Publications by authors named "Mark Nicol"

100Publications

Risk factors for Bordetella pertussis disease in hospitalized children.

PLoS One 2020 15;15(10):e0240717. Epub 2020 Oct 15.

SA-MRC Unit on Child & Adolescent Lung Health, University of Cape Town, Cape Town, South Africa.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0240717PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7561157PMC
October 2020

Laboratory development of a simple stool sample processing method diagnosis of pediatric tuberculosis using Xpert Ultra.

Tuberculosis (Edinb) 2020 Oct 3;125:102002. Epub 2020 Oct 3.

IRD UMI 233 TransVIHMI- UM-INSERM U1175, Montpellier, France. Electronic address:

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http://dx.doi.org/10.1016/j.tube.2020.102002DOI Listing
October 2020

Co-detection of Bordetella pertussis and other respiratory organisms in children hospitalised with lower respiratory tract infection.

Sci Rep 2020 Oct 2;10(1):16412. Epub 2020 Oct 2.

SA-MRC Unit On Child and Adolescent Lung Health, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1038/s41598-020-73462-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532201PMC
October 2020

Early-life respiratory syncytial virus lower respiratory tract infection in a South African birth cohort: epidemiology and effect on lung health.

Lancet Glob Health 2020 10;8(10):e1316-e1325

Division of Medical Microbiology, University of Cape Town, Cape Town, South Africa; Division of Infection and Immunity, Department of Biomedical Sciences, University of Western Australia, Perth, WA, Australia.

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http://dx.doi.org/10.1016/S2214-109X(20)30251-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511798PMC
October 2020

Key advances and remaining challenges in childhood and adolescent tuberculosis.

Paediatr Respir Rev 2020 Aug 1. Epub 2020 Aug 1.

Department of Paediatrics & Child Health and SA-MRC Unit on Child & Adolescent Health, University of Cape Town, South Africa.

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http://dx.doi.org/10.1016/j.prrv.2020.07.008DOI Listing
August 2020

Advances in the diagnosis of pulmonary tuberculosis in children.

Paediatr Respir Rev 2020 May 25. Epub 2020 May 25.

Department of Paediatrics and Child Health, and SA-MRC Unit on Child & Adolescent Health, University of Cape Town and Red Cross War Memorial Children's Hospital, Cape Town, South Africa.

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http://dx.doi.org/10.1016/j.prrv.2020.05.003DOI Listing
May 2020

The Influence of DNA Extraction and Lipid Removal on Human Milk Bacterial Profiles.

Methods Protoc 2020 May 15;3(2). Epub 2020 May 15.

Division of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, Observatory 7925, University of Cape Town, Cape Town 7700, South Africa.

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http://dx.doi.org/10.3390/mps3020039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7359716PMC
May 2020

Optimizing 16S rRNA gene profile analysis from low biomass nasopharyngeal and induced sputum specimens.

BMC Microbiol 2020 May 12;20(1):113. Epub 2020 May 12.

Division of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1186/s12866-020-01795-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7218582PMC
May 2020

Differential RD-1-specific IFN-γ host responses to diverse Mycobacterium tuberculosis strains in HIV-uninfected persons may be explained by genotypic variation in the ESX-1 region.

Int J Infect Dis 2020 Jul 24;96:240-243. Epub 2020 Apr 24.

Centre for Lung Infection and Immunity, Division of Pulmonology, Department of Medicine and UCT Lung Institute & South African MRC/UCT Centre for the Study of Antimicrobial Resistance, University of Cape Town, Cape Town, South Africa; Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa; Faculty of Infectious and Tropical Diseases, Department of Infection Biology, London School of Hygiene and Tropical Medicine, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ijid.2020.04.053DOI Listing
July 2020

First clinical assessment of a prototype assay to detect the enzymatic activity of β-lactamase as a marker for pulmonary tuberculosis.

Diagn Microbiol Infect Dis 2020 Jun 19;97(2):115026. Epub 2020 Feb 19.

FIND, Chemin des Mines 9, 1202, Geneva, Switzerland; Division of Tropical Medicine, Center of Infectious Diseases, University Hospital of Heidelberg, Im Neuenheimer Feld 324, 69120, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.diagmicrobio.2020.115026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262578PMC
June 2020

Correction to: Diagnostic accuracy of the Xpert MTB/Rif Ultra for tuberculosis adenitis.

