Martin A Kennedy

Martin A Kennedy

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Martin A Kennedy

Martin A Kennedy

Publications by authors named "Martin A Kennedy"

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Pharmacogenetics of angiotensin-converting enzyme inhibitor-induced angioedema.

Clin Exp Allergy 2019 Feb 8;49(2):142-154. Epub 2019 Jan 8.

Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1111/cea.13326DOI Listing
February 2019

Gene expression effects of lithium and valproic acid in a serotonergic cell line.

Physiol Genomics 2019 Feb 21;51(2):43-50. Epub 2018 Dec 21.

Carney Centre for Pharmacogenomics, Department of Pathology and Biomedical Science, University of Otago , Christchurch , New Zealand.

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http://dx.doi.org/10.1152/physiolgenomics.00069.2018DOI Listing
February 2019

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.

Authors:
Raymond K Walters Renato Polimanti Emma C Johnson Jeanette N McClintick Mark J Adams Amy E Adkins Fazil Aliev Silviu-Alin Bacanu Anthony Batzler Sarah Bertelsen Joanna M Biernacka Tim B Bigdeli Li-Shiun Chen Toni-Kim Clarke Yi-Ling Chou Franziska Degenhardt Anna R Docherty Alexis C Edwards Pierre Fontanillas Jerome C Foo Louis Fox Josef Frank Ina Giegling Scott Gordon Laura M Hack Annette M Hartmann Sarah M Hartz Stefanie Heilmann-Heimbach Stefan Herms Colin Hodgkinson Per Hoffmann Jouke Jan Hottenga Martin A Kennedy Mervi Alanne-Kinnunen Bettina Konte Jari Lahti Marius Lahti-Pulkkinen Dongbing Lai Lannie Ligthart Anu Loukola Brion S Maher Hamdi Mbarek Andrew M McIntosh Matthew B McQueen Jacquelyn L Meyers Yuri Milaneschi Teemu Palviainen John F Pearson Roseann E Peterson Samuli Ripatti Euijung Ryu Nancy L Saccone Jessica E Salvatore Sandra Sanchez-Roige Melanie Schwandt Richard Sherva Fabian Streit Jana Strohmaier Nathaniel Thomas Jen-Chyong Wang Bradley T Webb Robbee Wedow Leah Wetherill Amanda G Wills Jason D Boardman Danfeng Chen Doo-Sup Choi William E Copeland Robert C Culverhouse Norbert Dahmen Louisa Degenhardt Benjamin W Domingue Sarah L Elson Mark A Frye Wolfgang Gäbel Caroline Hayward Marcus Ising Margaret Keyes Falk Kiefer John Kramer Samuel Kuperman Susanne Lucae Michael T Lynskey Wolfgang Maier Karl Mann Satu Männistö Bertram Müller-Myhsok Alison D Murray John I Nurnberger Aarno Palotie Ulrich Preuss Katri Räikkönen Maureen D Reynolds Monika Ridinger Norbert Scherbaum Marc A Schuckit Michael Soyka Jens Treutlein Stephanie Witt Norbert Wodarz Peter Zill Daniel E Adkins Joseph M Boden Dorret I Boomsma Laura J Bierut Sandra A Brown Kathleen K Bucholz Sven Cichon E Jane Costello Harriet de Wit Nancy Diazgranados Danielle M Dick Johan G Eriksson Lindsay A Farrer Tatiana M Foroud Nathan A Gillespie Alison M Goate David Goldman Richard A Grucza Dana B Hancock Kathleen Mullan Harris Andrew C Heath Victor Hesselbrock John K Hewitt Christian J Hopfer John Horwood William Iacono Eric O Johnson Jaakko A Kaprio Victor M Karpyak Kenneth S Kendler Henry R Kranzler Kenneth Krauter Paul Lichtenstein Penelope A Lind Matt McGue James MacKillop Pamela A F Madden Hermine H Maes Patrik Magnusson Nicholas G Martin Sarah E Medland Grant W Montgomery Elliot C Nelson Markus M Nöthen Abraham A Palmer Nancy L Pedersen Brenda W J H Penninx Bernice Porjesz John P Rice Marcella Rietschel Brien P Riley Richard Rose Dan Rujescu Pei-Hong Shen Judy Silberg Michael C Stallings Ralph E Tarter Michael M Vanyukov Scott Vrieze Tamara L Wall John B Whitfield Hongyu Zhao Benjamin M Neale Joel Gelernter Howard J Edenberg Arpana Agrawal

Nat Neurosci 2018 12 26;21(12):1656-1669. Epub 2018 Nov 26.

