prognosis of "pre-heart failure" clinical phenotypes.

PLoS One 2020 10;15(4):e0231254. Epub 2020 Apr 10.

Framingham Heart Study, Framingham, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0231254PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147998PMC
July 2020

Lipidomic profiling identifies signatures of metabolic risk.

EBioMedicine 2020 Jan 24;51:102520. Epub 2019 Dec 24.

Framingham Heart Study, Framingham, MA, United States; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.10.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938899PMC
January 2020

Integrated Multiomics Approach to Identify Genetic Underpinnings of Heart Failure and Its Echocardiographic Precursors: Framingham Heart Study.

Circ Genom Precis Med 2019 12 8;12(12):e002489. Epub 2019 Nov 8.

Framingham Heart Study, MA (C.A., H.L., C.L., D.L., M.G.L., R.S.V.).

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http://dx.doi.org/10.1161/CIRCGEN.118.002489DOI Listing
December 2019

Prognostic Significance of Echocardiographic Measures of Cardiac Remodeling.

J Am Soc Echocardiogr 2020 01 14;33(1):72-81.e6. Epub 2019 Oct 14.

Boston University's and National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts; Sections of Preventive Medicine and Epidemiology and Cardiovascular Medicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.echo.2019.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986561PMC
January 2020

Sex Differences in Circulating Biomarkers of Cardiovascular Disease.

J Am Coll Cardiol 2019 09;74(12):1543-1553

Cardiology Division, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2019.06.077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756178PMC
September 2019

Familial Clustering of Cardiac Conduction Defects and Pacemaker Insertion.

Circ Arrhythm Electrophysiol 2019 07 20;12(7):e007150. Epub 2019 Jun 20.

National Heart, Lung, and Blood Institute's Framingham Heart Study, MA (B.M.K., C.A., M.S.D., M.G.L., R.S.V.).

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http://dx.doi.org/10.1161/CIRCEP.119.007150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588168PMC
July 2019

Objective physical activity and physical performance in middle-aged and older adults.

Exp Gerontol 2019 05 13;119:203-211. Epub 2019 Feb 13.

Framingham Heart Study, Framingham, MA, USA; Department of General Internal Medicine, Boston University School of Medicine, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.exger.2019.02.003DOI Listing
May 2019

Longitudinal Change in Galectin-3 and Incident Cardiovascular Outcomes.

J Am Coll Cardiol 2018 12;72(25):3246-3254

Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts; Cardiology Division, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2018.09.076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516745PMC
December 2018

Multisystem Trajectories Over the Adult Life Course and Relations to Cardiovascular Disease and Death.

J Gerontol A Biol Sci Med Sci 2019 10;74(11):1778-1785

National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, Massachusetts.

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http://dx.doi.org/10.1093/gerona/gly249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357457PMC
October 2019

Whole Blood Gene Expression Associated With Clinical Biological Age.

J Gerontol A Biol Sci Med Sci 2019 01;74(1):81-88

National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Massachusetts.

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http://dx.doi.org/10.1093/gerona/gly164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298179PMC
January 2019

Temporal Trends in the Incidence of and Mortality Associated With Heart Failure With Preserved and Reduced Ejection Fraction.

JACC Heart Fail 2018 08 11;6(8):678-685. Epub 2018 Jul 11.

Boston University's and National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts; Sections of Cardiology and Preventative Medicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jchf.2018.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076350PMC
August 2018

Protein Biomarkers of Cardiovascular Disease and Mortality in the Community.

J Am Heart Assoc 2018 07 13;7(14). Epub 2018 Jul 13.

National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA.

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http://dx.doi.org/10.1161/JAHA.117.008108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064847PMC
July 2018

Comorbidities and Cardiometabolic Disease: Relationship With Longitudinal Changes in Diastolic Function.

JACC Heart Fail 2018 04 7;6(4):317-325. Epub 2018 Mar 7.

