Martin Dugas

Martin Dugas

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Martin Dugas

Martin Dugas

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100Publications

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Benchmarking of 4C-seq pipelines based on real and simulated data.

Authors:
Carolin Walter Daniel Schuetzmann Frank Rosenbauer Martin Dugas

Bioinformatics 2019 Dec;35(23):4938-4945

Institute of Medical Informatics, University of Münster, Münster, Germany.

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https://academic.oup.com/bioinformatics/advance-article/doi/
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http://dx.doi.org/10.1093/bioinformatics/btz426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901067PMC
December 2019

Infectious stimuli promote malignant B-cell acute lymphoblastic leukemia in the absence of AID.

Authors:
Guillermo Rodríguez-Hernández Friederike V Opitz Pilar Delgado Carolin Walter Ángel F Álvarez-Prado Inés González-Herrero Franziska Auer Ute Fischer Stefan Janssen Christoph Bartenhagen Javier Raboso-Gallego Ana Casado-García Alberto Orfao Oscar Blanco Diego Alonso-López Javier De Las Rivas Sara González de Tena-Dávila Markus Müschen Martin Dugas Francisco Javier García Criado María Begoña García Cenador Carolina Vicente-Dueñas Julia Hauer Almudena R Ramiro Isidro Sanchez-Garcia Arndt Borkhardt

Nat Commun 2019 Dec 5;10(1):5563. Epub 2019 Dec 5.

Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, Heinrich Heine University, Moorenstrasse 5, 40225, Düsseldorf, Germany.

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http://dx.doi.org/10.1038/s41467-019-13570-yDOI Listing
December 2019

StudyPortal - Geovisualization of Study Research Networks.

Authors:
Julian Varghese Michael Fujarski Martin Dugas

J Med Syst 2019 Dec 10;44(1):22. Epub 2019 Dec 10.

Institute of Medical Informatics, University of Münster, Albert-Schweitzer-Campus 1, Gebäude A11, 48149, Münster, Germany.

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http://dx.doi.org/10.1007/s10916-019-1493-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904404PMC
December 2019

Macrophage-tumor cell interaction promotes ATRT progression and chemoresistance.

Authors:
Viktoria Melcher Monika Graf Marta Interlandi Natalia Moreno Flavia W de Faria Su Na Kim Dennis Kastrati Sonja Korbanka Amelie Alfert Joachim Gerß Gerd Meyer Zu Hörste Wolfgang Hartmann Michael C Frühwald Martin Dugas Ulrich Schüller Martin Hasselblatt Thomas K Albert Kornelius Kerl

Acta Neuropathol 2019 Dec 17. Epub 2019 Dec 17.

Department of Pediatric Hematology and Oncology, University Children's Hospital Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany.

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http://dx.doi.org/10.1007/s00401-019-02116-7DOI Listing
December 2019

EMR-integrated minimal core dataset for routine health care and multiple research settings: A case study for neuroinflammatory demyelinating diseases.

Authors:
Sophia von Martial Tobias J Brix Luisa Klotz Philipp Neuhaus Klaus Berger Clemens Warnke Sven G Meuth Heinz Wiendl Martin Dugas

PLoS One 2019 15;14(10):e0223886. Epub 2019 Oct 15.

Institute of Medical Informatics, University of Münster, Münster, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0223886PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6793844PMC
October 2019

Reviving 30 Year Old Technology: Lessons Learned from Transferring Patient Data Using Data Matrix Codes.

Authors:
Tobias Johannes Brix Philipp Neuhaus Michael Storck Iñaki Soto-Rey Martin Dugas

Stud Health Technol Inform 2019 ;258:90-94

Institute of Medical Informatics, University of Münster, Germany.

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August 2019

Interoperability Improvement of Mobile Patient Survey (MoPat) Implementing Fast Health Interoperability Resources (FHIR).

Authors:
Michael Storck Luca Hollenberg Martin Dugas Iñaki Soto-Rey

Stud Health Technol Inform 2019 ;258:141-145

Institute of Medical Informatics, University of Muenster, Muenster, Germany.

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August 2019

StudyPortal - A Novel Method to Visualize Study Research Networks.

Authors:
Julian Varghese Michael Fujarski Martin Dugas

Stud Health Technol Inform 2019 ;258:163

Institute of Medical Informatics, University of Münster, Germany.

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August 2019

Portal of Medical Data Models: Status 2018.

Authors:
Sarah Riepenhausen Julian Varghese Philipp Neuhaus Michael Storck Alexandra Meidt Stefan Hegselmann Martin Dugas

Stud Health Technol Inform 2019 ;258:239-240

Institute of Medical Informatics, University of Münster, Germany.

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August 2019

Core Data Elements in Acute Myeloid Leukemia: A Unified Medical Language System-Based Semantic Analysis and Experts' Review.

Authors:
Christian Holz Torsten Kessler Martin Dugas Julian Varghese

JMIR Med Inform 2019 Aug 12;7(3):e13554. Epub 2019 Aug 12.

Institute of Medical Informatics, University of Münster, Münster, Germany.

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http://dx.doi.org/10.2196/13554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709897PMC
August 2019

Compatible Data Models at Design Stage of Medical Information Systems: Leveraging Related Data Elements from the MDM Portal.

Authors:
Martin Dugas Stefan Hegselmann Sarah Riepenhausen Philipp Neuhaus Leonard Greulich Alexandra Meidt Julian Varghese

Stud Health Technol Inform 2019 Aug;264:113-117

Institute of Medical Informatics, University of Münster, Germany.

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http://dx.doi.org/10.3233/SHTI190194DOI Listing
August 2019

Electronic Image Documentation of Patient Reported Outcomes Using Mobile Technologies.

Authors:
Iñaki Soto-Rey Tobias Hardt Luca Hollenberg Philipp Bruland Sonja Ständer Martin Dugas Michael Storck

Stud Health Technol Inform 2019 Aug;264:1779-1780

Institute of Medical Informatics, University of Münster, Münster, Germany.

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http://dx.doi.org/10.3233/SHTI190644DOI Listing
August 2019

Common Data Elements for Acute Coronary Syndrome: Analysis Based on the Unified Medical Language System.

Authors:
Markus Kentgen Julian Varghese Alexander Samol Johannes Waltenberger Martin Dugas

JMIR Med Inform 2019 Aug 23;7(3):e14107. Epub 2019 Aug 23.

Institute of Medical Informatics, University of Münster, Münster, Germany.

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http://dx.doi.org/10.2196/14107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6729118PMC
August 2019

Establishing risk-adjusted quality indicators in surgery using administrative data-an example from neurosurgery.

Authors:
Stephanie Schipmann Julian Varghese Tobias Brix Michael Schwake Dennis Keurhorst Sebastian Lohmann Eric Suero Molina Uwe Max Mauer Martin Dugas Nils Warneke Walter Stummer

Acta Neurochir (Wien) 2019 06 26;161(6):1057-1065. Epub 2019 Apr 26.

Department of Neurosurgery, University Hospital Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany.

