Mark McVey

Mark McVey

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Mark McVey

Mark McVey

Publications by authors named "Mark McVey"

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Transfusion-related Acute Lung Injury in the Perioperative Patient.

Anesthesiology 2019 Sep;131(3):693-715

From the Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Canada (M.J.M., J.W.S., W.M.K) Departments of Physiology and Anesthesia (M.J.M.) Pharmacology (J.W.S.) Laboratory Medicine-Pathobiology (C.C.-G.) Medicine-Division of Hematology (C.C.-G.) Anesthesia and Pain Management, University Health Network (K.K.) Physiology and Surgery (W.M.K.) University of Toronto, Toronto, Canada (C.C.-G.) Sickkids Department of Anesthesia and Pain Medicine (M.J.M.) Division of Hematology and Transfusion Medicine (R.K., J.W.S.), Lund University, Lund, Sweden Department of Experimental Immunohematology, Sanquin Research, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands (R.K.) Departments of Laboratory Hematology (Blood Transfusion Laboratory), Laboratory Medicine Program (C.C.-G.) Medical Oncology and Hematology (C.C.-G.) University Health Network, Toronto, Canada (K.K.) Department of Clinical Pathology, Blood and Tissue Bank, Sunnybrook Health Sciences Centre, Toronto, Canada (C.C.-G.) Institute of Physiology, Charité University Berlin, Berlin, Germany (W.M.K.).

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http://dx.doi.org/10.1097/ALN.0000000000002687DOI Listing
September 2019

A regional massive hemorrhage protocol developed through a modified Delphi technique.

CMAJ Open 2019 Jul-Sep;7(3):E546-E561. Epub 2019 Sep 3.

Departments of Laboratory Medicine and Molecular Diagnostics (Callum, Chin, Viveiros), Surgery (Nathens, Nascimento), Emergency Services (McDonald), Critical Care Medicine (Adhikari) and Anesthesia (Margarido), Sunnybrook Health Sciences Centre; Departments of Laboratory Medicine and Pathobiology (Callum, Pendergrast, Skeate, Pavenski), Anesthesia (McVey, Karkouti, Alam, Margarido), Surgery (Nathens, Nascimento, Rizoli) and Paediatrics (Beno), University of Toronto; Division of Emergency Medicine (Yeh, Petrosoniak, McDonald, MacDonald), Department of Medicine, University of Toronto; Departments of Emergency Medicine (Petrosoniak), Surgery (Rizoli) and Laboratory Medicine (Sholzberg, Pavenski), St. Michael's Hospital; Department of Anesthesia and Pain Medicine (McVey, Skelton), The Hospital for Sick Children; Ontario Regional Blood Coordinating Network (Cope, Thompson, Collins, Owens); Department of Anesthesia and Pain Management (Karkouti), Sinai Health System, University Health Network, and Women's College Hospital, Toronto, Ont.; Department of Anesthesiology and Pain Medicine (Murto), Children's Hospital of Eastern Ontario; Department of Anesthesiology and Pain Medicine (Murto), University of Ottawa, Ottawa, Ont.; Paediatric Emergency Medicine (Beno), The Hospital for Sick Children; Department of Clinical Pathology (Pendergrast), University Health Network, Toronto, Ont.; Ornge Transport Medicine (McDonald, MacDonald), Mississauga, Ont.; Interdepartmental Division of Critical Care Medicine (Adhikari), University of Toronto; Department of Anesthesia (Alam, Arnold), North York General Hospital, Toronto, Ont.; McMaster Centre for Transfusion Research (Arnold, Pai, Zeller); Departments of Medicine (Pai, Zeller) and Pathology and Molecular Medicine (Pai), McMaster University, Hamilton, Ont.; Canadian Blood Services (Arnold, Skeate, White); St. Michael's Hospital (Barratt, Chaudhry, Harvey), Toronto, Ont.; Department of Surgery (Beckett), McGill University, Montréal, Que.; Canadian Forces Health Services (Beckett), Ottawa, Ont.; Sunnybrook Health Sciences Centre (Brenneman), Toronto, Ont.; General Surgery, Acute Care and Trauma (Lampron), The Ottawa Hospital; Departments of Surgery (Lampron), Medicine (Tinmouth) and Laboratory Medicine and Pathology (Tinmouth), Faculty of Medicine, University of Ottawa, Ottawa, Ont.; Trauma Program and Quality Assurance (McFarlan), St. Michael's Hospital, Toronto, Ont.; Departments of Pathology (Ruijs) and Surgery (Van Heest), William Osler Health Centre, Brampton, Ont.; Lakeridge Health Corporation (Syer), Oshawa, Ont.; Department of Critical Care (Theriault), Health Sciences North, Sudbury, Ont.; Division of Hematology (Tinmouth), The Ottawa Hospital; University of Ottawa Centre for Transfusion Research (Tinmouth), Ottawa Hospital Research Institute, Ottawa, Ont.; Canadian Blood Services (Zeller), Ancaster, Ont.