BMC Infect Dis 2020 03 2;20(1):187. Epub 2020 Mar 2.

Division of Haematology, Department of Medicine, University of Cape Town, Anzio Rd, Observatory, Cape Town, 7925, South Africa.

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http://dx.doi.org/10.1186/s12879-020-4917-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7050142PMC
March 2020

The Determinants of the Human Milk Metabolome and Its Role in Infant Health.

Metabolites 2020 Feb 20;10(2). Epub 2020 Feb 20.

Division of Medical Microbiology, Department of Pathology, University of Cape Town, Observatory, Cape Town 7925, South Africa.

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http://dx.doi.org/10.3390/metabo10020077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7074355PMC
February 2020

"A very humiliating illness": a qualitative study of patient-centered Care for Rifampicin-Resistant Tuberculosis in South Africa.

BMC Public Health 2020 Jan 17;20(1):76. Epub 2020 Jan 17.

Division of Medical Microbiology, Department of Pathology, University of Cape Town, Cape town, South Africa.

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http://dx.doi.org/10.1186/s12889-019-8035-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969445PMC
January 2020

Diagnostic accuracy of the Xpert MTB/Rif Ultra for tuberculosis adenitis.

BMC Infect Dis 2020 Jan 13;20(1):33. Epub 2020 Jan 13.

Division of Haematology, Department of Medicine, University of Cape Town, Anzio Rd, Observatory, Cape Town, 7925, South Africa.

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http://dx.doi.org/10.1186/s12879-019-4749-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958753PMC
January 2020

'SILVAMP TB LAM' rapid urine tuberculosis test predicts mortality in hospitalized HIV patients in South Africa.

Clin Infect Dis 2020 Jan 9. Epub 2020 Jan 9.

Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory, Republic of South Africa.

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http://dx.doi.org/10.1093/cid/ciaa024DOI Listing
January 2020

Association of maternal prenatal psychological stressors and distress with maternal and early infant faecal bacterial profile.

Acta Neuropsychiatr 2020 Feb 20;32(1):32-42. Epub 2019 Dec 20.

Department of Psychiatry and Mental Health and Neuroscience Institute, Brain Behaviour Unit, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1017/neu.2019.43DOI Listing
February 2020

Prevalence and antibiotic susceptibility patterns of enteric bacterial pathogens in human and non-human sources in an urban informal settlement in Cape Town, South Africa.

BMC Microbiol 2019 11 6;19(1):244. Epub 2019 Nov 6.

Division of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, University of Cape Town and National Health Laboratory Services, Cape Town, South Africa.

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http://dx.doi.org/10.1186/s12866-019-1620-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836408PMC
November 2019

Strengthening Diagnosis of Pulmonary Tuberculosis in Children: The Role of Xpert MTB/RIF Ultra.

Pediatrics 2019 11;144(5)

Division of Infection and Immunity, School of Biomedical Sciences, The University of Western Australia, Perth, Australia.

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http://dx.doi.org/10.1542/peds.2019-2944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6855810PMC
November 2019

False rifampicin resistant results using Xpert MTB/RIF on urine samples in hospitalised HIV-infected patients.

South Afr J HIV Med 2019 28;20(1):978. Epub 2019 Aug 28.

Division of HIV, Infectious Diseases and Global Medicine at Zuckerberg San Francisco General Hospital and Trauma Center, Department of Medicine, University of California, San Francisco, United States.

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http://dx.doi.org/10.4102/sajhivmed.v20i1.978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6739559PMC
August 2019

Microbiological diagnosis of pulmonary tuberculosis in children by oral swab polymerase chain reaction.

Sci Rep 2019 07 25;9(1):10789. Epub 2019 Jul 25.

Department of Environmental and Occupational Health Sciences, School of Public Health, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1038/s41598-019-47302-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658562PMC
July 2019

Etiology of Pulmonary Infections in Human Immunodeficiency Virus-infected Inpatients Using Sputum Multiplex Real-time Polymerase Chain Reaction.

Clin Infect Dis 2020 Mar;70(6):1147-1152

Division of Infectious Diseases and Human Immunodeficiency Virus Medicine, Department of Medicine, University of Cape Town, South Africa.

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http://dx.doi.org/10.1093/cid/ciz332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108142PMC
March 2020

Clinical, microbiologic, and immunologic determinants of mortality in hospitalized patients with HIV-associated tuberculosis: A prospective cohort study.

