Publications by authors named "Martin Carroll"

99Publications

Single-cell mutation analysis of clonal evolution in myeloid malignancies.

Authors:
Linde A Miles Robert L Bowman Tiffany R Merlinsky Isabelle S Csete Aik T Ooi Robert Durruthy-Durruthy Michael Bowman Christopher Famulare Minal A Patel Pedro Mendez Chrysanthi Ainali Benjamin Demaree Cyrille L Delley Adam R Abate Manimozhi Manivannan Sombeet Sahu Aaron D Goldberg Kelly L Bolton Ahmet Zehir Raajit Rampal Martin P Carroll Sara E Meyer Aaron D Viny Ross L Levine

Nature 2020 Nov 28;587(7834):477-482. Epub 2020 Oct 28.

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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November 2020

Targeted detection and quantitation of histone modifications from 1,000 cells.

Authors:
Nebiyu A Abshiru Jacek W Sikora Jeannie M Camarillo Juliette A Morris Philip D Compton Tak Lee Yaseswini Neelamraju Samuel Haddox Caroline Sheridan Martin Carroll Larry D Cripe Martin S Tallman Elisabeth M Paietta Ari M Melnick Paul M Thomas Francine E Garrett-Bakelman Neil L Kelleher

PLoS One 2020 26;15(10):e0240829. Epub 2020 Oct 26.

Departments of Chemistry, Molecular Biosciences, and the Proteomics Center of Excellence, Northwestern University, Evanston, IL, United States of America.

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December 2020

BCL6 maintains survival and self-renewal of primary human acute myeloid leukemia cells.

Authors:
Kimihito Cojin Kawabata Hongliang Zong Cem Meydan Sarah Wyman Bas J Wouters Mayumi Sugita Srinjoy Goswami Michael Albert Winnie Yip Gail J Roboz Zhengming Chen Ruud Delwel Martin P Carroll Christopher Mason Ari Melnick Monica L Guzman

Blood 2020 Sep 10. Epub 2020 Sep 10.

Weill Medical College of Cornell University, New York, New York, United States.

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September 2020

A common protein target for an uncommon subtype of AML.

Authors:
Martin Carroll

Blood 2020 Jul;136(4):377-378

University of Pennsylvania.

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July 2020

Targeting Bim via a lncRNA Morrbid Regulates the Survival of Preleukemic and Leukemic Cells.

Authors:
Zhigang Cai Fabiola Aguilera Baskar Ramdas Swapna Vidhur Daulatabad Rajneesh Srivastava Jonathan J Kotzin Martin Carroll Gerald Wertheim Adam Williams Sarath Chandra Janga Chi Zhang Jorge Henao-Mejia Reuben Kapur

Cell Rep 2020 06;31(12):107816

Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, USA. Electronic address:

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June 2020

Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers.

Authors:
Alexandre Fagnan Frederik Otzen Bagger Maria-Riera Piqué-Borràs Cathy Ignacimouttou Alexis Caulier Cécile K Lopez Elie Robert Benjamin Uzan Véronique Gelsi-Boyer Zakia Aid Cécile Thirant Ute Moll Samantha Tauchmann Amina Kurtovic-Kozaric Jaroslaw Maciejewski Christine Dierks Orietta Spinelli Silvia Salmoiraghi Thomas Pabst Kazuya Shimoda Virginie Deleuze Hélène Lapillonne Connor Sweeney Véronique De Mas Betty Leite Zahra Kadri Sébastien Malinge Stéphane de Botton Jean-Baptiste Micol Benjamin Kile Catherine L Carmichael Ilaria Iacobucci Charles G Mullighan Martin Carroll Peter Valent Olivier A Bernard Eric Delabesse Paresh Vyas Daniel Birnbaum Eduardo Anguita Loïc Garçon Eric Soler Juerg Schwaller Thomas Mercher

Blood 2020 Aug;136(6):698-714

Unité 1170 (U1170), INSERM, Gustave Roussy, Université Paris Diderot, Villejuif, France.

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August 2020

Oncogene-independent BCR-like signaling adaptation confers drug resistance in Ph-like ALL.

