Mark Rieder

Mark Rieder

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Mark Rieder

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Measures of exposure impact genetic association studies: an example in vitamin K levels and VKORC1.

Pac Symp Biocomput 2015 :161-70

Institute for Computational Biology, Department of Epidemiology and Biostatistics, Case Western Reserve University, Wolstein Research Building, 2103 Cornell Road, Suite 2527, Cleveland, OH 44106, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299921PMC
April 2016

High-throughput pairing of T cell receptor α and β sequences.

Sci Transl Med 2015 Aug;7(301):301ra131

Adaptive Biotechnologies, Seattle, WA 98102, USA. Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1126/scitranslmed.aac5624DOI Listing
August 2015

Exome Sequencing of Phenotypic Extremes Identifies CAV2 and TMC6 as Interacting Modifiers of Chronic Pseudomonas aeruginosa Infection in Cystic Fibrosis.

PLoS Genet 2015 Jun 5;11(6):e1005273. Epub 2015 Jun 5.

Department of Pediatrics, University of Washington, Seattle, Washington, United States of America; Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America; Division of Genetic Medicine, Seattle Children's Hospital, Seattle, Washington, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457883PMC
June 2015

Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol.

Authors:
Leslie A Lange Youna Hu He Zhang Chenyi Xue Ellen M Schmidt Zheng-Zheng Tang Chris Bizon Ethan M Lange Joshua D Smith Emily H Turner Goo Jun Hyun Min Kang Gina Peloso Paul Auer Kuo-Ping Li Jason Flannick Ji Zhang Christian Fuchsberger Kyle Gaulton Cecilia Lindgren Adam Locke Alisa Manning Xueling Sim Manuel A Rivas Oddgeir L Holmen Omri Gottesman Yingchang Lu Douglas Ruderfer Eli A Stahl Qing Duan Yun Li Peter Durda Shuo Jiao Aaron Isaacs Albert Hofman Joshua C Bis Adolfo Correa Michael E Griswold Johanna Jakobsdottir Albert V Smith Pamela J Schreiner Mary F Feitosa Qunyuan Zhang Jennifer E Huffman Jacy Crosby Christina L Wassel Ron Do Nora Franceschini Lisa W Martin Jennifer G Robinson Themistocles L Assimes David R Crosslin Elisabeth A Rosenthal Michael Tsai Mark J Rieder Deborah N Farlow Aaron R Folsom Thomas Lumley Ervin R Fox Christopher S Carlson Ulrike Peters Rebecca D Jackson Cornelia M van Duijn André G Uitterlinden Daniel Levy Jerome I Rotter Herman A Taylor Vilmundur Gudnason David S Siscovick Myriam Fornage Ingrid B Borecki Caroline Hayward Igor Rudan Y Eugene Chen Erwin P Bottinger Ruth J F Loos Pål Sætrom Kristian Hveem Michael Boehnke Leif Groop Mark McCarthy Thomas Meitinger Christie M Ballantyne Stacey B Gabriel Christopher J O'Donnell Wendy S Post Kari E North Alexander P Reiner Eric Boerwinkle Bruce M Psaty David Altshuler Sekar Kathiresan Dan-Yu Lin Gail P Jarvik L Adrienne Cupples Charles Kooperberg James G Wilson Deborah A Nickerson Goncalo R Abecasis Stephen S Rich Russell P Tracy Cristen J Willer

Am J Hum Genet 2014 Feb;94(2):233-45

Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2014.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928660PMC
February 2014

Exome sequencing reveals novel rare variants in the ryanodine receptor and calcium channel genes in malignant hyperthermia families.

Anesthesiology 2013 Nov;119(5):1054-65

* Assistant Professor, Department of Anesthesiology and Pain Medicine, † Professor, ‡ Associate Professor, § Biostatistician, Department of Medicine, Division of Medical Genetics, ‖ Graduate Student, # Research Professor, ** Research Scientist, †† Professor, Department of Genome Sciences, University of Washington, Seattle, Washington. ‡‡ Research Scientist, §§ Professor, Leeds Institute of Molecular Medicine, Leeds, United Kingdom.

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http://dx.doi.org/10.1097/ALN.0b013e3182a8a998DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115638PMC
November 2013

Ligand directed signaling differences between rodent and human κ-opioid receptors.

