Markus Ritter, Dr.med.univ. - Paracelsus Medical University - Professor

Markus Ritter

Dr.med.univ.

Paracelsus Medical University

Professor

Salzburg | Austria

Main Specialties: Internal Medicine

Additional Specialties: Physiology and Pathophysiology

ORCID logohttps://orcid.org/0000-0001-7346-7750

Markus Ritter, Dr.med.univ. - Paracelsus Medical University - Professor

Markus Ritter

Dr.med.univ.

Introduction

Primary Affiliation: Paracelsus Medical University - Salzburg , Austria

Specialties:

Additional Specialties:

Research Interests:

Experience

Sep 2004
Paracelsus Medical University

Institute for Physiology and Pathophysiology

Publications

92Publications

650Reads

30Profile Views

Continuous, label-free, 96-well-based determination of cell migration using confluence measurement.

Cell Adh Migr 2019 Dec 8;13(1):76-82. Epub 2018 Oct 8.

a Institute of Physiology and Pathophysiology, Laboratory for Tumour Biology and Experimental Therapies (TREAT) , Paracelsus Medical University Salzburg , Salzburg , Austria.

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https://www.tandfonline.com/doi/full/10.1080/19336918.2018.1
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http://dx.doi.org/10.1080/19336918.2018.1526612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527382PMC
December 2019
1 Read
4.505 Impact Factor

Green exercise and mg-ca-SO thermal balneotherapy for the treatment of non-specific chronic low back pain: a randomized controlled clinical trial.

BMC Musculoskelet Disord 2019 May 17;20(1):221. Epub 2019 May 17.

Institute of Ecomedicine, Paracelsus Medical University, 5020, Salzburg, Austria.

Background: Non-specific chronic low back pain (nscLBP) has a high socio-economic relevance due to its high incidence, prevalence and associated costs. Therefore, it is essential to evaluate effective therapeutic strategies. This study examines the effects of moderate mountain exercise and spa therapy on orthopedic and psychophysiological parameters. Based on a three-armed randomized controlled trial, guided mountain hiking tours and balneotherapy in thermal water were compared to a control group.

Methods: Eighty patients with diagnosed nscLBP were separated into three groups: The two intervention groups GE (green exercise) and GEBT (green exercise and balneotherapy) undertook daily mountain hiking tours, whereas the GEBT group got an additional treatment with baths in Mg-Ca-SO thermal water. The third group (CO) received no intervention. GE and GEBT group were treated for 6 days; all groups were followed up for 120?days.

Results: Compared to GE and CO group, the GEBT treatment showed significant improvements of pain, some orthopedic parameters, health-related quality of life and mental well-being in patients with nscLBP.

Conclusions: The results of this study confirmed a benefit of mountain hiking combined with Mg-Ca-SO spa therapy as a multimodal treatment of patients with nscLBP. Further studies should focus on long-term-effects of this therapeutic approach.

Trial Registration: ISRCTN, ISRCTN99926592 . Registered 06. July 2018 - Retrospectively registered.

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https://bmcmusculoskeletdisord.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s12891-019-2582-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524239PMC
May 2019
9 Reads
1.898 Impact Factor

A Swelling-Activated Chloride Current in Microglial Cells is Suppressed by Epac and Facilitated by PKA - Impact on Phagocytosis.

Cell Physiol Biochem 2019 ;52(5):951-969

Department of Biosciences, University of Salzburg, Salzburg, Austria,

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http://dx.doi.org/10.33594/000000066DOI Listing
May 2019
11 Reads
2.875 Impact Factor

Glycine Induces Migration of Microglial BV-2 Cells via SNAT-Mediated Cell Swelling.

Cell Physiol Biochem 2018 25;50(4):1460-1473. Epub 2018 Oct 25.

Institute of Physiology and Pathophysiology, Paracelsus Medical University, Salzburg,

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https://www.karger.com/Article/FullText/494646
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http://dx.doi.org/10.1159/000494646DOI Listing
November 2018
28 Reads
2.880 Impact Factor

Miniaturization of the Clonogenic Assay Using Confluence Measurement.

Int J Mol Sci 2018 Mar 3;19(3). Epub 2018 Mar 3.

Laboratory for Tumour Biology and Experimental Therapies (TREAT), Institute of Physiology and Pathophysiology, Paracelsus Medical University Salzburg, Strubergasse 22, 5020 Salzburg, Austria.

