Markus Gerhard

Markus Gerhard

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Markus Gerhard

Markus Gerhard

Publications by authors named "Markus Gerhard"

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Exploits the NLRC4 Inflammasome to Dampen Host Defenses.

J Immunol 2019 Oct 11;203(8):2183-2193. Epub 2019 Sep 11.

Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Fakultät für Medizin, Technische Universität München, 81675 Munich, Germany; and

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1900351
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http://dx.doi.org/10.4049/jimmunol.1900351DOI Listing
October 2019

Quantitation of norovirus-specific IgG before and after infection in immunocompromised patients.

Braz J Microbiol 2019 Oct 26. Epub 2019 Oct 26.

Institute of Virology, Technische Universität und Helmholtz Zentrum München, Munich, Germany.

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http://dx.doi.org/10.1007/s42770-019-00176-1DOI Listing
October 2019

Association Between Gut Microbiota and -Related Gastric Lesions in a High-Risk Population of Gastric Cancer.

Front Cell Infect Microbiol 2018 19;8:202. Epub 2018 Jun 19.

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Cancer Epidemiology, Peking University Cancer Hospital and Institute, Beijing, China.

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http://dx.doi.org/10.3389/fcimb.2018.00202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018392PMC
July 2019

Concomitant Infection of S. mansoni and H. pylori Promotes Promiscuity of Antigen-Experienced Cells and Primes the Liver for a Lower Fibrotic Response.

Cell Rep 2019 Jul;28(1):231-244.e5

Institute for Medical Microbiology, Immunology and Hygiene, Technical University of Munich, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.05.108DOI Listing
July 2019

The Helicobacter pylori Type IV Secretion System Encoded by the cag Pathogenicity Island: Architecture, Function, and Signaling.

Curr Top Microbiol Immunol 2017;413:187-220

Institute of Experimental Internal Medicine, Otto von Guericke University, 39120, Magdeburg, Germany.

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http://dx.doi.org/10.1007/978-3-319-75241-9_8DOI Listing
May 2019

Mutated Aggravates -Induced Gastric Pathology.

Cancers (Basel) 2019 Mar 16;11(3). Epub 2019 Mar 16.

Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, 81675 Munich, Germany.

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http://dx.doi.org/10.3390/cancers11030372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468876PMC
March 2019

The HopQ outermembrane protein inhibits immune cell activities.

Oncoimmunology 2019 29;8(4):e1553487. Epub 2019 Jan 29.

The Institute of Dental Sciences, The Hebrew University-Hadassah School of Dental Medicine, Jerusalem, Israel.

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http://dx.doi.org/10.1080/2162402X.2018.1553487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422397PMC
January 2019

Evidence suggests that germline mutations are a rare cause of serrated polyposis.

Gut 2018 12 12;67(12):2230-2232. Epub 2018 Jan 12.

Hereditary Cancer Program, Catalan Institute of Oncology, IDIBELL, Hospitalet de Llobregat, Barcelona, Spain.

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http://gut.bmj.com/lookup/doi/10.1136/gutjnl-2017-315733
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http://dx.doi.org/10.1136/gutjnl-2017-315733DOI Listing
December 2018

Helicobacter pylori γ-glutamyl transferase contributes to colonization and differential recruitment of T cells during persistence.

Sci Rep 2017 10 20;7(1):13636. Epub 2017 Oct 20.

Institut für medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, 81675, Munich, Germany.

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http://dx.doi.org/10.1038/s41598-017-14028-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651840PMC
October 2017

Lymphotoxin β receptor signalling executes -driven gastric inflammation in a T4SS-dependent manner.

Gut 2017 08 13;66(8):1369-1381. Epub 2016 Apr 13.

Institut für Virologie, Technische Universität München, Helmholtz Zentrum München, Neuherberg, Germany.

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http://dx.doi.org/10.1136/gutjnl-2015-310783DOI Listing
August 2017

Immune Evasion Strategies and Persistence of Helicobacter pylori.

Curr Top Microbiol Immunol 2017;400:53-71

Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1007/978-3-319-50520-6_3DOI Listing
June 2017

Cut-off optimization for C-urea breath test in a community-based trial by mathematic, histology and serology approach.