Washington University School of Medicine, Department of Psychiatry, St. Louis, MO, USA.

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http://dx.doi.org/10.1038/s41593-018-0275-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430207PMC
December 2018

Epigenetics, nutrition and mental health. Is there a relationship?

Nutr Neurosci 2018 Nov 29;21(9):602-613. Epub 2017 May 29.

a Department of Pathology , University of Otago , P.O. Box 4345, Christchurch , New Zealand.

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https://www.tandfonline.com/doi/full/10.1080/1028415X.2017.1
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http://dx.doi.org/10.1080/1028415X.2017.1331524DOI Listing
November 2018

Methylomic changes in response to micronutrient supplementation and MTHFR genotype.

Epigenomics 2018 09 5;10(9):1201-1214. Epub 2018 Sep 5.

Department of Pathology and Biomedical Science, University of Otago, Christchurch, P.O. Box 4345, Christchurch, New Zealand.

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http://dx.doi.org/10.2217/epi-2018-0029DOI Listing
September 2018

Testicular Cancer in New Zealand (TCNZ) study: protocol for a national case-control study.

BMJ Open 2018 08 5;8(8):e025212. Epub 2018 Aug 5.

Cancer and Chronic Conditions (C3) Research Group, Department of Public Health, University of Otago, Wellington, New Zealand.

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http://dx.doi.org/10.1136/bmjopen-2018-025212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078234PMC
August 2018

A genome project for Māori and Pasifika: charting a path to equity in genomic medicine for Aotearoa.

Authors:
Martin A Kennedy

N Z Med J 2018 08 17;131(1480):8-10. Epub 2018 Aug 17.

PhD, Research Professor and Head of Department, Pathology and Biomedical Science, University of Otago, Christchurch.

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August 2018

Multiplexed Nanopore Sequencing of HLA-B Locus in Māori and Pacific Island Samples.

Front Genet 2018 30;9:152. Epub 2018 Apr 30.

Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.3389/fgene.2018.00152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936980PMC
April 2018

Long Fragment Polymerase Chain Reaction.

Methods Mol Biol 2017 ;1620:65-74

Department of Pathology and Carney Centre for Pharmacogenomics, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1007/978-1-4939-7060-5_3DOI Listing
February 2018

A New Zealand platform to enable genetic investigation of adverse drug reactions.

N Z Med J 2017 Dec 1;130(1466):62-69. Epub 2017 Dec 1.

Department of Pathology, University of Otago, Christchurch.

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December 2017

Structural Analysis of G-Quadruplex Formation at the Human MEST Promoter.

PLoS One 2017 4;12(1):e0169433. Epub 2017 Jan 4.

Department of Pathology, School of Medicine, University of Otago, Christchurch, New Zealand.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0169433PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214457PMC
August 2017

Methylated Cytosine Maintains G-Quadruplex Structures during Polymerase Chain Reaction and Contributes to Allelic Dropout.

Biochemistry 2017 07 10;56(29):3691-3698. Epub 2017 Jul 10.

Department of Pathology, University of Otago , Christchurch, New Zealand.

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http://dx.doi.org/10.1021/acs.biochem.7b00480DOI Listing
July 2017

Effect of 7,8-dihydroneopterin mediated CD36 down regulation and oxidant scavenging on oxidised low-density lipoprotein induced cell death in human macrophages.

Int J Biochem Cell Biol 2017 06 27;87:27-33. Epub 2017 Mar 27.

Free Radical Biochemistry Laboratory, School of Biological Sciences, University of Canterbury, Private Bag 4800, Christchurch, New Zealand; Department of Radiology, University of Otago, Christchurch, New Zealand. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2017.03.017DOI Listing
June 2017

Polymorphisms in CYP2C8 and CYP3A5 genes in the Nigerian population.

