Mark N Kirstein

Mark N Kirstein

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Mark N Kirstein

Mark N Kirstein

Publications by authors named "Mark N Kirstein"

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31Publications

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A phase I dose finding study of intravenous voriconazole in pediatric patients undergoing hematopoietic cell transplantation.

Bone Marrow Transplant 2019 Nov 25. Epub 2019 Nov 25.

Department of Pediatrics, Division of Blood and Marrow Transplant, University of Minnesota School of Medicine, Minneapolis, MN, USA.

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http://dx.doi.org/10.1038/s41409-019-0757-0DOI Listing
November 2019

Gemcitabine and metabolite pharmacokinetics in advanced NSCLC patients after bronchial artery infusion and intravenous infusion.

Cancer Chemother Pharmacol 2019 02 12;83(2):387-391. Epub 2018 Dec 12.

Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, 55455, USA.

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http://link.springer.com/10.1007/s00280-018-3757-7
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http://dx.doi.org/10.1007/s00280-018-3757-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859936PMC
February 2019

Pharmacokinetic-pharmacodynamic modelling of acute N-terminal pro B-type natriuretic peptide after doxorubicin infusion in breast cancer.

Br J Clin Pharmacol 2016 09 3;82(3):773-83. Epub 2016 Jun 3.

Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, 55455, USA.

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http://dx.doi.org/10.1111/bcp.12989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338127PMC
September 2016

Pathway-based pharmacogenomics of gemcitabine pharmacokinetics in patients with solid tumors.

Pharmacogenomics 2012 Jul;13(9):1009-21

Department of Experimental & Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.2217/pgs.12.81DOI Listing
July 2012

Cytotoxic purine nucleoside analogues bind to A1, A2A, and A3 adenosine receptors.

Naunyn Schmiedebergs Arch Pharmacol 2012 May 17;385(5):519-25. Epub 2012 Jan 17.

College of Pharmacy, Department of Experimental and Clinical Pharmacology, University of Minnesota, 308 Harvard ST SE, Minneapolis, MN, USA.

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http://dx.doi.org/10.1007/s00210-011-0719-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831620PMC
May 2012

Pharmacodynamic modeling of sequence-dependent antitumor activity of insulin-like growth factor blockade and gemcitabine.

AAPS J 2012 Mar 19;14(1):1-9. Epub 2011 Nov 19.

Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, 55455, USA.

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http://dx.doi.org/10.1208/s12248-011-9308-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291184PMC
March 2012

Phase 1 trial of gemcitabine with bortezomib in elderly patients with advanced solid tumors.

Am J Clin Oncol 2011 Dec;34(6):597-602

Department of Medicine, Division of Hematology, Oncology and Transplantation, Comprehensive Cancer Center, University of Minnesota, Minneapolis, USA.

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http://dx.doi.org/10.1097/COC.0b013e3181f9441fDOI Listing
December 2011

Effect of radiation on the penetration of irinotecan in rat cerebrospinal fluid.

Cancer Chemother Pharmacol 2011 Sep 16;68(3):721-31. Epub 2010 Dec 16.

Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1007/s00280-010-1542-3DOI Listing
September 2011

Combinatorial pharmacologic effects of gemcitabine and its metabolite dFdU.

ChemMedChem 2011 Mar 30;6(3):457-64. Epub 2011 Jan 30.

Department of Medicine, Medical School, University of Minnesota, Minneapolis, Minnesota 55414, USA.

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http://dx.doi.org/10.1002/cmdc.201000447DOI Listing
March 2011

Severe electrolyte disturbances after hyperthermic intraperitoneal chemotherapy: oxaliplatin versus mitomycin C.

Ann Surg Oncol 2011 Jan 8;18(1):174-80. Epub 2010 Jul 8.

Division of Surgical Oncology, Department of Surgery, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1245/s10434-010-1210-1DOI Listing
January 2011

Cytotoxic effect of zoledronic acid-loaded bone cement on giant cell tumor, multiple myeloma, and renal cell carcinoma cell lines.

J Bone Joint Surg Am 2010 Jan;92(1):162-8

Department of Orthopaedic Surgery, University of Minnesota Medical School and Masonic Cancer Center, 2450 Riverside Avenue, R200, Minneapolis, MN 55454, USA.

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http://dx.doi.org/10.2106/JBJS.H.01679DOI Listing
January 2010

Cap-dependent translation blockade and fixed dose-rate gemcitabine: interaction in an in vitro bioreactor system.

Cancer Lett 2009 Oct 12;284(1):37-46. Epub 2009 May 12.

Department of Experimental and Clinical Pharmacology, College of Pharmacy and Comprehensive Cancer Center, University of Minnesota, 717 Delaware St. SE, Minneapolis, MN 55414, USA.

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http://dx.doi.org/10.1016/j.canlet.2009.04.006DOI Listing
October 2009

Pharmacodynamic characterization of gemcitabine cytotoxicity in an in vitro cell culture bioreactor system.

Cancer Chemother Pharmacol 2008 Feb 12;61(2):291-9. Epub 2007 Apr 12.

