Mark Molloy

Mark Molloy

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Mark Molloy

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Proteomic screen with the proto-oncogene beta-catenin identifies interaction with Golgi coatomer complex I.

Biochem Biophys Rep 2019 Sep 10;19:100662. Epub 2019 Jul 10.

Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.1016/j.bbrep.2019.100662DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6626114PMC
September 2019

Bioanalytical evaluation of dried plasma spots for monitoring of abiraterone and ∆(4)-abiraterone from cancer patients.

J Chromatogr B Analyt Technol Biomed Life Sci 2019 Sep 31;1126-1127:121741. Epub 2019 Jul 31.

Department of Molecular Sciences, Macquarie University, Sydney, Australia; Bowel Cancer and Biomarker Laboratory, Kolling Institute, The University of Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jchromb.2019.121741DOI Listing
September 2019

Practical Integration of Multi-Run iTRAQ Data.

Methods Mol Biol 2019 ;1977:199-215

Australian Proteome Analysis Facility, Macquarie University, Sydney, NSW, Australia.

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http://dx.doi.org/10.1007/978-1-4939-9232-4_13DOI Listing
August 2019

Targeted Mass Spectrometry of S100 Proteins.

Methods Mol Biol 2019 ;1929:663-678

Bowel Cancer and Biomarker Research, Kolling Institute, Royal North Shore Hospital, The University of Sydney, St. Leonards, Australia.

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http://link.springer.com/10.1007/978-1-4939-9030-6_41
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http://dx.doi.org/10.1007/978-1-4939-9030-6_41DOI Listing
July 2019

Using proteomics to identify ubiquitin ligase-substrate pairs: how novel methods may unveil therapeutic targets for neurodegenerative diseases.

Cell Mol Life Sci 2019 Jul 27;76(13):2499-2510. Epub 2019 Mar 27.

Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, 2 Technology Place, Macquarie Park, Sydney, NSW, 2109, Australia.

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http://dx.doi.org/10.1007/s00018-019-03082-9DOI Listing
July 2019

Inter- and intra-patient variability in pharmacokinetics of abiraterone acetate in metastatic prostate cancer.

Cancer Chemother Pharmacol 2019 Jul 13;84(1):139-146. Epub 2019 May 13.

Department of Medical Oncology, Crown Princess Mary Cancer Centre, Westmead Hospital, Sydney, Australia.

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http://dx.doi.org/10.1007/s00280-019-03862-xDOI Listing
July 2019

Examining Cellular Responses to Kinase Drug Inhibition Through Phosphoproteome Mapping of Substrates.

Methods Mol Biol 2019 ;1888:141-152

Department of Molecular Sciences, ARC Training Centre for Molecular Technology in the Food Industry, Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.1007/978-1-4939-8891-4_8DOI Listing
June 2019

Proteome profiling of Pseudomonas aeruginosa PAO1 identifies novel responders to copper stress.

BMC Microbiol 2019 04 1;19(1):69. Epub 2019 Apr 1.

Department of Molecular Sciences, Macquarie University, Sydney, 2109, Australia.

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http://dx.doi.org/10.1186/s12866-019-1441-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444534PMC
April 2019

iSwathX: an interactive web-based application for extension of DIA peptide reference libraries.

Bioinformatics 2019 Feb;35(3):538-539

Department of Molecular Sciences, Macquarie University, Sydney, NSW, Australia.

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http://dx.doi.org/10.1093/bioinformatics/bty660DOI Listing
February 2019

Precision medicine beyond medical oncology: using molecular analysis to guide treatments of colorectal neoplasia.

Expert Rev Gastroenterol Hepatol 2018 Dec 17;12(12):1179-1181. Epub 2018 Oct 17.

b Head of Colorectal Surgery , Royal North Shore Hospital , Sydney , Australia.

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http://dx.doi.org/10.1080/17474124.2018.1535897DOI Listing
December 2018

Proteomic profile of sex-sorted bull sperm evaluated by SWATH-MS analysis.