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http://dx.doi.org/10.3390/ijms19030724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877585PMC
March 2018
9 Reads
2.862 Impact Factor

The histone methyltransferase G9a: a new therapeutic target in biliary tract cancer.

Hum Pathol 2018 02 11;72:117-126. Epub 2017 Nov 11.

Institute of Pathology, Cancer Cluster Salzburg, Paracelsus Medical University / Salzburger Landeskliniken (SALK), 5020 Salzburg, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2017.11.003DOI Listing
February 2018
31 Reads
2.770 Impact Factor

Update on the role and therapeutic potential of polycomb repressive complexes in (biliary tract) cancer.

Expert Opin Ther Targets 2018 01 20;22(1):1-3. Epub 2017 Nov 20.

b Department of Internal Medicine I, Paracelsus Medical University/Salzburger Landeskliniken and Laboratory for Tumour Biology and Experimental Therapies, Institute of Physiology and Pathophysiology , Paracelsus Medical University , Salzburg , Austria.

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http://dx.doi.org/10.1080/14728222.2018.1406923DOI Listing
January 2018
4 Reads
5.140 Impact Factor

The H+/K+ ATPase Inhibitor SCH-28080 Inhibits Insulin Secretion and Induces Cell Death in INS-1E Rat Insulinoma Cells.

Cell Physiol Biochem 2017 2;43(3):1037-1051. Epub 2017 Oct 2.

Institute of Physiology and Pathophysiology, Laboratory of Functional and Molecular Membrane Physiology, Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.1159/000481701DOI Listing
December 2017
21 Reads
2.880 Impact Factor

Biliary tract cancer stem cells - translational options and challenges.

World J Gastroenterol 2017 Apr;23(14):2470-2482

Christian Mayr, Tobias Kiesslich, Department of Internal Medicine I, Paracelsus Medical University, Salzburger Landeskliniken, 5020 Salzburg, Austria.

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http://dx.doi.org/10.3748/wjg.v23.i14.2470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5394510PMC
April 2017
23 Reads
2.370 Impact Factor

Quercetin Stimulates Insulin Secretion and Reduces the Viability of Rat INS-1 Beta-Cells.

Cell Physiol Biochem 2016 24;39(1):278-93. Epub 2016 Jun 24.

Institute of Physiology and Pathophysiology, Paracelsus Medical University, Salzburg, Austria.

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https://www.karger.com/Article/FullText/445623
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http://dx.doi.org/10.1159/000445623DOI Listing
February 2017
18 Reads
2.880 Impact Factor

Does waterfall aerosol influence mucosal immunity and chronic stress? A randomized controlled clinical trial.

J Physiol Anthropol 2017 Jan 13;36(1):10. Epub 2017 Jan 13.

Institute of Ecomedicine, Paracelsus Medical University, Strubergasse 22, 5020, Salzburg, Austria.

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http://dx.doi.org/10.1186/s40101-016-0117-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237191PMC
January 2017
6 Reads
1.164 Impact Factor

Relevance of MicroRNA200 Family and MicroRNA205 for Epithelial to Mesenchymal Transition and Clinical Outcome in Biliary Tract Cancer Patients.

Int J Mol Sci 2016 Dec 7;17(12). Epub 2016 Dec 7.

Laboratory for Tumour Biology and Experimental Therapies (TREAT), Institute of Physiology and Pathophysiology, Paracelsus Medical University, Salzburg 5020, Austria.

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http://dx.doi.org/10.3390/ijms17122053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187853PMC
December 2016
23 Reads
2.862 Impact Factor

The putative role of the non-gastric H⁺/K⁺-ATPase ATP12A (ATP1AL1) as anti-apoptotic ion transporter: effect of the H⁺/K⁺ ATPase inhibitor SCH28080 on butyrate-stimulated myelomonocytic HL-60 cells.

Cell Physiol Biochem 2014 9;34(5):1507-26. Epub 2014 Oct 9.

Institute of Physiology and Pathophysiology, Laboratory of Functional and Molecular Membrane Physiology, Paracelsus Medical University Salzburg, Salzburg, Austria.

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http://dx.doi.org/10.1159/000366355DOI Listing
August 2015
20 Reads
2.880 Impact Factor

Radon balneotherapy and physical activity for osteoporosis prevention: a randomized, placebo-controlled intervention study.

Radiat Environ Biophys 2015 Mar 2;54(1):123-136. Epub 2014 Oct 2.

