Publications by authors named "Mark J Smyth"

100Publications

TREM2 marks tumor-associated macrophages.

Signal Transduct Target Ther 2020 Oct 9;5(1):233. Epub 2020 Oct 9.

QIMR Berghofer Medical Research Institute, Herston, 4006, QLD, Australia.

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http://dx.doi.org/10.1038/s41392-020-00356-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7547002PMC
October 2020

Targeting immune checkpoints in hematological malignancies.

J Hematol Oncol 2020 08 12;13(1):111. Epub 2020 Aug 12.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, Queensland, 4006, Australia.

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http://dx.doi.org/10.1186/s13045-020-00947-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7425174PMC
August 2020

Adoptive T Cell Therapy Targeting Different Gene Products Reveals Diverse and Context-Dependent Immune Evasion in Melanoma.

Immunity 2020 Sep 3;53(3):564-580.e9. Epub 2020 Aug 3.

Institute of Experimental Oncology (IEO), Medical Faculty, University Hospital Bonn, University of Bonn, Bonn 53105, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2020.07.007DOI Listing
September 2020

Targeting CD39 in cancer.

Nat Rev Immunol 2020 Dec 29;20(12):739-755. Epub 2020 Jul 29.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1038/s41577-020-0376-4DOI Listing
December 2020

The NK cell-cancer cycle: advances and new challenges in NK cell-based immunotherapies.

Nat Immunol 2020 08 20;21(8):835-847. Epub 2020 Jul 20.

Translational Research Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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http://dx.doi.org/10.1038/s41590-020-0728-zDOI Listing
August 2020

Cancer immunoediting and immune dysregulation in multiple myeloma.

Blood 2020 Jul 9. Epub 2020 Jul 9.

INSERM, Toulouse, France.

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http://dx.doi.org/10.1182/blood.2020006540DOI Listing
July 2020

IL15 Stimulation with TIGIT Blockade Reverses CD155-mediated NK-Cell Dysfunction in Melanoma.

Clin Cancer Res 2020 Oct 26;26(20):5520-5533. Epub 2020 Jun 26.

Division of Hematology/Oncology, Department of Medicine, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-20-0575DOI Listing
October 2020

Natural Killers out of Thin Air.

Immunity 2020 Jun;52(6):895-897

QIMR Berghofer Medical Research Institute, Herston, 4006 QLD, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2020.05.007DOI Listing
June 2020

Cancer-killing, decoy-resistant interleukin-18.

Immunol Cell Biol 2020 07 13;98(6):434-436. Epub 2020 Jun 13.

QIMR Berghofer Medical Research Institute, Herston, QLD, 4006, Australia.

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http://dx.doi.org/10.1111/imcb.12359DOI Listing
July 2020

ACKR4 restrains antitumor immunity by regulating CCL21.

J Exp Med 2020 Jun;217(6)

Chemokine Biology Laboratory, Department of Molecular and Biomedical Science, School of Biological Sciences, The University of Adelaide, Adelaide, South Australia, Australia.

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http://dx.doi.org/10.1084/jem.20190634DOI Listing
June 2020

Targeting an adenosine-mediated "don't eat me signal" augments anti-lymphoma immunity by anti-CD20 monoclonal antibody.

Leukemia 2020 10 8;34(10):2708-2721. Epub 2020 Apr 8.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, 4006, QLD, Australia.

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http://dx.doi.org/10.1038/s41375-020-0811-3DOI Listing
October 2020

Innate Cancer Immunoediting.

J Invest Dermatol 2020 04;140(4):745-747

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2019.09.015DOI Listing
April 2020

Control of Metastases via Myeloid CD39 and NK Cell Effector Function.

Cancer Immunol Res 2020 03 28;8(3):356-367. Epub 2020 Jan 28.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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http://dx.doi.org/10.1158/2326-6066.CIR-19-0749DOI Listing
March 2020

Tumor intrinsic and extrinsic immune functions of CD155.

