Publications by authors named "Mark J Routbort"

86Publications

Inconsistent Intersample ALK FISH Results in Patients with Lung Cancer: Analysis of Potential Causes.

Cancers (Basel) 2020 Jul 14;12(7). Epub 2020 Jul 14.

Departments of Hematopathology, Pathology and Thoracic/Head and Neck Medical Oncology, School of Health Professions, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Houston, TX 77030, USA.

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http://dx.doi.org/10.3390/cancers12071903DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7409019PMC
July 2020

Proficiency Testing of Standardized Samples Shows High Interlaboratory Agreement for Clinical Next Generation Sequencing-Based Hematologic Malignancy Assays With Survey Material-Specific Differences in Variant Frequencies.

Arch Pathol Lab Med 2020 Jan 27. Epub 2020 Jan 27.

From the Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts (Drs Keegan, Lindeman, and Kim); the Departments of Pathology and Microbiology, University of Nebraska Medical Center, Omaha (Dr Bridge); Biostatistics (Mr Long) and Proficiency Testing (Ms Vasalos), ollege of American Pathologists, Northfield, Illinois; the UNC Lineberger Comprehensive Cancer Center (Dr Merker) and the Department of Pathology and Laboratory Medicine (Dr Montgomery), University of North Carolina, Chapel Hill; the Office of the Director, The Joint Pathology Center, Silver Spring, Maryland (Dr Moncur); the Department of Pathology, PierianDx, St Louis, Missouri (Dr Nagarajan); the Department of Pathology and Laboratory Medicine, Strong Memorial Hospital, University of Rochester Medical Center, Rochester, New York (Dr Rothberg); the Department of Hematopathology, MD Anderson Cancer Center, Houston, Texas (Dr Routbort); and the Department of Pathology, Johns Hopkins School of Medicine, Baltimore, Maryland (Dr Xian).

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http://dx.doi.org/10.5858/arpa.2019-0352-CPDOI Listing
January 2020

Comparison of therapy-related myelodysplastic syndrome with ring sideroblasts and de novo myelodysplastic syndrome with ring sideroblasts.

Leuk Res 2019 11 17;86:106227. Epub 2019 Sep 17.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2019.106227DOI Listing
November 2019

TP53 mutations are common in mantle cell lymphoma, including the indolent leukemic non-nodal variant.

Ann Diagn Pathol 2019 Aug 16;41:38-42. Epub 2019 May 16.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.anndiagpath.2019.05.004DOI Listing
August 2019

Proficiency Testing of Standardized Samples Shows Very High Interlaboratory Agreement for Clinical Next-Generation Sequencing-Based Oncology Assays.

Arch Pathol Lab Med 2019 04 30;143(4):463-471. Epub 2018 Oct 30.

From the Departments of Pathology and Laboratory Medicine & Genetics, Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill (Dr Merker); the Departments of Pathology (Drs Devereaux and Montgomery, and Mr Smail) and Genetics (Dr Montgomery), Stanford University School of Medicine, and the Biomedical Informatics Program (Mr Smail), Stanford University, Stanford, California; the Department of Pathology, Massachusetts General Hospital (Dr Iafrate), and the Department of Pathology, Brigham and Women's Hospital (Drs Kim and Lindeman), Harvard University, Boston; the Departments of Pathology and Clinical Laboratory Genetics, The University Health Network and the University of Toronto, Toronto, Ontario, Canada (Dr Kamel-Reid); the Department of Pathology, Walter Reed National Military Medical Center, Bethesda, Maryland (Dr Moncur); PierianDx, St Louis, Missouri (Dr Nagarajan); the Department of Global Medical Affairs, Roche, Tucson, Arizona (Dr Portier); the Departments of Hematopathology (Dr Routbort) and Pathology, Genomic Medicine, and Translational Molecular Pathology (Dr Lazar), he University of Texas MD Anderson Cancer Center, Houston (Dr Routbort); the Department of Pathology, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia (Dr Surrey); and Proficiency Testing, College of American Pathologists, Northfield, Illinois (Ms Vasalos).

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http://www.archivesofpathology.org/doi/10.5858/arpa.2018-033
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http://dx.doi.org/10.5858/arpa.2018-0336-CPDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910717PMC
April 2019

Characterization of chronic myelomonocytic leukemia with TP53 mutations.

Leuk Res 2018 07 31;70:97-99. Epub 2018 May 31.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States.

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http://dx.doi.org/10.1016/j.leukres.2018.05.012DOI Listing
July 2018

Molecular Profile of Advanced Thyroid Carcinomas by Next-Generation Sequencing: Characterizing Tumors Beyond Diagnosis for Targeted Therapy.

