Martin Eilers

Martin Eilers

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Martin Eilers

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Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase.

Nature 2019 Mar 20;567(7749):545-549. Epub 2019 Mar 20.

Theodor Boveri Institute, Department of Biochemistry and Molecular Biology, Biocenter, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1038/s41586-019-1030-9DOI Listing
March 2019

HUWE1 Ubiquitin Ligase Regulates Endoreplication and Antagonizes JNK Signaling During Salivary Gland Development.

Cells 2018 Sep 26;7(10). Epub 2018 Sep 26.

Rappaport Research Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 31096, Israel.

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http://dx.doi.org/10.3390/cells7100151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210797PMC
September 2018

The Expanding World of N-MYC-Driven Tumors.

Cancer Discov 2018 02 22;8(2):150-163. Epub 2018 Jan 22.

Theodor Boveri Institute and Comprehensive Cancer Center Mainfranken, Biocenter, University of Würzburg, Würzburg, Germany.

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http://cancerdiscovery.aacrjournals.org/lookup/doi/10.1158/2
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http://dx.doi.org/10.1158/2159-8290.CD-17-0273DOI Listing
February 2018

MYC and tumor metabolism: chicken and egg.

EMBO J 2017 12 10;36(23):3409-3420. Epub 2017 Nov 10.

Theodor Boveri Institute and Comprehensive Cancer Center Mainfranken, Biocenter, University of Würzburg, Würzburg, Germany

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http://dx.doi.org/10.15252/embj.201796438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709748PMC
December 2017

The mRNA 3'-UTR couples RNA polymerase II function to glutamine and ribonucleotide levels.

EMBO J 2017 07 13;36(13):1854-1868. Epub 2017 Apr 13.

Theodor Boveri Institute and Comprehensive Cancer Center Mainfranken, Biocenter, University of Würzburg, Würzburg, Germany

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http://dx.doi.org/10.15252/embj.201796662DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494468PMC
July 2017

A conformational switch regulates the ubiquitin ligase HUWE1.

Elife 2017 02 14;6. Epub 2017 Feb 14.

Rudolf Virchow Center for Experimental Biomedicine, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.7554/eLife.21036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5308896PMC
February 2017

MYC-induced apoptosis in mammary epithelial cells is associated with repression of lineage-specific gene signatures.

Cell Cycle 2016 ;15(3):316-23

b Theodor Boveri Institute, Biocenter, University of Würzburg, Am Hubland , Würzburg , Germany.

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http://dx.doi.org/10.1080/15384101.2015.1121351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943699PMC
December 2016

Structural basis of N-Myc binding by Aurora-A and its destabilization by kinase inhibitors.

Proc Natl Acad Sci U S A 2016 11 11;113(48):13726-13731. Epub 2016 Nov 11.

Astbury Centre for Structural and Molecular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1610626113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137718PMC
November 2016

N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer.

Cancer Cell 2016 10;30(4):563-577

Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY 10065, USA; Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA; Englander Institute for Precision Medicine, New York-Presbyterian Hospital, Weill Cornell Medicine, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540451PMC
October 2016

TEAD activity is restrained by MYC and stratifies human breast cancer subtypes.

Cell Cycle 2016 Oct 19;15(19):2551-2556. Epub 2016 Jul 19.

a Leibniz Institute on Aging, Fritz Lipmann Institute e.V. , Jena , Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053556PMC
http://dx.doi.org/10.1080/15384101.2016.1207837DOI Listing
October 2016

Different promoter affinities account for specificity in MYC-dependent gene regulation.

Elife 2016 07 27;5. Epub 2016 Jul 27.

Department of Biochemistry and Molecular Biology, Biocenter, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.7554/eLife.15161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963202PMC
July 2016

MYC regulates the antitumor immune response through CD47 and PD-L1.

Science 2016 Apr 10;352(6282):227-31. Epub 2016 Mar 10.

Division of Oncology, Departments of Medicine and Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1126/science.aac9935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940030PMC
April 2016

Ubiquitin-Dependent Turnover of MYC Antagonizes MYC/PAF1C Complex Accumulation to Drive Transcriptional Elongation.

Mol Cell 2016 Jan 10;61(1):54-67. Epub 2015 Dec 10.