J Biol Chem 2012 Dec 19;287(50):41595-607. Epub 2012 Oct 19.

Department of Pharmacology, University of Washington, Seattle, Washington98195, USA.

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http://dx.doi.org/10.1074/jbc.M112.381368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516711PMC
December 2012

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.

Authors:
Zari Dastani Marie-France Hivert Nicholas Timpson John R B Perry Xin Yuan Robert A Scott Peter Henneman Iris M Heid Jorge R Kizer Leo-Pekka Lyytikäinen Christian Fuchsberger Toshiko Tanaka Andrew P Morris Kerrin Small Aaron Isaacs Marian Beekman Stefan Coassin Kurt Lohman Lu Qi Stavroula Kanoni James S Pankow Hae-Won Uh Ying Wu Aurelian Bidulescu Laura J Rasmussen-Torvik Celia M T Greenwood Martin Ladouceur Jonna Grimsby Alisa K Manning Ching-Ti Liu Jaspal Kooner Vincent E Mooser Peter Vollenweider Karen A Kapur John Chambers Nicholas J Wareham Claudia Langenberg Rune Frants Ko Willems-Vandijk Ben A Oostra Sara M Willems Claudia Lamina Thomas W Winkler Bruce M Psaty Russell P Tracy Jennifer Brody Ida Chen Jorma Viikari Mika Kähönen Peter P Pramstaller David M Evans Beate St Pourcain Naveed Sattar Andrew R Wood Stefania Bandinelli Olga D Carlson Josephine M Egan Stefan Böhringer Diana van Heemst Lyudmyla Kedenko Kati Kristiansson Marja-Liisa Nuotio Britt-Marie Loo Tamara Harris Melissa Garcia Alka Kanaya Margot Haun Norman Klopp H-Erich Wichmann Panos Deloukas Efi Katsareli David J Couper Bruce B Duncan Margreet Kloppenburg Linda S Adair Judith B Borja James G Wilson Solomon Musani Xiuqing Guo Toby Johnson Robert Semple Tanya M Teslovich Matthew A Allison Susan Redline Sarah G Buxbaum Karen L Mohlke Ingrid Meulenbelt Christie M Ballantyne George V Dedoussis Frank B Hu Yongmei Liu Bernhard Paulweber Timothy D Spector P Eline Slagboom Luigi Ferrucci Antti Jula Markus Perola Olli Raitakari Jose C Florez Veikko Salomaa Johan G Eriksson Timothy M Frayling Andrew A Hicks Terho Lehtimäki George Davey Smith David S Siscovick Florian Kronenberg Cornelia van Duijn Ruth J F Loos Dawn M Waterworth James B Meigs Josee Dupuis J Brent Richards Benjamin F Voight Laura J Scott Valgerdur Steinthorsdottir Christian Dina Ryan P Welch Eleftheria Zeggini Cornelia Huth Yurii S Aulchenko Gudmar Thorleifsson Laura J McCulloch Teresa Ferreira Harald Grallert Najaf Amin Guanming Wu Cristen J Willer Soumya Raychaudhuri Steve A McCarroll Oliver M Hofmann Ayellet V Segrè Mandy van Hoek Pau Navarro Kristin Ardlie Beverley Balkau Rafn Benediktsson Amanda J Bennett Roza Blagieva Eric Boerwinkle Lori L Bonnycastle Kristina Bengtsson Boström Bert Bravenboer Suzannah Bumpstead Noël P Burtt Guillaume Charpentier Peter S Chines Marilyn Cornelis Gabe Crawford Alex S F Doney Katherine S Elliott Amanda L Elliott Michael R Erdos Caroline S Fox Christopher S Franklin Martha Ganser Christian Gieger Niels Grarup Todd Green Simon Griffin Christopher J Groves Candace Guiducci Samy Hadjadj Neelam Hassanali Christian Herder Bo Isomaa Anne U Jackson Paul R V Johnson Torben Jørgensen Wen H L Kao Augustine