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http://dx.doi.org/10.9778/cmajo.20190042DOI Listing
September 2019

A suspected case of anesthesia-induced rhabdomyolysis in a child undergoing strabismus surgery.

J AAPOS 2019 Jun 5;23(3):167-169. Epub 2019 Feb 5.

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jaapos.2019.01.006DOI Listing
June 2019

Extracellular vesicles in lung health, disease, and therapy.

Am J Physiol Lung Cell Mol Physiol 2019 Jun 20;316(6):L977-L989. Epub 2019 Mar 20.

Keenan Research Centre for Biomedical Science, St. Michael's Hospital , Toronto, Ontario , Canada.

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http://dx.doi.org/10.1152/ajplung.00546.2018DOI Listing
June 2019

The Regenerative Potential of Amniotic Fluid Stem Cell Extracellular Vesicles: Lessons Learned by Comparing Different Isolation Techniques.

Sci Rep 2019 Feb 12;9(1):1837. Epub 2019 Feb 12.

Developmental and Stem Cell Biology Program, Peter Gilgan Centre for Research and Learning, The Hospital for Sick Children, Toronto, M5G 0A4, Canada.

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http://dx.doi.org/10.1038/s41598-018-38320-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372651PMC
February 2019

Extracellular vesicles: biomarkers and regulators of vascular function during extracorporeal circulation.

Oncotarget 2018 Dec 14;9(98):37229-37251. Epub 2018 Dec 14.

Keenan Research Centre for Biomedical Science, St Michael's Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.18632/oncotarget.26433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324688PMC
December 2018

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.