Department of Experimental and Clinical Pharmacology, College of Pharmacy and Comprehensive Cancer Center, University of Minnesota, 308 Harvard St SE, Minneapolis, MN 55455, USA.

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http://link.springer.com/content/pdf/10.1007/s00280-007-0474
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http://link.springer.com/10.1007/s00280-007-0474-z
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http://dx.doi.org/10.1007/s00280-007-0474-zDOI Listing
February 2008

Exposure-response relationships for oxaliplatin-treated colon cancer cells.

Anticancer Drugs 2008 Jan;19(1):37-44

Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis 55455, USA.

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http://dx.doi.org/10.1097/CAD.0b013e3282f07791DOI Listing
January 2008

Short versus continuous gemcitabine treatment of non-small cell lung cancer in an in vitro cell culture bioreactor system.

Lung Cancer 2007 Nov 25;58(2):196-204. Epub 2007 Jul 25.

Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1016/j.lungcan.2007.06.005DOI Listing
November 2007

Review of selected patents for cancer therapy targeting tumor angiogenesis.

Recent Pat Anticancer Drug Discov 2006 Jun;1(2):153-61

Department of Experimental and Clinical Pharmacology, College of Pharmacy and Comprehensive Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA.

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http://dx.doi.org/10.2174/157489206777442269DOI Listing
June 2006

High-performance liquid chromatographic method for the determination of gemcitabine and 2',2'-difluorodeoxyuridine in plasma and tissue culture media.

J Chromatogr B Analyt Technol Biomed Life Sci 2006 May 11;835(1-2):136-42. Epub 2006 Apr 11.

Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, 308 Harvard St SE, Minneapolis, 55455, USA.

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http://dx.doi.org/10.1016/j.jchromb.2006.03.023DOI Listing
May 2006

Characterization of an in vitro cell culture bioreactor system to evaluate anti-neoplastic drug regimens.

Breast Cancer Res Treat 2006 Apr;96(3):217-25

Department of Experimental and Clinical Pharmacology, College of Pharmacy and Comprehensive Cancer Center, University of Minnesota, Minneapolis 55455, USA.

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http://link.springer.com/content/pdf/10.1007/s10549-005-9004
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http://link.springer.com/10.1007/s10549-005-9004-z
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http://dx.doi.org/10.1007/s10549-005-9004-zDOI Listing
April 2006

A phase I trial defining the maximum tolerated systemic exposure of topotecan in combination with Carboplatin and Etoposide in extensive stage small cell lung cancer.

Cancer Invest 2005 ;23(6):511-9

The Multidisciplinary Thoracic Oncology Program, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1080/07357900500201400DOI Listing
November 2005

Development of a pharmacokinetic limited sampling model for temozolomide and its active metabolite MTIC.

Cancer Chemother Pharmacol 2005 May 26;55(5):433-8. Epub 2005 Jan 26.

Department of Pharmaceutical Sciences, St Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1007/s00280-004-0896-9DOI Listing
May 2005

Population pharmacokinetics of temozolomide and metabolites in infants and children with primary central nervous system tumors.

Cancer Chemother Pharmacol 2003 Dec 16;52(6):435-41. Epub 2003 Sep 16.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1007/s00280-003-0670-4DOI Listing
December 2003

A mechanistic mathematical model of temozolomide myelosuppression in children with high-grade gliomas.

Math Biosci 2003 Nov;186(1):29-41

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, 332 North Lauderdale St., Memphis, TN 38105-2794, USA.

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http://dx.doi.org/10.1016/j.mbs.2003.07.002DOI Listing
November 2003

Molecular targets in the inhibition of angiogenesis.

Expert Opin Ther Targets 2003 Aug;7(4):527-41

Division of Hematology, Oncology and Transplantation, Department of Medicine and Comprehensive Cancer Center, 420 Delaware Street, MMC 480, University of Minnesota, Minneapolis, MN 55455, USA.

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http://www.tandfonline.com/doi/full/10.1517/14728222.7.4.527
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http://dx.doi.org/10.1517/14728222.7.4.527DOI Listing
August 2003

Topoisomerase I interactive agents.

Cancer Chemother Biol Response Modif 2002 ;20:99-123

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, TN 38105, USA.

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May 2003

Determination of plasma topotecan and its metabolite N-desmethyl topotecan as both lactone and total form by reversed-phase liquid chromatography with fluorescence detection.

J Chromatogr B Analyt Technol Biomed Life Sci 2003 Feb;784(2):225-32

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, 332 N. Lauderdale, 38105, Memphis, TN, USA.

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http://dx.doi.org/10.1016/s1570-0232(02)00798-5DOI Listing
February 2003

A pilot study of protracted topotecan dosing using a pharmacokinetically guided dosing approach in children with solid tumors.

Clin Cancer Res 2003 Feb;9(2):633-40

Department of Hematology, St. Jude Children's Research Hospital, University of Tennessee, Memphis, Tennessee 38103, USA.

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February 2003

New liquid chromatographic assay with electrochemical detection for the measurement of amifostine and WR1065.

J Chromatogr B Analyt Technol Biomed Life Sci 2002 Jun;772(2):257-65

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1016/s1570-0232(02)00104-6DOI Listing
June 2002