Anim Reprod Sci 2018 Nov 22;198:121-128. Epub 2018 Sep 22.

São Paulo State University (UNESP), School of Veterinary Medicine and Animal Science, Department of Animal Reproduction and Veterinary Radiology, Botucatu, Brazil. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03784320183061
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http://dx.doi.org/10.1016/j.anireprosci.2018.09.010DOI Listing
November 2018

Pharmacological Inhibition of Casein Kinase 2 Enhances the Effectiveness of PI3K Inhibition in Colon Cancer Cells.

Anticancer Res 2018 Nov;38(11):6195-6200

Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, Australia

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http://ar.iiarjournals.org/lookup/doi/10.21873/anticanres.12
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http://dx.doi.org/10.21873/anticanres.12973DOI Listing
November 2018

Proteomic phenotyping of metastatic melanoma reveals putative signatures of MEK inhibitor response and prognosis.

Br J Cancer 2018 09 17;119(6):713-723. Epub 2018 Aug 17.

Australian Proteome Analysis Facility (APAF), Department of Chemistry & Biomolecular Sciences, Macquarie University, Sydney, NSW, Australia.

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http://dx.doi.org/10.1038/s41416-018-0227-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173697PMC
September 2018

Multi-laboratory analysis of the variability of shipped samples for proteomics following non-cooled international transport.

Anal Biochem 2018 05 25;548:60-65. Epub 2018 Feb 25.

Mass Spectrometric Proteomics Group, Department of Clinical Chemistry and Central Laboratories, University Medical Center Hamburg-Eppendorf (UKE), Martinistrasse 52, Building N27, Room 00.008, Hamburg, 20246, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ab.2018.02.026DOI Listing
May 2018

Quantitation of the anticancer drug abiraterone and its metabolite Δ(4)-abiraterone in human plasma using high-resolution mass spectrometry.

J Pharm Biomed Anal 2018 May 6;154:66-74. Epub 2018 Mar 6.

Department of Molecular Sciences, Macquarie University, Sydney, Australia; Australian Proteome Analysis Facility, Macquarie University, Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2018.03.012DOI Listing
May 2018

Polyphenol extracts from dried sugarcane inhibit inflammatory mediators in an in vitro colon cancer model.

J Proteomics 2018 04 10;177:1-10. Epub 2018 Feb 10.

Australian Research Council Industrial Transformation Training Centre for Molecular Technology in the Food Industry, Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, Australia; Australian Proteome Analysis Facility, Macquarie University, Sydney, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S18743919183005
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http://dx.doi.org/10.1016/j.jprot.2018.02.009DOI Listing
April 2018

SWATH Mass Spectrometry for Proteomics of Non-Depleted Plasma.

Methods Mol Biol 2017 ;1619:373-383

Department of Chemistry and Biomolecular Sciences, Australian Proteome Analysis Facility (APAF), Macquarie University, E8C310, Research Park Drive, Sydney, NSW, 2109, Australia.

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http://dx.doi.org/10.1007/978-1-4939-7057-5_25DOI Listing
March 2018

TMT One-Stop Shop: From Reliable Sample Preparation to Computational Analysis Platform.

Methods Mol Biol 2017 ;1549:45-66

Faculty of Medicine and Health Sciences, Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, NSW, 2109, Australia.

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http://dx.doi.org/10.1007/978-1-4939-6740-7_5DOI Listing
February 2018

Development of a data independent acquisition mass spectrometry workflow to enable glycopeptide analysis without predefined glycan compositional knowledge.

J Proteomics 2018 02 22;172:68-75. Epub 2017 Oct 22.

Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney 2109, Australia; Australian Proteome Analysis Facility, Macquarie University, Sydney 2109, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2017.10.011DOI Listing
February 2018

Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy.

Cell Mol Life Sci 2018 01 29;75(2):335-354. Epub 2017 Aug 29.

