Mart Kals

Mart Kals

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Mart Kals

Mart Kals

Publications by authors named "Mart Kals"

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Translating genotype data of 44,000 biobank participants into clinical pharmacogenetic recommendations: challenges and solutions.

Genet Med 2019 06 16;21(6):1345-1354. Epub 2018 Oct 16.

Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.

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http://dx.doi.org/10.1038/s41436-018-0337-5DOI Listing
June 2019

Heart rate reduction decreases central blood pressure in sick sinus syndrome patients with a permanent cardiac pacemaker.

J Hum Hypertens 2018 May 27;32(5):377-384. Epub 2018 Mar 27.

Department of Cardiology, Institute of Clinical Medicine, University of Tartu, 8 Puusepa Street, Tartu, 51014, Estonia.

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http://www.nature.com/articles/s41371-018-0051-4
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http://dx.doi.org/10.1038/s41371-018-0051-4DOI Listing
May 2018

Exome analysis in an Estonian multiplex family with neural tube defects-a case report.

Childs Nerv Syst 2017 Sep 18;33(9):1575-1581. Epub 2017 Jul 18.

Estonian Genome Center, University of Tartu, Riia 23b, 51010, Tartu, Estonia.

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http://dx.doi.org/10.1007/s00381-017-3491-1DOI Listing
September 2017

The Prevalence of PMM2-CDG in Estonia Based on Population Carrier Frequencies and Diagnosed Patients.

JIMD Rep 2018 7;39:13-17. Epub 2017 Jul 7.

Department of Clinical Genetics, United Laboratories, Tartu University Hospital, Tartu, Estonia.

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http://link.springer.com/10.1007/8904_2017_41
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http://dx.doi.org/10.1007/8904_2017_41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953896PMC
July 2017

Structured education can improve primary-care management of headache: the first empirical evidence, from a controlled interventional study.

J Headache Pain 2016 11;17:24. Epub 2016 Mar 11.

Department of Neuroscience, Norwegian University of Science and Technology, Edvard Griegs Gate, Trondheim, NO-7489, Norway.

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http://dx.doi.org/10.1186/s10194-016-0613-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4788653PMC
October 2016

Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.

Authors:
Padhraig Gormley Verneri Anttila Bendik S Winsvold Priit Palta Tonu Esko Tune H Pers Kai-How Farh Ester Cuenca-Leon Mikko Muona Nicholas A Furlotte Tobias Kurth Andres Ingason George McMahon Lannie Ligthart Gisela M Terwindt Mikko Kallela Tobias M Freilinger Caroline Ran Scott G Gordon Anine H Stam Stacy Steinberg Guntram Borck Markku Koiranen Lydia Quaye Hieab H H Adams Terho Lehtimäki Antti-Pekka Sarin Juho Wedenoja David A Hinds Julie E Buring Markus Schürks Paul M Ridker Maria Gudlaug Hrafnsdottir Hreinn Stefansson Susan M Ring Jouke-Jan Hottenga Brenda W J H Penninx Markus Färkkilä Ville Artto Mari Kaunisto Salli Vepsäläinen Rainer Malik Andrew C Heath Pamela A F Madden Nicholas G Martin Grant W Montgomery Mitja I Kurki Mart Kals Reedik Mägi Kalle Pärn Eija Hämäläinen Hailiang Huang Andrea E Byrnes Lude Franke Jie Huang Evie Stergiakouli Phil H Lee Cynthia Sandor Caleb Webber Zameel Cader Bertram Muller-Myhsok Stefan Schreiber Thomas Meitinger Johan G Eriksson Veikko Salomaa Kauko Heikkilä Elizabeth Loehrer Andre G Uitterlinden Albert Hofman Cornelia M van Duijn Lynn Cherkas Linda M Pedersen Audun Stubhaug Christopher S Nielsen Minna Männikkö Evelin Mihailov Lili Milani Hartmut Göbel Ann-Louise Esserlind Anne Francke Christensen Thomas Folkmann Hansen Thomas Werge Jaakko Kaprio Arpo J Aromaa Olli Raitakari M Arfan Ikram Tim Spector Marjo-Riitta Järvelin Andres Metspalu Christian Kubisch David P Strachan Michel D Ferrari Andrea C Belin Martin Dichgans Maija Wessman Arn M J M van den Maagdenberg John-Anker Zwart Dorret I Boomsma George Davey Smith Kari Stefansson Nicholas Eriksson Mark J Daly Benjamin M Neale Jes Olesen Daniel I Chasman Dale R Nyholt Aarno Palotie

Nat Genet 2016 09;48(10):1296

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http://dx.doi.org/10.1038/ng1016-1296cDOI Listing
September 2016

Single base resolution analysis of 5-hydroxymethylcytosine in 188 human genes: implications for hepatic gene expression.