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http://dx.doi.org/10.1007/s00701-018-03792-2DOI Listing
June 2019

Genetic alterations in human papillomavirus-associated oropharyngeal squamous cell carcinoma of patients with treatment failure.

Authors:
Henrike Reder Steffen Wagner Ulrike Gamerdinger Sarah Sandmann Nora Wuerdemann Andreas Braeuninger Martin Dugas Stefan Gattenloehner Jens Peter Klussmann Claus Wittekindt

Oral Oncol 2019 Jun 28;93:59-65. Epub 2019 Apr 28.

Department of Otorhinolaryngology, Head and Neck Surgery, Justus-Liebig University Giessen, 35392 Giessen, Germany.

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http://dx.doi.org/10.1016/j.oraloncology.2019.04.013DOI Listing
June 2019

Safeguard function of PU.1 shapes the inflammatory epigenome of neutrophils.

Authors:
Josephine Fischer Carolin Walter Alexander Tönges Hanna Aleth Marta Joana Costa Jordão Mathias Leddin Verena Gröning Tabea Erdmann Georg Lenz Johannes Roth Thomas Vogl Marco Prinz Martin Dugas Ilse D Jacobsen Frank Rosenbauer

Nat Immunol 2019 05 25;20(5):546-558. Epub 2019 Mar 25.

Institute of Molecular Tumor Biology, University of Muenster, Muenster, Germany.

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http://www.nature.com/articles/s41590-019-0343-z
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http://dx.doi.org/10.1038/s41590-019-0343-zDOI Listing
May 2019

ODM Data Analysis-A tool for the automatic validation, monitoring and generation of generic descriptive statistics of patient data.

Authors:
Tobias Johannes Brix Philipp Bruland Saad Sarfraz Jan Ernsting Philipp Neuhaus Michael Storck Justin Doods Sonja Ständer Martin Dugas

PLoS One 2018 22;13(6):e0199242. Epub 2018 Jun 22.

Institute of Medical Informatics, University of Münster, Münster, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199242PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014674PMC
April 2019

Adverse events in brain tumor surgery: incidence, type, and impact on current quality metrics.

Authors:
Stephanie Schipmann Tobias Brix Julian Varghese Nils Warneke Michael Schwake Benjamin Brokinkel Christian Ewelt Martin Dugas Walter Stummer

Acta Neurochir (Wien) 2019 02 11;161(2):287-306. Epub 2019 Jan 11.

Department of Neurosurgery, University Hospital Münster, Albert-Schweitzer-Campus 1, 48149, Münster, Germany.

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http://link.springer.com/10.1007/s00701-018-03790-4
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http://dx.doi.org/10.1007/s00701-018-03790-4DOI Listing
February 2019

A Smart Device System to Identify New Phenotypical Characteristics in Movement Disorders.

Authors:
Julian Varghese Stephan Niewöhner Iñaki Soto-Rey Stephanie Schipmann-Miletić Nils Warneke Tobias Warnecke Martin Dugas

Front Neurol 2019 30;10:48. Epub 2019 Jan 30.

Institute of Medical Informatics, University of Münster, Münster, Germany.

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http://dx.doi.org/10.3389/fneur.2019.00048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363699PMC
January 2019

appreci8: a pipeline for precise variant calling integrating 8 tools.

Authors:
Sarah Sandmann Mohsen Karimi Aniek O de Graaf Christian Rohde Stefanie Göllner Julian Varghese Jan Ernsting Gunilla Walldin Bert A van der Reijden Carsten Müller-Tidow Luca Malcovati Eva Hellström-Lindberg Joop H Jansen Martin Dugas

Bioinformatics 2018 12;34(24):4205-4212

Institute of Medical Informatics, University of Münster, Münster, Germany.

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http://dx.doi.org/10.1093/bioinformatics/bty518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289140PMC
December 2018

Temporal autoregulation during human PU.1 locus SubTAD formation.

Authors:
Daniel Schuetzmann Carolin Walter Boet van Riel Sabrina Kruse Thorsten König Tabea Erdmann Alexander Tönges Eric Bindels Andre Weilemann Claudia Gebhard Klaus Wethmar Chiara Perrod Julia Minderjahn Michael Rehli Ruud Delwel Georg Lenz Stefan Gröschel Martin Dugas Frank Rosenbauer

Blood 2018 12 12;132(25):2643-2655. Epub 2018 Oct 12.

Institute of Molecular Tumor Biology and.

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http://www.bloodjournal.org/lookup/doi/10.1182/blood-2018-02
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http://dx.doi.org/10.1182/blood-2018-02-834721DOI Listing
December 2018

A Web Service to Suggest Semantic Codes Based on the MDM-Portal.

Authors:
Stefan Hegselmann Michael Storck Sophia Geßner Philipp Neuhaus Julian Varghese Martin Dugas

Stud Health Technol Inform 2018 ;253:35-39

Institute of Medical Informatics, University of Münster, Germany.

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November 2018

Conducting a Multilingual Study Researching Traumatised Refugees Utilizing a Patient-Reported Outcome System.

Authors:
Michael Storck Gundula Christians Birgit Möller Martin Dugas Iñaki Soto-Rey

Stud Health Technol Inform 2018 ;253:109-113

Institute of Medical Informatics, University of Muenster, Muenster, Germany.

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November 2018

Connecting healthcare and clinical research: Workflow optimizations through seamless integration of EHR, pseudonymization services and EDC systems.

Authors:
Philipp Bruland Justin Doods Tobias Brix Martin Dugas Michael Storck

Int J Med Inform 2018 11 10;119:103-108. Epub 2018 Sep 10.

Institute of Medical Informatics, University of Münster, Münster, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S13865056183023
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http://dx.doi.org/10.1016/j.ijmedinf.2018.09.007DOI Listing
November 2018

Web-Based Information Infrastructure Increases the Interrater Reliability of Medical Coders: Quasi-Experimental Study.

Authors:
Julian Varghese Sarah Sandmann Martin Dugas

J Med Internet Res 2018 10 15;20(10):e274. Epub 2018 Oct 15.

Institute of Medical Informatics, European Research Center for Information Systems, Münster, Germany.

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http://preprints.jmir.org/preprint/9644/accepted
Publisher Site
http://dx.doi.org/10.2196/jmir.9644DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231825PMC
October 2018

Humanistic burden of chronic pruritus in patients with inflammatory dermatoses: Results of the European Academy of Dermatology and Venereology Network on Assessment of Severity and Burden of Pruritus (PruNet) cross-sectional trial.

Authors:
Sabine Steinke Claudia Zeidler Claudia Riepe Philipp Bruland Iñaki Soto-Rey Michael Storck Matthias Augustin Svetlana Bobko Simone Garcovich Franz J Legat Andrey Lvov Laurent Misery Nani Osada Adam Reich Ekin Şavk Esther Serra-Baldrich Markus Streit Jacek C Szepietowski Wolfgang Weger Martin Dugas Sonja Ständer

J Am Acad Dermatol 2018 Sep;79(3):457-463.e5

Center for Chronic Pruritus, Department of Dermatology, University Hospital of Münster, Münster, Germany.