Kong Peter Kraft Johanna Kuusisto Torsten Lauritzen Man Li Aloysius Lieverse Cecilia M Lindgren Valeriya Lyssenko Michel Marre Thomas Meitinger Kristian Midthjell Mario A Morken Narisu Narisu Peter Nilsson Katharine R Owen Felicity Payne Ann-Kristin Petersen Carl Platou Christine Proença Inga Prokopenko Wolfgang Rathmann N William Rayner Neil R Robertson Ghislain Rocheleau Michael Roden Michael J Sampson Richa Saxena Beverley M Shields Peter Shrader Gunnar Sigurdsson Thomas Sparsø Klaus Strassburger Heather M Stringham Qi Sun Amy J Swift Barbara Thorand Jean Tichet Tiinamaija Tuomi Rob M van Dam Timon W van Haeften Thijs van Herpt Jana V van Vliet-Ostaptchouk G Bragi Walters Michael N Weedon Cisca Wijmenga Jacqueline Witteman Richard N Bergman Stephane Cauchi Francis S Collins Anna L Gloyn Ulf Gyllensten Torben Hansen Winston A Hide Graham A Hitman Albert Hofman David J Hunter Kristian Hveem Markku Laakso Andrew D Morris Colin N A Palmer Igor Rudan Eric Sijbrands Lincoln D Stein Jaakko Tuomilehto Andre Uitterlinden Mark Walker Richard M Watanabe Goncalo R Abecasis Bernhard O Boehm Harry Campbell Mark J Daly Andrew T Hattersley Oluf Pedersen Inês Barroso Leif Groop Rob Sladek Unnur Thorsteinsdottir James F Wilson Thomas Illig Philippe Froguel Cornelia M van Duijn Kari Stefansson David Altshuler Michael Boehnke Mark I McCarthy Nicole Soranzo Eleanor Wheeler Nicole L Glazer Nabila Bouatia-Naji Reedik Mägi Joshua Randall Paul Elliott Denis Rybin Abbas Dehghan Jouke Jan Hottenga Kijoung Song Anuj Goel Taina Lajunen Alex Doney Christine Cavalcanti-Proença Meena Kumari Nicholas J Timpson Carina Zabena Erik Ingelsson Ping An Jeffrey O'Connell Jian'an Luan Amanda Elliott Steven A McCarroll Rosa Maria Roccasecca François Pattou Praveen Sethupathy Yavuz Ariyurek Philip Barter John P Beilby Yoav Ben-Shlomo Sven Bergmann Murielle Bochud Amélie Bonnefond Knut Borch-Johnsen Yvonne Böttcher Eric Brunner Suzannah J Bumpstead Yii-Der Ida Chen Peter Chines Robert Clarke Lachlan J M Coin Matthew N Cooper Laura Crisponi Ian N M Day Eco J C de Geus Jerome Delplanque Annette C Fedson Antje Fischer-Rosinsky Nita G Forouhi Maria Grazia Franzosi Pilar Galan Mark O Goodarzi Jürgen Graessler Scott Grundy Rhian Gwilliam Göran Hallmans Naomi Hammond Xijing Han Anna-Liisa Hartikainen Caroline Hayward Simon C Heath Serge Hercberg David R Hillman Aroon D Hingorani Jennie Hui Joe Hung Marika Kaakinen Jaakko Kaprio Y Antero Kesaniemi Mika Kivimaki Beatrice Knight Seppo Koskinen Peter Kovacs Kirsten Ohm Kyvik G Mark Lathrop Debbie A Lawlor Olivier Le Bacquer Cécile Lecoeur Yun Li Robert Mahley Massimo Mangino María Teresa Martínez-Larrad Jarred B McAteer Ruth McPherson Christa Meisinger David Melzer David Meyre Braxton D Mitchell Sutapa Mukherjee Silvia Naitza Matthew J Neville Marco Orrù Ruth Pakyz Giuseppe Paolisso Cristian Pattaro Daniel Pearson John F Peden Nancy L Pedersen Andreas F H Pfeiffer Irene Pichler Ozren Polasek Danielle Posthuma Simon C Potter Anneli Pouta Michael A Province Nigel W Rayner Kenneth Rice Samuli Ripatti Fernando Rivadeneira Olov