Drug Metab Pharmacokinet 2017 Jun 14;32(3):189-191. Epub 2016 Sep 14.

Department of Pathology & Carney Centre for Pharmacogenomics, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1016/j.dmpk.2016.09.001DOI Listing
June 2017

Allelic Dropout During Polymerase Chain Reaction due to G-Quadruplex Structures and DNA Methylation Is Widespread at Imprinted Human Loci.

G3 (Bethesda) 2017 03 10;7(3):1019-1025. Epub 2017 Mar 10.

Department of Pathology, University of Otago, Christchurch 8140, New Zealand

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http://dx.doi.org/10.1534/g3.116.038687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345703PMC
March 2017

Microsatellite polymorphisms associated with human behavioural and psychological phenotypes including a gene-environment interaction.

BMC Med Genet 2017 Feb 3;18(1):12. Epub 2017 Feb 3.

Department of Pathology, University of Otago, Christchurch, PO Box 4345, Christchurch, New Zealand.

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http://dx.doi.org/10.1186/s12881-017-0374-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291968PMC
February 2017

Mean telomere length is not associated with current health status in a 50-year-old population sample.

Am J Hum Biol 2017 Jan 26;29(1). Epub 2016 Aug 26.

Gene Structure and Function Laboratory, Department of Pathology, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1002/ajhb.22906DOI Listing
January 2017

[Letter to the Editor] Many commercial hot-start polymerases demonstrate activity prior to thermal activation.

Biotechniques 2016 12 1;61(6):293-296. Epub 2016 Dec 1.

Gene Structure and Function Laboratory, Department of Pathology, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.2144/000114481DOI Listing
December 2016

Genetic Evidence of a Population Bottleneck and Inbreeding in the Endangered New Zealand Sea Lion, Phocarctos hookeri.

J Hered 2016 09 19;107(5):392-402. Epub 2016 Mar 19.

From the Department of Anatomy, University of Otago, 270 Great King Street, Dunedin 9016, New Zealand (Osborne and Gemmell); Department of Pathology, University of Otago, Christchurch, New Zealand (Osborne and Kennedy); Computational Biology Group, Swiss Institute of Bioinformatics, Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland (Negro); Marine Species and Threats Team, Department of Conservation, Wellington, New Zealand (Chilvers); Department of Zoology, University of Otago, Dunedin, New Zealand (Robertson); and Allan Wilson Centre for Molecular Ecology and Evolution, University of Otago, Dunedin, New Zealand (Gemmell). B. Louise Chilvers is now at Wildbase, Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North 4442, New Zealand.

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http://dx.doi.org/10.1093/jhered/esw015DOI Listing
September 2016

DNA G-quadruplexes show strong interaction with DNA methyltransferases in vitro.

FEBS Lett 2016 09 11;590(17):2870-83. Epub 2016 Aug 11.

Department of Pathology, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1002/1873-3468.12331DOI Listing
September 2016

Fluorescence Methods for Probing G-Quadruplex Structure in Single- and Double-Stranded DNA.

Biochemistry 2016 07 16;55(26):3714-25. Epub 2016 Jun 16.

Department of Pathology, University of Otago , Christchurch, New Zealand.

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http://dx.doi.org/10.1021/acs.biochem.6b00327DOI Listing
July 2016

Personalised prescribing in psychiatry: Has pharmacogenomics delivered on its promise?

Aust N Z J Psychiatry 2016 Jun 24;50(6):509-10. Epub 2016 Mar 24.

Department of Pathology, University of Otago - Christchurch, Christchurch, New Zealand.

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http://dx.doi.org/10.1177/0004867416640099DOI Listing
June 2016

Examining the role of components of Slc11a1 (Nramp1) in the susceptibility of New Zealand sea lions (Phocarctos hookeri) to disease.

PLoS One 2015 14;10(4):e0122703. Epub 2015 Apr 14.

Department of Anatomy, University of Otago, Dunedin, New Zealand; Allan Wilson Centre for Molecular Ecology and Evolution, University of Otago, Dunedin, New Zealand.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122703PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397024PMC
April 2016

Impact of New Genomic Technologies on Understanding Adverse Drug Reactions.

