Mark Mirochnick

Mark Mirochnick

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Mark Mirochnick

Publications by authors named "Mark Mirochnick"

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82Publications

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Darunavir Pharmacokinetics With an Increased Dose During Pregnancy.

J Acquir Immune Defic Syndr 2020 Apr;83(4):373-380

Department of Clinical Pharmacy and Pediatrics, University of California San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, CA.

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http://dx.doi.org/10.1097/QAI.0000000000002261DOI Listing
April 2020

Prediction of dolutegravir pharmacokinetics and dose optimization in neonates via physiologically based pharmacokinetic (PBPK) modelling.

J Antimicrob Chemother 2020 Mar;75(3):640-647

Department of Molecular and Clinical Pharmacology, University of Liverpool, 70 Pembroke Place, Liverpool L69 3GF, UK.

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http://dx.doi.org/10.1093/jac/dkz506DOI Listing
March 2020

Fosamprenavir with Ritonavir Pharmacokinetics during Pregnancy.

Antimicrob Agents Chemother 2020 Mar 24;64(4). Epub 2020 Mar 24.

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1128/AAC.02260-19DOI Listing
March 2020

Tenofovir alafenamide use in pregnant and lactating women living with HIV.

Expert Opin Drug Metab Toxicol 2020 Mar 17:1-10. Epub 2020 Mar 17.

Division of Neonatology, Department of Pediatrics, Boston University School of Medicine, Boston, MA, USA.

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http://dx.doi.org/10.1080/17425255.2020.1738384DOI Listing
March 2020

Physiologically Based Pharmacokinetic Models to Predict Maternal Pharmacokinetics and Fetal Exposure to Emtricitabine and Acyclovir.

J Clin Pharmacol 2020 Feb 6;60(2):240-255. Epub 2019 Sep 6.

Pediatric Pharmacology and Pharmacometrics Research Center, University Children's Hospital Basel (UKBB), Basel, Switzerland.

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http://dx.doi.org/10.1002/jcph.1515DOI Listing
February 2020

Importance of Prospective Studies in Pregnant and Breastfeeding Women Living With Human Immunodeficiency Virus.

Clin Infect Dis 2019 Sep;69(7):1254-1258

Department of Pharmacy, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1093/cid/ciz121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743813PMC
September 2019

Improving Respiratory Support Practices to Reduce Chronic Lung Disease in Premature Infants.

Pediatr Qual Saf 2019 Jul-Aug;4(4):e193. Epub 2019 Aug 9.

Department of Pediatric Newborn Medicine, Brigham and Women's Hospital, Boston, Mass.

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http://dx.doi.org/10.1097/pq9.0000000000000193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708652PMC
August 2019

Ritonavir and cobicistat as pharmacokinetic enhancers in pregnant women.

Expert Opin Drug Metab Toxicol 2019 Jul 11;15(7):523-525. Epub 2019 Jun 11.

c Division of Neonatology, Department of Pediatrics , Boston University School of Medicine , Boston , MA , USA.

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http://dx.doi.org/10.1080/17425255.2019.1628947DOI Listing
July 2019

Cobicistat as a Pharmacoenhancer in Pregnancy and Postpartum: Progress to Date and Next Steps.

J Clin Pharmacol 2019 Jun 1;59(6):779-783. Epub 2019 Mar 1.

Division of Neonatology, Department of Pediatrics, Boston University School of Medicine, Boston, MA, USA.

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http://dx.doi.org/10.1002/jcph.1397DOI Listing
June 2019

Pharmacokinetics of Increased Nelfinavir Plasma Concentrations in Women During Pregnancy and Postpartum.

J Clin Pharmacol 2019 03 25;59(3):386-393. Epub 2018 Oct 25.

Division of Maternal Fetal Medicine, Department of Gynecology & Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/jcph.1331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368469PMC
March 2019

Efavirenz pharmacokinetics during pregnancy and infant washout.

Antivir Ther 2019 ;24(2):95-103

Departments of Pharmacy and Pharmacology and Toxicology, Radboud University Medical Center, Nijmegen, the Netherlands.

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http://dx.doi.org/10.3851/IMP3283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642905PMC
January 2019

In Vitro Study on the Effect of Maraviroc or Dolutegravir on Bilirubin to Albumin Binding.

Pediatr Infect Dis J 2018 09;37(9):908-909

Department of Pediatrics, Boston Medical Center, Boston, Massachusetts.

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http://dx.doi.org/10.1097/INF.0000000000002011DOI Listing
September 2018

Prevention and treatment of HIV infection in neonates: evidence base for existing WHO dosing recommendations and implementation considerations.

Expert Rev Clin Pharmacol 2018 Jan 8;11(1):83-93. Epub 2017 Nov 8.

b Department of Pediatrics , Boston University School of Medicine , Boston , MA , USA.