Rolandsson Annelli Sandbaek Manjinder Sandhu Serena Sanna Avan Aihie Sayer Paul Scheet Udo Seedorf Stephen J Sharp Beverley Shields Gunnar Sigurðsson Eric J G Sijbrands Angela Silveira Laila Simpson Andrew Singleton Nicholas L Smith Ulla Sovio Amy Swift Holly Syddall Ann-Christine Syvänen Anke Tönjes André G Uitterlinden Ko Willems van Dijk Dhiraj Varma Sophie Visvikis-Siest Veronique Vitart Nicole Vogelzangs Gérard Waeber Peter J Wagner Andrew Walley Kim L Ward Hugh Watkins Sarah H Wild Gonneke Willemsen Jaqueline C M Witteman John W G Yarnell Diana Zelenika Björn Zethelius Guangju Zhai Jing Hua Zhao M Carola Zillikens Ingrid B Borecki Pierre Meneton Patrik K E Magnusson David M Nathan Gordon H Williams Kaisa Silander Stefan R Bornstein Peter Schwarz Joachim Spranger Fredrik Karpe Alan R Shuldiner Cyrus Cooper Manuel Serrano-Ríos Lars Lind Lyle J Palmer Frank B Hu Paul W Franks Shah Ebrahim Michael Marmot W H Linda Kao Peter Paul Pramstaller Alan F Wright Michael Stumvoll Anders Hamsten Thomas A Buchanan Timo T Valle Jerome I Rotter Brenda W J H Penninx Dorret I Boomsma Antonio Cao Angelo Scuteri David Schlessinger Manuela Uda Aimo Ruokonen Marjo-Riitta Jarvelin Leena Peltonen Vincent Mooser Robert Sladek Kiran Musunuru Albert V Smith Andrew C Edmondson Ioannis M Stylianou Masahiro Koseki James P Pirruccello Daniel I Chasman Christopher T Johansen Sigrid W Fouchier Gina M Peloso Maja Barbalic Sally L Ricketts Joshua C Bis Mary F Feitosa Marju Orho-Melander Olle Melander Xiaohui Li Mingyao Li Yoon Shin Cho Min Jin Go Young Jin Kim Jong-Young Lee Taesung Park Kyunga Kim Xueling Sim Rick Twee-Hee Ong Damien C Croteau-Chonka Leslie A Lange Joshua D Smith Andreas Ziegler Weihua Zhang Robert Y L Zee John B Whitfield John R Thompson Ida Surakka Tim D Spector Johannes H Smit Juha Sinisalo James Scott Juha Saharinen Chiara Sabatti Lynda M Rose Robert Roberts Mark Rieder Alex N Parker Guillaume Pare Christopher J O'Donnell Markku S Nieminen Deborah A Nickerson Grant W Montgomery Wendy McArdle David Masson Nicholas G Martin Fabio Marroni Gavin Lucas Robert Luben Marja-Liisa Lokki Guillaume Lettre Lenore J Launer Edward G Lakatta Reijo Laaksonen Kirsten O Kyvik Inke R König Kay-Tee Khaw Lee M Kaplan Åsa Johansson A Cecile J W Janssens Wilmar Igl G Kees Hovingh Christian Hengstenberg Aki S Havulinna Nicholas D Hastie Tamara B Harris Talin Haritunians Alistair S Hall Leif C Groop Elena Gonzalez Nelson B Freimer Jeanette Erdmann Kenechi G Ejebe Angela Döring Anna F Dominiczak Serkalem Demissie Panagiotis Deloukas Ulf de Faire Gabriel Crawford Yii-der I Chen Mark J Caulfield S Matthijs Boekholdt Themistocles L Assimes Thomas Quertermous Mark Seielstad Tien Y Wong E-Shyong Tai Alan B Feranil Christopher W Kuzawa Herman A Taylor Stacey B Gabriel Hilma Holm Vilmundur Gudnason Ronald M Krauss Jose M Ordovas Patricia B Munroe Jaspal S Kooner Alan R Tall Robert A Hegele John J P Kastelein Eric E Schadt David P Strachan Muredach P Reilly Nilesh J Samani Heribert Schunkert L Adrienne Cupples Manjinder S Sandhu Paul M Ridker Daniel J Rader Sekar Kathiresan