Comprehensive Cancer Center Mainfranken, Versbacher Straße 5, 97078 Würzburg, Germany; Department of Radiation Oncology, University Hospital Würzburg, Josef-Schneider-Straße 11, 97080 Würzburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2015.11.007DOI Listing
January 2016

Myc coordinates transcription and translation to enhance transformation and suppress invasiveness.

EMBO Rep 2015 Dec 4;16(12):1723-36. Epub 2015 Nov 4.

Division of Biological Stress Response, The Netherlands Cancer Institute, Amsterdam, The Netherlands Erasmus MC, Rotterdam University, Rotterdam, The Netherlands

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http://dx.doi.org/10.15252/embr.201540717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687422PMC
December 2015

A MYC-Driven Change in Mitochondrial Dynamics Limits YAP/TAZ Function in Mammary Epithelial Cells and Breast Cancer.

Cancer Cell 2015 Dec;28(6):743-757

Theodor Boveri Institute, Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany; Comprehensive Cancer Center Mainfranken, University of Würzburg, Josef-Schneider-Straße 6, 97080 Würzburg, Germany. Electronic address:

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http://www.cell.com/cancer-cell/pdf/S1535-6108(15)00390-6.pd
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http://linkinghub.elsevier.com/retrieve/pii/S153561081500390
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http://dx.doi.org/10.1016/j.ccell.2015.10.013DOI Listing
December 2015

Repression of SRF target genes is critical for Myc-dependent apoptosis of epithelial cells.

EMBO J 2015 Jun 20;34(11):1554-71. Epub 2015 Apr 20.

Biocenter Theodor Boveri Institute University of Würzburg, Würzburg, Germany Comprehensive Cancer Center Mainfranken University of Würzburg, Würzburg, Germany

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http://dx.doi.org/10.15252/embj.201490467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474530PMC
June 2015

Taming of the beast: shaping Myc-dependent amplification.

Trends Cell Biol 2015 Apr 1;25(4):241-8. Epub 2014 Dec 1.

Laboratory of Pathology, 10 Center Drive, Bethesda, MD 20892-1500, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tcb.2014.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380620PMC
April 2015

Usp28 counteracts Fbw7 in intestinal homeostasis and cancer.

Cancer Res 2015 Apr 25;75(7):1181-6. Epub 2015 Feb 25.

Mammalian Genetics Laboratory, Cancer Research UK London Research Institute, Lincoln's Inn Fields Laboratories, Lincoln's Inn Fields, London, United Kingdom. School of Medicine, King's College London, Guy's Campus, London, United Kingdom.

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http://cancerres.aacrjournals.org/content/canres/early/2015/
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-14-1726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384988PMC
April 2015

Mechanisms of epigenetic and cell-type specific regulation of Hey target genes in ES cells and cardiomyocytes.

J Mol Cell Cardiol 2015 Feb 13;79:79-88. Epub 2014 Nov 13.

Developmental Biochemistry, Theodor Boveri Institute (Biocenter), University of Wuerzburg, Am Hubland, D-97074 Wuerzburg, Germany; Comprehensive Cancer Center Mainfranken, University of Wuerzburg, Am Hubland, D-97074 Wuerzburg, Germany; Comprehensive Heart Failure Center, University of Wuerzburg, Am Hubland, D-97074 Wuerzburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2014.11.004DOI Listing
February 2015

Dual regulation of Fbw7 function and oncogenic transformation by Usp28.

Cell Rep 2014 Nov 30;9(3):1099-109. Epub 2014 Oct 30.

Department of Biochemistry and Molecular Biology, Biozentrum, University of Würzburg, Am Hubland, 97074 Würzburg, Germany; Comprehensive Cancer Center Mainfranken and Department of Radiation Oncology, University Hospital Würzburg, Versbacher Strasse 5, 97078 Würzburg, Germany. Electronic address:

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http://www.cell.com/cell-reports/pdf/S2211-1247(14)00840-7.p
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http://linkinghub.elsevier.com/retrieve/pii/S221112471400840
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http://dx.doi.org/10.1016/j.celrep.2014.09.057DOI Listing
November 2014

In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer.

