Publications by authors named "Markus Weiler"

58Publications

Optimized Trientine-Dihydrochloride Therapy in Pediatric Patients with Wilson Disease: Is Weight-Based Dosing Justified?

J Pediatr Gastroenterol Nutr 2020 Aug 14. Epub 2020 Aug 14.

Department of Gastroenterology and Hepatology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1097/MPG.0000000000002902DOI Listing
August 2020

Xylem sap phosphorus sampling using microdialysis-a non-destructive high sampling frequency method tested under laboratory and field conditions.

Tree Physiol 2020 Jun 26. Epub 2020 Jun 26.

Chair of Hydrology, Faculty of Environment and Natural Resources, University of Freiburg, Germany.

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http://dx.doi.org/10.1093/treephys/tpaa081DOI Listing
June 2020

Out of balance - Postural control in cancer patients before and after neurotoxic chemotherapy.

Gait Posture 2020 03 15;77:156-163. Epub 2020 Jan 15.

Working Group Exercise Oncology, Division of Medical Oncology, National Center for Tumor Diseases (NCT) and Heidelberg University Hospital, Im Neuenheimer Feld 460, 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.gaitpost.2020.01.012DOI Listing
March 2020

[Spinal Muscular Atrophy - expert recommendations for the use of nusinersen in adult patients].

Fortschr Neurol Psychiatr 2019 Dec 17;87(12):703-710. Epub 2019 Dec 17.

Klinik für Neurologie, Universitätsmedizin Essen.

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http://dx.doi.org/10.1055/a-0996-0994DOI Listing
December 2019

Quantitative MR neurography biomarkers in 5q-linked spinal muscular atrophy.

Neurology 2019 08 10;93(7):e653-e664. Epub 2019 Jul 10.

From the Department of Neuroradiology (J.K., T.H., A.P., M.J., S.H., M.B.), Division of Child Neurology and Metabolic Medicine (A.Z., A.S.), Center for Child and Adolescent Medicine, Department of Neurology (G.S., W.W., M.W.), and Department of Neuroradiology (S.H.), Division of Experimental Radiology, Heidelberg University Hospital, Germany; Department of Neurology (J.M.H.), University of Michigan, Ann Arbor; Medical Faculty (M.J.), University of Tübingen; and German Cancer Consortium (DKTK) within the German Cancer Research Center (DKFZ) (W.W.), Heidelberg, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000007945DOI Listing
August 2019

[Gene therapies for neuromuscular diseases].

Nervenarzt 2019 Aug;90(8):809-816

Zentrum für Kinder- und Jugendmedizin, Sektion für Neuropädiatrie und Stoffwechselmedizin, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 430, 69120, Heidelberg, Deutschland.

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http://dx.doi.org/10.1007/s00115-019-0761-zDOI Listing
August 2019

Long-term evaluation of urinary copper excretion and non-caeruloplasmin associated copper in Wilson disease patients under medical treatment.

J Inherit Metab Dis 2019 03 11;42(2):371-380. Epub 2019 Feb 11.

Department of Gastroenterology and Hepatology, University Hospital Heidelberg, INF 410, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1002/jimd.12046DOI Listing
March 2019

Novel challenges in spinal muscular atrophy - How to screen and whom to treat?

Ann Clin Transl Neurol 2019 01 13;6(1):197-205. Epub 2018 Nov 13.

Division of Child Neurology and Metabolic Medicine Center for Child and Adolescent Medicine University Hospital Heidelberg Heidelberg Germany.

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http://doi.wiley.com/10.1002/acn3.689
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http://dx.doi.org/10.1002/acn3.689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331314PMC
January 2019

MR neurography biomarkers to characterize peripheral neuropathy in AL amyloidosis.

Neurology 2018 08 20;91(7):e625-e634. Epub 2018 Jul 20.

From the Department of Neuroradiology (J.K., S.H., T.H., M.P., M.B.), Amyloidosis Center Heidelberg (J.K., M.W., J.P., S.O.S., E.H., C.K., U.H.), Department of Neurology (M.W., J.P., E.H.), Division of Experimental Radiology, Department of Neuroradiology (S.H.), and Medical Department V (S.O.S., C.K., U.H.), Heidelberg University Hospital, Germany; Department of Neurology (J.M.H.), University of Michigan, Ann Arbor; and Department of Neuroradiology (M.P.), Würzburg University Hospital, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000006002DOI Listing
August 2018

Employing stable isotopes to determine the residence times of soil water and the temporal origin of water taken up by Fagus sylvatica and Picea abies in a temperate forest.

New Phytol 2018 09 11;219(4):1300-1313. Epub 2018 Jun 11.

Department of Environmental Sciences - Botany, University Basel, Schönbeinstrasse 6, Basel, 4056, Switzerland.

