Publications by authors named "Mark Lindsay"

99Publications

The genetics of aortopathies: Hereditary thoracic aortic aneurysms and dissections.

Am J Med Genet C Semin Med Genet 2020 03 8;184(1):136-148. Epub 2020 Feb 8.

Thoracic Aortic Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/ajmg.c.31771DOI Listing
March 2020

Idiopathic Pulmonary Fibrosis: Pathogenesis and the Emerging Role of Long Non-Coding RNAs.

Int J Mol Sci 2020 Jan 14;21(2). Epub 2020 Jan 14.

Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath, BA2 7AY, UK.

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http://dx.doi.org/10.3390/ijms21020524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013390PMC
January 2020

Catalytic Production of Glucose-Galactose Syrup from Greek Yogurt Acid Whey in a Continuous-Flow Reactor.

ChemSusChem 2020 Feb 21;13(4):791-802. Epub 2020 Jan 21.

Department of Chemical and Biological Engineering, University of Wisconsin-Madison, 1415 Engineering Drive, Madison, WI, 53706, USA.

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http://dx.doi.org/10.1002/cssc.201902847DOI Listing
February 2020

Gain-of-function pathogenic variants in SMAD4 are associated with neoplasia in Myhre syndrome.

Am J Med Genet A 2020 02 14;182(2):328-337. Epub 2019 Dec 14.

Division of Reproductive and Medical Genetics, Department of Obstetrics & Gynecology and Women's Health, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York.

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http://dx.doi.org/10.1002/ajmg.a.61430DOI Listing
February 2020

Ketamine Increases Proliferation of Human iPSC-Derived Neuronal Progenitor Cells via Insulin-Like Growth Factor 2 and Independent of the NMDA Receptor.

Cells 2019 09 24;8(10). Epub 2019 Sep 24.

Bio-Pharmaceutical Chemistry and Molecular Pharmacology, Faculty of Applied Natural Sciences, Technische Hochschule Köln, 51373 Leverkusen, Germany.

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http://dx.doi.org/10.3390/cells8101139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6830315PMC
September 2019

Case 28-2019: A 22-Year-Old Woman with Dyspnea and Chest Pain.

N Engl J Med 2019 09;381(11):1059-1067

From the Department of Pediatrics, UMass Memorial Medical Center, and the Department of Pediatrics, University of Massachusetts Medical School, Worcester (T.M.K.), the Departments of Pediatrics (M.E.L., T.B.K.), Radiology (B.P.L.), and Pathology (M.M.-K.), Massachusetts General Hospital, and the Departments of Pediatrics (M.E.L., T.B.K.), Radiology (B.P.L.), and Pathology (M.M.-K.), Harvard Medical School, Boston, and the Laboratory for Molecular Medicine, Partners HealthCare Personalized Medicine, Cambridge (M.H.H.) - all in Massachusetts.

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http://dx.doi.org/10.1056/NEJMcpc1904041DOI Listing
September 2019

MiR-574-5p: A Circulating Marker of Thoracic Aortic Aneurysm.

Int J Mol Sci 2019 08 12;20(16). Epub 2019 Aug 12.

Cardiovascular Research Unit, Luxembourg Institute of Health, 1A-B rue Edison, L-1445 Strassen, Luxembourg.

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http://dx.doi.org/10.3390/ijms20163924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6720007PMC
August 2019

Spontaneous coronary artery dissection and its association with takotsubo syndrome: Novel insights from a tertiary center registry.

Catheter Cardiovasc Interv 2020 02 29;95(3):485-491. Epub 2019 Apr 29.

Division of Cardiology, Massachusetts General Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1002/ccd.28314DOI Listing
February 2020

Long Non-Coding RNAs and the Innate Immune Response.

Noncoding RNA 2019 Apr 19;5(2). Epub 2019 Apr 19.

Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath, BA2 7AY, UK.

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https://www.mdpi.com/2311-553X/5/2/34
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http://dx.doi.org/10.3390/ncrna5020034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630897PMC
April 2019

Risk Factors, Imaging Findings, and Sex Differences in Spontaneous Coronary Artery Dissection.

Am J Cardiol 2019 06 8;123(11):1783-1787. Epub 2019 Mar 8.

Division of Cardiology, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2019.02.040DOI Listing
June 2019

Atmospheric sulfur is recycled to the crystalline continental crust during supercontinent formation.

Nat Commun 2018 10 22;9(1):4380. Epub 2018 Oct 22.