Nucleic Acids Res 2016 08 29;44(14):6756-69. Epub 2016 Apr 29.

Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Nanna Svartz väg 2, 17177 Stockholm, Sweden.

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http://dx.doi.org/10.1093/nar/gkw316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001587PMC
August 2016

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.

Authors:
Padhraig Gormley Verneri Anttila Bendik S Winsvold Priit Palta Tonu Esko Tune H Pers Kai-How Farh Ester Cuenca-Leon Mikko Muona Nicholas A Furlotte Tobias Kurth Andres Ingason George McMahon Lannie Ligthart Gisela M Terwindt Mikko Kallela Tobias M Freilinger Caroline Ran Scott G Gordon Anine H Stam Stacy Steinberg Guntram Borck Markku Koiranen Lydia Quaye Hieab H H Adams Terho Lehtimäki Antti-Pekka Sarin Juho Wedenoja David A Hinds Julie E Buring Markus Schürks Paul M Ridker Maria Gudlaug Hrafnsdottir Hreinn Stefansson Susan M Ring Jouke-Jan Hottenga Brenda W J H Penninx Markus Färkkilä Ville Artto Mari Kaunisto Salli Vepsäläinen Rainer Malik Andrew C Heath Pamela A F Madden Nicholas G Martin Grant W Montgomery Mitja I Kurki Mart Kals Reedik Mägi Kalle Pärn Eija Hämäläinen Hailiang Huang Andrea E Byrnes Lude Franke Jie Huang Evie Stergiakouli Phil H Lee Cynthia Sandor Caleb Webber Zameel Cader Bertram Muller-Myhsok Stefan Schreiber Thomas Meitinger Johan G Eriksson Veikko Salomaa Kauko Heikkilä Elizabeth Loehrer Andre G Uitterlinden Albert Hofman Cornelia M van Duijn Lynn Cherkas Linda M Pedersen Audun Stubhaug Christopher S Nielsen Minna Männikkö Evelin Mihailov Lili Milani Hartmut Göbel Ann-Louise Esserlind Anne Francke Christensen Thomas Folkmann Hansen Thomas Werge Jaakko Kaprio Arpo J Aromaa Olli Raitakari M Arfan Ikram Tim Spector Marjo-Riitta Järvelin Andres Metspalu Christian Kubisch David P Strachan Michel D Ferrari Andrea C Belin Martin Dichgans Maija Wessman Arn M J M van den Maagdenberg John-Anker Zwart Dorret I Boomsma George Davey Smith Kari Stefansson Nicholas Eriksson Mark J Daly Benjamin M Neale Jes Olesen Daniel I Chasman Dale R Nyholt Aarno Palotie

Nat Genet 2016 08 20;48(8):856-66. Epub 2016 Jun 20.

Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://biorxiv.org/content/biorxiv/early/2015/11/02/030288.f
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http://dx.doi.org/10.1038/ng.3598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5331903PMC
August 2016

Age- and sex-specific causal effects of adiposity on cardiovascular risk factors.

Diabetes 2015 May 23;64(5):1841-52. Epub 2015 Feb 23.

Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, U.K.

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http://diabetes.diabetesjournals.org/content/64/5/1841.full.
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http://diabetes.diabetesjournals.org/lookup/doi/10.2337/db14
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http://dx.doi.org/10.2337/db14-0988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407863PMC
May 2015

Adiposity as a cause of cardiovascular disease: a Mendelian randomization study.

