Martin Fassnacht

Martin Fassnacht

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Martin Fassnacht

Publications by authors named "Martin Fassnacht"

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Exquisite sensitivity of adrenocortical carcinomas to induction of ferroptosis.

Proc Natl Acad Sci U S A 2019 Oct 14. Epub 2019 Oct 14.

Division of Nephrology, Department of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, 01307 Dresden, Germany;

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http://dx.doi.org/10.1073/pnas.1912700116DOI Listing
October 2019

GLP-1 and PYY reduce high-fat food preference additively after Roux-en-Y gastric bypass in diet-induced obese rats.

Surg Obes Relat Dis 2019 Sep 16;15(9):1483-1492. Epub 2019 Apr 16.

Department of Experimental Surgery, University Hospital Würzburg, Würzburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.soard.2019.04.008DOI Listing
September 2019

Arginine-stimulated copeptin measurements in the differential diagnosis of diabetes insipidus: a prospective diagnostic study.

Lancet 2019 08 11;394(10198):587-595. Epub 2019 Jul 11.

Department of Endocrinology, Diabetology and Metabolism, University Hospital Basel, Basel, Switzerland; Department of Clinical Research, University of Basel and University Hospital Basel, Basel, Switzerland.

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http://dx.doi.org/10.1016/S0140-6736(19)31255-3DOI Listing
August 2019

Impact of USP8 Gene Mutations on Protein Deregulation in Cushing Disease.

J Clin Endocrinol Metab 2019 Jul;104(7):2535-2546

Division of Endocrinology and Diabetes, Department of Internal Medicine I, University Hospital, University of Wuerzburg, Wuerzburg, Germany.

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http://dx.doi.org/10.1210/jc.2018-02564DOI Listing
July 2019

A method for the minimally invasive drug monitoring of mitotane by means of volumetric absorptive microsampling for a home-based therapeutic drug monitoring.

Anal Bioanal Chem 2019 Jul 16;411(17):3951-3962. Epub 2019 May 16.

Institute for Pharmacy and Food Chemistry, University of Würzburg, Am Hubland, 97074, Würzburg, Germany.

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http://dx.doi.org/10.1007/s00216-019-01868-1DOI Listing
July 2019

The challenges of sodium measurements - indirect versus direct ion selective method.

Eur J Endocrinol 2019 Jun 1. Epub 2019 Jun 1.

M Christ-Crain, Endocrinology, Diabetology and Metabolism, Universitatsspital Basel, Basel, Switzerland.

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http://dx.doi.org/10.1530/EJE-19-0101DOI Listing
June 2019

Impact of 123 I-MIBG scintigraphy on clinical decision making in pheochromocytoma and paraganglioma.

J Clin Endocrinol Metab 2019 Mar 1. Epub 2019 Mar 1.

Department of Internal Medicine, sections of Endocrinology and Vascular Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1210/jc.2018-02355DOI Listing
March 2019

Adrenomedullary function, obesity and permissive influences of catecholamines on body mass in patients with chromaffin cell tumours.

Int J Obes (Lond) 2019 02 3;43(2):263-275. Epub 2018 Mar 3.

Department of Medicine III, Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.1038/s41366-018-0054-9DOI Listing
February 2019

Advanced Adrenocortical Carcinoma - What to do when First-Line Therapy Fails?

Exp Clin Endocrinol Diabetes 2019 Feb 23;127(2-03):109-116. Epub 2018 Nov 23.

Department of Internal Medicine I, Division of Endocrinology and Diabetes, University Hospital Würzburg, University of Würzburg, Germany.

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http://dx.doi.org/10.1055/a-0715-1946DOI Listing
February 2019

Plasma steroid metabolome profiling for the diagnosis of adrenocortical carcinoma.

Eur J Endocrinol 2019 Feb;180(2):117-125

Division of Endocrinology/Diabetology and Core Unit Clinical Mass Spectrometry, Department of Internal Medicine I, University Hospital Würzburg.

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http://dx.doi.org/10.1530/EJE-18-0782DOI Listing
February 2019

Alterations in Protein Kinase A Substrate Specificity as a Potential Cause of Cushing Syndrome.

Endocrinology 2019 Feb;160(2):447-459

Institute of Pharmacology and Toxicology and Bio-Imaging Center, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1210/en.2018-00775DOI Listing
February 2019

The Adrenal Gland: Central Relay in Health and Disease.

Exp Clin Endocrinol Diabetes 2019 Feb 27;127(2-03):81-83. Epub 2019 Feb 27.

Medizinische Klinik und Poliklinik IV, Klinikum der Universität, Ludwig-Maximilians-Universität München, Germany.

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0752-4176
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http://dx.doi.org/10.1055/a-0752-4176DOI Listing
February 2019

Hsp90 inhibition in adrenocortical carcinoma: Limited drug synergism with mitotane.

Mol Cell Endocrinol 2019 01 10;480:36-41. Epub 2018 Oct 10.

