Marta E Alarcon-Riquelme

Marta E Alarcon-Riquelme

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Marta E Alarcon-Riquelme

Marta E Alarcon-Riquelme

Publications by authors named "Marta E Alarcon-Riquelme"

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An update on the genetics of systemic lupus erythematosus.

Curr Opin Rheumatol 2019 Nov;31(6):659-668

Unit of Chronic Inflammatory Diseases, Institute for Environmental Medicine IMM, Karolinska Institutet, Solna, Sweden.

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http://dx.doi.org/10.1097/BOR.0000000000000654DOI Listing
November 2019

Big data: the opportunity to think outside the discipline.

Nat Rev Rheumatol 2019 Nov;15(11):639-640

GENYO. Centre for Genomics and Oncological Research, Pfizer/University of Granada/Andalusian Regional Government, Granada, Spain.

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http://dx.doi.org/10.1038/s41584-019-0292-9DOI Listing
November 2019

Discovering new metabolite alterations in primary sjögren's syndrome in urinary and plasma samples using an HPLC-ESI-QTOF-MS methodology.

J Pharm Biomed Anal 2019 Nov 20:112999. Epub 2019 Nov 20.

Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Avd. Fuentenueva s/n, 18071, Granada, Spain; Research and Development of Functional Food Centre (CIDAF), Health Science Technological Park, Avd. del Conocimiento, nº 37, 18016, Granada, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2019.112999DOI Listing
November 2019

BANK1 interacts with TRAF6 and MyD88 in innate immune signaling in B cells.

Cell Mol Immunol 2019 Jun 26. Epub 2019 Jun 26.

Pfizer-University of Granada-Junta de Andalucía "Centre for Genomics and Oncological Research" (GENYO), Avenida de la Ilustración 114, 18016, Granada, Spain.

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http://dx.doi.org/10.1038/s41423-019-0254-9DOI Listing
June 2019

ImaGEO: integrative gene expression meta-analysis from GEO database.

Bioinformatics 2019 Mar;35(5):880-882

Bioinformatics Unit, GENYO Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government, PTS Granada, Granada, Spain.

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http://dx.doi.org/10.1093/bioinformatics/bty721DOI Listing
March 2019

New Attempts to Define and Clarify Lupus.

Curr Rheumatol Rep 2019 Feb 26;21(4):11. Epub 2019 Feb 26.

Medical Genomics, GENYO. Centre for Genomics and Oncological Research: Pfizer/University of Granada/Andalusian Regional Government, Av de la Ilustración 114, PTS, 18016, Granada, Spain.

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http://link.springer.com/10.1007/s11926-019-0810-4
Publisher Site
http://dx.doi.org/10.1007/s11926-019-0810-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394445PMC
February 2019

Exploring Impact of Rare Variation in Systemic Lupus Erythematosus by a Genome Wide Imputation Approach.

Front Immunol 2019 26;10:258. Epub 2019 Feb 26.

Unit of Chronic Inflammation, Institute for Environmental Medicine, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.3389/fimmu.2019.00258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399402PMC
February 2019

Urinary and plasma metabolite differences detected by HPLC-ESI-QTOF-MS in systemic sclerosis patients.

J Pharm Biomed Anal 2019 Jan 11;162:82-90. Epub 2018 Sep 11.

Research and Development of Functional Food Centre (CIDAF), Health Science Technological Park, Granada, Spain; Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Granada, Spain.

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http://dx.doi.org/10.1016/j.jpba.2018.09.021DOI Listing
January 2019

Stratification of Systemic Lupus Erythematosus Patients Into Three Groups of Disease Activity Progression According to Longitudinal Gene Expression.

Arthritis Rheumatol 2018 12 27;70(12):2025-2035. Epub 2018 Oct 27.

Centro de Genómica e Investigaciones Oncológicas Pfizer-Universidad de Granada-Junta de Andalucía, Granada, Spain, and Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1002/art.40653DOI Listing
December 2018

Epigenome-wide association studies for systemic autoimmune diseases: The road behind and the road ahead.