Centre for Motor Neuron Disease Research, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, 2 Technology Place, North Ryde, NSW, 2109, Australia.

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http://dx.doi.org/10.1007/s00018-017-2632-8DOI Listing
January 2018

Pseudomonas aeruginosa Proteome under Hypoxic Stress Conditions Mimicking the Cystic Fibrosis Lung.

J Proteome Res 2017 10 31;16(10):3917-3928. Epub 2017 Aug 31.

Department of Chemistry and Biomolecular Sciences, Macquarie University , Sydney 2109, Australia.

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http://dx.doi.org/10.1021/acs.jproteome.7b00561DOI Listing
October 2017

Improving Protein Detection Confidence Using SWATH-Mass Spectrometry with Large Peptide Reference Libraries.

Proteomics 2017 Oct;17(19)

Australian Proteome Analysis Facility (APAF), Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.1002/pmic.201700174DOI Listing
October 2017

Plasma biomarker proteins for detection of human growth hormone administration in athletes.

Sci Rep 2017 08 30;7(1):10039. Epub 2017 Aug 30.

Australian Proteome Analysis Facility (APAF), Level 4, Building F7B, Research Park Drive, Macquarie University, Sydney, NSW 2109, Australia.

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http://dx.doi.org/10.1038/s41598-017-09968-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5577294PMC
August 2017

Quantitative Age-specific Variability of Plasma Proteins in Healthy Neonates, Children and Adults.

Mol Cell Proteomics 2017 05 23;16(5):924-935. Epub 2017 Mar 23.

From the ‡Hematology Research Laboratory, Murdoch Childrens Research Institute, Melbourne, VIC 3052, Australia;

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http://dx.doi.org/10.1074/mcp.M116.066720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417830PMC
May 2017

Identification of protein targets in cerebral endothelial cells for brain arteriovenous malformation (AVMs) molecular therapies.

Clin Proteomics 2017 16;14:17. Epub 2017 May 16.

Department of Clinical Medicine, Faculty of Medicine and Health Sciences, Macquarie University, North Ryde, NSW 2109 Australia.

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http://dx.doi.org/10.1186/s12014-017-9151-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434588PMC
May 2017

Ionizing radiation reduces ADAM10 expression in brain microvascular endothelial cells undergoing stress-induced senescence.

Aging (Albany NY) 2017 04;9(4):1248-1268

Department of Clinical Medicine, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, New South Wales, 2109, Australia.

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http://dx.doi.org/10.18632/aging.101225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425125PMC
April 2017

Unravelling the role of protein kinase CK2 in metal toxicity using gene deletion mutants.

Metallomics 2017 03;9(3):301-308

School of Science and Health, Western Sydney University, Locked Bag 1797, Penrith, NSW 2751, Australia. and Molecular Medicine Research Group, School of Medicine, Western Sydney University, Locked Bag 1797, Penrith, NSW 2751, Australia.

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http://dx.doi.org/10.1039/c6mt00230gDOI Listing
March 2017

Radiosurgery Alters the Endothelial Surface Proteome: Externalized Intracellular Molecules as Potential Vascular Targets in Irradiated Brain Arteriovenous Malformations.

Radiat Res 2017 01 5;187(1):66-78. Epub 2017 Jan 5.

a   Department of Clinical Medicine, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1667/RR14518.1DOI Listing
January 2017

Analytical performance of nano-LC-SRM using nondepleted human plasma over an 18-month period.

Proteomics 2016 08 25;16(15-16):2118-27. Epub 2016 Jul 25.

Australian Proteome Analysis Facility, Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.1002/pmic.201500507DOI Listing
August 2016

Changes in the in vitro activity of platinum drugs when administered in two aliquots.

BMC Cancer 2016 08 26;16:688. Epub 2016 Aug 26.

Discipline of Biomedical Science, Sydney Medical School, University of Sydney, Sydney, NSW, 2141, Australia.