Clin Pharmacokinet 2016 Apr;55(4):419-36

Department of Pathology and Carney Centre for Pharmacogenomics, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1007/s40262-015-0324-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791456PMC
April 2016

Erratum to: Impact of New Genomic Technologies on Understanding Adverse Drug Reactions.

Clin Pharmacokinet 2016 Apr;55(4):437

Department of Pathology and Carney Centre for Pharmacogenomics, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1007/s40262-016-0376-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969865PMC
April 2016

Cross-Comparison of Exome Analysis, Next-Generation Sequencing of Amplicons, and the iPLEX(®) ADME PGx Panel for Pharmacogenomic Profiling.

Front Pharmacol 2016 26;7. Epub 2016 Jan 26.

Carney Centre for Pharmacogenomics, Department of Pathology, University of Otago Christchurch, New Zealand.

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http://dx.doi.org/10.3389/fphar.2016.00001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726781PMC
February 2016

Valproic acid exposure leads to upregulation and increased promoter histone acetylation of sepiapterin reductase in a serotonergic cell line.

Neuropharmacology 2015 Dec 4;99:79-88. Epub 2015 Jul 4.

Gene Structure and Function Laboratory and Carney Centre for Pharmacogenomics, Department of Pathology, University of Otago, Christchurch, New Zealand. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2015.06.018DOI Listing
December 2015

No association between mean telomere length and life stress observed in a 30 year birth cohort.

PLoS One 2014 9;9(5):e97102. Epub 2014 May 9.

Gene Structure and Function Laboratory, Department of Pathology, University of Otago, Christchurch, New Zealand.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0097102PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016252PMC
June 2015

OPRM1 genotype and naltrexone response in depressed alcohol-dependent patients.

Pharmacogenet Genomics 2015 May;25(5):270-3

Departments of aPsychological Medicine bPathology, University of Otago Christchurch, Christchurch, New Zealand.

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http://dx.doi.org/10.1097/FPC.0000000000000128DOI Listing
May 2015

Choice of PCR microtube can impact on the success of long-range PCRs.

Anal Biochem 2015 May 9;477:115-7. Epub 2015 Mar 9.

Carney Centre for Pharmacogenomics and Department of Pathology, University of Otago, Christchurch, Christchurch, New Zealand. Electronic address:

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http://dx.doi.org/10.1016/j.ab.2015.02.023DOI Listing
May 2015

Heterozygote advantage at MHC DRB may influence response to infectious disease epizootics.

Mol Ecol 2015 Apr 19;24(7):1419-32. Epub 2015 Mar 19.

Department of Anatomy, University of Otago, PO Box 913, Dunedin, 9054, New Zealand; Department of Pathology, University of Otago, Christchurch, 8140, New Zealand.

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http://dx.doi.org/10.1111/mec.13128DOI Listing
April 2015

Telomere length measurement on the Roche LightCycler 480 Platform.

Genet Test Mol Biomarkers 2015 Feb 23;19(2):63-8. Epub 2014 Dec 23.

1 Gene Structure and Function Laboratory, Department of Pathology, University of Otago , Christchurch, Christchurch, New Zealand .

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http://www.liebertpub.com/doi/10.1089/gtmb.2014.0208
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http://dx.doi.org/10.1089/gtmb.2014.0208DOI Listing
February 2015

DUF1220 copy number is linearly associated with increased cognitive function as measured by total IQ and mathematical aptitude scores.

Hum Genet 2015 Jan 7;134(1):67-75. Epub 2014 Oct 7.

Department of Biochemistry and Molecular Genetics and Human Medical Genetics, Medical Scientist Training and Neuroscience Programs, University of Colorado School of Medicine, Anschutz Medical Campus, RC1-S, L18-10125, 12801 East 17th Ave, Mailstop 8101, P.O. Box 6511, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1007/s00439-014-1489-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898241PMC
January 2015

Stratification by smoking status reveals an association of CHRNA5-A3-B4 genotype with body mass index in never smokers.

