Mark Pritchard

Mark Pritchard

UNVERIFIED PROFILE

Are you Mark Pritchard?   Register this Author

Register author
Mark Pritchard

Mark Pritchard

Publications by authors named "Mark Pritchard"

Are you Mark Pritchard?   Register this Author

66Publications

-Reads

Relationship of anxiety with joint pain and its management: A population survey.

Musculoskeletal Care 2018 Sep 20;16(3):353-362. Epub 2018 Apr 20.

Research Institute for Primary Care and Health Sciences, Keele University, Keele, Staffordshire, ST5 5BG, UK.

View Article
September 2018

In Reply to Habr-Gama et al.

Int J Radiat Oncol Biol Phys 2018 Jul;101(3):743-744

The Royal Liverpool and Broadgreen University Hospital NHS Trust, Liverpool, United Kingdom; Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.

View Article
July 2018

The Nrf2 inhibitor brusatol is a potent antitumour agent in an orthotopic mouse model of colorectal cancer.

Oncotarget 2018 Jun 5;9(43):27104-27116. Epub 2018 Jun 5.

MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.

View Article
June 2018

Dose Escalation Using Contact X-ray Brachytherapy After External Beam Radiotherapy as Nonsurgical Treatment Option for Rectal Cancer: Outcomes From a Single-Center Experience.

Int J Radiat Oncol Biol Phys 2018 Mar 20;100(3):565-573. Epub 2017 Oct 20.

Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom; The Royal Liverpool and Broadgreen University Hospital National Health Service Trust, Liverpool, United Kingdom.

View Article
March 2018

Cost-effectiveness of enhanced recovery in hip and knee replacement: a systematic review protocol.

BMJ Open 2018 03 14;8(3):e019740. Epub 2018 Mar 14.

Health Economics Research Centre, Nuffield Department of Population Health, Medical Sciences Division, University of Oxford, Oxford, UK.

View Article
March 2018

Mice lacking NF-κB1 exhibit marked DNA damage responses and more severe gastric pathology in response to intraperitoneal tamoxifen administration.

Cell Death Dis 2017 07 20;8(7):e2939. Epub 2017 Jul 20.

Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, The Henry Wellcome Laboratory, Liverpool, UK.

View Article
July 2017

Netazepide, a gastrin/cholecystokinin-2 receptor antagonist, can eradicate gastric neuroendocrine tumours in patients with autoimmune chronic atrophic gastritis.

Br J Clin Pharmacol 2017 03 21;83(3):466-475. Epub 2016 Nov 21.

Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool, L69 3GE, UK.

View Article
March 2017

Helicobacter pylori-induced gastric pathology: insights from in vivo and ex vivo models.

Dis Model Mech 2017 02;10(2):89-104

Gastroenterology Research Unit, Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool L69 3GE, UK

View Article
February 2017

Hexane Extracts of Inhibit the Development of Gastric Preneoplasia in Infected INS-Gas Mice.

Front Pharmacol 2017 27;8:92. Epub 2017 Feb 27.

Gastroenterology Research Unit, Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool Liverpool, UK.

View Article
February 2017

Potential clinical indications for a CCK receptor antagonist.

Curr Opin Pharmacol 2016 12 3;31:68-75. Epub 2016 Oct 3.

Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Crown Street, Liverpool L69 3GE, UK. Electronic address:

View Article
December 2016

A knockin mouse model for human ATP4aR703C mutation identified in familial gastric neuroendocrine tumors recapitulates the premalignant condition of the human disease and suggests new therapeutic strategies.

Dis Model Mech 2016 09 4;9(9):975-84. Epub 2016 Aug 4.

Human Genetics Group, Spanish National Cancer Research Center (CNIO), Madrid 28029, Spain Spanish Center for Biomedical Network Research on Rare Diseases (CIBERER), Madrid 28029, Spain

View Article
September 2016

Gastrin-induced miR-222 promotes gastric tumor development by suppressing p27kip1.

Oncotarget 2016 07;7(29):45462-45478

Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.

View Article
July 2016

Importance of the alternative NF-κB activation pathway in inflammation-associated gastrointestinal carcinogenesis.