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http://dx.doi.org/10.1186/s12885-016-2731-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5002105PMC
August 2016

SWATH Mass Spectrometry Performance Using Extended Peptide MS/MS Assay Libraries.

Mol Cell Proteomics 2016 07 9;15(7):2501-14. Epub 2016 May 9.

From the ‡Australian Proteome Analysis Facility (APAF), Dept. Chemistry & Biomolecular Sciences, Macquarie University, Sydney, Australia

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http://www.mcponline.org/lookup/doi/10.1074/mcp.M115.055558
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http://dx.doi.org/10.1074/mcp.M115.055558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937520PMC
July 2016

Pseudomonas aeruginosa Cell Membrane Protein Expression from Phenotypically Diverse Cystic Fibrosis Isolates Demonstrates Host-Specific Adaptations.

J Proteome Res 2016 07 9;15(7):2152-63. Epub 2016 Jun 9.

Department of Chemistry and Biomolecular Sciences, Macquarie University , Sydney, New South Wales 2109, Australia.

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http://dx.doi.org/10.1021/acs.jproteome.6b00058DOI Listing
July 2016

Exhaled breath condensate for lung cancer protein analysis: a review of methods and biomarkers.

J Breath Res 2016 07 5;10(3):034001. Epub 2016 Jul 5.

Bill Walsh Translational Cancer Research Laboratory, Kolling Institute of Medical Research, Northern Sydney Local Health District, St. Leonards, New South Wales, Australia. Sydney Medical School Northern, University of Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1088/1752-7155/10/3/034001DOI Listing
July 2016

CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia.

Nat Commun 2016 Apr 15;7:11253. Epub 2016 Apr 15.

Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, New South Wales 2109, Australia.

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http://dx.doi.org/10.1038/ncomms11253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835537PMC
April 2016

Priming Adipose-Derived Mesenchymal Stem Cells with Hyaluronan Alters Growth Kinetics and Increases Attachment to Articular Cartilage.

Stem Cells Int 2016 15;2016:9364213. Epub 2016 Feb 15.

Translational Regenerative Medicine Research Laboratory, Kolling Institute of Medical Research, Institute of Bone and Joint Research, University of Sydney at Royal North Shore Hospital, St Leonards, NSW 2065, Australia; Regeneus Ltd., 25 Bridge Street, Pymble, NSW 2073, Australia.

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http://dx.doi.org/10.1155/2016/9364213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770159PMC
March 2016

Proteomics of thyroid tumours provides new insights into their molecular composition and changes associated with malignancy.

Sci Rep 2016 Mar 30;6:23660. Epub 2016 Mar 30.

Department of Chemistry and Biomolecular Sciences, Macquarie University, NSW 2109, Australia.

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http://dx.doi.org/10.1038/srep23660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812243PMC
March 2016

Characterization of a beta-catenin nuclear localization defect in MCF-7 breast cancer cells.

Exp Cell Res 2016 Feb 1;341(2):196-206. Epub 2016 Feb 1.

Centre for Cancer Research, The Westmead Institute for Medical Research, The University of Sydney, Westmead, NSW 2145, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2016.01.020DOI Listing
February 2016

Reporting in studies of protein biomarkers of prognosis in colorectal cancer in relation to the REMARK guidelines.

Proteomics Clin Appl 2015 Dec 7;9(11-12):1078-86. Epub 2015 May 7.

Department of Medical Oncology, Royal North Shore Hospital, The University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.1002/prca.201400177DOI Listing
December 2015

Fetuin B Is a Secreted Hepatocyte Factor Linking Steatosis to Impaired Glucose Metabolism.

Cell Metab 2015 Dec 22;22(6):1078-89. Epub 2015 Oct 22.