Nat Med 2014 Oct 14;20(10):1138-46. Epub 2014 Sep 14.

1] Division of Translational Gastrointestinal Oncology, Department of Internal Medicine I, University of Tuebingen, Tuebingen, Germany. [2] Translational Gastrointestinal Oncology Group within the German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nm.3679DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587571PMC
October 2014

Drugging MYCN through an allosteric transition in Aurora kinase A.

Cancer Cell 2014 Sep 28;26(3):414-427. Epub 2014 Aug 28.

Department of Pediatrics, UCSF Benioff Children's Hospital, University of California, San Francisco, San Francisco, CA 94158, USA; Departments of Neurology and Neurological Surgery, University of California, San Francisco, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.07.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160413PMC
September 2014

BIM is the primary mediator of MYC-induced apoptosis in multiple solid tissues.

Cell Rep 2014 Sep 28;8(5):1347-53. Epub 2014 Aug 28.

Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK; Theodor Boveri Institute, Biocentre, University of Wuerzburg, Am Hubland, 97074 Wuerzburg, Germany; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK. Electronic address:

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http://www.cell.com/cell-reports/pdf/S2211-1247(14)00659-7.p
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http://linkinghub.elsevier.com/retrieve/pii/S221112471400659
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http://dx.doi.org/10.1016/j.celrep.2014.07.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231288PMC
September 2014

Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles.

Nature 2014 Jul 9;511(7510):483-7. Epub 2014 Jul 9.

1] Theodor Boveri Institute, Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany [2] Comprehensive Cancer Center Mainfranken, University of Würzburg, Josef-Schneider-Str. 6, 97080 Würzburg, Germany [3].

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http://dx.doi.org/10.1038/nature13473DOI Listing
July 2014

CIP2A influences survival in colon cancer and is critical for maintaining Myc expression.

PLoS One 2013 1;8(10):e75292. Epub 2013 Oct 1.

Department of General, Visceral, Vascular and Paediatric Surgery (Department of Surgery I), University Hospital Wuerzburg, Wuerzburg, Germany ; Department of Biochemistry and Molecular Biology, University of Wuerzburg, Wuerzburg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0075292PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788051PMC
June 2014

Inflammation-induced NFATc1-STAT3 transcription complex promotes pancreatic cancer initiation by KrasG12D.

Cancer Discov 2014 Jun 2;4(6):688-701. Epub 2014 Apr 2.

Authors' Affiliations:Signaling and Transcription Laboratory, Department of Gastroenterology, Philipps University, Marburg; Department of Gastroenterology and Gastrointestinal Oncology, University Medical Center Göttingen, Göttingen; II. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität; Institute of Pathology, Helmholtz Zentrum, Munich; Theodor Boveri Institute, University of Würzburg, Würzburg; Institute for Genetics, Justus-Liebig-University, Giessen, Germany; Schulze Center for Novel Therapeutics, Division of Oncology Research; Divisions of Anatomic Pathology and Biostatistics, College of Medicine; Laboratory of Epigenetics and Chromatin Dynamics, Department of Medicine, Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota; Barrow Brain Tumor Research Center, St. Joseph's Hospital and Medical Center, Phoenix, Arizona; and Cold Spring Harbor Laboratory, Cold Spring Harbor, New York

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http://dx.doi.org/10.1158/2159-8290.CD-13-0593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069603PMC
June 2014

Miz1 is required to maintain autophagic flux.

Nat Commun 2013 ;4:2535

1] Theodor Boveri Institute, Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany [2].

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http://dx.doi.org/10.1038/ncomms3535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084558PMC
May 2014

The role of MIZ-1 in MYC-dependent tumorigenesis.

Cold Spring Harb Perspect Med 2013 Dec 1;3(12):a014290. Epub 2013 Dec 1.

Comprehensive Cancer Center Mainfranken and Theodor Boveri Institute, Biocenter, University of Würzburg, 97074 Würzburg, Germany.

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http://dx.doi.org/10.1101/cshperspect.a014290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839600PMC
December 2013

Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-δ.

Nat Immunol 2013 May 24;14(5):461-9. Epub 2013 Mar 24.

Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

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http://dx.doi.org/10.1038/ni.2566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3631447PMC
May 2013

Deregulated MYC expression induces dependence upon AMPK-related kinase 5.

Nature 2012 Mar 28;483(7391):608-12. Epub 2012 Mar 28.

Theodor Boveri Institute, Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany.

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http://dx.doi.org/10.1038/nature10927DOI Listing
March 2012

The human papillomavirus type 16 E7 oncoprotein targets Myc-interacting zinc-finger protein-1.

Virology 2012 Jan 17;422(2):242-53. Epub 2011 Nov 17.

Cell Metabolism and Differentiation Research Group, Institute for Biomedical Aging Research of the Austrian Academy of Sciences, Innsbruck, Austria.

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http://dx.doi.org/10.1016/j.virol.2011.10.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268862PMC
January 2012

PI3K-dependent phosphorylation of Fbw7 modulates substrate degradation and activity.

FEBS Lett 2011 Jul 24;585(14):2151-7. Epub 2011 May 24.

Theodor Boveri Institute, Biocenter, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1016/j.febslet.2011.05.036DOI Listing
July 2011

Pluripotency without Max.

Cell Stem Cell 2011 Jul;9(1):5-6

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http://dx.doi.org/10.1016/j.stem.2011.06.010DOI Listing
July 2011

Addicted to Myc--but why?

Genes Dev 2011 May;25(9):895-7

Theodor Boveri Institute, Biocenter, University of Würzburg, Würzburg 97074, Germany.

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http://dx.doi.org/10.1101/gad.2053311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084022PMC
May 2011

The first Sino-German Symposium on DNA Repair and Human Diseases.

DNA Repair (Amst) 2011 Mar 2;10(3):349-54. Epub 2011 Feb 2.

Laboratory of Cancer Biology, Capital Normal University, Beijing, China. Xingzhi

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http://dx.doi.org/10.1016/j.dnarep.2011.01.006DOI Listing
March 2011

Ubiquitylation of the amino terminus of Myc by SCF(β-TrCP) antagonizes SCF(Fbw7)-mediated turnover.

Nat Cell Biol 2010 Oct 19;12(10):973-81. Epub 2010 Sep 19.

Theodor Boveri Institute, Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany.

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http://www.nature.com/articles/ncb2104
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http://dx.doi.org/10.1038/ncb2104DOI Listing
October 2010

Sequential activation of NFAT and c-Myc transcription factors mediates the TGF-beta switch from a suppressor to a promoter of cancer cell proliferation.

J Biol Chem 2010 Aug 1;285(35):27241-50. Epub 2010 Jun 1.

Signal Transduction and Transcription Laboratory, Department of Gastroenterology and Endocrinology, Philipps-University of Marburg, 35043 Marburg, Germany.

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http://dx.doi.org/10.1074/jbc.M110.100438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930723PMC
August 2010

Gene expression analysis after receptor tyrosine kinase activation reveals new potential melanoma proteins.

BMC Cancer 2010 Jul 21;10:386. Epub 2010 Jul 21.

Department of Physiological Chemistry I, Biocenter, University of Wurzburg, Wurzburg, Germany.

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http://dx.doi.org/10.1186/1471-2407-10-386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912872PMC
July 2010

Transcriptional repression: the dark side of myc.

Genes Cancer 2010 Jun;1(6):580-6

Theodor-Boveri-Institute, Biozentrum, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1177/1947601910379012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092225PMC
June 2010

Miz1 is a signal- and pathway-specific modulator or regulator (SMOR) that suppresses TNF-alpha-induced JNK1 activation.

Proc Natl Acad Sci U S A 2009 Oct 7;106(43):18279-84. Epub 2009 Oct 7.

Ben May Department for Cancer Research, University of Chicago, Chicago, IL 60637, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0906328106
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http://dx.doi.org/10.1073/pnas.0906328106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775337PMC
October 2009

Compassionate use of sorafenib in FLT3-ITD-positive acute myeloid leukemia: sustained regression before and after allogeneic stem cell transplantation.

Blood 2009 Jun 23;113(26):6567-71. Epub 2009 Apr 23.