Framingham Heart Study, Framingham, Massachusetts; Section of Preventive Medicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts; Cardiology Section, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jchf.2017.12.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878123PMC
April 2018

Familial clustering of hypertensive target organ damage in the community.

J Hypertens 2018 05;36(5):1086-1093

National Heart, Lung and Blood Institute's and Boston University's Framingham Heart Study.

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http://dx.doi.org/10.1097/HJH.0000000000001679DOI Listing
May 2018

Metabolic Predictors of Change in Vascular Function: Prospective Associations From a Community-Based Cohort.

Hypertension 2018 02 26;71(2):237-242. Epub 2017 Dec 26.

From the Section of Pediatric Cardiology, Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston (J.P.Z.); Department of Biostatistics (J.R., M.G.L.) and Department of Epidemiology (E.J.B., R.S.V.), School of Public Health, Sections of Preventive Medicine and Cardiovascular Medicine, Department of Medicine, School of Medicine (N.M.H., E.J.B., R.S.V.), Boston University's and National Heart, Blood and Lung Institute's Framingham Heart Study (J.R., M.G.L., E.J.B., R.S.V.), and Department of Mathematics (M.G.L.), Boston University, MA; and Cardiovascular Engineering Inc, Norwood, MA (G.F.M.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.10054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764805PMC
February 2018

Transcriptome-wide association study of inflammatory biologic age.

Aging (Albany NY) 2017 11;9(11):2288-2301

National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA 01702, USA.

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http://dx.doi.org/10.18632/aging.101321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723687PMC
November 2017

Prognosis of Prehypertension Without Progression to Hypertension.

Circulation 2017 09;136(13):1262-1264

From National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, MA (T.J.N., M.G.L., V.X., R.S.V., S.C.); Department of Biostatistics (M.G.L., V.X.), Department of Medicine, Section of Preventive Medicine (R.S.V.), Department of Medicine, Section of Cardiology (R.S.V.), and Department of Epidemiology (R.S.V.), Boston University School of Public Health, MA; and Department of Medicine, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (E.L.M., S.C.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.029317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658013PMC
September 2017

Epidemiology of Left Ventricular Systolic Dysfunction and Heart Failure in the Framingham Study: An Echocardiographic Study Over 3 Decades.

JACC Cardiovasc Imaging 2018 01 5;11(1):1-11. Epub 2017 Oct 5.

Boston University's and National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts; Departments of Medicine, Biostatistics and Epidemiology, Boston University Schools of Medicine and Public Health, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jcmg.2017.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756128PMC
January 2018

Association of amine biomarkers with incident dementia and Alzheimer's disease in the Framingham Study.

Alzheimers Dement 2017 Dec 8;13(12):1327-1336. Epub 2017 Jun 8.

Department of Neurology, Boston University School of Medicine, Boston, MA, USA; The Framingham Heart Study, Framingham, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722716PMC
December 2017

Prevalence, Correlates, and Prognosis of Healthy Vascular Aging in a Western Community-Dwelling Cohort: The Framingham Heart Study.

Hypertension 2017 08 30;70(2):267-274. Epub 2017 May 30.

From the National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, MA (T.J.N., A.L., M.G.L., E.J.B., R.S.V.); Department of Mathematics and Statistics, Boston University, MA (A.L., M.G.L.); Department of Biostatistics (M.G.L.), Evans Department of Medicine, Whitaker Cardiovascular Institute (N.M.H., E.J.B., R.S.V.), Section of Cardiology, Department of Medicine (N.M.H., E.J.B., R.S.V.), Section of Vascular Biology, Department of Medicine (N.M.H.), Section of Preventive Medicine, Department of Medicine (E.J.B., R.S.V.), and Department of Epidemiology (E.J.B., R.S.V.), Boston University School of Public Health, MA; and Cardiovascular Engineering, Inc, Norwood, MA (G.F.M.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509504PMC
August 2017

Heritability and risks associated with early onset hypertension: multigenerational, prospective analysis in the Framingham Heart Study.