Monash Biomedicine Discovery Institute, Metabolic Disease and Obesity Program, and Biology of Lipid Metabolism Laboratory, Department of Physiology, Monash University, Clayton, VIC 3800, Australia. Electronic address:

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http://www.cell.com/cell-metabolism/pdf/S1550-4131(15)00480-
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http://linkinghub.elsevier.com/retrieve/pii/S155041311500480
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http://dx.doi.org/10.1016/j.cmet.2015.09.023DOI Listing
December 2015

Online Peptide fractionation using a multiphasic microfluidic liquid chromatography chip improves reproducibility and detection limits for quantitation in discovery and targeted proteomics.

Mol Cell Proteomics 2015 Jun 7;14(6):1708-19. Epub 2015 Apr 7.

From the ‡Australian Proteome Analysis Facility (APAF), Department of Chemistry and Biomolecular Sciences, Macquarie University, 2109, Sydney, Australia;

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http://dx.doi.org/10.1074/mcp.M114.046425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458731PMC
June 2015

The mannose-6-phosphate analogue, PXS64, inhibits fibrosis via TGF-β1 pathway in human lung fibroblasts.

Immunol Lett 2015 Jun 27;165(2):90-101. Epub 2015 Apr 27.

Drug Discovery, Pharmaxis, Australia; School of Medical & Molecular Biosciences, University of Technology Sydney, Australia.

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http://dx.doi.org/10.1016/j.imlet.2015.04.003DOI Listing
June 2015

Phosphoproteomic Analysis of Cell-Based Resistance to BRAF Inhibitor Therapy in Melanoma.

Front Oncol 2015 15;5:95. Epub 2015 May 15.

Australian Proteome Analysis Facility, Department of Chemistry and Biomolecular Sciences, Macquarie University , Sydney, NSW , Australia.

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http://dx.doi.org/10.3389/fonc.2015.00095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432663PMC
June 2015

A multiplexed, targeted mass spectrometry assay of the S100 protein family uncovers the isoform-specific expression in thyroid tumours.

BMC Cancer 2015 Mar 29;15:199. Epub 2015 Mar 29.

Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, NSW, 2109, Australia.

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http://dx.doi.org/10.1186/s12885-015-1217-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391164PMC
March 2015

Proteomics of hosts and pathogens in cystic fibrosis.

Proteomics Clin Appl 2015 Feb 19;9(1-2):134-46. Epub 2015 Jan 19.

Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.1002/prca.201400122DOI Listing
February 2015

Combining protein ratio p-values as a pragmatic approach to the analysis of multirun iTRAQ experiments.

J Proteome Res 2015 Feb 13;14(2):738-46. Epub 2015 Jan 13.

Australian Proteome Analysis Facility, Macquarie University , Sydney, NSW 2109, Australia.

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http://dx.doi.org/10.1021/pr501091eDOI Listing
February 2015

Multidimensional fractionation is a requirement for quantitation of Golgi-resident glycosylation enzymes from cultured human cells.

J Proteome Res 2015 Feb 24;14(2):747-55. Epub 2014 Dec 24.

Department of Chemistry and Biomolecular Sciences, Faculty of Science, and ‡Australian Proteome Analysis Facility, Macquarie University , Sydney, Australia.

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http://dx.doi.org/10.1021/pr500785fDOI Listing
February 2015

Comprehensive glycomics comparison between colon cancer cell cultures and tumours: implications for biomarker studies.

J Proteomics 2014 Aug 17;108:146-62. Epub 2014 May 17.

Department of Chemistry and Biomolecular Sciences, Faculty of Science, Macquarie University, Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2014.05.002DOI Listing
August 2014

The necrotrophic effector protein SnTox3 re-programs metabolism and elicits a strong defence response in susceptible wheat leaves.

BMC Plant Biol 2014 Aug 15;14:215. Epub 2014 Aug 15.

Plant Sciences Division, Research School of Biology, The Australian National University, Canberra 0200, ACT, Australia.

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http://dx.doi.org/10.1186/s12870-014-0215-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243954PMC
August 2014

Phosphoproteomics of MAPK inhibition in BRAF-mutated cells and a role for the lethal synergism of dual BRAF and CK2 inhibition.

