Markku J Savolainen

Markku J Savolainen

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Markku J Savolainen

Publications by authors named "Markku J Savolainen"

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Opportunities and challenges of behavior change support systems for enhancing habit formation: A qualitative study.

J Biomed Inform 2018 08 21;84:82-92. Epub 2018 Jun 21.

Research Center for Internal Medicine, University of Oulu, Oulu, Finland; Department of Internal Medicine, Oulu University Hospital, Oulu, Finland; Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1016/j.jbi.2018.06.012DOI Listing
August 2018

Elevated Levels of Plasma IgA Autoantibodies against Oxidized LDL Found in Proliferative Diabetic Retinopathy but Not in Nonproliferative Retinopathy.

J Diabetes Res 2016 20;2016:2614153. Epub 2016 Dec 20.

PEDEGO Research Unit, Department of Ophthalmology, Medical Research Center (MRC Oulu), Oulu University Hospital and University of Oulu, Oulu, Finland; Research Unit of Internal Medicine, Medical Research Center Oulu (MRC Oulu), Oulu University Hospital and University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1155/2016/2614153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206457PMC
May 2017

Epidemiology: disease associations and modulators of HDL-related biomarkers.

Handb Exp Pharmacol 2015 ;224:259-83

Department of Internal Medicine, Institute of Clinical Medicine, University of Oulu, Kajaanintie 50, 5000, 90014, Oulu, Finland,

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http://dx.doi.org/10.1007/978-3-319-09665-0_7DOI Listing
April 2015

Fat mass- and obesity-associated gene Fto affects the dietary response in mouse white adipose tissue.

Sci Rep 2015 Mar 18;5:9233. Epub 2015 Mar 18.

1] Biocenter Oulu, University of Oulu, Oulu, Finland [2] Institute of Clinical Medicine, Department of Internal Medicine, University of Oulu, Oulu, Finland [3] Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1038/srep09233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363842PMC
March 2015

Healthy Nordic diet downregulates the expression of genes involved in inflammation in subcutaneous adipose tissue in individuals with features of the metabolic syndrome.

Am J Clin Nutr 2015 Jan 19;101(1):228-39. Epub 2014 Nov 19.

From the Institute of Public Health and Clinical Nutrition (MK, J Paananen, VdM, US, J Pihlajamäki, KSP, and MU) and the Institute of Biomedicine (CC), University of Eastern Finland, Kuopio, Finland; the Institute of Clinical Medicine, Clinical Nutrition (US and J Pihlajamäki) and Research Unit (MU), Kuopio University Hospital, Kuopio, Finland; the Department of Health, Nutrition and Management, Faculty of Health Sciences, Oslo, Norway, and Akershus University College of Applied Sciences, Oslo, Norway (SMU and MM); the Department of Medicine (H7), Karolinska Institute, Stockholm, Sweden (ID, PA, ED, and ES); the Unit for Nutrition Research, University of Iceland and Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland (IG and IT); Biomedical Nutrition, Pure and Applied Biochemistry, Lund University, Lund, Sweden (LC and BÅ); the Departments of Endocrinology (ML-O) and Clinical Nutrition (BÅ), Skåne University Hospital, Lund, Sweden; the Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden (FR and UR); the Institute of Clinical Medicine, Department of Internal Medicine and Biocenter Oulu, University of Oulu, and Medical Research Center, Oulu University Hospital, Oulu, Finland (MJS and JH); University of Copenhagen, Faculty of Science, Department of Human Nutrition, Copenhagen, Denmark (LOD); Institute of Biomedicine, University of Oulu, Oulu, Finland (K-HH); the Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark (KH and LB); and VTT Technical Research Centre of Finland, Espoo, Finland (KSP).

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http://dx.doi.org/10.3945/ajcn.114.092783DOI Listing
January 2015

Life course structural equation model of the effects of prenatal and postnatal growth on adult blood pressure.

J Epidemiol Community Health 2014 Dec 8;68(12):1161-7. Epub 2014 Aug 8.

Institute of Health Sciences, University of Oulu, Oulu, Finland Biocenter Oulu, Oulu, Finland Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, Imperial College London, London, UK Department of Children and Young People and Families, National Institute for Health and Welfare, Oulu, Finland Unit of Primary Care, Oulu University Hospital, Oulu, Finland.

