Publications by authors named "Martijn C G J Brouwers"

56Publications

Development and validation of a UPLC-MS/MS method to quantify fructose in serum and urine.

J Chromatogr B Analyt Technol Biomed Life Sci 2020 Oct 1;1155:122299. Epub 2020 Aug 1.

Laboratory for Metabolism and Vascular Medicine, Division of General Internal Medicine, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, the Netherlands; CARIM School for Cardiovascular Diseases, Maastricht, the Netherlands.

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October 2020

Kidney and vascular function in adult patients with hereditary fructose intolerance.

Mol Genet Metab Rep 2020 Jun 11;23:100600. Epub 2020 May 11.

Division of Endocrinology, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.

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June 2020

Incidence of type 2 diabetes in familial combined hyperlipidemia.

BMJ Open Diabetes Res Care 2020 03;8(1)

Department of Internal Medicine, Division of General Internal Medicine, Laboratory for Metabolism and Vascular Medicine, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands.

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March 2020

Recent advances in the pathogenesis of hereditary fructose intolerance: implications for its treatment and the understanding of fructose-induced non-alcoholic fatty liver disease.

Cell Mol Life Sci 2020 May 12;77(9):1709-1719. Epub 2019 Nov 12.

Division of Endocrinology, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.

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May 2020

Non-alcoholic fatty liver disease and cardiovascular disease: assessing the evidence for causality.

Diabetologia 2020 02 11;63(2):253-260. Epub 2019 Nov 11.

Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, the Netherlands.

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February 2020

Relevant patient characteristics for estimating healthcare needs according to healthcare providers and people with type 2 diabetes: a Delphi survey.

BMC Health Serv Res 2019 Aug 16;19(1):575. Epub 2019 Aug 16.

Department of Health Services Research, CAPHRI Care and Public Health Research Institute, Faculty of Health, Medicine and Life Sciences, Maastricht University, Duboisdomein 30, 6229, GT, Maastricht, the Netherlands.

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August 2019

Relationship Between Nonalcoholic Fatty Liver Disease Susceptibility Genes and Coronary Artery Disease.

Hepatol Commun 2019 Apr 11;3(4):587-596. Epub 2019 Feb 11.

Cardiovascular Research Institute Maastricht, Maastricht University Maastricht the Netherlands.

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April 2019

Incidence of cardiovascular disease in familial combined hyperlipidemia: A 15-year follow-up study.

Atherosclerosis 2019 01 8;280:1-6. Epub 2018 Nov 8.

Department of Internal Medicine, Division of Endocrinology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre, P. Debyelaan 25, 6229 HX, Maastricht, the Netherlands. Electronic address:

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January 2019

Association of common gene variants in glucokinase regulatory protein with cardiorenal disease: A systematic review and meta-analysis.

PLoS One 2018 23;13(10):e0206174. Epub 2018 Oct 23.

Department of Internal Medicine, Division of Endocrinology, Maastricht University Medical Center, Maastricht, The Netherlands.

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April 2019

Non-alcoholic fatty liver disease concerns with glucokinase activators.

Lancet Diabetes Endocrinol 2018 09;6(9):684-685

Department of Internal Medicine, Division of Endocrinology and Metabolic Diseases, Maastricht University Medical Centre, Maastricht, 6200 MD, Netherlands. Electronic address:

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September 2018

Relevant patient characteristics for guiding tailored integrated diabetes primary care: a systematic review.

Prim Health Care Res Dev 2018 09 6;19(5):424-447. Epub 2018 Feb 6.

1Department of Health Services Research,CAPHRI Care and Public Health Research Institute, Faculty of Health, Medicine and Life Sciences,Maastricht University,Maastricht,The Netherlands.

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September 2018

A risk score including body mass index, glycated haemoglobin and triglycerides predicts future glycaemic control in people with type 2 diabetes.

Diabetes Obes Metab 2018 03 24;20(3):681-688. Epub 2017 Nov 24.

Department of Health Services Research, Care and Public Health Research Institute, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.

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March 2018

PNPLA3, TM6SF2, and MBOAT7 Genotypes and Coronary Artery Disease.

Gastroenterology 2017 03 1;152(4):912-913. Epub 2017 Feb 1.

Department of Internal Medicine, Division of Endocrinology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre, Maastricht, the Netherlands.

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March 2017

Prognostic value of plasma lactate levels in a retrospective cohort presenting at a university hospital emergency department.

BMJ Open 2017 01 30;7(1):e011450. Epub 2017 Jan 30.

Section of Acute Medicine, Division of General Medicine, Department of Internal Medicine, Maastricht University Medical Centre+, School of CAPHRI, Maastricht University, Maastricht, The Netherlands.

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January 2017

A Common Gene Variant in Glucokinase Regulatory Protein Interacts With Glucose Metabolism on Diabetic Dyslipidemia: the Combined CODAM and Hoorn Studies.