PLoS Genet 2012 29;8(3):e1002607. Epub 2012 Mar 29.

Department of Epidemiology, Biostatistics, and Occupational Health, Jewish General Hospital, Lady Davis Institute, McGill University, Montreal, Canada.

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http://dx.doi.org/10.1371/journal.pgen.1002607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315470PMC
September 2012

Evaluating pathogenicity of rare variants from dilated cardiomyopathy in the exome era.

Circ Cardiovasc Genet 2012 Apr 15;5(2):167-74. Epub 2012 Feb 15.

Cardiovascular Division, Department of Medicine and the Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

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http://dx.doi.org/10.1161/CIRCGENETICS.111.961805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332064PMC
April 2012

Detection of structural variants and indels within exome data.

Nat Methods 2011 Dec 18;9(2):176-8. Epub 2011 Dec 18.

Department of Genome Sciences, University of Washington School of Medicine, Seattle, Washington, USA.

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http://dx.doi.org/10.1038/nmeth.1810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269549PMC
December 2011

IGF1R variants associated with isolated single suture craniosynostosis.

Am J Med Genet A 2011 Jan;155A(1):91-7

Seattle Children's Hospital Craniofacial Center, University of Washington, 98195, USA.

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http://dx.doi.org/10.1002/ajmg.a.33781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059230PMC
January 2011

VKORC1 common variation and bone mineral density in the Third National Health and Nutrition Examination Survey.

PLoS One 2010 Dec 13;5(12):e15088. Epub 2010 Dec 13.

Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0015088PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001474PMC
December 2010

New genetic variant that might improve warfarin dose prediction in African Americans.

Br J Clin Pharmacol 2010 Sep;70(3):393-9

Center for Clinical Epidemiology and Biostatistics, Department of Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Pittsburgh, PA 19104-6021, USA.

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http://dx.doi.org/10.1111/j.1365-2125.2010.03709.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949912PMC
September 2010

Biological, clinical and population relevance of 95 loci for blood lipids.

Authors:
Tanya M Teslovich Kiran Musunuru Albert V Smith Andrew C Edmondson Ioannis M Stylianou Masahiro Koseki James P Pirruccello Samuli Ripatti Daniel I Chasman Cristen J Willer Christopher T Johansen Sigrid W Fouchier Aaron Isaacs Gina M Peloso Maja Barbalic Sally L Ricketts Joshua C Bis Yurii S Aulchenko Gudmar Thorleifsson Mary F Feitosa John Chambers Marju Orho-Melander Olle Melander Toby Johnson Xiaohui Li Xiuqing Guo Mingyao Li Yoon Shin Cho Min Jin Go Young Jin Kim Jong-Young Lee Taesung Park Kyunga Kim Xueling Sim Rick Twee-Hee Ong Damien C Croteau-Chonka Leslie A Lange Joshua D Smith Kijoung Song Jing Hua Zhao Xin Yuan Jian'an Luan Claudia Lamina Andreas Ziegler Weihua Zhang Robert Y L Zee Alan F Wright Jacqueline C M Witteman James F Wilson Gonneke Willemsen H-Erich Wichmann John B Whitfield Dawn M Waterworth Nicholas J Wareham Gérard Waeber Peter Vollenweider Benjamin F Voight Veronique Vitart Andre G Uitterlinden Manuela Uda Jaakko Tuomilehto John R Thompson Toshiko Tanaka Ida Surakka Heather M Stringham Tim D Spector Nicole Soranzo Johannes H Smit Juha Sinisalo Kaisa Silander Eric J G Sijbrands Angelo Scuteri James Scott David Schlessinger Serena Sanna Veikko Salomaa Juha Saharinen Chiara Sabatti Aimo Ruokonen Igor Rudan Lynda M Rose Robert Roberts Mark Rieder Bruce M Psaty Peter P Pramstaller Irene Pichler Markus Perola Brenda W J H Penninx Nancy L Pedersen Cristian Pattaro Alex N Parker Guillaume Pare Ben A Oostra Christopher J O'Donnell Markku S Nieminen Deborah A Nickerson Grant W Montgomery Thomas Meitinger Ruth McPherson Mark I McCarthy Wendy McArdle David Masson Nicholas G Martin Fabio Marroni Massimo Mangino Patrik K E Magnusson Gavin Lucas Robert Luben Ruth J F Loos Marja-Liisa Lokki Guillaume Lettre Claudia Langenberg Lenore J Launer Edward G Lakatta Reijo Laaksonen Kirsten O Kyvik Florian Kronenberg Inke R König Kay-Tee Khaw Jaakko Kaprio Lee M Kaplan Asa Johansson Marjo-Riitta Jarvelin A Cecile J W Janssens Erik Ingelsson Wilmar Igl G Kees Hovingh Jouke-Jan Hottenga Albert Hofman Andrew A Hicks Christian Hengstenberg Iris M Heid Caroline Hayward Aki S Havulinna Nicholas D Hastie Tamara B Harris Talin Haritunians Alistair S Hall Ulf Gyllensten Candace Guiducci Leif C Groop Elena Gonzalez Christian Gieger Nelson B Freimer Luigi Ferrucci Jeanette Erdmann Paul Elliott Kenechi G Ejebe Angela Döring Anna F Dominiczak Serkalem Demissie Panagiotis Deloukas Eco J C de Geus Ulf de Faire Gabriel Crawford Francis S Collins Yii-der I Chen Mark J Caulfield Harry Campbell Noel P Burtt Lori L Bonnycastle Dorret I Boomsma S Matthijs Boekholdt Richard N Bergman Inês Barroso Stefania Bandinelli Christie M Ballantyne Themistocles L Assimes Thomas Quertermous David Altshuler Mark Seielstad Tien Y Wong E-Shyong Tai Alan B Feranil Christopher W Kuzawa Linda S Adair Herman A Taylor Ingrid B Borecki Stacey B Gabriel James G Wilson Hilma Holm Unnur Thorsteinsdottir Vilmundur Gudnason Ronald M Krauss Karen L Mohlke Jose M Ordovas Patricia B Munroe Jaspal S Kooner Alan R Tall Robert A Hegele John J P Kastelein Eric E Schadt Jerome I Rotter Eric Boerwinkle David P Strachan Vincent Mooser Kari Stefansson Muredach P Reilly Nilesh J Samani Heribert Schunkert L Adrienne Cupples Manjinder S Sandhu Paul M Ridker Daniel J Rader Cornelia M van Duijn Leena Peltonen Gonçalo R Abecasis Michael Boehnke Sekar Kathiresan