University Hospital Würzburg, Department of Internal Medicine I, Division of Endocrinology and Diabetes, Würzburg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03037207183029
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http://dx.doi.org/10.1016/j.mce.2018.10.009DOI Listing
January 2019

Adrenocortical incidentalomas and bone: from molecular insights to clinical perspectives.

Endocrine 2018 12 2;62(3):506-516. Epub 2018 Aug 2.

Department of Oncology and Metabolism, University of Sheffield Medical School, Sheffield, UK.

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http://dx.doi.org/10.1007/s12020-018-1696-zDOI Listing
December 2018

FGF-21 levels in polyuria-polydipsia syndrome.

Endocr Connect 2018 Dec;7(12):1501-1506

Departments of Endocrinology, Diabetology and Metabolism, University Hospital Basel, Basel, Switzerland.

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http://dx.doi.org/10.1530/EC-18-0469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311457PMC
December 2018

Impact of chronic hyponatremia on neurocognitive and neuromuscular function.

Eur J Clin Invest 2018 Nov 19;48(11):e13022. Epub 2018 Sep 19.

Integrated Research and Treatment Center for Adiposity Diseases, Leipzig University Medical Center, Leipzig, Germany.

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http://doi.wiley.com/10.1111/eci.13022
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http://dx.doi.org/10.1111/eci.13022DOI Listing
November 2018

Surviving ectopic Cushing's syndrome: quality of life, cardiovascular and metabolic outcomes in comparison to Cushing's disease during long-term follow-up.

Eur J Endocrinol 2018 Aug 6;179(2):109-116. Epub 2018 Jun 6.

Medizinische Klinik und Poliklinik IV, Klinikum der Ludwig-Maximilians-Universität München, München, Germany.

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http://dx.doi.org/10.1530/EJE-18-0212DOI Listing
August 2018

A Copeptin-Based Approach in the Diagnosis of Diabetes Insipidus.

N Engl J Med 2018 Aug;379(5):428-439

From the University of Leipzig, Department of Endocrinology and Nephrology (W.F., A.T.), and Leipzig University Medical Center, Integrated Research and Treatment Center Adiposity Diseases (W.F.), Leipzig, the Department of Internal Medicine I, Division of Endocrinology and Diabetes, University Hospital, University of Würzburg (I.C., M.K., M.F.), and the Clinical Trial Center (U.M.) and Central Laboratory (M.F.), University Hospital Würzburg, Würzburg, Medizinische Klinik und Poliklinik IV, Ludwig-Maximilians-Universität, Munich (J.S.), the Department of Neurosurgery, University Hospital Hamburg-Eppendorf, Hamburg (J.F.), and Experimental and Clinical Endocrinology, University Hospital Lübeck, Lübeck (G.B.) - all in Germany; the Clinic of Endocrinology, Diabetology and Metabolism (J.R., I.S., B.W., E.C., M.C.-C.) and the Clinical Trial Unit (D.R.V.), Department of Clinical Research, University of Basel and University Hospital Basel, Basel, the Department of Endocrinology, Kantonsspital St. Gallen, St. Gallen (T.D., S.B.), the Department of Endocrinology, Inselspital Bern, Bern (E.C.), the Department of Endocrinology, Luzerner Kantonsspital, Lucerne (C.H., S.F.), and the Division of Endocrinology, Diabetology and Metabolism, Medical University Clinic, Kantonsspital Aarau, Aarau (B.M.) - all in Switzerland; and Faculdade de Medicina da UFMG, Universidade Federal de Minas Gerais (J.D., A.R.-O.), and Hermes Pardini Institute (J.D.), Belo Horizonte, Brazil.

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http://dx.doi.org/10.1056/NEJMoa1803760DOI Listing
August 2018

Radiation Exposure of Adrenal Vein Sampling - a German Multicenter Study.

Eur J Endocrinol 2018 Aug 1. Epub 2018 Aug 1.

S Hahner, Department of Medicine I, Division of Endocrinology and Diabetology, University Hospital, University of Würzburg, Würzburg, Germany.

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https://eje.bioscientifica.com/view/journals/eje/179/4/EJE-1
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http://dx.doi.org/10.1530/EJE-18-0328DOI Listing
August 2018

Mitotane Monotherapy in Patients With Advanced Adrenocortical Carcinoma.

J Clin Endocrinol Metab 2018 04;103(4):1686-1695

Department of Internal Medicine I, Division of Endocrinology and Diabetes, University Hospital Würzburg, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1210/jc.2017-02591DOI Listing
April 2018

High-Resolution Tissue Mass Spectrometry Imaging Reveals a Refined Functional Anatomy of the Human Adult Adrenal Gland.

Endocrinology 2018 03;159(3):1511-1524

Department of Internal Medicine, Division of Endocrinology and Diabetology, University Hospital Würzburg, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1210/en.2018-00064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839739PMC
March 2018

ERCC1 as predictive biomarker to platinum-based chemotherapy in adrenocortical carcinomas.

