Publications by authors named "Mark Marsh"

64Publications

Two-pore channels as master regulators of membrane trafficking and endocytic well-being.

Curr Opin Physiol 2020 Oct 14;17:163-168. Epub 2020 Aug 14.

Department of Cell and Developmental Biology, University College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cophys.2020.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7426208PMC
October 2020

Rapid formation of human immunodeficiency virus-like particles.

Proc Natl Acad Sci U S A 2020 09 17;117(35):21637-21646. Epub 2020 Aug 17.

Department of Medicine, Imperial College London, W12 0NN London, United Kingdom;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.2008156117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474690PMC
September 2020

The Nef Protein of the Macrophage Tropic HIV-1 Strain AD8 Counteracts Human BST-2/Tetherin.

Viruses 2020 04 18;12(4). Epub 2020 Apr 18.

MRC Laboratory for Molecular Cell Biology, University College London, WC1E 6BT London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/v12040459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232323PMC
April 2020

Super-beacons: Open-source probes with spontaneous tuneable blinking compatible with live-cell super-resolution microscopy.

Traffic 2020 05 30;21(5):375-385. Epub 2020 Mar 30.

MRC-Laboratory for Molecular Cell Biology, University College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/tra.12728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643006PMC
May 2020

A biophysical perspective on receptor-mediated virus entry with a focus on HIV.

Biochim Biophys Acta Biomembr 2020 06 19;1862(6):183158. Epub 2019 Dec 19.

Medical Research Council Laboratory for Molecular Cell Biology, University College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbamem.2019.183158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156917PMC
June 2020

Twenty years of Traffic.

Traffic 2020 01;21(1):4-5

Department of Biology, 203 Biology, Johns Hopkins University, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/tra.12688DOI Listing
January 2020

Targeting viral entry as a strategy for broad-spectrum antivirals.

F1000Res 2019 12;8. Epub 2019 Sep 12.

MRC Laboratory for Molecular Cell Biology, University College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12688/f1000research.19694.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743247PMC
June 2020

KHNYN is essential for the zinc finger antiviral protein (ZAP) to restrict HIV-1 containing clustered CpG dinucleotides.

Elife 2019 07 9;8. Epub 2019 Jul 9.

Department of Infectious Diseases, School of Immunology and Microbial Sciences, King's College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7554/eLife.46767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615859PMC
July 2019

Alphavirus-induced hyperactivation of PI3K/AKT directs pro-viral metabolic changes.

PLoS Pathog 2018 01 29;14(1):e1006835. Epub 2018 Jan 29.

Department of Microbiology, Tumor and Cell Biology (MTC), Karolinska Institutet, Stockholm, SE, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1006835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805360PMC
January 2018

The intracellular plasma membrane-connected compartment in the assembly of HIV-1 in human macrophages.

BMC Biol 2016 06 23;14:50. Epub 2016 Jun 23.

MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London, WC1E 6BT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12915-016-0272-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919869PMC
June 2016

Alphavirus Restriction by IFITM Proteins.

Traffic 2016 09 24;17(9):997-1013. Epub 2016 Jun 24.

MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London, WC1E 6BT, UK.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025721PMC
http://dx.doi.org/10.1111/tra.12416DOI Listing
September 2016

RETROSPECTIVE. Alan Hall (1952-2015).

Science 2015 Nov;350(6264):1039

MRC-Laboratory for Molecular Cell Biology, University College London, Gower Street, London WC1E 6BT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aad8407DOI Listing
November 2015

Signal peptide-binding drug as a selective inhibitor of co-translational protein translocation.

PLoS Biol 2014 Dec 2;12(12):e1002011. Epub 2014 Dec 2.

MRC-Laboratory for Molecular Cell Biology, University College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pbio.1002011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251836PMC
December 2014

Flat clathrin lattices: stable features of the plasma membrane.

Mol Biol Cell 2014 Nov 27;25(22):3581-94. Epub 2014 Aug 27.

MRC Laboratory for Molecular Cell Biology, London WC1E 6BT, United Kingdom

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1091/mbc.E14-06-1154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230618PMC
November 2014

A membrane topology model for human interferon inducible transmembrane protein 1.

PLoS One 2014 8;9(8):e104341. Epub 2014 Aug 8.

MRC Laboratory for Molecular Cell Biology, University College London, London, United Kingdom; MRC Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0104341PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126714PMC
April 2015

Tetherin can restrict cell-free and cell-cell transmission of HIV from primary macrophages to T cells.

PLoS Pathog 2014 Jul 3;10(7):e1004189. Epub 2014 Jul 3.

MRC/UCL Laboratory for Molecular Cell Biology, University College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1004189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081785PMC
July 2014

Editorial overview - virus entry: towards reality - refining models of virus entry.

Curr Opin Virol 2014 Feb 31;4:v-vi. Epub 2014 Jan 31.

