Markus Scholz

Markus Scholz

UNVERIFIED PROFILE

Are you Markus Scholz?   Register this Author

Register author
Markus Scholz

Markus Scholz

Publications by authors named "Markus Scholz"

Are you Markus Scholz?   Register this Author

100Publications

3241Reads

37Profile Views

Genetically programmed changes in transcription of the novel progranulin regulator.

J Mol Med (Berl) 2020 Aug 3;98(8):1139-1148. Epub 2020 Jul 3.

Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, 04103, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00109-020-01942-7DOI Listing
August 2020

Cohort profile: The Leipzig Research Center for Civilization Diseases-Heart study (LIFE-Heart).

Int J Epidemiol 2020 Aug 3. Epub 2020 Aug 3.

Leipzig Research Center for Civilization Diseases (LIFE), University of Leipzig, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ije/dyaa075DOI Listing
August 2020

Adipocytokines are not associated with gestational diabetes mellitus but with pregnancy status.

Cytokine 2020 Jul 10;131:155088. Epub 2020 Apr 10.

University of Leipzig Medical Center, Medical Department III - Endocrinology, Nephrology, Rheumatology, 04103 Leipzig, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cyto.2020.155088DOI Listing
July 2020

Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood.

Authors:
Yan Zheng Tao Huang Tiange Wang Zhendong Mei Zhonghan Sun Tao Zhang Christina Ellervik Jin-Fang Chai Xueling Sim Rob M van Dam E-Shyong Tai Woon-Puay Koh Rajkumar Dorajoo Seang-Mei Saw Charumathi Sabanayagam Tien Yin Wong Preeti Gupta Peter Rossing Tarunveer S Ahluwalia Rebecca K Vinding Hans Bisgaard Klaus Bønnelykke Yujie Wang Mariaelisa Graff Trudy Voortman Frank J A van Rooij Albert Hofman Diana van Heemst Raymond Noordam Angela C Estampador Tibor V Varga Cornelia Enzenbach Markus Scholz Joachim Thiery Ralph Burkhardt Marju Orho-Melander Christina-Alexandra Schulz Ulrika Ericson Emily Sonestedt Michiaki Kubo Masato Akiyama Ang Zhou Tuomas O Kilpeläinen Torben Hansen Marcus E Kleber Graciela Delgado Mark McCarthy Rozenn N Lemaitre Janine F Felix Vincent W V Jaddoe Ying Wu Karen L Mohlke Terho Lehtimäki Carol A Wang Craig E Pennell Heribert Schunkert Thorsten Kessler Lingyao Zeng Christina Willenborg Annette Peters Wolfgang Lieb Veit Grote Peter Rzehak Berthold Koletzko Jeanette Erdmann Matthias Munz Tangchun Wu Meian He Caizheng Yu Cécile Lecoeur Philippe Froguel Dolores Corella Luis A Moreno Chao-Qiang Lai Niina Pitkänen Colin A Boreham Paul M Ridker Frits R Rosendaal Renée de Mutsert Chris Power Lavinia Paternoster Thorkild I A Sørensen Anne Tjønneland Kim Overvad Luc Djousse Fernando Rivadeneira Nanette R Lee Olli T Raitakari Mika Kähönen Jorma Viikari Jean-Paul Langhendries Joaquin Escribano Elvira Verduci George Dedoussis Inke König Beverley Balkau Oscar Coltell Jean Dallongeville Aline Meirhaeghe Philippe Amouyel Frédéric Gottrand Katja Pahkala Harri Niinikoski Elina Hyppönen Winfried März David A Mackey Dariusz Gruszfeld Katherine L Tucker Frédéric Fumeron Ramon Estruch Jose M Ordovas Donna K Arnett Dennis O Mook-Kanamori Dariush Mozaffarian Bruce M Psaty Kari E North Daniel I Chasman Lu Qi

Eur J Epidemiol 2020 Jul 7;35(7):685-697. Epub 2020 May 7.

Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, 1440 Canal St, Suite 1724, New Orleans, LA, 70112, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-020-00638-zDOI Listing
July 2020

Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities.

Stroke 2020 Jul 10;51(7):2111-2121. Epub 2020 Jun 10.

GeneSTAR Research Program (L.R.Y., B.G.K., L.C.B., P.A.N.), Johns Hopkins University School of Medicine, Baltimore, MD.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/STROKEAHA.119.027544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365038PMC
July 2020

Association of Factor V Leiden with Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data.

Circulation 2020 Jul 13. Epub 2020 Jul 13.

Institute of Cardiovascular Science and UCL BHF Research Accelerator, Faculty of Population Health Science, University College London, London, UK; Bart's Heart Centre, St Bartholomew's Hospital, London, EC1A2DA, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.119.045526DOI Listing
July 2020

Relationship between fermented dairy consumption, circulating short-chain acylcarnitines and angiographic severity of coronary artery disease.

Nutr Metab Cardiovasc Dis 2020 Jun 8. Epub 2020 Jun 8.

LIFE - Leipzig Research Center for Civilization Diseases, Germany; University Leipzig, Germany; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.numecd.2020.05.031DOI Listing
June 2020

A biomathematical model of human erythropoiesis and iron metabolism.

Sci Rep 2020 May 25;10(1):8602. Epub 2020 May 25.

Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-020-65313-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7248076PMC
May 2020

Genome-wide analysis of carotid plaque burden suggests a role of IL5 in men.

PLoS One 2020 29;15(5):e0233728. Epub 2020 May 29.

Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0233728PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7259763PMC
May 2020

Neutralizing Complement C5a Protects Mice with Pneumococcal Pulmonary Sepsis.

Anesthesiology 2020 04;132(4):795-807

From the Division of Pulmonary Inflammation (H.M.-R., S.-M.W., B.G., J.L., K.H., K.R., E.L., M.W.) the Department of Infectious Diseases and Respiratory Medicine (H.M.-R., U.K., N.S., M.W.), Charité - University Medicine Berlin (Charité - Universitätsmedizin Berlin), corporate member of Free University of Berlin (Freie Universität Berlin), Humboldt University of Berlin (Humboldt-Universität zu Berlin), and Berlin Institute of Health, Berlin, Germany Institute of Anatomy and Cell Biology, Saarland University, Homburg/Saar, Germany (T.T.) Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany (M.S., P.A.) NOXXON Pharma AG, Berlin, Germany (C.M., K.H., S.K., A.V.) Institute of Veterinary Pathology, Free University of Berlin (Freie Universität Berlin), Berlin, Germany (T.C.F., J.H.) German Center for Lung Research, Giessen, Germany (associate members N.S., M.W.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/ALN.0000000000003149DOI Listing
April 2020

Nonobstructive Coronary Artery Disease at Angiography and Gender-Specific Indicators for Cardiovascular Events: 5-Year Follow-Up of the LIFE Heart Study.

J Womens Health (Larchmt) 2020 Mar 26;29(3):338-344. Epub 2019 Nov 26.

Institute of Gender in Medicine (GiM), Center for Cardiovascular Research (CCR), Charité-Universitaetsmedizin Berlin, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/jwh.2019.7730DOI Listing
March 2020

Sepsis-associated acute respiratory distress syndrome in individuals of European ancestry: a genome-wide association study.

Lancet Respir Med 2020 03 23;8(3):258-266. Epub 2020 Jan 23.

Research Unit, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain; Genomics Division, Instituto Tecnológico y de Energías Renovables, Santa Cruz de Tenerife, Spain; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain; Instituto de Tecnologías Biomédicas, Universidad de La Laguna, Santa Cruz de Tenerife, Spain. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2213-2600(19)30368-6DOI Listing
March 2020

Human brain arousal in the resting state: a genome-wide association study.

Mol Psychiatry 2019 11 27;24(11):1599-1609. Epub 2018 Apr 27.

LIFE - Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41380-018-0052-2DOI Listing
November 2019

Genetic Association Study of Eight Steroid Hormones and Implications for Sexual Dimorphism of Coronary Artery Disease.

J Clin Endocrinol Metab 2019 11;104(11):5008-5023

Institute for Medical Informatics, Statistics, and Epidemiology, University of Leipzig, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2019-00757DOI Listing
November 2019

Circulating Oxytocin Is Genetically Determined and Associated With Obesity and Impaired Glucose Tolerance.

J Clin Endocrinol Metab 2019 11;104(11):5621-5632

Medical Department III-Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2019-00643DOI Listing
November 2019

Genetic architecture of subcortical brain structures in 38,851 individuals.

