Marshall B Elam

Marshall B Elam

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Marshall B Elam

Marshall B Elam

Publications by authors named "Marshall B Elam"

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Insulin-induced de novo lipid synthesis occurs mainly via mTOR-dependent regulation of proteostasis of SREBP-1c.

Mol Cell Biochem 2019 Sep 20. Epub 2019 Sep 20.

Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN, 38163, USA.

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http://dx.doi.org/10.1007/s11010-019-03625-5DOI Listing
September 2019

Phosphorylation dependent proteostasis of sterol regulatory element binding proteins.

Biochim Biophys Acta Mol Cell Biol Lipids 2019 Aug 5;1864(8):1145-1156. Epub 2019 May 5.

Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, United States; Department of Veterans Affairs Medical Center, Memphis, TN 38104, United States.

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http://dx.doi.org/10.1016/j.bbalip.2019.04.015DOI Listing
August 2019

Sex-specific differences in hepatic steatosis in obese spontaneously hypertensive (SHROB) rats.

Biol Sex Differ 2018 09 10;9(1):40. Epub 2018 Sep 10.

Department of Veterans Affairs Medical Center, 1030 Jefferson Avenue, Memphis, TN, 38104, USA.

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http://dx.doi.org/10.1186/s13293-018-0202-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131947PMC
September 2018

Secretory phospholipase A group IIA modulates insulin sensitivity and metabolism.

J Lipid Res 2017 09 29;58(9):1822-1833. Epub 2017 Jun 29.

Departments of Pharmacology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN

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http://dx.doi.org/10.1194/jlr.M076141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580896PMC
September 2017

Docosahexaenoic acid inhibits proteolytic processing of sterol regulatory element-binding protein-1c (SREBP-1c) via activation of AMP-activated kinase.

Biochim Biophys Acta 2015 Dec 29;1851(12):1521-9. Epub 2015 Aug 29.

Department of Veterans Affairs Medical Center, 1030 Jefferson Avenue, Memphis TN 38104, United States; Department of Pharmacology, 874 Union Avenue, Memphis, TN 38163, United States.

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http://dx.doi.org/10.1016/j.bbalip.2015.08.007DOI Listing
December 2015

Glycogen synthase kinase-3-mediated phosphorylation of serine 73 targets sterol response element binding protein-1c (SREBP-1c) for proteasomal degradation.

Biosci Rep 2015 Nov 20;36(1):e00284. Epub 2015 Nov 20.

Department of Veterans Affairs Medical Center, 1030 Jefferson Avenue, Memphis, TN 38104, U.S.A. Department of Pharmacology, College of Medicine, the University of Tennessee Health Science Center, 874 Union Avenue, Memphis, TN 38163, U.S.A.

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http://dx.doi.org/10.1042/BSR20150234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718510PMC
November 2015

A streamlined protocol for extracting RNA and genomic DNA from archived human blood and muscle.

Anal Biochem 2015 Apr 9;474:25-7. Epub 2015 Jan 9.

Department of Veterans Affairs Medical Center, Memphis, TN 38104, USA; Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38163, USA.

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http://dx.doi.org/10.1016/j.ab.2014.12.021DOI Listing
April 2015

Phosphorylation of sterol regulatory element binding protein-1a by protein kinase A (PKA) regulates transcriptional activity.

Biochem Biophys Res Commun 2014 Jul 20;449(4):449-54. Epub 2014 May 20.

Department of Pharmacology, University of Tennessee Health Science Center, Memphis, TN, USA; Research Service, Veteran's Affairs Medical Center, Memphis, TN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.05.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670028PMC
July 2014

Nuclear corepressors mediate the repression of phospholipase A2 group IIa gene transcription by thyroid hormone.

J Biol Chem 2013 Jun 29;288(23):16321-33. Epub 2013 Apr 29.

Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.

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http://dx.doi.org/10.1074/jbc.M112.445569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675570PMC
June 2013

Role of sirtuin 1 in the regulation of hepatic gene expression by thyroid hormone.

J Biol Chem 2013 Jan 3;288(2):807-18. Epub 2012 Dec 3.

Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.

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http://dx.doi.org/10.1074/jbc.M112.437970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543030PMC
January 2013

Clinical and laboratory phenotype of patients experiencing statin intolerance attributable to myalgia.

J Clin Lipidol 2011 Jul-Aug;5(4):299-307. Epub 2011 Jun 12.

Department of Medicine, Veterans Affairs Medical Center, Memphis, TN, USA.

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http://dx.doi.org/10.1016/j.jacl.2011.05.005DOI Listing
November 2011

Regulation of pyruvate dehydrogenase kinase 4 (PDK4) by CCAAT/enhancer-binding protein beta (C/EBPbeta).

J Biol Chem 2011 Jul 17;286(27):23799-807. Epub 2011 May 17.

Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.

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http://dx.doi.org/10.1074/jbc.M111.246389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129161PMC
July 2011

Regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) gene expression by glucocorticoids and insulin.

Mol Cell Endocrinol 2010 Feb 22;315(1-2):159-67. Epub 2009 Aug 22.

Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center, 874 Union Avenue, Memphis, TN 38163, USA.

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http://dx.doi.org/10.1016/j.mce.2009.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815206PMC
February 2010

Regulation of pyruvate dehydrogenase kinase 4 (PDK4) by thyroid hormone: role of the peroxisome proliferator-activated receptor gamma coactivator (PGC-1 alpha).

J Biol Chem 2010 Jan 30;285(4):2375-85. Epub 2009 Nov 30.

Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.