PLoS Med 2019 07 5;16(7):e1002840. Epub 2019 Jul 5.

Wellcome Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1371/journal.pmed.1002840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611568PMC
July 2019

Influence of Socio-Economic and Psychosocial Profiles on the Human Breast Milk Bacteriome of South African Women.

Nutrients 2019 Jun 20;11(6). Epub 2019 Jun 20.

Division of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, Observatory 7925, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.3390/nu11061390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627120PMC
June 2019

Nasopharyngeal Carriage of Antimicrobial-Resistant Pneumococci in an Intensively Sampled South African Birth Cohort.

Front Microbiol 2019 27;10:610. Epub 2019 Mar 27.

Division of Medical Microbiology, Faculty of Health Science, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.3389/fmicb.2019.00610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446970PMC
March 2019

Longitudinal Population Dynamics of in the Nasopharynx During the First Year of Life.

Front Genet 2019 15;10:198. Epub 2019 Mar 15.

Division of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.3389/fgene.2019.00198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428701PMC
March 2019

Lower Respiratory Tract Infections in Children in a Well-vaccinated South African Birth Cohort: Spectrum of Disease and Risk Factors.

Clin Infect Dis 2019 10;69(9):1588-1596

Department of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital and Medical Research Council Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa.

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https://academic.oup.com/cid/advance-article/doi/10.1093/cid
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http://dx.doi.org/10.1093/cid/ciz017DOI Listing
October 2019

Brief Report: Real-World Performance and Interobserver Agreement of Urine Lipoarabinomannan in Diagnosing HIV-Associated Tuberculosis in an Emergency Center.

J Acquir Immune Defic Syndr 2019 05;81(1):e10-e14

Department of Medicine, Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1097/QAI.0000000000002002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522362PMC
May 2019

Indoor air pollution and tobacco smoke exposure: impact on nasopharyngeal bacterial carriage in mothers and infants in an African birth cohort study.

ERJ Open Res 2019 Feb 4;5(1). Epub 2019 Feb 4.

Dept of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, and SAMRC Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa.

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http://openres.ersjournals.com/lookup/doi/10.1183/23120541.0
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http://dx.doi.org/10.1183/23120541.00052-2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360211PMC
February 2019

Human Breast Milk Bacteriome in Health and Disease.

Nutrients 2018 Nov 3;10(11). Epub 2018 Nov 3.

Division of Medical Microbiology, Department of Pathology, University of Cape Town, Observatory, Cape Town 7925, South Africa.

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http://www.mdpi.com/2072-6643/10/11/1643
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http://dx.doi.org/10.3390/nu10111643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266581PMC
November 2018

Age-related waning of immune responses to BCG in healthy children supports the need for a booster dose of BCG in TB endemic countries.

Sci Rep 2018 10 17;8(1):15309. Epub 2018 Oct 17.

Academic Department of Paediatrics, St Marys Campus, Imperial College London, 2nd Floor Wright-Fleming Building, Norfolk Place, London, W2 1PG, UK.

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http://www.nature.com/articles/s41598-018-33499-4
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http://dx.doi.org/10.1038/s41598-018-33499-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193026PMC
October 2018

Treatment of bronchiectasis exacerbations in children: which antibiotic?

Lancet 2018 10 18;392(10154):1169-1170. Epub 2018 Sep 18.

Division of Medical Microbiology, Department of Pathology, University of Cape Town, Cape Town, South Africa; National Health Laboratory Service of South Africa, Cape Town, South Africa.

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http://dx.doi.org/10.1016/S0140-6736(18)32004-XDOI Listing
October 2018

Characterisation of STEC and other diarrheic E. coli isolated on CHROMagar™STEC at a tertiary referral hospital, Cape Town.

BMC Microbiol 2018 06 8;18(1):55. Epub 2018 Jun 8.

Division of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, University of Cape Town and National Health Laboratory Services, Cape Town, South Africa.

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http://dx.doi.org/10.1186/s12866-018-1195-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994027PMC
June 2018

Gene expression in cord blood links genetic risk for neurodevelopmental disorders with maternal psychological distress and adverse childhood outcomes.

Brain Behav Immun 2018 10 20;73:320-330. Epub 2018 May 20.