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http://dx.doi.org/10.1136/jech-2013-203661DOI Listing
December 2014

Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change.

PLoS Med 2014 Dec 9;11(12):e1001765. Epub 2014 Dec 9.

Computational Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland; NMR Metabolomics Laboratory, School of Pharmacy, University of Eastern Finland, Kuopio, Finland; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom; Oulu University Hospital, Oulu, Finland; Computational Medicine, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1001765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260795PMC
December 2014

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis.

Authors:
Tove Fall Sara Hägg Reedik Mägi Alexander Ploner Krista Fischer Momoko Horikoshi Antti-Pekka Sarin Gudmar Thorleifsson Claes Ladenvall Mart Kals Maris Kuningas Harmen H M Draisma Janina S Ried Natalie R van Zuydam Ville Huikari Massimo Mangino Emily Sonestedt Beben Benyamin Christopher P Nelson Natalia V Rivera Kati Kristiansson Huei-Yi Shen Aki S Havulinna Abbas Dehghan Louise A Donnelly Marika Kaakinen Marja-Liisa Nuotio Neil Robertson Renée F A G de Bruijn M Arfan Ikram Najaf Amin Anthony J Balmforth Peter S Braund Alexander S F Doney Angela Döring Paul Elliott Tõnu Esko Oscar H Franco Solveig Gretarsdottir Anna-Liisa Hartikainen Kauko Heikkilä Karl-Heinz Herzig Hilma Holm Jouke Jan Hottenga Elina Hyppönen Thomas Illig Aaron Isaacs Bo Isomaa Lennart C Karssen Johannes Kettunen Wolfgang Koenig Kari Kuulasmaa Tiina Laatikainen Jaana Laitinen Cecilia Lindgren Valeriya Lyssenko Esa Läärä Nigel W Rayner Satu Männistö Anneli Pouta Wolfgang Rathmann Fernando Rivadeneira Aimo Ruokonen Markku J Savolainen Eric J G Sijbrands Kerrin S Small Jan H Smit Valgerdur Steinthorsdottir Ann-Christine Syvänen Anja Taanila Martin D Tobin Andre G Uitterlinden Sara M Willems Gonneke Willemsen Jacqueline Witteman Markus Perola Alun Evans Jean Ferrières Jarmo Virtamo Frank Kee David-Alexandre Tregouet Dominique Arveiler Philippe Amouyel Marco M Ferrario Paolo Brambilla Alistair S Hall Andrew C Heath Pamela A F Madden Nicholas G Martin Grant W Montgomery John B Whitfield Antti Jula Paul Knekt Ben Oostra Cornelia M van Duijn Brenda W J H Penninx George Davey Smith Jaakko Kaprio Nilesh J Samani Christian Gieger Annette Peters H Erich Wichmann Dorret I Boomsma Eco J C de Geus TiinaMaija Tuomi Chris Power Christopher J Hammond Tim D Spector Lars Lind Marju Orho-Melander Colin Neil Alexander Palmer Andrew D Morris Leif Groop Marjo-Riitta Järvelin Veikko Salomaa Erkki Vartiainen Albert Hofman Samuli Ripatti Andres Metspalu Unnur Thorsteinsdottir Kari Stefansson Nancy L Pedersen Mark I McCarthy Erik Ingelsson Inga Prokopenko

PLoS Med 2013 25;10(6):e1001474. Epub 2013 Jun 25.

Molecular Epidemiology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1371/journal.pmed.1001474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3692470PMC
March 2014

Ethanol-induced impairment of polyamine homeostasis--a potential cause of neural tube defect and intrauterine growth restriction in fetal alcohol syndrome.

Biochem Biophys Res Commun 2014 Mar 25;446(1):173-8. Epub 2014 Feb 25.

Institute of Clinical Medicine, Department of Internal Medicine, and Biocenter Oulu, University of Oulu, Oulu, Finland; Medical Research Center, Oulu University Hospital, Oulu, Finland.

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http://dx.doi.org/10.1016/j.bbrc.2014.02.079DOI Listing
March 2014

Statin therapy worsens insulin sensitivity in women with polycystic ovary syndrome (PCOS): a prospective, randomized, double-blind, placebo-controlled study.

J Clin Endocrinol Metab 2013 Dec 23;98(12):4798-807. Epub 2013 Oct 23.