Authors:
Clotilde Théry Kenneth W Witwer Elena Aikawa Maria Jose Alcaraz Johnathon D Anderson Ramaroson Andriantsitohaina Anna Antoniou Tanina Arab Fabienne Archer Georgia K Atkin-Smith D Craig Ayre Jean-Marie Bach Daniel Bachurski Hossein Baharvand Leonora Balaj Shawn Baldacchino Natalie N Bauer Amy A Baxter Mary Bebawy Carla Beckham Apolonija Bedina Zavec Abderrahim Benmoussa Anna C Berardi Paolo Bergese Ewa Bielska Cherie Blenkiron Sylwia Bobis-Wozowicz Eric Boilard Wilfrid Boireau Antonella Bongiovanni Francesc E Borràs Steffi Bosch Chantal M Boulanger Xandra Breakefield Andrew M Breglio Meadhbh Á Brennan David R Brigstock Alain Brisson Marike Ld Broekman Jacqueline F Bromberg Paulina Bryl-Górecka Shilpa Buch Amy H Buck Dylan Burger Sara Busatto Dominik Buschmann Benedetta Bussolati Edit I Buzás James Bryan Byrd Giovanni Camussi David Rf Carter Sarah Caruso Lawrence W Chamley Yu-Ting Chang Chihchen Chen Shuai Chen Lesley Cheng Andrew R Chin Aled Clayton Stefano P Clerici Alex Cocks Emanuele Cocucci Robert J Coffey Anabela Cordeiro-da-Silva Yvonne Couch Frank Aw Coumans Beth Coyle Rossella Crescitelli Miria Ferreira Criado Crislyn D'Souza-Schorey Saumya Das Amrita Datta Chaudhuri Paola de Candia Eliezer F De Santana Olivier De Wever Hernando A Del Portillo Tanguy Demaret Sarah Deville Andrew Devitt Bert Dhondt Dolores Di Vizio Lothar C Dieterich Vincenza Dolo Ana Paula Dominguez Rubio Massimo Dominici Mauricio R Dourado Tom Ap Driedonks Filipe V Duarte Heather M Duncan Ramon M Eichenberger Karin Ekström Samir El Andaloussi Celine Elie-Caille Uta Erdbrügger Juan M Falcón-Pérez Farah Fatima Jason E Fish Miguel Flores-Bellver András Försönits Annie Frelet-Barrand Fabia Fricke Gregor Fuhrmann Susanne Gabrielsson Ana Gámez-Valero Chris Gardiner Kathrin Gärtner Raphael Gaudin Yong Song Gho Bernd Giebel Caroline Gilbert Mario Gimona Ilaria Giusti Deborah Ci Goberdhan André Görgens Sharon M Gorski David W Greening Julia Christina Gross Alice Gualerzi Gopal N Gupta Dakota Gustafson Aase Handberg Reka A Haraszti Paul Harrison Hargita Hegyesi An Hendrix Andrew F Hill Fred H Hochberg Karl F Hoffmann Beth Holder Harry Holthofer Baharak Hosseinkhani Guoku Hu Yiyao Huang Veronica Huber Stuart Hunt Ahmed Gamal-Eldin Ibrahim Tsuneya Ikezu Jameel M Inal Mustafa Isin Alena Ivanova Hannah K Jackson Soren Jacobsen Steven M Jay Muthuvel Jayachandran Guido Jenster Lanzhou Jiang Suzanne M Johnson Jennifer C Jones Ambrose Jong Tijana Jovanovic-Talisman Stephanie Jung Raghu Kalluri Shin-Ichi Kano Sukhbir Kaur Yumi Kawamura Evan T Keller Delaram Khamari Elena Khomyakova Anastasia Khvorova Peter Kierulf Kwang Pyo Kim Thomas Kislinger Mikael Klingeborn David J Klinke Miroslaw Kornek Maja M Kosanović Árpád Ferenc Kovács Eva-Maria Krämer-Albers Susanne Krasemann Mirja Krause Igor V Kurochkin Gina D Kusuma Sören Kuypers Saara Laitinen Scott M Langevin Lucia R Languino Joanne Lannigan Cecilia Lässer Louise C Laurent Gregory Lavieu Elisa Lázaro-Ibáñez Soazig Le Lay Myung-Shin Lee Yi Xin Fiona Lee Debora S Lemos Metka Lenassi Aleksandra Leszczynska Isaac Ts Li Ke Liao Sten F