Publications by authors named "Mark Trinder"

29Publications

Polygenic scores for dyslipidemia: the emerging genomic model of plasma lipoprotein trait inheritance.

Curr Opin Lipidol 2020 Dec 31;Publish Ahead of Print. Epub 2020 Dec 31.

Centre for Heart Lung Innovation, University of British Columbia Experimental Medicine Program, University of British Columbia Department of Medicine, University of British Columbia Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.

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December 2020

THE INTERPLAY BETWEEN TITIN, POLYGENIC RISK AND MODIFIABLE CARDIOVASCULAR RISK FACTORS IN ATRIAL FIBRILLATION.

Can J Cardiol 2020 Dec 26. Epub 2020 Dec 26.

Centre for Heart Lung Innovation, University of British Columbia, Vancouver, British Columbia, Canada; Experimental Medicine Program, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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December 2020

Inhibition of Cholesteryl Ester Transfer Protein Preserves High-Density Lipoprotein Cholesterol and Improves Survival in Sepsis.

Circulation 2020 Nov 24. Epub 2020 Nov 24.

Centre for Heart Lung Innovation, University of British Columbia, Vancouver, British Columbia, Canada; Experimental Medicine Program, University of British Columbia, Vancouver, British Columbia, Canada; Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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November 2020

Polygenic Contribution to Low-Density Lipoprotein Cholesterol Levels and Cardiovascular Risk in Monogenic Familial Hypercholesterolemia.

Circ Genom Precis Med 2020 Oct 13;13(5):515-523. Epub 2020 Aug 13.

Centre for Heart Lung Innovation (M.T., L.R.B.), University of British Columbia, Vancouver.

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October 2020

Clinical Utility of Lipoprotein(a) and LPA Genetic Risk Score in Risk Prediction of Incident Atherosclerotic Cardiovascular Disease.

JAMA Cardiol 2020 Oct 6. Epub 2020 Oct 6.

Program in Medical and Population Genetics and the Cardiovascular Disease Initiative, Broad Institute of Harvard, Cambridge, Massachusetts.

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October 2020

Genetic Confirmation of Monogenic Familial Hypercholesterolemia Advises a More Intensive Lipid-Lowering Approach-Reply.

JAMA Cardiol 2020 Sep 16. Epub 2020 Sep 16.

Centre for Heart Lung Innovation, University of British Columbia, Vancouver, British Columbia, Canada.

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September 2020

Ascertainment Bias in the Association Between Elevated Lipoprotein(a) and Familial Hypercholesterolemia.

J Am Coll Cardiol 2020 06;75(21):2682-2693

Centre for Heart Lung Innovation, University of British Columbia, Vancouver, British Columbia, Canada; Experimental Medicine Program, University of British Columbia, Vancouver, British Columbia, Canada; Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada; Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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June 2020

Association of Monogenic vs Polygenic Hypercholesterolemia With Risk of Atherosclerotic Cardiovascular Disease.

JAMA Cardiol 2020 04;5(4):390-399

Centre for Heart Lung Innovation, University of British Columbia, Vancouver, British Columbia, Canada.

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April 2020

Causal Inference for Genetically Determined Levels of High-Density Lipoprotein Cholesterol and Risk of Infectious Disease.

Arterioscler Thromb Vasc Biol 2020 01 7;40(1):267-278. Epub 2019 Nov 7.

From the Centre for Heart Lung Innovation (M.T., K.R.W., J.H.B., L.R.B.), associated with the University of British Columbia, Vancouver, Canada.

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January 2020

Estimating the Prevalence of Familial Hypercholesterolemia in Acute Coronary Syndrome: A Systematic Review and Meta-analysis.

Can J Cardiol 2019 10 24;35(10):1322-1331. Epub 2019 Jun 24.

Faculty of Medicine, University of British Columbia, Centre for Heart and Lung Innovation, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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October 2019

Risk of Premature Atherosclerotic Disease in Patients With Monogenic Versus Polygenic Familial Hypercholesterolemia.