Mol Cancer Ther 2018 07 25;17(7):1575-1584. Epub 2018 Apr 25.

Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1535-7163.MCT-17-0871DOI Listing
July 2018

Characterization of TP53 mutations in low-grade myelodysplastic syndromes and myelodysplastic syndromes with a non-complex karyotype.

Eur J Haematol 2017 Dec 20;99(6):536-543. Epub 2017 Oct 20.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://doi.wiley.com/10.1111/ejh.12971
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http://dx.doi.org/10.1111/ejh.12971DOI Listing
December 2017

Identifying Health Information Technology Needs of Oncologists to Facilitate the Adoption of Genomic Medicine: Recommendations From the 2016 American Society of Clinical Oncology Omics and Precision Oncology Workshop.

J Clin Oncol 2017 Sep 24;35(27):3153-3159. Epub 2017 Jul 24.

Kevin S. Hughes, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Edward P. Ambinder, Icahn School of Medicine at Mount Sinai; Peter Paul Yu, Memorial Sloan Kettering Cancer Center, New York, NY; Gregory P. Hess, Symphony Health, Conshohocken; Gregory P. Hess and Susan M. Domchek, University of Pennsylvania, Philadelphia, PA; Peter Paul Yu, Hartford HealthCare Cancer Institute, Hartford, CT; Elmer V. Bernstam, The University of Texas Health Sciences Center at Houston; Mark J. Routbort, MD Anderson Cancer Center, Houston, TX; Jean Rene Clemenceau, Hospital Angeles Pedregal, Mexico City, Mexico; John T. Hamm, Norton Healthcare, Louisville, KY; Phillip G. Febbo, Genomic Health, Redwood City, CA; James L. Chen, Ohio State University, Columbus, OH; and Jeremy L. Warner, Vanderbilt University, Vanderbilt University Medical Center, Nashville, TN.

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http://dx.doi.org/10.1200/JCO.2017.74.1744DOI Listing
September 2017

Characterization of TP53 mutations in clonal cytopenia of undetermined significance.

Am J Hematol 2017 Aug 9;92(8):E175-E177. Epub 2017 Jun 9.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, 77030.

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http://doi.wiley.com/10.1002/ajh.24786
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http://dx.doi.org/10.1002/ajh.24786DOI Listing
August 2017

Validation of quantitative PCR-based assays for detection of gene copy number aberrations in formalin-fixed, paraffin embedded solid tumor samples.

Cancer Genet 2017 04 20;212-213:24-31. Epub 2017 Mar 20.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2017.03.002DOI Listing
April 2017

Retrospective Analysis of Molecular and Immunohistochemical Characterization of 381 Primary Brain Tumors.

J Neuropathol Exp Neurol 2017 03;76(3):179-188

Department of Hematopathology, UT-MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1093/jnen/nlw119DOI Listing
March 2017

A Targeted High-Throughput Next-Generation Sequencing Panel for Clinical Screening of Mutations, Gene Amplifications, and Fusions in Solid Tumors.

J Mol Diagn 2017 03 23;19(2):255-264. Epub 2016 Dec 23.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2016.09.011DOI Listing
March 2017

Big data from small samples: Informatics of next-generation sequencing in cytopathology.

Cancer Cytopathol 2017 Apr 5;125(4):236-244. Epub 2016 Dec 5.

Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1002/cncy.21805DOI Listing
April 2017

How Do We Make Clinical Molecular Testing for Cancer Standard of Care for Pathology Departments?

J Natl Compr Canc Netw 2016 06;14(6):787-92

Departments of Pathology, The University of Texas MD Anderson Cancer Center, Houston Texas

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http://dx.doi.org/10.6004/jnccn.2016.0079DOI Listing
June 2016

Preleukemic phase of chronic myelogenous leukemia: morphologic and immunohistochemical characterization of 7 cases.

Ann Diagn Pathol 2016 Apr 6;21:53-8. Epub 2016 Feb 6.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, United States. Electronic address:

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http://dx.doi.org/10.1016/j.anndiagpath.2015.12.004DOI Listing
April 2016

Next-Generation Sequencing Informatics: Challenges and Strategies for Implementation in a Clinical Environment.

Arch Pathol Lab Med 2016 Sep 22;140(9):958-75. Epub 2016 Feb 22.

From the Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (Drs Roy, LaFramboise, Nikiforov, Nikiforova, and Pantanowitz); the Department of Pathology, MD Anderson Cancer Center, Houston, Texas (Dr Routbort); the Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri (Drs Pfeifer and Nagarajan); PierianDx, St Louis, Missouri (Dr Nagarajan); and the Department of Pathology and Laboratory Medicine, Children's Healthcare of Atlanta, Atlanta, Georgia (Dr Carter).