Eur J Endocrinol 2018 Feb 29;178(2):181-188. Epub 2017 Nov 29.

Division of Endocrinology and Diabetes, Department of Internal Medicine I, University Hospital, University of Wuerzburg, Wuerzburg, Germany.

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http://dx.doi.org/10.1530/EJE-17-0788DOI Listing
February 2018

Release and Decay Kinetics of Copeptin vs AVP in Response to Osmotic Alterations in Healthy Volunteers.

J Clin Endocrinol Metab 2018 02;103(2):505-513

Department of Endocrinology, Diabetology, and Metabolism, University Hospital of Basel, Basel, Switzerland.

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http://dx.doi.org/10.1210/jc.2017-01891DOI Listing
February 2018

Targeting CXCR4 (CXC Chemokine Receptor Type 4) for Molecular Imaging of Aldosterone-Producing Adenoma.

Hypertension 2018 02 26;71(2):317-325. Epub 2017 Dec 26.

From the Department of Internal Medicine I, Endocrinology and Diabetes Unit (B.H., C.T.F., M.F., K.L., S.H.), Department of Nuclear Medicine (A.S., K.H., A.K.B., C.B.), and Comprehensive Cancer Center Wuerzburg (T.D., M.F.), University Hospital of Wuerzburg, University of Wuerzburg, Germany; Division of Internal Medicine and Hypertension, Department of Medical Sciences, University of Torino, Italy (P.M., T.A.W., S.M.); Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Germany (F.B., M.R., T.A.W., Y.R.); Department of Nuclear Medicine, Klinikum rechts der Isar der Technischen Universität München, Germany (M.M.); Endocrinology in Charlottenburg, Berlin, Germany (M.Q.); Department of General, Visceral, and Transplant Surgery, Campus Virchow Klinikum, Charité-Universitätsmedizin Berlin, Germany (N.R.); Department of Pathology, University of Würzburg, Germany (V.W.); Division of Endocrinology, G.V. (Sonny) Montgomery VA Medical Center, MS (C.E.G.-S.); Institute of Pathology, University Hospital Essen, University of Duisburg-Essen, Germany (A.-C.R.); ENDOC, Center for Endocrine Tumors, Hamburg, Germany (S.P.); Pharmaceutical Radiochemistry, Technische Universität München, Garching bei München, Germany (H.-J.W.); and Scintomics GmbH, Fürstenfeldbruck, Germany (S.K.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09975DOI Listing
February 2018

Antwort.

Dtsch Med Wochenschr 2018 02 6;143(3):200. Epub 2018 Feb 6.

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http://dx.doi.org/10.1055/s-0044-100145DOI Listing
February 2018

Steroid Profiling for Adrenocortical Disorders: A Pathway for Omics-Based Diagnostics.

Clin Chem 2017 12 10;63(12):1787-1789. Epub 2017 Oct 10.

Department of Internal Medicine and Central Laboratory, University Hospital of Würzburg, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1373/clinchem.2017.281048DOI Listing
December 2017

[Pheochromocytoma - Current Recommendations on Diagnostics, Therapy and Follow-up].

Dtsch Med Wochenschr 2017 12 5;142(24):1797-1800. Epub 2017 Dec 5.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-112777
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http://dx.doi.org/10.1055/s-0043-112777DOI Listing
December 2017

Cortisol-related metabolic alterations assessed by mass spectrometry assay in patients with Cushing's syndrome.

Eur J Endocrinol 2017 Aug 31;177(2):227-237. Epub 2017 May 31.

Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, München, Germany.

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http://dx.doi.org/10.1530/EJE-17-0109DOI Listing
August 2017

Outcome after resection of Adrenocortical Carcinoma liver metastases: a retrospective study.

BMC Cancer 2017 Aug 4;17(1):522. Epub 2017 Aug 4.

Department of General, Visceral, Vascular and Pediatric Surgery, University Hospital, University of Wuerzburg, Wuerzburg, Germany.

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http://dx.doi.org/10.1186/s12885-017-3506-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545028PMC
August 2017

Topoisomerase 2α and thymidylate synthase expression in adrenocortical cancer.

Endocr Relat Cancer 2017 07 21;24(7):319-327. Epub 2017 Apr 21.

Department of OncologyUniversity of Turin, Pathology Unit, City of Health and Science Hospital, Turin, Italy.

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http://dx.doi.org/10.1530/ERC-17-0095DOI Listing
July 2017

[Adrenal incidentaloma - what to do and what not?]

Authors:
Martin Fassnacht

Dtsch Med Wochenschr 2017 Feb 10;142(3):158-161. Epub 2017 Feb 10.

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http://dx.doi.org/10.1055/s-0042-121731DOI Listing
February 2017

Investigating the Chemokine Receptor 4 as Potential Theranostic Target in Adrenocortical Cancer Patients.