Department of Psychiatry and Mental Health, University of Cape Town, South Africa; South African Medical Research Council (SAMRC) Unit on Risk & Resilience in Mental Disorders, University of Cape Town, Cape Town, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2018.05.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191930PMC
October 2018

Precision medicine for drug-resistant tuberculosis in high-burden countries: is individualised treatment desirable and feasible?

Lancet Infect Dis 2018 09 13;18(9):e282-e287. Epub 2018 Mar 13.

Division of Medical Microbiology and the Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa; National Health Laboratory Service, Johannesburg, South Africa.

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http://dx.doi.org/10.1016/S1473-3099(18)30104-XDOI Listing
September 2018

Accuracy of Xpert Mtb/Rif Ultra for the Diagnosis of Pulmonary Tuberculosis in Children.

Pediatr Infect Dis J 2018 10;37(10):e261-e263

Department of Paediatrics and Child Health, MRC Unit on Child and Adolescent Health, University of Cape Town and Red Cross War Memorial Children's Hospital, Cape Town, South Africa.

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http://dx.doi.org/10.1097/INF.0000000000001960DOI Listing
October 2018

Tuberculin skin test conversion and primary progressive tuberculosis disease in the first 5 years of life: a birth cohort study from Cape Town, South Africa.

Lancet Child Adolesc Health 2018 01;2(1):46-55

Department of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital and Medical Research Council Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S23524642173014
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http://dx.doi.org/10.1016/S2352-4642(17)30149-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810304PMC
January 2018

Tuberculosis eradication: renewed commitment and global investment required.

Lancet Infect Dis 2018 03 7;18(3):228-229. Epub 2017 Dec 7.

Division of Medical Microbiology, University of Cape Town, Cape Town, 7925, South Africa; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa; National Health Laboratory Service, Johannesburg, South Africa.

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http://dx.doi.org/10.1016/S1473-3099(17)30692-8DOI Listing
March 2018

Preventing tuberculosis-related death in children with HIV.

Lancet HIV 2018 02 23;5(2):e62-e64. Epub 2017 Nov 23.

Division of Medical Microbiology, Department of Pathology, University of Cape Town, 7925 Cape Town, South Africa; National Health Laboratory Service, Cape Town, South Africa; Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa. Electronic address:

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http://dx.doi.org/10.1016/S2352-3018(17)30208-4DOI Listing
February 2018

Genome Sequence for Shiga Toxin-Producing O26:H11, Associated with a Cluster of Hemolytic-Uremic Syndrome Cases in South Africa, 2017.

Genome Announc 2017 Sep 21;5(38). Epub 2017 Sep 21.

Centre for Enteric Diseases, National Institute for Communicable Diseases, National Health Laboratory Service, Johannesburg, South Africa.

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http://dx.doi.org/10.1128/genomeA.00989-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609422PMC
September 2017

Xpert MTB/RIF Ultra: a gamechanger for tuberculous meningitis?

Lancet Infect Dis 2018 01 14;18(1):6-8. Epub 2017 Sep 14.

Division of Medical Microbiology, Department of Pathology, Cape Town 7925, South Africa; Institute of Infectious Diseases and Molecular Medicine, Cape Town 7925, South Africa; University of Cape Town, Cape Town 7925, South Africa; National Health Laboratory Service, Cape Town, South Africa. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(17)30536-4DOI Listing
January 2018

Proteomic comparison of three clinical diarrhoeagenic drug-resistant Escherichia coli isolates grown on CHROMagar™STEC media.

J Proteomics 2018 05 5;180:25-35. Epub 2017 Sep 5.

Division of Chemical & Systems Biology, Department of Integrative Biomedical Sciences, University of Cape Town, Cape Town, South Africa; Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2017.09.003DOI Listing
May 2018

Disseminated tuberculosis among hospitalised HIV patients in South Africa: a common condition that can be rapidly diagnosed using urine-based assays.

Sci Rep 2017 09 7;7(1):10931. Epub 2017 Sep 7.

Wellcome Trust Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1038/s41598-017-09895-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589905PMC
September 2017

Advances in the diagnosis of pneumonia in children.

BMJ 2017 Jul 26;358:j2739. Epub 2017 Jul 26.

Division of Medical Microbiology, Department of Pathology, University of Cape Town.

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http://dx.doi.org/10.1136/bmj.j2739DOI Listing
July 2017

Impact of Point-of-Care Xpert MTB/RIF on Tuberculosis Treatment Initiation. A Cluster-randomized Trial.