Department of Obstetrics and Gynecology, Helsinki University Central Hospital and Helsinki University, P.O. Box 140, 00029 HUS, Finland.

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http://dx.doi.org/10.1210/jc.2013-2674DOI Listing
December 2013

Interleukin 8 promoter polymorphism predicts the initial response to bevacizumab treatment for exudative age-related macular degeneration.

Retina 2013 Oct;33(9):1815-27

*Department of Ophthalmology, Helsinki University Central Hospital, Helsinki, Finland †Department of Medical Genetics, University of Helsinki, Helsinki, Finland Departments of ‡Ophthalmology, Institute of Clinical Medicine, and §Internal Medicine, Clinical Research Center and Biocenter Oulu, University of Oulu, Oulu, Finland ¶Department of Clinical Chemistry, Oulu University Hospital, Oulu, Finland **Department of Biosciences, University of Helsinki, Helsinki, Finland.

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http://pdfs.journals.lww.com/retinajournal/2013/10000/Interl
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/IAE.0b013e318285cf92DOI Listing
October 2013

Plasma alkylresorcinols reflect important whole-grain components of a healthy Nordic diet.

J Nutr 2013 Sep 10;143(9):1383-90. Epub 2013 Jul 10.

Unit for Nutrition Research, Landspitali, The National University of Iceland, Faculty of Food Science and Nutrition and School of Health Sciences, University of Iceland, Reykjavík, Iceland.

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http://dx.doi.org/10.3945/jn.113.175588DOI Listing
September 2013

Long telomeres in blood leukocytes are associated with a high risk of ascending aortic aneurysm.

PLoS One 2012 29;7(11):e50828. Epub 2012 Nov 29.

Institute of Clinical Medicine, Department of Internal Medicine, Clinical Research Center, Oulu University Hospital and University of Oulu, Oulu, Finland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0050828PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510165PMC
May 2013

Low plasma antibodies specific for phosphatidylethanol in alcohol abusers and patients with alcoholic pancreatitis.

Addict Biol 2012 Nov 11;17(6):1057-67. Epub 2011 Feb 11.

Clinical Research Center, Oulu University Hospital, Finland.

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http://dx.doi.org/10.1111/j.1369-1600.2010.00279.xDOI Listing
November 2012

Plasma levels of antibodies against oxidized LDL are inherited but not associated with HDL-cholesterol level in families with early coronary heart disease.

Atherosclerosis 2012 Sep 28;224(1):123-8. Epub 2012 Jun 28.

Department of Internal Medicine, Biocenter Oulu and Clinical Research Center, University of Oulu, Aapistie 5A, 90220 Oulu, Finland.

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http://dx.doi.org/10.1016/j.atherosclerosis.2012.06.056DOI Listing
September 2012

The interplay between lipoprotein phenotypes, adiponectin, and alcohol consumption.

Ann Med 2012 Aug 11;44(5):513-22. Epub 2011 Nov 11.

Institute of Clinical Medicine, Department of Internal Medicine, Biocenter Oulu and Clinical Research Center, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.3109/07853890.2011.611529DOI Listing
August 2012

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.