Clin Immunol 2018 11 29;196:21-33. Epub 2018 Mar 29.

Pfizer - University of Granada - Andalusian Government Center for Genomics and Oncological Research (GENYO), Granada, Spain; Unit of Inflammatory Chronic Diseases, Institute of Environmental Medicine, Karolinska Institutet, Solna, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2018.03.014DOI Listing
November 2018

A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus.

Hum Mol Genet 2018 07;27(13):2392-2404

Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1093/hmg/ddy140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005081PMC
July 2018

Corrigendum to "Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome" [Clin. Immunol. 168 (2016) 25-29].

Clin Immunol 2018 02 7;187:137-138. Epub 2017 Dec 7.

Arthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA; Department of Pathology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Department of Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Medical Service, Department of Veterans Affairs Medical Center, Oklahoma City, OK, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2017.11.012DOI Listing
February 2018

Moving towards a molecular taxonomy of autoimmune rheumatic diseases.

Nat Rev Rheumatol 2018 01;14(2):75-93

GENYO Centre for Genomics and Oncological Research: Pfizer - University of Granada - Andalusian Government, Avenida de la Ilustración 114, P.T.S., 18016 Granada, Spain.

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http://dx.doi.org/10.1038/nrrheum.2017.220DOI Listing
January 2018

Metagene projection characterizes GEN2.2 and CAL-1 as relevant human plasmacytoid dendritic cell models.

Bioinformatics 2017 Dec;33(23):3691-3695

Genomic Medicine Department, GENYO, Centre for Genomics and Oncological Research, Pfizer/University of Granada/Andalusian Regional Government, PTS 18016, Granada, Spain.

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http://dx.doi.org/10.1093/bioinformatics/btx502DOI Listing
December 2017

Effects of Amerindian Genetic Ancestry on Clinical Variables and Therapy in Patients with Rheumatoid Arthritis.

J Rheumatol 2017 Dec 1;44(12):1804-1812. Epub 2017 Nov 1.

From the Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, New York, USA; Departamento de Inmunología y Reumatología, Hospital General de Occidente y Universidad de Guadalajara, Zapopan; Unidad de Investigación "Dr. Mario Alvizouri Muñoz" Hospital General "Dr. Miguel Silva," Secretaría de Salud de Michoacán, Morelia; Servicio de Reumatología del Departamento de Medicina Interna, Facultad de Medicina y Hospital Universitario "Dr. José Eleuterio González," Universidad Autonoma de Nuevo León, Monterrey; Departamento de Reumatología, Hospital General de Culiacán, Culiacán; Unidad de Reumatología, Hospital General de México "Dr. Eduardo Liceaga"; Unidad de Biología Molecular y Medicina Genómica from Instituto de Investigaciones Biomédicas de la Universidad Nacional Autónoma de México, and Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico; Hospital Provincial de Rosario; Instituto Lucha Antipoliomielítica de Rosario (ILAR); Hospital Escuela Eva Perón, Granadero Baigorria; Hospital José Maria Cullen; Hospital J.B. Iturraspe, Santa Fe; Hospital San Martín, Paraná; Hospital Privado de Córdoba; Hospital Italiano de Córdoba; Instituto Reumatológico Strusberg, Córdoba; Hospital Cosme Argerich; Hospital Italiano de Buenos Aires; Organización Médica Integral; Centro de Educación Médica e Investigaciones Clínicas (CEMIC); Instituto de Rehabilitación Psicofísica (IREP); Hospital Bernardino Rivadavia; Hospital de Clínicas de Buenos Aires, Buenos Aires; H.I.G.A. San Martín, La Plata; H.I.G.A. Oscar E. Alende, Mar del Plata; Centro Medico Privado de Reumatología; FUNIPSE, San Miguel de Tucumán, Tucumán; Hospital Interzonal San Juan Bautista, Catamarca; Hospital G. Rawson, San Juan; Sanatorio Parque, Rosario, Argentina; Facultad Medicina Occidente, and Facultad de Medicina Campus Centro, Universidad de Chile, Santiago de Chile, Chile; Servicio de Reumatología, Hospital Nacional Guillermo Almenara I, EsSalud y Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú; GENYO, Centro Pfizer-Universidad de Granada-Junta de Andalucía de Genómica e Investigación Oncológica, Granada, Spain; Unit of Chronic Inflammatory Diseases, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.160485
Publisher Site
http://dx.doi.org/10.3899/jrheum.160485DOI Listing
December 2017

MetaGenyo: a web tool for meta-analysis of genetic association studies.