Department of Earth and Planetary Sciences and GEOTOP, McGill University, 3450 University Street, Montreal, QC, H3A 0E8, Canada.

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http://www.nature.com/articles/s41467-018-06691-3
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http://dx.doi.org/10.1038/s41467-018-06691-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197212PMC
October 2018

Epigenetics in Ascending Thoracic Aortic Aneurysm and Dissection.

Aorta (Stamford) 2018 Feb 27;6(1):1-12. Epub 2018 Jul 27.

Cardiovascular Research Unit, Luxembourg Institute of Health, Luxembourg, Luxembourg.

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http://dx.doi.org/10.1055/s-0038-1639610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136679PMC
February 2018

Medical management of aortic disease in children with Marfan syndrome.

Authors:
Mark E Lindsay

Curr Opin Pediatr 2018 10;30(5):639-644

Massachusetts General Hospital Thoracic Aortic Center.

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http://dx.doi.org/10.1097/MOP.0000000000000671DOI Listing
October 2018

Microsurgical Anatomy of the Vertical Rami of the Superior Longitudinal Fasciculus: An Intraparietal Sulcus Dissection Study.

Oper Neurosurg (Hagerstown) 2019 02;16(2):226-238

Aurora Neuroscience Innovation Insti-tute, Aurora St. Luke's Medical Center, Milwaukee, Wisconsin.

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http://dx.doi.org/10.1093/ons/opy077DOI Listing
February 2019

Endogenous Heparin Interferes with Quantification of MicroRNAs by RT-qPCR.

Clin Chem 2018 05 26;64(5):863-865. Epub 2018 Feb 26.

Cardiovascular Research Unit Luxembourg Institute of Health Strassen, Luxembourg

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http://dx.doi.org/10.1373/clinchem.2017.284653DOI Listing
May 2018

Case 39-2017. A 41-Year-Old Woman with Recurrent Chest Pain.

N Engl J Med 2017 12;377(25):2475-2484

From the Departments of Cardiology (S.V.T., L.M.S., M.E.L., M.J.W.) and Radiology (B.B.G.), Massachusetts General Hospital, and the Departments of Cardiology (S.V.T., L.M.S., M.E.L., M.J.W.) and Radiology (B.B.G.), Harvard Medical School - both in Boston.

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http://www.nejm.org/doi/10.1056/NEJMcpc1707558
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http://dx.doi.org/10.1056/NEJMcpc1707558DOI Listing
December 2017

Novel Mutation in (Filamin C) Causes Familial Restrictive Cardiomyopathy.

Circ Cardiovasc Genet 2017 Dec;10(6)

From the Cardiovascular Research Center, Massachusetts General Hospital, Charlestown (N.R.T., M.A.M., D.H., J.Y., V.A.P., R.W.M., S.C., E.D., D.J.M., M.L., S.A.L., I.J.D., P.T.E.); Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA (N.R.T., J.Y., V.A.P., S.A.L., H.L., P.T.E.); Department of Medicine I, Klinikum Grosshadern, University of Munich (LMU), Germany (S.C.); German Centre for Cardiovascular Research, Partner site Munich, Germany (S.C.); Division of Cardiology (M.A.S., D.J.M., N.S.S., M.L., S.A.L., I.J.D., P.T.E.) and Department of Pathology, Center for Systems Biology (J.R.S.), Massachusetts General Hospital, Boston; and Computational Biomedicine Section, Department of Medicine, Boston University School of Medicine, MA (H.L.).

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https://www.ahajournals.org/doi/10.1161/CIRCGENETICS.117.001
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http://dx.doi.org/10.1161/CIRCGENETICS.117.001780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802346PMC
December 2017

Cardiovascular Safety of Antidiabetic Drugs in the Hospital Setting.

Curr Diab Rep 2017 08;17(8):64

Department of Medicine, Division of Endocrinology, Metabolism, and Diabetes, University of Colorado Anschutz Medical Campus, MS8106, RC-1 South, Room 7103, 12801 East 17th Avenue, Aurora, CO, 80045, USA.

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http://dx.doi.org/10.1007/s11892-017-0884-1DOI Listing
August 2017

Cervical artery dissection expands the cardiovascular phenotype in FBN1-related Weill-Marchesani syndrome.

Am J Med Genet A 2017 Sep 11;173(9):2551-2556. Epub 2017 Jul 11.

Cardiovascular Genetics Program, Massachusetts General Hospital, Boston, Massachusetts.