Am J Physiol Gastrointest Liver Physiol 2016 06 21;310(11):G1081-90. Epub 2016 Apr 21.

Gastroenterology Research Unit, Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom

View Article
June 2016

Intestinal Preparation Techniques for Histological Analysis in the Mouse.

Curr Protoc Mouse Biol 2016 Jun 1;6(2):148-68. Epub 2016 Jun 1.

Gastroenterology Research Unit, Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.

View Article
June 2016

Helicobacter pylori, HIV and Gastric Hypochlorhydria in the Malawian Population.

PLoS One 2015 5;10(8):e0132043. Epub 2015 Aug 5.

Malawi-Liverpool-Wellcome Trust Clinical Research Programme, PO Box 30096, Blantyre 3, Malawi; Department of Clinical Infection, Microbiology and Immunology, Institute of Infection and Global Health, University of Liverpool, Liverpool, United Kingdom; Department of Gastroenterology, Royal Liverpool University Hospital, Liverpool, United Kingdom.

View Article
May 2016

Long-term results following polydioxanone sling fixation technique in unstable lateral clavicle fracture.

Eur J Orthop Surg Traumatol 2016 Apr 21;26(3):271-6. Epub 2016 Jan 21.

The Shoulder Unit, Department of Trauma and Orthopaedics, Morriston Hospital, Heol Maes Eglwys, Morriston, Swansea, SA6 6NL, UK.

View Article
April 2016

PAK1 modulates a PPARγ/NF-κB cascade in intestinal inflammation.

Biochim Biophys Acta 2015 Oct 31;1853(10 Pt A):2349-60. Epub 2015 May 31.

Medical University of Vienna, Department of Internal Medicine III, Division of Gastroenterology and Hepatology, Christian Doppler Laboratory for Molecular Cancer Chemoprevention, Vienna, Austria. Electronic address:

View Article
October 2015

Gastrin stimulates MMP-1 expression in gastric epithelial cells: putative role in gastric epithelial cell migration.

Am J Physiol Gastrointest Liver Physiol 2015 Jul 14;309(2):G78-86. Epub 2015 May 14.

Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom; and

View Article
July 2015

Methicillin-resistant Staphylococcus aureus infection of the subacromial bursa: an unusual complication following subacromial corticosteroid injection (a report of two cases).

Shoulder Elbow 2015 Jul 30;7(3):182-6. Epub 2014 Oct 30.

Department of Trauma and Orthopaedics, Morriston Hospital, Heol Maes Eglwys, Morriston, Swansea, UK.

View Article
July 2015

Murine Models of Helicobacter (pylori or felis)-associated Gastric Cancer.

Curr Protoc Pharmacol 2015 Jun 1;69:14.34.1-35. Epub 2015 Jun 1.

Department of Cellular and Molecular Physiology, Gastroenterology Research Unit, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.

View Article
June 2015

Outcomes in children with protracted bacterial bronchitis confirmed by bronchoscopy.

Arch Dis Child 2015 Jan 9;100(1):112. Epub 2014 Sep 9.

Academic Department of Child Health, University Hospital of North Staffordshire, Stoke-on-Trent, UK Institute for Science and Technology in Medicine, Keele University, Guy Hilton Research Centre, Stoke-on-Trent, UK.

View Article
January 2015

Peanut agglutinin appearance in the blood circulation after peanut ingestion mimics the action of endogenous galectin-3 to promote metastasis by interaction with cancer-associated MUC1.

Carcinogenesis 2014 Dec 17;35(12):2815-21. Epub 2014 Oct 17.

Department of Gastroenterology, Institute of Translational Medicine, University of Liverpool, Liverpool L69 3GE, UK andDepartment of Pharmacology, Shandong University, Shandong 250012, China

View Article
December 2014

Netazepide, a gastrin receptor antagonist, normalises tumour biomarkers and causes regression of type 1 gastric neuroendocrine tumours in a nonrandomised trial of patients with chronic atrophic gastritis.

PLoS One 2013 1;8(10):e76462. Epub 2013 Oct 1.

Department of Gastroenterology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom ; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.