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http://dx.doi.org/10.1080/17512433.2018.1393331DOI Listing
January 2018

Praziquantel for the treatment of schistosomiasis during human pregnancy.

Bull World Health Organ 2018 Jan 27;96(1):59-65. Epub 2017 Nov 27.

Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, England.

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http://dx.doi.org/10.2471/BLT.17.198879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791873PMC
January 2018

Bone Age and Mineral Density Assessments Using Plain Roentgenograms in Tenofovir-exposed Infants in Malawi and Brazil Enrolled in HIV Prevention Trials Network 057.

Pediatr Infect Dis J 2017 02;36(2):184-188

From the *Department of Pediatrics, David Geffen UCLA School of Medicine, Los Angeles, California; †Department of Pediatrics, Boston University School of Medicine, Boston, Massachusetts; ‡Department of Medicine, Malawi College of Medicine, Blantyre, Malawi; §Department of Obstetrics and Gynecology, Santa Casa de Misericordia, Porto Alegre, Brazil; ¶SCHARP Fred Hutchinson Cancer Research Center, Seattle, Washington; ‖Department of Pediatrics, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; **Department of Infectious Diseases, Hospital Federal dos Servidores do Estado, Rio de Janeiro, Brazil; ††Department of Infectious Diseases, Hospital Conceicao, Porto Alegre, Brazil; ‡‡Family Health International, Durham, North Carolina; §§National Institute of Allergy and Infectious Diseases, and ¶¶Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1097/INF.0000000000001386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233548PMC
February 2017

Pharmacokinetics of Rilpivirine in HIV-Infected Pregnant Women.

J Acquir Immune Defic Syndr 2016 07;72(3):289-96

*Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, CA; †Skaggs School of Pharmacy and Pharmaceutical Sciences, Pediatrics Department-Rady Children's Hospital, University of California, San Diego, CA; ‡Department of Obstetrics and Gynecology, University of Southern California, Los Angeles, CA; §Department of Biostatistics, Harvard School of Public Health, Boston, MA; ‖Department of Medicine, Children's Hospital Boston, Boston, MA; ¶Irmandade da Santa Casa de Misericordia de Porto Alegre, HIV/AIDS Research Department, Porto Alegre, Brazil; #Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand; **FHI 360, IMPAACT Operations Office, Durham, NC; ††Program for HIV Prevention and Treatment, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; ‡‡Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Health, DHHS, Bethesda, MD; §§National Institute of Allergy and Infectious Diseases, Bethesda, MD; and ‖‖Department of Pediatrics, Boston University School of Medicine, Boston, MA.

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http://dx.doi.org/10.1097/QAI.0000000000000968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911231PMC
July 2016

Pharmacokinetics of Once Versus Twice Daily Darunavir in Pregnant HIV-Infected Women.

J Acquir Immune Defic Syndr 2015 Sep;70(1):33-41

*Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, University of Southern California School of Medicine, Los Angeles, CA; †Department of Biostatistics, Statistical and Data Analysis Center, Harvard School of Public Health, Boston, MA; ‡Department of Medicine, Children's Hospital Boston, Boston, MA; §HIV/AIDS Research Department, Irmandade da Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Brazil; ‖Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand; ¶Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; #Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, DHHS, Bethesda, MD; **National Institute of Allergy and Infectious Diseases, Bethesda, MD; and ††Department of Pediatrics, Boston University School of Medicine, Boston, MA.

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http://dx.doi.org/10.1097/QAI.0000000000000668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579345PMC
September 2015

Raltegravir pharmacokinetics during pregnancy.

J Acquir Immune Defic Syndr 2014 Dec;67(4):375-81

*Office of the Global AIDS Coordinator, U.S. Department of State, Washington, DC; †Department of Obstetrics and Gynecology, University of Southern California School of Medicine, Los Angeles, CA; ‡Department of Pediatrics and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, CA; §Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, MA; ‖Program for HIV Prevention and Treatment (IRD URI 174), Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; ¶Department of Clinical Pharmacy, Drug Research Unit, University of California, San Francisco, San Francisco, CA; #HIV/AIDS Research Department, Irmandade da Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Brazil; **Boston Children's Hospital, Harvard Medical School, Boston, MA; ††Social and Scientific Systems, Inc, Silver Spring, MD; ‡‡Maternal, Adolescent, and Pediatric Research Branch, National Institute of Allergy and Infectious Diseases, Bethesda, MD; and §§Department of Pediatrics, Boston University School of Medicine, Boston, MA.

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http://dx.doi.org/10.1097/QAI.0000000000000318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213295PMC
December 2014

Designing drug trials: considerations for pregnant women.

Clin Infect Dis 2014 Dec;59 Suppl 7:S437-44

Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda.

