Marta Pàez-Ribes

Galacto-conjugation of Navitoclax as an efficient strategy to increase senolytic specificity and reduce platelet toxicity.

Aging Cell 2020 04 31;19(4):e13142. Epub 2020 Mar 31.

CRUK Cambridge Centre Early Detection Programme, Department of Oncology, Hutchison/MRC Research Centre, University of Cambridge, Cambridge, UK.

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April 2020

Targeting senescent cells in translational medicine.

Authors:

Marta Paez-Ribes Estela González-Gualda Gary J Doherty Daniel Muñoz-Espín

EMBO Mol Med 2019 12 19;11(12):e10234. Epub 2019 Nov 19.

Department of Oncology, CRUK Cambridge Centre Early Detection Programme, Hutchison/MRC Research Centre, University of Cambridge, Cambridge, UK.

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December 2019

Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3.

Authors:

Michela Borghesan Juan Fafián-Labora Olga Eleftheriadou Paula Carpintero-Fernández Marta Paez-Ribes Gema Vizcay-Barrena Avital Swisa Dror Kolodkin-Gal Pilar Ximénez-Embún Robert Lowe Belen Martín-Martín Hector Peinado Javier Muñoz Roland A Fleck Yuval Dor Ittai Ben-Porath Anna Vossenkamper Daniel Muñoz-Espin Ana O'Loghlen

Cell Rep 2019 06;27(13):3956-3971.e6

Epigenetics & Cellular Senescence Group, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark Street, London E1 2AT, UK; Centre for Genomics and Child Health, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AT, UK. Electronic address:

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June 2019

Antitumor Effects of Anti-Semaphorin 4D Antibody Unravel a Novel Proinvasive Mechanism of Vascular-Targeting Agents.

Authors:

Iratxe Zuazo-Gaztelu Marta Pàez-Ribes Patricia Carrasco Laura Martín Adriana Soler Mar Martínez-Lozano Roser Pons Judith Llena Luis Palomero Mariona Graupera Oriol Casanovas

Cancer Res 2019 Oct 25;79(20):5328-5341. Epub 2019 Jun 25.

Tumor Angiogenesis Group, ProCURE Research Program, Catalan Institute of Oncology, OncoBell Program, IDIBELL, Barcelona, Spain.

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October 2019

Pre- and post-operative anti-PD-L1 plus anti-angiogenic therapies in mouse breast or renal cancer models of micro- or macro-metastatic disease.

Authors:

Florence T H Wu Ping Xu Annabelle Chow Shan Man Janna Krüger Kabir A Khan Marta Paez-Ribes Elizabeth Pham Robert S Kerbel

Br J Cancer 2019 01 30;120(2):196-206. Epub 2018 Nov 30.

Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.

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January 2019

A versatile drug delivery system targeting senescent cells.

Authors:

Daniel Muñoz-Espín Miguel Rovira Irene Galiana Cristina Giménez Beatriz Lozano-Torres Marta Paez-Ribes Susana Llanos Selim Chaib Maribel Muñoz-Martín Alvaro C Ucero Guillermo Garaulet Francisca Mulero Stephen G Dann Todd VanArsdale David J Shields Andrea Bernardos José Ramón Murguía Ramón Martínez-Máñez Manuel Serrano

EMBO Mol Med 2018 09;10(9)

Tumor Suppression Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain

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September 2018

Anti-oncostatin M antibody inhibits the pro-malignant effects of oncostatin M receptor overexpression in squamous cell carcinoma.

Authors:

Justyna A Kucia-Tran Valtteri Tulkki Cinzia G Scarpini Stephen Smith Maja Wallberg Marta Paez-Ribes Angela M Araujo Jan Botthoff Maria Feeney Katherine Hughes Maria M Caffarel Nicholas Coleman

J Pathol 2018 03 9;244(3):283-295. Epub 2018 Jan 9.

Department of Pathology, University of Cambridge, Cambridge, UK.

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March 2018

Aflibercept and Ang1 supplementation improve neoadjuvant or adjuvant chemotherapy in a preclinical model of resectable breast cancer.

Authors:

Florence T H Wu Marta Paez-Ribes Ping Xu Shan Man Elena Bogdanovic Gavin Thurston Robert S Kerbel

Sci Rep 2016 11 14;6:36694. Epub 2016 Nov 14.

Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.

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November 2016

Efficacy of Cotargeting Angiopoietin-2 and the VEGF Pathway in the Adjuvant Postsurgical Setting for Early Breast, Colorectal, and Renal Cancers.

Authors:

Florence T H Wu Shan Man Ping Xu Annabelle Chow Marta Paez-Ribes Christina R Lee Steven R Pirie-Shepherd Urban Emmenegger Robert S Kerbel

Cancer Res 2016 12 20;76(23):6988-7000. Epub 2016 Sep 20.

Department of Medical Biophysics, University of Toronto, Toronto, Canada.

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December 2016

Development of Patient Derived Xenograft Models of Overt Spontaneous Breast Cancer Metastasis: A Cautionary Note.

Authors:

Marta Paez-Ribes Shan Man Ping Xu Robert S Kerbel

PLoS One 2016 29;11(6):e0158034. Epub 2016 Jun 29.

Biological Sciences Platform, Sunnybrook Research Institute, Toronto, Canada.

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July 2017

Potential Proinvasive or Metastatic Effects of Preclinical Antiangiogenic Therapy Are Prevented by Concurrent Chemotherapy.

Authors:

Marta Paez-Ribes Shan Man Ping Xu Robert S Kerbel

Clin Cancer Res 2015 Dec 13;21(24):5488-98. Epub 2015 Jul 13.

Biologic Sciences Platform, Sunnybrook Research Institute, Toronto, Canada. Department of Medical Biophysics, University of Toronto, Toronto, Canada.

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December 2015

Postsurgical adjuvant or metastatic renal cell carcinoma therapy models reveal potent antitumor activity of metronomic oral topotecan with pazopanib.

Authors:

Christopher Jedeszko Marta Paez-Ribes Teresa Di Desidero Shan Man Christina R Lee Ping Xu Georg A Bjarnason Guido Bocci Robert S Kerbel

Sci Transl Med 2015 Apr;7(282):282ra50

Biological Sciences Platform, Sunnybrook Research Institute, Toronto, Ontario M4N 3M5, Canada. Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5S 2J7, Canada.

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April 2015