Institute of Physiology and Pathophysiology, Paracelsus Medical University Salzburg, Strubergasse 21, 5020, Salzburg, Austria.

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http://dx.doi.org/10.1007/s00411-014-0568-zDOI Listing
March 2015
36 Reads
1.530 Impact Factor

Glycine modulates membrane potential, cell volume, and phagocytosis in murine microglia.

Amino Acids 2014 Aug 24;46(8):1907-17. Epub 2014 Apr 24.

Department of Cell Biology, University of Salzburg, Hellbrunnerstr. 34, 5020, Salzburg, Austria.

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http://dx.doi.org/10.1007/s00726-014-1745-8DOI Listing
August 2014
3 Reads
3.293 Impact Factor

Evidence for the formation of symmetric and asymmetric DLPC-DAPC lipid bilayer domains.

Cell Physiol Biochem 2013 4;32(1):46-52. Epub 2013 Jul 4.

Institute of Physiology and Pathophysiology, Paracelsus Medical University Salzburg, Salzburg, Austria.

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http://dx.doi.org/10.1159/000350122DOI Listing
March 2014
4 Reads
2.880 Impact Factor

Intrinsically active and pacemaker neurons in pluripotent stem cell-derived neuronal populations.

Stem Cell Reports 2014 Mar 20;2(3):323-36. Epub 2014 Feb 20.

Institute of Molecular Regenerative Medicine, Paracelsus Medical University, 5020 Salzburg, Austria, Austria ; Spinal Cord Injury and Tissue Regeneration Center Salzburg (SCI-TReCS), Salzburg, Paracelsus Medical University, 5020 Salzburg, Austria.

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http://dx.doi.org/10.1016/j.stemcr.2014.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964285PMC
March 2014
12 Reads

Extracts from Leonurus sibiricus L. increase insulin secretion and proliferation of rat INS-1E insulinoma cells.

J Ethnopharmacol 2013 Oct 24;150(1):85-94. Epub 2013 Aug 24.

Institute of Physiology and Pathophysiology, Paracelsus Medical University Salzburg, 5020 Salzburg, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2013.08.013DOI Listing
October 2013
2 Reads
3.000 Impact Factor

Chloride channel blockers suppress formation of engulfment pseudopodia in microglial cells.

Cell Physiol Biochem 2013 1;31(2-3):319-37. Epub 2013 Mar 1.

Department of Cell Biology, University of Salzburg, Salzburg, Austria.

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http://dx.doi.org/10.1159/000343370DOI Listing
September 2013
4 Reads
2.880 Impact Factor

Effects of ionized waterfall aerosol on pediatric allergic asthma.

J Asthma 2012 Oct 6;49(8):830-8. Epub 2012 Aug 6.

Institute of Physiology and Pathophysiology, Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.3109/02770903.2012.705408DOI Listing
October 2012
11 Reads
1.830 Impact Factor

Effect of the AMP-kinase modulators AICAR, metformin and compound C on insulin secretion of INS-1E rat insulinoma cells under standard cell culture conditions.

Cell Physiol Biochem 2012 1;29(1-2):75-86. Epub 2012 Mar 1.

Institute of Physiology and Pathophysiology, Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.1159/000337589DOI Listing
July 2012
35 Reads
2.880 Impact Factor

Expression of the non-gastric H+/K+ ATPase ATP12A in normal and pathological human prostate tissue.

Cell Physiol Biochem 2011 16;28(6):1287-94. Epub 2011 Dec 16.

Institute of Physiology and Pathophysiology, Paracelsus Medical University Salzburg, Salzburg, Austria.

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http://dx.doi.org/10.1159/000335860DOI Listing
April 2012
6 Reads
2.880 Impact Factor

Vacuolar-type H+-ATPase-mediated proton transport in the rat parietal cell.

Pflugers Arch 2012 Mar 17;463(3):419-27. Epub 2011 Nov 17.

Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1007/s00424-011-1060-0DOI Listing
March 2012
2 Reads
4.101 Impact Factor

Hypoxia inhibits colonic ion transport via activation of AMP kinase.

Ann Surg 2011 Dec;254(6):957-63

University College Dublin and St Vincent's University Hospital, Elm Park, Dublin, Ireland.

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http://dx.doi.org/10.1097/SLA.0b013e31821d477fDOI Listing
December 2011
3 Reads
8.330 Impact Factor

K16 is a further new candidate for homotypic intermediate filament protein interactions.