BMJ 2017 May 12;357:j1949. Epub 2017 May 12.

National Heart, Blood and Lung Institute's and Boston University's Framingham Heart Study, Framingham, MA 01702, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430541PMC
http://dx.doi.org/10.1136/bmj.j1949DOI Listing
May 2017

Cardiometabolic Traits and Systolic Mechanics in the Community.

Circ Heart Fail 2017 May;10(5)

From the Cardiovascular Research Center and Cardiology Division, Department of Medicine, Massachusetts General Hospital, Boston (J.E.H.); National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA (J.E.H., E.L.M., M.G.L., D.L., C.T., E.J.B., R.S.V., S.C.); Cardiology Division, Department of Medicine, Vanderbilt University, Nashville, TN (T.J.W.); Department of Biostatistics (M.G.L.) and Department of Epidemiology (E.J.B., R.S.V.), Boston University School of Public Health, MA; Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, MA (C.T.); Division of Cardiology, Department of Medicine, Brigham and Women's Hospital, Boston, MA (J.A., S.C.); Division of Cardiology, Department of Medicine, Veterans Affairs Boston Healthcare System, MA (J.A.); Cardiovascular Engineering, Inc, Norwood, MA (G.F.M.); and Cardiovascular Medicine Section (E.J.B.), Section of Preventive Medicine and Epidemiology (E.J.B., R.S.V.), and Section of Cardiology (E.J.B., R.S.V.), Department of Medicine, Boston University School of Medicine, MA.

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.116.003536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500189PMC
May 2017

Risk for hypertension crosses generations in the community: a multi-generational cohort study.

Eur Heart J 2017 Aug;38(29):2300-2308

National Heart, Blood and Lung Institute's and Boston University's Framingham Heart Study, 73 Mt. Wayte Avenue, Suite 2, Framingham, MA 01702, USA.

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http://dx.doi.org/10.1093/eurheartj/ehx134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075041PMC
August 2017

Aortic-Brachial Arterial Stiffness Gradient and Cardiovascular Risk in the Community: The Framingham Heart Study.

Hypertension 2017 06 10;69(6):1022-1028. Epub 2017 Apr 10.

From the National Heart, Blood and Lung Institute's and Boston University's Framingham Heart Study, Framingham, MA (T.J.N., M.G.L., E.J.B., R.S.V.); Center for Clinical Translational Epidemiology and Comparative Effectiveness Research (B.K., R.S.V.), Section of Preventive Medicine, Department of Medicine (B.K., E.J.B., R.S.V.), Department of Biostatistics (M.G.L.), Evans Department of Medicine and Whitaker Cardiovascular Institute (N.M.H., E.J.B., R.S.V.), Section of Cardiology, Department of Medicine (N.M.H., E.J.B., R.S.V.), Section of Vascular Biology, Department of Medicine (N.M.H.), and Department of Epidemiology (E.J.B., R.S.V.), Boston University School of Public Health, MA; and Cardiovascular Engineering, Inc., Norwood, MA (G.F.M.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.116.08917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5426958PMC
June 2017

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function.