Am J Respir Crit Care Med 2017 10;196(7):901-910

1 Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom.

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http://dx.doi.org/10.1164/rccm.201702-0278OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5649979PMC
October 2017

Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study.

Authors:
Ting Shi David A McAllister Katherine L O'Brien Eric A F Simoes Shabir A Madhi Bradford D Gessner Fernando P Polack Evelyn Balsells Sozinho Acacio Claudia Aguayo Issifou Alassani Asad Ali Martin Antonio Shally Awasthi Juliet O Awori Eduardo Azziz-Baumgartner Henry C Baggett Vicky L Baillie Angel Balmaseda Alfredo Barahona Sudha Basnet Quique Bassat Wilma Basualdo Godfrey Bigogo Louis Bont Robert F Breiman W Abdullah Brooks Shobha Broor Nigel Bruce Dana Bruden Philippe Buchy Stuart Campbell Phyllis Carosone-Link Mandeep Chadha James Chipeta Monidarin Chou Wilfrido Clara Cheryl Cohen Elizabeth de Cuellar Duc-Anh Dang Budragchaagiin Dash-Yandag Maria Deloria-Knoll Mukesh Dherani Tekchheng Eap Bernard E Ebruke Marcela Echavarria Carla Cecília de Freitas Lázaro Emediato Rodrigo A Fasce Daniel R Feikin Luzhao Feng Angela Gentile Aubree Gordon Doli Goswami Sophie Goyet Michelle Groome Natasha Halasa Siddhivinayak Hirve Nusrat Homaira Stephen R C Howie Jorge Jara Imane Jroundi Cissy B Kartasasmita Najwa Khuri-Bulos Karen L Kotloff Anand Krishnan Romina Libster Olga Lopez Marilla G Lucero Florencia Lucion Socorro P Lupisan Debora N Marcone John P McCracken Mario Mejia Jennifer C Moisi Joel M Montgomery David P Moore Cinta Moraleda Jocelyn Moyes Patrick Munywoki Kuswandewi Mutyara Mark P Nicol D James Nokes Pagbajabyn Nymadawa Maria Tereza da Costa Oliveira Histoshi Oshitani Nitin Pandey Gláucia Paranhos-Baccalà Lia N Phillips Valentina Sanchez Picot Mustafizur Rahman Mala Rakoto-Andrianarivelo Zeba A Rasmussen Barbara A Rath Annick Robinson Candice Romero Graciela Russomando Vahid Salimi Pongpun Sawatwong Nienke Scheltema Brunhilde Schweiger J Anthony G Scott Phil Seidenberg Kunling Shen Rosalyn Singleton Viviana Sotomayor Tor A Strand Agustinus Sutanto Mariam Sylla Milagritos D Tapia Somsak Thamthitiwat Elizabeth D Thomas Rafal Tokarz Claudia Turner Marietjie Venter Sunthareeya Waicharoen Jianwei Wang Wanitda Watthanaworawit Lay-Myint Yoshida Hongjie Yu Heather J Zar Harry Campbell Harish Nair

Lancet 2017 Sep 7;390(10098):946-958. Epub 2017 Jul 7.

Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK; Public Health Foundation of India, New Delhi, India. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(17)30938-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592248PMC
September 2017

Remembering the basics: interventions to improve sputum collection for tuberculosis diagnosis.

Lancet Glob Health 2017 08 15;5(8):e728-e729. Epub 2017 Jun 15.

Division of Medical Microbiology, Department of Pathology, University of Cape Town, Cape Town 7700, South Africa; Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town 7700, South Africa; National Health Laboratory Service, Johannesburg, South Africa. Electronic address:

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http://dx.doi.org/10.1016/S2214-109X(17)30227-9DOI Listing
August 2017

Regulatory T Cells and Pro-inflammatory Responses Predominate in Children with Tuberculosis.

Front Immunol 2017 25;8:448. Epub 2017 Apr 25.

Academic Department of Paediatrics, Imperial College London, London, UK.

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http://dx.doi.org/10.3389/fimmu.2017.00448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403917PMC
April 2017

The Influence of HIV on the Evolution of Mycobacterium tuberculosis.

Mol Biol Evol 2017 07;34(7):1654-1668

Wellcome Centre for Infectious Disease Research in Africa, Institute of Infectious Disease and Molecular Medicine, and Department of Medicine, University of Cape Town, Cape Town, South Africa.