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http://dx.doi.org/10.5858/arpa.2015-0507-RADOI Listing
September 2016

Principles of analytical validation of next-generation sequencing based mutational analysis for hematologic neoplasms in a CLIA-certified laboratory.

Expert Rev Mol Diagn 2016 15;16(4):461-72. Epub 2016 Feb 15.

a Department of Hematopathology , The University of Texas at M.D. Anderson Cancer Center , Houston , TX , USA.

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http://dx.doi.org/10.1586/14737159.2016.1142374DOI Listing
December 2016

Factors affecting the success of next-generation sequencing in cytology specimens.

Cancer Cytopathol 2015 Nov 31;123(11):659-68. Epub 2015 Jul 31.

Department of Pathology, Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1002/cncy.21597DOI Listing
November 2015

Therapy-Related Myeloid Neoplasms.

Am J Clin Pathol 2015 Aug;144(2):207-18

The Division of Hematopathology, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1309/AJCPU1JO2LYTWUAVDOI Listing
August 2015

Comparison of next-generation sequencing mutation profiling with BRAF and IDH1 mutation-specific immunohistochemistry.

Am J Surg Pathol 2015 Apr;39(4):454-61

Departments of *Hematopathology †Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1097/PAS.0000000000000325DOI Listing
April 2015

Lung adenocarcinoma with concurrent KRAS mutation and ALK rearrangement responding to crizotinib: case report.

Int J Biol Markers 2015 May 26;30(2):e254-7. Epub 2015 May 26.

1 Department of Medical Oncology, State Oncology Center, ISSEMyM, Toluca - México.

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http://dx.doi.org/10.5301/jbm.5000127DOI Listing
May 2015

Implementation of biomarker-driven cancer therapy: existing tools and remaining gaps.

Discov Med 2014 Feb;17(92):101-14

Sheikh Khalifa Al Nahyan Ben Zayed Institute for Personalized Cancer Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4160907PMC
February 2014

TET2 mutations, myelodysplastic features, and a distinct immunoprofile characterize blastic plasmacytoid dendritic cell neoplasm in the bone marrow.

Am J Hematol 2013 Dec 30;88(12):1055-61. Epub 2013 Sep 30.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas; Department of Pathology, King Saud University, Riyadh, Saudi Arabia.

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http://doi.wiley.com/10.1002/ajh.23567
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http://dx.doi.org/10.1002/ajh.23567DOI Listing
December 2013

Clinical validation of a next-generation sequencing screen for mutational hotspots in 46 cancer-related genes.

J Mol Diagn 2013 Sep 26;15(5):607-22. Epub 2013 Jun 26.

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1016/j.jmoldx.2013.05.003DOI Listing
September 2013

Pulmonary granulocytic sarcoma (chloroma) mimicking an opportunistic infection in a patient with acute myeloid leukemia.

Ann Hematol 2014 Feb 30;93(2):327-8. Epub 2013 Apr 30.

Hospital A.C. Camargo, Department of Imaging, Rua Paulo Orozimbo, 726, Aclimação, 01535-001, São Paulo, SP, Brazil,

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http://dx.doi.org/10.1007/s00277-013-1768-3DOI Listing
February 2014

Low rates of hepatitis B virus screening at the onset of chemotherapy.

J Oncol Pract 2012 Jul 12;8(4):e32-9. Epub 2012 Jun 12.

The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1200/JOP.2011.000450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396827PMC
July 2012

The p53 tumor suppressor network in cancer and the therapeutic modulation of cell death.

Apoptosis 2009 Apr;14(4):336-47

Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1007/s10495-009-0327-9DOI Listing
April 2009

Lymphomas involving the breast: a study of 106 cases comparing localized and disseminated neoplasms.

Am J Surg Pathol 2008 Sep;32(9):1299-309

Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.

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http://dx.doi.org/10.1097/PAS.0b013e318165eb50DOI Listing
September 2008

Primary adrenal natural killer/T-cell nasal type lymphoma: first case report in adults.

Am J Hematol 2007 Apr;82(4):299-303

Division of Medical Oncology, The University of Texas, M.D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1002/ajh.20811DOI Listing
April 2007

Pancreatic and bile duct brushing cytology in 1000 cases: review of findings and comparison of preparation methods.

Cancer 2006 Aug;108(4):231-8

Department of Pathology, University of North Carolina, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1002/cncr.21842DOI Listing
August 2006

Primary pancreatic lymphoma evaluated by fine-needle aspiration: findings in 14 cases.

Am J Clin Pathol 2004 Jun;121(6):898-903

Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1309/UAD9-PYFU-A82X-9R9UDOI Listing
June 2004