BMC Bioinformatics 2017 Dec 16;18(1):563. Epub 2017 Dec 16.

Bioinformatics Unit, Centre for Genomics and Oncological Research (GENYO), Granada, Spain.

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http://dx.doi.org/10.1186/s12859-017-1990-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732412PMC
December 2017

The TREX1 Dinosaur Bites the Brain through the LINE.

Cell Stem Cell 2017 09;21(3):287-288

Pfizer - University of Granada - Andalusian Government Center for Genomics and Oncological Research (GENYO), PTS, 18016, Granada, Spain; Unit for Chronic Inflammatory Diseases, Institute for Environmental Medicine, Karolinska Institute, Solna, 171 77, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2017.08.010DOI Listing
September 2017

BANK1 Regulates IgG Production in a Lupus Model by Controlling TLR7-Dependent STAT1 Activation.

PLoS One 2016 26;11(5):e0156302. Epub 2016 May 26.

Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, 73104, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0156302PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882053PMC
July 2017

Transancestral mapping and genetic load in systemic lupus erythematosus.

Authors:
Carl D Langefeld Hannah C Ainsworth Deborah S Cunninghame Graham Jennifer A Kelly Mary E Comeau Miranda C Marion Timothy D Howard Paula S Ramos Jennifer A Croker David L Morris Johanna K Sandling Jonas Carlsson Almlöf Eduardo M Acevedo-Vásquez Graciela S Alarcón Alejandra M Babini Vicente Baca Anders A Bengtsson Guillermo A Berbotto Marc Bijl Elizabeth E Brown Hermine I Brunner Mario H Cardiel Luis Catoggio Ricard Cervera Jorge M Cucho-Venegas Solbritt Rantapää Dahlqvist Sandra D'Alfonso Berta Martins Da Silva Iñigo de la Rúa Figueroa Andrea Doria Jeffrey C Edberg Emőke Endreffy Jorge A Esquivel-Valerio Paul R Fortin Barry I Freedman Johan Frostegård Mercedes A García Ignacio García de la Torre Gary S Gilkeson Dafna D Gladman Iva Gunnarsson Joel M Guthridge Jennifer L Huggins Judith A James Cees G M Kallenberg Diane L Kamen David R Karp Kenneth M Kaufman Leah C Kottyan László Kovács Helle Laustrup Bernard R Lauwerys Quan-Zhen Li Marco A Maradiaga-Ceceña Javier Martín Joseph M McCune David R McWilliams Joan T Merrill Pedro Miranda José F Moctezuma Swapan K Nath Timothy B Niewold Lorena Orozco Norberto Ortego-Centeno Michelle Petri Christian A Pineau Bernardo A Pons-Estel Janet Pope Prithvi Raj Rosalind Ramsey-Goldman John D Reveille Laurie P Russell José M Sabio Carlos A Aguilar-Salinas Hugo R Scherbarth Raffaella Scorza Michael F Seldin Christopher Sjöwall Elisabet Svenungsson Susan D Thompson Sergio M A Toloza Lennart Truedsson Teresa Tusié-Luna Carlos Vasconcelos Luis M Vilá Daniel J Wallace Michael H Weisman Joan E Wither Tushar Bhangale Jorge R Oksenberg John D Rioux Peter K Gregersen Ann-Christine Syvänen Lars Rönnblom Lindsey A Criswell Chaim O Jacob Kathy L Sivils Betty P Tsao Laura E Schanberg Timothy W Behrens Earl D Silverman Marta E Alarcón-Riquelme Robert P Kimberly John B Harley Edward K Wakeland Robert R Graham Patrick M Gaffney Timothy J Vyse

Nat Commun 2017 07 17;8:16021. Epub 2017 Jul 17.