Int J Epidemiol 2015 Apr 27;44(2):578-86. Epub 2015 May 27.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, Molecular Epidemiology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden, Estonian Genome Center, University of Tartu, Tartu, Estonia, Department of Biological Psychology, VU University Amsterdam, Amsterdam, The Netherlands, EMGO Institute for Health and Care Research, Amsterdam, The Netherlands, Institute of Mathematical Statistics, University of Tartu, Tartu, Estonia, Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands, Netherlands Consortium for Healthy Ageing, Netherlands Genomics Initiative, Leiden, The Netherlands, Department of Genetic Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands, Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland, National Institute for Health and Welfare, Helsinki, Finland, Department of Neurology, and Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands, Inspectorate for Health Care, The Hague, The Netherlands, Queensland Brain Institute, University of Queensland, Brisbane, QLD, Australia, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia, Institute of Genetic Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany, Division of Epidemiology, Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, UK, Center for Life Course and Systems Epidemiology, University of Oulu, Oulu, Finland, Department of Chronic Disease Prevention, National Institute for Health and Welfare, Turku, Finland, Department of Children, Young People and Families, National Institute for Health and Welfare, Oulu, Finland, MRC Health Protection Agency (HPE) Centre for Environment and Health, Imperial College London, London, UK, Unit of Primary Care, Oulu University Hospital, Oulu, Finland, Hjelt Institute, University of Helsinki,

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http://dx.doi.org/10.1093/ije/dyv094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553708PMC
April 2015

CDH13 promoter SNPs with pleiotropic effect on cardiometabolic parameters represent methylation QTLs.

Hum Genet 2015 Mar 28;134(3):291-303. Epub 2014 Dec 28.

Human Molecular Genetics Group, Institute of Molecular and Cell Biology, University of Tartu, Riia St. 23, 51010, Tartu, Estonia.

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http://dx.doi.org/10.1007/s00439-014-1521-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4318987PMC
March 2015

Coffin-Siris Syndrome with obesity, macrocephaly, hepatomegaly and hyperinsulinism caused by a mutation in the ARID1B gene.

Eur J Hum Genet 2014 Nov 26;22(11):1327-9. Epub 2014 Feb 26.

1] Department of Paediatrics, University of Tartu, Tartu, Estonia [2] United Laboratories, Department of Genetics, Tartu University Hospital, Tartu, Estonia.

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http://dx.doi.org/10.1038/ejhg.2014.25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200437PMC
November 2014

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis.

Authors:
Tove Fall Sara Hägg Reedik Mägi Alexander Ploner Krista Fischer Momoko Horikoshi Antti-Pekka Sarin Gudmar Thorleifsson Claes Ladenvall Mart Kals Maris Kuningas Harmen H M Draisma Janina S Ried Natalie R van Zuydam Ville Huikari Massimo Mangino Emily Sonestedt Beben Benyamin Christopher P Nelson Natalia V Rivera Kati Kristiansson Huei-Yi Shen Aki S Havulinna Abbas Dehghan Louise A Donnelly Marika Kaakinen Marja-Liisa Nuotio Neil Robertson Renée F A G de Bruijn M Arfan Ikram Najaf Amin Anthony J Balmforth Peter S Braund Alexander S F Doney Angela Döring Paul Elliott Tõnu Esko Oscar H Franco Solveig Gretarsdottir Anna-Liisa Hartikainen Kauko Heikkilä Karl-Heinz Herzig Hilma Holm Jouke Jan Hottenga Elina Hyppönen Thomas Illig Aaron Isaacs Bo Isomaa Lennart C Karssen Johannes Kettunen Wolfgang Koenig Kari Kuulasmaa Tiina Laatikainen Jaana Laitinen Cecilia Lindgren Valeriya Lyssenko Esa Läärä Nigel W Rayner Satu Männistö Anneli Pouta Wolfgang Rathmann Fernando Rivadeneira Aimo Ruokonen Markku J Savolainen Eric J G Sijbrands Kerrin S Small Jan H Smit Valgerdur Steinthorsdottir Ann-Christine Syvänen Anja Taanila Martin D Tobin Andre G Uitterlinden Sara M Willems Gonneke Willemsen Jacqueline Witteman Markus Perola Alun Evans Jean Ferrières Jarmo Virtamo Frank Kee David-Alexandre Tregouet Dominique Arveiler Philippe Amouyel Marco M Ferrario Paolo Brambilla Alistair S Hall Andrew C Heath Pamela A F Madden Nicholas G Martin Grant W Montgomery John B Whitfield Antti Jula Paul Knekt Ben Oostra Cornelia M van Duijn Brenda W J H Penninx George Davey Smith Jaakko Kaprio Nilesh J Samani Christian Gieger Annette Peters H Erich Wichmann Dorret I Boomsma Eco J C de Geus TiinaMaija Tuomi Chris Power Christopher J Hammond Tim D Spector Lars Lind Marju Orho-Melander Colin Neil Alexander Palmer Andrew D Morris Leif Groop Marjo-Riitta Järvelin Veikko Salomaa Erkki Vartiainen Albert Hofman Samuli Ripatti Andres Metspalu Unnur Thorsteinsdottir Kari Stefansson Nancy L Pedersen Mark I McCarthy Erik Ingelsson Inga Prokopenko