Authors:
Philipp S Wild Janine F Felix Arne Schillert Alexander Teumer Ming-Huei Chen Maarten J G Leening Uwe Völker Vera Großmann Jennifer A Brody Marguerite R Irvin Sanjiv J Shah Setia Pramana Wolfgang Lieb Reinhold Schmidt Alice V Stanton Dörthe Malzahn Albert Vernon Smith Johan Sundström Cosetta Minelli Daniela Ruggiero Leo-Pekka Lyytikäinen Daniel Tiller J Gustav Smith Claire Monnereau Marco R Di Tullio Solomon K Musani Alanna C Morrison Tune H Pers Michael Morley Marcus E Kleber Jayashri Aragam Emelia J Benjamin Joshua C Bis Egbert Bisping Ulrich Broeckel Susan Cheng Jaap W Deckers Fabiola Del Greco M Frank Edelmann Myriam Fornage Lude Franke Nele Friedrich Tamara B Harris Edith Hofer Albert Hofman Jie Huang Alun D Hughes Mika Kähönen Knhi Investigators Jochen Kruppa Karl J Lackner Lars Lannfelt Rafael Laskowski Lenore J Launer Margrét Leosdottir Honghuang Lin Cecilia M Lindgren Christina Loley Calum A MacRae Deborah Mascalzoni Jamil Mayet Daniel Medenwald Andrew P Morris Christian Müller Martina Müller-Nurasyid Stefania Nappo Peter M Nilsson Sebastian Nuding Teresa Nutile Annette Peters Arne Pfeufer Diana Pietzner Peter P Pramstaller Olli T Raitakari Kenneth M Rice Fernando Rivadeneira Jerome I Rotter Saku T Ruohonen Ralph L Sacco Tandaw E Samdarshi Helena Schmidt Andrew S P Sharp Denis C Shields Rossella Sorice Nona Sotoodehnia Bruno H Stricker Praveen Surendran Simon Thom Anna M Töglhofer André G Uitterlinden Rolf Wachter Henry Völzke Andreas Ziegler Thomas Münzel Winfried März Thomas P Cappola Joel N Hirschhorn Gary F Mitchell Nicholas L Smith Ervin R Fox Nicole D Dueker Vincent W V Jaddoe Olle Melander Martin Russ Terho Lehtimäki Marina Ciullo Andrew A Hicks Lars Lind Vilmundur Gudnason Burkert Pieske Anthony J Barron Robert Zweiker Heribert Schunkert Erik Ingelsson Kiang Liu Donna K Arnett Bruce M Psaty Stefan Blankenberg Martin G Larson Stephan B Felix Oscar H Franco Tanja Zeller Ramachandran S Vasan Marcus Dörr

J Clin Invest 2017 May 10;127(5):1798-1812. Epub 2017 Apr 10.

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https://www.jci.org/articles/view/84840
Publisher Site
http://dx.doi.org/10.1172/JCI84840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409098PMC
May 2017

Urinary metabolites along with common and rare genetic variations are associated with incident chronic kidney disease.

Kidney Int 2017 06 14;91(6):1426-1435. Epub 2017 Mar 14.

National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, USA; Division of Endocrinology and Metabolism, Brigham and Women's Hospital, Boston, Massachusetts, USA. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2017.01.007DOI Listing
June 2017

Stroke and Circulating Extracellular RNAs.

Stroke 2017 04 13;48(4):828-834. Epub 2017 Mar 13.

From the Department of Quantitative Health Sciences (E.M.) and Department of Medicine (K.T., J.E.F.), University of Massachusetts Medical School, Worcester; Department of Cardiology, Massachusetts General Hospital, Boston (R.S.); Department of Cardiology, University of Michigan, Ann Arbor (V.M.); Yale University Medical School, Computational Biology, New Haven, CT (M.G., J.R., R.K.); The NHLBI's and Boston University's Framingham Heart Study, MA (M.G.L.); Biostatistics Department, Boston University School of Public Health, MA (M.G.L.); and The Framingham Heart Study, Population Sciences Branch, NHLBI, Bethesda, MD (D.L.).

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http://dx.doi.org/10.1161/STROKEAHA.116.015140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373984PMC
April 2017

Relations of Arterial Stiffness With Postural Change in Mean Arterial Pressure in Middle-Aged Adults: The Framingham Heart Study.

Hypertension 2017 04;69(4):685-690

From the Cardiovascular Engineering, Inc, Norwood, MA (A.T., L.L.C., G.F.M.); Cardiovascular Research Center, Rhode Island Hospital, W. Alpert Medical School of Brown University, Providence (L.L.C.); National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA (J.R., M.G.L., D.L., E.J.B., R.S.V.); Department of Biostatistics, Boston University School of Public Health, MA (M.G.L.); Evans Department of Medicine (N.M.H., E.J.B., R.S.V.), Whitaker Cardiovascular Institute (N.M.H., E.J.B., R.S.V.), and Preventive Medicine and Cardiology Sections (E.J.B., R.S.V.), Boston University School of Medicine, MA; and National Heart, Lung, and Blood Institute, Bethesda, MD (D.L.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.116.08116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382873PMC
April 2017

Visualization, Quantification, and Alignment of Spectral Drift in Population Scale Untargeted Metabolomics Data.