PLoS Genet 2014 Dec 4;10(12):e1004799. Epub 2014 Dec 4.

BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, University of Glasgow, Glasgow, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1004799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4256159PMC
December 2014

Relevance of G-quadruplex structures to pharmacogenetics.

Front Pharmacol 2014 8;5:160. Epub 2014 Jul 8.

Department of Pathology, Carney Centre for Pharmacogenomics, University of Otago Christchurch, New Zealand.

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http://dx.doi.org/10.3389/fphar.2014.00160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085647PMC
July 2014

Novel CYP2D6 and CYP2C19 variants identified in a patient with adverse reactions towards venlafaxine monotherapy and dual therapy with nortriptyline and fluoxetine.

Pharmacogenet Genomics 2013 Sep;23(9):494-7

Department of Pathology and Carney Centre for Pharmacogenomics, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1097/FPC.0b013e328363688dDOI Listing
September 2013

Progressing the utilisation of pharmacogenetics and pharmacogenomics into clinical care.

Pathology 2013 06;45(4):357-70

Department of Molecular and Clinical Genetics, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1097/PAT.0b013e328360b66eDOI Listing
June 2013

Institutional profile: The Carney Centre for Pharmacogenomics: a New Zealand focus for personalized medicine research.

Pharmacogenomics 2012 Jun;13(8):865-8

Carney Centre for Pharmacogenomics & Department of Pathology, University of Otago, Christchurch, PO Box 4345, Christchurch, New Zealand.

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http://dx.doi.org/10.2217/pgs.12.55DOI Listing
June 2012

Moderating role of the MAOA genotype in antisocial behaviour.

Br J Psychiatry 2012 Feb;200(2):116-23

Christchurch Health and Development Study, University of Otago, Christchurch, PO Box 4345, Christchurch, New Zealand.

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http://dx.doi.org/10.1192/bjp.bp.111.093328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269651PMC
February 2012

MAOA, abuse exposure and antisocial behaviour: 30-year longitudinal study.

Br J Psychiatry 2011 Jun;198(6):457-63

Christchurch Health and Development Study, Department of Psychological Medicine, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1192/bjp.bp.110.086991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105117PMC
June 2011

Development of a predicted physical map of microsatellite locus positions for pinnipeds, with wider applicability to the Carnivora.

Mol Ecol Resour 2011 May 28;11(3):503-13. Epub 2010 Dec 28.

Department of Anatomy and Structural Biology, Centre for Reproduction and Genomics, University of Otago, Dunedin, New Zealand.

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http://dx.doi.org/10.1111/j.1755-0998.2010.02962.xDOI Listing
May 2011

Life stress, 5-HTTLPR and mental disorder: findings from a 30-year longitudinal study.

Br J Psychiatry 2011 Feb;198(2):129-35

Christchurch Health and Development Study, University of Otago, Christchurch, PO Box 4345, Christchurch, New Zealand.

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http://dx.doi.org/10.1192/bjp.bp.110.085993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031653PMC
February 2011

Clinical implications of pharmacogenetic variation on the effects of statins.

Drug Saf 2011 Jan;34(1):1-19

Department of Pharmacology and Toxicology, School of Medical Sciences, University of Otago, Dunedin, New Zealand.

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http://dx.doi.org/10.2165/11584380-000000000-00000DOI Listing
January 2011

Relationships between angry-impulsive personality traits and genetic polymorphisms of the dopamine transporter.

Biol Psychiatry 2009 Oct 15;66(8):717-21. Epub 2009 Apr 15.

Department of Psychological Medicine, University of Otago, Christchurch, Christchurch, New Zealand.

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http://dx.doi.org/10.1016/j.biopsych.2009.03.005DOI Listing
October 2009

Expression and association analyses of promoter variants of the neurogenic gene HES6, a candidate gene for mood disorder susceptibility and antidepressant response.

Neurosci Lett 2009 Aug 28;460(2):185-90. Epub 2009 May 28.

Gene Structure & Function Laboratory, Department of Pathology, University of Otago, Christchurch P.O. Box 4345, Christchurch, New Zealand.

