Marsha Pellegrino

Manipulating the Metabolism to Improve the Efficacy of CAR T-Cell Immunotherapy.

Authors:

Marsha Pellegrino Francesca Del Bufalo Biagio De Angelis Concetta Quintarelli Ignazio Caruana Emmanuel de Billy

Cells 2020 Dec 24;10(1). Epub 2020 Dec 24.

Department of Onco-hematology, Cell and Gene Therapy, Bambino Gesù Children's Hospital-IRCCS, 00146 Rome, Italy.

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December 2020

Effect of p53 activation through targeting MDM2/MDM4 heterodimer on T regulatory and effector cells in the peripheral blood of Type 1 diabetes patients.

Authors:

Marsha Pellegrino Gianandrea Traversi Andrea Arena Marco Cappa M Manuela Rosado Marco Andreani Domenico V Delfino Fabiola Moretti Alessandra Fierabracci

PLoS One 2020 29;15(1):e0228296. Epub 2020 Jan 29.

Infectivology and Clinical Trials Research Department, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

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April 2020

Estrogens Counteract Platinum-Chemosensitivity by Modifying the Subcellular Localization of MDM4.

Authors:

Rossella Lucà Giorgia di Blasio Daniela Gallo Valentina Monteleone Isabella Manni Laura Fici Marianna Buttarelli Germana Ciolli Marsha Pellegrino Emanuela Teveroni Silvia Maiullari Alessandra Ciucci Alessandro Apollo Francesca Mancini Maria Pia Gentileschi Gian Franco Zannoni Alfredo Pontecorvi Giovanni Scambia Fabiola Moretti

Cancers (Basel) 2019 Sep 12;11(9). Epub 2019 Sep 12.

Institute Cell Biology and Neurobiology, National Research Council of Italy (CNR), 00015 Monterotondo, Italy.

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September 2019

Identification and functional characterization of CD8+ T regulatory cells in type 1 diabetes patients.

Authors:

Marsha Pellegrino Antonino Crinò Manuela M Rosado Alessandra Fierabracci

PLoS One 2019 16;14(1):e0210839. Epub 2019 Jan 16.

Infectivology and Clinical Trials Research Division, Bambino Gesù Children's Hospital, Rome, Italy.

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October 2019

Exploiting novel tailored immunotherapies of type 1 diabetes: Short interfering RNA delivered by cationic liposomes enables efficient down-regulation of variant PTPN22 gene in T lymphocytes.

Authors:

Marsha Pellegrino Francesca Ceccacci Stefania Petrini Anita Scipioni Serena De Santis Marco Cappa Giovanna Mancini Alessandra Fierabracci

Nanomedicine 2019 06 12;18:371-379. Epub 2018 Nov 12.

Infectivology and Clinical Trials Research Area. Electronic address:

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June 2019

A Novel Homozygous Mutation of the Gene in an APECED Patient From Pakistan: Case Report and Review of the Literature.

Authors:

Marsha Pellegrino Emanuele Bellacchio Rudina Dhamo Federica Frasca Corrado Betterle Alessandra Fierabracci

Front Immunol 2018 13;9:1835. Epub 2018 Aug 13.

Infectivology and Clinical Trials Research Division, Bambino Gesù Children's Hospital, Rome, Italy.

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September 2019

APECED in Turkey: A case report and insights on genetic and phenotypic variability.

Authors:

Alessandra Fierabracci Marsha Pellegrino Federica Frasca Sara Sebnem Kilic Corrado Betterle

Clin Immunol 2018 09 3;194:60-66. Epub 2018 Jul 3.

Endocrine Unit, Department of Medicine (DIMED), University of Padua, Via Ospedale Civile 105, 35128 Padua, Italy. Electronic address:

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September 2018

Identification of GAD65 AA 114-122 reactive 'memory-like' NK cells in newly diagnosed Type 1 diabetic patients by HLA-class I pentamers.

Authors:

Valentina Perri Elena Gianchecchi Loredana Cifaldi Marsha Pellegrino Ezio Giorda Marco Andreani Marco Cappa Alessandra Fierabracci

PLoS One 2017 13;12(12):e0189615. Epub 2017 Dec 13.

Type 1 Diabetes Centre, Infectivology and Clinical Trials Research Department, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.

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January 2018

Use of short interfering RNA delivered by cationic liposomes to enable efficient down-regulation of PTPN22 gene in human T lymphocytes.