J Am Coll Cardiol 2019 07;74(4):512-522

Centre for Heart Lung Innovation, University of British Columbia, Vancouver, British Columbia, Canada; Experimental Medicine Program, University of British Columbia, Vancouver, British Columbia, Canada; Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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July 2019

Natural selection on plasticity of thermal traits in a highly seasonal environment.

Evol Appl 2018 Dec 9;11(10):2004-2013. Epub 2018 Oct 9.

Department of Ecology and Evolutionary Biology University of California Santa Cruz California.

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December 2018

Immobilization of cadmium and lead by GR-1 mitigates apical-to-basolateral heavy metal translocation in a Caco-2 model of the intestinal epithelium.

Gut Microbes 2019 14;10(3):321-333. Epub 2018 Nov 14.

a Centre for Human Microbiome and Probiotic Research , Lawson Health Research Institute , London , Ontario , Canada.

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December 2019

Microbiota-Mediated Modulation of Organophosphate Insecticide Toxicity by Species-Dependent Interactions with Lactobacilli in a Drosophila melanogaster Insect Model.

Appl Environ Microbiol 2018 05 16;84(9). Epub 2018 Apr 16.

Centre for Human Microbiome and Probiotic Research, Lawson Health Research Institute, London, Ontario, Canada

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May 2018

Neonicotinoid-induced pathogen susceptibility is mitigated by Lactobacillus plantarum immune stimulation in a Drosophila melanogaster model.

Sci Rep 2017 06 2;7(1):2703. Epub 2017 Jun 2.

Canadian R&D Centre for Human Microbiome and Probiotic Research, Lawson Health Research Institute, London, N6A 4V2, Ontario, Canada.

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June 2017

as a High-Throughput Model for Host-Microbiota Interactions.

Front Microbiol 2017 28;8:751. Epub 2017 Apr 28.

Centre for Human Microbiome and Probiotic Research, Lawson Health Research Institute, St. Joseph's Health Care London, LondonON, Canada.

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April 2017

Probiotic Lactobacillus rhamnosus Reduces Organophosphate Pesticide Absorption and Toxicity to Drosophila melanogaster.

Appl Environ Microbiol 2016 10 30;82(20):6204-6213. Epub 2016 Sep 30.

Centre for Human Microbiome and Probiotic Research, Lawson Health Research Institute, London, Ontario, Canada Department of Microbiology and Immunology, The University of Western Ontario, London, Ontario, Canada Department of Surgery, St. Joseph's Health Care London, London, Ontario, Canada

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October 2016

Fibrin supports human fetal islet-epithelial cell differentiation via p70(s6k) and promotes vascular formation during transplantation.

Lab Invest 2015 Aug 1;95(8):925-36. Epub 2015 Jun 1.

1] Children's Health Research Institute, London, Ontario, Canada [2] Department of Physiology and Pharmacology, Western University, London, Ontario, Canada [3] Department of Medicine, Western University, London, Ontario, Canada.

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August 2015

Mapping seabird sensitivity to offshore wind farms.

PLoS One 2014 11;9(9):e106366. Epub 2014 Sep 11.

Marine Management Organisation, Newcastle, United Kingdom.

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May 2015

Fibrin, a scaffold material for islet transplantation and pancreatic endocrine tissue engineering.

Tissue Eng Part B Rev 2015 Feb 24;21(1):34-44. Epub 2014 Jul 24.

1 Children's Health Research Institute, London, Ontario, Canada .

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February 2015

Oil pollution and climate have wide-scale impacts on seabird demographics.

Ecol Lett 2005 Nov;8(11):1157-64

Department of Animal and Plant Sciences, University of Sheffield, Sheffield S10 2TN, UK Department of Zoology, South Parks Road, Oxford OX1 3PS, UK Wildfowl and Wetlands Trust, Slimbridge, Gloucestershire GL2 7BT, UK.

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November 2005