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http://dx.doi.org/10.1016/j.neulet.2009.05.065DOI Listing
August 2009

Downregulation of Ccnd1 and Hes6 in rat hippocampus after chronic exposure to the antidepressant paroxetine.

Acta Neuropsychiatr 2008 Dec;20(6):307-13

1Department of Pathology, University of Otago, Christchurch, Christchurch, New Zealand.

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http://dx.doi.org/10.1111/j.1601-5215.2008.00334.xDOI Listing
December 2008

Incidence of Mycobacterium avium subspecies paratuberculosis in a population-based cohort of patients with Crohn's disease and control subjects.

Am J Gastroenterol 2008 May 26;103(5):1168-72. Epub 2008 Mar 26.

Department of Pathology, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1111/j.1572-0241.2007.01742.xDOI Listing
May 2008

Beyond TPMT: genetic influences on thiopurine drug responses in inflammatory bowel disease.

Per Med 2008 May;5(3):233-248

Department of Medicine, University of Otago, Christchurch 8140, New Zealand.

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http://dx.doi.org/10.2217/17410541.5.3.233DOI Listing
May 2008

Allele frequency differences of cytochrome P450 polymorphisms in a sample of New Zealand Māori.

N Z Med J 2008 Apr 18;121(1272):33-7. Epub 2008 Apr 18.

School of Biological Sciences, Victoria University of Wellington, New Zealand.

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April 2008

Proteomic analysis of embryonic stem cell-derived neural cells exposed to the antidepressant paroxetine.

J Neurosci Res 2008 Feb;86(2):306-16

Department of Pathology, University of Otago, Christchurch, New Zealand.

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http://dx.doi.org/10.1002/jnr.21482DOI Listing
February 2008

Role of epigenetics in mental disorders.

Aust N Z J Psychiatry 2008 Feb;42(2):97-107

Department of Pathology, University of Otago, Christchurch, New Zealand.

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http://journals.sagepub.com/doi/10.1080/00048670701787495
Publisher Site
http://dx.doi.org/10.1080/00048670701787495DOI Listing
February 2008

Ile164 variant of beta2-adrenoceptor does not influence outcome in heart failure but may interact with beta blocker treatment.

Eur J Heart Fail 2008 Jan;10(1):55-9

Department of Pathology and Carney Centre for Pharmacogenomics, University of Otago, Christchurch, PO Box 4345, Christchurch, New Zealand.

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http://dx.doi.org/10.1016/j.ejheart.2007.10.011DOI Listing
January 2008

IL23R R381Q and ATG16L1 T300A are strongly associated with Crohn's disease in a study of New Zealand Caucasians with inflammatory bowel disease.

Am J Gastroenterol 2007 Dec 25;102(12):2754-61. Epub 2007 Sep 25.

Department of Pathology, University of Otago, Christchurch School of Medicine & Health Sciences, Christchurch, New Zealand.

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http://dx.doi.org/10.1111/j.1572-0241.2007.01525.xDOI Listing
December 2007

Benzylpiperazine: a drug of abuse?

J Psychopharmacol 2007 Nov 2;21(8):888-94. Epub 2007 Jul 2.

Envirogenomics Group, Institute of Environmental Science and Research Ltd, Porirua, New Zealand.

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http://dx.doi.org/10.1177/0269881107077260DOI Listing
November 2007

Effect of inflammatory bowel disease classification changes on NOD2 genotype-phenotype associations in a population-based cohort.

Inflamm Bowel Dis 2007 Oct;13(10):1220-7

Department of Gastroenterology, Christchurch School of Medicine and Christchurch Hospital, Christchurch 8140, New Zealand.

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http://dx.doi.org/10.1002/ibd.20190DOI Listing
October 2007

Bipolar disorder not otherwise specified: comparison with bipolar disorder I/II and major depression.

Aust N Z J Psychiatry 2007 Oct;41(10):843-9

University of Otago Christchurch, Christchurch, New Zealand.

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http://dx.doi.org/10.1080/00048670701579058DOI Listing
October 2007

Pharmacogenomics: single genes, whole genomes and global networks.