Authors:

Valentina Perri Marsha Pellegrino Francesca Ceccacci Anita Scipioni Stefania Petrini Elena Gianchecchi Anna Lo Russo Serena De Santis Giovanna Mancini Alessandra Fierabracci

PLoS One 2017 24;12(4):e0175784. Epub 2017 Apr 24.

Type 1 Diabetes Centre, Infectivology and Clinical Trials Area, Children's Hospital Bambino Gesù, Rome, Italy.

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September 2017

MDM4 actively restrains cytoplasmic mTORC1 by sensing nutrient availability.

Authors:

Francesca Mancini Emanuela Teveroni Giusy Di Conza Valentina Monteleone Ivan Arisi Marsha Pellegrino Marianna Buttarelli Luisa Pieroni Mara D'Onofrio Andrea Urbani Alfredo Pontecorvi Massimiliano Mazzone Fabiola Moretti

Mol Cancer 2017 03 7;16(1):55. Epub 2017 Mar 7.

Institute of Cell Biology and Neurobiology, National Research Council of Italy (CNR), 00143, Rome, Italy.

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March 2017

Estrogens enhance myoblast differentiation in facioscapulohumeral muscular dystrophy by antagonizing DUX4 activity.

Authors:

Emanuela Teveroni Marsha Pellegrino Sabrina Sacconi Patrizia Calandra Isabella Cascino Stefano Farioli-Vecchioli Angela Puma Matteo Garibaldi Roberta Morosetti Giorgio Tasca Enzo Ricci Carlo Pietro Trevisan Giuliana Galluzzi Alfredo Pontecorvi Marco Crescenzi Giancarlo Deidda Fabiola Moretti

J Clin Invest 2017 Apr 6;127(4):1531-1545. Epub 2017 Mar 6.

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April 2017

Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents.

Authors:

Nadia Canu Ilaria Pagano Luca Rosario La Rosa Marsha Pellegrino Maria Teresa Ciotti Delio Mercanti Fabiola Moretti Valentina Sposato Viviana Triaca Carla Petrella Ichiro N Maruyama Andrea Levi Pietro Calissano

Front Mol Neurosci 2017 31;10:15. Epub 2017 Jan 31.

European Brain Research InstituteRome, Italy; Institute of Cellular Biology and Neurobiology, National Council of Research of RomeRome, Italy.

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January 2017

The Double Role of p53 in Cancer and Autoimmunity and Its Potential as Therapeutic Target.

Authors:

Alessandra Fierabracci Marsha Pellegrino

Int J Mol Sci 2016 Nov 25;17(12). Epub 2016 Nov 25.

Infectivology and Clinical Trials Area, Children's Hospital Bambino Gesù, 00146 Rome, Italy.

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November 2016

Peptides and peptidomimetics in the p53/MDM2/MDM4 circuitry - a patent review.

Authors:

Emanuela Teveroni Rossella Lucà Marsha Pellegrino Germana Ciolli Alfredo Pontecorvi Fabiola Moretti

Expert Opin Ther Pat 2016 Dec 20;26(12):1417-1429. Epub 2016 Sep 20.

a Institute of Cell Biology and Neurobiology , CNR , Roma , Italy.

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December 2016

Targeting the MDM2/MDM4 interaction interface as a promising approach for p53 reactivation therapy.

Cancer Res 2015 Nov 10;75(21):4560-72. Epub 2015 Sep 10.

Institute of Cell Biology and Neurobiology, CNR, Roma, Italy.

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November 2015

IGF-1R/MDM2 relationship confers enhanced sensitivity to RITA in Ewing sarcoma cells.

Authors:

Giusy Di Conza Marianna Buttarelli Olimpia Monti Marsha Pellegrino Francesca Mancini Alfredo Pontecorvi Katia Scotlandi Fabiola Moretti

Mol Cancer Ther 2012 Jun 28;11(6):1247-56. Epub 2012 Mar 28.

Cell Biology and Neurobiology Institute-CNR/Fondazione Santa Lucia, Rome, Italy.

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June 2012

MDM4 (MDMX) localizes at the mitochondria and facilitates the p53-mediated intrinsic-apoptotic pathway.

Authors:

Francesca Mancini Giusy Di Conza Marsha Pellegrino Cinzia Rinaldo Andrea Prodosmo Simona Giglio Igea D'Agnano Fulvio Florenzano Lara Felicioni Fiamma Buttitta Antonio Marchetti Ada Sacchi Alfredo Pontecorvi Silvia Soddu Fabiola Moretti

EMBO J 2009 Jul 11;28(13):1926-39. Epub 2009 Jun 11.

Institute of Neurobiology and Molecular Medicine, National Council of Research, Rome, Italy.

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July 2009

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