Dr.  Markus Biburger - University of Erlangen-Nuremberg

Dr. Markus Biburger

University of Erlangen-Nuremberg

Germany

ORCID logohttps://orcid.org/0000-0002-9177-8402

Dr.  Markus Biburger - University of Erlangen-Nuremberg

Dr. Markus Biburger

Introduction

Primary Affiliation: University of Erlangen-Nuremberg - Germany

Experience

Friedrich Alexander Universität Erlangen-Nürnberg Naturwissenschaftliche Fakultät
Senior researcher, Lecturer, Assist. Professor (Privatdozent)
Biology Dept., Division of Genetics

Publications

22Publications

147Reads

548Profile Views

274PubMed Central Citations

Dissecting FcγR Regulation through a Multivalent Binding Model.

Cell Syst 2018 Jul 27;7(1):41-48.e5. Epub 2018 Jun 27.

Department of Bioengineering, Jonsson Comprehensive Cancer Center, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2018.05.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6062446PMC
July 2018
1 Read

bIgG time for large eaters: monocytes and macrophages as effector and target cells of antibody-mediated immune activation and repression.

Immunol Rev 2015 Nov;268(1):52-65

Department of Biology, Institute of Genetics, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1111/imr.12347DOI Listing
November 2015
4 Reads
6 Citations
10.120 Impact Factor

Three blocks are not enough--Blocking of the murine IgG receptor FcγRIV is crucial for proper characterization of cells by FACS analysis.

Eur J Immunol 2015 Sep 21;45(9):2694-7. Epub 2015 Jul 21.

Division of Genetics, Department of Biology, University of Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1002/eji.201545463DOI Listing
September 2015
30 Reads
3 Citations
4.034 Impact Factor

How immunoglobulin G antibodies kill target cells: revisiting an old paradigm.

Adv Immunol 2014 ;124:67-94

Institute of Genetics, Department of Biology, University of Erlangen-Nürnberg, Erlangen, Germany. Electronic address:

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http://dx.doi.org/10.1016/B978-0-12-800147-9.00003-0DOI Listing
May 2015
5 Reads
5 Citations
5.962 Impact Factor

B cells and CD22 are dispensable for the immediate antiinflammatory activity of intravenous immunoglobulins in vivo.

Eur J Immunol 2012 Dec 16;42(12):3302-9. Epub 2012 Oct 16.

Institute of Genetics, Department of Biology, University of Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.1002/eji.201242710DOI Listing
December 2012
5 Reads
10 Citations
4.034 Impact Factor

IVIg-mediated amelioration of ITP in mice is dependent on sialic acid and SIGNR1.

Eur J Immunol 2012 Apr;42(4):826-30

Institute of Genetics, Department of Biology, University of Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1002/eji.201142260DOI Listing
April 2012
9 Reads
22 Citations
4.034 Impact Factor

FcγRIIB: a modulator of cell activation and humoral tolerance.

Expert Rev Clin Immunol 2012 Mar;8(3):243-54

Institute of Genetics, Department of Biology, University of Erlangen Nürnberg, Staudtstr. 5, 91058 Erlangen, Germany.

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http://dx.doi.org/10.1586/eci.12.5DOI Listing
March 2012
7 Reads
7 Citations
3.342 Impact Factor

Low level of FcγRIII expression on murine natural killer cells.

Immunol Lett 2012 Mar 21;143(1):53-9. Epub 2012 Jan 21.

Institute of Genetics, Department of Biology, University of Erlangen-Nuernberg, Erlangen, Germany.

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http://dx.doi.org/10.1016/j.imlet.2012.01.002DOI Listing
March 2012
1 Read
4 Citations
2.512 Impact Factor

Monocyte subsets responsible for immunoglobulin G-dependent effector functions in vivo.

Immunity 2011 Dec 8;35(6):932-44. Epub 2011 Dec 8.

Department of Biology, University of Erlangen-Nuremberg, Erwin-Rommel-Str. 3, 91058 Erlangen, Germany.

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http://dx.doi.org/10.1016/j.immuni.2011.11.009DOI Listing
December 2011
7 Reads
37 Citations
21.561 Impact Factor

The role of Fcgamma receptors in murine autoimmune thrombocytopenia.

Ann Hematol 2010 Jul 24;89 Suppl 1:25-30. Epub 2010 Feb 24.

Laboratory for Experimental Immunology and Immunotherapy, Nikolaus-Fiebiger-Centre for Molecular Medicine, Medical Department III, University of Erlangen-Nuremberg, Glückstr. 6, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1007/s00277-010-0915-3DOI Listing
July 2010
1 Read
2.634 Impact Factor

Mechanisms of action of intravenous immunoglobulins.

