Martijn C Nawijn

Martijn C Nawijn

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Martijn C Nawijn

Martijn C Nawijn

Publications by authors named "Martijn C Nawijn"

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48Publications

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Applying the CAMP trial asthma remission prediction model to the Dutch asthma remission studies.

J Allergy Clin Immunol 2019 May 12;143(5):1973-1975. Epub 2019 Mar 12.

Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Department of Pulmonology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2019.01.040DOI Listing
May 2019

A review on the pathophysiology of asthma remission.

Pharmacol Ther 2019 May 8. Epub 2019 May 8.

University of Groningen, University Medical Center Groningen, Groningen, Research Institute for Asthma and COPD (GRIAC), Groningen, the Netherlands; University of Groningen, University Medical Center Groningen, Department of Pulmonology, Groningen, the Netherlands.

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http://dx.doi.org/10.1016/j.pharmthera.2019.05.002DOI Listing
May 2019

Subcutaneous immunotherapy using modified Phl p5a-derived peptides efficiently alleviates allergic asthma in mice.

Allergy 2019 May 23. Epub 2019 May 23.

Department of Pathology & Medical Biology, Experimental Pulmonary and Inflammatory Research (EXPIRE), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1111/all.13918DOI Listing
May 2019

The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution.

Dev Cell 2019 Apr 28;49(1):10-29. Epub 2019 Mar 28.

Department of Biomedical Informatics, University of Cincinnati College of Medicine, and Cincinnati Children's Hospital Medical Center, Division of Biomedical Informatics, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1016/j.devcel.2019.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616346PMC
April 2019

DNA methylation in childhood asthma: an epigenome-wide meta-analysis.

Lancet Respir Med 2018 05 26;6(5):379-388. Epub 2018 Feb 26.

GRIAC research institute Groningen, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands; Department of Pediatric Pulmonology and Pediatric Allergy, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(18)30052-3DOI Listing
May 2018

Genetic regulation of methylation and IL1RL1-a protein levels in asthma.

Eur Respir J 2018 03 8;51(3). Epub 2018 Mar 8.

Dept of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

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http://dx.doi.org/10.1183/13993003.01377-2017DOI Listing
March 2018

Subcutaneous and Sublingual Immunotherapy in a Mouse Model of Allergic Asthma.

Methods Mol Biol 2017 ;1559:137-168

Department of Pathology and Medical Biology, Laboratory of Experimental Pulmonology and Inflammation Research (EXPIRE), University Medical Center Groningen, University of Groningen, Hanzeplein 1 (EA52/T2.212), 9713 GZ, Groningen, The Netherlands.

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http://dx.doi.org/10.1007/978-1-4939-6786-5_11DOI Listing
January 2018

Genetic variance is associated with susceptibility for cigarette smoke-induced DAMP release in mice.

Am J Physiol Lung Cell Mol Physiol 2017 Sep 8;313(3):L559-L580. Epub 2017 Jun 8.

Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1152/ajplung.00466.2016DOI Listing
September 2017

Increased neutrophil expression of pattern recognition receptors during COPD exacerbations.

Respirology 2017 02 27;22(2):401-404. Epub 2016 Sep 27.

Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1111/resp.12912DOI Listing
February 2017

Mechanisms of the Development of Allergy (MeDALL): Introducing novel concepts in allergy phenotypes.

J Allergy Clin Immunol 2017 02;139(2):388-399

Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, GRIAC Research Institute, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jaci.2016.12.940DOI Listing
February 2017

Susceptibility for cigarette smoke-induced DAMP release and DAMP-induced inflammation in COPD.

Am J Physiol Lung Cell Mol Physiol 2016 11 9;311(5):L881-L892. Epub 2016 Sep 9.

Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1152/ajplung.00135.2016DOI Listing
November 2016

Inhibition of Pim1 kinase, new therapeutic approach in virus-induced asthma exacerbations.

Eur Respir J 2016 Mar 11;47(3):783-91. Epub 2016 Feb 11.

Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UK National Institute for Health Research, Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, UK.

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http://dx.doi.org/10.1183/13993003.00171-2015DOI Listing
March 2016

Cigarette smoke-induced necroptosis and DAMP release trigger neutrophilic airway inflammation in mice.

Am J Physiol Lung Cell Mol Physiol 2016 Feb 30;310(4):L377-86. Epub 2015 Dec 30.

Department of Pathology and Medical Biology, Experimental Pulmonology and Inflammation Research, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; GRIAC Research Institute, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands;

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http://dx.doi.org/10.1152/ajplung.00174.2015DOI Listing
February 2016

Mouse protocadherin-1 gene expression is regulated by cigarette smoke exposure in vivo.