Mol Cancer Ther 2014 Jul 13;13(7):1894-906. Epub 2014 May 13.

Authors' Affiliations: Australian Proteome Analysis Facility, Department of Chemistry and Biomolecular Sciences, Macquarie University; and

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http://dx.doi.org/10.1158/1535-7163.MCT-13-0938DOI Listing
July 2014

Stoichiometry of Saccharomyces cerevisiae lysine methylation: insights into non-histone protein lysine methyltransferase activity.

J Proteome Res 2014 Mar 21;13(3):1744-56. Epub 2014 Feb 21.

NSW Systems Biology Initiative, University of New South Wales , Sydney, New South Wales 2052, Australia.

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http://dx.doi.org/10.1021/pr401251kDOI Listing
March 2014

From mice to men: GEMMs as trial patients for new NSCLC therapies.

Semin Cell Dev Biol 2014 Mar 6;27:118-27. Epub 2014 Apr 6.

Bill Walsh Translational Cancer Research Laboratory, Kolling Institute of Medical Research, University of Sydney, Royal North Shore Hospital, St. Leonards, New South Wales, Australia; Department of Medical Oncology, Royal North Shore Hospital, University of Sydney, St. Leonards, New South Wales, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2014.04.002DOI Listing
March 2014

Coverage and consistency: bioinformatics aspects of the analysis of multirun iTRAQ experiments with wheat leaves.

J Proteome Res 2013 Nov 20;12(11):4870-81. Epub 2013 Sep 20.

Australian Proteome Analysis Facility, Macquarie University , Sydney, NSW 2109, Australia.

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http://dx.doi.org/10.1021/pr400531yDOI Listing
November 2013

Proteome analysis reveals antiangiogenic environments in chronic wounds of diabetes mellitus type 2 patients.

Proteomics 2013 Sep 30;13(17):2670-81. Epub 2013 Jul 30.

Department of Analytical Chemistry, Biomolecular Mass Spectrometry, Ruhr-University Bochum, Bochum, Germany; Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.1002/pmic.201200502DOI Listing
September 2013

Label-free selected reaction monitoring enables multiplexed quantitation of S100 protein isoforms in cancer cells.

J Proteome Res 2013 Aug 3;12(8):3679-88. Epub 2013 Jul 3.

Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.1021/pr400251tDOI Listing
August 2013

Tandem ion exchange fractionation of chicken egg white reveals the presence of proliferative bioactivity.

J Agric Food Chem 2013 May 19;61(17):4079-88. Epub 2013 Apr 19.

Department of Chemistry and Biomolecular Sciences and ‡Australian Proteome Analysis Facility (APAF), Research Park Drive, Macquarie University , Sydney, 2109 NSW, Australia.

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http://dx.doi.org/10.1021/jf305276cDOI Listing
May 2013

Two-stepping to increase peptide spectra matches in large databases.

Authors:
Mark P Molloy

Proteomics 2013 Apr;13(8):1229-30

Australian Proteome Analysis Facility, Department Chemistry & Biomolecular Sciences, Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.1002/pmic.201300094DOI Listing
April 2013

Quantitative mass spectrometry for colorectal cancer proteomics.

Proteomics Clin Appl 2013 Jan;7(1-2):42-54

Australian Proteome Analysis Facility (APAF), Department of Chemistry & Biomolecular Sciences, Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.1002/prca.201200080DOI Listing
January 2013

Remarkable temporal stability of high-abundance human plasma proteins assessed by targeted mass spectrometry.

Proteomics Clin Appl 2012 Dec 8;6(11-12):626-34. Epub 2012 Nov 8.

Department of Chemistry & Biomolecular Sciences, Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.1002/prca.201200039DOI Listing
December 2012

An iTRAQ proteomics screen reveals the effects of the MDM2 binding ligand Nutlin-3 on cellular proteostasis.

J Proteome Res 2012 Nov 18;11(11):5464-78. Epub 2012 Oct 18.