Clin Nucl Med 2017 Jan;42(1):e29-e34

From the *Department of Nuclear Medicine, †Division of Endocrinology, Department of Internal Medicine I, ‡Comprehensive Cancer Center, and §Department of Radiology, University Hospital of Würzburg, Würzburg; ∥Pharmaceutical Radiochemistry, Technische Universität München, Munich; ¶Scintomics GmbH, Fürstenfeldbruck, Germany; and **Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, CA.

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http://dx.doi.org/10.1097/RLU.0000000000001435DOI Listing
January 2017

Drug Synergism of Proteasome Inhibitors and Mitotane by Complementary Activation of ER Stress in Adrenocortical Carcinoma Cells.

Horm Cancer 2016 12 8;7(5-6):345-355. Epub 2016 Sep 8.

Comprehensive Cancer Center Mainfranken, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1007/s12672-016-0273-2DOI Listing
December 2016

Clinical presentation, treatment and outcome of anaplastic thyroid carcinoma: results of a multicenter study in Germany.

Eur J Endocrinol 2016 Dec;175(6):521-529

Department of Endocrinology and MetabolismUniversity Hospital Essen, University Duisburg-Essen, Essen, Germany

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http://dx.doi.org/10.1530/EJE-16-0574DOI Listing
December 2016

Preclinical progress and first translational steps for a liposomal chemotherapy protocol against adrenocortical carcinoma.

Endocr Relat Cancer 2016 10 22;23(10):825-37. Epub 2016 Aug 22.

Endocrine Research UnitMedizinische Klinik und Poliklinik IV, Ludwig-Maximilians-University, Munich, Germany

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http://dx.doi.org/10.1530/ERC-16-0249DOI Listing
October 2016

Genetic Landscape of Sporadic Unilateral Adrenocortical Adenomas Without PRKACA p.Leu206Arg Mutation.

J Clin Endocrinol Metab 2016 09 7;101(9):3526-38. Epub 2016 Jul 7.

Department of Internal Medicine I (C.L.R., I.W., M.F.), Division of Endocrinology and Diabetes, University Hospital, University of Wuerzburg, 97080 Wuerzburg, Germany; Medizinische Klinik und Poliklinik IV (G.D.D., M.R., F.B.), Klinikum der Universitaet Muenchen, 80337 Munich, Germany; Comprehensive Cancer Center Mainfranken (S.S., S.A., M.F.), University of Wuerzburg, 97080 Wuerzburg, Germany; Institut Cochin, Inserm U1016 (S.F., G.A., J.B.), CNRS UMR8104, Descartes University, 75006 Paris, France; Department of Endocrinology (S.F., G.A., J.B.), Reference Center for Rare Adrenal Diseases, Hôpital Cochin, 75014 Paris, France; Institute of Pharmacology and Toxicology and Bio-Imaging Center/Rudolf Virchow Center (D.C.), University of Wuerzburg, 97080 Wuerzburg, Germany; Institute of Human Genetics (T.S., T.M.S.), Helmholtz Zentrum Munich, 85764 Neuherberg, Germany; Core Unit System Medicine University of Wuerzburg (S.A.), 97080 Wuerzburg, Germany; Endocrinology Unit (B.R., C.S., F.M.), University Hospital of Padua, 35122 Padua, Italy; Department of Visceral, Thoracic, and Vascular Surgery (J.W., D.K.B.), University Hospital Giessen and Marburg, 35043 Marburg, Germany; Endocrinology Unit (M.M.), Department of Experimental and Clinical Biomedical Sciences, University of Florence, 50121 Florence, Italy; Department of Endocrinology (D.K.), University Hospital Centre Zagreb, 10000 Zagreb, Croatia; Unit of Endocrinology and Metabolic Diseases (I.C.), Fondazione IRCCS Cá Granda-Ospedale Maggiore Policlinico, 20122 Milan, Italy; Institute of Human Genetics (T.M.S.), Technische Universität Munich, 80333 Munich, Germany; and Central Laboratory (M.F.), Research Unit, University Hospital Wuerzburg, 97080 Wuerzburg, Germany.

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http://dx.doi.org/10.1210/jc.2016-1586DOI Listing
September 2016

FATE1 antagonizes calcium- and drug-induced apoptosis by uncoupling ER and mitochondria.

EMBO Rep 2016 09 11;17(9):1264-80. Epub 2016 Jul 11.

Institut de Pharmacologie Moléculaire et Cellulaire CNRS UMR 7275 Sophia Antipolis, Valbonne, France NEOGENEX CNRS International Associated Laboratory, Valbonne, France University of Nice - Sophia Antipolis, Valbonne, France

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http://dx.doi.org/10.15252/embr.201541504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007562PMC
September 2016

MANAGEMENT OF ENDOCRINE DISEASE: Imaging for the diagnosis of malignancy in incidentally discovered adrenal masses: a systematic review and meta-analysis.

Eur J Endocrinol 2016 Aug 2;175(2):R51-64. Epub 2016 Jun 2.