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http://dx.doi.org/10.1111/nph.15255DOI Listing
September 2018

A sprinkling experiment to quantify celerity-velocity differences at the hillslope scale.

Hydrol Earth Syst Sci 2017 27;21(11):5891-5910. Epub 2017 Nov 27.

Chair of Hydrology, Faculty of Environment and Natural Resources, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.5194/hess-21-5891-2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739528PMC
November 2017

Comparative assessment of clinical rating scales in Wilson's disease.

BMC Neurol 2017 Jul 21;17(1):140. Epub 2017 Jul 21.

Department of Neurology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1186/s12883-017-0921-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521125PMC
July 2017

Sural nerve injury in familial amyloid polyneuropathy: MR neurography vs clinicopathologic tools.

Neurology 2017 Aug 5;89(5):475-484. Epub 2017 Jul 5.

From the Department of Neuroradiology (J.K., S.H., M.P., M.B.), Amyloidosis Center Heidelberg (J.K., U.H., J.C.P., C.K., S.O.S., E.H., A.V.K., M.W.), Department of Neuropathology (F.S.), Medical Department V (U.H., C.K., S.O.S.), Department of Neurology (J.C.P., E.H., M.W.), Division of Experimental Radiology (S.H.), Department of Neuroradiology, and Medical Department III (A.V.K.), Heidelberg University Hospital; CCU Neuropathology (F.S.), German Consortium for Translational Cancer Research, German Cancer Research Center, Heidelberg, Germany; Department of Neurology (J.M.H.), University of Michigan, Ann Arbor; Department of Pathology (C.R.), University of Kiel; and Department of Neuroradiology (M.P.), Würzburg University Hospital, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000004178DOI Listing
August 2017

Posterior interosseous neuropathy: Supinator syndrome vs fascicular radial neuropathy.

Neurology 2016 Nov 28;87(18):1884-1891. Epub 2016 Sep 28.

From the Departments of Neuroradiology (P.B., A.X., D.S., M.B., M.P.) and Neurology (M.W.), Heidelberg University Hospital; Department of Radiology (P.B.), German Cancer Research Center, Heidelberg; and Center for Peripheral Neurology (H.K.), Hamburg, Germany; and the Department of Neuroradiology, University Clinic Würzburg.

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http://dx.doi.org/10.1212/WNL.0000000000003287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100717PMC
November 2016

Bottom-Up Fabrication of Hybrid Plasmonic Sensors: Gold-Capped Hydrogel Microspheres Embedded in Periodic Metal Hole Arrays.

ACS Appl Mater Interfaces 2016 Oct 26;8(39):26392-26399. Epub 2016 Sep 26.

Department of New Materials and Biosystems, Max Planck Institute for Intelligent Systems , Heisenbergstr. 3, 70569 Stuttgart, Germany.

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http://dx.doi.org/10.1021/acsami.6b08636DOI Listing
October 2016

Recovery of trees from drought depends on belowground sink control.

Nat Plants 2016 07 18;2:16111. Epub 2016 Jul 18.

Swiss Federal Institute for Forest, Snow and Landscape Research (WSL), Zürcherstrasse 111, 8903 Birmensdorf, Switzerland.

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http://dx.doi.org/10.1038/nplants.2016.111DOI Listing
July 2016

Correcting Laser-Based Water Stable Isotope Readings Biased by Carrier Gas Changes.

Environ Sci Technol 2016 07 22;50(13):7074-81. Epub 2016 Jun 22.

Institute of Groundwater Ecology, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH) , Ingolstaedter Landstrasse 1, 85764 Neuherberg, Germany.

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http://dx.doi.org/10.1021/acs.est.6b01124DOI Listing
July 2016

A method for in situ monitoring of the isotope composition of tree xylem water using laser spectroscopy.

Plant Cell Environ 2016 09 3;39(9):2055-63. Epub 2016 Jun 3.

Chair of Hydrology, Faculty of Environment and Natural Resources, University of Freiburg, Fahnenbergplatz, 79098, Freiburg, Germany.

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http://dx.doi.org/10.1111/pce.12725DOI Listing
September 2016

High-resolution isotope measurements resolve rapid ecohydrological dynamics at the soil-plant interface.

New Phytol 2016 May 10;210(3):839-49. Epub 2016 Feb 10.

Chair of Hydrology, Faculty of Environment and Natural Resources, University of Freiburg, Fahnenbergplatz, Freiburg, 79098, Germany.

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http://dx.doi.org/10.1111/nph.13868DOI Listing
May 2016

NDRG1 overexpressing gliomas are characterized by reduced tumor vascularization and resistance to antiangiogenic treatment.