Philipps University of Marburg, Medical Center of the University Giessen and Marburg, Campus Marburg, Department of Hematology, Oncology and Immunology, Marburg, Germany.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2009-03-20
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http://dx.doi.org/10.1182/blood-2009-03-208298DOI Listing
June 2009

Facilitating replication under stress: an oncogenic function of MYC?

Nat Rev Cancer 2009 Jun;9(6):441-4

Theodor-Boveri-Institute, Physiological Chemistry Biocenter Am Hubland, Würzburg, Germany.

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http://dx.doi.org/10.1038/nrc2640DOI Listing
June 2009

HCT116 cells deficient in p21(Waf1) are hypersensitive to tyrosine kinase inhibitors and adriamycin through a mechanism unrelated to p21 and dependent on p53.

DNA Repair (Amst) 2009 Mar 15;8(3):390-9. Epub 2009 Jan 15.

Dpto de Biología Molecular, Instituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria-CSIC-IDICAN, Santander, Spain.

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http://linkinghub.elsevier.com/retrieve/pii/S156878640800425
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http://dx.doi.org/10.1016/j.dnarep.2008.12.001DOI Listing
March 2009

An unsteady scaffold for Myc.

EMBO J 2009 Mar;28(5):453-4

Institute of Molecular Biology and Tumor Research, Philipps University Marburg, Universität Marburg, Marburg, Germany.

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http://dx.doi.org/10.1038/emboj.2009.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657581PMC
March 2009

Myc increases self-renewal in neural progenitor cells through Miz-1.

J Cell Sci 2008 Dec 11;121(Pt 23):3941-50. Epub 2008 Nov 11.

Developmental Biology, Institute of Biomedicine, Haartmaninkatu 8, PO Box 63, 00014 University of Helsinki, Finland.

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http://dx.doi.org/10.1242/jcs.024802DOI Listing
December 2008

Miz1 and HectH9 regulate the stability of the checkpoint protein, TopBP1.

EMBO J 2008 Nov 16;27(21):2851-61. Epub 2008 Oct 16.

Institute of Molecular Biology and Tumor Research, Philipps University Marburg, Marburg, Germany.

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http://dx.doi.org/10.1038/emboj.2008.200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2580782PMC
November 2008

Myc's broad reach.

Genes Dev 2008 Oct;22(20):2755-66

Institute of Molecular Biology and Tumor Research, 35033 Marburg, Germany.

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http://dx.doi.org/10.1101/gad.1712408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751281PMC
October 2008

A ribosomal protein L23-nucleophosmin circuit coordinates Mizl function with cell growth.

Nat Cell Biol 2008 Sep;10(9):1051-61

Institute for Molecular Biology and Tumor Research (IMT), Emil-Mannkopff-Str.2, 35033 Marburg, Germany.

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September 2008

Fbw7 and Usp28 regulate myc protein stability in response to DNA damage.

Cell Cycle 2007 Oct 26;6(19):2327-31. Epub 2007 Jul 26.

Institute of Molecular Biology and Tumor Research, Emil-Mannkopff-Str. 2, Marburg, Germany.

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http://dx.doi.org/10.4161/cc.6.19.4804DOI Listing
October 2007

Miz1 is required for hair follicle structure and hair morphogenesis.

J Cell Sci 2007 Aug 17;120(Pt 15):2586-93. Epub 2007 Jul 17.

Institute for Cell Biology, University of Marburg, Robert-Koch-Str. 6, 35033 Marburg, Germany.

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http://dx.doi.org/10.1242/jcs.007104DOI Listing
August 2007

PIM1 and MYC: a changing relationship?

Nat Cell Biol 2007 Aug;9(8):873-5

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http://dx.doi.org/10.1038/ncb0807-873DOI Listing
August 2007

The ubiquitin-specific protease USP28 is required for MYC stability.

Nat Cell Biol 2007 Jul 10;9(7):765-74. Epub 2007 Jun 10.

Institute of Molecular Biology and Tumor Research, Emil-Mannkopff-Str.2, 35033 Marburg, Germany.

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http://www.nature.com/articles/ncb1601
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http://dx.doi.org/10.1038/ncb1601DOI Listing
July 2007

Control of cell proliferation and growth by Myc proteins.