Authors:
John C Chambers Weihua Zhang Joban Sehmi Xinzhong Li Mark N Wass Pim Van der Harst Hilma Holm Serena Sanna Maryam Kavousi Sebastian E Baumeister Lachlan J Coin Guohong Deng Christian Gieger Nancy L Heard-Costa Jouke-Jan Hottenga Brigitte Kühnel Vinod Kumar Vasiliki Lagou Liming Liang Jian'an Luan Pedro Marques Vidal Irene Mateo Leach Paul F O'Reilly John F Peden Nilufer Rahmioglu Pasi Soininen Elizabeth K Speliotes Xin Yuan Gudmar Thorleifsson Behrooz Z Alizadeh Larry D Atwood Ingrid B Borecki Morris J Brown Pimphen Charoen Francesco Cucca Debashish Das Eco J C de Geus Anna L Dixon Angela Döring Georg Ehret Gudmundur I Eyjolfsson Martin Farrall Nita G Forouhi Nele Friedrich Wolfram Goessling Daniel F Gudbjartsson Tamara B Harris Anna-Liisa Hartikainen Simon Heath Gideon M Hirschfield Albert Hofman Georg Homuth Elina Hyppönen Harry L A Janssen Toby Johnson Antti J Kangas Ido P Kema Jens P Kühn Sandra Lai Mark Lathrop Markus M Lerch Yun Li T Jake Liang Jing-Ping Lin Ruth J F Loos Nicholas G Martin Miriam F Moffatt Grant W Montgomery Patricia B Munroe Kiran Musunuru Yusuke Nakamura Christopher J O'Donnell Isleifur Olafsson Brenda W Penninx Anneli Pouta Bram P Prins Inga Prokopenko Ralf Puls Aimo Ruokonen Markku J Savolainen David Schlessinger Jeoffrey N L Schouten Udo Seedorf Srijita Sen-Chowdhry Katherine A Siminovitch Johannes H Smit Timothy D Spector Wenting Tan Tanya M Teslovich Taru Tukiainen Andre G Uitterlinden Melanie M Van der Klauw Ramachandran S Vasan Chris Wallace Henri Wallaschofski H-Erich Wichmann Gonneke Willemsen Peter Würtz Chun Xu Laura M Yerges-Armstrong Goncalo R Abecasis Kourosh R Ahmadi Dorret I Boomsma Mark Caulfield William O Cookson Cornelia M van Duijn Philippe Froguel Koichi Matsuda Mark I McCarthy Christa Meisinger Vincent Mooser Kirsi H Pietiläinen Gunter Schumann Harold Snieder Michael J E Sternberg Ronald P Stolk Howard C Thomas Unnur Thorsteinsdottir Manuela Uda Gérard Waeber Nicholas J Wareham Dawn M Waterworth Hugh Watkins John B Whitfield Jacqueline C M Witteman Bruce H R Wolffenbuttel Caroline S Fox Mika Ala-Korpela Kari Stefansson Peter Vollenweider Henry Völzke Eric E Schadt James Scott Marjo-Riitta Järvelin Paul Elliott Jaspal S Kooner

Nat Genet 2011 Oct 16;43(11):1131-8. Epub 2011 Oct 16.

Epidemiology and Biostatistics, Imperial College London, Norfolk Place, London, UK.

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http://hmg.oxfordjournals.org/content/early/2012/09/04/hmg.d
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http://www.nature.com/doifinder/10.1038/ng.970
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http://dx.doi.org/10.1038/ng.970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482372PMC
October 2011

Effect of weight loss intervention on the association between eating behaviour measured by TFEQ-18 and dietary intake in adults.

Appetite 2011 Feb 16;56(1):156-62. Epub 2010 Oct 16.

University of Oulu, Institute of Clinical Medicine, Department of Internal Medicine, P.O. Box 5000, FI-90014 Oulu, Finland.

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http://dx.doi.org/10.1016/j.appet.2010.10.004DOI Listing
February 2011

Characterization of systemic metabolic phenotypes associated with subclinical atherosclerosis.

Mol Biosyst 2011 Feb 5;7(2):385-93. Epub 2010 Nov 5.

Computational Medicine Research Group, Institute of Clinical Medicine, University of Oulu and Biocenter Oulu, PO Box 5000, FI-90014, Oulu, Finland.

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http://dx.doi.org/10.1039/c0mb00066cDOI Listing
February 2011

Effects of low-dose liquorice alone or in combination with hydrochlorothiazide on the plasma potassium in healthy volunteers.

Blood Press 2009 ;18(4):192-5

Department of Internal Medicine, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1080/08037050903072515DOI Listing
December 2010

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.