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http://dx.doi.org/10.1016/j.jaad.2018.04.044DOI Listing
September 2018

CDEGenerator: an online platform to learn from existing data models to build model registries.

Authors:
Julian Varghese Michael Fujarski Stefan Hegselmann Philipp Neuhaus Martin Dugas

Clin Epidemiol 2018 10;10:961-970. Epub 2018 Aug 10.

Institute of Medical Informatics, University of Münster,

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http://dx.doi.org/10.2147/CLEP.S170075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089100PMC
August 2018

Lmo2 expression defines tumor cell identity during T-cell leukemogenesis.

Authors:
Idoia García-Ramírez Sanil Bhatia Guillermo Rodríguez-Hernández Inés González-Herrero Carolin Walter Sara González de Tena-Dávila Salma Parvin Oskar Haas Wilhelm Woessmann Martin Stanulla Martin Schrappe Martin Dugas Yasodha Natkunam Alberto Orfao Verónica Domínguez Belén Pintado Oscar Blanco Diego Alonso-López Javier De Las Rivas Alberto Martín-Lorenzo Rafael Jiménez Francisco Javier García Criado María Begoña García Cenador Izidore S Lossos Carolina Vicente-Dueñas Arndt Borkhardt Julia Hauer Isidro Sánchez-García

EMBO J 2018 07 7;37(14). Epub 2018 Jun 7.

Experimental Therapeutics and Translational Oncology Program, Instituto de Biología Molecular y Celular del Cáncer, CSIC-USAL, Salamanca, Spain

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http://dx.doi.org/10.15252/embj.201798783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043907PMC
July 2018

Operational Data Model Conversion to ResearchKit.

Authors:
Iñaki Soto-Rey Sophia Geßner Martin Dugas

Stud Health Technol Inform 2017 ;245:225-229

Institute of Medical Informatics, University of Münster, Germany.

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June 2018

A Secure Architecture to Provide a Medical Emergency Dataset for Patients in Germany and Abroad.

Authors:
Michael Storck Jan Wohlmann Sarah Krudwig Alexander Vogel Judith Born Thomas Weber Martin Dugas Christian Juhra

Stud Health Technol Inform 2017 ;245:230-234

Office for eHealth, University Hospital Muenster, Muenster, Germany.

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June 2018

What Information Does Your EHR Contain? Automatic Generation of a Clinical Metadata Warehouse (CMDW) to Support Identification and Data Access Within Distributed Clinical Research Networks.

Authors:
Philipp Bruland Justin Doods Michael Storck Martin Dugas

Stud Health Technol Inform 2017 ;245:313-317

Institute of Medical Informatics, University of Münster, Münster, Germany.

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June 2018

The Portal of Medical Data Models: Where Have We Been and Where Are We Going?

Authors:
Sophia Geßner Philipp Neuhaus Julian Varghese Philipp Bruland Alexandra Meidt Iñaki Soto-Rey Michael Storck Justin Doods Martin Dugas

Stud Health Technol Inform 2017 ;245:858-862

Institute of Medical Informatics, University of Münster, Münster, Germany.

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June 2018

Medical Effect of Venous Thromboembolism Prophylaxis Systems and Common Input Categories: Preliminary Findings from a Systematic Review.

Authors:
Julian Varghese Maren Kleine Sophia Isabella Gessner Sarah Sandmann Martin Dugas

Stud Health Technol Inform 2017 ;245:1175-1179

Institute of Medical Informatics, University of Münster, Münster, Germany.

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June 2018

Integrating x4T-EDC into an Image-Portal to Establish an Ophthalmic Reading Center.

Authors:
Philipp Bruland Ulrich Kathöfer Maximilian Treder Nicole Eter Martin Dugas

Stud Health Technol Inform 2017 ;245:1254

Institute of Medical Informatics, University Hospital Münster, Münster, Germany.

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June 2018

VIPER: a web application for rapid expert review of variant calls.

Authors:
Marius Wöste Martin Dugas

Bioinformatics 2018 06;34(11):1928-1929

Institute of Medical Informatics, University of Münster, Münster 48149, Germany.

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http://dx.doi.org/10.1093/bioinformatics/bty022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972565PMC
June 2018

Compatibility Between Metadata Standards: Import Pipeline of CDISC ODM to the Samply.MDR.

Authors:
Ann-Kristin Kock-Schoppenhauer Hannes Ulrich Stefanie Wagen-Zink Petra Duhm-Harbeck Josef Ingenerf Philipp Neuhaus Martin Dugas Philipp Bruland

Stud Health Technol Inform 2018 ;247:221-225

Institute of Medical Informatics, University of Münster, Germany.

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June 2018

Standardising the Development of ODM Converters: The ODMToolBox.

Authors:
Iñaki Soto-Rey Philipp Neuhaus Philipp Bruland Sophia Geßner Julian Varghese Stefan Hegselmann Tobias Brix Martin Dugas Michael Storck

Stud Health Technol Inform 2018 ;247:231-235

Institute of Medical Informatics, University of Münster, Germany.

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June 2018

Effects of computerized decision support system implementations on patient outcomes in inpatient care: a systematic review.

Authors:
Julian Varghese Maren Kleine Sophia Isabella Gessner Sarah Sandmann Martin Dugas

J Am Med Inform Assoc 2018 05;25(5):593-602

Institute of Medical Informatics, University of Münster, Münster, Germany.

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http://dx.doi.org/10.1093/jamia/ocx100DOI Listing
May 2018

Loss of Pax5 Exploits Sca1-BCR-ABL Susceptibility to Confer the Metabolic Shift Essential for pB-ALL.

Authors:
Alberto Martín-Lorenzo Franziska Auer Lai N Chan Idoia García-Ramírez Inés González-Herrero Guillermo Rodríguez-Hernández Christoph Bartenhagen Martin Dugas Michael Gombert Sebastian Ginzel Oscar Blanco Alberto Orfao Diego Alonso-López Javier De Las Rivas Maria B García-Cenador Francisco J García-Criado Markus Müschen Isidro Sánchez-García Arndt Borkhardt Carolina Vicente-Dueñas Julia Hauer

Cancer Res 2018 05 28;78(10):2669-2679. Epub 2018 Feb 28.

Institute of Medical Informatics, University of Muenster, Muenster, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-3262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245574PMC
May 2018

Automatic Conversion of Metadata from the Study of Health in Pomerania to ODM.

Authors:
Stefan Hegselmann Sophia Gessner Philipp Neuhaus Jörg Henke Carsten Oliver Schmidt Martin Dugas

Stud Health Technol Inform 2017 ;236:88-96

Institute of Medical Informatics, University of Münster, Germany.

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April 2018

Automated Transformation of CDISC ODM to OpenClinica.

Authors:
Sophia Gessner Michael Storck Stefan Hegselmann Martin Dugas Iñaki Soto-Rey

Stud Health Technol Inform 2017 ;243:95-99

Institute of Medical Informatics, University of Münster, Germany.

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April 2018

Validation of Pruritus Measures Gathered with the Electronic Patient-reported Outcome System MoPat.