Authors:
Claudia L Satizabal Hieab H H Adams Derrek P Hibar Charles C White Maria J Knol Jason L Stein Markus Scholz Muralidharan Sargurupremraj Neda Jahanshad Gennady V Roshchupkin Albert V Smith Joshua C Bis Xueqiu Jian Michelle Luciano Edith Hofer Alexander Teumer Sven J van der Lee Jingyun Yang Lisa R Yanek Tom V Lee Shuo Li Yanhui Hu Jia Yu Koh John D Eicher Sylvane Desrivières Alejandro Arias-Vasquez Ganesh Chauhan Lavinia Athanasiu Miguel E Rentería Sungeun Kim David Hoehn Nicola J Armstrong Qiang Chen Avram J Holmes Anouk den Braber Iwona Kloszewska Micael Andersson Thomas Espeseth Oliver Grimm Lucija Abramovic Saud Alhusaini Yuri Milaneschi Martina Papmeyer Tomas Axelsson Stefan Ehrlich Roberto Roiz-Santiañez Bernd Kraemer Asta K Håberg Hannah J Jones G Bruce Pike Dan J Stein Allison Stevens Janita Bralten Meike W Vernooij Tamara B Harris Irina Filippi A Veronica Witte Tulio Guadalupe Katharina Wittfeld Thomas H Mosley James T Becker Nhat Trung Doan Saskia P Hagenaars Yasaman Saba Gabriel Cuellar-Partida Najaf Amin Saima Hilal Kwangsik Nho Nazanin Mirza-Schreiber Konstantinos Arfanakis Diane M Becker David Ames Aaron L Goldman Phil H Lee Dorret I Boomsma Simon Lovestone Sudheer Giddaluru Stephanie Le Hellard Manuel Mattheisen Marc M Bohlken Dalia Kasperaviciute Lianne Schmaal Stephen M Lawrie Ingrid Agartz Esther Walton Diana Tordesillas-Gutierrez Gareth E Davies Jean Shin Jonathan C Ipser Louis N Vinke Martine Hoogman Tianye Jia Ralph Burkhardt Marieke Klein Fabrice Crivello Deborah Janowitz Owen Carmichael Unn K Haukvik Benjamin S Aribisala Helena Schmidt Lachlan T Strike Ching-Yu Cheng Shannon L Risacher Benno Pütz Debra A Fleischman Amelia A Assareh Venkata S Mattay Randy L Buckner Patrizia Mecocci Anders M Dale Sven Cichon Marco P Boks Mar Matarin Brenda W J H Penninx Vince D Calhoun M Mallar Chakravarty Andre F Marquand Christine Macare Shahrzad Kharabian Masouleh Jaap Oosterlaan Philippe Amouyel Katrin Hegenscheid Jerome I Rotter Andrew J Schork David C M Liewald Greig I de Zubicaray Tien Yin Wong Li Shen Philipp G Sämann Henry Brodaty Joshua L Roffman Eco J C de Geus Magda Tsolaki Susanne Erk Kristel R van Eijk Gianpiero L Cavalleri Nic J A van der Wee Andrew M McIntosh Randy L Gollub Kazima B Bulayeva Manon Bernard Jennifer S Richards Jayandra J Himali Markus Loeffler Nanda Rommelse Wolfgang Hoffmann Lars T Westlye Maria C Valdés Hernández Narelle K Hansell Theo G M van Erp Christiane Wolf John B J Kwok Bruno Vellas Andreas Heinz Loes M Olde Loohuis Norman Delanty Beng-Choon Ho Christopher R K Ching Elena Shumskaya Baljeet Singh Albert Hofman Dennis van der Meer Georg Homuth Bruce M Psaty Mark E Bastin Grant W Montgomery Tatiana M Foroud Simone Reppermund Jouke-Jan Hottenga Andrew Simmons Andreas Meyer-Lindenberg Wiepke Cahn Christopher D Whelan Marjolein M J van Donkelaar Qiong Yang Norbert Hosten Robert C Green Anbupalam Thalamuthu Sebastian Mohnke Hilleke E Hulshoff Pol Honghuang Lin Clifford R Jack Peter R Schofield Thomas W Mühleisen Pauline Maillard Steven G Potkin Wei Wen Evan Fletcher Arthur W Toga Oliver Gruber Matthew Huentelman George Davey Smith Lenore J Launer Lars Nyberg Erik G Jönsson Benedicto Crespo-Facorro Nastassja Koen Douglas N Greve André G Uitterlinden Daniel R Weinberger Vidar M Steen Iryna O Fedko Nynke A Groenewold Wiro J Niessen Roberto Toro Christophe Tzourio William T Longstreth M Kamran Ikram Jordan W Smoller Marie-Jose van Tol Jessika E Sussmann Tomas Paus Hervé Lemaître Matthias L Schroeter Bernard Mazoyer Ole A Andreassen Florian Holsboer Chantal Depondt Dick J Veltman Jessica A Turner Zdenka Pausova Gunter Schumann Daan van Rooij Srdjan Djurovic Ian J Deary Katie L McMahon Bertram Müller-Myhsok Rachel M Brouwer Hilkka Soininen Massimo Pandolfo Thomas H Wassink Joshua W Cheung Thomas Wolfers Jean-Luc Martinot Marcel P Zwiers Matthias Nauck Ingrid Melle Nicholas G Martin Ryota Kanai Eric Westman René S Kahn Sanjay M Sisodiya Tonya White Arvin Saremi Hans van Bokhoven Han G Brunner Henry Völzke Margaret J Wright Dennis van 't Ent Markus M Nöthen Roel A Ophoff Jan K Buitelaar Guillén Fernández Perminder S Sachdev Marcella Rietschel Neeltje E M van Haren Simon E Fisher Alexa S Beiser Clyde Francks Andrew J Saykin Karen A Mather Nina Romanczuk-Seiferth Catharina A Hartman Anita L DeStefano Dirk J Heslenfeld Michael W Weiner Henrik Walter Pieter J Hoekstra Paul A Nyquist Barbara Franke David A Bennett Hans J Grabe Andrew D Johnson Christopher Chen Cornelia M van Duijn Oscar L Lopez Myriam Fornage Joanna M Wardlaw Reinhold Schmidt Charles DeCarli Philip L De Jager Arno Villringer Stéphanie Debette Vilmundur Gudnason Sarah E Medland Joshua M Shulman Paul M Thompson Sudha Seshadri M Arfan Ikram

Nat Genet 2019 11 21;51(11):1624-1636. Epub 2019 Oct 21.

Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-019-0511-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7055269PMC
November 2019

Clinical and lifestyle related factors influencing whole blood metabolite levels - A comparative analysis of three large cohorts.

Mol Metab 2019 11 17;29:76-85. Epub 2019 Aug 17.

Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany; LIFE - Leipzig Research Center for Civilization Diseases, Leipzig University, Leipzig, Germany; IFB Adiposity Diseases, University Hospital Leipzig, Leipzig, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molmet.2019.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734104PMC
November 2019

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels.

Authors:
Adrienne Tin Jonathan Marten Victoria L Halperin Kuhns Yong Li Matthias Wuttke Holger Kirsten Karsten B Sieber Chengxiang Qiu Mathias Gorski Zhi Yu Ayush Giri Gardar Sveinbjornsson Man Li Audrey Y Chu Anselm Hoppmann Luke J O'Connor Bram Prins Teresa Nutile Damia Noce Masato Akiyama Massimiliano Cocca Sahar Ghasemi Peter J van der Most Katrin Horn Yizhe Xu Christian Fuchsberger Sanaz Sedaghat Saima Afaq Najaf Amin Johan Ärnlöv Stephan J L Bakker Nisha Bansal Daniela Baptista Sven Bergmann Mary L Biggs Ginevra Biino Eric Boerwinkle Erwin P Bottinger Thibaud S Boutin Marco Brumat Ralph Burkhardt Eric Campana Archie Campbell Harry Campbell Robert J Carroll Eulalia Catamo John C Chambers Marina Ciullo Maria Pina Concas Josef Coresh Tanguy Corre Daniele Cusi Sala Cinzia Felicita Martin H de Borst Alessandro De Grandi Renée de Mutsert Aiko P J de Vries Graciela Delgado Ayşe Demirkan Olivier Devuyst Katalin Dittrich Kai-Uwe Eckardt Georg Ehret Karlhans Endlich Michele K Evans Ron T Gansevoort Paolo Gasparini Vilmantas Giedraitis Christian Gieger Giorgia Girotto Martin Gögele Scott D Gordon Daniel F Gudbjartsson Vilmundur Gudnason Toomas Haller Pavel Hamet Tamara B Harris Caroline Hayward Andrew A Hicks Edith Hofer Hilma Holm Wei Huang Nina Hutri-Kähönen Shih-Jen Hwang M Arfan Ikram Raychel M Lewis Erik Ingelsson Johanna Jakobsdottir Ingileif Jonsdottir Helgi Jonsson Peter K Joshi Navya Shilpa Josyula Bettina Jung Mika Kähönen Yoichiro Kamatani Masahiro Kanai Shona M Kerr Wieland Kiess Marcus E Kleber Wolfgang Koenig Jaspal S Kooner Antje Körner Peter Kovacs Bernhard K Krämer Florian Kronenberg Michiaki Kubo Brigitte Kühnel Martina La Bianca Leslie A Lange Benjamin Lehne Terho Lehtimäki Jun Liu Markus Loeffler Ruth J F Loos Leo-Pekka Lyytikäinen Reedik Magi Anubha Mahajan Nicholas G Martin Winfried März Deborah Mascalzoni Koichi Matsuda Christa Meisinger Thomas Meitinger Andres Metspalu Yuri Milaneschi Christopher J O'Donnell Otis D Wilson J Michael Gaziano Pashupati P Mishra Karen L Mohlke Nina Mononen Grant W Montgomery Dennis O Mook-Kanamori Martina Müller-Nurasyid Girish N Nadkarni Mike A Nalls Matthias Nauck Kjell Nikus Boting Ning Ilja M Nolte Raymond Noordam Jeffrey R O'Connell Isleifur Olafsson Sandosh Padmanabhan Brenda W J H Penninx Thomas Perls Annette Peters Mario Pirastu Nicola Pirastu Giorgio Pistis Ozren Polasek Belen Ponte David J Porteous Tanja Poulain Michael H Preuss Ton J Rabelink Laura M Raffield Olli T Raitakari Rainer Rettig Myriam Rheinberger Kenneth M Rice Federica Rizzi Antonietta Robino Igor Rudan Alena Krajcoviechova Renata Cifkova Rico Rueedi Daniela Ruggiero Kathleen A Ryan Yasaman Saba Erika Salvi Helena Schmidt Reinhold Schmidt Christian M Shaffer Albert V Smith Blair H Smith Cassandra N Spracklen Konstantin Strauch Michael Stumvoll Patrick Sulem Salman M Tajuddin Andrej Teren Joachim Thiery Chris H L Thio Unnur Thorsteinsdottir Daniela Toniolo Anke Tönjes Johanne Tremblay André G Uitterlinden Simona Vaccargiu Pim van der Harst Cornelia M van Duijn Niek Verweij Uwe Völker Peter Vollenweider Gerard Waeber Melanie Waldenberger John B Whitfield Sarah H Wild James F Wilson Qiong Yang Weihua Zhang Alan B Zonderman Murielle Bochud James G Wilson Sarah A Pendergrass Kevin Ho Afshin Parsa Peter P Pramstaller Bruce M Psaty Carsten A Böger Harold Snieder Adam S Butterworth Yukinori Okada Todd L Edwards Kari Stefansson Katalin Susztak Markus Scholz Iris M Heid Adriana M Hung Alexander Teumer Cristian Pattaro Owen M Woodward Veronique Vitart Anna Köttgen

Nat Genet 2019 10 2;51(10):1459-1474. Epub 2019 Oct 2.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-019-0504-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858555PMC
October 2019

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.