Libregts Erzsebet Ligeti Rebecca Lim Sai Kiang Lim Aija Linē Karen Linnemannstöns Alicia Llorente Catherine A Lombard Magdalena J Lorenowicz Ákos M Lörincz Jan Lötvall Jason Lovett Michelle C Lowry Xavier Loyer Quan Lu Barbara Lukomska Taral R Lunavat Sybren Ln Maas Harmeet Malhi Antonio Marcilla Jacopo Mariani Javier Mariscal Elena S Martens-Uzunova Lorena Martin-Jaular M Carmen Martinez Vilma Regina Martins Mathilde Mathieu Suresh Mathivanan Marco Maugeri Lynda K McGinnis Mark J McVey David G Meckes Katie L Meehan Inge Mertens Valentina R Minciacchi Andreas Möller Malene Møller Jørgensen Aizea Morales-Kastresana Jess Morhayim François Mullier Maurizio Muraca Luca Musante Veronika Mussack Dillon C Muth Kathryn H Myburgh Tanbir Najrana Muhammad Nawaz Irina Nazarenko Peter Nejsum Christian Neri Tommaso Neri Rienk Nieuwland Leonardo Nimrichter John P Nolan Esther Nm Nolte-'t Hoen Nicole Noren Hooten Lorraine O'Driscoll Tina O'Grady Ana O'Loghlen Takahiro Ochiya Martin Olivier Alberto Ortiz Luis A Ortiz Xabier Osteikoetxea Ole Østergaard Matias Ostrowski Jaesung Park D Michiel Pegtel Hector Peinado Francesca Perut Michael W Pfaffl Donald G Phinney Bartijn Ch Pieters Ryan C Pink David S Pisetsky Elke Pogge von Strandmann Iva Polakovicova Ivan Kh Poon Bonita H Powell Ilaria Prada Lynn Pulliam Peter Quesenberry Annalisa Radeghieri Robert L Raffai Stefania Raimondo Janusz Rak Marcel I Ramirez Graça Raposo Morsi S Rayyan Neta Regev-Rudzki Franz L Ricklefs Paul D Robbins David D Roberts Silvia C Rodrigues Eva Rohde Sophie Rome Kasper Ma Rouschop Aurelia Rughetti Ashley E Russell Paula Saá Susmita Sahoo Edison Salas-Huenuleo Catherine Sánchez Julie A Saugstad Meike J Saul Raymond M Schiffelers Raphael Schneider Tine Hiorth Schøyen Aaron Scott Eriomina Shahaj Shivani Sharma Olga Shatnyeva Faezeh Shekari Ganesh Vilas Shelke Ashok K Shetty Kiyotaka Shiba Pia R-M Siljander Andreia M Silva Agata Skowronek Orman L Snyder Rodrigo Pedro Soares Barbara W Sódar Carolina Soekmadji Javier Sotillo Philip D Stahl Willem Stoorvogel Shannon L Stott Erwin F Strasser Simon Swift Hidetoshi Tahara Muneesh Tewari Kate Timms Swasti Tiwari Rochelle Tixeira Mercedes Tkach Wei Seong Toh Richard Tomasini Ana Claudia Torrecilhas Juan Pablo Tosar Vasilis Toxavidis Lorena Urbanelli Pieter Vader Bas Wm van Balkom Susanne G van der Grein Jan Van Deun Martijn Jc van Herwijnen Kendall Van Keuren-Jensen Guillaume van Niel Martin E van Royen Andre J van Wijnen M Helena Vasconcelos Ivan J Vechetti Tiago D Veit Laura J Vella Émilie Velot Frederik J Verweij Beate Vestad Jose L Viñas Tamás Visnovitz Krisztina V Vukman Jessica Wahlgren Dionysios C Watson Marca Hm Wauben Alissa Weaver Jason P Webber Viktoria Weber Ann M Wehman Daniel J Weiss Joshua A Welsh Sebastian Wendt Asa M Wheelock Zoltán Wiener Leonie Witte Joy Wolfram Angeliki Xagorari Patricia Xander Jing Xu Xiaomei Yan María Yáñez-Mó Hang Yin Yuana Yuana Valentina Zappulli Jana Zarubova Vytautas Žėkas Jian-Ye Zhang Zezhou Zhao Lei Zheng Alexander R Zheutlin Antje M Zickler Pascale Zimmermann Angela M Zivkovic Davide Zocco Ewa K Zuba-Surma

