Martha Constantine-Paton

Martha Constantine-Paton

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Martha Constantine-Paton

Martha Constantine-Paton

Publications by authors named "Martha Constantine-Paton"

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37Publications

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Synaptic Effects of Dopamine Breakdown and Their Relation to Schizophrenia-Linked Working Memory Deficits.

Front Synaptic Neurosci 2018 12;10:16. Epub 2018 Jun 12.

McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, United States.

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http://dx.doi.org/10.3389/fnsyn.2018.00016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008544PMC
June 2018

The Conserved VPS-50 Protein Functions in Dense-Core Vesicle Maturation and Acidification and Controls Animal Behavior.

Curr Biol 2016 Apr 3;26(7):862-71. Epub 2016 Mar 3.

Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA; McGovern Institute for Brain Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2016.01.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821696PMC
April 2016

A Diencephalic Dopamine Source Provides Input to the Superior Colliculus, where D1 and D2 Receptors Segregate to Distinct Functional Zones.

Cell Rep 2015 Nov 22;13(5):1003-15. Epub 2015 Oct 22.

McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.celrep.2015.09.046DOI Listing
November 2015

Editorial: Cell and molecular signaling, and transport pathways involved in growth factor control of synaptic development and function.

Front Synaptic Neurosci 2015 4;7. Epub 2015 Jun 4.

Division of Life Science, Hong Kong University of Science and Technology Hong Kong, China ; Molecular Neuroscience Center and Hong Kong University of Science and Technology Hong Kong, China ; State Key Laboratory of Molecular Neuroscience, Hong Kong University of Science and Technology Hong Kong, China.

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http://dx.doi.org/10.3389/fnsyn.2015.00008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454881PMC
June 2015

Postsynaptic localization of PSD-95 is regulated by all three pathways downstream of TrkB signaling.

Front Synaptic Neurosci 2014 31;6. Epub 2014 Mar 31.

McGovern Institute for Brain Research, Massachusetts Institute of Technology Cambridge, MA, USA ; Constantine-Paton Laboratory, Department of Brain and Cognitive Science, McGovern Institute for Brain Research, Massachusetts Institute of Technology Cambridge, MA USA ; Department of Biology, McGovern Institute for Brain Research, Massachusetts Institute of Technology Cambridge, MA, USA.

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http://dx.doi.org/10.3389/fnsyn.2014.00006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978359PMC
April 2014

Independent optical excitation of distinct neural populations.

Nat Methods 2014 Mar 9;11(3):338-46. Epub 2014 Feb 9.

1] The MIT Media Laboratory, Synthetic Neurobiology Group, Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA. [2] Department of Biological Engineering, MIT, Cambridge, Massachusetts, USA. [3] MIT Center for Neurobiological Engineering, MIT, Cambridge, Massachusetts, USA. [4] Department of Brain and Cognitive Sciences, MIT, Cambridge, Massachusetts, USA. [5] MIT McGovern Institute for Brain Research, MIT, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/nmeth.2836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943671PMC
March 2014

Homocysteine reduces NMDAR desensitization and differentially modulates peak amplitude of NMDAR currents, depending on GluN2 subunit composition.

J Neurophysiol 2013 Oct 17;110(7):1567-82. Epub 2013 Jul 17.

McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.

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http://dx.doi.org/10.1152/jn.00809.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042420PMC
October 2013

A Myosin Va mutant mouse with disruptions in glutamate synaptic development and mature plasticity in visual cortex.

J Neurosci 2013 May;33(19):8472-82

Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.4585-12.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699337PMC
May 2013

Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway.

J Neurosci 2013 Mar;33(11):5040-52

McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.2896-12.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632365PMC
March 2013

Eye opening and PSD95 are required for long-term potentiation in developing superior colliculus.

Proc Natl Acad Sci U S A 2013 Jan 24;110(2):707-12. Epub 2012 Dec 24.

McGovern Institute for Brain Research and Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://www.pnas.org/content/110/2/707.full.pdf
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http://www.pnas.org/cgi/doi/10.1073/pnas.1215854110
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http://dx.doi.org/10.1073/pnas.1215854110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3545770PMC
January 2013

TrkB and protein kinase Mζ regulate synaptic localization of PSD-95 in developing cortex.

J Neurosci 2011 Aug;31(33):11894-904

Departmens of Brain and Cognitive Science, McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.2190-11.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158490PMC
August 2011

A synaptic strategy for consolidation of convergent visuotopic maps.

Neuron 2011 Aug;71(4):710-24

McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.neuron.2011.06.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365514PMC
August 2011

Synaptic drive at developing synapses: transient upregulation of kainate receptors.

Dev Neurobiol 2010 Sep;70(11):737-50

McGovern Institute for Brain Research and Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1002/dneu.20807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945695PMC
September 2010

Postsynaptic BDNF-TrkB signaling in synapse maturation, plasticity, and disease.