Semin Cancer Biol 2020 10 26;65:189-196. Epub 2019 Dec 26.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, QLD 4006, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2019.11.013DOI Listing
October 2020

MAIT Cells Promote Tumor Initiation, Growth, and Metastases via Tumor MR1.

Cancer Discov 2020 01 11;10(1):124-141. Epub 2019 Dec 11.

Cancer Immunoregulation and Immunotherapy Laboratory, QIMR Berghofer Medical Research Institute, Herston, Australia.

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http://dx.doi.org/10.1158/2159-8290.CD-19-0569DOI Listing
January 2020

YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma.

Mol Cancer 2019 11 18;18(1):163. Epub 2019 Nov 18.

Department of Liver Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200127, China.

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http://dx.doi.org/10.1186/s12943-019-1082-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6859620PMC
November 2019

Blockade of ErbB2 and PD-L1 using a bispecific antibody to improve targeted anti-ErbB2 therapy.

Oncoimmunology 2019 26;8(11):e1648171. Epub 2019 Aug 26.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland Australia.

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http://dx.doi.org/10.1080/2162402X.2019.1648171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791437PMC
August 2019

Myeloid immunosuppression and immune checkpoints in the tumor microenvironment.

Cell Mol Immunol 2020 01 14;17(1):1-12. Epub 2019 Oct 14.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, 4006, QLD, Australia.

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http://dx.doi.org/10.1038/s41423-019-0306-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952382PMC
January 2020

Dual targeting of RANKL and PD-1 with a bispecific antibody improves anti-tumor immunity.

Clin Transl Immunology 2019 27;8(10):e01081. Epub 2019 Sep 27.

Immunology in Cancer and Infection Laboratory QIMR Berghofer Medical Research Institute Herston Qld Australia.

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http://dx.doi.org/10.1002/cti2.1081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763724PMC
September 2019

Infiltrating Myeloid Cells Drive Osteosarcoma Progression via GRM4 Regulation of IL23.

Cancer Discov 2019 11 16;9(11):1511-1519. Epub 2019 Sep 16.

The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.

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http://dx.doi.org/10.1158/2159-8290.CD-19-0154DOI Listing
November 2019

The role of NK cells and CD39 in the immunological control of tumor metastases.

Oncoimmunology 2019 2;8(6):e1593809. Epub 2019 Apr 2.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Australia.

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http://dx.doi.org/10.1080/2162402X.2019.1593809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492967PMC
April 2019

Timing of neoadjuvant immunotherapy in relation to surgery is crucial for outcome.

Oncoimmunology 2019 1;8(5):e1581530. Epub 2019 Mar 1.

Cancer Immunoregulation and Immunotherapy Laboratory, QIMR Berghofer Medical Research Institute, Herston, Australia.

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https://www.tandfonline.com/doi/full/10.1080/2162402X.2019.1
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http://dx.doi.org/10.1080/2162402X.2019.1581530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492961PMC
March 2019

The Promise of Neoadjuvant Immunotherapy and Surgery for Cancer Treatment.

Clin Cancer Res 2019 10 30;25(19):5743-5751. Epub 2019 Apr 30.

Cancer Immunoregulation and Immunotherapy Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-18-2641DOI Listing
October 2019

Hide and seek: Plasticity of innate lymphoid cells in cancer.

Semin Immunol 2019 02 9;41:101273. Epub 2019 Apr 9.

Immunology in Cancer and Infection, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia; School of Medicine, University of Queensland, Herston, Queensland, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.smim.2019.04.001DOI Listing
February 2019

Batf3 DCs and type I IFN are critical for the efficacy of neoadjuvant cancer immunotherapy.

Oncoimmunology 2019 22;8(2):e1546068. Epub 2018 Nov 22.

Cancer Immunoregulation and Immunotherapy Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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http://dx.doi.org/10.1080/2162402X.2018.1546068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343771PMC
November 2018

An observational study of concomitant immunotherapies and denosumab in patients with advanced melanoma or lung cancer.