Authors:
Elizabeth K Speliotes Cristen J Willer Sonja I Berndt Keri L Monda Gudmar Thorleifsson Anne U Jackson Hana Lango Allen Cecilia M Lindgren Jian'an Luan Reedik Mägi Joshua C Randall Sailaja Vedantam Thomas W Winkler Lu Qi Tsegaselassie Workalemahu Iris M Heid Valgerdur Steinthorsdottir Heather M Stringham Michael N Weedon Eleanor Wheeler Andrew R Wood Teresa Ferreira Robert J Weyant Ayellet V Segrè Karol Estrada Liming Liang James Nemesh Ju-Hyun Park Stefan Gustafsson Tuomas O Kilpeläinen Jian Yang Nabila Bouatia-Naji Tõnu Esko Mary F Feitosa Zoltán Kutalik Massimo Mangino Soumya Raychaudhuri Andre Scherag Albert Vernon Smith Ryan Welch Jing Hua Zhao Katja K Aben Devin M Absher Najaf Amin Anna L Dixon Eva Fisher Nicole L Glazer Michael E Goddard Nancy L Heard-Costa Volker Hoesel Jouke-Jan Hottenga Asa Johansson Toby Johnson Shamika Ketkar Claudia Lamina Shengxu Li Miriam F Moffatt Richard H Myers Narisu Narisu John R B Perry Marjolein J Peters Michael Preuss Samuli Ripatti Fernando Rivadeneira Camilla Sandholt Laura J Scott Nicholas J Timpson Jonathan P Tyrer Sophie van Wingerden Richard M Watanabe Charles C White Fredrik Wiklund Christina Barlassina Daniel I Chasman Matthew N Cooper John-Olov Jansson Robert W Lawrence Niina Pellikka Inga Prokopenko Jianxin Shi Elisabeth Thiering Helene Alavere Maria T S Alibrandi Peter Almgren Alice M Arnold Thor Aspelund Larry D Atwood Beverley Balkau Anthony J Balmforth Amanda J Bennett Yoav Ben-Shlomo Richard N Bergman Sven Bergmann Heike Biebermann Alexandra I F Blakemore Tanja Boes Lori L Bonnycastle Stefan R Bornstein Morris J Brown Thomas A Buchanan Fabio Busonero Harry Campbell Francesco P Cappuccio Christine Cavalcanti-Proença Yii-Der Ida Chen Chih-Mei Chen Peter S Chines Robert Clarke Lachlan Coin John Connell Ian N M Day Martin den Heijer Jubao Duan Shah Ebrahim Paul Elliott Roberto Elosua Gudny Eiriksdottir Michael R Erdos Johan G Eriksson Maurizio F Facheris Stephan B Felix Pamela Fischer-Posovszky Aaron R Folsom Nele Friedrich Nelson B Freimer Mao Fu Stefan Gaget Pablo V Gejman Eco J C Geus Christian Gieger Anette P Gjesing Anuj Goel Philippe Goyette Harald Grallert Jürgen Grässler Danielle M Greenawalt Christopher J Groves Vilmundur Gudnason Candace Guiducci Anna-Liisa Hartikainen Neelam Hassanali Alistair S Hall Aki S Havulinna Caroline Hayward Andrew C Heath Christian Hengstenberg Andrew A Hicks Anke Hinney Albert Hofman Georg Homuth Jennie Hui Wilmar Igl Carlos Iribarren Bo Isomaa Kevin B Jacobs Ivonne Jarick Elizabeth Jewell Ulrich John Torben Jørgensen Pekka Jousilahti Antti Jula Marika Kaakinen Eero Kajantie Lee M Kaplan Sekar Kathiresan Johannes Kettunen Leena Kinnunen Joshua W Knowles Ivana Kolcic Inke R König Seppo Koskinen Peter Kovacs Johanna Kuusisto Peter Kraft Kirsti Kvaløy Jaana Laitinen Olivier Lantieri Chiara Lanzani Lenore J Launer Cecile Lecoeur Terho Lehtimäki Guillaume Lettre Jianjun Liu Marja-Liisa Lokki Mattias Lorentzon Robert N Luben Barbara Ludwig Paolo