Anal Chem 2017 02 26;89(3):1399-1404. Epub 2017 Jan 26.

Departments of Medicine and Pharmacology, University of California San Diego , La Jolla, California 92093, United States.

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http://dx.doi.org/10.1021/acs.analchem.6b04337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455767PMC
February 2017

Messenger RNA and MicroRNA transcriptomic signatures of cardiometabolic risk factors.

BMC Genomics 2017 02 8;18(1):139. Epub 2017 Feb 8.

National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, USA.

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http://dx.doi.org/10.1186/s12864-017-3533-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299677PMC
February 2017

Microvascular Function Contributes to the Relation Between Aortic Stiffness and Cardiovascular Events: The Framingham Heart Study.

Circ Cardiovasc Imaging 2016 Dec;9(12)

From the Cardiovascular Engineering, Inc., Norwood, MA (L.L.C., G.F.M.); Cardiovascular Research Center, Lifespan Cardiovascular Institute, W. Alpert Medical School of Brown University, Providence, RI (L.L.C.); Data Coordinating Center (J.N.P.), Department of Epidemiology (E.J.B., R.S.V.), and Department of Biostatistics (M.G.L.), Boston University School of Public Health, MA; Boston University and the National Heart, Lung, and Blood Institute's Framingham Study, MA (E.J.B., M.G.L., R.S.V.); and Cardiology and Preventive Medicine Sections, Department of Medicine (E.J.B., R.S.V.), Evans Department of Medicine (E.J.B., R.S.V., N.M.H.), and Whitaker Cardiovascular Institute (E.J.B., R.S.V., N.M.H.), Boston University School of Medicine, MA.

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https://www.ahajournals.org/doi/10.1161/CIRCIMAGING.116.0049
Publisher Site
http://dx.doi.org/10.1161/CIRCIMAGING.116.004979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557409PMC
December 2016

Reply.

J Hypertens 2016 12;34(12):2489-2490

aCardiovascular Engineering, Inc., Norwood bNHLBI's Framingham Study, Framingham, Massachusetts cPopulation Sciences Branch, National Heart, Lung, and Blood Institute, Bethesda, Maryland dDepartment of Mathematics and Statistics, Boston University eEvans Department of Medicine fWhitaker Cardiovascular Institute gSection of Preventive Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/HJH.0000000000001136DOI Listing
December 2016

Genetic Risk Prediction of Atrial Fibrillation.

Circulation 2017 Apr 28;135(14):1311-1320. Epub 2016 Oct 28.