Oncoimmunology 2018 5;7(12):e1480301. Epub 2018 Sep 5.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Australia.

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http://dx.doi.org/10.1080/2162402X.2018.1480301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279336PMC
September 2018

Cancer immunoediting and resistance to T cell-based immunotherapy.

Nat Rev Clin Oncol 2019 03;16(3):151-167

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Queensland, Australia.

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http://dx.doi.org/10.1038/s41571-018-0142-8DOI Listing
March 2019

2018 Nobel Prize in physiology or medicine.

Clin Transl Immunology 2018 24;7(10):e1041. Epub 2018 Oct 24.

Cancer Immunoregulation and Immunotherapy QIMR Berghofer Medical Research Institute 300 Herston Road Herston 4006 QLD Australia.

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http://doi.wiley.com/10.1002/cti2.1041
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http://dx.doi.org/10.1002/cti2.1041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200707PMC
October 2018

Roles of the RANKL-RANK axis in antitumour immunity - implications for therapy.

Nat Rev Clin Oncol 2018 11;15(11):676-693

Cancer Immunoregulation and Immunotherapy Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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http://www.nature.com/articles/s41571-018-0095-y
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http://dx.doi.org/10.1038/s41571-018-0095-yDOI Listing
November 2018

Overcoming Acquired PD-1/PD-L1 Resistance with CD38 Blockade.

Cancer Discov 2018 09;8(9):1066-1068

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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http://cancerdiscovery.aacrjournals.org/lookup/doi/10.1158/2
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http://dx.doi.org/10.1158/2159-8290.CD-18-0798DOI Listing
September 2018

Experimental Lung Metastases in Mice Are More Effectively Inhibited by Blockade of IL23R than IL23.

Cancer Immunol Res 2018 08 19;6(8):978-987. Epub 2018 Jun 19.

Cancer Immunoregulation and Immunotherapy Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Australia.

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http://dx.doi.org/10.1158/2326-6066.CIR-18-0011DOI Listing
August 2018

TGFβ shuts the door on T cells.

Br J Cancer 2018 07 14;119(1):1-3. Epub 2018 Jun 14.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, QLD, 4006, Australia.

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http://dx.doi.org/10.1038/s41416-018-0122-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035201PMC
July 2018

RANKL blockade improves efficacy of PD1-PD-L1 blockade or dual PD1-PD-L1 and CTLA4 blockade in mouse models of cancer.

Oncoimmunology 2018 14;7(6):e1431088. Epub 2018 Feb 14.

Department of Immunology, Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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http://dx.doi.org/10.1080/2162402X.2018.1431088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5980384PMC
February 2018

Aberrant erythropoiesis fuels tumor growth.

Cell Res 2018 06;28(6):611-612

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, 4006, QLD, Australia.

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http://dx.doi.org/10.1038/s41422-018-0047-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993832PMC
June 2018

Dysregulated IL-18 Is a Key Driver of Immunosuppression and a Possible Therapeutic Target in the Multiple Myeloma Microenvironment.

Cancer Cell 2018 04;33(4):634-648.e5

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, 4006 QLD, Australia; School of Medicine, University of Queensland, St Lucia 4006 QLD, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.02.007DOI Listing
April 2018

Interleukin-12 from CD103 Batf3-Dependent Dendritic Cells Required for NK-Cell Suppression of Metastasis.

Cancer Immunol Res 2017 12 25;5(12):1098-1108. Epub 2017 Oct 25.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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http://cancerimmunolres.aacrjournals.org/lookup/doi/10.1158/
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http://dx.doi.org/10.1158/2326-6066.CIR-17-0341DOI Listing
December 2017

Targeting immunosuppressive adenosine in cancer.

Nat Rev Cancer 2017 12 23;17(12):709-724. Epub 2017 Oct 23.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, 4006, Queensland, Australia.