PLoS One 2014 3;9(7):e98197. Epub 2014 Jul 3.

Laboratory of Allergology and Pulmonary Diseases, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen (UMCG), Groningen, the Netherlands; GRIAC research institute, University of Groningen, University Medical Center Groningen (UMCG), Groningen, the Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0098197PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081120PMC
November 2015

Protocadherin-1 binds to SMAD3 and suppresses TGF-β1-induced gene transcription.

Am J Physiol Lung Cell Mol Physiol 2015 Oct 24;309(7):L725-35. Epub 2015 Jul 24.

University of Groningen, University Medical Center Groningen, Experimental Pulmonology and Inflammation Research (EXPIRE), Department of Pathology & Medical Biology, Groningen, The Netherlands; GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands;

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http://dx.doi.org/10.1152/ajplung.00346.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593836PMC
October 2015

Inhibition of Pim1 kinase reduces viral replication in primary bronchial epithelial cells.

Eur Respir J 2015 Jun 5;45(6):1745-8. Epub 2015 Mar 5.

Brooke Laboratory, Academic Unit of Clinical and Experimental Sciences, University of Southampton, Faculty of Medicine, University Hospital Southampton, Southampton, UK National Institute for Health Research Respiratory Biomedical Research Unit, University Hospital Southampton, Southampton, UK.

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http://dx.doi.org/10.1183/09031936.00206514DOI Listing
June 2015

Increased serum levels of LL37, HMGB1 and S100A9 during exacerbation in COPD patients.

Eur Respir J 2015 May;45(5):1482-5

Dept of Pathology and Medical Biology, Experimental Pulmonology and Inflammation Research, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands Dept of Pulmonology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1183/09031936.00158414DOI Listing
May 2015

Genetic variation associates with susceptibility for cigarette smoke-induced neutrophilia in mice.

Am J Physiol Lung Cell Mol Physiol 2015 Apr 30;308(7):L693-709. Epub 2015 Jan 30.

University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, Experimental Pulmonology and Inflammation Research, Groningen, The Netherlands; GRIAC Research Institute, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands;

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http://dx.doi.org/10.1152/ajplung.00118.2014DOI Listing
April 2015

The role of the IL-33/IL-1RL1 axis in mast cell and basophil activation in allergic disorders.

Mol Immunol 2015 Jan 10;63(1):80-5. Epub 2014 Jul 10.

University of Groningen, Laboratory of Allergology and Pulmonary Diseases, Department of Pathology and Medical Biology, University Medical Center Groningen, Groningen, The Netherlands; GRIAC research institute, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.molimm.2014.06.018DOI Listing
January 2015

Basophil activation test in mastocytosis patients with and without wasp venom allergy.

Cytometry B Clin Cytom 2015 Jan 28;88(1). Epub 2014 Aug 28.

Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran; Department of Pathology and Medical Biology, Laboratory of Allergology and Pulmonary Diseases, University Medical Center of Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1002/cyto.b.21181DOI Listing
January 2015

Protease-activated receptor-2 activation contributes to house dust mite-induced IgE responses in mice.

PLoS One 2014 20;9(3):e91206. Epub 2014 Mar 20.

Lab. Allergology & Pulmonary Diseases, Department of Pathology & Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; GRIAC Research Institute, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0091206PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961228PMC
December 2014

Basophil activation test in the diagnosis and monitoring of mastocytosis patients with wasp venom allergy on immunotherapy.

Cytometry B Clin Cytom 2014 May 29;86(3):183-90. Epub 2014 Jan 29.

Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran; Department of Pathology and Medical Biology, Laboratory of Allergology and Pulmonary Diseases, University Medical Center of Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1002/cyto.b.21148DOI Listing
May 2014

A specific DAMP profile identifies susceptibility to smoke-induced airway inflammation.

Eur Respir J 2014 Apr 5;43(4):1183-6. Epub 2013 Dec 5.

Laboratory of Allergology and Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen.

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http://dx.doi.org/10.1183/09031936.00127813DOI Listing
April 2014

Protocadherin-1: Epithelial barrier dysfunction in asthma and eczema.

Eur Respir J 2014 Mar;43(3):671-4

University Medical Center Groningen, Beatrix Children's Hospital, Dept of Pediatric Pulmonology and Pediatric Allergology, Groningen.