Manunta Diana Marek Michel Marre Nicholas G Martin Wendy L McArdle Anne McCarthy Barbara McKnight Thomas Meitinger Olle Melander David Meyre Kristian Midthjell Grant W Montgomery Mario A Morken Andrew P Morris Rosanda Mulic Julius S Ngwa Mari Nelis Matt J Neville Dale R Nyholt Christopher J O'Donnell Stephen O'Rahilly Ken K Ong Ben Oostra Guillaume Paré Alex N Parker Markus Perola Irene Pichler Kirsi H Pietiläinen Carl G P Platou Ozren Polasek Anneli Pouta Suzanne Rafelt Olli Raitakari Nigel W Rayner Martin Ridderstråle Winfried Rief Aimo Ruokonen Neil R Robertson Peter Rzehak Veikko Salomaa Alan R Sanders Manjinder S Sandhu Serena Sanna Jouko Saramies Markku J Savolainen Susann Scherag Sabine Schipf Stefan Schreiber Heribert Schunkert Kaisa Silander Juha Sinisalo David S Siscovick Jan H Smit Nicole Soranzo Ulla Sovio Jonathan Stephens Ida Surakka Amy J Swift Mari-Liis Tammesoo Jean-Claude Tardif Maris Teder-Laving Tanya M Teslovich John R Thompson Brian Thomson Anke Tönjes Tiinamaija Tuomi Joyce B J van Meurs Gert-Jan van Ommen Vincent Vatin Jorma Viikari Sophie Visvikis-Siest Veronique Vitart Carla I G Vogel Benjamin F Voight Lindsay L Waite Henri Wallaschofski G Bragi Walters Elisabeth Widen Susanna Wiegand Sarah H Wild Gonneke Willemsen Daniel R Witte Jacqueline C Witteman Jianfeng Xu Qunyuan Zhang Lina Zgaga Andreas Ziegler Paavo Zitting John P Beilby I Sadaf Farooqi Johannes Hebebrand Heikki V Huikuri Alan L James Mika Kähönen Douglas F Levinson Fabio Macciardi Markku S Nieminen Claes Ohlsson Lyle J Palmer Paul M Ridker Michael Stumvoll Jacques S Beckmann Heiner Boeing Eric Boerwinkle Dorret I Boomsma Mark J Caulfield Stephen J Chanock Francis S Collins L Adrienne Cupples George Davey Smith Jeanette Erdmann Philippe Froguel Henrik Grönberg Ulf Gyllensten Per Hall Torben Hansen Tamara B Harris Andrew T Hattersley Richard B Hayes Joachim Heinrich Frank B Hu Kristian Hveem Thomas Illig Marjo-Riitta Jarvelin Jaakko Kaprio Fredrik Karpe Kay-Tee Khaw Lambertus A Kiemeney Heiko Krude Markku Laakso Debbie A Lawlor Andres Metspalu Patricia B Munroe Willem H Ouwehand Oluf Pedersen Brenda W Penninx Annette Peters Peter P Pramstaller Thomas Quertermous Thomas Reinehr Aila Rissanen Igor Rudan Nilesh J Samani Peter E H Schwarz Alan R Shuldiner Timothy D Spector Jaakko Tuomilehto Manuela Uda André Uitterlinden Timo T Valle Martin Wabitsch Gérard Waeber Nicholas J Wareham Hugh Watkins James F Wilson Alan F Wright M Carola Zillikens Nilanjan Chatterjee Steven A McCarroll Shaun Purcell Eric E Schadt Peter M Visscher Themistocles L Assimes Ingrid B Borecki Panos Deloukas Caroline S Fox Leif C Groop Talin Haritunians David J Hunter Robert C Kaplan Karen L Mohlke Jeffrey R O'Connell Leena Peltonen David Schlessinger David P Strachan Cornelia M van Duijn H-Erich Wichmann Timothy M Frayling Unnur Thorsteinsdottir Gonçalo R Abecasis Inês Barroso Michael Boehnke Kari Stefansson Kari E North Mark I McCarthy Joel N Hirschhorn Erik Ingelsson Ruth J F Loos