Institute of Metabolism and Systems ResearchUniversity of Birmingham, Birmingham, UK Centre for EndocrinologyDiabetes and Metabolism, Birmingham Health Partners, Birmingham, UK

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http://dx.doi.org/10.1530/EJE-16-0461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065077PMC
August 2016

DIAGNOSIS OF ENDOCRINE DISEASE: The diagnostic performance of adrenal biopsy: a systematic review and meta-analysis.

Eur J Endocrinol 2016 Aug 2;175(2):R65-80. Epub 2016 Jun 2.

Evidence-Based Practice CenterCenter for the Science of Healthcare Delivery, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1530/EJE-16-0297DOI Listing
August 2016

Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors.

Eur J Endocrinol 2016 Aug;175(2):G1-G34

Departments of Clinical Epidemiology and Internal MedicineLeiden University Medical Centre, Leiden, The Netherlands Department of Clinical EpidemiologyAarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1530/EJE-16-0467DOI Listing
August 2016

Salvage Treatment of Adrenocortical Carcinoma with Trofosfamide.

Horm Cancer 2016 06 9;7(3):211-8. Epub 2016 Mar 9.

Comprehensive Cancer Center Mainfranken, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1007/s12672-016-0260-7DOI Listing
June 2016

Expression of 11beta-hydroxysteroid-dehydrogenase type 2 in human thymus.

Steroids 2016 06 26;110:35-40. Epub 2016 Mar 26.

Department of Pediatrics, University Hospital Wuerzburg, Josef-Schneider-Str. 2, 97080 Wuerzburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.steroids.2016.03.019DOI Listing
June 2016

[Adrenocortical carcinoma and pregnancy].

Ann Endocrinol (Paris) 2016 Jun 9;77(2):139-47. Epub 2016 May 9.

Department of Endocrinology, Cochin University Hospital, AP-HP, French Adrenal Cancer Network COMETE-Cancer, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France; UMR 8104, institut Cochin, Paris, France.

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http://dx.doi.org/10.1016/j.ando.2016.04.024DOI Listing
June 2016

Dyslipidemia causes overestimation of plasma mitotane measurements.

Endocrinol Diabetes Metab Case Rep 2016 10;2016:150135. Epub 2016 Jun 10.

INSERM U1185, Fac Med Paris Sud, Le Kremlin-Bicêtre, France; Nuclear Medicine and Endocrine Oncology Department, Gustave Roussy, Villejuif, France.

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http://dx.doi.org/10.1530/EDM-15-0135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4901334PMC
June 2016

Inhibition of Cholesterol Esterification in the Adrenal Gland by ATR101/PD132301-2, A Promising Case of Drug Repurposing.

Endocrinology 2016 05;157(5):1719-21

Division of Endocrinology and Diabetology, Department of Internal Medicine, University Hospital Würzburg, University of Würzburg; and Clinical Chemistry and Laboratory Medicine, University Hospital Würzburg; and Comprehensive Cancer Center Mainfranken, University of Würzburg, 97080 Würzburg, Germany.

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http://dx.doi.org/10.1210/en.2016-1210DOI Listing
May 2016

Association of mitotane with chylomicrons and serum lipoproteins: practical implications for treatment of adrenocortical carcinoma.

Eur J Endocrinol 2016 Mar 15;174(3):343-53. Epub 2015 Dec 15.

Endocrine and Diabetes UnitDepartment of Internal Medicine IInfectiology UnitDepartment of Internal Medicine II, University Hospital Würzburg, Oberdürrbacher Street 6, 97080 Würzburg, GermanyComprehensive Cancer Center MainfrankenUniversity of Würzburg, Würzburg, GermanyDivision of Laboratory MedicineMedical Care Centre of Human Genetics Ulm, Ulm, GermanyDepartment of Nuclear MedicineUniversity Hospital Würzburg, Würzburg, GermanyClinical Chemistry and Laboratory MedicineUniversity Hospital Würzburg, Würzburg, Germany.

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http://www.eje-online.org/content/early/2015/12/15/EJE-15-09
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http://www.eje-online.org/lookup/doi/10.1530/EJE-15-0946
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http://dx.doi.org/10.1530/EJE-15-0946DOI Listing
March 2016

Landscape of somatic mutations in sporadic GH-secreting pituitary adenomas.

Eur J Endocrinol 2016 Mar 23;174(3):363-72. Epub 2015 Dec 23.