Authors:
Alexander Teumer Yong Li Sahar Ghasemi Bram P Prins Matthias Wuttke Tobias Hermle Ayush Giri Karsten B Sieber Chengxiang Qiu Holger Kirsten Adrienne Tin Audrey Y Chu Nisha Bansal Mary F Feitosa Lihua Wang Jin-Fang Chai Massimiliano Cocca Christian Fuchsberger Mathias Gorski Anselm Hoppmann Katrin Horn Man Li Jonathan Marten Damia Noce Teresa Nutile Sanaz Sedaghat Gardar Sveinbjornsson Bamidele O Tayo Peter J van der Most Yizhe Xu Zhi Yu Lea Gerstner Johan Ärnlöv Stephan J L Bakker Daniela Baptista Mary L Biggs Eric Boerwinkle Hermann Brenner Ralph Burkhardt Robert J Carroll Miao-Li Chee Miao-Ling Chee Mengmeng Chen Ching-Yu Cheng James P Cook Josef Coresh Tanguy Corre John Danesh Martin H de Borst Alessandro De Grandi Renée de Mutsert Aiko P J de Vries Frauke Degenhardt Katalin Dittrich Jasmin Divers Kai-Uwe Eckardt Georg Ehret Karlhans Endlich Janine F Felix Oscar H Franco Andre Franke Barry I Freedman Sandra Freitag-Wolf Ron T Gansevoort Vilmantas Giedraitis Martin Gögele Franziska Grundner-Culemann Daniel F Gudbjartsson Vilmundur Gudnason Pavel Hamet Tamara B Harris Andrew A Hicks Hilma Holm Valencia Hui Xian Foo Shih-Jen Hwang M Arfan Ikram Erik Ingelsson Vincent W V Jaddoe Johanna Jakobsdottir Navya Shilpa Josyula Bettina Jung Mika Kähönen Chiea-Chuen Khor Wieland Kiess Wolfgang Koenig Antje Körner Peter Kovacs Holly Kramer Bernhard K Krämer Florian Kronenberg Leslie A Lange Carl D Langefeld Jeannette Jen-Mai Lee Terho Lehtimäki Wolfgang Lieb Su-Chi Lim Lars Lind Cecilia M Lindgren Jianjun Liu Markus Loeffler Leo-Pekka Lyytikäinen Anubha Mahajan Joseph C Maranville Deborah Mascalzoni Barbara McMullen Christa Meisinger Thomas Meitinger Kozeta Miliku Dennis O Mook-Kanamori Martina Müller-Nurasyid Josyf C Mychaleckyj Matthias Nauck Kjell Nikus Boting Ning Raymond Noordam Jeffrey O' Connell Isleifur Olafsson Nicholette D Palmer Annette Peters Anna I Podgornaia Belen Ponte Tanja Poulain Peter P Pramstaller Ton J Rabelink Laura M Raffield Dermot F Reilly Rainer Rettig Myriam Rheinberger Kenneth M Rice Fernando Rivadeneira Heiko Runz Kathleen A Ryan Charumathi Sabanayagam Kai-Uwe Saum Ben Schöttker Christian M Shaffer Yuan Shi Albert V Smith Konstantin Strauch Michael Stumvoll Benjamin B Sun Silke Szymczak E-Shyong Tai Nicholas Y Q Tan Kent D Taylor Andrej Teren Yih-Chung Tham Joachim Thiery Chris H L Thio Hauke Thomsen Unnur Thorsteinsdottir Anke Tönjes Johanne Tremblay André G Uitterlinden Pim van der Harst Niek Verweij Suzanne Vogelezang Uwe Völker Melanie Waldenberger Chaolong Wang Otis D Wilson Charlene Wong Tien-Yin Wong Qiong Yang Masayuki Yasuda Shreeram Akilesh Murielle Bochud Carsten A Böger Olivier Devuyst Todd L Edwards Kevin Ho Andrew P Morris Afshin Parsa Sarah A Pendergrass Bruce M Psaty Jerome I Rotter Kari Stefansson James G Wilson Katalin Susztak Harold Snieder Iris M Heid Markus Scholz Adam S Butterworth Adriana M Hung Cristian Pattaro Anna Köttgen

Nat Commun 2019 09 11;10(1):4130. Epub 2019 Sep 11.

Institute of Genetic Epidemiology, Department of Biometry, Epidemiology and Medical Bioinformatics, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-11576-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739370PMC
September 2019

Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study.

Authors:
Tao Huang Tiange Wang Yan Zheng Christina Ellervik Xiang Li Meng Gao Zhe Fang Jin-Fang Chai Tarun Veer S Ahluwalia Yujie Wang Trudy Voortman Raymond Noordam Alexis Frazier-Wood Markus Scholz Emily Sonestedt Masato Akiyama Rajkumar Dorajoo Ang Zhou Tuomas O Kilpeläinen Marcus E Kleber Sarah R Crozier Keith M Godfrey Rozenn Lemaitre Janine F Felix Yuan Shi Preeti Gupta Chiea-Chuen Khor Terho Lehtimäki Carol A Wang Carla M T Tiesler Elisabeth Thiering Marie Standl Peter Rzehak Eirini Marouli Meian He Cécile Lecoeur Dolores Corella Chao-Qiang Lai Luis A Moreno Niina Pitkänen Colin A Boreham Tao Zhang Seang Mei Saw Paul M Ridker Mariaelisa Graff Frank J A van Rooij Andre G Uitterlinden Albert Hofman Diana van Heemst Frits R Rosendaal Renée de Mutsert Ralph Burkhardt Christina-Alexandra Schulz Ulrika Ericson Yoichiro Kamatani Jian-Min Yuan Chris Power Torben Hansen Thorkild I A Sørensen Anne Tjønneland Kim Overvad Graciela Delgado Cyrus Cooper Luc Djousse Fernando Rivadeneira Karen Jameson Wanting Zhao Jianjun Liu Nanette R Lee Olli Raitakari Mika Kähönen Jorma Viikari Veit Grote Jean-Paul Langhendries Berthold Koletzko Joaquin Escribano Elvira Verduci George Dedoussis Caizheng Yu Yih Chung Tham Blanche Lim Sing Hui Lim Philippe Froguel Beverley Balkau Nadia R Fink Rebecca K Vinding Astrid Sevelsted Hans Bisgaard Oscar Coltell Jean Dallongeville Frédéric Gottrand Katja Pahkala Harri Niinikoski Elina Hyppönen Oluf Pedersen Winfried März Hazel Inskip Vincent W V Jaddoe Elaine Dennison Tien Yin Wong Charumathi Sabanayagam E-Shyong Tai Karen L Mohlke David A Mackey Dariusz Gruszfeld Panagiotis Deloukas Katherine L Tucker Frédéric Fumeron Klaus Bønnelykke Peter Rossing Ramon Estruch Jose M Ordovas Donna K Arnett Aline Meirhaeghe Philippe Amouyel Ching-Yu Cheng Xueling Sim Yik Ying Teo Rob M van Dam Woon-Puay Koh Marju Orho-Melander Markus Loeffler Michiaki Kubo Joachim Thiery Dennis O Mook-Kanamori Dariush Mozaffarian Bruce M Psaty Oscar H Franco Tangchun Wu Kari E North George Davey Smith Jorge E Chavarro Daniel I Chasman Lu Qi

JAMA Netw Open 2019 09 4;2(9):e1910915. Epub 2019 Sep 4.

Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamanetworkopen.2019.10915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755534PMC
September 2019

A catalog of genetic loci associated with kidney function from analyses of a million individuals.