Authors:
Michael Storck Claudia Zeidler Mirjam Rehr Claudia Riepe Martin Dugas Sonja Ständer Iñaki Soto-Rey

Acta Derm Venereol 2018 Jan;98(1):38-43

Institute of Medical Informatics, University of Münster, Domagkstrasse 9, DE-48149 Münster, Germany.

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http://dx.doi.org/10.2340/00015555-2799DOI Listing
January 2018

Genetic predisposition in children with cancer - affected families' acceptance of Trio-WES.

Authors:
Triantafyllia Brozou Julia Taeubner Eunike Velleuer Martin Dugas Dagmar Wieczorek Arndt Borkhardt Michaela Kuhlen

Eur J Pediatr 2018 Jan 19;177(1):53-60. Epub 2017 Sep 19.

Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University, Moorenstr. 5, 40225, Duesseldorf, Germany.

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http://dx.doi.org/10.1007/s00431-017-2997-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748429PMC
January 2018

Correction to: Genetic predisposition in children with cancer - affected families' acceptance of Trio-WES.

Authors:
Triantafyllia Brozou Julia Taeubner Eunike Velleuer Martin Dugas Dagmar Wieczorek Arndt Borkhardt Michaela Kuhlen

Eur J Pediatr 2018 01;177(1):61

Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University, Moorenstr. 5, 40225, Duesseldorf, Germany.

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http://dx.doi.org/10.1007/s00431-017-3033-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828017PMC
January 2018

Management of chronic pruritus: from the dermatological office to the specialized itch center: a review.

Authors:
Manuel P Pereira Sabine Steinke Philipp Bruland Hartmut F Ständer Martin Dugas Matthias Augustin Sonja Ständer

Itch (Phila) 2017 Sep 2;2(2):e6. Epub 2017 Oct 2.

Department of Dermatology and Center for Chronic Pruritus.

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http://dx.doi.org/10.1097/itx.0000000000000006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372054PMC
September 2017

GLM-based optimization of NGS data analysis: A case study of Roche 454, Ion Torrent PGM and Illumina NextSeq sequencing data.

Authors:
Sarah Sandmann Aniek O de Graaf Bert A van der Reijden Joop H Jansen Martin Dugas

PLoS One 2017 21;12(2):e0171983. Epub 2017 Feb 21.

Institute of Medical Informatics, University of Münster, Münster, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0171983PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5319672PMC
August 2017

Infection Exposure Promotes Precursor B-cell Leukemia via Impaired H3K4 Demethylases.

Authors:
Guillermo Rodríguez-Hernández Julia Hauer Alberto Martín-Lorenzo Daniel Schäfer Christoph Bartenhagen Idoia García-Ramírez Franziska Auer Inés González-Herrero Lucia Ruiz-Roca Michael Gombert Vera Okpanyi Ute Fischer Cai Chen Martin Dugas Sanil Bhatia René Martin Linka Marta Garcia-Suquia María Victoria Rascón-Trincado Angel Garcia-Sanchez Oscar Blanco Maria Begoña García-Cenador Francisco Javier García-Criado César Cobaleda Diego Alonso-López Javier De Las Rivas Markus Müschen Carolina Vicente-Dueñas Isidro Sánchez-García Arndt Borkhardt

Cancer Res 2017 08 19;77(16):4365-4377. Epub 2017 Jun 19.

Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich-Heine University Düsseldorf, Medical Faculty, Düsseldorf, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-0701DOI Listing
August 2017

Impact of Molecular Genetics on Outcome in Myelofibrosis Patients after Allogeneic Stem Cell Transplantation.

Authors:
Nicolaus Kröger Victoria Panagiota Anita Badbaran Tatjana Zabelina Ioanna Triviai Michelle Maria Araujo Cruz Rabia Shahswar Francis Ayuk Marten Gehlhaar Christine Wolschke Robin Bollin Carolin Walter Martin Dugas Lutz Wiehlmann Ulrich Lehmann Christian Koenecke Anuhar Chaturvedi Haefaa Alchalby Michael Stadler Matthias Eder Max Christopeit Gudrun Göhring Michael Koenigsmann Brigitte Schlegelberger Hans-Heinrich Kreipe Arnold Ganser Carol Stocking Boris Fehse Felicitas Thol Michael Heuser

Biol Blood Marrow Transplant 2017 Jul 4;23(7):1095-1101. Epub 2017 Apr 4.

Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1016/j.bbmt.2017.03.034DOI Listing
July 2017

AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia.

Authors:
Fengbiao Zhou Yi Liu Christian Rohde Cornelius Pauli Dennis Gerloff Marcel Köhn Danny Misiak Nicole Bäumer Chunhong Cui Stefanie Göllner Thomas Oellerich Hubert Serve Maria-Paz Garcia-Cuellar Robert Slany Jaroslaw P Maciejewski Bartlomiej Przychodzen Barbara Seliger Hans-Ulrich Klein Christoph Bartenhagen Wolfgang E Berdel Martin Dugas Makoto Mark Taketo Daneyal Farouq Schraga Schwartz Aviv Regev Josée Hébert Guy Sauvageau Caroline Pabst Stefan Hüttelmaier Carsten Müller-Tidow

Nat Cell Biol 2017 Jul 26;19(7):844-855. Epub 2017 Jun 26.

Department of Hematology and Oncology, University of Halle, Halle 06120, Germany.

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http://dx.doi.org/10.1038/ncb3563DOI Listing
July 2017

ODMSummary: A Tool for Automatic Structured Comparison of Multiple Medical Forms Based on Semantic Annotation with the Unified Medical Language System.

Authors:
Michael Storck Rainer Krumm Martin Dugas

PLoS One 2016 13;11(10):e0164569. Epub 2016 Oct 13.

Institute of Medical Informatics, University of Münster, Münster, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0164569PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063379PMC
May 2017

Infection as a cause of childhood leukemia: virus detection employing whole genome sequencing.

Authors:
Christoph Bartenhagen Ute Fischer Klaus Korn Stefan M Pfister Michael Gombert Cai Chen Vera Okpanyi Julia Hauer Anna Rinaldi Jean-Pierre Bourquin Cornelia Eckert Jianda Hu Armin Ensser Martin Dugas Arndt Borkhardt

Haematologica 2017 05 2;102(5):e179-e183. Epub 2017 Feb 2.

Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany.

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http://dx.doi.org/10.3324/haematol.2016.155382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685284PMC
May 2017

Key Data Elements in Myeloid Leukemia.

Authors:
Julian Varghese Christian Holz Phillip Neuhaus Massimo Bernardi Alexandra Boehm Arnold Ganser Steven Gore Mark Heaney Andreas Hochhaus Wolf-Karsten Hofmann Utz Krug Carsten Müller-Tidow Alexandra Smith Ansgar Weltermann Theo de Witte Rüdiger Hehlmann Martin Dugas

Stud Health Technol Inform 2016 ;228:282-6

Institute of Medical Informatics, University of Muenster, Germany.

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April 2017

Implementation of an ODM and HL7 Compliant Electronic Patient-Reported Outcome System.

Authors:
Iñaki Soto-Rey Martin Dugas Michael Storck

Stud Health Technol Inform 2016 ;228:421-5

Institute of Medical Informatics, Universtity of Münster.