Exp Dermatol 2010 Aug;19(8):e241-50

Division of Molecular Dermatology, Department of Dermatology, Paracelsus Medical University Salzburg, Salzburg, Austria.

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http://dx.doi.org/10.1111/j.1600-0625.2010.01071.xDOI Listing
August 2010
5 Reads
3.762 Impact Factor

Ion channels and cell volume in regulation of cell proliferation and apoptotic cell death.

Contrib Nephrol 2006 ;152:142-160

Department of Physiology, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1159/000096321DOI Listing
August 2010
1 Read
1.534 Impact Factor

Ethanol inhibits gastric acid secretion in rats through increased AMP-kinase activity.

Cell Physiol Biochem 2010 12;25(2-3):195-202. Epub 2010 Jan 12.

Department of Surgery, Yale University, School of Medicine, New Haven, CT 06511, USA.

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http://dx.doi.org/10.1159/000276553DOI Listing
April 2010
3 Reads
2.880 Impact Factor

The phytostilbene resveratrol induces apoptosis in INS-1E rat insulinoma cells.

Cell Physiol Biochem 2009 6;23(4-6):245-54. Epub 2009 May 6.

Institute of Physiology and Pathophysiology, Paracelsus Medical University Salzburg, Salzburg, Austria.

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http://dx.doi.org/10.1159/000218171DOI Listing
August 2009
8 Reads
2.880 Impact Factor

Quaternary structure assessment of ICln by fluorescence resonance energy transfer (FRET) in vivo.

Cell Physiol Biochem 2009 6;23(4-6):397-406. Epub 2009 May 6.

Institute of Physiology and Pathophysiology, Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.1159/000218186DOI Listing
August 2009
10 Reads
2.880 Impact Factor

LSm4 associates with the plasma membrane and acts as a co-factor in cell volume regulation.

Cell Physiol Biochem 2008 9;22(5-6):579-90. Epub 2008 Dec 9.

Department of Physiology and Medical Physics, Division of Physiology, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1159/000185542DOI Listing
February 2009
3 Reads
2.880 Impact Factor

Resveratrol inhibits electrical activity and insulin release from insulinoma cells by block of voltage-gated Ca+ channels and swelling-dependent Cl- currents.

Cell Physiol Biochem 2008 9;22(5-6):567-78. Epub 2008 Dec 9.

Institute of Physiology and Pathophysiology, Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.1159/000185541DOI Listing
February 2009
12 Reads
2.880 Impact Factor

Resveratrol inhibits electrical activity and insulin release from insulinoma cells by block of voltage-gated Ca+ channels and swelling-dependent Cl- currents.

Cell Physiol Biochem 2008 9;22(5-6):567-78. Epub 2008 Dec 9.

Institute of Physiology and Pathophysiology, Paracelsus Medical University, Salzburg, Austria.

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http://dx.doi.org/10.1159/000185541DOI Listing
February 2009
12 Reads
2.880 Impact Factor

Further characterization of the nematode IClnN2 protein reconstituted in lipid bilayers.

Adv Exp Med Biol 2004 ;559:245-51

Institute of Physiology, University of Innsbruck, Fritz-Pregl Strasse 3, A-6020 Innsbruck, Austria.

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http://dx.doi.org/10.1007/0-387-23752-6_23DOI Listing
September 2008

Probing of the ICln channel pore by cysteine mutagenesis and cadmium-block.

Adv Exp Med Biol 2004 ;559:99-108

Department of Physiology, University of Innsbruck, Fritz-Pregl-Str. 3, A-6020 Innsbruck, Austria.

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http://dx.doi.org/10.1007/0-387-23752-6_9DOI Listing
September 2008

Fixation, mounting and sealing with nail polish of cell specimens lead to incorrect FRET measurements using acceptor photobleaching.

Cell Physiol Biochem 2008 24;21(5-6):489-98. Epub 2008 Apr 24.

CIMAINA, Salzburg, Austria.

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http://dx.doi.org/10.1159/000129642DOI Listing
August 2008
18 Reads
2.880 Impact Factor

Differential expression of GHRH receptor and its splice variant 1 in human normal and malignant mucosa of the oesophagus and colon.

Int J Oncol 2008 Jul;33(1):137-43

Department of Internal Medicine, General Hospital Oberndorf, Teaching Hospital of the Paracelsus Private Medical University of Salzburg, 5110 Oberndorf, Austria.