Cell Signalling Unit, p53 Signal Transduction Laboratories, Edinburgh Cancer Research Centre, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, United Kingdom.

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http://dx.doi.org/10.1021/pr300698dDOI Listing
November 2012

Why complexity and entropy matter: information, posttranslational modifications, and assay fidelity.

Proteomics 2012 Apr;12(8):1147-50

Department of Pharmaceutical Chemistry, UCSF, San Francisco, CA, USA.

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http://dx.doi.org/10.1002/pmic.201100459DOI Listing
April 2012

Multidimensional protein identification technology-selected reaction monitoring improving detection and quantification for protein biomarker studies.

Anal Chem 2012 Feb 24;84(3):1592-600. Epub 2012 Jan 24.

Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.1021/ac2028485DOI Listing
February 2012

Classification of cancer patients using pathway analysis and network clustering.

Methods Mol Biol 2011 ;781:311-36

School of Biotechnology and Biomolecular Sciences, New South Wales Systems Biology Initiative, The University of New South Wales, Sydney, NSW, Australia.

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http://dx.doi.org/10.1007/978-1-61779-276-2_15DOI Listing
January 2012

Specific armadillo repeat sequences facilitate β-catenin nuclear transport in live cells via direct binding to nucleoporins Nup62, Nup153, and RanBP2/Nup358.

J Biol Chem 2012 Jan 21;287(2):819-31. Epub 2011 Nov 21.

Westmead Institute for Cancer Research, The University of Sydney, Westmead, New South Wales 2145, Australia.

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http://dx.doi.org/10.1074/jbc.M111.299099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256910PMC
January 2012

Mutated in colorectal cancer protein modulates the NFκB pathway.

Anticancer Res 2012 Jan;32(1):73-9

Cancer Research Program, Garvan Institute of Medical Research, 384 Victoria Street, Sydney NSW 2010, Australia.

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January 2012

Towards clinical applications of selected reaction monitoring for plasma protein biomarker studies.

Proteomics Clin Appl 2012 Jan 27;6(1-2):42-59. Epub 2011 Dec 27.

Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.1002/prca.201100062DOI Listing
January 2012

Proteomic comparison of colorectal tumours and non-neoplastic mucosa from paired patient samples using iTRAQ mass spectrometry.

Mol Biosyst 2011 Nov 2;7(11):2997-3005. Epub 2011 Aug 2.

Cancer Pharmacology Unit, ANZAC Research Institute and Discipline of Medicine, The University of Sydney, Sydney, Australia.

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http://dx.doi.org/10.1039/c1mb05236eDOI Listing
November 2011

Quantitative phosphoproteomics of transforming growth factor-β signaling in colon cancer cells.

Proteomics 2011 Aug;11(16):3390-401

Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.1002/pmic.201100036DOI Listing
August 2011

Quantitative chemical proteomics in small-scale culture of phorbol ester stimulated basal breast cancer cells.

Proteomics 2011 Jul 31;11(13):2683-92. Epub 2011 May 31.

Department of Chemistry and Biomolecular Sciences, Faculty of Science, Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.1002/pmic.201000801DOI Listing
July 2011

Proteomics of Smad4 regulated transforming growth factor-beta signalling in colon cancer cells.

Mol Biosyst 2010 Nov 22;6(11):2332-8. Epub 2010 Sep 22.

Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.1039/c0mb00016gDOI Listing
November 2010

Evaluation of blood collection tubes using selected reaction monitoring MS: implications for proteomic biomarker studies.

Proteomics 2010 May;10(10):2050-6

Department of Chemistry & Biomolecular Sciences, Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.1002/pmic.200900517DOI Listing
May 2010

Clinicopathological correlates and prognostic significance of maspin expression in 450 patients after potentially curative resection of node-positive colonic cancer.

Histopathology 2010 Feb;56(3):319-30

Department of Anatomical Pathology, Concord Hospital, and Discipline of Pathology, The University of Sydney, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1111/j.1365-2559.2010.03479.xDOI Listing
February 2010

High-abundance protein depletion: comparison of methods for human plasma biomarker discovery.