Authors:
Matthias Wuttke Yong Li Man Li Karsten B Sieber Mary F Feitosa Mathias Gorski Adrienne Tin Lihua Wang Audrey Y Chu Anselm Hoppmann Holger Kirsten Ayush Giri Jin-Fang Chai Gardar Sveinbjornsson Bamidele O Tayo Teresa Nutile Christian Fuchsberger Jonathan Marten Massimiliano Cocca Sahar Ghasemi Yizhe Xu Katrin Horn Damia Noce Peter J van der Most Sanaz Sedaghat Zhi Yu Masato Akiyama Saima Afaq Tarunveer S Ahluwalia Peter Almgren Najaf Amin Johan Ärnlöv Stephan J L Bakker Nisha Bansal Daniela Baptista Sven Bergmann Mary L Biggs Ginevra Biino Michael Boehnke Eric Boerwinkle Mathilde Boissel Erwin P Bottinger Thibaud S Boutin Hermann Brenner Marco Brumat Ralph Burkhardt Adam S Butterworth Eric Campana Archie Campbell Harry Campbell Mickaël Canouil Robert J Carroll Eulalia Catamo John C Chambers Miao-Ling Chee Miao-Li Chee Xu Chen Ching-Yu Cheng Yurong Cheng Kaare Christensen Renata Cifkova Marina Ciullo Maria Pina Concas James P Cook Josef Coresh Tanguy Corre Cinzia Felicita Sala Daniele Cusi John Danesh E Warwick Daw Martin H de Borst Alessandro De Grandi Renée de Mutsert Aiko P J de Vries Frauke Degenhardt Graciela Delgado Ayse Demirkan Emanuele Di Angelantonio Katalin Dittrich Jasmin Divers Rajkumar Dorajoo Kai-Uwe Eckardt Georg Ehret Paul Elliott Karlhans Endlich Michele K Evans Janine F Felix Valencia Hui Xian Foo Oscar H Franco Andre Franke Barry I Freedman Sandra Freitag-Wolf Yechiel Friedlander Philippe Froguel Ron T Gansevoort He Gao Paolo Gasparini J Michael Gaziano Vilmantas Giedraitis Christian Gieger Giorgia Girotto Franco Giulianini Martin Gögele Scott D Gordon Daniel F Gudbjartsson Vilmundur Gudnason Toomas Haller Pavel Hamet Tamara B Harris Catharina A Hartman Caroline Hayward Jacklyn N Hellwege Chew-Kiat Heng Andrew A Hicks Edith Hofer Wei Huang Nina Hutri-Kähönen Shih-Jen Hwang M Arfan Ikram Olafur S Indridason Erik Ingelsson Marcus Ising Vincent W V Jaddoe Johanna Jakobsdottir Jost B Jonas Peter K Joshi Navya Shilpa Josyula Bettina Jung Mika Kähönen Yoichiro Kamatani Candace M Kammerer Masahiro Kanai Mika Kastarinen Shona M Kerr Chiea-Chuen Khor Wieland Kiess Marcus E Kleber Wolfgang Koenig Jaspal S Kooner Antje Körner Peter Kovacs Aldi T Kraja Alena Krajcoviechova Holly Kramer Bernhard K Krämer Florian Kronenberg Michiaki Kubo Brigitte Kühnel Mikko Kuokkanen Johanna Kuusisto Martina La Bianca Markku Laakso Leslie A Lange Carl D Langefeld Jeannette Jen-Mai Lee Benjamin Lehne Terho Lehtimäki Wolfgang Lieb Su-Chi Lim Lars Lind Cecilia M Lindgren Jun Liu Jianjun Liu Markus Loeffler Ruth J F Loos Susanne Lucae Mary Ann Lukas Leo-Pekka Lyytikäinen Reedik Mägi Patrik K E Magnusson Anubha Mahajan Nicholas G Martin Jade Martins Winfried März Deborah Mascalzoni Koichi Matsuda Christa Meisinger Thomas Meitinger Olle Melander Andres Metspalu Evgenia K Mikaelsdottir Yuri Milaneschi Kozeta Miliku Pashupati P Mishra Karen L Mohlke Nina Mononen Grant W Montgomery Dennis O Mook-Kanamori Josyf C Mychaleckyj Girish N Nadkarni Mike A Nalls Matthias Nauck Kjell Nikus Boting Ning Ilja M Nolte Raymond Noordam Jeffrey O'Connell Michelle L O'Donoghue Isleifur Olafsson Albertine J Oldehinkel Marju Orho-Melander Willem H Ouwehand Sandosh Padmanabhan Nicholette D Palmer Runolfur Palsson Brenda W J H Penninx Thomas Perls Markus Perola Mario Pirastu Nicola Pirastu Giorgio Pistis Anna I Podgornaia Ozren Polasek Belen Ponte David J Porteous Tanja Poulain Peter P Pramstaller Michael H Preuss Bram P Prins Michael A Province Ton J Rabelink Laura M Raffield Olli T Raitakari Dermot F Reilly Rainer Rettig Myriam Rheinberger Kenneth M Rice Paul M Ridker Fernando Rivadeneira Federica Rizzi David J Roberts Antonietta Robino Peter Rossing Igor Rudan Rico Rueedi Daniela Ruggiero Kathleen A Ryan Yasaman Saba Charumathi Sabanayagam Veikko Salomaa Erika Salvi Kai-Uwe Saum Helena Schmidt Reinhold Schmidt Ben Schöttker Christina-Alexandra Schulz Nicole Schupf Christian M Shaffer Yuan Shi Albert V Smith Blair H Smith Nicole Soranzo Cassandra N Spracklen Konstantin Strauch Heather M Stringham Michael Stumvoll Per O Svensson Silke Szymczak E-Shyong Tai Salman M Tajuddin Nicholas Y Q Tan Kent D Taylor Andrej Teren Yih-Chung Tham Joachim Thiery Chris H L Thio Hauke Thomsen Gudmar Thorleifsson Daniela Toniolo Anke Tönjes Johanne Tremblay Ioanna Tzoulaki André G Uitterlinden Simona Vaccargiu Rob M van Dam Pim van der Harst Cornelia M van Duijn Digna R Velez Edward Niek Verweij Suzanne Vogelezang Uwe Völker Peter Vollenweider Gerard Waeber Melanie Waldenberger Lars Wallentin Ya Xing Wang Chaolong Wang Dawn M Waterworth Wen Bin Wei Harvey White John B Whitfield Sarah H Wild James F Wilson Mary K Wojczynski Charlene Wong Tien-Yin Wong Liang Xu Qiong Yang Masayuki Yasuda Laura M Yerges-Armstrong Weihua Zhang Alan B Zonderman Jerome I Rotter Murielle Bochud Bruce M Psaty Veronique Vitart James G Wilson Abbas Dehghan Afshin Parsa Daniel I Chasman Kevin Ho Andrew P Morris Olivier Devuyst Shreeram Akilesh Sarah A Pendergrass Xueling Sim Carsten A Böger Yukinori Okada Todd L Edwards Harold Snieder Kari Stefansson Adriana M Hung Iris M Heid Markus Scholz Alexander Teumer Anna Köttgen Cristian Pattaro

Nat Genet 2019 06 31;51(6):957-972. Epub 2019 May 31.

Eurac Research, Institute for Biomedicine (affiliated with the University of Lübeck), Bolzano, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41588-019-0407-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698888PMC
June 2019

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

Authors:
Gail Davies Max Lam Sarah E Harris Joey W Trampush Michelle Luciano W David Hill Saskia P Hagenaars Stuart J Ritchie Riccardo E Marioni Chloe Fawns-Ritchie David C M Liewald Judith A Okely Ari V Ahola-Olli Catriona L K Barnes Lars Bertram Joshua C Bis Katherine E Burdick Andrea Christoforou Pamela DeRosse Srdjan Djurovic Thomas Espeseth Stella Giakoumaki Sudheer Giddaluru Daniel E Gustavson Caroline Hayward Edith Hofer M Arfan Ikram Robert Karlsson Emma Knowles Jari Lahti Markus Leber Shuo Li Karen A Mather Ingrid Melle Derek Morris Christopher Oldmeadow Teemu Palviainen Antony Payton Raha Pazoki Katja Petrovic Chandra A Reynolds Muralidharan Sargurupremraj Markus Scholz Jennifer A Smith Albert V Smith Natalie Terzikhan Anbupalam Thalamuthu Stella Trompet Sven J van der Lee Erin B Ware B Gwen Windham Margaret J Wright Jingyun Yang Jin Yu David Ames Najaf Amin Philippe Amouyel Ole A Andreassen Nicola J Armstrong Amelia A Assareh John R Attia Deborah Attix Dimitrios Avramopoulos David A Bennett Anne C Böhmer Patricia A Boyle Henry Brodaty Harry Campbell Tyrone D Cannon Elizabeth T Cirulli Eliza Congdon Emily Drabant Conley Janie Corley Simon R Cox Anders M Dale Abbas Dehghan Danielle Dick Dwight Dickinson Johan G Eriksson Evangelos Evangelou Jessica D Faul Ian Ford Nelson A Freimer He Gao Ina Giegling Nathan A Gillespie Scott D Gordon Rebecca F Gottesman Michael E Griswold Vilmundur Gudnason Tamara B Harris Annette M Hartmann Alex Hatzimanolis Gerardo Heiss Elizabeth G Holliday Peter K Joshi Mika Kähönen Sharon L R Kardia Ida Karlsson Luca Kleineidam David S Knopman Nicole A Kochan Bettina Konte John B Kwok Stephanie Le Hellard Teresa Lee Terho Lehtimäki Shu-Chen Li Christina M Lill Tian Liu Marisa Koini Edythe London Will T Longstreth Oscar L Lopez Anu Loukola Tobias Luck Astri J Lundervold Anders Lundquist Leo-Pekka Lyytikäinen Nicholas G Martin Grant W Montgomery Alison D Murray Anna C Need Raymond Noordam Lars Nyberg William Ollier Goran Papenberg Alison Pattie Ozren Polasek Russell A Poldrack Bruce M Psaty Simone Reppermund Steffi G Riedel-Heller Richard J Rose Jerome I Rotter Panos Roussos Suvi P Rovio Yasaman Saba Fred W Sabb Perminder S Sachdev Claudia L Satizabal Matthias Schmid Rodney J Scott Matthew A Scult Jeannette Simino P Eline Slagboom Nikolaos Smyrnis Aïcha Soumaré Nikos C Stefanis David J Stott Richard E Straub Kjetil Sundet Adele M Taylor Kent D Taylor Ioanna Tzoulaki Christophe Tzourio André Uitterlinden Veronique Vitart Aristotle N Voineskos Jaakko Kaprio Michael Wagner Holger Wagner Leonie Weinhold K Hoyan Wen Elisabeth Widen Qiong Yang Wei Zhao Hieab H H Adams Dan E Arking Robert M Bilder Panos Bitsios Eric Boerwinkle Ornit Chiba-Falek Aiden Corvin Philip L De Jager Stéphanie Debette Gary Donohoe Paul Elliott Annette L Fitzpatrick Michael Gill David C Glahn Sara Hägg Narelle K Hansell Ahmad R Hariri M Kamran Ikram J Wouter Jukema Eero Vuoksimaa Matthew C Keller William S Kremen Lenore Launer Ulman Lindenberger Aarno Palotie Nancy L Pedersen Neil Pendleton David J Porteous Katri Räikkönen Olli T Raitakari Alfredo Ramirez Ivar Reinvang Igor Rudan Dan Rujescu Reinhold Schmidt Helena Schmidt Peter W Schofield Peter R Schofield John M Starr Vidar M Steen Julian N Trollor Steven T Turner Cornelia M Van Duijn Arno Villringer Daniel R Weinberger David R Weir James F Wilson Anil Malhotra Andrew M McIntosh Catharine R Gale Sudha Seshadri Thomas H Mosley Jan Bressler Todd Lencz Ian J Deary