From Cardiac Arrhythmia Service (S.A.L., P.T.E.), Cardiovascular Research Center (S.A.L., L.-C.W., S.K., P.T.E.), J. Philip Kistler Stroke Research Center, Department of Neurology (N.S.R., C.D.A., J.R.), and Center for Human Genetic Research (C.D.A., S.K., J.R.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge (S.A.L., C.D.A., L.-C.W., S.K., C.R., J.R., P.T.E.); Boston University and National Heart, Lung, and Blood Institute's Framingham Heart Study, MA (X.Y., M.G.L., K.L.L., E.J.B.); Department of Pediatrics (H.J.L., X.G., K.D.T., J.I.R.) and Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute (H.J.L., X.G., K.D.T., J.Y., J.I.R.), Harbor-UCLA Medical Center, Torrance, CA; Vanderbilt University, Nashville, TN (M.K., P.L.T., D.D.); Department of Cardiology, Clinical Sciences, Lund University, Sweden (J.G.S.); Skåne University Hospital, Lund, Sweden (J.G.S.); Departments of Cardiology (S.T., J.W.J.) and Gerontology and Geriatrics (S.T.), Leiden University Medical Center, the Netherlands; University of Groningen, University Medical Center Groningen, the Netherlands (M.R., B.G., N.V., J.E.S., P.v.d.H.); Department of Clinical Sciences, Lund University, Malmö, Sweden (P.A., G.E., O.M.); Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis (L.Y.C.); Robertson Center for Biostatistics (I.F.) and Institute of Cardiovascular and Medical Sciences (P.W.M., D.J.S.), University of Glasgow, UK; Department of Neurology, Rhode Island Hospital, Alpert Medical School of Brown University, Providence (K.L.F.); Department of Mathematics and Statistics, Boston University, Boston, MA (M.G.L.); Department of Biostatistics (M.G.L., K.L.L.), Department of Epidemiology (E.J.B.), Section of Cardiovascular Medicine, Department of Medicine (E.J.B.), and Preventive Medicine Section, Department of Medicine (E.J.B.), Boston University School of Public Health, MA; Cardiovascular Health Research Unit, Departments of Medicine (B.M.P., N.S., S.R.H.), Epidemiology (B.M.P., N.S., S.R.H.), and Health Services (B.M.P.), University of Washington, Seattle; Kaiser Permanente Health Research Institute, Kaiser Permanente, Seattle, WA (B.M.P., S.R.H.); Epidemiological Cardiology Research Center (EPICARE), Wake Forest School of Medicine, Winston-Salem, NC (E.Z.S.); Department of Medicine and Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN (D.R.); University of Illinois, Chicago (D.D.); Interuniversity Cardiology Institute of the Netherlands, Utrecht (J.W.J.); Department of Internal Medicine, Skåne University Hospital, Malmö, Sweden (O.M.); and Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (A.A.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380586PMC
April 2017

Cross-Sectional Associations of Flow Reversal, Vascular Function, and Arterial Stiffness in the Framingham Heart Study.

Arterioscler Thromb Vasc Biol 2016 12 27;36(12):2452-2459. Epub 2016 Oct 27.

From the Boston University's and the National Heart, Lung, and Blood Institute's Framingham Heart Study (M.G.L., R.S.V., E.J.B.), MA; Cardiology (R.S.V., E.J.B., J.A.V., N.M.H.) and Preventive Medicine Sections (R.S.V., E.J.B.), and Whitaker Cardiovascular Institute, School of Medicine (R.B.-R., R.S.V., E.J.B., J.A.V., N.M.H.), School of Public Health (N.W., J.P., M.G.L., R.S.V., E.J.B.), and Departments of Mathematics and Statistics (M.G.L.), Boston University, MA; and Cardiovascular Engineering Inc, Norwood, MA (G.F.M.).

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http://dx.doi.org/10.1161/ATVBAHA.116.307948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557404PMC
December 2016

Alcohol Consumption, Left Atrial Diameter, and Atrial Fibrillation.

J Am Heart Assoc 2016 09 14;5(9). Epub 2016 Sep 14.

Division of Cardiology, Department of Medicine, University of California at San Francisco, CA

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http://dx.doi.org/10.1161/JAHA.116.004060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079048PMC
September 2016

Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.

Nat Genet 2016 10 12;48(10):1162-70. Epub 2016 Sep 12.

Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320952PMC
October 2016

Trajectories of Risk Factors and Risk of New-Onset Atrial Fibrillation in the Framingham Heart Study.

Hypertension 2016 09 11;68(3):597-605. Epub 2016 Jul 11.