PLoS Med 2013 25;10(6):e1001474. Epub 2013 Jun 25.

Molecular Epidemiology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1371/journal.pmed.1001474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692470PMC
March 2014

Preoperative corticosteroid injections are associated with worse long-term outcome of surgical carpal tunnel release.

Acta Orthop 2014 Feb 29;85(1):102-6. Epub 2013 Nov 29.

Faculty of Medicine , Tartu University Hospital, Tartu , Estonia .

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http://dx.doi.org/10.3109/17453674.2013.867781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3940985PMC
February 2014

In-solution hybrid capture of bisulfite-converted DNA for targeted bisulfite sequencing of 174 ADME genes.

Nucleic Acids Res 2013 Apr 15;41(6):e72. Epub 2013 Jan 15.

Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm 17177, Sweden.

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https://academic.oup.com/nar/article/41/6/e72/2902438
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http://dx.doi.org/10.1093/nar/gks1467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616706PMC
April 2013

Evidence of inbreeding depression on human height.

PLoS Genet 2012 19;8(7):e1002655. Epub 2012 Jul 19.

Centre for Population Health Sciences, University of Edinburgh, Edinburgh, Scotland, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1002655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400549PMC
January 2013

Assessing non-response to a mailed health survey including self-collection of biological material.

Eur J Public Health 2011 Aug 10;21(4):538-42. Epub 2010 May 10.

Department of Public Health, University of Tartu, Tartu, Estonia.

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https://academic.oup.com/eurpub/article-lookup/doi/10.1093/e
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http://dx.doi.org/10.1093/eurpub/ckq053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139099PMC
August 2011

Bladder dysfunction in hereditary spastic paraplegia: what to expect?

J Neurol Neurosurg Psychiatry 2010 Mar 2;81(3):263-6. Epub 2009 Sep 2.

Department of Neurology, University of Tartu, Puusepa 2, Tartu 51014, Estonia.

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http://dx.doi.org/10.1136/jnnp.2009.180331DOI Listing
March 2010

Population-based type-specific prevalence of high-risk human papillomavirus infection in Estonia.

BMC Infect Dis 2010 Mar 11;10:63. Epub 2010 Mar 11.

Department of Public Health, University of Tartu, Tartu, Estonia.

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http://dx.doi.org/10.1186/1471-2334-10-63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841185PMC
March 2010

Inflammation and oxidative stress are associated differently with endothelial function and arterial stiffness in healthy subjects and in patients with atherosclerosis.

Scand J Clin Lab Invest 2008 ;68(7):594-601

Department of Biochemistry, National and European Center of Excellence of Molecular and Clinical Medicine, University of Tartu, Tartu, Estonia.

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http://dx.doi.org/10.1080/00365510801930626DOI Listing
May 2009

Impact of oxidative stress on arterial elasticity in patients with atherosclerosis.

Am J Hypertens 2006 Sep;19(9):902-8

Department of Biochemistry, Center of Molecular and Clinical Medicine, University of Tartu, Tartu, Estonia.

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http://dx.doi.org/10.1016/j.amjhyper.2006.02.003DOI Listing
September 2006

Effects of stimulation of nitric oxide synthesis on large artery stiffness in patients with peripheral arterial disease.

Atherosclerosis 2006 Apr 26;185(2):368-74. Epub 2005 Jul 26.

Department of Biochemistry, Centre of Molecular and Clinical Medicine, University of Tartu, 19 Ravila Street, Tartu 50411, Estonia.

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http://linkinghub.elsevier.com/retrieve/pii/S002191500500389
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http://dx.doi.org/10.1016/j.atherosclerosis.2005.06.014DOI Listing
April 2006