Electrophoresis 2010 Jan;31(3):471-82

Department of Chemistry and Biomolecular Sciences, Macquarie University, NSW, Australia.

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http://dx.doi.org/10.1002/elps.200900286DOI Listing
January 2010

Identification of distinctive protein expression patterns in colorectal adenoma.

Proteomics Clin Appl 2010 Jan 3;4(1):60-70. Epub 2009 Nov 3.

Department of Colorectal Surgery, Concord Hospital and Discipline of Surgery, The University of Sydney, NSW Australia.

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http://dx.doi.org/10.1002/prca.200900084DOI Listing
January 2010

Unique ion signature mass spectrometry, a deterministic method to assign peptide identity.

Mol Cell Proteomics 2009 Sep 25;8(9):2051-62. Epub 2009 Jun 25.

Australian Proteome Analysis Facility, Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney 2109, Australia.

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http://dx.doi.org/10.1074/mcp.M800512-MCP200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742438PMC
September 2009

Recent progress in selected reaction monitoring MS-driven plasma protein biomarker analysis.

Bioanalysis 2009 Jul;1(4):847-55

Department of Chemistry & Biomolecular Sciences and Australian Proteome Analysis Facility, Macquarie University, Sydney 2109, Australia.

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http://dx.doi.org/10.4155/bio.09.56DOI Listing
July 2009

How specific is my SRM?: The issue of precursor and product ion redundancy.

Proteomics 2009 Mar;9(5):1120-3

Department of Chemistry and Biomolecular Sciences, Australian Proteome Analysis Facility, Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.1002/pmic.200800577DOI Listing
March 2009

A longitudinal study of the protein components of marsupial milk from birth to weaning in the tammar wallaby (Macropus eugenii).

Dev Comp Immunol 2009 Feb 7;33(2):152-61. Epub 2008 Sep 7.

Department of Biological Science, Division of Environmental and Life Sciences, Macquarie University, Sydney, NSW, Australia.

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http://dx.doi.org/10.1016/j.dci.2008.08.002DOI Listing
February 2009

Differential proteome expression associated with urokinase plasminogen activator receptor (uPAR) suppression in malignant epithelial cancer.

J Proteome Res 2008 Nov 23;7(11):4792-806. Epub 2008 Sep 23.

Department of Chemistry and Biomolecular Sciences and Australian Proteome Analysis Facility, Macquarie University, Sydney, NSW 2109, Australia.

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http://dx.doi.org/10.1021/pr800357hDOI Listing
November 2008

iTRAQ experimental design for plasma biomarker discovery.

J Proteome Res 2008 Jul 13;7(7):2952-8. Epub 2008 Jun 13.

Australian Proteome Analysis Facility Ltd., Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.1021/pr800072xDOI Listing
July 2008

Isolation of bacterial cell membranes proteins using carbonate extraction.

Authors:
Mark P Molloy

Methods Mol Biol 2008 ;424:397-401

Australian Proteome Analysis Facility Ltd., Sydney, Australia.

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http://dx.doi.org/10.1007/978-1-60327-064-9_30DOI Listing
May 2008

Angiotensin II-inducible platelet-derived growth factor-D transcription requires specific Ser/Thr residues in the second zinc finger region of Sp1.

Circ Res 2008 Feb 7;102(4):e38-51. Epub 2008 Feb 7.

Centre for Vascular Research, School of Medical Sciences, University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1161/CIRCRESAHA.107.167395DOI Listing
February 2008

The development of multiple reaction monitoring assays for liver-derived plasma proteins.

Proteomics Clin Appl 2007 Dec 16;1(12):1570-81. Epub 2007 Nov 16.

Australian Proteome Analysis Facility Ltd (APAF), Macquarie University, Sydney, Australia; Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, Australia.

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http://dx.doi.org/10.1002/prca.200700305DOI Listing
December 2007