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http://doi.wiley.com/10.1002/ajmg.a.38353
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http://dx.doi.org/10.1002/ajmg.a.38353DOI Listing
September 2017

Cerebrovascular fibromuscular dysplasia: The MGH cohort and literature review.

Neurol Clin Pract 2017 Jun;7(3):225-236

Department of Neurology (AMH, EZ, ABS, GAR), The Fireman Vascular Center (MRJ), and Thoracic Aortic Center and Cardiovascular Research Center (MEL), Massachusetts General Hospital; John R. Graham Headache Center (AMH), Brigham and Women's Faulkner Hospital, Boston; and Department of Neurology (EZ), Vanderbilt University Medical Center, Nashville, TN.

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http://dx.doi.org/10.1212/CPJ.0000000000000339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490381PMC
June 2017

Whole Transcriptome Analysis of Pre-invasive and Invasive Early Squamous Lung Carcinoma in Archival Laser Microdissected Samples.

Respir Res 2017 01 10;18(1):12. Epub 2017 Jan 10.

Manchester Thoracic Oncology Centre, University Hospital of South Manchester, Manchester, England, M23 9LT, UK.

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http://dx.doi.org/10.1186/s12931-016-0496-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223343PMC
January 2017

Highly sensitive dual mode electrochemical platform for microRNA detection.

Sci Rep 2016 11 8;6:36719. Epub 2016 Nov 8.

Department of Electronic &Electrical Engineering, University of Bath, Bath BA2 7AY, United Kingdom.

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http://dx.doi.org/10.1038/srep36719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099858PMC
November 2016

Clinical potential of oligonucleotide-based therapeutics in the respiratory system.

Pharmacol Ther 2017 01 19;169:83-103. Epub 2016 Oct 19.

Department of Pharmacy and Pharmacology, Claverton Down, University of Bath, Bath BA2 7AY, United Kingdom.

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http://dx.doi.org/10.1016/j.pharmthera.2016.10.009DOI Listing
January 2017

Characterization of TLR-induced inflammatory responses in COPD and control lung tissue explants.

Int J Chron Obstruct Pulmon Dis 2016 29;11:2409-2417. Epub 2016 Sep 29.

Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester and University Hospital of South Manchester, NHS Foundation Trust.

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http://dx.doi.org/10.2147/COPD.S105156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047739PMC
August 2017

Knockdown of Nuclear-Located Enhancer RNAs and Long ncRNAs Using Locked Nucleic Acid GapmeRs.

Methods Mol Biol 2017 ;1468:11-8

Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath, BA2 7AY, UK.

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http://dx.doi.org/10.1007/978-1-4939-4035-6_2DOI Listing
January 2018

Risk of Aortic Dissection in the Moderately Dilated Ascending Aorta.

J Am Coll Cardiol 2016 09;68(11):1209-1219

Division of Cardiac Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Thoracic Aortic Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2016.06.025DOI Listing
September 2016

Recurrent Aortic Dissection: Observations From the International Registry of Aortic Dissection.

Circulation 2016 Oct 1;134(14):1013-1024. Epub 2016 Sep 1.

From Thoracic Aortic Center (E.M.I., M.A., M.E.L.), Cardiology Division, Department of Medicine (E.M.I., M.E.L.), Cardiovascular Research Center (M.A., M.E.L.), and Pediatric Cardiology Division, Department of Pediatrics (M.E.L.), Massachusetts General Hospital and Harvard Medical School, Boston, MA; Brigham and Women's Hospital, Cardiology Division, Boston, MA (M.P.B.); Cardiac Surgery Department, University Hospital S. Orsola, Bologna, Italy (M.D.E.); Cardiovascular Center (J.F., D.M., K.E.) and Cardiac Surgery (H.P.), University of Michigan, Ann Arbor; Cardiology Division, University of Salerno, Salerno, Italy (E.B.); Department of Cardiology, Robert Bosch Hospital, Stuttgart, Germany (U.S.); Departments of Medicine and Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia (R.P.); Division of Cardiothoracic Surgery, Cedars-Sinai Med Center, Los Angeles, CA (A.K.); Department of Vascular and Endovascular Surgery, Klinikum rechts der Isar, Technical University Munich, Munich, Germany (H.-H.E.); Hopital Bichat, Université Paris, Paris, France (G.J.); Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital, Sydney, Australia (F.R.); and Royal Brompton & Harefield NHS Trust, Cardiology and Aortic Centre, London, UK (C.A.N.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.019359DOI Listing
October 2016

Transcriptional profiling identifies the long noncoding RNA plasmacytoma variant translocation (PVT1) as a novel regulator of the asthmatic phenotype in human airway smooth muscle.