Nat Genet 2010 Nov 10;42(11):937-48. Epub 2010 Oct 10.

Metabolism Initiative and Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.

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http://www.genome.gov/pages/research/dir/bmistudy.pdf
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http://www.nature.com/doifinder/10.1038/ng.686
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http://dx.doi.org/10.1038/ng.686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014648PMC
November 2010

Genetic and environmental determinants of total and high-molecular weight adiponectin in families with low HDL-cholesterol and early onset coronary heart disease.

Atherosclerosis 2010 Jun 21;210(2):479-85. Epub 2009 Dec 21.

Institute of Clinical Medicine, Department of Internal Medicine and Biocenter Oulu, University of Oulu and Clinical Research Center, Oulu University Hospital, Oulu, Finland.

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http://dx.doi.org/10.1016/j.atherosclerosis.2009.12.022DOI Listing
June 2010

Genome scan for loci regulating HDL cholesterol levels in Finnish extended pedigrees with early coronary heart disease.

Eur J Hum Genet 2010 May 25;18(5):604-13. Epub 2009 Nov 25.

Institute of Clinical Medicine, Department of Internal Medicine and Biocenter Oulu, University of Oulu and Clinical Research Center, Oulu University Hospital, Oulu, Finland.

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http://dx.doi.org/10.1038/ejhg.2009.202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987327PMC
May 2010

High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism.

Analyst 2009 Sep 30;134(9):1781-5. Epub 2009 Jul 30.

NMR Metabonomics Laboratory, Laboratory of Chemistry, Department of Biosciences, University of Kuopio, Kuopio, Finland.

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http://dx.doi.org/10.1039/b910205aDOI Listing
September 2009

The effect of eating behavior on weight loss and maintenance during a lifestyle intervention.

Prev Med 2009 Aug 4;49(1):32-8. Epub 2009 May 4.

University of Oulu, Clinical Research Center, Department of Internal Medicine, P.O. Box 5000, FI-90014 Oulu, Finland.

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http://dx.doi.org/10.1016/j.ypmed.2009.04.011DOI Listing
August 2009

Variation in the vascular endothelial growth factor gene, carotid intima-media thickness and the risk of acute myocardial infarction.

Scand J Clin Lab Invest 2009 ;69(3):335-43

Institute of Clinical Medicine, Department of Internal Medicine, Oulu University Hospital and Biocenter Oulu, Finland.

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http://dx.doi.org/10.1080/00365510802607520DOI Listing
July 2009

Low-density lipoprotein clearance in patients with chronic renal failure.

Nephrol Dial Transplant 2009 Jul 5;24(7):2131-5. Epub 2009 Feb 5.

Institute of Clinical Medicine, Department of Internal Medicine, Biocenter Oulu, Oulu, Finland.

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https://ndt.oxfordjournals.org/content/early/2009/02/05/ndt.
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http://ndt.oxfordjournals.org/cgi/doi/10.1093/ndt/gfp026
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http://dx.doi.org/10.1093/ndt/gfp026DOI Listing
July 2009

High vitreous concentration of vascular endothelial growth factor in diabetic patients with proliferative retinopathy using statins.

Ann Med 2008 ;40(3):209-14

Department of Internal Medicine and Clinical Research Center, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1080/07853890701749209DOI Listing
June 2008

Immunological detection of in vitro formed phosphatidylethanol--an alcohol biomarker--with monoclonal antibodies.

Alcohol Clin Exp Res 2008 Jun 26;32(6):921-8. Epub 2008 Apr 26.

Institute of Clinical Medicine, Department of Internal Medicine, University of Oulu, Clinical Research Center, Oulu University Hospital, Oulu, Finland.

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http://dx.doi.org/10.1111/j.1530-0277.2008.00656.xDOI Listing
June 2008

HDL2 of heavy alcohol drinkers enhances cholesterol efflux from raw macrophages via phospholipid-rich HDL 2b particles.

Alcohol Clin Exp Res 2008 Jun;32(6):991-1000

Department of Internal Medicine, Clinical Research Center, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1111/j.1530-0277.2008.00660.xDOI Listing
June 2008

Biochemical markers of alcoholism.

Clin Chem Lab Med 2007 ;45(8):953-61

Department of Internal Medicine, Clinical Research Center, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1515/CCLM.2007.190DOI Listing
January 2008

1H NMR metabonomics of plasma lipoprotein subclasses: elucidation of metabolic clustering by self-organising maps.

NMR Biomed 2007 Nov;20(7):658-72

Laboratory of Computational Engineering, Systems Biology and Bioinformation Technology, Helsinki University of Technology, Finland.

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http://dx.doi.org/10.1002/nbm.1123DOI Listing
November 2007

A novel Bayesian approach to quantify clinical variables and to determine their spectroscopic counterparts in 1H NMR metabonomic data.

BMC Bioinformatics 2007 May 3;8 Suppl 2:S8. Epub 2007 May 3.

Laboratory of Computational Engineering, Systems Biology and Bioinformation Technology, Helsinki University of Technology, Finland.

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http://dx.doi.org/10.1186/1471-2105-8-S2-S8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892077PMC
May 2007

Effects of phosphatidylethanol on mouse adipocyte differentiation and expression of stearoyl-CoA desaturase 1.