Department of Internal Medicine IEndocrine and Diabetes Unit, University Hospital, University of Wuerzburg, Oberduerrbacherstrasse 6, 97080 Wuerzburg, GermanyEndocrinology and Diabetology UnitDepartment of Clinical Sciences and Community Health, University of Milan, Milan, ItalyCentral LaboratoryUniversity Hospital, University of Wuerzburg, Wuerzburg, GermanyInstitute of Human GeneticsHelmholtz Zentrum Munich, Neuherberg, GermanyComprehensive Cancer Center MainfrankenUniversity of Wuerzburg, Wuerzburg, GermanyMedizinische Klinik and Poliklinik IVLudwig-Maximilians University, Munich, GermanyCore Unit Systems MedicineUniversity of Wuerzburg, Wuerzburg, GermanyEndocrinology UnitDepartment of Biomedical Sciences, Humanitas Research Hospital, Humanitas University, Rozzano, Milan, ItalyInstitute of Pharmacology and Toxicology and Bioimaging CenterUniversity of Wuerzburg, Wuerzburg, GermanyDepartment of NeurosurgeryUniversity Hospital of Erlangen, Erlangen, GermanyNeurosurgeryUniversity Hospital of Hamburg-Eppendorf, Hamburg, GermanyInstitute of Human GeneticsTechnische Universitaet Muenchen, Munich, Germany Department of Internal Medicine IEndocrine and Diabetes Unit, University Hospital, University of Wuerzburg, Oberduerrbacherstrasse 6, 97080 Wuerzburg, GermanyEndocrinology and Diabetology UnitDepartment of Clinical Sciences and Community Health, University of Milan, Milan, ItalyCentral LaboratoryUniversity Hospital, University of Wuerzburg, Wuerzburg, GermanyInstitute of Human GeneticsHelmholtz Zentrum Munich, Neuherberg, GermanyComprehensive Cancer Center MainfrankenUniversity of Wuerzburg, Wuerzburg, GermanyMedizinische Klinik and Poliklinik IVLudwig-Maximilians University, Munich, GermanyCore Unit Systems MedicineUniversity of Wuerzburg, Wuerzburg, GermanyEndocrinology UnitDepartment of Biomedical Sciences, Humanitas Research Hospital, Humanitas University, Rozzano, Milan, ItalyInstitute of Pharmacology and Toxicology and Bioimaging CenterUniversity of Wuerzburg, W

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http://dx.doi.org/10.1530/EJE-15-1064DOI Listing
March 2016

[Hormone therapy through changing times].

Dtsch Med Wochenschr 2016 Feb 3;141(3):161-4. Epub 2016 Feb 3.

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http://dx.doi.org/10.1055/s-0041-109320DOI Listing
February 2016

High evening salivary cortisol is an independent predictor of increased mortality risk in patients with systolic heart failure.

Int J Cardiol 2016 Jan 20;203:69-73. Epub 2015 Oct 20.

Comprehensive Heart Failure Center, University of Würzburg, Würzburg, Germany; Department of Internal Medicine I, Endocrine and Diabetes Unit, University Hospital Würzburg, Würzburg, Germany; Central Laboratory, Research Unit, University Hospital Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1016/j.ijcard.2015.10.084DOI Listing
January 2016

Safety and tolerability of sorafenib in patients with radioiodine-refractory thyroid cancer.

Endocr Relat Cancer 2015 12;22(6):877-87

Division of Hematology/OncologyUniversity of Michigan Comprehensive Cancer Center, University of Michigan Health System, 1500 E. Medical Center Drive, Ann Arbor, Michigan 48109, USAEndocrine UnitDepartment of Medicine I, University Hospital, University of Würzburg, Würzburg, GermanyComprehensive Cancer Center MainfrankenUniversity of Würzburg, Würzburg, GermanyDepartment of Medical OncologyCancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaBeijing Key Laboratory of Clinical Study on Anticancer Molecular Targeted DrugsBeijing, ChinaRadiotherapy DepartmentMedical University, Sofia, BulgariaInstitut BergonieBordeaux, FranceTianjin Medical University Cancer HospitalTianjin, ChinaFondazione IRCCS Ca' GrandaMilan, ItalyDepartment of Pathophysiology and TransplantationUniversity of Milan, Milan, ItalyNagoya University HospitalNagoya, JapanAichi Cancer Center HospitalNagoya, JapanSeoul National University College of MedicineSeoul, KoreaAsan Medicine CenterSeoul, KoreaDepartment of Internal MedicineRadboud University Nijmegen Medical Center, Nijmegen, The NetherlandsBayer HealthCare PharmaceuticalsMontville, New Jersey, USABayer Pharma AGBerlin, GermanyInstitut Gustave RoussyVillejuif, FranceDepartment of Otorhinolaryngology: Head and Neck SurgeryAbramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1530/ERC-15-0252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570090PMC
December 2015

Pregnancy in Women Previously Treated for an Adrenocortical Carcinoma.

J Clin Endocrinol Metab 2015 Dec 13;100(12):4604-11. Epub 2015 Oct 13.