View Article
July 2014

Incidence of symptomatic venous thrombo-embolism following shoulder surgery.

Int Orthop 2014 Jul 2;38(7):1415-8. Epub 2014 Apr 2.

Nevill Hall Hospital, Abergavenny, Wales, UK,

View Article
July 2014

The association of a panel of biomarkers with the presence and severity of carcinoid heart disease: a cross-sectional study.

PLoS One 2013 12;8(9):e73679. Epub 2013 Sep 12.

Neuroendocrine Tumour Group, University Hospital Aintree, Liverpool, Merseyside, United Kingdom ; Department of Obesity and Endocrinology, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool Merseyside, United Kingdom.

View Article
April 2014

Effects of EGFR Inhibitor on Helicobacter pylori Induced Gastric Epithelial Pathology in Vivo.

Pathogens 2013 Oct 14;2(4):571-90. Epub 2013 Oct 14.

Leeds Institute of Molecular Medicine, St. James's University Hospital, Leeds LS9 7TF, UK.

View Article
October 2013

Proteomic profiling of a mouse model of acute intestinal Apc deletion leads to identification of potential novel biomarkers of human colorectal cancer (CRC).

Biochem Biophys Res Commun 2013 Oct 31;440(3):364-70. Epub 2013 Aug 31.

Department of Gastroenterology, Institute of Translational Medicine, The University of Liverpool, Crown Street, Liverpool L69 3GE, UK. Electronic address:

View Article
October 2013

Progastrin-induced secretion of insulin-like growth factor 2 from colonic myofibroblasts stimulates colonic epithelial proliferation in mice.

Gastroenterology 2013 Jul 19;145(1):197-208.e3. Epub 2013 Mar 19.

Department of Gastroenterology, Institute of Translational Medicine, University of Liverpool, Liverpool, England. Electronic address:

View Article
July 2013

Gastric Helicobacter infection induces iron deficiency in the INS-GAS mouse.

PLoS One 2012 19;7(11):e50194. Epub 2012 Nov 19.

Molecular Gastroenterology, Leeds Institute of Molecular Medicine, St James's University Hospital, Leeds, United Kingdom.

View Article
May 2013

The role of plasminogen activator inhibitor-1 in gastric mucosal protection.

Am J Physiol Gastrointest Liver Physiol 2013 May 14;304(9):G814-22. Epub 2013 Mar 14.

Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.

View Article
May 2013

Correlation between a short-term intravenous octreotide suppression test and response to antrectomy in patients with type-1 gastric neuroendocrine tumours.

Eur J Gastroenterol Hepatol 2013 Apr;25(4):474-81

Department of Gastroenterology, Institute of Translational Medicine, University of Liverpool, Liverpool L69 3GE, UK.

View Article
April 2013

Gastrin receptor pharmacology.

Curr Gastroenterol Rep 2012 Dec;14(6):453-9

Departments of Cell and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

View Article
December 2012

Pro-GRP-derived peptides are expressed in colorectal cancer cells and tumors and are biologically active in vivo.

Endocrinology 2012 Mar 27;153(3):1082-92. Epub 2011 Dec 27.

University of Melbourne Department of Surgery, Austin Health, Heidelberg, 3084 Victoria, Australia.

View Article
March 2012

Gastrin stimulates expression of plasminogen activator inhibitor-1 in gastric epithelial cells.

Am J Physiol Gastrointest Liver Physiol 2011 Sep 30;301(3):G446-53. Epub 2010 Dec 30.

Physiological Laboratory, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.

View Article
September 2011

IFN-γ inhibits gastric carcinogenesis by inducing epithelial cell autophagy and T-cell apoptosis.

Cancer Res 2011 Jun 21;71(12):4247-59. Epub 2011 Apr 21.

Department of Medicine, College of Physicians & Surgeons, Columbia University, New York, USA.

View Article
June 2011

Zollinger-Ellison syndrome: still a diagnostic challenge in the 21st century?

Authors:
D Mark Pritchard

Gastroenterology 2011 May 26;140(5):1380-3. Epub 2011 Mar 26.

View Article
May 2011

The management of gastric polyps.

