Publications by authors named "Mart Loog"

33Publications

A new linear cyclin docking motif that mediates exclusively S-phase CDK-specific signaling.

EMBO J 2020 Nov 19:e105839. Epub 2020 Nov 19.

Institute of Technology, University of Tartu, Tartu, Estonia.

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http://dx.doi.org/10.15252/embj.2020105839DOI Listing
November 2020

The sequence at Spike S1/S2 site enables cleavage by furin and phospho-regulation in SARS-CoV2 but not in SARS-CoV1 or MERS-CoV.

Sci Rep 2020 10 9;10(1):16944. Epub 2020 Oct 9.

Institute of Technology, University of Tartu, 50411, Tartu, Estonia.

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http://dx.doi.org/10.1038/s41598-020-74101-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547067PMC
October 2020

Comprehensive Analysis of G1 Cyclin Docking Motif Sequences that Control CDK Regulatory Potency In Vivo.

Curr Biol 2020 Nov 24;30(22):4454-4466.e5. Epub 2020 Sep 24.

Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2020.08.099DOI Listing
November 2020

Detection of Multisite Phosphorylation of Intrinsically Disordered Proteins Using Quantitative Mass-Spectrometry.

Methods Mol Biol 2020 ;2141:819-833

Institute of Technology, University of Tartu, Tartu, Estonia.

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http://dx.doi.org/10.1007/978-1-0716-0524-0_42DOI Listing
January 2020

Detection of Multisite Phosphorylation of Intrinsically Disordered Proteins Using Phos-tag SDS-PAGE.

Methods Mol Biol 2020 ;2141:779-792

Institute of Technology, University of Tartu, Tartu, Estonia.

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http://dx.doi.org/10.1007/978-1-0716-0524-0_40DOI Listing
January 2020

Multisite phosphorylation code of CDK.

Nat Struct Mol Biol 2019 07 1;26(7):649-658. Epub 2019 Jul 1.

Institute of Technology, University of Tartu, Tartu, Estonia.

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http://dx.doi.org/10.1038/s41594-019-0256-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614033PMC
July 2019

Synthetic-Evolution Reveals Narrow Paths to Regulation of the Mitotic Kinesin-5 Cin8.

Int J Biol Sci 2019 2;15(6):1125-1138. Epub 2019 May 2.

Department of Chemistry and Ilse Katz Institute for Nanoscale Science and Technology, Ben-Gurion University of the Negev, PO Box 653, Beer-Sheva, 84105, Israel.

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http://dx.doi.org/10.7150/ijbs.30543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6567808PMC
April 2020

Cyclin-Specific Docking Mechanisms Reveal the Complexity of M-CDK Function in the Cell Cycle.

Mol Cell 2019 07 14;75(1):76-89.e3. Epub 2019 May 14.

Institute of Technology, University of Tartu, Tartu 50411, Estonia. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.04.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620034PMC
July 2019

How the cell cycle clock ticks.

Mol Biol Cell 2019 01;30(2):169-172

Institute of Technology, University of Tartu, 50411 Tartu, Estonia.

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http://dx.doi.org/10.1091/mbc.E18-05-0272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589557PMC
January 2019

A Clb/Cdk1-mediated regulation of Fkh2 synchronizes expression in the budding yeast cell cycle.

NPJ Syst Biol Appl 2017 6;3. Epub 2017 Mar 6.

Synthetic Systems Biology and Nuclear Organization, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, 1098 XH The Netherlands.

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http://dx.doi.org/10.1038/s41540-017-0008-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460246PMC
March 2017

Three Cdk1 sites in the kinesin-5 Cin8 catalytic domain coordinate motor localization and activity during anaphase.

Cell Mol Life Sci 2017 09 28;74(18):3395-3412. Epub 2017 Apr 28.

Department of Chemistry and Ilse Katz Institute for Nanoscale Science and Technology, Ben-Gurion University of the Negev, PO Box 653, 84105, Beer-Sheva, Israel.

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http://dx.doi.org/10.1007/s00018-017-2523-zDOI Listing
September 2017

A docking interface in the cyclin Cln2 promotes multi-site phosphorylation of substrates and timely cell-cycle entry.

Curr Biol 2015 Feb 22;25(3):316-325. Epub 2015 Jan 22.

Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2014.11.069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318751PMC
February 2015

Multistep phosphorylation systems: tunable components of biological signaling circuits.

Mol Biol Cell 2014 Nov;25(22):3456-60

Institute of Technology, University of Tartu, 50411 Tartu, Estonia

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http://dx.doi.org/10.1091/mbc.E14-02-0774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230602PMC
November 2014

Protein kinase inhibitor SU6668 attenuates positive regulation of Gli proteins in cancer and multipotent progenitor cells.