Results Probl Cell Differ 2006 ;42:329-42

Institute for Molecular Biology and Tumor Research, University of Marburg, Germany.

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September 2006

Silencing of the meiotic genes SMC1beta and STAG3 in somatic cells by E2F6.

J Biol Chem 2005 Dec 19;280(50):41380-6. Epub 2005 Oct 19.

Institute for Molecular Biology and Tumor Research (IMT), Philipps-University Marburg, 35037 Marburg, Germany.

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http://dx.doi.org/10.1074/jbc.M506797200DOI Listing
December 2005

All-trans retinoic acid treatment of Wilms tumor cells reverses expression of genes associated with high risk and relapse in vivo.

Oncogene 2005 Aug;24(33):5246-51

Physiological Chemistry I, Theodor-Boveri-Institute, Biocenter of the University of Wuerzburg, Wuerzburg 97074, Germany.

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http://dx.doi.org/10.1038/sj.onc.1208725DOI Listing
August 2005

Transcriptional regulation and transformation by Myc proteins.

Nat Rev Mol Cell Biol 2005 Aug;6(8):635-45

Institute for Molecular Biology and Tumour Research, University of Marburg, Emil-Mannkopff-Strasse 2, 35033 Marburg, Germany.

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http://dx.doi.org/10.1038/nrm1703DOI Listing
August 2005

Inhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells. Microarray analysis reveals defective induction of p53 target genes and upregulation of chaperone genes.

Oncogene 2005 Jun;24(28):4559-71

Departamento de Biología Molecular y Unidad de Biomedicina-CSIC, Grupo de Biología Molecular del Cáncer, Facultad de Medicina, University of Cantabria, Santander 39011, Spain.

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http://dx.doi.org/10.1038/sj.onc.1208652DOI Listing
June 2005

Mad1 function in cell proliferation and transcriptional repression is antagonized by cyclin E/CDK2.

J Biol Chem 2005 Apr 18;280(16):15489-92. Epub 2005 Feb 18.

Abteilung Biochemie und Molekularbiologie, Institut für Biochemie, and Institut für Arbeitsmedizin, Klinikum der RWTH, 52057 Aachen, Germany.

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http://dx.doi.org/10.1074/jbc.C400611200DOI Listing
April 2005

Pontin and Reptin regulate cell proliferation in early Xenopus embryos in collaboration with c-Myc and Miz-1.

Mech Dev 2005 Apr 22;122(4):545-56. Epub 2005 Jan 22.

Zoologisches Institut II, Universität Karlsruhe (TH), Kaiserstrasse 12, 76131 Karlsruhe, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S092547730400275
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http://dx.doi.org/10.1016/j.mod.2004.11.010DOI Listing
April 2005

Selective ablation of retinoblastoma protein function by the RET finger protein.

Mol Cell 2005 Apr;18(2):213-24

Centre for Cell and Molecular Biology, Chester Beatty Laboratories, 237 Fulham Road, SW3 6JB London, United Kingdom.

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http://dx.doi.org/10.1016/j.molcel.2005.03.009DOI Listing
April 2005

Akt and 14-3-3eta regulate Miz1 to control cell-cycle arrest after DNA damage.

Nat Cell Biol 2005 Jan 5;7(1):30-41. Epub 2004 Dec 5.

Institute for Molecular Biology and Tumor Research, University of Marburg, Emil-Mannkopff-Strasse 2, 35033 Marburg, Germany.

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http://dx.doi.org/10.1038/ncb1202DOI Listing
January 2005

Myc-induced proliferation and transformation require Akt-mediated phosphorylation of FoxO proteins.

EMBO J 2004 Jul 8;23(14):2830-40. Epub 2004 Jul 8.

Institute for Molecular Biology and Tumor Research, Marburg, Germany.

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http://dx.doi.org/10.1038/sj.emboj.7600279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC514943PMC
July 2004

DeltaNp73 can modulate the expression of various genes in a p53-independent fashion.

Oncogene 2003 Nov;22(51):8246-54

Institut für Virologie, Philipps-Universität Marburg, Robert Koch Str. 17, Marburg 35037, Germany.

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http://dx.doi.org/10.1038/sj.onc.1207138DOI Listing
November 2003