Diabetes Care 2016 Oct;39(10):1811-7

Division of Endocrinology, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, the Netherlands Laboratory for Metabolism and Vascular Medicine, Division of General Internal Medicine, Department of Internal Medicine, Maastricht University Medical Center, Maastricht, the Netherlands Cardiovascular Research Institute Maastricht (CARIM), Maastricht, the Netherlands

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October 2016

Risk of hypoglycaemia in users of sulphonylureas compared with metformin in relation to renal function and sulphonylurea metabolite group: population based cohort study.

BMJ 2016 Jul 13;354:i3625. Epub 2016 Jul 13.

Department of Clinical Pharmacy, Maastricht University Medical Centre, Maastricht, Netherlands Care and Public Health Research Institute (CAPHRI), Maastricht, Netherlands Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences Utrecht University, PO Box 80082, 3508 TB Utrecht, Netherlands.

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July 2016

Modulation of Glucokinase Regulatory Protein: A Double-Edged Sword?

Trends Mol Med 2015 Oct;21(10):583-594

Department of Internal Medicine, Division of Endocrinology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, P. Debyelaan 25, 6229 HX Maastricht, The Netherlands.

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October 2015

Elevated lactate levels in patients with poorly regulated type 1 diabetes and glycogenic hepatopathy: a new feature of Mauriac syndrome.

Diabetes Care 2015 Feb;38(2):e11-2

Charles Dent Metabolic Unit, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, U.K.

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February 2015

Familial combined hyperlipidemia: from molecular insights to tailored therapy.

Curr Opin Lipidol 2014 Jun;25(3):176-82

aDepartments of Internal Medicine and Endocrinology, Maastricht University Medical Centre bCARIM School for Cardiovascular Diseases/Laboratory for Metabolism and Vascular Medicine, Maastricht University, Maastricht cDivision of Vascular Medicine, Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.

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June 2014

Circulating PCSK9 is a strong determinant of plasma triacylglycerols and total cholesterol in homozygous carriers of apolipoprotein ε2.

Clin Sci (Lond) 2014 May;126(9):679-84

*Department of Internal Medicine, Divisions of General Internal Medicine and Endocrinology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maasctricht, The Netherlands.

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May 2014

The genetics of familial combined hyperlipidaemia.

Nat Rev Endocrinol 2012 Feb 14;8(6):352-62. Epub 2012 Feb 14.

Department of Internal Medicine and Endocrinology, Maastricht University Medical Centre, P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands.

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February 2012

Plasma proprotein convertase subtilisin kexin type 9 is a heritable trait of familial combined hyperlipidaemia.

Clin Sci (Lond) 2011 Nov;121(9):397-403

Department of Internal Medicine, Division of General Internal Medicine, Cardiovascular Research Institute Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands.

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November 2011

Novel drugs in familial combined hyperlipidemia: lessons from type 2 diabetes mellitus.

Curr Opin Lipidol 2010 Dec;21(6):530-8

Laboratory of Vascular Medicine and Metabolism, Department of Internal Medicine, Divisions of General Internal Medicine and Endocrinology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.

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December 2010

Increased arterial stiffness in familial combined hyperlipidemia.

J Hypertens 2009 May;27(5):1009-16

Department of Internal Medicine and Endocrinology, Maastricht University Medical Centre, Maastricht, The Netherlands.

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May 2009

Plasma pigment epithelium-derived factor is positively associated with obesity in Caucasian subjects, in particular with the visceral fat depot.

Eur J Endocrinol 2008 Dec 11;159(6):713-8. Epub 2008 Sep 11.

Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands.

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December 2008

Fatty liver--based identification of two distinct hypertriglyceridemic subgroups in familial combined hyperlipidemia.

Metabolism 2007 Oct;56(10):1311-7

Laboratory of Molecular Metabolism and Endocrinology, Department of Medicine, University Hospital Maastricht, PO Box 616, 6200 MD Maastricht, The Netherlands.

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October 2007

The circulating PBEF/NAMPT/visfatin level is associated with a beneficial blood lipid profile.

Pflugers Arch 2007 Sep 12;454(6):971-6. Epub 2007 Apr 12.

Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht, Maastricht University, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.

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September 2007

Heritability and genetic loci of fatty liver in familial combined hyperlipidemia.

J Lipid Res 2006 Dec 13;47(12):2799-807. Epub 2006 Sep 13.

Department of Medicine and Cardiovascular Research Institute Maastricht, Academic Hospital Maastricht, Maastricht, The Netherlands.

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December 2006

Radiological evidence of nonalcoholic fatty liver disease in familial combined hyperlipidemia.

Am J Med 2004 Jun;116(12):847-9

Cardiovascular Research Institute Maastricht, Laboratory of Molecular Metabolism and Endocrinology, Department of Medicine, University of Maastricht, Maastricht, The Netherlands.

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June 2004