Alcohol Clin Exp Res 2007 Mar;31(3):376-82

Department of Internal Medicine, Clinical Research Center, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1111/j.1530-0277.2006.00332.xDOI Listing
March 2007

Defective glycosylation of cholesteryl ester transfer protein in plasma from alcohol abusers.

Alcohol Alcohol 2006 Jan-Feb;41(1):18-23. Epub 2005 Oct 3.

Department of Internal Medicine, University of Oulu, PO Box 5000, 90014 Oulu, Finland.

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http://dx.doi.org/10.1093/alcalc/agh216DOI Listing
April 2006

Phosphatidylethanol in high density lipoproteins increases the vascular endothelial growth factor in smooth muscle cells.

Atherosclerosis 2005 Jun;180(2):263-9

Department of Internal Medicine, University of Oulu, PO Box 5000, FIN-90014 Oulu, Finland.

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http://dx.doi.org/10.1016/j.atherosclerosis.2004.12.041DOI Listing
June 2005

Transfer of phosphatidylethanol between lipoproteins.

Alcohol Clin Exp Res 2004 Nov;28(11):1638-42

Department of Internal Medicine, University of Oulu, P.O. Box 5000, FIN-90014 Oulu, Finland.

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http://dx.doi.org/10.1097/01.alc.0000145788.72810.d6DOI Listing
November 2004

Lipoprotein-associated phosphatidylethanol increases the plasma concentration of vascular endothelial growth factor.

Arterioscler Thromb Vasc Biol 2004 Jun 15;24(6):1037-42. Epub 2004 Apr 15.

Department of Internal Medicine, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1161/01.ATV.0000128409.62292.d6DOI Listing
June 2004

Effects of ethanol on lipids and atherosclerosis.

Pathophysiology 2004 Apr;10(2):93-103

Department of Internal Medicine and Biocenter Oulu, University of Oulu, P.O. Box 5000, FIN-90014 Oulu, Finland.

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http://dx.doi.org/10.1016/j.pathophys.2003.10.009DOI Listing
April 2004

Effects of estrogen replacement therapy on natriuretic peptides and blood pressure.

Maturitas 2004 Mar;47(3):201-8

Department of Internal Medicine, Biocenter Oulu, University of Oulu, P.O. Box 20, 90029 OYS, Oulu, Finland.

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http://dx.doi.org/10.1016/S0378-5122(03)00279-2DOI Listing
March 2004

High-density lipoprotein increases the abundance of eNOS protein in human vascular endothelial cells by increasing its half-life.

J Am Coll Cardiol 2003 Jun;41(12):2288-97

Molecular Cardiology Research Institute and Department of Medicine, New England Medical Center Hospitals, Inc., Tufts University School of Medicine, Boston, Massachusetts 02111, USA.

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http://dx.doi.org/10.1016/s0735-1097(03)00481-9DOI Listing
June 2003

The signal sequence polymorphism of the MnSOD gene is associated with the degree of carotid atherosclerosis.

Atherosclerosis 2003 May;168(1):147-52

Department of Internal Medicine and Biocenter Oulu, University of Oulu, P.O. 5000, Finland.

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http://dx.doi.org/10.1016/s0021-9150(03)00091-1DOI Listing
May 2003

ATP-binding cassette transporter A1 locus is not a major determinant of HDL-C levels in a population at high risk for coronary heart disease.

Atherosclerosis 2003 Feb;166(2):285-90

Department of Internal Medicine and Biocenter Oulu, University of Oulu, P.O. BOX 5000, 90014, Oulu, Finland.

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http://dx.doi.org/10.1016/s0021-9150(02)00232-0DOI Listing
February 2003

Apolipoprotein E polymorphism affects carotid artery atherosclerosis in smoking hypertensive men.

J Hypertens 2002 Dec;20(12):2371-8

Department of Internal Medicine, University of Oulu, PO Box 5000, FIN-90014, Finland.

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http://dx.doi.org/10.1097/00004872-200212000-00015DOI Listing
December 2002

Effect of alcohol on lipids and lipoproteins in relation to atherosclerosis.

Crit Rev Clin Lab Sci 2002 Jun;39(3):225-83

Department of Internal Medicine, Biocenter Oulu, University of Oulu, Finland.

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http://dx.doi.org/10.1080/10408360290795529 DOI Listing
June 2002