Sci Rep 2017 05 18;7(1):2072. Epub 2017 May 18.

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Cancer Epidemiology, Peking University Cancer Hospital & Institute, 52 Fu-cheng Road, Hai-dian District, Beijing, 100142, China.

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http://www.nature.com/articles/s41598-017-02180-7
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http://dx.doi.org/10.1038/s41598-017-02180-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5437005PMC
May 2017

Inflammation, immunity, and vaccines for Helicobacter pylori infection.

Helicobacter 2016 Sep;21 Suppl 1:26-9

ImevaX GmbH, Munich, Germany.

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http://doi.wiley.com/10.1111/hel.12336
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http://dx.doi.org/10.1111/hel.12336DOI Listing
September 2016

Helicobacter pylori γ-Glutamyltranspeptidase Induces Tolerogenic Human Dendritic Cells by Activation of Glutamate Receptors.

J Immunol 2016 05 18;196(10):4246-52. Epub 2016 Apr 18.

Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, 81675 Munich, Germany; and

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1501062
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http://dx.doi.org/10.4049/jimmunol.1501062DOI Listing
May 2016

T cell-specific inactivation of mouse CD2 by CRISPR/Cas9.

Sci Rep 2016 Feb 23;6:21377. Epub 2016 Feb 23.

Institute for Medical Microbiology, Immunology and Hygiene, Technische Universität München, Germany.

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http://dx.doi.org/10.1038/srep21377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763270PMC
February 2016

High Frequency of vacA s1m2 Genotypes Among Helicobacter pylori Isolates From Patients With Gastroduodenal Disorders in Kermanshah, Iran.

Jundishapur J Microbiol 2015 Nov 22;8(11):e25425. Epub 2015 Nov 22.

Department of Microbiology, Faculty of Medicine, Kermanshah University of Medical Sciences, Kermanshah, IR Iran.

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http://dx.doi.org/10.5812/jjm.25425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740511PMC
November 2015

Diagnosis of : Changes towards the Future.

Diseases 2015 Jun 29;3(3):122-135. Epub 2015 Jun 29.

Institute of Medical Microbiology, Immunology and Hygiene, TU-Munich, Troger Str.30, 81675 Munich, Germany.

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http://dx.doi.org/10.3390/diseases3030122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548244PMC
June 2015

Involvement of Toll-like receptors on Helicobacter pylori-induced immunity.

PLoS One 2014 25;9(8):e104804. Epub 2014 Aug 25.

Lehrstuhl für Innere Medizin 1, Universität Witten/Herdecke, Wuppertal, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104804PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143222PMC
May 2015

Helicobacter pylori γ-glutamyltranspeptidase impairs T-lymphocyte function by compromising metabolic adaption through inhibition of cMyc and IRF4 expression.

Cell Microbiol 2015 Jan 30;17(1):51-61. Epub 2014 Aug 30.

Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, 81675, Munich, Germany.

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http://dx.doi.org/10.1111/cmi.12335DOI Listing
January 2015

H. pylori virulence factors: influence on immune system and pathology.

Mediators Inflamm 2014 21;2014:426309. Epub 2014 Jan 21.

Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, 81675 Munich, Germany.

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http://dx.doi.org/10.1155/2014/426309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918698PMC
October 2014

Helicobacter pylori-induced IL-1β secretion in innate immune cells is regulated by the NLRP3 inflammasome and requires the cag pathogenicity island.

J Immunol 2014 Oct 29;193(7):3566-76. Epub 2014 Aug 29.

Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, 81675 Munich, Germany; German Centre for Infection Research, Partner Site Munich, 81675 Munich, Germany

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http://dx.doi.org/10.4049/jimmunol.1400362DOI Listing
October 2014

Helicobacter pylori vaccination: is there a path to protection?

World J Gastroenterol 2014 Sep;20(34):11939-49

Florian Anderl, Markus Gerhard, Institute for Medical Microbiology, Immunology and Hygiene, Technische Universität München, Munich 81675, Germany.

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http://dx.doi.org/10.3748/wjg.v20.i34.11939DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161780PMC
September 2014

Helicobacter pylori antibody responses and evolution of precancerous gastric lesions in a Chinese population.