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July 2008
32 Reads
3.025 Impact Factor

Cell volume regulatory ion channels in cell proliferation and cell death.

Methods Enzymol 2007 ;428:209-25

Department of Physiology, University of Tübingen, Germany.

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http://dx.doi.org/10.1016/S0076-6879(07)28011-5DOI Listing
November 2007
2 Reads
2.090 Impact Factor

Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1.

Nat Med 2007 Apr 11;13(4):448-54. Epub 2007 Feb 11.

Department of General Internal Medicine, Clinical Immunology and Infectious Diseases, Innsbruck Medical University, Anichstr. 35, A-6020 Innsbruck, Austria.

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http://dx.doi.org/10.1038/nm1542DOI Listing
April 2007
12 Reads
27.363 Impact Factor

The ICln interactome.

Acta Physiol (Oxf) 2006 May-Jun;187(1-2):43-9

Department of Physiology and Medical Physics, Innsbruck Medical University, Innsbruck, Austria.

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http://dx.doi.org/10.1111/j.1748-1716.2006.01549.xDOI Listing
January 2007
4.382 Impact Factor

Fast fluorometric method for measuring pendrin (SLC26A4) Cl-/I- transport activity.

Cell Physiol Biochem 2006 15;18(1-3):67-74. Epub 2006 Aug 15.

Department of Biomolecular Sciences and Biotechnology, Universitá degli Studi di Milano.

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http://dx.doi.org/10.1159/000095164DOI Listing
September 2006
17 Reads
2.880 Impact Factor

Glucose induces anion conductance and cytosol-to-membrane transposition of ICln in INS-1E rat insulinoma cells.

Cell Physiol Biochem 2006 14;18(1-3):21-34. Epub 2006 Aug 14.

Institute of Physiology and Pathophysiology, Paracelsus Private Medical University, Salzburg.

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http://dx.doi.org/10.1159/000095131DOI Listing
September 2006
3 Reads
2.880 Impact Factor

ICln159 folds into a pleckstrin homology domain-like structure. Interaction with kinases and the splicing factor LSm4.

J Biol Chem 2005 Sep 19;280(35):31276-82. Epub 2005 May 19.

Department of Physiology and Medical Physics, Innsbruck Medical University, Fritz-Pregl Strasse 3, A-6020 Innsbruck, Austria.

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http://dx.doi.org/10.1074/jbc.M500541200DOI Listing
September 2005
19 Reads
4.573 Impact Factor

Thiazide-sensitive NaCl-cotransporter in the intestine: possible role of hydrochlorothiazide in the intestinal Ca2+ uptake.

J Biol Chem 2005 May 21;280(20):19902-10. Epub 2005 Mar 21.

Department of Biomolecular Sciences and Biotechnology, Università degli Studi di Milano, Italy.

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http://dx.doi.org/10.1074/jbc.M411961200DOI Listing
May 2005
12 Reads
4.573 Impact Factor

Membrane thickness changes ion-selectivity of channel-proteins.

Cell Physiol Biochem 2004 ;14(4-6):231-40

Department of Biomolecular Sciences and Biotechnology, Università degli Studi di Milano, Italy.

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http://dx.doi.org/10.1159/000080332DOI Listing
February 2005
6 Reads
2.880 Impact Factor

Cell swelling stimulates cytosol to membrane transposition of ICln.

J Biol Chem 2003 Dec 11;278(50):50163-74. Epub 2003 Sep 11.

Department of Physiology, University of Innsbruck, Fritz-Pregl-Strasse 3, A-6020 Innsbruck, Austria.

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http://dx.doi.org/10.1074/jbc.M300374200DOI Listing
December 2003
15 Reads
4.573 Impact Factor

Simvastatin inhibits malignant transformation following expression of the Ha-ras oncogene in NIH 3T3 fibroblasts.

Cell Physiol Biochem 2002 ;12(1):19-30

Department of Physiology, University of Innsbruck, Fritz-Pregl-Strasse 3, A-6010 Innsbruck, Austria.

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http://dx.doi.org/10.1159/000047823DOI Listing
July 2002
14 Reads
2.880 Impact Factor

Molecular and functional aspects of anionic channels activated during regulatory volume decrease in mammalian cells.

Pflugers Arch 2002 May 8;444(1-2):1-25. Epub 2002 Mar 8.

Institut für Physiologie, Universität Innsbruck, Fritz Pregl-Strasse 3, Austria.