From the Department of Medicine, Boston University Medical Center, MA (F.R.); Department of Biostatistics (X.Y., M.G.L.) and Department of Epidemiology (R.S.V., E.J.B.), Boston University School of Public Health, MA; Section of Cardiovascular Medicine, Preventive Medicine and Epidemiology, Department of Medicine, Boston University School of Medicine, MA (X.Y., R.S.V., E.J.B.); Cardiovascular Research Center, Massachusetts General Hospital, Charlestown (P.T.E., S.A.L.); National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, MA (X.Y., M.G.L., R.S.V., E.J.B.); Department of Medicine, Cardiology Division, University of Massachusetts Medical School, Worcester (D.D.M.); Department of Medicine, Division of Cardiology, UPMC Heart & Vascular Institute, University of Pittsburgh, PA (J.W.M.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.116.07683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982514PMC
September 2016

A comparison of the CHARGE-AF and the CHA2DS2-VASc risk scores for prediction of atrial fibrillation in the Framingham Heart Study.

Am Heart J 2016 Aug 17;178:45-54. Epub 2016 May 17.

NHLBI and Boston University's Framingham Heart Study, Framingham, MA; Section of Cardiovascular Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA; Boston University School of Public Health, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.ahj.2016.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344697PMC
August 2016

Association of Parental Hypertension With Arterial Stiffness in Nonhypertensive Offspring: The Framingham Heart Study.

Hypertension 2016 09 25;68(3):584-9. Epub 2016 Jul 25.

From Boston University's and the National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA (C.A., M.G.L., D.L., E.J.B., R.S.V.); Section of Cardiology, Department of Internal Medicine, Glostrup Hospital, Denmark (C.A.); Cardiology Clinic of San Antonio, TX (R.Q.); Department of Epidemiology (D.E., E.J.B., R.S.V.) and Department of Biostatistics (M.G.L.), Boston University School of Public Health, MA; Department of Mathematics and Statistics, Boston University, MA (M.G.L.); Whitaker Cardiovascular Institute (N.M.H., J.A.V., E.J.B., R.S.V.) and Section of Preventive Medicine and Epidemiology (E.J.B., R.S.V.), Boston University School of Medicine, MA; National Heart, Lung and Blood Institute, Bethesda, MD (D.L.); and Cardiovascular Engineering, Inc, Norwood, MA (G.F.M.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.116.07426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002314PMC
September 2016

Relations of Arterial Stiffness and Brachial Flow-Mediated Dilation With New-Onset Atrial Fibrillation: The Framingham Heart Study.

Hypertension 2016 09 25;68(3):590-6. Epub 2016 Jul 25.

From the Department of Medicine, University of Massachusetts Medical School, Worcester (A.Y.S.); Data Coordinating Center (N.W.), Department of Biostatistics (X.Y., M.G.L.), Department of Epidemiology (R.S.V.), and Department of Epidemiology (E.J.B.), Boston University School of Public Health, MA; National Heart Lung and Blood Institute's and Boston University's Framingham Heart Study, MA (X.Y., M.G.L., R.S.V., E.J.B.); Section of Cardiovascular Medicine, Preventive Medicine and Epidemiology, Department of Medicine (R.S.V.) and Cardiology Division, Department of Medicine (N.M.H., J.W.M.), Boston University School of Medicine, MA; Cardiology Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School (P.T.E., S.A.L.); The Broad Institute of Harvard and MIT, Cambridge, MA (P.T.E., S.A.L.); Cardiovascular Engineering, Inc, Norwood, MA (G.F.M.); Evans Memorial Medicine Department, Cardiology Section, and Preventive Medicine Section, School of Medicine, Boston University, MA (E.J.B.); and Cardiology Division, Department of Medicine, University of Massachusetts Medical School, Worcester (D.D.M.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.116.07650DOI Listing
September 2016

Biomarkers for the prediction of venous thromboembolism in the community.

Thromb Res 2016 Sep 14;145:34-9. Epub 2016 Jul 14.

Framingham Heart Study of Boston University School of Medicine and NHLBI, Framingham, MA, USA; Section of Preventive Medicine and Epidemiology, Department of Medicine, Boston University School of Medicine, Boston, MA, USA; Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA; Section of Cardiology, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.thromres.2016.07.006DOI Listing
September 2016

Aptamer-Based Proteomic Profiling Reveals Novel Candidate Biomarkers and Pathways in Cardiovascular Disease.