J Allergy Clin Immunol 2017 Mar 2;139(3):780-789. Epub 2016 Jul 2.

Dubowitz Neuromuscular Centre, Molecular Neurosciences Section, Developmental Neurosciences Programme, UCL Institute of Child Health, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338875PMC
March 2017

Spectrum and Energy Levels of Five-Times Ionized Zirconium (Zr VI).

Phys Scr 2016 Feb 5;91(2). Epub 2016 Jan 5.

National Institute of Standards and Technology, Gaithersburg, MD 20899-8422, USA.

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http://stacks.iop.org/1402-4896/91/i=2/a=025401?key=crossref
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http://dx.doi.org/10.1088/0031-8949/91/2/025401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912052PMC
February 2016

Hereditary Influence in Thoracic Aortic Aneurysm and Dissection.

Circulation 2016 Jun;133(24):2516-28

From Thoracic Aortic Center (E.M.I., C.L.L.C., M.E.L.), Cardiovascular Genetics Program (M.E.L.), Cardiovascular Research Center (C.L.L.C., M.E.L.), and Cardiology Division (E.M.I., C.L.L.C., M.E.L.), Department of Medicine, and Pediatric Cardiology Division, Department of Pediatrics (M.E.L.), Massachusetts General Hospital, Harvard Medical School, Boston.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.009762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031368PMC
June 2016

Characteristics and Outcomes of Ascending Versus Descending Thoracic Aortic Aneurysms.

Am J Cardiol 2016 05 2;117(10):1683-1690. Epub 2016 Mar 2.

Massachusetts General Hospital Thoracic Aortic Center, Harvard Medical School, Boston, Massachusetts; Division of Cardiology, Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2016.02.048DOI Listing
May 2016

Embryonic Development of the Bicuspid Aortic Valve.

J Cardiovasc Dev Dis 2015 Dec 2;2(4):248-272. Epub 2015 Oct 2.

Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St., Th724, Boston, MA 02115, USA.

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http://dx.doi.org/10.3390/jcdd2040248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438177PMC
December 2015

Risk of rupture or dissection in descending thoracic aortic aneurysm.

Circulation 2015 Oct 2;132(17):1620-9. Epub 2015 Sep 2.

From Division of Cardiac Surgery (J.B.K., T.M., T.M.S.), Thoracic Aortic Center (J.B.K., K.K., T.M., E.M.I., R.P.C., T.M.S.), Cardiology Division (M.E.L., E.M.I.), Pediatric Cardiology (M.E.L.), and Vascular and Endovascular Surgery (R.P.C.), Massachusetts General Hospital, Harvard Medical School, Boston; and Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea (J.B.K., M.E.L.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.015177DOI Listing
October 2015

Glycogen synthase kinase-3β modulation of glucocorticoid responsiveness in COPD.

Am J Physiol Lung Cell Mol Physiol 2015 Nov 28;309(10):L1112-23. Epub 2015 Aug 28.

University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Department of Pulmonology, Groningen, The Netherlands; and University of Groningen, University Medical Center Groningen, Groningen, Groningen Research Institute for Asthma Research Institute, Groningen, The Netherlands.

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http://dx.doi.org/10.1152/ajplung.00077.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652154PMC
November 2015

Marfan syndrome is associated with recurrent dissection of the dissected aorta.

Ann Thorac Surg 2015 May 25;99(5):1616-23. Epub 2015 Mar 25.

Cardiology Division, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts; MGH Thoracic Aortic Center, Massachusetts General Hospital, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.athoracsur.2014.12.066DOI Listing
May 2015

LincRNA signatures in human lymphocytes.

Nat Immunol 2015 Mar;16(3):220-2

Department of Pharmacy and Pharmacology, University of Bath, Bath, UK.

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http://dx.doi.org/10.1038/ni.3106DOI Listing
March 2015

Divergent signalling pathways regulate lipopolysaccharide-induced eRNA expression in human monocytic THP1 cells.

FEBS Lett 2015 Jan 29;589(3):396-406. Epub 2014 Dec 29.

Department of Pharmacy and Pharmacology, University of Bath, Bath BA2 7AY, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.febslet.2014.12.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306547PMC
January 2015

Enhanced enzyme stability through site-directed covalent immobilization.

J Biotechnol 2015 Jan 24;193:83-90. Epub 2014 Nov 24.