Nat Commun 2019 May 1;10(1):2068. Epub 2019 May 1.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-019-10160-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494826PMC
May 2019

Circulating Adipokine VASPIN Is Associated with Serum Lipid Profiles in Humans.

Lipids 2019 04 18;54(4):203-210. Epub 2019 Mar 18.

Department of Medicine, Division of Endocrinology and Nephrology, University of Leipzig, Liebigstrasse 21, 04103, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/lipd.12139DOI Listing
April 2019

Subsequent Event Risk in Individuals With Established Coronary Heart Disease.

Authors:
Riyaz S Patel Vinicius Tragante Amand F Schmidt Raymond O McCubrey Michael V Holmes Laurence J Howe Kenan Direk Axel Åkerblom Karin Leander Salim S Virani Karol A Kaminski Jochen D Muehlschlegel Hooman Allayee Peter Almgren Maris Alver Ekaterina V Baranova Hassan Behloui Bram Boeckx Peter S Braund Lutz P Breitling Graciela Delgado Nubia E Duarte Marie-Pierre Dubé Line Dufresne Niclas Eriksson Luisa Foco Markus Scholz Crystel M Gijsberts Charlotte Glinge Yan Gong Jaana Hartiala Mahyar Heydarpour Jaroslav A Hubacek Marcus Kleber Daniel Kofink Salma Kotti Pekka Kuukasjärvi Vei-Vei Lee Andreas Leiherer Petra A Lenzini Daniel Levin Leo-Pekka Lyytikäinen Nicola Martinelli Ute Mons Christopher P Nelson Kjell Nikus Anna P Pilbrow Rafal Ploski Yan V Sun Michael W T Tanck W H Wilson Tang Stella Trompet Sander W van der Laan Jessica Van Setten Ragnar O Vilmundarson Chiara Viviani Anselmi Efthymia Vlachopoulou Lawien Al Ali Eric Boerwinkle Carlo Briguori John F Carlquist Kathryn F Carruthers Gavino Casu John Deanfield Panos Deloukas Frank Dudbridge Thomas Engstrøm Natalie Fitzpatrick Kim Fox Bruna Gigante Stefan James Marja-Liisa Lokki Paulo A Lotufo Nicola Marziliano Ify R Mordi Joseph B Muhlestein Christopher Newton-Cheh Jan Pitha Christoph H Saely Ayman Samman-Tahhan Pratik B Sandesara Andrej Teren Adam Timmis Frans Van de Werf Els Wauters Arthur A M Wilde Ian Ford David J Stott Ale Algra Maria G Andreassi Diego Ardissino Benoit J Arsenault Christie M Ballantyne Thomas O Bergmeijer Connie R Bezzina Simon C Body Eric H Boersma Peter Bogaty Michiel L Bots Hermann Brenner Jasper J Brugts Ralph Burkhardt Clara Carpeggiani Gianluigi Condorelli Rhonda M Cooper-DeHoff Sharon Cresci Nicolas Danchin Ulf de Faire Robert N Doughty Heinz Drexel James C Engert Keith A A Fox Domenico Girelli Diederick E Grobbee Emil Hagström Stanley L Hazen Claes Held Harry Hemingway Imo E Hoefer G Kees Hovingh Reza Jabbari Julie A Johnson J Wouter Jukema Marcin P Kaczor Mika Kähönen Jiri Kettner Marek Kiliszek Olaf H Klungel Bo Lagerqvist Diether Lambrechts Jari O Laurikka Terho Lehtimäki Daniel Lindholm B K Mahmoodi Anke H Maitland-van der Zee Ruth McPherson Olle Melander Andres Metspalu Anna Niemcunowicz-Janica Oliviero Olivieri Grzegorz Opolski Colin N Palmer Gerard Pasterkamp Carl J Pepine Alexandre C Pereira Louise Pilote Arshed A Quyyumi A Mark Richards Marek Sanak Agneta Siegbahn Tabassome Simon Juha Sinisalo J Gustav Smith John A Spertus Steen Stender Alexandre F R Stewart Wojciech Szczeklik Anna Szpakowicz Jean-Claude Tardif Jurriën M Ten Berg Jacob Tfelt-Hansen George Thanassoulis Joachim Thiery Christian Torp-Pedersen Yolanda van der Graaf Frank L J Visseren Johannes Waltenberger Peter E Weeke Pim Van der Harst Chim C Lang Naveed Sattar Vicky A Cameron Jeffrey L Anderson James M Brophy Guillaume Pare Benjamin D Horne Winfried März Lars Wallentin Nilesh J Samani Aroon D Hingorani Folkert W Asselbergs

Circ Genom Precis Med 2019 04 21;12(4):e002470. Epub 2019 Mar 21.

Institute of Health Informatics (N.F., A. Timmis, H.H., F.W.A.), Faculty of Population Health Science, University College London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCGEN.119.002470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629546PMC
April 2019

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events.

Authors:
Riyaz S Patel Amand F Schmidt Vinicius Tragante Raymond O McCubrey Michael V Holmes Laurence J Howe Kenan Direk Axel Åkerblom Karin Leander Salim S Virani Karol A Kaminski Jochen D Muehlschlegel Marie-Pierre Dubé Hooman Allayee Peter Almgren Maris Alver Ekaterina V Baranova Hassan Behlouli Bram Boeckx Peter S Braund Lutz P Breitling Graciela Delgado Nubia E Duarte Line Dufresne Niclas Eriksson Luisa Foco Crystel M Gijsberts Yan Gong Jaana Hartiala Mahyar Heydarpour Jaroslav A Hubacek Marcus Kleber Daniel Kofink Pekka Kuukasjärvi Vei-Vei Lee Andreas Leiherer Petra A Lenzini Daniel Levin Leo-Pekka Lyytikäinen Nicola Martinelli Ute Mons Christopher P Nelson Kjell Nikus Anna P Pilbrow Rafal Ploski Yan V Sun Michael W T Tanck W H Wilson Tang Stella Trompet Sander W van der Laan Jessica van Setten Ragnar O Vilmundarson Chiara Viviani Anselmi Efthymia Vlachopoulou Eric Boerwinkle Carlo Briguori John F Carlquist Kathryn F Carruthers Gavino Casu John Deanfield Panos Deloukas Frank Dudbridge Natalie Fitzpatrick Bruna Gigante Stefan James Marja-Liisa Lokki Paulo A Lotufo Nicola Marziliano Ify R Mordi Joseph B Muhlestein Chris Newton Cheh Jan Pitha Christoph H Saely Ayman Samman-Tahhan Pratik B Sandesara Andrej Teren Adam Timmis Frans Van de Werf Els Wauters Arthur A M Wilde Ian Ford David J Stott Ale Algra Maria G Andreassi Diego Ardissino Benoit J Arsenault Christie M Ballantyne Thomas O Bergmeijer Connie R Bezzina Simon C Body Peter Bogaty Gert J de Borst Hermann Brenner Ralph Burkhardt Clara Carpeggiani Gianluigi Condorelli Rhonda M Cooper-DeHoff Sharon Cresci Ulf de Faire Robert N Doughty Heinz Drexel James C Engert Keith A A Fox Domenico Girelli Emil Hagström Stanley L Hazen Claes Held Harry Hemingway Imo E Hoefer G Kees Hovingh Julie A Johnson Pim A de Jong J Wouter Jukema Marcin P Kaczor Mika Kähönen Jiri Kettner Marek Kiliszek Olaf H Klungel Bo Lagerqvist Diether Lambrechts Jari O Laurikka Terho Lehtimäki Daniel Lindholm Bakhtawar K Mahmoodi Anke H Maitland-van der Zee Ruth McPherson Olle Melander Andres Metspalu Witold Pepinski Oliviero Olivieri Grzegorz Opolski Colin N Palmer Gerard Pasterkamp Carl J Pepine Alexandre C Pereira Louise Pilote Arshed A Quyyumi A Mark Richards Marek Sanak Markus Scholz Agneta Siegbahn Juha Sinisalo J Gustav Smith John A Spertus Alexandre F R Stewart Wojciech Szczeklik Anna Szpakowicz Jurriën M Ten Berg George Thanassoulis Joachim Thiery Yolanda van der Graaf Frank L J Visseren Johannes Waltenberger Pim Van der Harst Jean-Claude Tardif Naveed Sattar Chim C Lang Guillaume Pare James M Brophy Jeffrey L Anderson Winfried März Lars Wallentin Vicky A Cameron Benjamin D Horne Nilesh J Samani Aroon D Hingorani Folkert W Asselbergs

Circ Genom Precis Med 2019 04 21;12(4):e002471. Epub 2019 Mar 21.

