Publications by authors named "Mark T A Donoghue"

37Publications

Approach to the Treatment of a Patient with an Aggressive Pituitary Tumor.

J Clin Endocrinol Metab 2020 Dec;105(12)

Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, New York.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/clinem/dgaa649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566322PMC
December 2020

Paternally Expressed Imprinted Genes under Positive Darwinian Selection in Arabidopsis thaliana.

Mol Biol Evol 2019 06;36(6):1239-1253

Genetics & Biotechnology Lab, Plant & AgriBiosciences Research Centre (PABC), School of Natural Sciences, Ryan Institute, National University of Ireland Galway, Galway, Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/molbev/msz063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526901PMC
June 2019

Transgenerational effects of inter-ploidy cross direction on reproduction and F2 seed development of Arabidopsis thaliana F1 hybrid triploids.

Plant Reprod 2019 09 21;32(3):275-289. Epub 2019 Mar 21.

Genetics and Biotechnology Laboratory, Plant and AgriBiosciences Research Centre (PABC), Ryan Institute, National University of Ireland, Galway, H91 REW4, Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00497-019-00369-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675909PMC
September 2019

Widespread Selection for Oncogenic Mutant Allele Imbalance in Cancer.

Cancer Cell 2018 11 1;34(5):852-862.e4. Epub 2018 Nov 1.

Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2018.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234065PMC
November 2018

Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer.

Cancer Cell 2018 01;33(1):125-136.e3

Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Departments of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2017.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765991PMC
January 2018

AKT Inhibition in Solid Tumors With AKT1 Mutations.

J Clin Oncol 2017 Jul 10;35(20):2251-2259. Epub 2017 May 10.

David M. Hyman, Lillian M. Smyth, Mark T.A. Donoghue, Matthew T. Chang, Jonathan B. Reichel, Nancy Bouvier, S. Duygu Selcuklu, Tara E. Soumerai, Jean Torrisi, Joseph P. Erinjeri, Michael F. Berger, Sarat Chandarlapaty, David B. Solit, José Baselga, and Barry S. Taylor, Memorial Sloan Kettering Cancer Center; David B. Solit, Weill Cornell Medical College, Cornell University, New York, NY; J. Carl Barrett and Brian Dougherty, AstraZeneca, Waltham, MA; Helen Ambrose, Andrew Foxley, Justin P.O. Lindemann, Robert McEwen, Martin Pass, and Gaia Schiavon, AstraZeneca, Cambridge; Emma J. Dean, The Christie National Health Service Foundation, Manchester; Udai Banerji, Royal Marsden Hospital, London, United Kingdom; Shannon N. Westin, The University of Texas MD Anderson Cancer Center, Houston, TX; Philippe L. Bedard, Princess Margaret Cancer Centre, Toronto, Ontario, Canada; Hideaki Bando, National Cancer Center East Hospital, Kashiwa, Japan; Anthony B. El-Khoueiry, University of Southern California Norris Comprehensive Cancer Center; Alain Mita, Cedars-Sinai Medical Center, Los Angeles, CA; José A. Pérez-Fidalgo, Hospital Clinico de Valencia, Valencia, Spain; and Jan H.M. Schellens, Netherlands Cancer Institute, Amsterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2017.73.0143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501365PMC
July 2017

ALCAM is indirectly modulated by miR-125b in MCF7 cells.

Tumour Biol 2015 May 25;36(5):3511-20. Epub 2014 Dec 25.

Department of Biology, M.E.T.U., Dumlupınar Bulvarı No: 1, Cankaya, 06800, Ankara, Turkey.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s13277-014-2987-5
Publisher Site
http://dx.doi.org/10.1007/s13277-014-2987-5DOI Listing
May 2015

Selective methylation of histone H3 variant H3.1 regulates heterochromatin replication.

Science 2014 Mar;343(6176):1249-53

Howard Hughes Medical Institute-Gordon and Betty Moore Foundation, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1248357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049228PMC
March 2014

C(m)CGG methylation-independent parent-of-origin effects on genome-wide transcript levels in isogenic reciprocal F1 triploid plants.

DNA Res 2014 7;21(2):141-51. Epub 2013 Nov 7.

1Genetics and Biotechnology Laboratory, Plant and AgriBiosciences Research Centre (PABC), School of Natural Sciences, Aras de Brun, National University of Ireland,  Galway (NUI Galway), Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/dnares/dst046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989486PMC
April 2015

Reprogramming of DNA methylation in pollen guides epigenetic inheritance via small RNA.

Cell 2012 Sep 20;151(1):194-205. Epub 2012 Sep 20.

Howard Hughes Medical Institute-Gordon and Betty Moore Foundation, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, NY 11724, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2012.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697483PMC
September 2012

In Arabidopsis thaliana codon volatility scores reflect GC3 composition rather than selective pressure.

BMC Res Notes 2012 Jul 17;5:359. Epub 2012 Jul 17.

Bioinformatics and Molecular Evolution Group, School of Biotechnology,Dublin City University, Dublin 9, Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1756-0500-5-359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502101PMC
July 2012

Regulatory interplay between miR-21, JAG1 and 17beta-estradiol (E2) in breast cancer cells.

Biochem Biophys Res Commun 2012 Jun 19;423(2):234-9. Epub 2012 May 19.

Genetics and Biotechnology Lab, Centre for Chromosome Biology, School of Natural Sciences, National University of Ireland Galway, Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2012.05.074DOI Listing
June 2012

High-resolution analysis of parent-of-origin allelic expression in the Arabidopsis Endosperm.

PLoS Genet 2011 Jun 16;7(6):e1002126. Epub 2011 Jun 16.

Department of Biology and Zurich-Basel Plant Science Center, Swiss Federal Institute of Technology, Zurich, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1002126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116908PMC
June 2011

A phylogenetic approach to test for evidence of parental conflict or gene duplications associated with protein-encoding imprinted orthologous genes in placental mammals.

Mamm Genome 2010 Oct 8;21(9-10):486-98. Epub 2010 Oct 8.

Genetics and Biotechnology Lab, Department of Biochemistry and Biosciences Institute, University College Cork (UCC), Lee Maltings 2.10, Cork, Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00335-010-9283-5DOI Listing
October 2010

miR-21 as a key regulator of oncogenic processes.

Biochem Soc Trans 2009 Aug;37(Pt 4):918-25

Genetics and Biotechnology Laboratory, Biochemistry Department and Biosciences Institute, Lee Maltings 2.10, University College Cork, Cork, Ireland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/BST0370918DOI Listing
August 2009