Cancer Lett 2016 10 20;380(2):568-76. Epub 2015 Aug 20.

Department of Neurosurgery, Neurochirurgische Klinik - Universitätsmedizin Charite, Augustenburger Platz 1, 13353 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2015.06.026DOI Listing
October 2016

Somatotopic fascicular organization of the human sciatic nerve demonstrated by MR neurography.

Neurology 2015 Apr 3;84(17):1782-7. Epub 2015 Apr 3.

From the Departments of Neuroradiology (P.B., M.B., M.P.) and Neurology (M.W.), Heidelberg University Hospital, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000001526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4424125PMC
April 2015

Diagnostic signs of motor neuropathy in MR neurography: nerve lesions and muscle denervation.

Eur Radiol 2015 May 30;25(5):1497-503. Epub 2014 Nov 30.

Department of Neuroradiology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00330-014-3498-xDOI Listing
May 2015

Bottom-up fabrication of nanohole arrays loaded with gold nanoparticles: extraordinary plasmonic sensors.

Chem Commun (Camb) 2014 Dec 28;50(97):15419-22. Epub 2014 Oct 28.

Max Planck Institute for Intelligent Systems, Department of New Materials and Biosystems, Heisenbergstr. 3, 70569 Stuttgart, Germany.

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http://dx.doi.org/10.1039/c4cc05208kDOI Listing
December 2014

Optical characterization of porous silicon monolayers decorated with hydrogel microspheres.

Nanoscale Res Lett 2014 22;9(1):425. Epub 2014 Aug 22.

Department of New Materials and Biosystems, Max Planck Institute for Intelligent Systems, Heisenbergstr. 3, Stuttgart 70569, Germany.

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http://dx.doi.org/10.1186/1556-276X-9-425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151277PMC
September 2014

MGMT testing--the challenges for biomarker-based glioma treatment.

Nat Rev Neurol 2014 Jul 10;10(7):372-85. Epub 2014 Jun 10.

Department of Neuropathology, Heinrich Heine University, Germany.

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http://dx.doi.org/10.1038/nrneurol.2014.100DOI Listing
July 2014

Peripheral neuropathy: detection with diffusion-tensor imaging.

Radiology 2014 Oct 17;273(1):185-93. Epub 2014 May 17.

From the Department of Neuroradiology (P.B., M.P., M.R., A.H., A.R., M.B.), Section of Experimental Neuroradiology, Department of Neuroradiology (S.H.), and Department of Neurology (M.W.), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; and Clinical Cooperation Unit Neurooncology, German Cancer Research Center, Heidelberg, Germany (M.W.).

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http://dx.doi.org/10.1148/radiol.14132837DOI Listing
October 2014

Targeting self-renewal in high-grade brain tumors leads to loss of brain tumor stem cells and prolonged survival.

Cell Stem Cell 2014 Aug 15;15(2):185-98. Epub 2014 May 15.

Helmholtz Young Investigator Group, Normal and Neoplastic CNS Stem Cells, DKFZ-ZMBH Alliance, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19345909140014
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http://dx.doi.org/10.1016/j.stem.2014.04.007DOI Listing
August 2014

Anterior interosseous nerve syndrome: fascicular motor lesions of median nerve trunk.

Neurology 2014 Feb 10;82(7):598-606. Epub 2014 Jan 10.

From the Departments of Neuroradiology (M.P., P.B., M.B.) and Neurology (H.-M.M., M.W.), Heidelberg University Hospital; Clinical Cooperation Unit Neurooncology (M.W.), German Cancer Research Center (DKFZ), Heidelberg; Department of Neurology (J.S.), RWTH University Hospital Aachen; and Center for Neurology and Clinical Neurophysiology Neuer Wall (H.K.), Hamburg, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000000128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963415PMC
February 2014

mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy.

Proc Natl Acad Sci U S A 2014 Jan 23;111(1):409-14. Epub 2013 Dec 23.

German Cancer Consortium, Clinical Cooperation Units Neurooncology and Neuropathology, Helmholtz Group Experimental Neuroimmunology, Small Animal Imaging Facility, Biostatistics, and Functional Proteome Analysis, German Cancer Research Center, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1073/pnas.1314469111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890826PMC
January 2014

Prognostic or predictive value of MGMT promoter methylation in gliomas depends on IDH1 mutation.

Neurology 2013 Oct 25;81(17):1515-22. Epub 2013 Sep 25.