Institute of Cardiovascular Science, Faculty of Population Health Science (R.S.P., A.F.S., L.J.H., K.D., J.D., A.D.H., F.W.A.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCGEN.119.002471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625876PMC
April 2019

Modeling individual time courses of thrombopoiesis during multi-cyclic chemotherapy.

PLoS Comput Biol 2019 03 6;15(3):e1006775. Epub 2019 Mar 6.

Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pcbi.1006775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422316PMC
March 2019

Plasma levels of apolipoproteins C-III, A-IV, and E are independently associated with stable atherosclerotic cardiovascular disease.

Atherosclerosis 2019 02 9;281:17-24. Epub 2018 Nov 9.

LIFE -Leipzig Research Center for Civilization Diseases, Leipzig University, Philipp-Rosenthal-Strasse 27, 04103 Leipzig, Germany; Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Paul-List-Strasse 13-15, 04103 Leipzig, Germany. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00219150183146
Publisher Site
http://dx.doi.org/10.1016/j.atherosclerosis.2018.11.006DOI Listing
February 2019

Cyclin dependent kinase inhibitor 1 C is a female-specific marker of left ventricular function after acute myocardial infarction.

Int J Cardiol 2019 Jan 10;274:319-325. Epub 2018 Jul 10.

Cardiovascular Research Unit, Luxembourg Institute of Health, Luxembourg. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2018.07.042DOI Listing
January 2019

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.

Authors:
Nora Franceschini Claudia Giambartolomei Paul S de Vries Chris Finan Joshua C Bis Rachael P Huntley Ruth C Lovering Salman M Tajuddin Thomas W Winkler Misa Graff Maryam Kavousi Caroline Dale Albert V Smith Edith Hofer Elisabeth M van Leeuwen Ilja M Nolte Lingyi Lu Markus Scholz Muralidharan Sargurupremraj Niina Pitkänen Oscar Franzén Peter K Joshi Raymond Noordam Riccardo E Marioni Shih-Jen Hwang Solomon K Musani Ulf Schminke Walter Palmas Aaron Isaacs Adolfo Correa Alan B Zonderman Albert Hofman Alexander Teumer Amanda J Cox André G Uitterlinden Andrew Wong Andries J Smit Anne B Newman Annie Britton Arno Ruusalepp Bengt Sennblad Bo Hedblad Bogdan Pasaniuc Brenda W Penninx Carl D Langefeld Christina L Wassel Christophe Tzourio Cristiano Fava Damiano Baldassarre Daniel H O'Leary Daniel Teupser Diana Kuh Elena Tremoli Elmo Mannarino Enzo Grossi Eric Boerwinkle Eric E Schadt Erik Ingelsson Fabrizio Veglia Fernando Rivadeneira Frank Beutner Ganesh Chauhan Gerardo Heiss Harold Snieder Harry Campbell Henry Völzke Hugh S Markus Ian J Deary J Wouter Jukema Jacqueline de Graaf Jacqueline Price Janne Pott Jemma C Hopewell Jingjing Liang Joachim Thiery Jorgen Engmann Karl Gertow Kenneth Rice Kent D Taylor Klodian Dhana Lambertus A L M Kiemeney Lars Lind Laura M Raffield Lenore J Launer Lesca M Holdt Marcus Dörr Martin Dichgans Matthew Traylor Matthias Sitzer Meena Kumari Mika Kivimaki Mike A Nalls Olle Melander Olli Raitakari Oscar H Franco Oscar L Rueda-Ochoa Panos Roussos Peter H Whincup Philippe Amouyel Philippe Giral Pramod Anugu Quenna Wong Rainer Malik Rainer Rauramaa Ralph Burkhardt Rebecca Hardy Reinhold Schmidt Renée de Mutsert Richard W Morris Rona J Strawbridge S Goya Wannamethee Sara Hägg Sonia Shah Stela McLachlan Stella Trompet Sudha Seshadri Sudhir Kurl Susan R Heckbert Susan Ring Tamara B Harris Terho Lehtimäki Tessel E Galesloot Tina Shah Ulf de Faire Vincent Plagnol Wayne D Rosamond Wendy Post Xiaofeng Zhu Xiaoling Zhang Xiuqing Guo Yasaman Saba Abbas Dehghan Adrie Seldenrijk Alanna C Morrison Anders Hamsten Bruce M Psaty Cornelia M van Duijn Deborah A Lawlor Dennis O Mook-Kanamori Donald W Bowden Helena Schmidt James F Wilson James G Wilson Jerome I Rotter Joanna M Wardlaw John Deanfield Julian Halcox Leo-Pekka Lyytikäinen Markus Loeffler Michele K Evans Stéphanie Debette Steve E Humphries Uwe Völker Vilmundur Gudnason Aroon D Hingorani Johan L M Björkegren Juan P Casas Christopher J O'Donnell

Nat Commun 2018 12 3;9(1):5141. Epub 2018 Dec 3.

Intramural Administration Management Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD, 20892, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-018-07340-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277418PMC
December 2018

Parameters of pulse wave velocity: determinants and reference values assessed in the population-based study LIFE-Adult.

Clin Res Cardiol 2018 Nov 15;107(11):1050-1061. Epub 2018 May 15.

Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Haertelstrasse 16-18, 04107, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00392-018-1278-3
Publisher Site
http://dx.doi.org/10.1007/s00392-018-1278-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208658PMC
November 2018

Genome-wide association study identifies inversion in the locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis.

Gut 2018 10 28;67(10):1855-1863. Epub 2017 Jul 28.

Department of Molecular and Cell Biology, Center for Exocrine Disorders, Boston University Henry M. Goldman School of Dental Medicine, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://gut.bmj.com/lookup/doi/10.1136/gutjnl-2017-314454
Publisher Site
http://dx.doi.org/10.1136/gutjnl-2017-314454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145291PMC
October 2018

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume.

Nat Commun 2018 09 26;9(1):3945. Epub 2018 Sep 26.

The University of Texas Health Science Center at Houston Institute of Molecular Medicine, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-018-06234-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158214PMC
September 2018

Increased Level of Interleukin 6 Associates With Increased 90-Day and 1-Year Mortality in Patients With End-Stage Liver Disease.

Clin Gastroenterol Hepatol 2018 05 14;16(5):730-737. Epub 2017 Sep 14.

Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cgh.2017.09.017DOI Listing
May 2018

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

Authors:
Gail Davies Max Lam Sarah E Harris Joey W Trampush Michelle Luciano W David Hill Saskia P Hagenaars Stuart J Ritchie Riccardo E Marioni Chloe Fawns-Ritchie David C M Liewald Judith A Okely Ari V Ahola-Olli Catriona L K Barnes Lars Bertram Joshua C Bis Katherine E Burdick Andrea Christoforou Pamela DeRosse Srdjan Djurovic Thomas Espeseth Stella Giakoumaki Sudheer Giddaluru Daniel E Gustavson Caroline Hayward Edith Hofer M Arfan Ikram Robert Karlsson Emma Knowles Jari Lahti Markus Leber Shuo Li Karen A Mather Ingrid Melle Derek Morris Christopher Oldmeadow Teemu Palviainen Antony Payton Raha Pazoki Katja Petrovic Chandra A Reynolds Muralidharan Sargurupremraj Markus Scholz Jennifer A Smith Albert V Smith Natalie Terzikhan Anbupalam Thalamuthu Stella Trompet Sven J van der Lee Erin B Ware B Gwen Windham Margaret J Wright Jingyun Yang Jin Yu David Ames Najaf Amin Philippe Amouyel Ole A Andreassen Nicola J Armstrong Amelia A Assareh John R Attia Deborah Attix Dimitrios Avramopoulos David A Bennett Anne C Böhmer Patricia A Boyle Henry Brodaty Harry Campbell Tyrone D Cannon Elizabeth T Cirulli Eliza Congdon Emily Drabant Conley Janie Corley Simon R Cox Anders M Dale Abbas Dehghan Danielle Dick Dwight Dickinson Johan G Eriksson Evangelos Evangelou Jessica D Faul Ian Ford Nelson A Freimer He Gao Ina Giegling Nathan A Gillespie Scott D Gordon Rebecca F Gottesman Michael E Griswold Vilmundur Gudnason Tamara B Harris Annette M Hartmann Alex Hatzimanolis Gerardo Heiss Elizabeth G Holliday Peter K Joshi Mika Kähönen Sharon L R Kardia Ida Karlsson Luca Kleineidam David S Knopman Nicole A Kochan Bettina Konte John B Kwok Stephanie Le Hellard Teresa Lee Terho Lehtimäki Shu-Chen Li Christina M Lill Tian Liu Marisa Koini Edythe London Will T Longstreth Oscar L Lopez Anu Loukola Tobias Luck Astri J Lundervold Anders Lundquist Leo-Pekka Lyytikäinen Nicholas G Martin Grant W Montgomery Alison D Murray Anna C Need Raymond Noordam Lars Nyberg William Ollier Goran Papenberg Alison Pattie Ozren Polasek Russell A Poldrack Bruce M Psaty Simone Reppermund Steffi G Riedel-Heller Richard J Rose Jerome I Rotter Panos Roussos Suvi P Rovio Yasaman Saba Fred W Sabb Perminder S Sachdev Claudia L Satizabal Matthias Schmid Rodney J Scott Matthew A Scult Jeannette Simino P Eline Slagboom Nikolaos Smyrnis Aïcha Soumaré Nikos C Stefanis David J Stott Richard E Straub Kjetil Sundet Adele M Taylor Kent D Taylor Ioanna Tzoulaki Christophe Tzourio André Uitterlinden Veronique Vitart Aristotle N Voineskos Jaakko Kaprio Michael Wagner Holger Wagner Leonie Weinhold K Hoyan Wen Elisabeth Widen Qiong Yang Wei Zhao Hieab H H Adams Dan E Arking Robert M Bilder Panos Bitsios Eric Boerwinkle Ornit Chiba-Falek Aiden Corvin Philip L De Jager Stéphanie Debette Gary Donohoe Paul Elliott Annette L Fitzpatrick Michael Gill David C Glahn Sara Hägg Narelle K Hansell Ahmad R Hariri M Kamran Ikram J Wouter Jukema Eero Vuoksimaa Matthew C Keller William S Kremen Lenore Launer Ulman Lindenberger Aarno Palotie Nancy L Pedersen Neil Pendleton David J Porteous Katri Räikkönen Olli T Raitakari Alfredo Ramirez Ivar Reinvang Igor Rudan Dan Rujescu Reinhold Schmidt Helena Schmidt Peter W Schofield Peter R Schofield John M Starr Vidar M Steen Julian N Trollor Steven T Turner Cornelia M Van Duijn Arno Villringer Daniel R Weinberger David R Weir James F Wilson Anil Malhotra Andrew M McIntosh Catharine R Gale Sudha Seshadri Thomas H Mosley Jan Bressler Todd Lencz Ian J Deary