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https://academic.oup.com/mbe/article-lookup/doi/10.1093/molb
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http://dx.doi.org/10.1093/molbev/msx107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455964PMC
July 2017

Highly sensitive sequence specific qPCR detection of Mycobacterium tuberculosis complex in respiratory specimens.

Tuberculosis (Edinb) 2016 12 10;101:114-124. Epub 2016 Sep 10.

Center for Innovation in Global Health Technologies (CIGHT), Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tube.2016.09.002DOI Listing
December 2016

How should tuberculosis molecular diagnostics be adapted for use in seriously ill HIV patients?

Authors:
Mark P Nicol

Expert Rev Mol Diagn 2016 12;16(12):1237-1239

a Division of Medical Microbiology, Department of Pathology and Institute for Infectious Diseases and Molecular Medicine , University of Cape Town and National Health Laboratory Service , Cape Town , South Africa.

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http://dx.doi.org/10.1080/14737159.2016.1257386DOI Listing
December 2016

Respiratory microbes present in the nasopharynx of children hospitalised with suspected pulmonary tuberculosis in Cape Town, South Africa.

BMC Infect Dis 2016 10 24;16(1):597. Epub 2016 Oct 24.

Division of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1186/s12879-016-1934-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075757PMC
October 2016

Tuberculosis Diagnostics: State of the Art and Future Directions.

Microbiol Spectr 2016 10;4(5)

FIND, 1202 Geneva, Switzerland.

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http://dx.doi.org/10.1128/microbiolspec.TBTB2-0019-2016DOI Listing
October 2016

Human brucellosis in South Africa: Public health and diagnostic pitfalls.

S Afr Med J 2016 Aug 1;106(9):883-5. Epub 2016 Aug 1.

National Health Laboratory Service, Microbiology Laboratory, Groote Schuur Hospital, Cape Town, South Africa; Division of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, South Africa.

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http://dx.doi.org/10.7196/SAMJ.2016.v106i9.11020DOI Listing
August 2016

Current Knowledge and Future Research Directions on Fecal Bacterial Patterns and Their Association with Asthma.

Front Microbiol 2016 29;7:838. Epub 2016 Jun 29.

Division of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, University of Cape TownCape Town, South Africa; Institute of Infectious Diseases and Molecular Medicine, University of Cape TownCape Town, South Africa.

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http://dx.doi.org/10.3389/fmicb.2016.00838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925717PMC
July 2016

Childhood pneumonia - the Drakenstein Child Health Study.

S Afr Med J 2016 Jun 15;106(7):642-3. Epub 2016 Jun 15.

Department of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital and Medical Research Council Unit on Child and Adolescent Health, Faculty of Health Sciences, University of Cape Town, South Africa.

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http://dx.doi.org/10.7196/SAMJ.2016.v106i7.11108DOI Listing
June 2016

Fecal Carriage of Staphylococcus aureus in the Hospital and Community Setting: A Systematic Review.

Front Microbiol 2016 10;7:449. Epub 2016 May 10.

Division of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, University of Cape TownCape Town, South Africa; Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape TownCape Town, South Africa.

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http://dx.doi.org/10.3389/fmicb.2016.00449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861718PMC
May 2016

Aetiology of childhood pneumonia in a well vaccinated South African birth cohort: a nested case-control study of the Drakenstein Child Health Study.

Lancet Respir Med 2016 06 21;4(6):463-72. Epub 2016 Apr 21.

Division of Medical Microbiology, University of Cape Town, Cape Town, South Africa; National Health Laboratory Services, Cape Town, South Africa.

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http://dx.doi.org/10.1016/S2213-2600(16)00096-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989125PMC
June 2016

Incidence and Diagnosis of Pertussis in South African Children Hospitalized With Lower Respiratory Tract Infection.

Pediatr Infect Dis J 2016 06;35(6):611-6

From the *Department of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, South Africa; †MRC Unit on Child and Adolescent Health, University of Cape Town, Cape Town, South Africa; and ‡Division of Medical Microbiology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; §National Health Laboratory Service, Groote Schuur Hospital, Cape Town, South Africa; ¶Institute of Infectious Disease and Molecular Medicine and ||Vaccines for Africa Initiative, Division of Medical Microbiology, University of Cape Town, Cape Town, South Africa.