Institute for Biomedical Research, Centre for Human Virology, University of Birmingham, Birmingham B15 2TT, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.coviro.2014.01.001DOI Listing
February 2014

Tetherin restricts herpes simplex virus 1 and is antagonized by glycoprotein M.

J Virol 2013 Dec 25;87(24):13124-33. Epub 2013 Sep 25.

University College London, Medical Research Council Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JVI.02250-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3838283PMC
December 2013

Organization and regulation of intracellular plasma membrane-connected HIV-1 assembly compartments in macrophages.

BMC Biol 2013 Aug 2;11:89. Epub 2013 Aug 2.

Medical Research Council Laboratory for Molecular Cell Biology, University College London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1741-7007-11-89DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751737PMC
August 2013

Characterization of tetraspanins CD9, CD53, CD63, and CD81 in monocytes and macrophages in HIV-1 infection.

J Leukoc Biol 2013 Jun 9;93(6):913-20. Epub 2013 Apr 9.

Centre for Virology, The Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.0812391DOI Listing
June 2013

Regulation of endocytic clathrin dynamics by cargo ubiquitination.

Dev Cell 2012 Sep 30;23(3):519-32. Epub 2012 Aug 30.

Program in Cell Biology, Department of Psychiatry, University of California, San Francisco, San Francisco, CA 94158, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.devcel.2012.08.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470869PMC
September 2012

The cell biology of receptor-mediated virus entry.

J Cell Biol 2011 Dec 28;195(7):1071-82. Epub 2011 Nov 28.

Cell Biology Unit, Medical Research Council Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, England, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1083/jcb.201108131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246895PMC
December 2011

β2 integrin adhesion complexes maintain the integrity of HIV-1 assembly compartments in primary macrophages.

Traffic 2012 Feb 28;13(2):273-91. Epub 2011 Nov 28.

Cell Biology Unit, Medical Research Council Laboratory for Molecular Cell Biology, University College London, London, WC1E 6BT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1600-0854.2011.01306.xDOI Listing
February 2012

The ESCRT-0 component HRS is required for HIV-1 Vpu-mediated BST-2/tetherin down-regulation.

PLoS Pathog 2011 Feb 3;7(2):e1001265. Epub 2011 Feb 3.

Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1001265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033365PMC
February 2011

The role of ubiquitination in lysosomal trafficking of δ-opioid receptors.

Traffic 2011 Feb 22;12(2):170-84. Epub 2010 Dec 22.

Program in Cell Biology, Department of Biochemistry and Biophysics, University of California, San Francisco, CA, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/j.1600-0854.2010.01145.x
Publisher Site
http://dx.doi.org/10.1111/j.1600-0854.2010.01145.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3075729PMC
February 2011

Inositol pyrophosphate mediated pyrophosphorylation of AP3B1 regulates HIV-1 Gag release.

Proc Natl Acad Sci U S A 2009 Dec 23;106(50):21161-6. Epub 2009 Nov 23.

Cell Biology Unit, Medical Research Council Laboratory for Molecular Cell Biology, and Department of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0909176106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795533PMC
December 2009

Simian immunodeficiency virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by intracellular sequestration.

Proc Natl Acad Sci U S A 2009 Dec 28;106(49):20889-94. Epub 2009 Oct 28.

Medical Research Council Centre for Medical Molecular Virology, Division of Infection and Immunity, University College London, 46 Cleveland Street, London W1T 4JF, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0907075106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791628PMC
December 2009

Analysis of chemokine receptor endocytosis and intracellular trafficking.

Methods Enzymol 2009 ;460:357-77

Cell Biology Unit, MRC Laboratory for Molecular Cell Biology, and Department of Cell and Developmental Biology, University College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0076-6879(09)05218-5DOI Listing
August 2009

HIV assembly and budding in macrophages.

Biochem Soc Trans 2009 Feb;37(Pt 1):185-9

Cell Biology Unit, MRC Laboratory for Molecular Cell Biology and Department of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/BST0370185DOI Listing
February 2009

CD63 is not required for production of infectious human immunodeficiency virus type 1 in human macrophages.

J Virol 2008 May 5;82(10):4751-61. Epub 2008 Mar 5.

MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JVI.02320-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2346747PMC
May 2008

Cell biology. No ESCRTs for exosomes.

Science 2008 Feb;319(5867):1191-2

Cell Biology Unit, MRC Laboratory for Molecular Cell Biology and Department of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1155750DOI Listing
February 2008

ALIX catches HIV.

Cell Host Microbe 2007 Mar;1(1):5-7

Department of Infectious Diseases, King's College London School of Medicine, Second Floor, New Guy's House, Guy's Hospital, London SE1 9RT, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chom.2007.02.006DOI Listing
March 2007

The ESCRT machinery is not required for human cytomegalovirus envelopment.