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http://dx.doi.org/10.1183/09031936.00179713DOI Listing
March 2014

TLR-2 activation induces regulatory T cells and long-term suppression of asthma manifestations in mice.

PLoS One 2013 5;8(2):e55307. Epub 2013 Feb 5.

Laboratory of Allergology and Pulmonary Diseases, Department of Pathology and Medical Biology, University of Groningen, GRIAC Research Institute, University Medical Centre Groningen-UMCG, Groningen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0055307PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564817PMC
August 2013

Decoding asthma: translating genetic variation in IL33 and IL1RL1 into disease pathophysiology.

J Allergy Clin Immunol 2013 Mar 4;131(3):856-65. Epub 2013 Feb 4.

Laboratory of Allergology and Pulmonary Diseases, Department of Pathology and Medical Biology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jaci.2012.11.028DOI Listing
March 2013

Understanding the complexity of IgE-related phenotypes from childhood to young adulthood: a Mechanisms of the Development of Allergy (MeDALL) seminar.

J Allergy Clin Immunol 2012 Apr 3;129(4):943-54.e4. Epub 2012 Mar 3.

Centre for Research in Environmental Epidemiology, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.jaci.2012.01.047DOI Listing
April 2012

Recent advances in the epigenetics and genomics of asthma.

Curr Opin Allergy Clin Immunol 2011 Oct;11(5):414-9

Department of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1097/ACI.0b013e32834a9573DOI Listing
October 2011

Identification of the Mhc region as an asthma susceptibility locus in recombinant congenic mice.

Am J Respir Cell Mol Biol 2011 Aug 22;45(2):295-303. Epub 2010 Oct 22.

Laboratory of Allergology & Pulmonary Diseases, Department of Pathology and Medical Biology, GRIAC Research Institute, University Medical Centre Groningen, University of Groningen, the Netherlands.

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http://dx.doi.org/10.1165/rcmb.2009-0369OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266060PMC
August 2011

E-cadherin: gatekeeper of airway mucosa and allergic sensitization.

Trends Immunol 2011 Jun 12;32(6):248-55. Epub 2011 Apr 12.

Department of Pathology & Medical Biology, GRIAC Research Institute, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.it.2011.03.004DOI Listing
June 2011

Pim3 negatively regulates glucose-stimulated insulin secretion.

Islets 2010 Sep-Oct;2(5):308-17. Epub 2010 Sep 1.

Department of Medicine, University of Chicago, Chicago, IL, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025049PMC
http://dx.doi.org/10.4161/isl.2.5.13058DOI Listing
May 2011

For better or for worse: the role of Pim oncogenes in tumorigenesis.

Nat Rev Cancer 2011 Jan 9;11(1):23-34. Epub 2010 Dec 9.

Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, The Netherlands.

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http://www.nature.com/articles/nrc2986
Publisher Site
http://dx.doi.org/10.1038/nrc2986DOI Listing
January 2011

Suppression of Th2-driven airway inflammation by allergen immunotherapy is independent of B cell and Ig responses in mice.

J Immunol 2010 Oct 27;185(7):3857-65. Epub 2010 Aug 27.

Laboratory of Allergology and Pulmonary Diseases, Department of Pathology and Medical Biology, Groningen Research Institute for Asthma and COPD Research, University Medical Center Groningen, University of Groningen, Groningen;

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http://www.jimmunol.org/content/185/7/3857.full.pdf
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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.0903909
Publisher Site
http://dx.doi.org/10.4049/jimmunol.0903909DOI Listing
October 2010

GITR signaling potentiates airway hyperresponsiveness by enhancing Th2 cell activity in a mouse model of asthma.

Respir Res 2009 Oct 7;10:93. Epub 2009 Oct 7.

Laboratory of Allergology and Pulmonary diseases, Department of Pathology and Medical Biology, University Medical Centre Groningen (UMCG), Groningen University, Groningen, The Netherlands.

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http://dx.doi.org/10.1186/1465-9921-10-93DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2767348PMC
October 2009

Cutting edge: Suppressor of cytokine signaling 3 inhibits activation of NFATp.

J Immunol 2002 May;168(9):4277-81

Integrated Program in Molecular, Cellular, and Biophysical Studies, Columbia College of Physicians and Surgeons, New York, NY 10032, USA.

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http://dx.doi.org/10.4049/jimmunol.168.9.4277DOI Listing
May 2002

Pim serine/threonine kinases regulate the stability of Socs-1 protein.

Proc Natl Acad Sci U S A 2002 Feb;99(4):2175-80

Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1073/pnas.042035699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC122338PMC
February 2002