J Extracell Vesicles 2018 23;7(1):1535750. Epub 2018 Nov 23.

Jagiellonian University, Faculty of Biochemistry, Biophysics and Biotechnology, Department of Cell Biology, Kraków, Poland.

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https://www.tandfonline.com/doi/full/10.1080/20013078.2018.1
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http://dx.doi.org/10.1080/20013078.2018.1535750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322352PMC
November 2018

The Pathogenesis of Choanal Atresia.

JAMA Otolaryngol Head Neck Surg 2018 08;144(8):758-759

Department of Otolaryngology-Head and Neck Surgery, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1001/jamaoto.2018.1246DOI Listing
August 2018

Targeting Transfusion-Related Acute Lung Injury: The Journey From Basic Science to Novel Therapies.

Crit Care Med 2018 05;46(5):e452-e458

Division of Hematology and Transfusion Medicine, Lund University, Lund, Sweden.

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http://Insights.ovid.com/crossref?an=00003246-201805000-0004
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http://dx.doi.org/10.1097/CCM.0000000000002989DOI Listing
May 2018

Intravenous immunoglobulin treatment of spleen cells from patients with immune thrombocytopenia significantly increases the percentage of myeloid-derived suppressor cells.

Br J Haematol 2018 04 6;181(2):262-264. Epub 2017 Feb 6.

Keenan Research Centre for Biomedical Science of St. Michaels Hospital, Rochester, NY, USA.

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http://dx.doi.org/10.1111/bjh.14542DOI Listing
April 2018

Improved resolution in extracellular vesicle populations using 405 instead of 488 nm side scatter.

J Extracell Vesicles 2018 22;7(1):1454776. Epub 2018 Mar 22.

Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Canada.

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http://dx.doi.org/10.1080/20013078.2018.1454776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5912191PMC
March 2018

Mature murine megakaryocytes present antigen-MHC class I molecules to T cells and transfer them to platelets.

Blood Adv 2017 Sep 8;1(20):1773-1785. Epub 2017 Sep 8.

Toronto Platelet Immunobiology Group, Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.1182/bloodadvances.2017007021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728336PMC
September 2017

Anesthesia for Complex Cardiovascular Surgery in a Patient With PHACES Syndrome and Review of the Literature.

J Cardiothorac Vasc Anesth 2017 06 11;31(3):1042-1047. Epub 2016 Jul 11.

Department of Anesthesia, University of Toronto, Toronto, ON, Canada; Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, ON, Canada.

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http://dx.doi.org/10.1053/j.jvca.2016.07.010DOI Listing
June 2017

Acid sphingomyelinase mediates murine acute lung injury following transfusion of aged platelets.

Am J Physiol Lung Cell Mol Physiol 2017 05 10;312(5):L625-L637. Epub 2017 Mar 10.

Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Ontario, Canada;

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http://dx.doi.org/10.1152/ajplung.00317.2016DOI Listing
May 2017

Microparticles as biomarkers of lung disease: enumeration in biological fluids using lipid bilayer microspheres.

Am J Physiol Lung Cell Mol Physiol 2016 05 4;310(9):L802-14. Epub 2016 Mar 4.

Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Ontario, Canada; Departments of Physiology, Surgery, University of Toronto, Toronto, Ontario, Canada; Institute of Physiology, Charité-Universitätsmedizin Berlin, Germany; and German Heart Institute, Berlin, Germany.

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http://dx.doi.org/10.1152/ajplung.00369.2015DOI Listing
May 2016

Microparticles as biomarkers of lung disease: enumeration in biological fluids using lipid bilayer microspheres.

Am J Physiol Lung Cell Mol Physiol 2016 05 4;310(9):L802-14. Epub 2016 Mar 4.

Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Ontario, Canada; Departments of Physiology, Surgery, University of Toronto, Toronto, Ontario, Canada; Institute of Physiology, Charité-Universitätsmedizin Berlin, Germany; and German Heart Institute, Berlin, Germany.

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http://dx.doi.org/10.1152/ajplung.00369.2015DOI Listing
May 2016

IL-7 receptor recovery on CD8 T-cells isolated from HIV+ patients is inhibited by the HIV Tat protein.