Dev Neurobiol 2010 Apr;70(5):304-22

McGovern Institute for Brain Research, Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1002/dneu.20765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923204PMC
April 2010

Distinct roles of NR2A and NR2B cytoplasmic tails in long-term potentiation.

J Neurosci 2010 Feb;30(7):2676-85

Department of Basic Science, The Commonwealth Medical College, Scranton, Pennsylvania 18510, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.4022-09.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840640PMC
February 2010

Development of hemodynamic responses and functional connectivity in rat somatosensory cortex.

Nat Neurosci 2008 Jan 25;11(1):72-9. Epub 2007 Nov 25.

McGovern Institute for Brain Research, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1038/nn2017DOI Listing
January 2008

NR2A-/- mice lack long-term potentiation but retain NMDA receptor and L-type Ca2+ channel-dependent long-term depression in the juvenile superior colliculus.

J Neurosci 2007 Dec;27(50):13649-54

The McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.3153-07.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673614PMC
December 2007

BDNF induces transport of PSD-95 to dendrites through PI3K-AKT signaling after NMDA receptor activation.

Nat Neurosci 2007 Jun 21;10(6):702-11. Epub 2007 May 21.

Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139-4307, USA.

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http://dx.doi.org/10.1038/nn1903DOI Listing
June 2007

RNA interference of Xenopus NMDAR NR1 in vitro and in vivo.

J Neurosci Methods 2006 Apr 22;152(1-2):65-73. Epub 2005 Sep 22.

McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.jneumeth.2005.08.010DOI Listing
April 2006

Shining light on spike timing-dependent plasticity.

Neuron 2006 Apr;50(1):5-7

McGovern Institute for Brain Research, 46-4165 Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1016/j.neuron.2006.03.024DOI Listing
April 2006

Developmental period for N-methyl-D-aspartate (NMDA) receptor-dependent synapse elimination correlated with visuotopic map refinement.

J Comp Neurol 2006 Feb;494(5):738-51

McGovern Institute for Brain Research, Department of Biology, Cambridge, Massachusetts 02139-4307, USA.

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http://dx.doi.org/10.1002/cne.20841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605428PMC
February 2006

Microarray analysis of microRNA expression in the developing mammalian brain.

Genome Biol 2004 31;5(9):R68. Epub 2004 Aug 31.

Howard Hughes Medical Institute, Department of Biology and McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1186/gb-2004-5-9-r68DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC522875PMC
May 2005

NMDA receptor currents suppress synapse formation on sprouting axons in vivo.

J Neurosci 2005 Feb;25(5):1291-303

McGovern Institute for Brain Research, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.4063-04.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6725955PMC
February 2005

Retina-driven dephosphorylation of the NR2A subunit correlates with faster NMDA receptor kinetics at developing retinocollicular synapses.

J Neurosci 2004 Dec;24(49):11098-107

Interdepartmental Neuroscience Program, Yale University, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1207-04.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6730286PMC
December 2004

Post-transcriptional gene silencing in neurons.

Curr Opin Neurobiol 2004 Oct;14(5):654-9

Department of Biology, McGovern Institute for Brain Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1016/j.conb.2004.08.009DOI Listing
October 2004

Receptor compartmentalization and trafficking at glutamate synapses: a developmental proposal.

Trends Neurosci 2004 Jul;27(7):428-37

Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1016/j.tins.2004.05.010DOI Listing
July 2004

Eye opening rapidly induces synaptic potentiation and refinement.

Neuron 2004 Jul;43(2):237-49

Department of Biology, McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge 02139, USA.

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http://dx.doi.org/10.1016/j.neuron.2004.06.031DOI Listing
July 2004

Developmental loss of miniature N-methyl-D-aspartate receptor currents in NR2A knockout mice.

Proc Natl Acad Sci U S A 2003 Feb 27;100(3):1340-5. Epub 2003 Jan 27.

Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1073/pnas.0335786100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC298774PMC
February 2003

Eye opening induces a rapid dendritic localization of PSD-95 in central visual neurons.

Proc Natl Acad Sci U S A 2003 Feb 27;100(3):1334-9. Epub 2003 Jan 27.

Department of Biology, Center for Learning and Memory, McGovern Institute for Brain Research, and Howard Hughes Medical Institute, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139-4307, USA.

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http://dx.doi.org/10.1073/pnas.0335785100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC298773PMC
February 2003

Chronic NMDA receptor blockade from birth delays the maturation of NMDA currents, but does not affect AMPA/kainate currents.

J Neurophysiol 2003 Jan;89(1):57-68

Department of Biology, Department of Brain and Cognitive Science, and McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge 02139, USA.

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http://dx.doi.org/10.1152/jn.00049.2002DOI Listing
January 2003

Interaction between metabotropic and NMDA subtypes of glutamate receptors in sprout suppression at young synapses.

J Neurosci 2002 Jan;22(1):226-38

Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139-4307, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757613PMC
January 2002