Nature 2010 Aug;466(7307):707-13

Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1038/nature09270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039276PMC
August 2010

Combined influence of LDLR and HMGCR sequence variation on lipid-lowering response to simvastatin.

Arterioscler Thromb Vasc Biol 2010 Jul 22;30(7):1485-92. Epub 2010 Apr 22.

Children's Hospital Oakland Research Institute, 5700 Martin Luther King Jr. Way, Oakland, CA 94609, USA.

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http://dx.doi.org/10.1161/ATVBAHA.110.203273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909117PMC
July 2010

Human liver expression of CYP2C8: gender, age, and genotype effects.

Drug Metab Dispos 2010 Jun 26;38(6):889-93. Epub 2010 Feb 26.

Departments of Medicinal Chemistry, University of Washington, Seattle, WA 98195-7610, USA.

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http://dx.doi.org/10.1124/dmd.109.031542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879956PMC
June 2010

Single nucleotide polymorphism discovery in TBX1 in individuals with and without 22q11.2 deletion syndrome.

Birth Defects Res A Clin Mol Teratol 2010 Jan;88(1):54-63

Department of Pediatrics, Division of Craniofacial Medicine, University of Washington and Seattle Children's Hospital, Seattle, Washington 98105-5371, USA.

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http://dx.doi.org/10.1002/bdra.20604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535433PMC
January 2010

LPA and PLG sequence variation and kringle IV-2 copy number in two populations.

Hum Hered 2008 9;66(4):199-209. Epub 2008 Jul 9.

Department of Molecular Physiology and Biophysics, Center for Human Genetics Research, Vanderbilt University, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1159/000143403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861532PMC
October 2008

VKORC1 polymorphisms, haplotypes and haplotype groups on warfarin dose among African-Americans and European-Americans.

Pharmacogenomics 2008 Oct;9(10):1445-58

Department of Neurology, University of Alabama at Birmingham, 1719 6th Avenue South, CIRC-312, Birmingham AL 35294-0021, USA.

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http://dx.doi.org/10.2217/14622416.9.10.1445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586955PMC
October 2008

An analysis of the relative effects of VKORC1 and CYP2C9 variants on anticoagulation related outcomes in warfarin-treated patients.

Thromb Haemost 2008 Aug;100(2):229-39

University of Washington, Department of Pharmacy, Seattle, WA 98195, USA.