Expert Rev Clin Immunol 2010 May;6(3):425-34

Department of Biology, Institute of Genetics, University of Erlangen-Nuremberg, Staudtstr. 5, 91058 Erlangen, Germany.

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http://dx.doi.org/10.1586/eci.10.9DOI Listing
May 2010
2 Reads
7 Citations
3.342 Impact Factor

Pivotal Advance: Heme oxygenase 1 expression by human CD4+ T cells is not sufficient for their development of immunoregulatory capacity.

J Leukoc Biol 2010 Feb 1;87(2):193-202. Epub 2009 Oct 1.

Nikolaus Fiebiger Center for Molecular Medicine, Medical Department III, University Hospital of Erlangen, Germany.

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http://doi.wiley.com/10.1189/jlb.0508280
Publisher Site
http://dx.doi.org/10.1189/jlb.0508280DOI Listing
February 2010
4 Reads
11 Citations
4.290 Impact Factor

The neuropeptide calcitonin gene-related peptide (CGRP) prevents inflammatory liver injury in mice.

J Hepatol 2009 Aug 3;51(2):342-53. Epub 2009 May 3.

Institute of Experimental and Clinical Pharmacology and Toxicology, University of Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.1016/j.jhep.2009.03.022DOI Listing
August 2009
3 Reads
6 Citations
11.340 Impact Factor

Activation-induced NKT cell hyporesponsiveness protects from alpha-galactosylceramide hepatitis and is independent of active transregulatory factors.

J Leukoc Biol 2008 Jul 11;84(1):264-79. Epub 2008 Apr 11.

Laboratory for Experimental Immunology and Immunotherapy, Nikolaus-Fiebiger-Center for Molecular Medicine, Medical Department III, University Hospital Erlangen, Germany.

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http://dx.doi.org/10.1189/jlb.0607352DOI Listing
July 2008
10 Citations
4.290 Impact Factor

IL-10, regulatory T cells, and Kupffer cells mediate tolerance in concanavalin A-induced liver injury in mice.

Hepatology 2007 Feb;45(2):475-85

Institute of Experimental and Clinical Pharmacology and Toxicology, University ofErlangen-Nuremberg, Fahrstrasse 17, D-91054 Erlangen, Germany.

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http://dx.doi.org/10.1002/hep.21498DOI Listing
February 2007
4 Reads
68 Citations
11.055 Impact Factor

Kupffer cell-expressed membrane-bound TNF mediates melphalan hepatotoxicity via activation of both TNF receptors.

J Immunol 2005 Sep;175(6):4076-83

Biochemical Pharmacology, University of Konstanz, Konstanz, Germany.

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September 2005
5 Reads
7 Citations
4.922 Impact Factor

Alpha-galactosylceramide-induced liver injury in mice is mediated by TNF-alpha but independent of Kupffer cells.

J Immunol 2005 Aug;175(3):1540-50

Institute of Experimental and Clinical Pharmacology and Toxicology, University of Erlangen-Nuremberg, Erlangen, Germany.

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August 2005
47 Citations
4.922 Impact Factor

A novel bispecific tetravalent antibody fusion protein to target costimulatory activity for T-cell activation to tumor cells overexpressing ErbB2/HER2.

J Mol Biol 2005 Mar 22;346(5):1299-311. Epub 2005 Jan 22.

Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus, Paul-Ehrlich-Strasse 42-44, 60596 Frankfurt am Main, Germany.

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http://dx.doi.org/10.1016/j.jmb.2004.12.052DOI Listing
March 2005
4 Reads
4 Citations
4.333 Impact Factor

Recombinant immunotoxins and retargeted killer cells: employing engineered antibody fragments for tumor-specific targeting of cytotoxic effectors.

Cancer Immunol Immunother 2004 Mar 24;53(3):217-26. Epub 2003 Dec 24.

Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus, Paul-Ehrlich-Strasse 42-44, 60596, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1007/s00262-003-0482-8DOI Listing
March 2004
3 Reads
3 Citations
3.941 Impact Factor

Neurokinin-1 receptor antagonists protect mice from CD95- and tumor necrosis factor-alpha-mediated apoptotic liver damage.

J Pharmacol Exp Ther 2004 Mar 14;308(3):1174-80. Epub 2003 Nov 14.

Institute of Experimental and Clinical Pharmacology and Toxicology, University of Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.1124/jpet.103.059329DOI Listing
March 2004
2 Reads
7 Citations
3.972 Impact Factor