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http://dx.doi.org/10.1007/s00424-002-0805-1DOI Listing
May 2002
4.101 Impact Factor

ICln channels reconstituted in heart-lipid bilayer are selective to chloride.

Pflugers Arch 2002 Mar 23;443(5-6):748-53. Epub 2002 Jan 23.

Institute of Physiology, University of Innsbuck, Austria.

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http://dx.doi.org/10.1007/s00424-001-0772-yDOI Listing
March 2002
18 Reads
4.101 Impact Factor

ICln ion channel splice variants in Caenorhabditis elegans: voltage dependence and interaction with an operon partner protein.

J Biol Chem 2002 Feb 12;277(6):4435-45. Epub 2001 Nov 12.

Department of Physiology, University of Innsbruck, Fritz-Pregl-Strasse 3, A-6020 Innsbruck, Austria.

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http://dx.doi.org/10.1074/jbc.M107372200DOI Listing
February 2002
2 Reads
4.573 Impact Factor

Determination of protein-protein interactions of ICIn by the yeast two-hybrid system.

Cell Physiol Biochem 2001 ;11(1):55-60

Department of Physiology, Institute for Medical Biology and Human Genetics, University of Innsbruck, Austria.

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http://dx.doi.org/10.1159/000047792DOI Listing
August 2001
2.880 Impact Factor

Na(+)/H(+)exchangers: linking osmotic dysequilibrium to modified cell function.

Cell Physiol Biochem 2001 ;11(1):1-18

Department of Physiology, University of Innsbruck, Austria.

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http://dx.doi.org/10.1159/000047787DOI Listing
August 2001
2.880 Impact Factor

Structure and function of the ion channel ICln.

Cell Physiol Biochem 2000 ;10(5-6):329-34

Department of Physiology, University of Innsbruck, Fritz-Pregl-Str. 3, A-6020 Innsbruck, Austria.

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http://dx.doi.org/10.1159/000016374DOI Listing
March 2001
2.880 Impact Factor

Functional reconstitution of ICln in lipid bilayers.

Pflugers Arch 2000 May;440(1):100-15

Department of Physiology, University of Innsbruck, Austria.

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http://dx.doi.org/10.1007/s004240000250DOI Listing
May 2000
4.101 Impact Factor

The promoter for constitutive expression of the human ICln gene CLNS1A.

J Biol Chem 2000 May;275(21):15613-20

Department of Physiology, University of Innsbruck, Fritz-Pregl Strasse 3, A-6020 Innsbruck, Austria.

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http://dx.doi.org/10.1074/jbc.275.21.15613DOI Listing
May 2000
4.573 Impact Factor

The gastric H,K-ATPase blocker lansoprazole is an inhibitor of chloride channels.

Br J Pharmacol 2000 Feb;129(3):598-604

Department of Physiology, University of Innsbruck, Austria.

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http://dx.doi.org/10.1038/sj.bjp.0703070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1571856PMC
February 2000
4.842 Impact Factor

ICln, an ion channel-forming protein associated with cell volume regulation.

Exp Physiol 1999 Nov;84(6):1023-31

Department of Physiology, University of Innsbruck, Fritz-Pregl-Strasse 3, A-6020 Innsbruck, Austria.

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November 1999
2.670 Impact Factor

Effects of bradykinin on NIH 3T3 fibroblasts pretreated with lithium. Mimicking events of Ha-ras oncogene expression.

Biochim Biophys Acta 1997 Aug;1358(1):23-30

Department of Internal Medicine, University of Innsbruck, Austria.

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http://dx.doi.org/10.1016/s0167-4889(97)00046-3DOI Listing
August 1997
3 Reads

Activation of Na+/H(+)-exchanger by transforming Ha-ras requires stimulated cellular calcium influx and is associated with rearrangement of the actin cytoskeleton.

Eur J Cell Biol 1997 Mar;72(3):222-8

Hospital for Internal Medicine, University of Innsbruck, Innsbruck/Austria.

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March 1997
3 Reads
3.830 Impact Factor

Calcium entry stimulated by swelling of Madin-Darby canine kidney cells.

Nephron 1996 ;74(1):150-7

Hospital for Internal Medicine, University of Innsbruck, Austria.