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August 2008

Estimating coverage and power for genetic association studies using near-complete variation data.

Nat Genet 2008 Jul 22;40(7):841-3. Epub 2008 Jun 22.

Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA.

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http://www.nature.com/articles/ng.180
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http://dx.doi.org/10.1038/ng.180DOI Listing
July 2008

Novel CYP2C9 promoter variants and assessment of their impact on gene expression.

Mol Pharmacol 2008 Jun 29;73(6):1751-60. Epub 2008 Feb 29.

Department of Pediatrics, Medical College of Wisconsin, Milwaukee WI 53226, USA.

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http://dx.doi.org/10.1124/mol.107.044149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413059PMC
June 2008

The environmental genome project: reference polymorphisms for drug metabolism genes and genome-wide association studies.

Drug Metab Rev 2008 ;40(2):241-61

Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA.

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http://dx.doi.org/10.1080/03602530801952880DOI Listing
June 2008

Sequence variation in the human transcription factor gene POU5F1.

BMC Genet 2008 Feb 6;9:15. Epub 2008 Feb 6.

University of California, Los Angeles, Division of Cancer Prevention and Control Research, School of Public Health and Jonsson Comprehensive Cancer Center, Los Angeles, CA, 90095-6900, USA.

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http://bmcgenet.biomedcentral.com/articles/10.1186/1471-2156
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http://dx.doi.org/10.1186/1471-2156-9-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275747PMC
February 2008

Functional polymorphism in human CYP4F2 decreases 20-HETE production.

Physiol Genomics 2007 Jun 6;30(1):74-81. Epub 2007 Mar 6.

Department of Physiology & Biophysics, University of Mississippi Medical Center, Jackson, Mississippi 39216-4505, USA.

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http://www.physiology.org/doi/10.1152/physiolgenomics.00003.
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http://dx.doi.org/10.1152/physiolgenomics.00003.2007DOI Listing
June 2007

Identifying the genotype behind the phenotype: a role model found in VKORC1 and its association with warfarin dosing.

Pharmacogenomics 2007 May;8(5):487-96

Vanderbilt University, Center for Human Genetics Research, 519 Light Hall, Nashville, TN 37232, USA.

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https://www.futuremedicine.com/doi/10.2217/14622416.8.5.487
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http://dx.doi.org/10.2217/14622416.8.5.487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112050PMC
May 2007

Allele frequency matching between SNPs reveals an excess of linkage disequilibrium in genic regions of the human genome.

PLoS Genet 2006 Sep 25;2(9):e142. Epub 2006 Jul 25.

Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.0020142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1560400PMC
September 2006

Efficient selection of tagging single-nucleotide polymorphisms in multiple populations.

Hum Genet 2006 Aug 6;120(1):58-68. Epub 2006 May 6.

Department of Genome Sciences, University of Washington, Box 357730, Seattle, WA 98195, USA.

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http://link.springer.com/10.1007/s00439-006-0182-5
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http://dx.doi.org/10.1007/s00439-006-0182-5DOI Listing
August 2006

Allelic spectrum of the natural variation in CRP.

Hum Genet 2006 Jun 21;119(5):496-504. Epub 2006 Mar 21.

Department of Genome Sciences, University of Washington, 1705 NE Pacific, Seattle, WA 98195-7730, USA.

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http://link.springer.com/10.1007/s00439-006-0160-y
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http://dx.doi.org/10.1007/s00439-006-0160-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1449912PMC
June 2006

Direct detection of null alleles in SNP genotyping data.

Hum Mol Genet 2006 Jun 27;15(12):1931-7. Epub 2006 Apr 27.

Department of Genome Sciences, University of Washington, Seattle, WA 98195-7730, USA.

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http://dx.doi.org/10.1093/hmg/ddl115DOI Listing
June 2006

Common genetic variation in the prothrombin gene, hormone therapy, and incident nonfatal myocardial infarction in postmenopausal women.

Am J Epidemiol 2006 Apr 8;163(7):600-7. Epub 2006 Feb 8.

Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA 98101, USA.

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http://dx.doi.org/10.1093/aje/kwj092DOI Listing
April 2006

High-throughput genotyping of intermediate-size structural variation.