Nat Commun 2018 05 29;9(1):2098. Epub 2018 May 29.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-018-04362-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974083PMC
May 2018

Relationship Between 12 Adipocytokines and Distinct Components of the Metabolic Syndrome.

J Clin Endocrinol Metab 2018 03;103(3):1015-1023

University of Leipzig, Department of Endocrinology and Nephrology, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2017-02085DOI Listing
March 2018

Model-based optimization of G-CSF treatment during cytotoxic chemotherapy.

J Cancer Res Clin Oncol 2018 Feb 4;144(2):343-358. Epub 2017 Nov 4.

Medical Faculty, Institute for Medical Informatics, Statistics and Epidemiology (IMISE), University of Leipzig, Haertelstraße 16-18, 04107, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00432-017-2540-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794835PMC
February 2018

Time to wake up: No impact of COMT Val158Met gene variation on circadian preferences, arousal regulation and sleep.

Chronobiol Int 2016 5;33(7):893-905. Epub 2016 May 5.

a LIFE - Leipzig Research Center for Civilization Diseases , University of Leipzig , Leipzig , Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/07420528.2016.1178275DOI Listing
January 2018

Sevoflurane and Isoflurane-Pharmacokinetics, Hemodynamic Stability and Cardio-protective Effects During Cardiopulmonary Bypass.

J Cardiothorac Vasc Anesth 2017 12 17;31(6):e85-e86. Epub 2016 Oct 17.

Department of Anesthesiology and Intensive Care Medicine, University Hospital Basel, Basel, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.jvca.2016.10.010DOI Listing
December 2017

Urine Biomarkers of Tubular Renal Cell Damage for the Prediction of Acute Kidney Injury After Cardiac Surgery-A Pilot Study.

J Cardiothorac Vasc Anesth 2017 Dec 16;31(6):2072-2079. Epub 2017 Apr 16.

Department of Anesthesiology, Surgical Intensive Care, Prehospital Emergency Medicine and Pain Therapy, University Hospital Basel, Basel, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.jvca.2017.04.024DOI Listing
December 2017

On the impact of relatedness on SNP association analysis.

BMC Genet 2017 Dec 6;18(1):104. Epub 2017 Dec 6.

Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Haertelstrasse 16-18, Leipzig, 04107, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12863-017-0571-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719591PMC
December 2017

Association between lipoprotein(a) level and type 2 diabetes: no evidence for a causal role of lipoprotein(a) and insulin.

Acta Diabetol 2017 Nov 2;54(11):1031-1038. Epub 2017 Sep 2.

Lipid Clinic at the Interdisciplinary Metabolism Center, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Augustenburger Platz 1, 13353, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00592-017-1036-4DOI Listing
November 2017

Growth and Final Height Among Children With Phenylketonuria.

Pediatrics 2017 Nov;140(5)

Center for Pediatric Research Leipzig, Department of Women and Child Health, Hospital for Children and Adolescents, University Hospitals,

View Article

Download full-text PDF

Source
http://pediatrics.aappublications.org/lookup/doi/10.1542/ped
Publisher Site
http://dx.doi.org/10.1542/peds.2017-0015DOI Listing
November 2017

Plasma Amino Acid Concentrations Predict Mortality in Patients with End-Stage Liver Disease.

PLoS One 2016 13;11(7):e0159205. Epub 2016 Jul 13.

Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0159205PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943589PMC
August 2017

Response to Sabour.

Pediatr Res 2017 08 21;82(2):177. Epub 2017 Jun 21.

Hospital for Children and Adolescents-Centre for Pediatric Research, Leipzig University, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/pr.2017.76DOI Listing
August 2017

FTO Obesity Risk Variants Are Linked to Adipocyte IRX3 Expression and BMI of Children - Relevance of FTO Variants to Defend Body Weight in Lean Children?

PLoS One 2016 25;11(8):e0161739. Epub 2016 Aug 25.

Center for Pediatric Research Leipzig (CPL), University Hospital for Children & Adolescents, University of Leipzig, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0161739PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999231PMC
July 2017

Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.

Authors:
Stephen Zewinger Marcus E Kleber Vinicius Tragante Raymond O McCubrey Amand F Schmidt Kenan Direk Ulrich Laufs Christian Werner Wolfgang Koenig Dietrich Rothenbacher Ute Mons Lutz P Breitling Herrmann Brenner Richard T Jennings Ioannis Petrakis Sarah Triem Mira Klug Alexandra Filips Stefan Blankenberg Christoph Waldeyer Christoph Sinning Renate B Schnabel Karl J Lackner Efthymia Vlachopoulou Ottar Nygård Gard Frodahl Tveitevåg Svingen Eva Ringdal Pedersen Grethe S Tell Juha Sinisalo Markku S Nieminen Reijo Laaksonen Stella Trompet Roelof A J Smit Naveed Sattar J Wouter Jukema Heinrich V Groesdonk Graciela Delgado Tatjana Stojakovic Anna P Pilbrow Vicky A Cameron A Mark Richards Robert N Doughty Yan Gong Rhonda Cooper-DeHoff Julie Johnson Markus Scholz Frank Beutner Joachim Thiery J Gustav Smith Ragnar O Vilmundarson Ruth McPherson Alexandre F R Stewart Sharon Cresci Petra A Lenzini John A Spertus Oliviero Olivieri Domenico Girelli Nicola I Martinelli Andreas Leiherer Christoph H Saely Heinz Drexel Axel Mündlein Peter S Braund Christopher P Nelson Nilesh J Samani Daniel Kofink Imo E Hoefer Gerard Pasterkamp Arshed A Quyyumi Yi-An Ko Jaana A Hartiala Hooman Allayee W H Wilson Tang Stanley L Hazen Niclas Eriksson Claes Held Emil Hagström Lars Wallentin Axel Åkerblom Agneta Siegbahn Igor Karp Christopher Labos Louise Pilote James C Engert James M Brophy George Thanassoulis Peter Bogaty Wojciech Szczeklik Marcin Kaczor Marek Sanak Salim S Virani Christie M Ballantyne Vei-Vei Lee Eric Boerwinkle Michael V Holmes Benjamin D Horne Aroon Hingorani Folkert W Asselbergs Riyaz S Patel Bernhard K Krämer Hubert Scharnagl Danilo Fliser Winfried März Thimoteus Speer

Lancet Diabetes Endocrinol 2017 07 26;5(7):534-543. Epub 2017 May 26.

Department of Internal Medicine IV, Saarland University Hospital, Homburg/Saar, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2213-8587(17)30096-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651679PMC
July 2017

Erratum to 'Independent Risk Factors for Fast-Track Failure Using a Predefined Fast-Track Protocol in Preselected Cardiac Surgery Patients' [Journal of Cardiothoracic and Vascular Anesthesia 29 (2015) 1461-1465].

J Cardiothorac Vasc Anesth 2017 Jun 21;31(3):1150. Epub 2016 Aug 21.

Department of Anesthesiology and Intensive Care Medicine, Heart Center, University Leipzig, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.jvca.2016.01.030DOI Listing
June 2017

Genome-wide meta-analysis identifies novel loci of plaque burden in carotid artery.

Atherosclerosis 2017 04 24;259:32-40. Epub 2017 Feb 24.

Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany; LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atherosclerosis.2017.02.018DOI Listing
April 2017

Cholesterol esterification in plasma as a biomarker for liver function and prediction of mortality.

BMC Gastroenterol 2017 Apr 20;17(1):57. Epub 2017 Apr 20.

Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Paul-List-Str. 13-15, 04103, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12876-017-0614-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397767PMC
April 2017

Body surface assessment with 3D laser-based anthropometry: reliability, validation, and improvement of empirical surface formulae.