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http://dx.doi.org/10.1038/nrc.2017.86DOI Listing
December 2017

Cytokine-driven role of Srebps in killer cell metabolism.

Nat Immunol 2017 10;18(11):1183-1184

Immunology of Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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http://dx.doi.org/10.1038/ni.3855DOI Listing
October 2017

CD73 Promotes Resistance to HER2/ErbB2 Antibody Therapy.

Cancer Res 2017 10 30;77(20):5652-5663. Epub 2017 Aug 30.

Centre de Recherche du Centre Hospitalier de l'Université de Montréal, Québec, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-0707DOI Listing
October 2017

Control of Metastasis by NK Cells.

Cancer Cell 2017 08;32(2):135-154

Department of Radiation Oncology, Weill Cornell Medical College, New York, NY 10065, USA; Sandra and Edward Meyer Cancer Center, New York, NY 10065, USA; Université Paris Descartes/Paris V, 75006 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.06.009DOI Listing
August 2017

Interleukin (IL)-12 and IL-23 and Their Conflicting Roles in Cancer.

Cold Spring Harb Perspect Biol 2018 07 2;10(7). Epub 2018 Jul 2.

Cancer Immunoregulation and Immunotherapy Laboratory, QIMR Berghofer Medical Research Institute, Herston 4006, Queensland, Australia.

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http://dx.doi.org/10.1101/cshperspect.a028530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028064PMC
July 2018

PD1 functions by inhibiting CD28-mediated co-stimulation.

Clin Transl Immunology 2017 May 5;6(5):e138. Epub 2017 May 5.

Cancer Immunoregulation and Immunotherapy Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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http://dx.doi.org/10.1038/cti.2017.15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5493584PMC
May 2017

Targeting Adenosine in BRAF-Mutant Melanoma Reduces Tumor Growth and Metastasis.

Cancer Res 2017 09 26;77(17):4684-4696. Epub 2017 Jun 26.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-0393DOI Listing
September 2017

Selective activation of anti-CD73 mechanisms in control of primary tumors and metastases.

Oncoimmunology 2017 5;6(5):e1312044. Epub 2017 Apr 5.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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http://dx.doi.org/10.1080/2162402X.2017.1312044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467999PMC
April 2017

Co-administration of RANKL and CTLA4 Antibodies Enhances Lymphocyte-Mediated Antitumor Immunity in Mice.

Clin Cancer Res 2017 Oct 20;23(19):5789-5801. Epub 2017 Jun 20.

Immunology in Cancer and Infection, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-0606DOI Listing
October 2017

NK cell heparanase controls tumor invasion and immune surveillance.

J Clin Invest 2017 Jun 5;127(7):2777-2788. Epub 2017 Jun 5.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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http://dx.doi.org/10.1172/JCI92958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490772PMC
June 2017

Targeting cytokine signaling checkpoint CIS activates NK cells to protect from tumor initiation and metastasis.

Oncoimmunology 2017 7;6(2):e1267892. Epub 2017 Feb 7.

Immunology of Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia; School of Medicine, The University of Queensland, Herston, Queensland, Australia.

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https://www.tandfonline.com/doi/full/10.1080/2162402X.2016.1
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http://dx.doi.org/10.1080/2162402X.2016.1267892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353935PMC
February 2017

BK Polyomavirus: Clinical Aspects, Immune Regulation, and Emerging Therapies.

Clin Microbiol Rev 2017 04;30(2):503-528

QIMR Berghofer Centre for Immunotherapy and Vaccine Development, Tumour Immunology Laboratory, QIMR Berghofer Medical Research Institute, Herston, QLD, Australia

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http://dx.doi.org/10.1128/CMR.00074-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355639PMC
April 2017

TIGIT and CD96: new checkpoint receptor targets for cancer immunotherapy.