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http://dx.doi.org/10.1074/jbc.M109.039081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2807296PMC
January 2010

N-3 polyunsaturated fatty acids suppress insulin-induced SREBP-1c transcription via reduced trans-activating capacity of LXRalpha.

Biochim Biophys Acta 2009 Dec 27;1791(12):1190-6. Epub 2009 Aug 27.

Department of Pharmacology, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA.

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http://dx.doi.org/10.1016/j.bbalip.2009.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783506PMC
December 2009

SREBPs: the crossroads of physiological and pathological lipid homeostasis.

Trends Endocrinol Metab 2008 Mar;19(2):65-73

Department of Pharmacology, University of Tennessee Health Science Center, 874 Union Avenue, Memphis, TN 38163, USA.

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http://dx.doi.org/10.1016/j.tem.2007.10.009DOI Listing
March 2008

Expression of the rat sterol regulatory element-binding protein-1c gene in response to insulin is mediated by increased transactivating capacity of specificity protein 1 (Sp1).

J Biol Chem 2007 Jun 20;282(24):17517-29. Epub 2007 Apr 20.

Medical and Research Service, Department of Veterans Affairs Medical Center, Memphis, Tennessee 38104, USA.

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http://dx.doi.org/10.1074/jbc.M702228200DOI Listing
June 2007

Evolution of the lipid trial protocol of the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial.

Am J Cardiol 2007 Jun 12;99(12A):56i-67i. Epub 2007 Apr 12.

Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, USA.

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http://dx.doi.org/10.1016/j.amjcard.2007.03.024DOI Listing
June 2007

Regulation of carnitine palmitoyltransferase I (CPT-Ialpha) gene expression by the peroxisome proliferator activated receptor gamma coactivator (PGC-1) isoforms.

Mol Cell Endocrinol 2007 Mar 16;267(1-2):6-16. Epub 2006 Dec 16.

Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center, 874 Union Avenue, Memphis, TN 38163, USA.

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http://dx.doi.org/10.1016/j.mce.2006.11.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892282PMC
March 2007

Effect of combination lipid-modifying therapy on the triglyceride lowering effect of fish oil.

Am J Med Sci 2007 Mar;333(3):168-72

Department of Medicine, VA Medical Center-Memphis, USA.

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http://dx.doi.org/10.1097/MAJ.0b013e3180312ebfDOI Listing
March 2007

Estrogen-related receptors stimulate pyruvate dehydrogenase kinase isoform 4 gene expression.

J Biol Chem 2006 Dec 1;281(52):39897-906. Epub 2006 Nov 1.

Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.

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http://dx.doi.org/10.1074/jbc.M608657200DOI Listing
December 2006

Cholesterol management: targeting a lower low-density lipoprotein cholesterol concentration increases adult treatment panel-III goal attainment.

Am J Cardiol 2006 Jun 19;97(11):1667-9. Epub 2006 Apr 19.

Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.

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http://dx.doi.org/10.1016/j.amjcard.2005.12.060DOI Listing
June 2006

Cloning of the rat pyruvate dehydrogenase kinase 4 gene promoter: activation of pyruvate dehydrogenase kinase 4 by the peroxisome proliferator-activated receptor gamma coactivator.

J Biol Chem 2005 Aug 20;280(33):29525-32. Epub 2005 Jun 20.

Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center, Memphis, 38163, USA.

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http://dx.doi.org/10.1074/jbc.M502236200DOI Listing
August 2005

Posttranslational processing of SREBP-1 in rat hepatocytes is regulated by insulin and cAMP.

Biochem Biophys Res Commun 2005 Jun;332(1):174-80

Department of Veterans Affairs Medical Center, Memphis, TN, USA.

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http://dx.doi.org/10.1016/j.bbrc.2005.04.112DOI Listing
June 2005

Peroxisomal proliferator-activated receptor-gamma coactivator-1 alpha (PGC-1 alpha) enhances the thyroid hormone induction of carnitine palmitoyltransferase I (CPT-I alpha).

J Biol Chem 2004 Dec 6;279(52):53963-71. Epub 2004 Oct 6.

Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA.

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http://dx.doi.org/10.1074/jbc.M406028200DOI Listing
December 2004

Peroxisomal proliferator activated receptor gamma coactivator (PGC-1alpha) stimulates carnitine palmitoyltransferase I (CPT-Ialpha) through the first intron.

Biochim Biophys Acta 2004 Aug;1679(2):164-73

Department of Pharmacology, College of Medicine, University of Tennessee Health Science Center, 874 Union Avenue, Memphis, TN 38163, USA.

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http://dx.doi.org/10.1016/j.bbaexp.2004.06.006DOI Listing
August 2004

Diabetes, plasma insulin, and cardiovascular disease: subgroup analysis from the Department of Veterans Affairs high-density lipoprotein intervention trial (VA-HIT).

Arch Intern Med 2002 Dec 9-23;162(22):2597-604

Section of General Internal Medicine (111O), Veterans Affairs Medical Center, 1 Veterans Dr, Minneapolis, MN 55417.

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http://dx.doi.org/10.1001/archinte.162.22.2597DOI Listing
January 2003

Clinical manifestation of atherosclerotic peripheral arterial disease and the role of cilostazol in treatment of intermittent claudication.

J Clin Pharmacol 2002 Dec;42(12):1291-8

Department of Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA.

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http://dx.doi.org/10.1177/0091270002042012002DOI Listing
December 2002

Regulation of the rat SREBP-1c promoter in primary rat hepatocytes.

Biochem Biophys Res Commun 2002 Jan;290(1):256-62

Department of Veterans Affairs Medical Center, Memphis, Tennessee, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0196148
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http://dx.doi.org/10.1006/bbrc.2001.6148DOI Listing
January 2002