Int J Cancer 2014 May 7;134(9):2118-25. Epub 2013 Nov 7.

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Cancer Epidemiology, Peking University Cancer Hospital & Institute, Beijing, China.

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http://dx.doi.org/10.1002/ijc.28560DOI Listing
May 2014

The stem cell factor SOX2 regulates the tumorigenic potential in human gastric cancer cells.

Carcinogenesis 2014 Apr 9;35(4):942-50. Epub 2013 Dec 9.

Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, 81675 Munich, Germany.

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http://dx.doi.org/10.1093/carcin/bgt410DOI Listing
April 2014

Caveolin-1 protects B6129 mice against Helicobacter pylori gastritis.

PLoS Pathog 2013 11;9(4):e1003251. Epub 2013 Apr 11.

Department of Medicine II, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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http://dx.doi.org/10.1371/journal.ppat.1003251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623771PMC
January 2014

Helicobacter pylori cytotoxin-associated gene A impairs human dendritic cell maturation and function through IL-10-mediated activation of STAT3.

J Immunol 2014 Jan 29;192(1):316-23. Epub 2013 Nov 29.

Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, 81675 Munich, Germany;

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http://dx.doi.org/10.4049/jimmunol.1302476DOI Listing
January 2014

Helicobacter pylori FliD protein is a highly sensitive and specific marker for serologic diagnosis of H. pylori infection.

Int J Med Microbiol 2013 Dec 3;303(8):618-23. Epub 2013 Sep 3.

Department of Pathobiology, School of Public Health and Institute of Public Health Research, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1016/j.ijmm.2013.08.005DOI Listing
December 2013

The Sox17CreERT2 knock-in mouse line displays spatiotemporal activation of Cre recombinase in distinct Sox17 lineage progenitors.

Genesis 2013 Nov 1;51(11):793-802. Epub 2013 Oct 1.

Institute of Stem Cell Research, Helmholtz Zentrum München, Neuherberg, Germany; Institute of Diabetes and Regeneration Research, Helmholtz Zentrum München, Neuherberg, Germany.

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http://dx.doi.org/10.1002/dvg.22714DOI Listing
November 2013

A new mouse model for studying EGFR-dependent gastric polyps.

Biochim Biophys Acta 2012 Aug 8;1822(8):1293-9. Epub 2012 May 8.

Institute of Molecular Animal Breeding and Biotechnology, and Laboratory for Functional Genome Analysis, Gene Center, LMU Munich, Munich, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S09254439120010
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http://dx.doi.org/10.1016/j.bbadis.2012.05.002DOI Listing
August 2012

Evidence for conserved function of γ-glutamyltranspeptidase in Helicobacter genus.

PLoS One 2012 14;7(2):e30543. Epub 2012 Feb 14.

Department of Food Hygiene and Environmental Health, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0030543PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279353PMC
July 2012

Genetic variants of toll-like receptor 2 and 5, helicobacter pylori infection, and risk of gastric cancer and its precursors in a chinese population.

Cancer Epidemiol Biomarkers Prev 2011 Dec 12;20(12):2594-602. Epub 2011 Oct 12.

Department of Cancer Epidemiology, Peking University Cancer Hospital & Institute, Beijing, China.

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http://dx.doi.org/10.1158/1055-9965.EPI-11-0702DOI Listing
December 2011

Synthesis of 5-acetyloxazoles and 1,2-diketones from β-alkoxy-β-ketoenamides and their subsequent transformations.

Chemistry 2011 Jun 26;17(27):7480-91. Epub 2011 May 26.

Institut für Chemie und Biochemie, Freie Universität Berlin, Takustr. 3, 14195 Berlin, Germany.

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http://dx.doi.org/10.1002/chem.201100382DOI Listing
June 2011

A key role for E-cadherin in intestinal homeostasis and Paneth cell maturation.

PLoS One 2010 Dec 14;5(12):e14325. Epub 2010 Dec 14.

Institute of Molecular Animal Breeding and Biotechnology, and Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, University of Munich, Munich, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0014325PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001873PMC
December 2010

Betacellulin stimulates growth of the mouse intestinal epithelium and increases adenoma multiplicity in Apc+/Min mice.