PLoS One 2014 17;9(7):e102677. Epub 2014 Jul 17.

Ottawa Hospital Research Institute, Chronic Disease, Ottawa, Ontario, Canada; Division of Infectious Diseases, Ottawa Hospital General Campus, Ottawa, Ontario, Canada; Faculty of Medicine, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0102677PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4102547PMC
December 2015

Microparticles and acute lung injury.

Am J Physiol Lung Cell Mol Physiol 2012 Sep 22;303(5):L364-81. Epub 2012 Jun 22.

The Keenan Research Centre, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1152/ajplung.00354.2011DOI Listing
September 2012

When infections collide--gummatous syphilis in an HIV-infected individual.

Int J Infect Dis 2010 Sep 24;14 Suppl 3:e283-6. Epub 2010 Mar 24.

Faculty of Medicine, University of Toronto, 1 King's College Circle, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.ijid.2009.11.033DOI Listing
September 2010

An investigation of the effects of methylmercury in rats fed different dietary fats and proteins: testicular steroidogenic enzymes and serum testosterone levels.

Food Chem Toxicol 2008 Jan 14;46(1):270-9. Epub 2007 Aug 14.

Toxicology Research Division, Health Products and Foods Branch, Food Directorate, Health Canada, Sir Fredrick G. Banting Research Centre, 2202D1 Tunney's Pasture, Ottawa, ON, Canada K1A 0L2.

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http://dx.doi.org/10.1016/j.fct.2007.08.004DOI Listing
January 2008

Effects of dietary fats and proteins on rat testicular steroidogenic enzymes and serum testosterone levels.

Food Chem Toxicol 2008 Jan 11;46(1):259-69. Epub 2007 Sep 11.

Toxicology Research Division, Health Products and Foods Branch, Food Directorate, Health Canada, Sir Fredrick G. Banting Research Centre, 2202D1 Tunney's Pasture, Ottawa, ON, Canada K1A 0L2.

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http://linkinghub.elsevier.com/retrieve/pii/S027869150700341
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http://dx.doi.org/10.1016/j.fct.2007.08.045DOI Listing
January 2008

Interleukin-7 receptor expression on CD8 T-cells is downregulated by the HIV Tat protein.

J Acquir Immune Defic Syndr 2006 Nov;43(3):257-69

Ottawa Health Research Institute, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1097/01.qai.0000230319.78288.f4DOI Listing
November 2006

Altered testicular microsomal steroidogenic enzyme activities in rats with lifetime exposure to soy isoflavones.

J Steroid Biochem Mol Biol 2004 Dec 21;92(5):435-46. Epub 2004 Dec 21.

Department of Cellular and Molecular Medicine and Obstetrics and Gynecology, Reproductive Biology Unit, University of Ottawa, Ont., Canada.

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http://dx.doi.org/10.1016/j.jsbmb.2004.08.002DOI Listing
December 2004

Increased serum and testicular androgen levels in F1 rats with lifetime exposure to soy isoflavones.

Reprod Toxicol 2004 Jul;18(5):677-85

Reproductive Biology Unit, Departments of Cellular and Molecular Medicine and Obstetrics and Gynecology, University of Ottawa, Ottawa, ON, Canada.

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http://dx.doi.org/10.1016/j.reprotox.2004.04.005DOI Listing
July 2004

Inhibition of rat testis microsomal 3beta-hydroxysteroid dehydrogenase activity by tributyltin.

J Steroid Biochem Mol Biol 2003 Jul;86(1):99-105

Toxicology Research Division, Health Products and Foods Branch, Food Directorate, Health Canada, Reproductive Biology Unit, Department of Cellular and Molecular Medicine, University of Ottawa, Ont., K1A 0L2, Ottawa, Canada.

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http://dx.doi.org/10.1016/s0960-0760(03)00256-5DOI Listing
July 2003