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http://dx.doi.org/10.1159/000189295DOI Listing
January 1997

Modification of Cellular Ion Transport by the Ha-ras Oncogene: Steps towards Malignant Transformation

Cell Physiol Biochem 1996;6:245–270

Cellular Physiology and Biochemistry

Expression of the transforming Ha-ras oncogene in NIH 3T3 fibroblasts (+ras cells) results in growth-factor-independent proliferation, breakdown of actin stress fiber network and increase in intracellular pH and cell volume due to activation of the Na+/H+ exchanger and Na+, K+, 2C1- cotransport. +ras cells respond to mitogens like serum or bradykinin with sustained oscillations of the cell membrane potential due to stimulated calcium entry which triggers pulsatile release of calcium from internal stores and subsequent activation of calcium-sensitive K+ channels. Calcium antagonists like bepridil or nifedipine inhibit cellular calcium entry and oscillations of the intracellular calcium concentration, protect +ras cells against actin stress fiber depolymerization, block activation of the Na+/H+ exchanger and inhibit cell proliferation. Inhibition of the Na+/H+ exchanger inhibits the increase in the intracellular pH and cell proliferation but does not alter cytoskeletal rearrangement, calcium entry or oscillations of intracellular calcium. In cells not expressing the oncogene (-ras cells), bradykinin causes a single transient hyperpolarization, is without effect on cytoarchitecture and leads to cell shrinkage unless actin filament disruption is induced by cytochalasin D or pretreatment of the cells with LiCl. Apparently the oscillations of intracellular calcium are required for depolymerization of the actin filaments and for activation of the Na+/H+ exchanger. Thus the alterations of ion transport are prerequisites for growth-factor-independent proliferation of Ha-ras-oncogene-expressing cells.

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June 1996
114 Reads

Antisense oligonucleotides suppress cell-volume-induced activation of chloride channels.

Pflugers Arch 1995 Aug;430(4):464-70

Department of Physiology, University of Innsbruck, Austria.

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http://dx.doi.org/10.1007/bf00373882DOI Listing
August 1995
4.101 Impact Factor

Structure-function relation of a cloned epithelial chloride channel.

Ren Physiol Biochem 1994 May-Aug;17(3-4):148-52

Department of Physiology, University of Innsbruck, Austria.

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August 1994

The biological significance of cell volume.

Ren Physiol Biochem 1993 Jan-Apr;16(1-2):48-65

Institute for Physiology, University of Innsbruck, Austria.

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June 1993
1 Read

Cell shrinkage stimulates bradykinin-induced cell membrane potential oscillations in NIH 3T3 fibroblasts expressing the ras-oncogene.

Pflugers Arch 1993 May;423(3-4):221-4

Physiologisches Institut, Universität Innsbruck, Austria.

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http://dx.doi.org/10.1007/bf00374398DOI Listing
May 1993
4.101 Impact Factor

Cell membrane potential oscillations induced by kinins in fibroblasts expressing the Ha-ras oncogene.

Agents Actions Suppl 1992 ;38 ( Pt 2):73-80

Institute for Physiology, University of Innsbruck, Austria.

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January 1993
2 Reads

Effects of inhibitors and ion substitutions on oscillations of cell membrane potential in cells expressing the RAS oncogene.

Pflugers Arch 1992 Aug;421(5):416-24

Institute for Physiology, University of Innsbruck, Austria.

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http://dx.doi.org/10.1007/bf00370251DOI Listing
August 1992
4.101 Impact Factor

Effects of bradykinin on cell volume and intracellular pH in NIH 3T3 fibroblasts expressing the ras oncogene.

FEBS Lett 1992 Aug;307(3):367-70

Institut für Physiologie, Universität Innsbruck, Austria.

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http://dx.doi.org/10.1016/0014-5793(92)80714-rDOI Listing
August 1992
5 Reads
3.170 Impact Factor

Altered cell volume regulation in ras oncogene expressing NIH fibroblasts.

Pflugers Arch 1992 Apr;420(5-6):424-7

Institut für Physiologie, Universität Innsbruck, Austria.

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http://dx.doi.org/10.1007/bf00374615DOI Listing
April 1992
3 Reads
4.101 Impact Factor

Effect of bradykinin, ATP and adrenaline on cell membrane resistances of Madin-Darby canine kidney cells.

Authors:
M Ritter F Lang

J Physiol 1991 Nov;443:45-54

Institute for Physiology, University of Innsbruck, Austria.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1179829PMC
http://dx.doi.org/10.1113/jphysiol.1991.sp018821DOI Listing
November 1991
5.040 Impact Factor

Inhibition of ion conductances by osmotic shrinkage of Madin-Darby canine kidney cells.