From the Departments of Neuro-oncology (W.W., M.P., A.S., B.W., M. Weiler) and Neuropathology (A.v.D.), University of Heidelberg; German Cancer Consortium (DKTK) (W.W., B.W., M. Weiler), Clinical Cooperation Unit Neuro-oncology and Clinical Cooperation Unit Neuropathology (A.v.D.), German Cancer Research Center, Heidelberg; Department of Medical Biometry (C.M.), University of Tübingen; Institute for Medical Informatics, Statistics and Epidemiology (B.H., M.L.), University Leipzig; Departments of Neurosurgery (M.C.S.) and Neuropathology (G.R.), Heinrich-Heine-University and DKTK (G.R.), Düsseldorf; Department of Neurology (S.K.), University of Essen Medical School; Department of Neurosurgery (R.K.), Saarland University, Homburg, Germany; Department of Neurology (G.T., D.G., M. Weller), University Hospital Zurich, Switzerland; Department of Neurosurgery (M. Westphal), University Clinic Hamburg Eppendorf, Hamburg; Department of Neurosurgery (G.S.) and DKTK (G.S.), Technical University Dresden; and Department of Neurosurgery (M.S.), University of Bonn, Germany.

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http://dx.doi.org/10.1212/WNL.0b013e3182a95680DOI Listing
October 2013

Differentiation of glioblastoma and primary CNS lymphomas using susceptibility weighted imaging.

Eur J Radiol 2013 Mar 10;82(3):552-6. Epub 2012 Dec 10.

Department of Neuroradiology, University of Heidelberg Medical Center, INF 400, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ejrad.2012.11.002DOI Listing
March 2013

Molecular predictors of outcome in low-grade glioma.

Curr Opin Neurol 2012 Dec;25(6):767-73

Department of Neurooncology, Neurology Clinic and National Center for Tumor Diseases, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1097/WCO.0b013e32835a0217DOI Listing
December 2012

mTORC 2:1 for chemotherapy sensitization in glioblastoma.

Cancer Discov 2011 Nov;1(6):475-6

Clinical Cooperation Unit Neurooncology, German Cancer Research Center, Department of Neurooncology at the National Center for Tumor Diseases, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1158/2159-8290.CD-11-0264DOI Listing
November 2011

Gadofluorine M enhanced MRI in experimental glioma: superior and persistent intracellular tumor enhancement compared with conventional MRI.

J Magn Reson Imaging 2012 Mar 1;35(3):551-60. Epub 2011 Nov 1.

Department of Neuroradiology, University of Heidelberg, Im Neuenheimer Feld 400, Heidelberg, Germany.

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http://doi.wiley.com/10.1002/jmri.22869
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http://dx.doi.org/10.1002/jmri.22869DOI Listing
March 2012

Pathway inhibition: emerging molecular targets for treating glioblastoma.

Neuro Oncol 2011 Jun;13(6):566-79

Department of Neurooncology, National Center of Tumor Disease, University Clinic Heidelberg, Im Neuenheimer Feld 400, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1093/neuonc/nor039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107100PMC
June 2011

Patterns of progression in malignant glioma following anti-VEGF therapy: perceptions and evidence.

Curr Neurol Neurosci Rep 2011 Jun;11(3):305-12

Department of Neurooncology, University Clinic Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s11910-011-0184-0DOI Listing
June 2011

Defective p53 antiangiogenic signaling in glioblastoma.

Neuro Oncol 2010 Sep 26;12(9):894-907. Epub 2010 May 26.

Department of Neurology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1093/neuonc/noq051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940700PMC
September 2010

Chemoradiotherapy of newly diagnosed glioblastoma with intensified temozolomide.

Int J Radiat Oncol Biol Phys 2010 Jul 14;77(3):670-6. Epub 2009 Oct 14.

Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1016/j.ijrobp.2009.05.031DOI Listing
July 2010

Enzastaurin-induced apoptosis in glioma cells is caspase-dependent and inhibited by BCL-XL.

J Neurochem 2008 Sep 24;106(6):2436-48. Epub 2008 Jul 24.

Laboratory of Molecular Neuro-Oncology, Department of General Neurology, University of Tübingen, Tübingen, Germany.

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http://doi.wiley.com/10.1111/j.1471-4159.2008.05586.x
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http://dx.doi.org/10.1111/j.1471-4159.2008.05586.xDOI Listing
September 2008

Migratory neural stem cells for improved thymidine kinase-based gene therapy of malignant gliomas.

Biochem Biophys Res Commun 2005 Mar;328(1):125-9

Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen, Hoppe-Seyler-Str. 3, D-72076 Tübingen, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2004.12.164DOI Listing
March 2005

RNA interference targeting transforming growth factor-beta enhances NKG2D-mediated antiglioma immune response, inhibits glioma cell migration and invasiveness, and abrogates tumorigenicity in vivo.

Cancer Res 2004 Oct;64(20):7596-603

Department of General Neurology, Hertie Institute for Clinical Brain Research and Institute for Cell Biology, Department of Immunology, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-1627DOI Listing
October 2004