Martin Enge

Martin Enge

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Martin Enge

Martin Enge

Publications by authors named "Martin Enge"

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22Publications

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Modeling Spatial Correlation of Transcripts with Application to Developing Pancreas.

Sci Rep 2019 Apr 3;9(1):5592. Epub 2019 Apr 3.

Department of Biomedical Data Science, Stanford University, 450 Serra Mall, Stanford, CA, 94305, USA.

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http://dx.doi.org/10.1038/s41598-019-41951-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447534PMC
April 2019

Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns.

Cell 2017 Oct 28;171(2):321-330.e14. Epub 2017 Sep 28.

Department of Bioengineering and Applied Physics, Stanford University, Stanford, CA 94305, USA; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA; Institute of Cellular Therapeutics, Allegheny Health Network, 320 East North Avenue, Pittsburgh, PA 15212, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047899PMC
October 2017

Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and Arx.

Cell Metab 2017 03 16;25(3):622-634. Epub 2017 Feb 16.

Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2017.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358097PMC
March 2017

DNA-dependent formation of transcription factor pairs alters their binding specificity.

Nature 2015 Nov 9;527(7578):384-8. Epub 2015 Nov 9.

Department of Biosciences and Nutrition, Karolinska Institutet, SE 141 83, Sweden.

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http://dx.doi.org/10.1038/nature15518DOI Listing
November 2015

CTCF/cohesin-binding sites are frequently mutated in cancer.

Nat Genet 2015 Jul 8;47(7):818-21. Epub 2015 Jun 8.

1] Genome-Scale Biology Research Program, Research Programs Unit, University of Helsinki, Helsinki, Finland. [2] Department of Medical and Clinical Genetics, Medicum, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1038/ng.3335DOI Listing
July 2015

A survey of human brain transcriptome diversity at the single cell level.

Proc Natl Acad Sci U S A 2015 Jun 18;112(23):7285-90. Epub 2015 May 18.

Departments of Bioengineering and Applied Physics, Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305

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http://www.pnas.org/lookup/doi/10.1073/pnas.1507125112
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http://dx.doi.org/10.1073/pnas.1507125112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466750PMC
June 2015

Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites.

Cell 2013 Aug;154(4):801-13

Science for Life Laboratory, Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm 14183, Sweden.

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http://dx.doi.org/10.1016/j.cell.2013.07.034DOI Listing
August 2013

Mice lacking a Myc enhancer that includes human SNP rs6983267 are resistant to intestinal tumors.

Science 2012 Dec 1;338(6112):1360-3. Epub 2012 Nov 1.

Science for Life Center, Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1126/science.1228606DOI Listing
December 2012

Inhibition of glycolytic enzymes mediated by pharmacologically activated p53: targeting Warburg effect to fight cancer.

J Biol Chem 2011 Dec 23;286(48):41600-15. Epub 2011 Aug 23.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, Nobelsväg 16, Stockholm, SE 171 77, Sweden.

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http://dx.doi.org/10.1074/jbc.M111.240812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3308870PMC
December 2011

Counting absolute numbers of molecules using unique molecular identifiers.

Nat Methods 2011 Nov 20;9(1):72-4. Epub 2011 Nov 20.

Genome-Scale Biology Program, Institute of Biomedicine, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1038/nmeth.1778DOI Listing
November 2011

Pharmacological activation of p53 triggers anticancer innate immune response through induction of ULBP2.

Cell Cycle 2011 Oct 1;10(19):3346-58. Epub 2011 Oct 1.

Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.4161/cc.10.19.17630DOI Listing
October 2011

Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo.

EMBO J 2010 Jul 1;29(13):2147-60. Epub 2010 Jun 1.

Public Health Genomics Unit, National Institute for Health and Welfare (THL) and Genome-Scale Biology Program, Institute of Biomedicine and High Throughput Center, University of Helsinki, Biomedicum, Helsinki, Finland.

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http://dx.doi.org/10.1038/emboj.2010.106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905244PMC
July 2010

Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities.

Genome Res 2010 Jun 8;20(6):861-73. Epub 2010 Apr 8.

Department of Molecular Medicine, National Public Health Institute (KTL) and Genome-Scale Biology Program, Institute of Biomedicine and High Throughput Center, University of Helsinki, Biomedicum, Helsinki, Finland.

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http://dx.doi.org/10.1101/gr.100552.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877582PMC
June 2010

Ablation of key oncogenic pathways by RITA-reactivated p53 is required for efficient apoptosis.

Cancer Cell 2009 May;15(5):441-53

Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 17177, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.ccr.2009.03.021DOI Listing
May 2009

MDM2-dependent downregulation of p21 and hnRNP K provides a switch between apoptosis and growth arrest induced by pharmacologically activated p53.

Cancer Cell 2009 Mar;15(3):171-83

Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.ccr.2009.01.019DOI Listing
March 2009

Tumor-specific induction of apoptosis by a p53-reactivating compound.

Exp Cell Res 2009 Feb 3;315(3):451-61. Epub 2008 Dec 3.

The Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Box 280, SE-171 77, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.yexcr.2008.11.009DOI Listing
February 2009

Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors.

Nat Med 2004 Dec 21;10(12):1321-8. Epub 2004 Nov 21.

Microbiology and Tumor Biology Center, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1038/nm1146DOI Listing
December 2004