Cell Microbiol 2007 Dec 29;9(12):2955-67. Epub 2007 Aug 29.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, Campus Universidad Autonoma, Madrid 28049, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1462-5822.2007.01024.xDOI Listing
December 2007

In macrophages, HIV-1 assembles into an intracellular plasma membrane domain containing the tetraspanins CD81, CD9, and CD53.

J Cell Biol 2007 Apr 16;177(2):329-41. Epub 2007 Apr 16.

Cell Biology Unit, Medical Research Council Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, England, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1083/jcb.200609050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2064140PMC
April 2007

Electron microscopy analysis of viral morphogenesis.

Methods Cell Biol 2007 ;79:515-42

Cell Biology Unit, MRC Laboratory for Molecular Cell Biology and Department of Biochemistry and Molecular Biology, University College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0091-679X(06)79020-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103132PMC
April 2007

Bluetongue virus entry into cells.

J Virol 2007 May 31;81(9):4819-27. Epub 2007 Jan 31.

Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1 7HT, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JVI.02284-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1900141PMC
May 2007

A conserved dileucine motif mediates clathrin and AP-2-dependent endocytosis of the HIV-1 envelope protein.

Mol Biol Cell 2007 Feb 15;18(2):414-25. Epub 2006 Nov 15.

Cell Biology Unit, MRC-Laboratory for Molecular Cell Biology and Department of Biochemistry and Molecular Biology, University College London, London WC1E 6BT, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1091/mbc.e06-06-0535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1783771PMC
February 2007

Virus entry: open sesame.

Cell 2006 Feb;124(4):729-40

Cell Biology Unit, MRC Laboratory for Molecular Cell Biology, and Department of Biochemistry and Molecular Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2006.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112260PMC
February 2006

HIV interaction with endosomes in macrophages and dendritic cells.

Blood Cells Mol Dis 2005 Sep-Oct;35(2):136-42

Cell Biology Unit, MRC-Laboratory for Molecular Cell Biology, and Department of Biochemistry and Molecular Biology, University College London, Gower Street, London WC1E 6BT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bcmd.2005.06.006DOI Listing
January 2006

Agonist-induced endocytosis of CC chemokine receptor 5 is clathrin dependent.

Mol Biol Cell 2005 Feb 9;16(2):902-17. Epub 2004 Dec 9.

Cell Biology Unit, Medical Research Council Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1091/mbc.e04-08-0687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC545921PMC
February 2005

Multiphoton-FLIM quantification of the EGFP-mRFP1 FRET pair for localization of membrane receptor-kinase interactions.

Biophys J 2005 Feb 5;88(2):1224-37. Epub 2004 Nov 5.

Randall Division of Cell and Molecular Biophysics, Guy's Campus, King's College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1529/biophysj.104.050153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1305125PMC
February 2005

Endosomes, exosomes and Trojan viruses.

Trends Microbiol 2004 Jul;12(7):310-6

Cell Biology Unit, MRC Laboratory for Molecular Cell Biology and Department of Biochemistry and Molecular Biology, University College London, Gower Street, London WC1E 6BT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tim.2004.05.004DOI Listing
July 2004

pH-independent endocytic cycling of the chemokine receptor CCR5.

Traffic 2004 Jul;5(7):529-43

Cell Biology Unit, Medical Research Council Laboratory for Molecular Cell Biology, University College London, Gower Street, London WC1E 6BT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1600-0854.2004.00200.xDOI Listing
July 2004

HIV's great escape.

Nat Med 2003 Oct;9(10):1262-3

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm1003-1262DOI Listing
October 2003

Infectious HIV-1 assembles in late endosomes in primary macrophages.

J Cell Biol 2003 Aug 28;162(3):443-55. Epub 2003 Jul 28.

Cell Biology Unit, Medical Research (MRC) Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1083/jcb.200304008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172706PMC
August 2003

Endocytosis of the viral chemokine receptor US28 does not require beta-arrestins but is dependent on the clathrin-mediated pathway.

Traffic 2003 Apr;4(4):243-53

Cell Biology Unit, MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1034/j.1600-0854.2003.00079.xDOI Listing
April 2003

The on-off story of protein palmitoylation.

Trends Cell Biol 2003 Jan;13(1):32-42

Peter Gorer Department of Immunobiology, Kings College London, 3rd Floor New Guy's House, Guy's Hospital, London SE1 9RT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0962-8924(02)00008-9DOI Listing
January 2003

NK1 receptor fused to beta-arrestin displays a single-component, high-affinity molecular phenotype.

Mol Pharmacol 2002 Jul;62(1):30-7

Laboratory for Molecular Pharmacology, Department of Pharmacology, The Panum Institute, University of Copenhagen, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/mol.62.1.30DOI Listing
July 2002

Localization of HCMV UL33 and US27 in endocytic compartments and viral membranes.

Traffic 2002 Mar;3(3):218-32

Department of Biochemistry and Molecular Biology, Cell Biology Unit, MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London WC1E 6BT, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1034/j.1600-0854.2002.030307.xDOI Listing
March 2002