Biochim Biophys Acta 2014 Apr 10;1843(4):703-14. Epub 2014 Jan 10.

Department of Gene Technology, Tallinn University of Technology, Akadeemia tee 15, Tallinn 12618, Estonia.

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http://dx.doi.org/10.1016/j.bbamcr.2014.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946003PMC
April 2014

Cks confers specificity to phosphorylation-dependent CDK signaling pathways.

Nat Struct Mol Biol 2013 Dec 3;20(12):1407-14. Epub 2013 Nov 3.

1] Department of Chemistry and Biochemistry, University of California, Santa Cruz, Santa Cruz, California, USA. [2].

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http://dx.doi.org/10.1038/nsmb.2707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242096PMC
December 2013

Multisite phosphorylation networks as signal processors for Cdk1.

Nat Struct Mol Biol 2013 Dec 3;20(12):1415-24. Epub 2013 Nov 3.

Institute of Technology, University of Tartu, Tartu, Estonia.

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http://dx.doi.org/10.1038/nsmb.2706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855452PMC
December 2013

Kinetics of acrylodan-labelled cAMP-dependent protein kinase catalytic subunit denaturation.

Protein J 2013 Oct;32(7):519-25

Institute of Chemistry, University of Tartu, Tartu, Estonia.

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http://dx.doi.org/10.1007/s10930-013-9511-4DOI Listing
October 2013

Multiple Pho85-dependent mechanisms control G1 cyclin abundance in response to nutrient stress.

Mol Cell Biol 2013 Apr 4;33(7):1270-2. Epub 2013 Feb 4.

Institute of Technology, University of Tartu, Tartu, Estonia.

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http://dx.doi.org/10.1128/MCB.00086-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624275PMC
April 2013

Double-negative feedback between S-phase cyclin-CDK and CKI generates abruptness in the G1/S switch.

Front Physiol 2012 6;3:459. Epub 2012 Dec 6.

Institute of Technology, University of Tartu Tartu, Estonia.

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http://dx.doi.org/10.3389/fphys.2012.00459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515773PMC
December 2012

Probing L-pyruvate kinase regulatory phosphorylation site by mutagenesis.

Protein J 2012 Oct;31(7):592-7

Institute of Chemistry, University of Tartu, 14a Ravila Str, Tartu, 50411, Estonia.

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http://dx.doi.org/10.1007/s10930-012-9438-1DOI Listing
October 2012

Cdk1: a kinase with changing substrate specificity.

Cell Cycle 2011 Nov 1;10(21):3625-6. Epub 2011 Nov 1.

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http://dx.doi.org/10.4161/cc.10.21.17854DOI Listing
November 2011

Cascades of multisite phosphorylation control Sic1 destruction at the onset of S phase.

Nature 2011 Oct 12;480(7375):128-31. Epub 2011 Oct 12.

Institute of Technology, University of Tartu, Tartu 50411, Estonia.

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http://dx.doi.org/10.1038/nature10560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228899PMC
October 2011

Phospho-regulation of kinesin-5 during anaphase spindle elongation.

J Cell Sci 2011 Mar;124(Pt 6):873-8

Department of Clinical Biochemistry, Ben-Gurion University of the Negev, PO Box 653, Beer-Sheva, 84105, Israel.

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http://dx.doi.org/10.1242/jcs.077396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048887PMC
March 2011

Ozone-triggered rapid stomatal response involves the production of reactive oxygen species, and is controlled by SLAC1 and OST1.

Plant J 2010 May 1;62(3):442-53. Epub 2010 Feb 1.

Division of Plant Biology, Department of Biosciences, University of Helsinki, PO Box 65 (Viikinkaari 1), FI-00014 Helsinki, Finland.

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http://dx.doi.org/10.1111/j.1365-313X.2010.04159.xDOI Listing
May 2010

Screening for the optimal specificity profile of protein kinase C using electrospray mass-spectrometry.

J Biomol Screen 2005 Jun;10(4):320-8

Department of Medical Biochemistry and Microbiology, Uppsala University, 75123 Uppsala, Sweden.

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http://dx.doi.org/10.1177/1087057104274353DOI Listing
June 2005

Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates.

Nature 2005 Mar;434(7029):104-8

Department of Physiology, University of California, San Francisco, California 94143-2200, USA.

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http://dx.doi.org/10.1038/nature03329DOI Listing
March 2005

Comparison of cAMP-dependent protein kinase substrate specificity in reaction with proteins and synthetic peptides.

Biochim Biophys Acta 2005 Mar 28;1747(2):261-6. Epub 2004 Dec 28.

Department of Medical Biochemistry and Microbiology, University of Uppsala, S-75 123 Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.bbapap.2004.11.016DOI Listing
March 2005