Divisions of Genetics and Molecular Medicine and Immunology, Infection and Inflammatory Diseases, King's College London, Guy's Hospital, London SE1 9RT, UK.

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http://dx.doi.org/10.1038/ncomms16021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520018PMC
July 2017

SLE redefined on the basis of molecular pathways.

Best Pract Res Clin Rheumatol 2017 06 21;31(3):291-305. Epub 2017 Oct 21.

Pfizer - University of Granada - Andalusian Government Center for Genomics and Oncological Research (GENYO), Av de la Ilustración 114, PTS, 18016, Granada, Spain; Unit of Inflammatory Chronic Diseases, Institute of Environmental Medicine, Karolinska Institutet, Solna, 17777, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.berh.2017.09.006DOI Listing
June 2017

Omics studies: their use in diagnosis and reclassification of SLE and other systemic autoimmune diseases.

Rheumatology (Oxford) 2017 04;56(suppl_1):i78-i87

Parque Tecnológico de la Salud, Medical Genomics, Centre Pfizer, University of Granada, Andalusian Regional Government for Genomics and Oncological Research, Granada, Spain.

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http://dx.doi.org/10.1093/rheumatology/kew339DOI Listing
April 2017

Overexpression of the Cytokine BAFF and Autoimmunity Risk.

N Engl J Med 2017 04;376(17):1615-1626

From Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche Monserrato (M.S., V.O., M.L.I., M. Pitzalis, M. Pala, C.S., V.F., M.F., M. Deiana, I.A., E.P., A. Mulas, M.G.P., M. Lobina, S.L., Mara Marongiu, V.S., Michele Marongiu, G.S., F.B., A. Maschio, F.D., M. Dei, F.V., S.O., A.A., M.B.W., A. Meloni, S. Sanna, E.F., M.Z., F.C.), Center for Advanced Studies, Research, and Development in Sardinia, Parco Scientifico e Tecnologico della Sardegna (I.Z., M.F., R.C., G. Cuccuru), Struttura Complessa Disciplina di Ematologia e Centro Trapianto Cellule Staminali Emopoietiche Wilma Deplano, Ospedale Oncologico di Riferimento Regionale Armando Businco (M. Pani), Dipartimento di Sanità Pubblica, Medicina Clinica e Molecolare, Università di Cagliari (E.C., J.F., G. Coghe, L.L., G. Fenu), Azienda Ospedaliera Brotzu, S.C. Neurologia (P.F., M. Melis), Division of Rheumatology, University and University Hospital of Cagliari (M. Piga, A. Mathieu), Department of Medical Sciences M. Aresu, University of Cagliari (D.F., S.D.G., M.G.M.), Azienda Ospedaliera Brotzu, U.S. Gastroenterologia Pediatrica Ospedale Pediatrico Microcitemico A. Cao (M.C.), and Nephrology, Dialysis, and Transplantation Unit, Giuseppe Brotzu Hospital (A.P.), Cagliari, Dipartimento di Scienze Biomediche, Università degli Studi di Sassari (M.F., F.P., F.C.), Unit of Neurology, Department of Clinical and Experimental Medicine, University of Sassari (G. Farina, G.R.), and Servizio Trasfusionale (M.A.S.) and Clinica Medica (A.D.), Azienda Ospedaliero Universitaria di Sassari, Sassari, Neurology B, Department of Neurological, Biomedical, and Movement Sciences, University of Verona, Verona (G. Farina), Department of Health Sciences, Interdisciplinary Research Center of Autoimmune Diseases, University of Eastern Piedmont, Novara (N.B., S.D.), SC Neurologia, Dipartimento di Scienze Mediche, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS) Casa Sollievo della Sofferenza, San Giovanni Rotondo (M. Leone), Don C. Gnocchi Foundation IRCCS (F.R.G.), and Referral Center for Systemic Autoimmune Diseases Fondazione IRCCS Cá Granda Ospedale Maggiore Policlinico and University of Milan (M. Marchini), Milan, and Dipartimento di Scienze Cliniche e Molecolari, Università Politecnica delle Marche e Ospedali Riuniti, Ancona (M.G.D.) - all in Italy; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore (M.L.I., M.G., D.S.); the Department of Clinical Neurosciences (M.B., S. Sawcer) and JDRF-Wellcome Trust Diabetes and Inflammation Laboratory, National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research (J.A.T.), University of Cambridge, Cambridge, United Kingdom; Department of Clinical Neuroscience, Karolinska Institutet at Karolinska University Hospital Solna (I.K., I.L.B., T.O., J.H.), Institute of Environmental Medicine (L.A.) and Institute of Environmental Medicine, Unit of Immunology and Chronic Disease (M.E.A.R.), Karolinska Institute, and Center for Occupational and Environmental Medicine, Stockholm County Council (L.A.), Stockholm; Department of Functional Biology, University of Oviedo, Oviedo (A.S.), Rheumatology Department, Hospital Universitario 12 de Octubre, Madrid (P.E.C.), Department of Internal Medicine, Hospital Universitario Virgen del Rocío, Seville (M.J.C.-P.), Laboratorio de Investigacion 10 and Rheumatology Unit, Instituto de Investigacion Sanitaria-Hospital Clinico Universitario de Santiago, Santiago de Compostela (A.G.), and Centro de Genómica e Investigación Oncológica, Pfizer-Universidad de Granada-Junta de Andalucía, Granada (M.E.A.R.) - all in Spain; Department of Human Genetics, University of Chicago, Chicago (J.H.M., J.N.); Centro Hospitalar do Porto-Hospital Santo Antonio and Unit for Multidisciplinary Research in Biomedicine-Unidade Multidisciplinar de Investigação Biomédica, Porto, Portugal (B.M.S.); Departments of Pathology and Genetics, Stanford University, Stanford, CA (S.B.M.); and Center for Statistical Genetics, University of Michigan, Ann Arbor (G.R.A.).