Eur J Appl Physiol 2017 Feb 27;117(2):371-380. Epub 2017 Jan 27.

Leipzig Research Center for Civilization Diseases (LIFE), University of Leipzig, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00421-016-3525-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313586PMC
February 2017

Genome-wide association analysis of actigraphic sleep phenotypes in the LIFE Adult Study.

J Sleep Res 2016 12 29;25(6):690-701. Epub 2016 Apr 29.

LIFE-Leipzig Research Center for Civilization Diseases, Universität Leipzig, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jsr.12421DOI Listing
December 2016

Sevoflurane and Isoflurane-Pharmacokinetics, Hemodynamic Stability, and Cardioprotective Effects During Cardiopulmonary Bypass.

J Cardiothorac Vasc Anesth 2016 Dec 12;30(6):1494-1501. Epub 2016 Jul 12.

Department of Anesthesiology and Intensive Care Medicine, University Hospital Basel, Basel, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.jvca.2016.07.011DOI Listing
December 2016

Comparing performance of modern genotype imputation methods in different ethnicities.

Sci Rep 2016 10 4;6:34386. Epub 2016 Oct 4.

Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Haertelstrasse 16-18, 04107 Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep34386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048136PMC
October 2016

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis.

Sci Rep 2016 10 12;6:35278. Epub 2016 Oct 12.

Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep35278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059659PMC
October 2016

Genetic Factors of the Disease Course after Sepsis: A Genome-Wide Study for 28Day Mortality.

EBioMedicine 2016 Oct 15;12:239-246. Epub 2016 Sep 15.

Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany; Center for Clinical Studies, Jena University Hospital, Jena, Germany; Head of Paul-Martini-Clinical Sepsis Research Unit, Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ebiom.2016.08.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5078589PMC
October 2016

Brain Arousal Regulation in Carriers of Bipolar Disorder Risk Alleles.

Neuropsychobiology 2015 29;72(2):65-73. Epub 2015 Oct 29.

LIFE - Leipzig Research Centre for Civilization Diseases, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000437438DOI Listing
September 2016

Modeling combined chemo- and immunotherapy of high-grade non-Hodgkin lymphoma.

Leuk Lymphoma 2016 07 15;57(7):1697-708. Epub 2015 Dec 15.

a Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig , Leipzig , Germany ;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/10428194.2015.1110746DOI Listing
July 2016

PROGRESS - prospective observational study on hospitalized community acquired pneumonia.

BMC Pulm Med 2016 07 28;16(1):108. Epub 2016 Jul 28.

Department of Infectious Disease and Respiratory Medicine, Charité - University Medicine Berlin, Campus Virchowklinikum, Augustenburgerplatz 1, 13353, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12890-016-0255-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987996PMC
July 2016

Genetic Contribution of Variants near SORT1 and APOE on LDL Cholesterol Independent of Obesity in Children.

PLoS One 2015 16;10(9):e0138064. Epub 2015 Sep 16.

Center for Pediatric Research (CPL), University Hospital for Children and Adolescents Leipzig, Dept. of Women´s & Child Health, University of Leipzig, Leipzig, Germany; Integrated Research and Treatment Center Adiposity Diseases (IFB), Medical Faculty, University of Leipzig, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0138064PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573320PMC
May 2016

Reliability of 3D laser-based anthropometry and comparison with classical anthropometry.

Sci Rep 2016 05 26;6:26672. Epub 2016 May 26.

LIFE Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep26672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880916PMC
May 2016

Relationship Between Determinants of Arterial Stiffness Assessed by Diastolic and Suprasystolic Pulse Oscillometry: Comparison of Vicorder and Vascular Explorer.

Medicine (Baltimore) 2016 Mar;95(10):e2963

From the LIFE-Leipzig Research Center for Civilization Diseases (AT, FB, KW, ML, MS) and Institute for Medical Informatics, Statistics and Epidemiology (ML, MS), University of Leipzig and Department of Internal Medicine/Cardiology, Heart Center of the University Leipzig (AT, FB), Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000002963DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998878PMC
March 2016

Genetic variants of lipase activity in chronic pancreatitis.

Gut 2016 Jan 26;65(1):184-5. Epub 2015 Mar 26.

Division of Gastroenterology and Rheumatology, Department of Internal Medicine, Neurology and Dermatology, University of Leipzig, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/gutjnl-2015-309521DOI Listing
January 2016

Independent Risk Factors for Fast-Track Failure Using a Predefined Fast-Track Protocol in Preselected Cardiac Surgery Patients.

J Cardiothorac Vasc Anesth 2015 Dec 22;29(6):1461-5. Epub 2015 May 22.

Department of Anesthesiology and Intensive Care Medicine, Heart Center, University Leipzig, Leipzig, Germany.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10530770150050
Publisher Site
http://dx.doi.org/10.1053/j.jvca.2015.05.193DOI Listing
December 2015

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.

Authors:
Majid Nikpay Anuj Goel Hong-Hee Won Leanne M Hall Christina Willenborg Stavroula Kanoni Danish Saleheen Theodosios Kyriakou Christopher P Nelson Jemma C Hopewell Thomas R Webb Lingyao Zeng Abbas Dehghan Maris Alver Sebastian M Armasu Kirsi Auro Andrew Bjonnes Daniel I Chasman Shufeng Chen Ian Ford Nora Franceschini Christian Gieger Christopher Grace Stefan Gustafsson Jie Huang Shih-Jen Hwang Yun Kyoung Kim Marcus E Kleber King Wai Lau Xiangfeng Lu Yingchang Lu Leo-Pekka Lyytikäinen Evelin Mihailov Alanna C Morrison Natalia Pervjakova Liming Qu Lynda M Rose Elias Salfati Richa Saxena Markus Scholz Albert V Smith Emmi Tikkanen Andre Uitterlinden Xueli Yang Weihua Zhang Wei Zhao Mariza de Andrade Paul S de Vries Natalie R van Zuydam Sonia S Anand Lars Bertram Frank Beutner George Dedoussis Philippe Frossard Dominique Gauguier Alison H Goodall Omri Gottesman Marc Haber Bok-Ghee Han Jianfeng Huang Shapour Jalilzadeh Thorsten Kessler Inke R König Lars Lannfelt Wolfgang Lieb Lars Lind Cecilia M Lindgren Marja-Liisa Lokki Patrik K Magnusson Nadeem H Mallick Narinder Mehra Thomas Meitinger Fazal-Ur-Rehman Memon Andrew P Morris Markku S Nieminen Nancy L Pedersen Annette Peters Loukianos S Rallidis Asif Rasheed Maria Samuel Svati H Shah Juha Sinisalo Kathleen E Stirrups Stella Trompet Laiyuan Wang Khan S Zaman Diego Ardissino Eric Boerwinkle Ingrid B Borecki Erwin P Bottinger Julie E Buring John C Chambers Rory Collins L Adrienne Cupples John Danesh Ilja Demuth Roberto Elosua Stephen E Epstein Tõnu Esko Mary F Feitosa Oscar H Franco Maria Grazia Franzosi Christopher B Granger Dongfeng Gu Vilmundur Gudnason Alistair S Hall Anders Hamsten Tamara B Harris Stanley L Hazen Christian Hengstenberg Albert Hofman Erik Ingelsson Carlos Iribarren J Wouter Jukema Pekka J Karhunen Bong-Jo Kim Jaspal S Kooner Iftikhar J Kullo Terho Lehtimäki Ruth J F Loos Olle Melander Andres Metspalu Winfried März Colin N Palmer Markus Perola Thomas Quertermous Daniel J Rader Paul M Ridker Samuli Ripatti Robert Roberts Veikko Salomaa Dharambir K Sanghera Stephen M Schwartz Udo Seedorf Alexandre F Stewart David J Stott Joachim Thiery Pierre A Zalloua Christopher J O'Donnell Muredach P Reilly Themistocles L Assimes John R Thompson Jeanette Erdmann Robert Clarke Hugh Watkins Sekar Kathiresan Ruth McPherson Panos Deloukas Heribert Schunkert Nilesh J Samani Martin Farrall

Nat Genet 2015 Oct 7;47(10):1121-1130. Epub 2015 Sep 7.

Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589895PMC
October 2015

Integration of Genome-Wide SNP Data and Gene-Expression Profiles Reveals Six Novel Loci and Regulatory Mechanisms for Amino Acids and Acylcarnitines in Whole Blood.

PLoS Genet 2015 Sep 24;11(9):e1005510. Epub 2015 Sep 24.

LIFE Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig Germany; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1005510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581711PMC
September 2015

Impact of genetic similarity on imputation accuracy.

BMC Genet 2015 Jul 22;16:90. Epub 2015 Jul 22.

Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Haertelstrasse 16-18, 04107, Leipzig, Germany.

View Article

Download full-text PDF

Source
http://www.biomedcentral.com/1471-2156/16/90
Publisher Site
http://dx.doi.org/10.1186/s12863-015-0248-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509609PMC
July 2015

Associations between DNA methylation and schizophrenia-related intermediate phenotypes - a gene set enrichment analysis.

Prog Neuropsychopharmacol Biol Psychiatry 2015 Jun 15;59:31-39. Epub 2015 Jan 15.

Translational Developmental Neuroscience Section, Department of Child and Adolescent Psychiatry, Faculty of Medicine, TU Dresden, Dresden, Germany; Department of Psychiatry, Massachusetts General Hospital, Boston, MA USA; MGH/MIT/HMS Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pnpbp.2015.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346504PMC
June 2015