Am J Physiol 1991 Oct;261(4 Pt 1):C602-7

Institute for Physiology, University of Innsbruck, Austria.

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http://dx.doi.org/10.1152/ajpcell.1991.261.4.C602DOI Listing
October 1991

Hepatorenal reflex regulating kidney function.

Hepatology 1991 Oct;14(4 Pt 1):590-4

Institute for Physiology, University of Innsbruck, Austria.

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http://dx.doi.org/10.1016/0270-9139(91)90043-uDOI Listing
October 1991
11.055 Impact Factor

Influence of mercury ions on electrical properties of rat proximal and distal renal tubules.

Nephron 1991 ;58(2):229-32

Institute of Physiology, University of Innsbruck, Austria.

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http://dx.doi.org/10.1159/000186420DOI Listing
September 1991

Regulation of potassium conductance by prostaglandins in cultured renal epitheloid (Madin-Darby canine kidney) cells.

Pflugers Arch 1991 Jun;418(5):431-6

Institute for Physiology, University of Innsbruck, Austria.

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http://dx.doi.org/10.1007/bf00497769DOI Listing
June 1991
4.101 Impact Factor

Progesterone inhibits K conductance in plasma membrane of cultured renal epitheloid MDCK cells.

Am J Physiol 1991 May;260(5 Pt 1):E743-50

Institute for Physiology, University of Innsbruck, Austria.

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http://dx.doi.org/10.1152/ajpendo.1991.260.5.E743DOI Listing
May 1991
2 Reads

Cellular mechanisms of bradykinin-induced hyperpolarization in renal epitheloid MDCK-cells.

Biochim Biophys Acta 1991 Apr;1073(3):600-8

Institute for Physiology, University of Innsbruck, Austria.

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http://dx.doi.org/10.1016/0304-4165(91)90236-aDOI Listing
April 1991

Further characterization of volume regulatory decrease in cultured renal epitheloid (MDCK) cells.

Pflugers Arch 1991 Mar;418(1-2):35-9

Institute for Physiology, University of Innsbruck, Austria.

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http://dx.doi.org/10.1007/bf00370449DOI Listing
March 1991
4.101 Impact Factor

Activation of cell membrane potassium conductance by mercury in cultured renal epithelioid (MDCK) cells.

J Cell Physiol 1991 Jan;146(1):25-33

Institute for Physiology, University of Innsbruck, Austria.

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http://dx.doi.org/10.1002/jcp.1041460105DOI Listing
January 1991
1 Read
3.840 Impact Factor

Determination of cell membrane resistance in cultured renal epithelioid (MDCK) cells: effects of cadmium and mercury ions.

Pflugers Arch 1990 Sep;417(1):29-36

Institute for Physiology, University of Innsbruck, Austria.

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http://dx.doi.org/10.1007/bf00370765DOI Listing
September 1990
1 Read
4.101 Impact Factor

Ion channels in Madin-Darby canine kidney cells.

Ren Physiol Biochem 1990 Jan-Apr;13(1-2):82-93

Institute for Physiology University of Innsbruck, Austria.

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April 1990

A simple method for multiple fluid exchange.

Authors:
M Ritter F Lang

Pflugers Arch 1989 Nov;415(2):241-3

Institute for Physiology, University of Innsbruck, Austria.

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http://dx.doi.org/10.1007/bf00370599DOI Listing
November 1989
1 Read
4.101 Impact Factor

Anthracene-9-carboxylic acid inhibits renal chloride reabsorption.

Pflugers Arch 1983 Jul;398(2):172-4

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http://dx.doi.org/10.1007/bf00581068DOI Listing
July 1983
4.101 Impact Factor

Top co-authors

Martin Jakab
Martin Jakab

Institute of Physiology and Pathophysiology

31
F Lang
F Lang

University of Tübingen

29
Johannes Furst
Johannes Furst

University of Innsbruck

20
Markus Paulmichl
Markus Paulmichl

Paracelsus Medical University

20
M Paulmichl
M Paulmichl

University of Innsbruck

19
J Furst
J Furst

California School of Professional Psychology

10
Claudia Bazzini
Claudia Bazzini

Università degli Studi di Milano

10
Tobias Kiesslich
Tobias Kiesslich

Paracelsus Medical University/Salzburger Landeskliniken (SALK)

10
Marlena Beyreis
Marlena Beyreis

University of Salzburg

9