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http://dx.doi.org/10.1056/NEJMoa1610528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605835PMC
April 2017

Support for phosphoinositol 3 kinase and mTOR inhibitors as treatment for lupus using in-silico drug-repurposing analysis.

Arthritis Res Ther 2017 03 11;19(1):54. Epub 2017 Mar 11.

Area of Medical Genomics, Pfizer-University of Granada-Andalusian Government Centre for Genomics and Oncological Research (GENYO), Avda. de la Ilustración 114, PTS-18016, Granada, Spain.

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http://dx.doi.org/10.1186/s13075-017-1263-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5346251PMC
March 2017

Systemic Lupus Erythematosus in 2016: Gene expression profiling comes closer to the clinic.

Nat Rev Rheumatol 2017 02 5;13(2):69-70. Epub 2017 Jan 5.

GENYO (Centre for Genomics and Oncological Research), P. T. Ciencias de la Salud, Avenida de la Ilustración 114, 18016 Granada, Spain; and at the Unit for Chronic Inflammatory Diseases, Institute for Environmental Medicine, Karolinska Institutet, 171 67 Stockholm, Sweden.

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http://dx.doi.org/10.1038/nrrheum.2016.211DOI Listing
February 2017

The genetic basis of systemic lupus erythematosus: What are the risk factors and what have we learned.

J Autoimmun 2016 11 10;74:161-175. Epub 2016 Aug 10.

Center for Genomics and Oncological Research, GENYO, Pfizer/University of Granada/Andalusian Government, PTS, Granada, 18016, Spain; Institute of Environmental Medicine, Karolinska Institute, Stockholm, 171 67, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2016.08.001DOI Listing
November 2016

Genetics of systemic lupus erythematosus and Sjögren's syndrome: an update.