Immunol Rev 2017 03;276(1):112-120

Evergrande Center for Immunologic Diseases and Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1111/imr.12518DOI Listing
March 2017

HDAC Inhibitor Panobinostat Engages Host Innate Immune Defenses to Promote the Tumoricidal Effects of Trastuzumab in HER2 Tumors.

Cancer Res 2017 05 1;77(10):2594-2606. Epub 2017 Mar 1.

Cancer Therapeutics Program, Peter MacCallum Cancer Centre, Victorian Comprehensive Cancer Centre (VCCC), Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-2247DOI Listing
May 2017

IFN-γ is required for cytotoxic T cell-dependent cancer genome immunoediting.

Nat Commun 2017 02 24;8:14607. Epub 2017 Feb 24.

Cancer Immunology Program, Peter MacCallum Cancer Centre, St Andrews Place, East Melbourne, 3002 Victoria, Australia.

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http://dx.doi.org/10.1038/ncomms14607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333095PMC
February 2017

Multiple approaches to immunotherapy - the new pillar of cancer treatment.

Authors:
Mark J Smyth

Immunol Cell Biol 2017 04;95(4):323-324

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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http://dx.doi.org/10.1038/icb.2017.9DOI Listing
April 2017

Targeting cancer-related inflammation in the era of immunotherapy.

Immunol Cell Biol 2017 04 10;95(4):325-332. Epub 2017 Jan 10.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical, Research Institute, Herston, QLD, Australia.

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http://dx.doi.org/10.1038/icb.2016.126DOI Listing
April 2017

Resistance to PD1/PDL1 checkpoint inhibition.

Cancer Treat Rev 2017 Jan 27;52:71-81. Epub 2016 Nov 27.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston 4006, Queensland, Australia; School of Medicine, The University of Queensland, Herston 4006, Queensland, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ctrv.2016.11.007DOI Listing
January 2017

GVHD prevents NK-cell-dependent leukemia and virus-specific innate immunity.

Blood 2017 02 7;129(5):630-642. Epub 2016 Dec 7.

Bone Marrow Transplantation Laboratory, Immunology Department, Queensland Institute of Medical Research (QIMR) Berghofer Medical Research Institute, Brisbane, QLD, Australia.

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http://dx.doi.org/10.1182/blood-2016-08-734020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290987PMC
February 2017

Physicochemical properties that control protein aggregation also determine whether a protein is retained or released from necrotic cells.

Open Biol 2016 11;6(11)

Australian Centre for Blood Diseases, Alfred Medical Research and Education Precinct (AMREP), Monash University, Melbourne, Victoria 3004, Australia.

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http://dx.doi.org/10.1098/rsob.160098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133435PMC
November 2016

Mouse models in oncoimmunology.

Nat Rev Cancer 2016 12 30;16(12):759-773. Epub 2016 Sep 30.

Equipe 11 labelisée par la Ligue Nationale contre le Cancer, INSERM U1138, Centre de Recherche des Cordeliers, 75006 Paris, France.

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http://dx.doi.org/10.1038/nrc.2016.91DOI Listing
December 2016

Agonistic CD40 mAb-Driven IL12 Reverses Resistance to Anti-PD1 in a T-cell-Rich Tumor.

Cancer Res 2016 11 9;76(21):6266-6277. Epub 2016 Sep 9.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-2141DOI Listing
November 2016

Molecular Pathways: Targeting CD96 and TIGIT for Cancer Immunotherapy.

Clin Cancer Res 2016 Nov 12;22(21):5183-5188. Epub 2016 Sep 12.

Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-0933DOI Listing
November 2016

Acquired resistance to anti-PD1 therapy: checkmate to checkpoint blockade?

Genome Med 2016 10 25;8(1):111. Epub 2016 Oct 25.

Cancer Immunoregulation and Immunotherapy Laboratory, QIMR Berghofer Medical Research Institute, Herston, 4006, QLD, Australia.

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http://dx.doi.org/10.1186/s13073-016-0365-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080691PMC
October 2016