Department of Chemical Engineering, Brigham Young University, Provo, UT, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jbiotec.2014.10.039DOI Listing
January 2015

Serum soluble bone turnover biomarkers in psoriatic arthritis and psoriatic spondyloarthropathy.

J Rheumatol 2015 Jan 1;42(1):21-30. Epub 2014 Nov 1.

From the Royal National Hospital for Rheumatic Diseases, and the University of Bath, Bath, UK.D.R. Jadon, MRCP, Research Fellow, Rheumatology; E. Korendowych, FRCP, Consultant Rheumatologist; R. Sengupta, FRCP, Consultant Rheumatologist, Royal National Hospital for Rheumatic Diseases; A.L. Nightingale, PhD, Research Fellow; M.A. Lindsay, PhD, Professor, Pharmacy and Pharmacology, University of Bath; N.J. McHugh, FRCP, Consultant Rheumatologist, Royal National Hospital for Rheumatic Diseases, and the University of Bath.

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http://www.jrheum.org/content/early/2014/10/28/jrheum.140223
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http://www.jrheum.org/cgi/doi/10.3899/jrheum.140223
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http://dx.doi.org/10.3899/jrheum.140223DOI Listing
January 2015

The genetic basis of aortic aneurysm.

Cold Spring Harb Perspect Med 2014 Sep 2;4(9):a015909. Epub 2014 Sep 2.

McKusick-Nathans Institute of Genetic Medicine, Departments of Pediatrics, Medicine, and Molecular Biology & Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205 Howard Hughes Medical Institute, Baltimore, Maryland 21205.

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http://dx.doi.org/10.1101/cshperspect.a015909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143103PMC
September 2014

Long non-coding RNAs in the regulation of the immune response.

Trends Immunol 2014 Sep 8;35(9):408-19. Epub 2014 Aug 8.

Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, UK. Electronic address:

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http://dx.doi.org/10.1016/j.it.2014.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106471PMC
September 2014

Emerging role of MicroRNAs and long noncoding RNAs in respiratory disease.

Chest 2014 Jul;146(1):193-204

Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath, England. Electronic address:

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http://journal.publications.chestnet.org/data/Journals/CHEST
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http://linkinghub.elsevier.com/retrieve/pii/S001236921548764
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http://dx.doi.org/10.1378/chest.13-2736DOI Listing
July 2014

Long non-coding RNAs and enhancer RNAs regulate the lipopolysaccharide-induced inflammatory response in human monocytes.

Nat Commun 2014 Jun 9;5:3979. Epub 2014 Jun 9.

1] Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, BA2 7AY Bath, UK [2] Respiratory Research Group, University Hospital of South Manchester, University of Manchester, Southmoor Road, Manchester M23 9LY, UK [3] Airways Disease, National Heart and Lung Institute, Imperial College, London SW3 6LY, UK.

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http://dx.doi.org/10.1038/ncomms4979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061460PMC
June 2014

Role of non-coding RNAs in maintaining primary airway smooth muscle cells.

Respir Res 2014 May 16;15:58. Epub 2014 May 16.

Experimental Studies, National Heart and Lung Institute, Imperial College, London & Royal Brompton NIHR Biomedical Research Unit, Dovehouse Street, London SW3 6LY, UK.

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http://dx.doi.org/10.1186/1465-9921-15-58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039655PMC
May 2014

LMNA-associated cardiocutaneous progeria: an inherited autosomal dominant premature aging syndrome with late onset.

Am J Med Genet A 2013 Jul 10;161A(7):1599-611. Epub 2013 May 10.

Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1002/ajmg.a.35971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740161PMC
July 2013

Transcriptome analysis shows activation of circulating CD8+ T cells in patients with severe asthma.

J Allergy Clin Immunol 2012 Jan 13;129(1):95-103. Epub 2011 Sep 13.

Respiratory Research Group, Faculty of Medical and Human Sciences, University of Manchester, Manchester, United Kingdom.

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http://linkinghub.elsevier.com/retrieve/pii/S009167491101310
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http://dx.doi.org/10.1016/j.jaci.2011.08.011DOI Listing
January 2012

Lessons on the pathogenesis of aneurysm from heritable conditions.

Nature 2011 May;473(7347):308-16

Division of Pediatric Cardiology, Department of Pediatrics, Johns Hopkins Medical Institutions, Baltimore, Maryland 21205-1832, USA.

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http://dx.doi.org/10.1038/nature10145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622871PMC
May 2011

Measuring the action of CPP-siRNA conjugates in the lung.