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April 2017

Converting ODM Metadata to FHIR Questionnaire Resources.

Authors:
Justin Doods Philipp Neuhaus Martin Dugas

Stud Health Technol Inform 2016 ;228:456-60

Institute of Medical Informatics, University of Münster.

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April 2017

Clonal evolution in myelodysplastic syndromes.

Authors:
Pedro da Silva-Coelho Leonie I Kroeze Kenichi Yoshida Theresia N Koorenhof-Scheele Ruth Knops Louis T van de Locht Aniek O de Graaf Marion Massop Sarah Sandmann Martin Dugas Marian J Stevens-Kroef Jaroslav Cermak Yuichi Shiraishi Kenichi Chiba Hiroko Tanaka Satoru Miyano Theo de Witte Nicole M A Blijlevens Petra Muus Gerwin Huls Bert A van der Reijden Seishi Ogawa Joop H Jansen

Nat Commun 2017 04 21;8:15099. Epub 2017 Apr 21.

Laboratory of Hematology, Radboud University Medical Center, Geert Grooteplein Zuid 8, 6525 GA Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/ncomms15099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530598PMC
April 2017

Evaluating Variant Calling Tools for Non-Matched Next-Generation Sequencing Data.

Authors:
Sarah Sandmann Aniek O de Graaf Mohsen Karimi Bert A van der Reijden Eva Hellström-Lindberg Joop H Jansen Martin Dugas

Sci Rep 2017 02 24;7:43169. Epub 2017 Feb 24.

Institute of Medical Informatics, University of Münster, Münster, 48149, Germany.

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http://dx.doi.org/10.1038/srep43169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324109PMC
February 2017

BBCAnalyzer: a visual approach to facilitate variant calling.

Authors:
Sarah Sandmann Aniek O de Graaf Martin Dugas

BMC Bioinformatics 2017 Feb 28;18(1):133. Epub 2017 Feb 28.

Institute of Medical Informatics, University of Münster, Albert-Schweitzer-Campus 1, Münster, 48149, Germany.

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http://dx.doi.org/10.1186/s12859-017-1549-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330023PMC
February 2017

Leveraging the EHR4CR platform to support patient inclusion in academic studies: challenges and lessons learned.

Authors:
Yannick Girardeau Justin Doods Eric Zapletal Gilles Chatellier Christel Daniel Anita Burgun Martin Dugas Bastien Rance

BMC Med Res Methodol 2017 02 28;17(1):36. Epub 2017 Feb 28.

Biomedical Informatics and Public Health department, Hôpital Européen Georges Pompidou, AP-HP, 10 Rue Leblanc, 75015, Paris, France.

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http://dx.doi.org/10.1186/s12874-017-0299-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5329914PMC
February 2017

Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia.

Authors:
Stefanie Göllner Thomas Oellerich Shuchi Agrawal-Singh Tino Schenk Hans-Ulrich Klein Christian Rohde Caroline Pabst Tim Sauer Mads Lerdrup Sigal Tavor Friedrich Stölzel Sylvia Herold Gerhard Ehninger Gabriele Köhler Kuan-Ting Pan Henning Urlaub Hubert Serve Martin Dugas Karsten Spiekermann Binje Vick Irmela Jeremias Wolfgang E Berdel Klaus Hansen Arthur Zelent Claudia Wickenhauser Lutz P Müller Christian Thiede Carsten Müller-Tidow

Nat Med 2017 01 12;23(1):69-78. Epub 2016 Dec 12.

Department of Medicine IV, Hematology and Oncology, University Hospital of Halle (Saale), Halle (Saale), Germany.

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http://dx.doi.org/10.1038/nm.4247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548550PMC
January 2017

S2O - A software tool for integrating research data from general purpose statistic software into electronic data capture systems.

Authors:
Philipp Bruland Martin Dugas

BMC Med Inform Decis Mak 2017 01 7;17(1). Epub 2017 Jan 7.

Institute of Medical Informatics, University of Münster, 48149, Münster, Germany.

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http://dx.doi.org/10.1186/s12911-016-0402-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5219713PMC
January 2017

Clinical Trial Feasibility Study Questionnaire Analysis.

Authors:
Iñaki Soto-Rey Martin Dugas Fleur Fritz

Stud Health Technol Inform 2015 ;216:1029

Institute of Medical Informatics, University of Münster, Germany.

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December 2016

A European inventory of data elements for patient recruitment.

Authors:
Justin Doods Caroline Lafitte Nadine Ulliac-Sagnes Johan Proeve Florence Botteri Robert Walls Andy Sykes Martin Dugas Fleur Fritz

Stud Health Technol Inform 2015 ;210:506-10

Institute of Medical Informatics, University Münster, Albert-Schweitzer-Campus 1/A11, D-48149 Münster, Germany.

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November 2016

Standardized quality assurance forms for organ transplantations with multilingual support, open access and UMLS coding.

Authors:
Julian Varghese Sarah Schulze Sünninghausen Martin Dugas

Stud Health Technol Inform 2015 ;212:15-22

Institute of Medical Informatics, University of Muenster, Germany.

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November 2016

Standardized mappings--a framework to combine different semantic mappers into a standardized web-API.

Authors:
Philipp Neuhaus Justin Doods Martin Dugas

Stud Health Technol Inform 2015 ;212:23-6

Institute of Medical Informatics, Westfälische Wilhelms-Universität, Münster, Germany.

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November 2016

Web-based multi-site feasibility questionnaire tool.

Authors:
Iñaki Soto-Rey Benjamin Trinczek Jose Ignacio Amo Jesús Bauselas Martin Dugas Fleur Fritz

Stud Health Technol Inform 2015 ;212:88-93

Institute of Medical Informatics, University of Münster, Germany.

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November 2016

Myeloid leukemia with transdifferentiation plasticity developing from T-cell progenitors.

Authors:
Pia Riemke Melinda Czeh Josephine Fischer Carolin Walter Saeed Ghani Matthias Zepper Konstantin Agelopoulos Stephanie Lettermann Marie L Gebhardt Nancy Mah Andre Weilemann Michael Grau Verena Gröning Torsten Haferlach Dido Lenze Ruud Delwel Marco Prinz Miguel A Andrade-Navarro Georg Lenz Martin Dugas Carsten Müller-Tidow Frank Rosenbauer

EMBO J 2016 11 29;35(22):2399-2416. Epub 2016 Aug 29.

Institute of Molecular Tumor Biology, University of Münster, Münster, Germany

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http://dx.doi.org/10.15252/embj.201693927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109237PMC
November 2016

Common data elements for secondary use of electronic health record data for clinical trial execution and serious adverse event reporting.

Authors:
Philipp Bruland Mark McGilchrist Eric Zapletal Dionisio Acosta Johann Proeve Scott Askin Thomas Ganslandt Justin Doods Martin Dugas

BMC Med Res Methodol 2016 11 22;16(1):159. Epub 2016 Nov 22.

Institute of Medical Informatics, University of Münster, Münster, 48149, Germany.