Authors:
Martin A Kennedy

Per Med 2007 Feb;4(1):87-94

Carney Centre for Pharmacogenomics, University of Otago (Christchurch), PO Box 4345, Christchurch, New Zealand.

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http://dx.doi.org/10.2217/17410541.4.1.87DOI Listing
February 2007

An association study of DRD2 and COMT polymorphisms with novelty seeking and harm avoidance scores, in two independent samples of depressed patients.

Behav Brain Funct 2007 Jan 11;3. Epub 2007 Jan 11.

Department of Psychological Medicine, Christchurch School of Medicine & Health Sciences, PO Box 4345, Christchurch, New Zealand.

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http://dx.doi.org/10.1186/1744-9081-3-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1779796PMC
January 2007

Preliminary evidence for an association between a dopamine D3 receptor gene variant and obsessive-compulsive personality disorder in patients with major depression.

Am J Med Genet B Neuropsychiatr Genet 2006 Jun;141B(4):409-13

Department of Psychological Medicine, Christchurch School of Medicine & Health Sciences, Christchurch, New Zealand.

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http://dx.doi.org/10.1002/ajmg.b.30308DOI Listing
June 2006

A dopamine transporter polymorphism is a risk factor for borderline personality disorder in depressed patients.

Psychol Med 2006 Jun 20;36(6):807-13. Epub 2006 Apr 20.

Department of Psychological Medicine, Christchurch School of Medicine & Health Sciences, Christchurch, New Zealand.

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http://dx.doi.org/10.1017/S0033291706007288DOI Listing
June 2006

Linking pharmacovigilance with pharmacogenetics.

Drug Saf 2004 ;27(15):1171-84

The New Zealand Intensive Medicines Monitoring Programme (IMMP), New Zealand Pharmacovigilance Centre, Department of Preventive and Social Medicine, Dunedin School of Medicine, Dunedin, New Zealand.

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http://dx.doi.org/10.2165/00002018-200427150-00002DOI Listing
April 2006

Rapid detection of common cytochrome P450 2D6 alleles in Caucasians.

Clin Chim Acta 2006 Apr 20;366(1-2):348-51. Epub 2005 Dec 20.

Department of Pathology, Christchurch School of Medicine and Health Sciences, PO Box 4345, Christchurch, New Zealand.

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http://dx.doi.org/10.1016/j.cca.2005.11.008DOI Listing
April 2006

Genetic, developmental and personality correlates of self-mutilation in depressed patients.

Aust N Z J Psychiatry 2006 Mar;40(3):225-9

Department of Psychological Medicine, Christchurch School of Medicine and Health Sciences, New Zealand.

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http://dx.doi.org/10.1080/j.1440-1614.2006.01778.xDOI Listing
March 2006

Bronchodilator response in relation to beta2-adrenoceptor haplotype in patients with asthma.

Am J Respir Crit Care Med 2005 Sep 23;172(6):700-3. Epub 2005 Jun 23.

Otago Respiratory Research Unit and Department of Preventive and Social Medicine, Dunedin School of Medicine, New Zealand.

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http://dx.doi.org/10.1164/rccm.200501-092OCDOI Listing
September 2005

Reversed diurnal variation in depression: associations with a differential antidepressant response, tryptophan: large neutral amino acid ratio and serotonin transporter polymorphisms.

Psychol Med 2005 Apr;35(4):511-7

Department of Psychological Medicine, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand.

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April 2005

Rapid detection of common CARD15 variants in patients with inflammatory bowel disease.

Mol Diagn 2004 ;8(2):101-5

Department of Pathology, Christchurch School of Medicine and Health Sciences, University of Otago, New Zealand.

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December 2004

Lack of association between the ITPA 94C>A polymorphism and adverse effects from azathioprine.

Pharmacogenetics 2004 Nov;14(11):779-81

Department of Medicine, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand.

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November 2004

Association between cytochrome P450 2D6 genotype and harm avoidance.

Am J Med Genet B Neuropsychiatr Genet 2004 May;127B(1):90-3

Department of Pathology, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand.

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http://dx.doi.org/10.1002/ajmg.b.20163DOI Listing
May 2004

A multiplexed allele-specific polymerase chain reaction assay for the detection of common thiopurine S-methyltransferase (TPMT) mutations.