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http://dx.doi.org/10.1093/cid/ciu709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303056PMC
December 2014

Raltegravir pharmacokinetics in neonates following maternal dosing.

J Acquir Immune Defic Syndr 2014 Nov;67(3):310-5

*Section of Pediatric Infectious Diseases, Boston Medical Center, Boston, MA; †Division of Clinical Pharmacology, University of Alabama at Birmingham, Birmingham, AL; ‡Merck & Co., Inc., Whitehouse Station, NJ; §Department of Pediatric Infectious Diseases, David Geffen School of Medicine at University of California at Los Angeles, Los Angeles, CA; ‖Department of Pediatrics, University of California, San Diego and Rady Children's Hospital San Diego, La Jolla, CA; ¶Eunice Kennedy Shriver National Institute of Child Health and Human Development, #Division of AIDS, National Institute of Health, Bethesda, MD; **Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD; ††Statistical and Data Analysis Center, Harvard School of Public Health, Boston, MA; and ‡‡Department of Pediatrics, Boston University School of Medicine, Boston, MA.

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http://dx.doi.org/10.1097/QAI.0000000000000316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197108PMC
November 2014

Pharmacokinetics and safety of tenofovir in HIV-infected women during labor and their infants during the first week of life.

J Acquir Immune Defic Syndr 2014 Jan;65(1):33-41

*Department of Pediatrics, Boston University School of Medicine, Boston, MA; †Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD; ‡HIV/AIDS Research Department, Irmandade da Santa Casa de Misericordia de Porto Alegre, Rio Grande do Sul, Brazil; §Department of Pediatrics, David Geffen UCLA School of Medicine, Los Angeles, CA; ‖Malawi College of Medicine, Blantyre, Malawi; ¶Infectious Diseases Department, Hospital Federal dos Servidores do Estado, Rio de Janiero, Brazil; #Department of Pediatrics, School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; **Serviço de Infectologia, Hospital Nossa Senhora da Conceicao, Porto Alegre, Rio Grande do Sul, Brazil; ††Division of Clinical Pharmacology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD; ‡‡Gilead Sciences, Foster City, CA; §§Statistical Center for HIV/AIDS Research and Prevention, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA; ‖‖Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD; ¶¶Family Health International, Durham, NC; ##Makerere University-Johns Hopkins University Research Collaboration, Kampala, Uganda; ***National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD; and †††Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Rockville, MD.

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http://dx.doi.org/10.1097/QAI.0b013e3182a921ebDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912736PMC
January 2014

Reduced indinavir exposure during pregnancy.

Br J Clin Pharmacol 2013 Sep;76(3):475-83

Program for HIV Prevention and Treatment (IRD URI 174), Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; Harvard School of Public Health, Boston, MA, USA; Institut de Recherché pour le Développement (IRD), UMI 174-PHPT, Marseille, France.

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http://doi.wiley.com/10.1111/bcp.12078
Publisher Site
http://dx.doi.org/10.1111/bcp.12078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769674PMC
September 2013

Raltegravir in vitro effect on bilirubin binding.

Pediatr Infect Dis J 2013 Sep;32(9):978-80

From the *Department of Pediatrics, Boston University School of Medicine/Boston Medical Center, Boston, MA; †Department of Pediatrics, Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Stanford, CA; and ‡Merck & Co., Inc., Whitehouse Station, NJ.

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http://dx.doi.org/10.1097/INF.0b013e31829044a8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856729PMC
September 2013

Developmental pharmacokinetic changes of Lamivudine in infants and children.

J Clin Pharmacol 2012 Dec 16;52(12):1824-32. Epub 2011 Dec 16.

UC San Diego Pediatric Research Center, 7910 Frost St, #360, San Diego, CA 92123, USA.

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http://dx.doi.org/10.1177/0091270011426563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369109PMC
December 2012

Efavirenz pharmacokinetics during the third trimester of pregnancy and postpartum.

J Acquir Immune Defic Syndr 2012 Mar;59(3):245-52

Program for HIV Prevention and Treatment (IRD URI 174), Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.

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http://dx.doi.org/10.1097/QAI.0b013e31823ff052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288559PMC
March 2012

Targeted echocardiography in the neonatal intensive care unit.

J Am Soc Echocardiogr 2012 Mar 31;25(3):361; author reply 361-2. Epub 2012 Jan 31.

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http://dx.doi.org/10.1016/j.echo.2012.01.001DOI Listing
March 2012

Oseltamivir pharmacokinetics in pregnancy: a commentary.

Am J Obstet Gynecol 2011 Jun 23;204(6 Suppl 1):S94-5. Epub 2011 Feb 23.

Department of Pediatrics, Boston Medical Center and Boston University School of Medicine, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.ajog.2011.02.043DOI Listing
June 2011

Antiretroviral pharmacology: special issues regarding pregnant women and neonates.