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http://dx.doi.org/10.1186/s12874-016-0259-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5118882PMC
November 2016

Design of case report forms based on a public metadata registry: re-use of data elements to improve compatibility of data.

Authors:
Martin Dugas

Trials 2016 11 29;17(1):566. Epub 2016 Nov 29.

Institute of Medical Informatics, University of Münster, Albert-Schweitzer-Campus 1, A11, D-48149, Münster, Germany.

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http://dx.doi.org/10.1186/s13063-016-1691-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129226PMC
November 2016

Portal of medical data models: information infrastructure for medical research and healthcare.

Authors:
Martin Dugas Philipp Neuhaus Alexandra Meidt Justin Doods Michael Storck Philipp Bruland Julian Varghese

Database (Oxford) 2016 11;2016. Epub 2016 Feb 11.

Institute of Medical Informatics, University of Münster, Germany.

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http://dx.doi.org/10.1093/database/bav121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750548PMC
October 2016

Using Electronic Health Records to Support Clinical Trials: A Report on Stakeholder Engagement for EHR4CR.

Authors:
Colin McCowan Elizabeth Thomson Cezary A Szmigielski Dipak Kalra Frank M Sullivan Hans-Ulrich Prokosch Martin Dugas Ian Ford

Biomed Res Int 2015 11;2015:707891. Epub 2015 Oct 11.

Robertson Centre for Biostatistics, Institute of Health and Wellbeing, University of Glasgow, Glasgow G12 8QQ, UK.

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http://eprints.gla.ac.uk/112388/1/112388.pdf
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http://www.hindawi.com/journals/bmri/2015/707891/
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http://dx.doi.org/10.1155/2015/707891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619877PMC
August 2016

Health-Related Quality of Life in Chronic Pruritus: An Analysis Related to Disease Etiology, Clinical Skin Conditions and Itch Intensity.

Authors:
Benjamin Warlich Fleur Fritz Nani Osada Philipp Bruland Astrid Stumpf Gudrun Schneider Martin Dugas Bettina Pfleiderer Sonja Ständer

Dermatology 2015 13;231(3):253-9. Epub 2015 Aug 13.

Department of Dermatology, Center for Chronic Pruritus, University Hospital Mx00FC;nster, Mx00FC;nster, Germany.

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http://dx.doi.org/10.1159/000437206DOI Listing
June 2016

ODMedit: uniform semantic annotation for data integration in medicine based on a public metadata repository.

Authors:
Martin Dugas Alexandra Meidt Philipp Neuhaus Michael Storck Julian Varghese

BMC Med Res Methodol 2016 06 1;16:65. Epub 2016 Jun 1.

Institute of Medical Informatics, University of Münster, Albert-Schweitzer-Campus 1 | A11, D-48149, Münster, Germany.

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http://dx.doi.org/10.1186/s12874-016-0164-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888420PMC
June 2016

Sharing clinical trial data.

Authors:
Martin Dugas

Lancet 2016 Jun;387(10035):2287

Medical Informatics, University of Münster, Münster D-48149, Germany. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(16)30683-3DOI Listing
June 2016

Standardized Cardiovascular Quality Assurance Forms with Multilingual Support, UMLS Coding and Medical Concept Analyses.

Authors:
Julian Varghese Sarah Schulze Sünninghausen Martin Dugas

Stud Health Technol Inform 2015 ;216:837-41

Institute of Medical Informatics, University of Muenster, Germany.

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April 2016

[Leukemia research in Germany: the Competence Network Acute and Chronic Leukemias].

Authors:
Ute Kossak-Roth Susanne Saußele Carlo Aul Thomas Büchner Hartmut Döhner Martin Dugas Gerhard Ehninger Arnold Ganser Aristoteles Giagounidis Nicola Gökbuget Martin Griesshammer Jörg Hasford Michael Heuser Wolfgang Hiddemann Andreas Hochhaus Dieter Hoelzer Dietger Niederwieser Andreas Reiter Christoph Röllig Rüdiger Hehlmann

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2016 Apr;59(4):444-53

Medizinische Fakultät Mannheim der Universität Heidelberg, Pettenkoferstr. 22, 68169, Mannheim, Deutschland.

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http://dx.doi.org/10.1007/s00103-016-2315-xDOI Listing
April 2016

Leukemogenic MLL-ENL Fusions Induce Alternative Chromatin States to Drive a Functionally Dichotomous Group of Target Genes.

Authors:
Maria-Paz Garcia-Cuellar Christian Büttner Christoph Bartenhagen Martin Dugas Robert K Slany

Cell Rep 2016 Apr 31;15(2):310-22. Epub 2016 Mar 31.

Department of Genetics, Friedrich-Alexander-University Erlangen-Nürnberg, 91058 Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.03.018DOI Listing
April 2016

Increased DNA methylation of Dnmt3b targets impairs leukemogenesis.

Authors:
Isabell Schulze Christian Rohde Marina Scheller-Wendorff Nicole Bäumer Annika Krause Friederike Herbst Pia Riemke Katja Hebestreit Petra Tschanter Qiong Lin Heinz Linhart Lucy A Godley Hanno Glimm Martin Dugas Wolfgang Wagner Wolfgang E Berdel Frank Rosenbauer Carsten Müller-Tidow

Blood 2016 Mar 4;127(12):1575-86. Epub 2016 Jan 4.

Department of Hematology and Oncology, University of Halle, Halle, Germany;

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http://dx.doi.org/10.1182/blood-2015-07-655928DOI Listing
March 2016

Identification of the Adapter Molecule MTSS1 as a Potential Oncogene-Specific Tumor Suppressor in Acute Myeloid Leukemia.

Authors:
Mirle Schemionek Behzad Kharabi Masouleh Yvonne Klaile Utz Krug Katja Hebestreit Claudia Schubert Martin Dugas Thomas Büchner Bernhard Wörmann Wolfgang Hiddemann Wolfgang E Berdel Tim H Brümmendorf Carsten Müller-Tidow Steffen Koschmieder

PLoS One 2015 21;10(5):e0125783. Epub 2015 May 21.

Department of Hematology, Oncology, Hemostaseology, and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0125783PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440712PMC
February 2016

Robust and exact structural variation detection with paired-end and soft-clipped alignments: SoftSV compared with eight algorithms.

Authors:
Christoph Bartenhagen Martin Dugas

Brief Bioinform 2016 Jan 20;17(1):51-62. Epub 2015 May 20.

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https://academic.oup.com/bib/article-lookup/doi/10.1093/bib/
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http://dx.doi.org/10.1093/bib/bbv028DOI Listing
January 2016

Infection Exposure is a Causal Factor in B-cell Precursor Acute Lymphoblastic Leukemia as a Result of Pax5-Inherited Susceptibility.

Authors:
Alberto Martín-Lorenzo Julia Hauer Carolina Vicente-Dueñas Franziska Auer Inés González-Herrero Idoia García-Ramírez Sebastian Ginzel Ralf Thiele Stefan N Constantinescu Christoph Bartenhagen Martin Dugas Michael Gombert Daniel Schäfer Oscar Blanco Andrea Mayado Alberto Orfao Diego Alonso-López Javier De Las Rivas César Cobaleda Maria Begoña García-Cenador Francisco Javier García-Criado Isidro Sánchez-García Arndt Borkhardt

Cancer Discov 2015 Dec 25;5(12):1328-43. Epub 2015 Sep 25.