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http://dx.doi.org/10.1097/INF.0000000000001132DOI Listing
June 2016

Molecular characterisation and epidemiological investigation of an outbreak of blaOXA-181 carbapenemase-producing isolates of Klebsiella pneumoniae in South Africa.

S Afr Med J 2015 Nov 8;105(12):1030-5. Epub 2015 Nov 8.

Centre for Opportunistic, Tropical and Hospital Infections, National Institute for Communicable Diseases, Groote Schuur Hospital, Cape Town, South Africa; National Health Laboratory Service, Groote Schuur Hospital, Cape Town, South Africa; Division of Medical Microbiology, University of Cape Town, South Africa.

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http://dx.doi.org/10.7196/SAMJ.2015.v105i12.9926DOI Listing
November 2015

Incidence of childhood pneumonia: facility-based surveillance estimate compared to measured incidence in a South African birth cohort study.

BMJ Open 2015 Dec 18;5(12):e009111. Epub 2015 Dec 18.

Department of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital and MRC Unit on Child and Adolescent Health, University of Cape Town, Cape Town, Western Cape, South Africa.

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http://dx.doi.org/10.1136/bmjopen-2015-009111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691755PMC
December 2015

HIV-Related Medical Admissions to a South African District Hospital Remain Frequent Despite Effective Antiretroviral Therapy Scale-Up.

Medicine (Baltimore) 2015 Dec;94(50):e2269

From the Clinical Infectious Diseases Research Initiative, Institute of Infectious Disease and Molecular Medicine (GM, CS, LB); Department of Medicine, Faculty of Health Sciences, University of Cape Town (GM, RB, CS, SDL); Department of Medicine, Khayelitsha District Hospital, South Africa (GM, RB); Department of Medicine, Imperial College London, London, UK (GM); The Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, South Africa (ADK, SDL); Department of Medicine, University of California San Francisco School of Medicine, San Francisco, CA, USA (ADK); Department of Global Health, Academic Medical Center, Amsterdam Institute for Global Health and Development, University of Amsterdam, Amsterdam, The Netherlands (ADK); School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town (AB); Health Impact Assessment Directorate, Western Cape Department of Health (AB); Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town (AB); Department of Medicine, Mitchells Plain Hospital (GVW); Division of Medical Microbiology, Faculty of Health Sciences, University of Cape Town (MPN); National Health Laboratory Service, South Africa (MPN); and Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK (SDL).

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http://dx.doi.org/10.1097/MD.0000000000002269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5058922PMC
December 2015

Diagnosis of Pulmonary Tuberculosis in Children: Assessment of the 2012 National Institutes of Health Expert Consensus Criteria.

Clin Infect Dis 2015 Oct;61Suppl 3:S173-8

Division of Medical Microbiology and Institute for Infectious Diseases and Molecular Medicine, University of Cape Town, National Health Laboratory Service, Groote Schuur Hospital, South Africa.

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http://dx.doi.org/10.1093/cid/civ622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583577PMC
October 2015

A Blueprint to Address Research Gaps in the Development of Biomarkers for Pediatric Tuberculosis.

Clin Infect Dis 2015 Oct;61Suppl 3:S164-72

Department of Science and Technology and National Research Foundation Centre of Excellence for Biomedical Tuberculosis Research/Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, South Africa.

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http://dx.doi.org/10.1093/cid/civ613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583573PMC
October 2015

Clinical Predictors of Culture-confirmed Pulmonary Tuberculosis in Children in a High Tuberculosis and HIV Prevalence Area.

Pediatr Infect Dis J 2015 Sep;34(9):e206-10

From the *Department of Pediatrics and Child Health, University of Cape Town and Tygerberg Childrens Hospital, Cape Town, South Africa; †Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa; ‡Division of Clinical Pharmacology, Department of Medicine and Child Health, University of Cape Town, Cape Town, South Africa; §Red Cross War Memorial Children's Hospital, Cape Town, South Africa; ¶Department of Radiology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; ‖Division of Medical Microbiology, Department of Clinical Laboratory Sciences, Institute for Infectious Diseases and Molecular Medicine, University of Cape Town and National Health Laboratory Service of South Africa, Cape Town, South Africa; and **Department of Paediatrics and Child Health, Red Cross Childrens Hospital, University of Cape Town, South Africa and MRC unit on Child and Adolescent Lung Health, Cape Town, South Africa.

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http://dx.doi.org/10.1097/INF.0000000000000792DOI Listing
September 2015