Clin Chim Acta 2004 Mar;341(1-2):49-53

Department of Pathology, Christchurch School of Medicine and Health Sciences, University of Otago, PO Box 4345, Christchurch, New Zealand.

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http://linkinghub.elsevier.com/retrieve/pii/S000989810300533
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http://dx.doi.org/10.1016/j.cccn.2003.10.029DOI Listing
March 2004

No evidence of increased adverse drug reactions in cytochrome P450 CYP2D6 poor metabolizers treated with fluoxetine or nortriptyline.

Hum Psychopharmacol 2004 Jan;19(1):17-23

Department of Pathology, Christchurch School of Medicine & Health Sciences, University of Otago, PO Box 4345, Christchurch, New Zealand.

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http://dx.doi.org/10.1002/hup.539DOI Listing
January 2004

Age-dependent antidepressant pharmacogenomics: polymorphisms of the serotonin transporter and G protein beta3 subunit as predictors of response to fluoxetine and nortriptyline.

Int J Neuropsychopharmacol 2003 Dec;6(4):339-46

Department of Psychological Medicine, Christchurch School of Medicine and Health Sciences, P.O. Box 4345, Christchurch, New Zealand.

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http://dx.doi.org/10.1017/S1461145703003663DOI Listing
December 2003

Correlation of CYP2D6 genotype with perhexiline phenotypic metabolizer status.

Pharmacogenetics 2003 Oct;13(10):627-32

Department of Clinical Pharmacology, Christchurch Hospital and Department of Pathology, Christchurch, New Zealand.

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http://dx.doi.org/10.1097/01.fpc.0000054129.14659.efDOI Listing
October 2003

Polymorphisms of DRD4 and DRD3 and risk of avoidant and obsessive personality traits and disorders.

Psychiatry Res 2003 Jul;119(1-2):1-10

Department of Psychological Medicine, Christchurch School of Medicine and Health Sciences, P.O. Box 4345, Christchurch, New Zealand.

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July 2003

Determination of beta2-adrenergic receptor (ADRB2) haplotypes by a multiplexed polymerase chain reaction assay.

Hum Mutat 2002 Dec;20(6):479

Gene Structure and Function Laboratory, Department of Pathology, Christchurch School of Medicine and Health Sciences, University of Otago, P.O. Box 4345, Christchurch, New Zealand.

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http://dx.doi.org/10.1002/humu.9091DOI Listing
December 2002

Cytochrome P450 2D6 genotype does not predict SSRI (fluoxetine or paroxetine) induced hyponatraemia.

Hum Psychopharmacol 2002 Jun;17(4):187-90

Department of Clinical Pharmacology, Christchurch Hospital, Christchurch School of Medicine, Christchurch, New Zealand.

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http://dx.doi.org/10.1002/hup.394DOI Listing
June 2002

Gene transfer between Salmonella enterica serovar Typhimurium inside epithelial cells.

J Bacteriol 2002 Apr;184(8):2235-42

Department of Plant and Microbial Sciences, University of Canterbury, Christchurch, New Zealand.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC134967PMC
http://dx.doi.org/10.1128/jb.184.8.2235-2242.2002DOI Listing
April 2002

A polymorphism in the dopamine beta-hydroxylase gene is associated with "paranoid ideation" in patients with major depression.

Biol Psychiatry 2002 Mar;51(5):365-9

Department of Pathology, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand.

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http://dx.doi.org/10.1016/s0006-3223(01)01367-1DOI Listing
March 2002

Beta-adrenergic receptor polymorphisms and drug responses in asthma.

Pharmacogenomics 2002 Mar;3(2):173-84

Department of Medicine, Dunedin School of Medicine, University of Otago, PO Box 913, Dunedin, New Zealand.

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http://dx.doi.org/10.1517/14622416.3.2.173DOI Listing
March 2002

How the pharmacogenetics of cytochrome P450 enzymes may affect prescribing.

N Z Med J 2002 Mar;115(1150):137-40

Department of Pathology, Christchurch School of Medicine and Health Sciences.

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March 2002