Department of Pediatric Oncology, Hematology and Clinical Immunology, Heinrich-Heine University Dusseldorf, Medical Faculty, Dusseldorf, Germany.

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http://dx.doi.org/10.1158/2159-8290.CD-15-0892DOI Listing
December 2015

Genomic landscape of liposarcoma.

Authors:
Deepika Kanojia Yasunobu Nagata Manoj Garg Dhong Hyun Lee Aiko Sato Kenichi Yoshida Yusuke Sato Masashi Sanada Anand Mayakonda Christoph Bartenhagen Hans-Ulrich Klein Ngan B Doan Jonathan W Said S Mohith Swetha Gunasekar Yuichi Shiraishi Kenichi Chiba Hiroko Tanaka Satoru Miyano Ola Myklebost Henry Yang Martin Dugas Leonardo A Meza-Zepeda Allan W Silberman Charles Forscher Jeffrey W Tyner Seishi Ogawa H Phillip Koeffler

Oncotarget 2015 Dec;6(40):42429-44

Cancer Science Institute of Singapore, National University of Singapore, Singapore.

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http://dx.doi.org/10.18632/oncotarget.6464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767443PMC
December 2015

Deep Sequencing in Conjunction with Expression and Functional Analyses Reveals Activation of FGFR1 in Ewing Sarcoma.

Authors:
Konstantin Agelopoulos Günther H S Richter Eva Schmidt Uta Dirksen Kristina von Heyking Benjamin Moser Hans-Ulrich Klein Udo Kontny Martin Dugas Kathrin Poos Eberhard Korsching Thorsten Buch Matthias Weckesser Isabell Schulze Regina Besoke Anika Witten Monika Stoll Gabriele Köhler Wolfgang Hartmann Eva Wardelmann Claudia Rossig Daniel Baumhoer Heribert Jürgens Stefan Burdach Wolfgang E Berdel Carsten Müller-Tidow

Clin Cancer Res 2015 Nov 15;21(21):4935-46. Epub 2015 Jul 15.

Department of Medicine A, Hematology, and Oncology, University Hospital of Muenster, Muenster, Germany. Department of Medicine IV, Hematology and Oncology, State Center for Cell and Gene Therapy, University Hospital Halle, Halle (Saale), Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2744DOI Listing
November 2015

Epigenetic dysregulation of KCa 3.1 channels induces poor prognosis in lung cancer.

Authors:
Etmar Bulk Anne-Sophie Ay Mehdi Hammadi Halima Ouadid-Ahidouch Sonja Schelhaas Antje Hascher Christian Rohde Nils H Thoennissen Rainer Wiewrodt Eva Schmidt Alessandro Marra Ludger Hillejan Andreas H Jacobs Hans-Ulrich Klein Martin Dugas Wolfgang E Berdel Carsten Müller-Tidow Albrecht Schwab

Int J Cancer 2015 Sep 29;137(6):1306-17. Epub 2015 May 29.

Institute of Physiology II, University of Münster, Münster, Germany.

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http://dx.doi.org/10.1002/ijc.29490DOI Listing
September 2015

MYST2 acetyltransferase expression and Histone H4 Lysine acetylation are suppressed in AML.

Authors:
Tim Sauer Maria Francisca Arteaga Fabienne Isken Christian Rohde Katja Hebestreit Jan-Henrik Mikesch Matthias Stelljes Chunhong Cui Fengbiao Zhou Stefanie Göllner Nicole Bäumer Gabriele Köhler Utz Krug Christian Thiede Gerhard Ehninger Bayram Edemir Peter Schlenke Wolfgang E Berdel Martin Dugas Carsten Müller-Tidow

Exp Hematol 2015 Sep 11;43(9):794-802.e4. Epub 2015 Jun 11.

Department of Medicine A, Hematology, Hemostaseology, Oncology and Pneumology, University of Muenster, Muenster, Germany; Department of Medicine, Hematology and Oncology, University of Halle, Halle, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2015.05.010DOI Listing
September 2015

Next-generation-sequencing of recurrent childhood high hyperdiploid acute lymphoblastic leukemia reveals mutations typically associated with high risk patients.

Authors:
Cai Chen Christoph Bartenhagen Michael Gombert Vera Okpanyi Vera Binder Silja Röttgers Jutta Bradtke Andrea Teigler-Schlegel Jochen Harbott Sebastian Ginzel Ralf Thiele Peter Husemann Pina F I Krell Arndt Borkhardt Martin Dugas Jianda Hu Ute Fischer

Leuk Res 2015 Sep 14;39(9):990-1001. Epub 2015 Jun 14.

Department of Pediatric Oncology, Hematology and Clinical Immunology, University Children's Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2015.06.005DOI Listing
September 2015

BRCC3 mutations in myeloid neoplasms.

Authors:
Dayong Huang Yasunobu Nagata Vera Grossmann Tomas Radivoyevitch Yusuke Okuno Genta Nagae Naoko Hosono Susanne Schnittger Masashi Sanada Bartlomiej Przychodzen Ayana Kon Chantana Polprasert Wenyi Shen Michael J Clemente James G Phillips Tamara Alpermann Kenichi Yoshida Niroshan Nadarajah Mikkael A Sekeres Kevin Oakley Nhu Nguyen Yuichi Shiraishi Yusuke Shiozawa Kenichi Chiba Hiroko Tanaka H Phillip Koeffler Hans-Ulrich Klein Martin Dugas Hiroyuki Aburatani Satoru Miyano Claudia Haferlach Wolfgang Kern Torsten Haferlach Yang Du Seishi Ogawa Hideki Makishima

Haematologica 2015 Aug 22;100(8):1051-7. Epub 2015 May 22.

Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA Department of Pathology and Tumor Biology, Kyoto University, Japan

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http://dx.doi.org/10.3324/haematol.2014.111989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004421PMC
August 2015

Towards a trial-ready mobile patient questionnaire system.

Authors:
Michael Storck Benjamin Trinczek Martin Dugas Fleur Fritz

Stud Health Technol Inform 2014 ;205:768-72

Institute of Medical Informatics, University of Münster, Münster, Germany.

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May 2015

Analysis of eligibility criteria from ClinicalTrials.gov.

Authors:
Justin Doods Martin Dugas Fleur Fritz

Stud Health Technol Inform 2014 ;205:853-7

Insitute of Medical Informatics, University of Münster, Germany.

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May 2015

Protocol feasibility workflow using an automated multi-country patient cohort system.

Authors:
Iñaki Soto-Rey Benjamin Trinczek Töresin Karakoyun Martin Dugas Fleur Fritz

Stud Health Technol Inform 2014 ;205:985-9

Institute of Medical Informatics, University of Münster, Germany.

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May 2015

Inherited and Somatic Defects in DDX41 in Myeloid Neoplasms.