Department of Endocrinology (P.d.C., L.C., M.-L.R.S.), Ambroise Paré University Hospital, Assistance Publique Hôpitaux de Paris (AP-HP), 92100 Boulogne Billancourt, France; Medizinische Klinik IV (K.R., M.F.), Klinikum der Universität München, München 80336, Germany; Inserm U1173 (L.C., M.-L.R.-S.), Université de Versailles St-Quentin-en-Yvelines, 78280 Montigny-le-Bretonneux, France; Unité de Recherche Clinique (J.R.), Hospitalo Universitaire Paris Île-de-France Ouest, AP-HP, Hôpital Ambroise Paré, 92100 Boulogne, France; Funktionsbereich Spezielle Endokrinologie (M.S.), Universitätsklinikum Düsseldorf, 40225 Düsseldorf, Germany; Department of Endocrinology (R.L., J.B., X.B.), Cochin University Hospital, AP-HP, French Adrenal Cancer Network COrtico MEdullo-surrénale Tumeur Endocrines (COMETE)-Cancer and Unite Mixte de Recherche 8104, Institut Cochin, 75014 Paris, France; Comprehensive Cancer Center Mainfranken (A.-C.K., M.F.), University of Würzburg, Würzburg, 97080 Germany; Institut Gustave Roussy (S.L.), 94800 Villejuif, France; Department of Medicine I (T.D., M.F.), Endocrine Unit, University Hospital, University of Würzburg, Würzburg, 97080 Germany; Centre Hospitalier Régional Universitaire de Lille (C.D.C.), Lille, 59000 France; Endocrinology and Diabetes Unit (S.H), Department of Medicine I, University Hospital, University of Würzburg, 97080 Würzburg, Germany; Department of Endocrinology (D.D.), Nantes University Hospital, 44000 Nantes, France; Department of Endocrinology and Nephrology (K.M.), University of Leipzig, 04357 Leipzig, Germany; Service d'Endocrinologie Maladies Métaboliques et Nutrition (P.C.), Pôle Cardio-Vasculaire et Métabolique, Centre Hospitalier Universitaire Larrey, 10623 Toulouse, France; Division of Endocrinology and Diabetology (J.W.), University Hospital Giessen and Marburg, Campus Marburg, 35041 Marburg, Germany; Department of Endocrinology (O.C.), Michallon Teaching Hospital, 38043 Grenoble, France; Endocrinol

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http://dx.doi.org/10.1210/jc.2015-2341DOI Listing
December 2015

Mitotane Inhibits Sterol-O-Acyl Transferase 1 Triggering Lipid-Mediated Endoplasmic Reticulum Stress and Apoptosis in Adrenocortical Carcinoma Cells.

Endocrinology 2015 Nov 25;156(11):3895-908. Epub 2015 Aug 25.

Department of Internal Medicine I, Endocrinology and Diabetes Unit (S.S., I.S., E.C., F.G., A.G., I.W., M.B., C.L.R., T.D., B.A., M.F.), University Hospital Würzburg, 97080 Würzburg, Germany; Comprehensive Cancer Center Mainfranken (S.S., A.R., M.F., M.K.), 97080 Würzburg, Germany; Institute of Pathology (E.L., A.R.), University of Würzburg, 97080 Würzburg, Germany; Institute of Clinical Chemistry and Laboratory Medicine (S.M., G.L., G.S.), University Hospital Regensburg, 93053 Regensburg, Germany; Department of Nuclear Medicine (A.S.), University Hospital Würzburg, 97080 Würzburg, Germany; and Clinical Chemistry and Laboratory Medicine (S.K., M.F.), University Hospital Würzburg, 97080 Würzburg, Germany.

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http://dx.doi.org/10.1210/en.2015-1367DOI Listing
November 2015

Decoding the genetic basis of Cushing's disease: USP8 in the spotlight.

Eur J Endocrinol 2015 Oct 26;173(4):M73-83. Epub 2015 May 26.

Department of EndocrinologyMax Planck Institute of Psychiatry, Kraepelinstrasse 10, Munich 80804, GermanyMedizinische Klinik und Poliklinik IVLudwig-Maximilians-Universität München, Munich, GermanyEndocrine and Diabetes UnitDepartment of Medicine I, University Hospital, University of Würzburg, Würzburg, GermanyDepartment of Biological SciencesTokyo Institute of Technology, 4259-B16 Nagatsuta, Midori, Yokohama 226-8501, Japan

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http://dx.doi.org/10.1530/EJE-15-0320DOI Listing
October 2015

The New Molecular Landscape of Cushing's Disease.

Trends Endocrinol Metab 2015 Oct;26(10):573-583

Department of Internal Medicine I, Endocrine and Diabetes Unit, University Hospital Würzburg, University of Würzburg, Würzburg, Germany.

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http://www.cell.com/trends/endocrinology-metabolism/pdf/S104
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http://dx.doi.org/10.1016/j.tem.2015.08.003DOI Listing
October 2015

Notch1 pathway in adrenocortical carcinomas: correlations with clinical outcome.

Endocr Relat Cancer 2015 Aug 15;22(4):531-43. Epub 2015 May 15.

Endocrine and Diabetes UnitDepartment of Internal Medicine I, University Hospital, University of Wuerzburg, Oberrduerrbacher-Strasse 6, 97080 Wuerzburg, GermanyCentral LaboratoryUniversity Hospital of Wuerzburg, Wuerzburg, GermanyInstitute of PathologyUniversity of Wuerzburg, Wuerzburg, GermanyComprehensive Cancer Center MainfrankenWuerzburg, Germany.