Hum Mol Genet 2006 Apr 23;15(7):1159-67. Epub 2006 Feb 23.

Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1093/hmg/ddl031DOI Listing
April 2006

Genomic regions exhibiting positive selection identified from dense genotype data.

Genome Res 2005 Nov;15(11):1553-65

Department of Genome Sciences, University of Washington, Seattle, Washington 98195-7730, USA.

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http://dx.doi.org/10.1101/gr.4326505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1310643PMC
November 2005

In-vitro and in-vivo effects of the CYP2C9*11 polymorphism on warfarin metabolism and dose.

Pharmacogenet Genomics 2005 Jul;15(7):475-81

Department of Medicinal Chemistry, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1097/01.fpc.0000162005.80857.98DOI Listing
July 2005

Identification of persistently altered gene expression in the kidney after functional recovery from ischemic acute renal failure.

Am J Physiol Renal Physiol 2005 May 4;288(5):F953-63. Epub 2005 Jan 4.

Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.

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http://dx.doi.org/10.1152/ajprenal.00329.2004DOI Listing
May 2005

CYP2C9 haplotype structure in European American warfarin patients and association with clinical outcomes.

Clin Pharmacol Ther 2005 May;77(5):353-64

Department of Pharmacy, Environmental Health, Genome Sciences, and Medicinal Chemistry, University of Washington, Seattle, USA.

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http://dx.doi.org/10.1016/j.clpt.2005.01.019DOI Listing
May 2005

Comprehensive identification and characterization of diallelic insertion-deletion polymorphisms in 330 human candidate genes.

Hum Mol Genet 2005 Jan 3;14(1):59-69. Epub 2004 Nov 3.

Department of Bioengineering, University of Washington, Seattle, WA 98195-7730, USA.

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http://dx.doi.org/10.1093/hmg/ddi006DOI Listing
January 2005

Sequence-based linkage analysis.

Am J Hum Genet 2004 Oct 25;75(4):647-53. Epub 2004 Aug 25.

Division of Human Biology, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA 98109-1024, USA.

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http://dx.doi.org/10.1086/424888DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182051PMC
October 2004

Population history and natural selection shape patterns of genetic variation in 132 genes.

PLoS Biol 2004 Oct 7;2(10):e286. Epub 2004 Sep 7.

Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

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http://dx.doi.org/10.1371/journal.pbio.0020286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC515367PMC
October 2004

Evidence for substantial fine-scale variation in recombination rates across the human genome.

Nat Genet 2004 Jul 6;36(7):700-6. Epub 2004 Jun 6.

Department of Genome Sciences, University of Washington, Box 354322, Seattle, Washington 98195, USA.

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http://dx.doi.org/10.1038/ng1376DOI Listing
July 2004

An association study of angiotensinogen polymorphisms with serum level and hypertension in an African-American population.

J Hypertens 2003 Oct;21(10):1847-52

Department of Preventive Medicine and Epidemiology, Loyola Stritch School of Medicine, Maywood, Illinois 60153, USA.

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http://dx.doi.org/10.1097/00004872-200310000-00011DOI Listing
October 2003

Paraoxonase activity, but not haplotype utilizing the linkage disequilibrium structure, predicts vascular disease.

Arterioscler Thromb Vasc Biol 2003 Aug 12;23(8):1465-71. Epub 2003 Jun 12.

Department of Medicine, Division of Medical Genetics, University of Washington, Seattle, Wash, USA.

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http://dx.doi.org/10.1161/01.ATV.0000081635.96290.D3DOI Listing
August 2003

Novel paraoxonase (PON1) nonsense and missense mutations predicted by functional genomic assay of PON1 status.

Pharmacogenetics 2003 May;13(5):291-5

Department of Medicine, Division of Medical Genetics, The University of Washington, Seattle, Washington 98195-7720, USA.

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http://dx.doi.org/10.1097/00008571-200305000-00009DOI Listing
May 2003

Additional SNPs and linkage-disequilibrium analyses are necessary for whole-genome association studies in humans.

Nat Genet 2003 Apr 24;33(4):518-21. Epub 2003 Mar 24.

Department of Genome Sciences, University of Washington, 1705 NE Pacific, Seattle, Washington 98195-7730, USA.

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http://dx.doi.org/10.1038/ng1128DOI Listing
April 2003