Clin Perinatol 2010 Dec;37(4):907-27, xi

Division of Neonatology, Department of Pediatrics, Boston University School of Medicine, 771 Albany Street - Dowling 4111, Boston, MA 02118, USA.

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http://dx.doi.org/10.1016/j.clp.2010.08.006DOI Listing
December 2010

Lopinavir tablet pharmacokinetics with an increased dose during pregnancy.

J Acquir Immune Defic Syndr 2010 Aug;54(4):381-8

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, San Diego, CA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265163PMC
http://dx.doi.org/10.1097/qai.0b013e3181d6c9edDOI Listing
August 2010

Zidovudine, lamivudine, and nelfinavir concentrations in amniotic fluid and maternal serum.

HIV Clin Trials 2009 Jan-Feb;10(1):41-7

Division of Clinical Pharmacology, University of Alabama at Birmingham School of Medicine, Birmingham, AL 35294-0019, USA.

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http://dx.doi.org/10.1310/hct1001-041DOI Listing
July 2009

Antiretroviral concentrations in breast-feeding infants of mothers receiving highly active antiretroviral therapy.

Antimicrob Agents Chemother 2009 Mar 29;53(3):1170-6. Epub 2008 Dec 29.

Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts 02118, USA.

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http://dx.doi.org/10.1128/AAC.01117-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650559PMC
March 2009

Lopinavir exposure with an increased dose during pregnancy.

J Acquir Immune Defic Syndr 2008 Dec;49(5):485-91

Department of Pediatrics, Boston University School of Medicine, and Infectious Disease Division, Children's Hospital Boston, Boston, MA 02118, USA.

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http://pdfs.journals.lww.com/jaids/2008/12150/Lopinavir_Expo
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
Publisher Site
http://dx.doi.org/10.1097/QAI.0b013e318186edd0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912695PMC
December 2008

Nevirapine concentrations in newborns receiving an extended prophylactic regimen.

J Acquir Immune Defic Syndr 2008 Mar;47(3):334-7

Department of Pediatrics, Boston University School of Medicine, Boston, MA 02118, USA.

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March 2008

Population pharmacokinetics of lamivudine in human immunodeficiency virus-exposed and -infected infants.

Antimicrob Agents Chemother 2007 Dec 24;51(12):4297-302. Epub 2007 Sep 24.

Division of Pharmacology and Drug Discovery, Pediatric Pharmacology Research Unit, University of California San Diego, MC 8214, San Diego, CA 92103-8214, USA.

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http://dx.doi.org/10.1128/AAC.00332-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168008PMC
December 2007

Reduced lopinavir exposure during pregnancy.

AIDS 2006 Oct;20(15):1931-9

Department of Obstetrics and Gynecology, University of Southern California School of Medicine, Los Angeles, CA, USA.

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http://dx.doi.org/10.1097/01.aids.0000247114.43714.90DOI Listing
October 2006

Antiretroviral concentrations in breast-feeding infants of women in Botswana receiving antiretroviral treatment.

J Infect Dis 2005 Sep 27;192(5):720-7. Epub 2005 Jul 27.

Department of Immunology and Infectious Diseases, Harvard School of Public Health, and Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1086/432483DOI Listing
September 2005

Pharmacotherapy of perinatal HIV.

Semin Fetal Neonatal Med 2005 Apr 20;10(2):161-75. Epub 2005 Jan 20.

University of California, San Diego, Pediatric Pharmacology Research Unit, 4094 Fourth Street #201, San Diego, CA 92103, USA.

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http://dx.doi.org/10.1016/j.siny.2004.10.001DOI Listing
April 2005

Pharmacokinetics of antiretrovirals in pregnant women.

Clin Pharmacokinet 2004 ;43(15):1071-87

Boston University School of Medicine, Boston, Massachusetts 02118, USA.

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http://dx.doi.org/10.2165/00003088-200443150-00002DOI Listing
March 2005

Neonatal necrotizing enterocolitis with intestinal perforation in extremely premature infants receiving early indomethacin treatment for patent ductus arteriosus.

J Perinatol 2002 Oct-Nov;22(7):535-40

Department of Pediatrics, Boston University School of Medicine, Boston Medical Center, Boston, MA 02218, USA.

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http://dx.doi.org/10.1038/sj.jp.7210795DOI Listing
December 2002

Concentrations of protease inhibitors in cord blood after in utero exposure.

Pediatr Infect Dis J 2002 Sep;21(9):835-8

Boston University School of Medicine, and Statistical and Data Analysis Center/Harvard School of Public Health, Boston, MA, USA.

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http://dx.doi.org/10.1097/00006454-200209000-00010DOI Listing
September 2002