Curr Opin Rheumatol 2016 09;28(5):506-14

aGENYO, Center for Genomics and Oncological Research Pfizer/University of Granada/Andalusian Regional Government, Parque Tecnológico de la Salud, Granada, Spain bUnit of Chronic Inflammatory Diseases, Institute for Environmental Medicine IMM, Karolinska Institutet, Solna, Sweden.

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http://dx.doi.org/10.1097/BOR.0000000000000310DOI Listing
September 2016

Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome.

Clin Immunol 2016 07 22;168:25-29. Epub 2016 Apr 22.

Arthritis & Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA; Department of Pathology, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Department of Medicine, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA; Medical Service, Department of Veterans Affairs Medical Center, Oklahoma City, OK, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2016.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940221PMC
July 2016

X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome.

Arthritis Rheumatol 2016 05;68(5):1290-1300

College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

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http://dx.doi.org/10.1002/art.39560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019501PMC
May 2016

Intronic variants in the NFKB1 gene may influence hearing forecast in patients with unilateral sensorineural hearing loss in Meniere's disease.

PLoS One 2014 14;9(11):e112171. Epub 2014 Nov 14.

Otology & Neurotology Group CTS495, Department of Genomic Medicine- Centro de Genómica e Investigación Oncológica - Pfizer/Universidad de Granada/Junta de Andalucía (GENYO), Granada, Spain; Department of Otolaryngology, Hospital de Poniente, El Ejido, Almería, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0112171PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232390PMC
July 2015

Concordance of increased B1 cell subset and lupus phenotypes in mice and humans is dependent on BLK expression levels.

J Immunol 2015 Jun 13;194(12):5692-702. Epub 2015 May 13.

Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104; Centre for Genomics and Oncological Research (GENYO), Pfizer-University of Granada-Andalusian Regional Government, Health Sciences Technology Park, Granada 18016, Spain;

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http://dx.doi.org/10.4049/jimmunol.1402736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458437PMC
June 2015

Towards the taxonomy of human disease.

Nat Rev Drug Discov 2015 02;14(2):75-6

New Medicines, UCB, 208 Bath Road, Slough, SL1 4EN, UK.

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http://dx.doi.org/10.1038/nrd4537DOI Listing
February 2015

Epigenomic elements enriched in the promoters of autoimmunity susceptibility genes.

Epigenetics 2014 Feb 8;9(2):276-85. Epub 2013 Nov 8.

Oklahoma Medical Research Foundation; Arthritis and Clinical Immunology Research Program; Oklahoma City, OK USA; GENYO; Centre for Genomics and Oncological Research; Pfizer; University of Granada; Andalusian Regional Government; Granada, Spain.

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http://dx.doi.org/10.4161/epi.27021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3962538PMC
February 2014

BANK1 and BLK act through phospholipase C gamma 2 in B-cell signaling.

PLoS One 2013 26;8(3):e59842. Epub 2013 Mar 26.

Centro de Genómica e Investigación Oncológica, Pfizer-Universidad de Granada-Junta de Andalucía, Granada, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0059842PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608554PMC
January 2014

BANK1 controls CpG-induced IL-6 secretion via a p38 and MNK1/2/eIF4E translation initiation pathway.

J Immunol 2013 Dec 13;191(12):6110-6. Epub 2013 Nov 13.

Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK 73104.

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http://dx.doi.org/10.4049/jimmunol.1301203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858538PMC
December 2013

Genes, epigenetic regulation and environmental factors: which is the most relevant in developing autoimmune diseases?

Autoimmun Rev 2012 Jun 25;11(8):604-9. Epub 2011 Oct 25.

Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.autrev.2011.10.022DOI Listing
June 2012

Recent findings on genetics of systemic autoimmune diseases.

Curr Opin Immunol 2010 Dec 20;22(6):698-705. Epub 2010 Oct 20.

Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Dag Hammarsjölds väg 20, 751 85 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.coi.2010.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997852PMC
December 2010