FEBS Lett 2008 Aug 24;582(19):2911-5. Epub 2008 Jul 24.

Institute of Molecular Animal Breeding and Biotechnology, Gene Center, LMU Munich, Feodor-Lynen-Strasse 25, Munich, Germany.

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http://dx.doi.org/10.1016/j.febslet.2008.07.026DOI Listing
August 2008

Inhibition of T-cell proliferation by Helicobacter pylori gamma-glutamyl transpeptidase.

Gastroenterology 2007 May 21;132(5):1820-33. Epub 2007 Feb 21.

Department of Medicine II, Technical University of Munich, Munich, Germany.

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http://dx.doi.org/10.1053/j.gastro.2007.02.031DOI Listing
May 2007

VacA-associated inhibition of T-cell function: reviewed and reconsidered.

Helicobacter 2006 Jun;11(3):144-6

II. Medical Department, Technical University of Munich, Munich, Germany.

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http://dx.doi.org/10.1111/j.1523-5378.2006.00393.xDOI Listing
June 2006

The Cdx4 mutation affects axial development and reveals an essential role of Cdx genes in the ontogenesis of the placental labyrinth in mice.

Development 2006 Feb 5;133(3):419-28. Epub 2006 Jan 5.

Hubrecht laboratory, Netherlands Institute for Developmental Biology, Utrecht.

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http://dx.doi.org/10.1242/dev.02216DOI Listing
February 2006

Correlation of the Helicobacter pylori adherence factor BabA with duodenal ulcer disease in four European countries.

FEMS Immunol Med Microbiol 2005 May;44(2):151-6

Department of Medical Biochemistry and Biophysics, Umeå University, SE-901 87 Umeå, Sweden.

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http://dx.doi.org/10.1016/j.femsim.2004.10.010DOI Listing
May 2005

Isolation and characterization of Rac1 pseudogenes (psi1Rac1-psi4Rac1) in the human genome.

Gene 2004 Oct;341:189-97

Department of Medicine/Division of Pulmonology and Critical Care, University of California, San Francisco, San Francisco, CA, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S037811190400386
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http://dx.doi.org/10.1016/j.gene.2004.06.045DOI Listing
October 2004

Synergistic effect of Helicobacter pylori virulence factors and interleukin-1 polymorphisms for the development of severe histological changes in the gastric mucosa.

J Infect Dis 2003 Jul 3;188(2):272-81. Epub 2003 Jul 3.

Department of Internal Medicine II and Gastroenterology, Bogenhausen Academic Teaching Hospital, Technical University of Munich, Ismaningerstrasse 22, 81675 Munich, Germany.

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http://dx.doi.org/10.1086/376458DOI Listing
July 2003

The NudA protein in the gastric pathogen Helicobacter pylori is an ubiquitous and constitutively expressed dinucleoside polyphosphate hydrolase.

J Biol Chem 2003 Apr 27;278(14):12574-8. Epub 2003 Jan 27.

Department of Bacteriology, Swedish Institute for Infectious Disease Control, 171 82 Solna, Sweden.

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http://dx.doi.org/10.1074/jbc.M212542200DOI Listing
April 2003

Pathogenesis of Helicobacter pylori infection.

Helicobacter 2002 ;7 Suppl 1:17-23

Laboratory of Molecular Gastroenterology, Department of Medicine II, Technical University of Munich, Germany.

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http://dx.doi.org/10.1046/j.1523-5378.7.s1.3.xDOI Listing
November 2002

Helicobacter pylori induces apoptosis of rat gastric parietal cells.

Am J Physiol Gastrointest Liver Physiol 2002 Aug;283(2):G309-18

Department of Medicine II, Technical University of Munich, Germany.

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http://dx.doi.org/10.1152/ajpgi.00546.2001DOI Listing
August 2002

The Helicobacter pylori blood group antigen-binding adhesin facilitates bacterial colonization and augments a nonspecific immune response.

J Immunol 2002 Mar;168(6):3033-41

Departments of Medicine II and Gastroenterology, Microbiology, and Pathology, Technical University of Munich, Munich, Germany.

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http://dx.doi.org/10.4049/jimmunol.168.6.3033DOI Listing
March 2002