Mark R Toshner

Mark R Toshner

UNVERIFIED PROFILE

Are you Mark R Toshner?   Register this Author

Register author
Mark R Toshner

Mark R Toshner

Publications by authors named "Mark R Toshner"

Are you Mark R Toshner?   Register this Author

19Publications

624Reads

31Profile Views

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.

Authors:
Christopher J Rhodes Ken Batai Marta Bleda Matthias Haimel Laura Southgate Marine Germain Michael W Pauciulo Charaka Hadinnapola Jurjan Aman Barbara Girerd Amit Arora Jo Knight Ken B Hanscombe Jason H Karnes Marika Kaakinen Henning Gall Anna Ulrich Lars Harbaum Inês Cebola Jorge Ferrer Katie Lutz Emilia M Swietlik Ferhaan Ahmad Philippe Amouyel Stephen L Archer Rahul Argula Eric D Austin David Badesch Sahil Bakshi Christopher Barnett Raymond Benza Nitin Bhatt Harm J Bogaard Charles D Burger Murali Chakinala Colin Church John G Coghlan Robin Condliffe Paul A Corris Cesare Danesino Stéphanie Debette C Gregory Elliott Jean Elwing Melanie Eyries Terry Fortin Andre Franke Robert P Frantz Adaani Frost Joe G N Garcia Stefano Ghio Hossein-Ardeschir Ghofrani J Simon R Gibbs John Harley Hua He Nicholas S Hill Russel Hirsch Arjan C Houweling Luke S Howard Dunbar Ivy David G Kiely James Klinger Gabor Kovacs Tim Lahm Matthias Laudes Rajiv D Machado Robert V MacKenzie Ross Keith Marsolo Lisa J Martin Shahin Moledina David Montani Steven D Nathan Michael Newnham Andrea Olschewski Horst Olschewski Ronald J Oudiz Willem H Ouwehand Andrew J Peacock Joanna Pepke-Zaba Zia Rehman Ivan Robbins Dan M Roden Erika B Rosenzweig Ghulam Saydain Laura Scelsi Robert Schilz Werner Seeger Christian M Shaffer Robert W Simms Marc Simon Olivier Sitbon Jay Suntharalingam Haiyang Tang Alexander Y Tchourbanov Thenappan Thenappan Fernando Torres Mark R Toshner Carmen M Treacy Anton Vonk Noordegraaf Quinten Waisfisz Anna K Walsworth Robert E Walter John Wharton R James White Jeffrey Wilt Stephen J Wort Delphine Yung Allan Lawrie Marc Humbert Florent Soubrier David-Alexandre Trégouët Inga Prokopenko Richard Kittles Stefan Gräf William C Nichols Richard C Trembath Ankit A Desai Nicholas W Morrell Martin R Wilkins

Lancet Respir Med 2019 Mar 5;7(3):227-238. Epub 2018 Dec 5.

Department of Medicine, Imperial College London, London, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2213-2600(18)30409-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391516PMC
March 2019

Plasma Metabolomics Implicates Modified Transfer RNAs and Altered Bioenergetics in the Outcomes of Pulmonary Arterial Hypertension.

Circulation 2017 01 21;135(5):460-475. Epub 2016 Nov 21.

From the Department of Medicine, Imperial College London, Hammersmith Campus, United Kingdom (C.J.R., P.G., J.W., K.C.R.-A., G.W., M.R.W.); Department of Medicine, University of Cambridge School of Clinical Medicine, United Kingdom (C.H., M.B., M.H., M.R.T., S.G., N.W.M.); Cardiology Department, Royal Free Hospital, London, United Kingdom (G.C.); Institute of Cellular Medicine, Newcastle University and the Newcastle Upon Tyne Hospitals NHS Foundation Trust, United Kingdom (P.A.C.); National Pulmonary Hypertension Service, Imperial College Healthcare NHS Trust, Hammersmith Hospital, London, United Kingdom (L.S.H., J.S.R.G.); National Heart and Lung Institute, Imperial College London, Hammersmith Campus, United Kingdom (L.S.H., J.S.R.G.); Sheffield Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, United Kingdom (D.G.K.); Department of Infection, Immunity & Cardiovascular Disease, University of Sheffield, United Kingdom (D.G.K., A.L.); Scottish Pulmonary Vascular Unit, Golden Jubilee National Hospital, Glasgow, United Kingdom (A.J.P.); Pulmonary Vascular Disease Unit, Papworth Hospital, Cambridge, United Kingdom (J.P.Z., M.R.T.); Pulmonary Hypertension Service, Royal Brompton Hospital, London, United Kingdom (S.J.W.); and Department of Haematology, University of Cambridge, United Kingdom (S.G.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287439PMC
January 2017

The pulmonary endothelium in acute respiratory distress syndrome: insights and therapeutic opportunities.

Thorax 2016 May 11;71(5):462-73. Epub 2016 Mar 11.

Leukocyte Biology Section, National Heart & Lung Institute, Imperial College, London, UK Frederick Meijer Heart & Vascular Institute, Spectrum Health, Grand Rapids, Michigan, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/thoraxjnl-2015-207461DOI Listing
May 2016

The lysosomal inhibitor, chloroquine, increases cell surface BMPR-II levels and restores BMP9 signalling in endothelial cells harbouring BMPR-II mutations.

Hum Mol Genet 2013 Sep 12;22(18):3667-79. Epub 2013 May 12.

Division of Respiratory Medicine, Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke's and Papworth Hospitals, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddt216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749859PMC
September 2013

Decreased time constant of the pulmonary circulation in chronic thromboembolic pulmonary hypertension.

Am J Physiol Heart Circ Physiol 2013 Jul 17;305(2):H259-64. Epub 2013 May 17.

Pulmonary Vascular Disease Unit, Papworth Hospital, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpheart.00128.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726952PMC
July 2013

Unexplained iron deficiency in idiopathic and heritable pulmonary arterial hypertension.

Thorax 2011 Apr 5;66(4):326-32. Epub 2011 Feb 5.

Pulmonary Vascular Diseases Unit, Papworth Hospital NHS Trust, Papworth Everard, Cambridgeshire CB3 8RE, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/thx.2010.147272DOI Listing
April 2011

NT-proBNP does not rise on acute ascent to high altitude.

High Alt Med Biol 2008 ;9(4):307-10

Pulmonary Vascular Diseases Unit, Papworth Hospital, Cambridgeshire, England, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/ham.2008.1054DOI Listing
April 2009

Long-term use of sildenafil in inoperable chronic thromboembolic pulmonary hypertension.

Chest 2008 Aug 8;134(2):229-236. Epub 2008 Feb 8.

Pulmonary Vascular Diseases Unit, Pulmonary Vascular Diseases Unit, Papworth Hospital, Cambridgeshire. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1378/chest.07-2681DOI Listing
August 2008