Circulation 2016 Jul;134(4):270-85

From Division of Pulmonary and Critical Care Medicine, Department of Medicine (D.N.) and the Cardiovascular Research Center (D.N., S.S., D.S., M.J.K., X.S., M.D.B., J.F.O., L.A.F., R.E.G.), Massachusetts General Hospital, Harvard Medical School, Boston; Broad Institute of MIT and Harvard, Cambridge, MA (E.W.K., H.K., S.A.C., R.E.G.); Cardiovascular Division, Brigham and Women's Hospital, Boston, MA (M.D.B., M.S.S.); Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston (M.A.F., M.S.S., R.E.G.); Preventive Medicine Section, Department of Medicine, Boston University School of Medicine, MA (R.S.V.); Department of Biostatistics, Boston University School of Public Health, MA (M.G.L.); The National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA (M.G.L.); Division of Cardiovascular Medicine, Vanderbilt University, Nashville, TN (T.J.W.); and Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center, Boston, MA (R.E.G.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.021803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963294PMC
July 2016

Epidemiology of venous thromboembolism in the Framingham Heart Study.

Thromb Res 2016 Sep 29;145:27-33. Epub 2016 Jun 29.

Framingham Heart Study of Boston University School of Medicine and NHLBI, Framingham, MA, USA; NHLBI Division of Intramural Research, Bethesda, MD, USA; Cardiology Section, Department of Medicine, Boston Veteran's Administration Healthcare, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2016.06.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385100PMC
September 2016

Prevalence, Neurohormonal Correlates, and Prognosis of Heart Failure Stages in the Community.

JACC Heart Fail 2016 10 6;4(10):808-815. Epub 2016 Jul 6.

Framingham Heart Study, Framingham, Massachusetts; Section of Preventive Medicine & Epidemiology, Boston University School of Medicine, Boston, Massachusetts; Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jchf.2016.05.001DOI Listing
October 2016

Predicting Heart Failure With Preserved and Reduced Ejection Fraction: The International Collaboration on Heart Failure Subtypes.

Circ Heart Fail 2016 06;9(6)

From the Cardiovascular Research Center, Massachusetts General Hospital (J.E.H.); Cardiovascular Medicine Section, Department of Medicine (R.S.) and Section of Preventive Medicine and Epidemiology (R.S.V.), Boston University School of Medicine, MA; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, MA (J.E.H., R.S.V., D.L., M.G.L.); Department of Mathematics and Statistics, Boston University, MA (D.E., M.G.L.); Department of Cardiology (F.P.B., H.L.H., P.v.d.H., W.H.v.G., R.A.d.B.) and Division of Nephrology, Department of Internal Medicine (R.T.G.), University Medical Center Groningen, The Netherlands; Department of Medicine and Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY (J.R.K.); Division of Cardiology (S.J.S.), Department of Medicine (C.C., K.L.), and Department of Preventive Medicine (C.C., K.L.), Northwestern University Feinberg School of Medicine, Chicago, IL; Cardiovascular Health Research Unit, Department of Medicine, Department of Epidemiology, and Department of Health Services (B.M.P.) and Department of Biostatistics (T.M.B.), University of Washington; Group Health Research Institute, Group Health Cooperative, Seattle, WA (B.M.P.); Institute for Clinical Evaluative Sciences, Toronto, Canada (D.S.L.); University Health Network, University of Toronto, Canada (D.S.L.); Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins University, Baltimore, MD (M.J.B.); Department of Medicine, Hackensack University Medical Center and Rutgers New Jersey Medical School, Hackensack, NJ (J.M.G.); Center of Research on Psychology in Somatic Diseases, Department of Medical and Clinical Psychology, Tilburg University, Tilburg, The Netherlands (W.J.K.); Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Bethesda, MD (D.L.); and Department of Medicine, University of Maryland School of Medicine, Baltimore, MD (J.S.G.).

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.115.003116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902276PMC
June 2016