Methods Mol Biol 2011 ;683:417-29

Biotherapeutics, Pfizer Global Research and Development, Pfizer Inc, Sandwich, Kent, UK.

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http://dx.doi.org/10.1007/978-1-60761-919-2_30DOI Listing
February 2011

Analysis of 8681 neonates with transposition of the great arteries: outcomes with and without Rashkind balloon atrial septostomy.

Cardiol Young 2010 Aug 17;20(4):373-80. Epub 2010 May 17.

Center for Pediatric Surgical Clinical Trials & Outcomes Research, Division of Pediatric Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1017/S1047951110000296DOI Listing
August 2010

MicroRNAs and the regulation of fibrosis.

FEBS J 2010 May;277(9):2015-21

Department of Genetics and Molecular Biology, Xi'an Jiaotong University, Shaanxi, China.

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http://dx.doi.org/10.1111/j.1742-4658.2010.07632.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963651PMC
May 2010

Regeneration next: toward heart stem cell therapeutics.

Cell Stem Cell 2009 Oct;5(4):364-77

Cardiovascular Research Center, Massachusetts General Hospital, Charles River Plaza/CPZN 3200, 185 Cambridge Street, Boston, MA 02114-2790, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S193459090900449
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October 2009

Divergent intracellular pathways regulate interleukin-1beta-induced miR-146a and miR-146b expression and chemokine release in human alveolar epithelial cells.

FEBS Lett 2009 Oct 26;583(20):3349-55. Epub 2009 Sep 26.

Airways Disease, National Heart and Lung Institute, Imperial College, London SW3 6LY, UK.

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http://dx.doi.org/10.1016/j.febslet.2009.09.038DOI Listing
October 2009

Quality: the Mayo Clinic approach.

Am J Med Qual 2009 Sep-Oct;24(5):428-40. Epub 2009 Jul 7.

Department of Radiology, Mayo Clinic Rochester, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1177/1062860609339521DOI Listing
November 2009

microRNAs and the immune response.

Curr Opin Pharmacol 2009 Aug 12;9(4):514-20. Epub 2009 Jun 12.

NIHR Respiratory Translational Research Facility, University of Manchester, 2nd Floor Education and Research Centre, Wythenshawe Hospital, Southmoor Road, Manchester M23 9LT, UK.

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http://dx.doi.org/10.1016/j.coph.2009.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742742PMC
August 2009

Targeting the lung using siRNA and antisense based oligonucleotides.

Curr Pharm Des 2008 ;14(34):3620-7

Respiratory Research Group, Wythenshawe Hospital, School of Translational Medicine, University of Manchester, M23 9LT, UK.

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http://dx.doi.org/10.2174/138161208786898851DOI Listing
February 2009

Role of miRNA-146a in the regulation of the innate immune response and cancer.

Biochem Soc Trans 2008 Dec;36(Pt 6):1211-5

Biopharmaceutics Research Group, Airway Disease, National Heart and Lung Institute, Imperial College London, London, UK.

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December 2008

Role of miRNA-146a in the regulation of the innate immune response and cancer.

Biochem Soc Trans 2008 Dec;36(Pt 6):1211-5

Biopharmaceutics Research Group, Airway Disease, National Heart and Lung Institute, Imperial College London, London, UK.

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December 2008

microRNAs and the immune response.

Authors:
Mark A Lindsay

Trends Immunol 2008 Jul;29(7):343-51

Respiratory Research Group, Wythenshawe Hospital, School of Translational Sciences, University of Manchester M23 9LT, UK.

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July 2008

Rapid changes in microRNA-146a expression negatively regulate the IL-1beta-induced inflammatory response in human lung alveolar epithelial cells.

J Immunol 2008 Apr;180(8):5689-98

Biopharmaceutics Research Group, Airways Disease, National Heart and Lung Institute, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.180.8.5689DOI Listing
April 2008

microRNA expression in the aging mouse lung.

BMC Genomics 2007 Jun 15;8:172. Epub 2007 Jun 15.

Biopharmaceutics Research Group, Airway Disease, National Heart and Lung Institute, Imperial College, London, UK.

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http://dx.doi.org/10.1186/1471-2164-8-172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1905919PMC
June 2007

MALDI-TOF mass spectral analysis of siRNA degradation in serum confirms an RNAse A-like activity.

Mol Biosyst 2007 Jan 20;3(1):43-50. Epub 2006 Nov 20.

Medical Research Council, Laboratory of Molecular Biology, Hills Road, Cambridge, UKCB2 2QH.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2682774PMC
January 2007