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http://dx.doi.org/10.1530/ERC-15-0163DOI Listing
August 2015

A case report of a solitary pancreatic metastasis of an adrenocortical carcinoma.

BMC Surg 2015 Jul 31;15:93. Epub 2015 Jul 31.

Department of General, Visceral, Vascular and Pediatric Surgery, University Hospital Wuerzburg, Wuerzburg, Germany.

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http://dx.doi.org/10.1186/s12893-015-0076-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520015PMC
July 2015

[Endogenous Cushing's syndrome: new insights].

Dtsch Med Wochenschr 2015 Jun 12;140(12):874-7. Epub 2015 Jun 12.

Universitätsklinikum Würzburg, Medizinische Klinik und Poliklinik I, Schwerpunkt Endokrinologie und Diabetologie, Würzburg.

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http://dx.doi.org/10.1055/s-0041-102588DOI Listing
June 2015

The Treatment of Well-Differentiated Thyroid Carcinoma.

Dtsch Arztebl Int 2015 Jun;112(26):452-8

Endocrinology and Nephrology Clinic, Leipzig University Hospital, Nuclear Medicine Clinic, Leipzig University Hospital, Clinic for Nuclear Medicine, University of Duisburg-Essen, Department of Nuclear Medicine, University Hospital of Würzburg and Klinik für Nuklearmedizin, Klinikum Augsburg, Department of General, Visceral and Vascular Surgery, University Hospital of Halle (Saale), Department of Internal Medicine I, Endocrine and Diabetes Unit, University Hospital of Würzburg.

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http://dx.doi.org/10.3238/arztebl.2015.0452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515787PMC
June 2015

Frequency and clinical correlates of somatic Ying Yang 1 mutations in sporadic insulinomas.

J Clin Endocrinol Metab 2015 May 12;100(5):E776-82. Epub 2015 Mar 12.

Medizinische Klinik und Poliklinik IV (U.D.L., G.D.D., M.R., F.B.), Klinikum der Universität München, 80336 Munich, Germany; Department of Visceral, Thoracic, and Vascular Surgery (E.P.S., D.W., D.K.B.), University Hospital Giessen and Marburg GmbH, 35043 Marburg, Germany; Institute of Human Genetics (T.W., A.S., T.S., S.D., T.M., T.M.S.), Helmholtz Zentrum München, 85764 Neuherberg, Germany; Funktionsbereich Spezielle Endokrinologie (A.K., M.S.), Universitätsklinikum Düsseldorf, 40225 Düsseldorf Germany; Biobank (under the administration of the Human Tissue and Cell Research) Foundation (W.E.T.), Department of General, Visceral, Transplantation, Vascular and Thoracic Surgery, Hospital of the University of Munich, 81377 Munich, Germany; Germany Institute of Human Genetics (T.M., T.M.S.), Technische Universität München, 81675 Munich, Germany; German Centre for Cardiovascular Research Partner Site (T.M., T.M.S.), Munich Heart Alliance, 80802 Munich, Germany; Department of Medicine I (M.F.), Endocrine and Diabetes Unit, University Hospital, University of Würzburg, 97080 Würzburg, Germany; and Comprehensive Cancer Center Mainfranken (M.F.), University of Würzburg, 97080 Würzburg, Germany.

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http://dx.doi.org/10.1210/jc.2015-1100DOI Listing
May 2015

Computed tomography criteria for discrimination of adrenal adenomas and adrenocortical carcinomas: analysis of the German ACC registry.

Eur J Endocrinol 2015 Apr 19;172(4):415-22. Epub 2015 Jan 19.

ENDOC Center for Endocrine TumorsAltonaer Street 59, 20357 Hamburg, GermanyDepartment of Internal MedicineUniversity of Hamburg, Hamburg, GermanyPraenobis HamburgHamburg, GermanyDepartment of RadiologyEndocrine and Diabetes UnitDepartment of Internal Medicine I, University HospitalComprehensive Cancer Center MainfrankenUniversity of Würzburg, Würzburg, Germany ENDOC Center for Endocrine TumorsAltonaer Street 59, 20357 Hamburg, GermanyDepartment of Internal MedicineUniversity of Hamburg, Hamburg, GermanyPraenobis HamburgHamburg, GermanyDepartment of RadiologyEndocrine and Diabetes UnitDepartment of Internal Medicine I, University HospitalComprehensive Cancer Center MainfrankenUniversity of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1530/EJE-14-0916DOI Listing
April 2015

Prognostic value of aldosterone and cortisol in patients hospitalized for acutely decompensated chronic heart failure with and without mineralocorticoid receptor antagonism.

J Card Fail 2015 Mar 5;21(3):208-16. Epub 2015 Jan 5.

Cardiology, Department of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany; Comprehensive Heart Failure Center, University of Würzburg, Würzburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cardfail.2014.12.011DOI Listing
March 2015