Authors:
Chantana Polprasert Isabell Schulze Mikkael A Sekeres Hideki Makishima Bartlomiej Przychodzen Naoko Hosono Jarnail Singh Richard A Padgett Xiaorong Gu James G Phillips Michael Clemente Yvonne Parker Daniel Lindner Brittney Dienes Eckhard Jankowsky Yogen Saunthararajah Yang Du Kevin Oakley Nhu Nguyen Sudipto Mukherjee Caroline Pabst Lucy A Godley Jane E Churpek Daniel A Pollyea Utz Krug Wolfgang E Berdel Hans-Ulrich Klein Martin Dugas Yuichi Shiraishi Kenichi Chiba Hiroko Tanaka Satoru Miyano Kenichi Yoshida Seishi Ogawa Carsten Müller-Tidow Jaroslaw P Maciejewski

Cancer Cell 2015 May 23;27(5):658-70. Epub 2015 Apr 23.

Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland, OH 44195, USA; Leukemia Program, Cleveland Clinic, Taussig Cancer Institute, Cleveland, OH 44195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2015.03.017DOI Listing
May 2015

Efficiency and effectiveness evaluation of an automated multi-country patient count cohort system.

Authors:
Iñaki Soto-Rey Benjamin Trinczek Yannick Girardeau Eric Zapletal Nadir Ammour Justin Doods Martin Dugas Fleur Fritz

BMC Med Res Methodol 2015 May 1;15:44. Epub 2015 May 1.

Institute of Medical Informatics, University of Münster, Albert-Schweitzer-Campus 1/A11, D-48149, Münster, Germany.

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http://dx.doi.org/10.1186/s12874-015-0035-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423123PMC
May 2015

ODM2CDA and CDA2ODM: tools to convert documentation forms between EDC and EHR systems.

Authors:
Martin Dugas

BMC Med Inform Decis Mak 2015 May 26;15:40. Epub 2015 May 26.

Institute of Medical Informatics, University of Münster, Albert-Schweitzer-Campus 1, A11, D-48149, Münster, Germany.

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http://dx.doi.org/10.1186/s12911-015-0163-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494189PMC
May 2015

Facing the challenges of chronic pruritus: a report from a multi-disciplinary medical itch centre in Germany.

Authors:
Sonja Ständer Esther Pogatzki-Zahn Astrid Stumpf Fleur Fritz Bettina Pfleiderer Anika Ritzkat Philipp Bruland Tobias Lotts Carsten Müller-Tidow Gereon Heuft Hermann-Joseph Pavenstädt Gudrun Schneider Hugo Van Aken Walter Heindel Heinz Wiendl Martin Dugas Thomas A Luger

Acta Derm Venereol 2015 Mar;95(3):266-71

Department of Dermatology, Competence Center Chronic Pruritus, University Hospital of Münster, Von-Esmarch-Str. 58, DE-48149 Münster, Germany.

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http://dx.doi.org/10.2340/00015555-1949DOI Listing
March 2015

Success criteria for electronic medical record implementations in low-resource settings: a systematic review.

Authors:
Fleur Fritz Binyam Tilahun Martin Dugas

J Am Med Inform Assoc 2015 Mar 13;22(2):479-88. Epub 2015 Mar 13.

Institute of Medical Informatics, University of Münster, Münster, Germany.

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http://dx.doi.org/10.1093/jamia/ocu038DOI Listing
March 2015

Using electronic health records for clinical research: the case of the EHR4CR project.

Authors:
Georges De Moor Mats Sundgren Dipak Kalra Andreas Schmidt Martin Dugas Brecht Claerhout Töresin Karakoyun Christian Ohmann Pierre-Yves Lastic Nadir Ammour Rebecca Kush Danielle Dupont Marc Cuggia Christel Daniel Geert Thienpont Pascal Coorevits

J Biomed Inform 2015 Feb 18;53:162-73. Epub 2014 Oct 18.

Department of Public Health, Unit of Medical Informatics and Statistics, Ghent University, Ghent, Belgium; The European Institute for Health Records (EuroRec), Sint-Martens-Latem, Belgium. Electronic address:

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http://www.ehr4cr.eu/files/publications/Corevits_et_al_Journ
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http://linkinghub.elsevier.com/retrieve/pii/S153204641400226
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http://dx.doi.org/10.1016/j.jbi.2014.10.006DOI Listing
February 2015

Does single-source create an added value? Evaluating the impact of introducing x4T into the clinical routine on workflow modifications, data quality and cost-benefit.

Authors:
Philipp Bruland Christian Forster Bernhard Breil Sonja Ständer Martin Dugas Fleur Fritz

Int J Med Inform 2014 Dec 29;83(12):915-28. Epub 2014 Aug 29.

Institute of Medical Informatics, University of Münster, Germany.

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http://dx.doi.org/10.1016/j.ijmedinf.2014.08.007DOI Listing
December 2014

Basic4Cseq: an R/Bioconductor package for analyzing 4C-seq data.

Authors:
Carolin Walter Daniel Schuetzmann Frank Rosenbauer Martin Dugas

Bioinformatics 2014 Nov 30;30(22):3268-9. Epub 2014 Jul 30.

Institute of Medical Informatics, University of Münster, 48149 Münster, Germany, and Institute of Molecular Tumorbiology, University of Münster, 48149 Münster, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btu497DOI Listing
November 2014

Comparison of electronic health record system functionalities to support the patient recruitment process in clinical trials.

Authors:
Björn Schreiweis Benjamin Trinczek Felix Köpcke Thomas Leusch Raphael W Majeed Joachim Wenk Björn Bergh Christian Ohmann Rainer Röhrig Martin Dugas Hans-Ulrich Prokosch

Int J Med Inform 2014 Nov 25;83(11):860-8. Epub 2014 Aug 25.

Chair of Medical Informatics, Friedrich-Alexander-University Erlangen-Nuremberg, Krankenhausstraße 12, 91054 Erlangen, Germany.

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http://dx.doi.org/10.1016/j.ijmedinf.2014.08.005DOI Listing
November 2014

Characterization of image transfer patterns in a regional trauma network.

Authors:
Philipp Neuhaus Thomas Weber Martin Dugas Christian Juhra Bernhard Breil

J Med Syst 2014 Nov 30;38(11):137. Epub 2014 Sep 30.

Institut of Medical Informatics, University of Muenster, Muenster, Germany,

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http://link.springer.com/content/pdf/10.1007/s10916-014-0137
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http://link.springer.com/10.1007/s10916-014-0137-7
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http://dx.doi.org/10.1007/s10916-014-0137-7DOI Listing
November 2014

A new workflow for whole-genome sequencing of single human cells.

Authors:
Vera Binder Christoph Bartenhagen Vera Okpanyi Michael Gombert Birte Moehlendick Bianca Behrens Hans-Ulrich Klein Harald Rieder Pina Fanny Ida Krell Martin Dugas Nikolas Hendrik Stoecklein Arndt Borkhardt

Hum Mutat 2014 Oct 18;35(10):1260-70. Epub 2014 Aug 18.

Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, University of Duesseldorf, Duesseldorf, Germany.

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http://dx.doi.org/10.1002/humu.22625DOI Listing
October 2014