Authors:
Christian Hurtz Gerald B Wertheim Joseph P Loftus Daniel Blumenthal Anne Lehman Yong Li Asen Bagashev Bryan Manning Katherine D Cummins Janis K Burkhardt Alexander E Perl Martin Carroll Sarah K Tasian

J Clin Invest 2020 Jul;130(7):3637-3653

Division of Oncology, and.

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July 2020

Gilteritinib induces differentiation in relapsed and refractory -mutated acute myeloid leukemia.

Authors:
Christine M McMahon Jonathan Canaani Bryan Rea Rachel L Sargent Julianne N Qualtieri Christopher D Watt Jennifer J D Morrissette Martin Carroll Alexander E Perl

Blood Adv 2019 05;3(10):1581-1585

Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA.

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May 2019

Clonal Selection with RAS Pathway Activation Mediates Secondary Clinical Resistance to Selective FLT3 Inhibition in Acute Myeloid Leukemia.

Authors:
Christine M McMahon Timothy Ferng Jonathan Canaani Eunice S Wang Jennifer J D Morrissette Dennis J Eastburn Maurizio Pellegrino Robert Durruthy-Durruthy Christopher D Watt Saurabh Asthana Elisabeth A Lasater RosaAnna DeFilippis Cheryl A C Peretz Lisa H F McGary Safoora Deihimi Aaron C Logan Selina M Luger Neil P Shah Martin Carroll Catherine C Smith Alexander E Perl

Cancer Discov 2019 08 14;9(8):1050-1063. Epub 2019 May 14.

Division of Hematology-Oncology, University of Pennsylvania, Philadelphia, Pennsylvania.

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August 2019

Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML.

Authors:
Cihangir Duy Matt Teater Francine E Garrett-Bakelman Tak C Lee Cem Meydan Jacob L Glass Meng Li Johannes C Hellmuth Helai P Mohammad Kimberly N Smitheman Alan H Shih Omar Abdel-Wahab Martin S Tallman Monica L Guzman David Muench H Leighton Grimes Gail J Roboz Ryan G Kruger Caretha L Creasy Elisabeth M Paietta Ross L Levine Martin Carroll Ari M Melnick

Cancer Discov 2019 07 10;9(7):872-889. Epub 2019 May 10.

Department of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, New York.

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July 2019

Hematopoietic cytokines mediate resistance to targeted therapy in FLT3-ITD acute myeloid leukemia.

Authors:
Pamela J Sung Mayumi Sugita Holly Koblish Alexander E Perl Martin Carroll

Blood Adv 2019 04;3(7):1061-1072

Division of Hematology/Oncology, University of Pennsylvania, Philadelphia, PA; and.

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April 2019

Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma.

Authors:
Alfred L Garfall Edward A Stadtmauer Wei-Ting Hwang Simon F Lacey Jan Joseph Melenhorst Maria Krevvata Martin P Carroll William H Matsui Qiuju Wang Madhav V Dhodapkar Kavita Dhodapkar Rituparna Das Dan T Vogl Brendan M Weiss Adam D Cohen Patricia A Mangan Emily C Ayers Selene Nunez-Cruz Irina Kulikovskaya Megan M Davis Anne Lamontagne Karen Dengel Naseem Ds Kerr Regina M Young Donald L Siegel Bruce L Levine Michael C Milone Marcela V Maus Carl H June

JCI Insight 2019 02 21;4(4). Epub 2019 Feb 21.

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February 2019

Aberrant splicing in B-cell acute lymphoblastic leukemia.

Authors:
Kathryn L Black Ammar S Naqvi Mukta Asnani Katharina E Hayer Scarlett Y Yang Elisabeth Gillespie Asen Bagashev Vinodh Pillai Sarah K Tasian Matthew R Gazzara Martin Carroll Deanne Taylor Kristen W Lynch Yoseph Barash Andrei Thomas-Tikhonenko

Nucleic Acids Res 2019 01;47(2):1043

Department of Pathology, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

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January 2019

Targeting EIF4E signaling with ribavirin in infant acute lymphoblastic leukemia.