Gut 2010 Sep 30;59(9):1270-6. Epub 2010 Jul 30.

Digestive Diseases Centre, Royal Derby Hospital, Uttoxeter Road, Derby DE22 3NE, UK.

View Article
September 2010

Conditional deletion of IkappaB-kinase-beta accelerates helicobacter-dependent gastric apoptosis, proliferation, and preneoplasia.

Gastroenterology 2010 Mar 4;138(3):1022-34.e1-10. Epub 2009 Dec 4.

Division of Digestive and Liver Disease, Department of Medicine, Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA.

View Article
March 2010

KLF4 gene expression is inhibited by the notch signaling pathway that controls goblet cell differentiation in mouse gastrointestinal tract.

Am J Physiol Gastrointest Liver Physiol 2009 Mar 24;296(3):G490-8. Epub 2008 Dec 24.

Department of Pathology, Microbiology and Immunology, University of South Carolina, School of Medicine, 6439 Garners Ferry Road, Columbia, SC 29208, USA.

View Article
March 2009

Suppression of apoptosis, crypt hyperplasia, and altered differentiation in the colonic epithelia of bak-null mice.

Gastroenterology 2009 Mar 19;136(3):943-52. Epub 2008 Nov 19.

Division of Gastroenterology, University of Liverpool, Liverpool, United Kingdom.

View Article
March 2009

Increased expression of the urokinase plasminogen activator system by Helicobacter pylori in gastric epithelial cells.

Am J Physiol Gastrointest Liver Physiol 2008 Sep 3;295(3):G431-41. Epub 2008 Jul 3.

Physiological Laboratory, School of Biomedical Sciences, University of Liverpool, Crown St., Liverpool L69 3BX, UK.

View Article
September 2008

Helicobacter and gastrin stimulate Reg1 expression in gastric epithelial cells through distinct promoter elements.

Am J Physiol Gastrointest Liver Physiol 2007 Jul 26;293(1):G347-54. Epub 2007 Apr 26.

Physiological Laboratory, School of Biomedical Sciences, University of Liverpool, Crown Street, Liverpool, UK.

View Article
July 2007

Arthroscopic rotator cuff repair with double-row fixation.

J Bone Joint Surg Am 2007 Jun;89(6):1248-57

Cape Shoulder Institute, P.O. Box 15741, Panorama 7506, South Africa.

View Article
June 2007

Increased gastric expression of MMP-7 in hypergastrinemia and significance for epithelial-mesenchymal signaling.

Am J Physiol Gastrointest Liver Physiol 2007 Apr 11;292(4):G1133-40. Epub 2007 Jan 11.

Physiological Laboratory, School of Biomedical Sciences, University of Liverpool, Crown St., Liverpool L69 3BX, UK.

View Article
April 2007

Helicobacter pylori and gastric cancer.

Curr Opin Gastroenterol 2006 Nov;22(6):620-5

Division of Gastroenterology, University of Liverpool, Liverpool, UK.

View Article
November 2006

Gastrin-induced apoptosis contributes to carcinogenesis in the stomach.

Lab Invest 2006 Oct 7;86(10):1037-51. Epub 2006 Aug 7.

Division of Gastroenterology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA.

View Article
October 2006

Characterization of epithelial cell shedding from human small intestine.

Lab Invest 2006 Oct 14;86(10):1052-63. Epub 2006 Aug 14.

Division of Gastroenterology, School of Clinical Sciences, University of Liverpool, Liverpool, UK.

View Article
October 2006

Gastrin increases murine intestinal crypt regeneration following injury.

Gastroenterology 2006 Apr;130(4):1169-80

Division of Gastroenterology, University of Liverpool, Liverpool, UK.

View Article
April 2006

Progastrin stimulates murine colonic epithelial mitosis after DNA damage.

Gastroenterology 2003 May;124(5):1348-57

Department of Medicine, University of Liverpool, England.

View Article
May 2003

Gastrin induces proliferation in Barrett's metaplasia through activation of the CCK2 receptor.

Gastroenterology 2003 Mar;124(3):615-25

Department of Medicine and Physiological Laboratory, University of Liverpool, Liverpool, England.

View Article
March 2003