Authors:
Karen A Urtishak Li-San Wang Biljana Culjkovic-Kraljacic James W Davenport Patrizia Porazzi Tiffaney L Vincent David T Teachey Sarah K Tasian Jonni S Moore Alix E Seif Shenghao Jin Jeffrey S Barrett Blaine W Robinson I-Ming L Chen Richard C Harvey Martin P Carroll Andrew J Carroll Nyla A Heerema Meenakshi Devidas ZoAnn E Dreyer Joanne M Hilden Stephen P Hunger Cheryl L Willman Katherine L B Borden Carolyn A Felix

Oncogene 2019 03 26;38(13):2241-2262. Epub 2018 Nov 26.

Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

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March 2019

A randomized trial of three novel regimens for recurrent acute myeloid leukemia demonstrates the continuing challenge of treating this difficult disease.

Authors:
Mark R Litzow Xin V Wang Martin P Carroll Judith E Karp Rhett P Ketterling Yanming Zhang Scott H Kaufmann Hillard M Lazarus Selina M Luger Elisabeth M Paietta Keith W Pratz Han Win Tun Jessica K Altman Edward R Broun Witold B Rybka Jacob M Rowe Martin S Tallman

Am J Hematol 2019 01 15;94(1):111-117. Epub 2018 Nov 15.

Hematology/Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.

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January 2019

Aberrant splicing in B-cell acute lymphoblastic leukemia.

Authors:
Kathryn L Black Ammar S Naqvi Mukta Asnani Katharina E Hayer Scarlett Y Yang Elisabeth Gillespie Asen Bagashev Vinodh Pillai Sarah K Tasian Matthew R Gazzara Martin Carroll Deanne Taylor Kristen W Lynch Yoseph Barash Andrei Thomas-Tikhonenko

Nucleic Acids Res 2018 11;46(21):11357-11369

Department of Pathology, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

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November 2018

Classes of ITD Predict Outcomes in AML Patients Treated with FLT3 Inhibitors.

Authors:
Gregory W Schwartz Bryan Manning Yeqiao Zhou Priya Velu Ashkan Bigdeli Rachel Astles Anne W Lehman Jennifer J D Morrissette Alexander E Perl Mingyao Li Martin Carroll Robert B Faryabi

Clin Cancer Res 2019 01 4;25(2):573-583. Epub 2018 Sep 4.

Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

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January 2019

Targeted Enhancer Activation by a Subunit of the Integrator Complex.

Authors:
Elisa Barbieri Marco Trizzino Sarah Ann Welsh Tori Alexandra Owens Bruno Calabretta Martin Carroll Kavitha Sarma Alessandro Gardini

Mol Cell 2018 07 28;71(1):103-116.e7. Epub 2018 Jun 28.

The Wistar Institute, Gene Expression and Regulation Program, 3601 Spruce Street, Philadelphia, PA 19104, USA. Electronic address:

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July 2018

Anti-CD19 CAR T cells with high-dose melphalan and autologous stem cell transplantation for refractory multiple myeloma.

Authors:
Alfred L Garfall Edward A Stadtmauer Wei-Ting Hwang Simon F Lacey Jan Joseph Melenhorst Maria Krevvata Martin P Carroll William H Matsui Qiuju Wang Madhav V Dhodapkar Kavita Dhodapkar Rituparna Das Dan T Vogl Brendan M Weiss Adam D Cohen Patricia A Mangan Emily C Ayers Selene Nunez-Cruz Irina Kulikovskaya Megan M Davis Anne Lamontagne Karen Dengel Naseem Ds Kerr Regina M Young Donald L Siegel Bruce L Levine Michael C Milone Marcela V Maus Carl H June

JCI Insight 2018 04 19;3(8). Epub 2018 Apr 19.

Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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April 2018

Sirolimus enhances remission induction in patients with high risk acute myeloid leukemia and mTORC1 target inhibition.

Authors:
Margaret T Kasner Rosemarie Mick Grace R Jeschke Matthew Carabasi Joanne Filicko-O'Hara Neal Flomenberg Noelle V Frey Elizabeth O Hexner Selina M Luger Alison W Loren James K Mangan John L Wagner Mark Weiss Martin Carroll Alexander E Perl

Invest New Drugs 2018 08 2;36(4):657-666. Epub 2018 Apr 2.

Division of Hematology-Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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August 2018